TY - JOUR A1 - Enning, Manfred T1 - FlexCargoRail – Ohne Diesel in die Letzte Meile JF - Schienenverkehr – sicher, leise, effizient : InnoTrans, Berlin 2008 / Hrsg.: Bundesministerium für Wirtschaft und Technologie, Referat Öffentlichkeitsarbeit Y1 - 2008 N1 - Innovationspolitik, Informationsgesellschaft, Telekommunikation SP - 49 EP - 52 CY - Berlin ER - TY - JOUR A1 - Enning, Manfred T1 - Einzelwagenkonzept für die letzte Meile : „FlexCargoRail“ sieht autarke Fahrten von Waggons mit Rangiergeschwindigkeit vor. Massive Effizienzgewinne locken JF - Deutsche Verkehrs-Zeitung : DVZ / Logistik auf der Schiene (2008) Y1 - 2008 SN - 0342-166X N1 - vom 8.11.2008 ER - TY - JOUR A1 - Enning, Manfred T1 - Flexcargorail - ein Fahrzeugsystem für effizienten Einzelwagenverkehr / Baier, Martin ; Enning, Manfred JF - Logistik Management. 8 (2006), H. 3 Y1 - 2006 SN - 1436-6231 SP - 28 EP - 42 ER - TY - JOUR A1 - Enning, Manfred T1 - Vom "König der Landstraße" zur "Ameise 4.0" JF - ETR - Eisenbahntechnische Rundschau N2 - Auf Eisenbahn- und Logistikkonferenzen werden gelegentlich Videos von Blattschneiderameisen gezeigt, die effizient und selbstorganisiert große Mengen Material durch den Dschungel transportieren. Daran sollen wir uns ein Beispiel nehmen. Y1 - 2017 SN - 0013-2845 VL - 66 IS - 1/2 SP - 3 PB - DVV Media Group CY - Hamburg ER - TY - JOUR A1 - Engemann, Heiko A1 - Du, Shengzhi A1 - Kallweit, Stephan A1 - Cönen, Patrick A1 - Dawar, Harshal T1 - OMNIVIL - an autonomous mobile manipulator for flexible production JF - Sensors Y1 - 2020 SN - 1424-8220 U6 - https://doi.org/10.3390/s20247249 N1 - Special issue: Sensor Networks Applications in Robotics and Mobile Systems VL - 20 IS - 24, art. no. 7249 SP - 1 EP - 30 PB - MDPI CY - Basel ER - TY - JOUR A1 - Engemann, Heiko A1 - Cönen, Patrick A1 - Dawar, Harshal A1 - Du, Shengzhi A1 - Kallweit, Stephan T1 - A robot-assisted large-scale inspection of wind turbine blades in manufacturing using an autonomous mobile manipulator JF - Applied Sciences N2 - Wind energy represents the dominant share of renewable energies. The rotor blades of a wind turbine are typically made from composite material, which withstands high forces during rotation. The huge dimensions of the rotor blades complicate the inspection processes in manufacturing. The automation of inspection processes has a great potential to increase the overall productivity and to create a consistent reliable database for each individual rotor blade. The focus of this paper is set on the process of rotor blade inspection automation by utilizing an autonomous mobile manipulator. The main innovations include a novel path planning strategy for zone-based navigation, which enables an intuitive right-hand or left-hand driving behavior in a shared human–robot workspace. In addition, we introduce a new method for surface orthogonal motion planning in connection with large-scale structures. An overall execution strategy controls the navigation and manipulation processes of the long-running inspection task. The implemented concepts are evaluated in simulation and applied in a real-use case including the tip of a rotor blade form. KW - mobile manipulation KW - large-scale inspection KW - wind turbine production KW - autonomous navigation KW - surface-orthogonal path planning Y1 - 2021 U6 - https://doi.org/10.3390/app11199271 SN - 2076-3417 N1 - Belongs to the Special Issue "Advances in Industrial Robotics and Intelligent Systems" VL - 11 IS - 19 SP - 1 EP - 22 PB - MDPI CY - Basel ER - TY - JOUR A1 - Engels, Elmar A1 - Wiendahl, H.-P. A1 - Doege, E. T1 - Universelle hydraulische Try-Out Presse / Teilprojekt A6 / Wiendahl, H.-P. ; Doege, E. ; Engels, E. JF - Tagungsband : 12. Oktober 1999, Leibnizhaus Hannover / Sonderforschungsbereich 384 Verfügbarkeitssicherung Reaktionsschneller Produktionssysteme, Universität Hannover. Hrsg.: H.