TY - JOUR A1 - Schmitz, Philipp A1 - Weber, Martin T1 - Buying and selling behavior of individual investors in option-like securities Y1 - 2007 SP - 1 EP - 36 ER - TY - JOUR A1 - Ribitsch, D. A1 - Karl, W. A1 - Birner-Gruenberger, R. A1 - Gruber, K. A1 - Eiteljoerg, I. A1 - Remler, P. A1 - Wieland, S. A1 - Siegert, Petra A1 - Maurer, Karl-Heinz A1 - Schwab, H. T1 - C-terminal truncation of a metagenome-derived detergent protease for effective expression in E. coli JF - Journal of biotechnology N2 - Recently, a new alkaline protease named HP70 showing highest homology to extracellular serine proteases of Stenotrophomonas maltophilia and Xanthomonas campestris was found in the course of a metagenome screening for detergent proteases (Niehaus et al., submitted for publication). Attempts to efficiently express the enzyme in common expression hosts had failed. This study reports on the realization of overexpression in Escherichia coli after structural modification of HP70. Modelling of HP70 resulted in a two-domain structure, comprising the catalytic domain and a C-terminal domain which includes about 100 amino acids. On the basis of the modelled structure the enzyme was truncated by deletion of most of the C-terminal domain yielding HP70-C477. This structural modification allowed effective expression of active enzyme using E. coli BL21-Gold as the host. Specific activity of HP70-C477 determined with suc-l-Ala-l-Ala-l-Pro-l-Phe-p-nitroanilide as the substrate was 30 ± 5 U/mg compared to 8 ± 1 U/mg of the native enzyme. HP70-C477 was most active at 40 °C and pH 7–11; these conditions are prerequisite for a potential application as detergent enzyme. Determination of kinetic parameters at 40 °C and pH = 9.5 resulted in KM = 0.23 ± 0.01 mM and kcat = 167.5 ± 3.6 s⁻¹. MS-analysis of peptide fragments obtained from incubation of HP70 and HP70-C477 with insulin B indicated that the C-terminal domain influences the cleavage preferences of the enzyme. Washing experiments confirmed the high potential of HP70-C477 as detergent protease. Y1 - 2010 U6 - http://dx.doi.org/10.1016/j.jbiotec.2010.09.947 SN - 1873-4863 (E-Journal); 0168-1656 (Print) VL - 150 IS - 3 SP - 408 EP - 416 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schiffer, Stefan A1 - Ferrein, Alexander A1 - Lakemeyer, Gerhard T1 - Caesar: an intelligent domestic service robot JF - Intelligent service robotics N2 - In this paper we present CAESAR, an intelligent domestic service robot. In domestic settings for service robots complex tasks have to be accomplished. Those tasks benefit from deliberation, from robust action execution and from flexible methods for human–robot interaction that account for qualitative notions used in natural language as well as human fallibility. Our robot CAESAR deploys AI techniques on several levels of its system architecture. On the low-level side, system modules for localization or navigation make, for instance, use of path-planning methods, heuristic search, and Bayesian filters. For face recognition and human–machine interaction, random trees and well-known methods from natural language processing are deployed. For deliberation, we use the robot programming and plan language READYLOG, which was developed for the high-level control of agents and robots; it allows combining programming the behaviour using planning to find a course of action. READYLOG is a variant of the robot programming language Golog. We extended READYLOG to be able to cope with qualitative notions of space frequently used by humans, such as “near” and “far”. This facilitates human–robot interaction by bridging the gap between human natural language and the numerical values needed by the robot. Further, we use READYLOG to increase the flexible interpretation of human commands with decision-theoretic planning. We give an overview of the different methods deployed in CAESAR and show the applicability of a system equipped with these AI techniques in domestic service robotics Y1 - 2012 U6 - http://dx.doi.org/10.1007/s11370-012-0118-y SN - 1861-2776 N1 - Special Issue on Artificial Intelligence Techniques for Robotics: Sensing, Representation and Action, Part I VL - 5 IS - 4 SP - 259 EP - 276 PB - Springer CY - Berlin ER - TY - JOUR A1 - Kern, Alexander A1 - Schelthoff, Christof A1 - Mathieu, Moritz T1 - Calculation of interception efficiencies for airterminations using a dynamic electro-geometrical model Y1 - 2011 N1 - XI International Symposium on Lightning Protection (SIPDA), Fortaleza (Brasilien), 2011. SP - 1 EP - 6 PB - IEEE CY - New York ER - TY - JOUR A1 - Birgel, Stefan A1 - Leschinger, Tim A1 - Wegmann, Kilian A1 - Staat, Manfred T1 - Calculation of muscle forces and joint reaction loads in the shoulder area via an OpenSim based computer model JF - tm - Technisches Messen N2 - Using the OpenSim software and verified anatomical data, a computer model for the calculation of biomechanical parameters is developed and used to determine the effect of a reattachment of the Supraspinatus muscle with a medial displacement of the muscle attachment point, which may be necessary for a rupture of the supraspinatus tendon. The results include the influence of the operation on basic biomechanical parameters such as the lever arm, as well as the calculated the muscle activations for the supraspinatus and deltoid. In addition, the influence on joint stability is examined by an analysis of the joint reaction force. The study provides a detailed description of the used model, as well as medical findings to a reattachment of the supraspinatus. Mit der Software OpenSim und überprüften anatomischen Daten wird ein Computermodell zur Berechnung von biomechanischen Parametern entwickelt und genutzt, um den Effekt einer Refixierung des Supraspinatusmuskels mit einer medialen Verschiebung des Muskelansatzpunktes zu ermitteln, wie sie unter anderem nach einem Riss der Supraspinatussehne notwendig sein kann. Die Ergebnisse umfassen hierbei den Einfluss der Operation auf grundlegende biomechanische Parameter wie den Hebelarm sowie die berechneten Muskelaktivierungen für den Supraspinatus und Deltoideus. Zusätzlich wird der Einfluss auf die Gelenkstabilität betrachtet und durch eine Analyse der Gelenkreaktionskraft untersucht. Die Studie bietet eine detaillierte Beschreibung des genutzten Modells, sowie medizinische Erkenntnisse zu einer Refixierung des Supraspinatus. Y1 - 2018 U6 - http://dx.doi.org/10.1515/teme-2017-0114 SN - 2196-7113 VL - 85 IS - 5 SP - 321 EP - 330 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Kern, Alexander A1 - Wiesinger, J. A1 - Zischank, Wolfgang J. T1 - Calculation of the longitudinal voltage along metal tubes caused by lightning currents and protection measures JF - Seventh International Symposium on High Voltage Engineering : Dresden, August 26 - 30 1991 Y1 - 1991 N1 - International Symposium on High Voltage Engineering <7, 1991, Dresden> PB - Techn. Univ. CY - Dresden ER - TY - JOUR A1 - Grotendorst, Johannes A1 - Shuang-