-P. Wiendahl ; M. Röhrig Y1 - 1999 SN - 3-00-005495-2 N1 - Industriekolloquium Verfügbarkeit <1999, Hannover> ; Sonderforschungsbereich Verfügbarkeitssicherung Reaktionsschneller Produktionssysteme CY - Hannover ER - TY - JOUR A1 - Engels, Elmar A1 - Krauskopf, S. T1 - Innovation in Motion-Logic programming - a versatile interface JF - Proceedings to the 12th International Workshop on Research and Education in Mechatronics, REM 2011, Kocaeli, Turkey, 15.09.-16.09.2011 Y1 - 2011 SN - 978-975-8047-96-3 PB - - ER - TY - JOUR A1 - Engels, Elmar A1 - Doege, Eckhart T1 - Pressen - Vergleich zwischen Raumlenker- und Exzenterantrieb / Doege, Eckhart ; Engels, Elmar JF - Blech, Rohre, Profile : Herstellen, Verarbeiten und Veredeln von Band, Blech, Rohren und Profilen. 46 (1999), H. 7-8 Y1 - 1999 SN - 0006-4688 SP - 31 EP - 37 ER - TY - JOUR A1 - Engels, Elmar A1 - Doege, Eckhart T1 - Pressen - Hubzahlregelung an Schnelläuferpressen mit Fuzzy-Reglern / Doege, Eckhart ; Engels, Elmar JF - Blech, Rohre, Profile : Herstellen, Verarbeiten und Veredeln von Band, Blech, Rohren und Profilen. 45 (1998), H. 11 Y1 - 1998 SN - 0006-4688 SP - 47 EP - 49 ER - TY - JOUR A1 - Engels, Elmar A1 - Doege, E. A1 - Elend, L. E. T1 - Modifizierte Ziehkissenklemmung erweitert Pressen-Arbeitsbereich / Doege, E. ; Elend, L. E. ; Engels, E. JF - Maschinenmarkt. 106 (2000), H. 7 Y1 - 2000 SN - 0341-5775 SP - 30 EP - 33 ER - TY - JOUR A1 - Engels, Elmar A1 - Doege, E. T1 - Optimizing the number of strokes for punching machines using a fuzzy controlled electrohydraulic damping system / Doege, E. ; Engels, E. JF - ICME 98, CIRP International Seminar on Intelligent Computation in Manufacturing Engineering, Proceedings, Capri, IT, Jul 1-3, 1998 Y1 - 1998 SP - 471 EP - 478 CY - Capri ER - TY - JOUR A1 - Engels, Elmar T1 - Reduzierung der horizontalen Massenkräfte bei Pressen mit Raumlenkerantrieb JF - UTF-science : Forschungsmagazin für die Produktionstechnik. 1 (2000), H. 3 Y1 - 2000 SP - 17 S. ER - TY - JOUR A1 - Engeln-Müllges, Gisela T1 - Entartungsbedingungen für Gleitflächennomogramme und Nomographierbarkeitsbedingungen für Fluchtebenennomogramme JF - ZAMM ‐ Journal of Applied Mathematics and Mechanics / Zeitschrift für Angewandte Mathematik und Mechanik Y1 - 1982 U6 - https://doi.org/10.1002/zamm.19820620203 SN - 1521-4001 VL - 62 IS - 2 SP - 77 EP - 93 ER - TY - JOUR A1 - Engelmann, Ulrich M. A1 - Simsek, Beril A1 - Shalaby, Ahmed A1 - Krause, Hans-Joachim T1 - Key contributors to signal generation in frequency mixing magnetic detection (FMMD): an in silico study JF - Sensors N2 - Frequency mixing magnetic detection (FMMD) is a sensitive and selective technique to detect magnetic nanoparticles (MNPs) serving as probes for binding biological targets. Its principle relies on the nonlinear magnetic relaxation dynamics of a particle ensemble interacting with a dual frequency external magnetic field. In order to increase its sensitivity, lower its limit of detection and overall improve its applicability in biosensing, matching combinations of external field parameters and internal particle properties are being sought to advance FMMD. In this study, we systematically probe the aforementioned interaction with coupled Néel–Brownian dynamic relaxation simulations to examine how key MNP properties as well as applied field parameters affect the frequency mixing signal generation. It is found that the core size of MNPs dominates their nonlinear magnetic response, with the strongest contributions from the largest particles. The drive field amplitude dominates the shape of the field-dependent response, whereas effective anisotropy and hydrodynamic size of the particles only weakly influence the signal generation in FMMD. For tailoring the MNP properties and parameters of the setup towards optimal FMMD signal generation, our findings suggest choosing large particles of core sizes dc > 25 nm nm with narrow size distributions (σ < 0.1) to minimize the required drive field amplitude. This allows potential improvements of FMMD as a stand-alone application, as well as advances in magnetic particle imaging, hyperthermia and magnetic immunoassays. KW - key performance indicators KW - magnetic biosensing KW - coupled Néel–Brownian relaxation dynamics KW - frequency mixing magnetic detection KW - magnetic relaxation KW - micromagnetic simulation KW - magnetic nanoparticles Y1 - 2024 U6 - https://doi.org/10.3390/s24061945 SN - 1424-8220 N1 - This article belongs to the Special Issue "Advances in Magnetic Sensors and Their Applications" VL - 24 IS - 6 PB - MDPI CY - Basel ER - TY - JOUR A1 - Engelmann, Ulrich M. A1 - Shasha, Carolyn A1 - Teeman, Eric A1 - Slabu, Iona A1 - Krishnan, Kannan M. T1 - Predicting size-dependent heating efficiency of magnetic nanoparticles from experiment and stochastic Néel-Brown Langevin simulation JF - Journal of Magnetism and Magnetic Materials Y1 - 2019 U6 - https://doi.org/10.1016/j.jmmm.2018.09.041 SN - 0304-8853 VL - 471 IS - 1 SP - 450 EP - 456 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Engelmann, Ulrich M. A1 - Shalaby, Ahmed A1 - Shasha, Carolyn A1 - Krishnan, Kannan M. A1 - Krause, Hans-Joachim T1 - Comparative modeling of frequency mixing measurements of magnetic nanoparticles using micromagnetic simulations and Langevin theory JF - Nanomaterials N2 - Dual frequency magnetic excitation of magnetic nanoparticles (MNP) enables enhanced biosensing applications. This was studied from an experimental and theoretical perspective: nonlinear sum-frequency components of MNP exposed to dual-frequency magnetic excitation were measured as a function of static magnetic offset field. The Langevin model in thermodynamic equilibrium was fitted to the experimental data to derive parameters of the lognormal core size distribution. These parameters were subsequently used as inputs for micromagnetic Monte-Carlo (MC)-simulations. From the hysteresis loops obtained from MC-simulations, sum-frequency components were numerically demodulated and compared with both experiment and Langevin model predictions. From the latter, we derived that approximately 90% of the frequency mixing magnetic response signal is generated by the largest 10% of MNP. We therefore suggest that small particles do not contribute to the frequency mixing signal, which is supported by MC-simulation results. Both theoretical approaches describe the experimental signal shapes well, but with notable differences between experiment and micromagnetic simulations. These deviations could result from Brownian relaxations which are, albeit experimentally inhibited, included in MC-simulation, or (yet unconsidered) cluster-effects of MNP, or inaccurately derived input for MC-simulations, because the largest particles dominate the experimental signal but concurrently do not fulfill the precondition of thermodynamic equilibrium required by Langevin theory. KW - Magnetic nanoparticles KW - Frequency mixing magnetic detection KW - Langevin theory KW - Micromagnetic simulation KW - Nonequilibrium dynamics Y1 - 2021 SN - 2079-4991 U6 - https://doi.org/10.3390/nano11051257 N1 - This article belongs to the Special Issue Applications and Properties of Magnetic Nanoparticles VL - 11 IS - 5 SP - 1 EP - 16 PB - MDPI CY - Basel ER - TY - JOUR A1 - Engelmann, Ulrich M. A1 - Seifert, Julian A1 - Mues, Benedikt A1 - Roitsch, Stefan A1 - Ménager, Christine A1 - Schmidt, Annette M. A1 - Slabu, Ioana T1 - Heating efficiency of magnetic nanoparticles decreases with gradual immobilization in hydrogels JF - Journal of Magnetism and Magnetic Materials Y1 - 2019 U6 - https://doi.org/10.1016/j.jmmm.2018.09.113 SN - 0304-8853 VL - 471 IS - 1 SP - 486 EP - 494 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Engelmann, Ulrich M. A1 - Roeth, Anjali A.J. A1 - Eberbeck, Dietmar A1 - Buhl, Eva Miriam A1 - Neumann, Ulf Peter A1 - Schmitz-Rode, Thomas A1 - Slabu, Ioana T1 - Combining Bulk Temperature and Nanoheating Enables Advanced Magnetic Fluid Hyperthermia Efficacy on Pancreatic Tumor Cells JF - Scientific Reports N2 - Many efforts are made worldwide to establish magnetic fluid hyperthermia (MFH) as a treatment for organ-confined tumors. However, translation to clinical application hardly succeeds as it still lacks of understanding the mechanisms determining MFH cytotoxic effects. Here, we investigate the intracellular MFH efficacy with respect to different parameters and assess the intracellular cytotoxic effects in detail. For this, MiaPaCa-2 human pancreatic tumor cells and L929 murine fibroblasts were loaded with iron-oxide magnetic nanoparticles (MNP) and exposed to MFH for either 30 min or 90 min. The resulting cytotoxic effects were assessed via clonogenic assay. Our results demonstrate that cell damage depends not only on the obvious parameters bulk temperature and duration of treatment, but most importantly on cell type and thermal energy deposited per cell during MFH treatment. Tumor cell death of 95% was achieved by depositing an intracellular total thermal energy with about 50% margin to damage of healthy cells. This is attributed to combined intracellular nanoheating and extracellular bulk heating. Tumor cell damage of up to 86% was observed for MFH treatment without perceptible bulk temperature rise. Effective heating decreased by up to 65% after MNP were internalized inside cells. Y1 - 2018 U6 - https://doi.org/10.1038/s41598-018-31553-9 SN - 2045-2322 VL - 8 IS - 1 SP - Article number 13210 PB - Springer Nature CY - Cham ER - TY - JOUR A1 - Engelmann, Ulrich M. A1 - Pourshahidi, Mohammad Ali A1 - Shalaby, Ahmed A1 - Krause, Hans-Joachim T1 - Probing particle size dependency of frequency mixing magnetic detection with dynamic relaxation simulation JF - Journal of Magnetism and Magnetic Materials N2 - Biomedical applications of magnetic nanoparticles (MNP) fundamentally rely on the particles’ magnetic relaxation as a response to an alternating magnetic field. The magnetic relaxation complexly depends on the interplay of MNP magnetic and physical properties with the applied field parameters. It is commonly accepted that particle core size is a major contributor to signal generation in all the above applications, however, most MNP samples comprise broad distribution spanning nm and more. Therefore, precise knowledge of the exact contribution of individual core sizes to signal generation is desired for optimal MNP design generally for each application. Specifically, we present a magnetic relaxation simulation-driven analysis of experimental frequency mixing magnetic detection (FMMD) for biosensing to quantify the contributions of individual core size fractions towards signal generation. Applying our method to two different experimental MNP systems, we found the most dominant contributions from approx. 20 nm sized particles in the two independent MNP systems. Additional comparison between freely suspended and immobilized MNP also reveals insight in the MNP microstructure, allowing to use FMMD for MNP characterization, as well as to further fine-tune its applicability in biosensing. Y1 - 2022 U6 - https://doi.org/10.1016/j.jmmm.2022.169965 SN - 0304-8853 VL - 563 IS - In progress, Art. No. 169965 PB - Elsevier CY - Amsterdam ER -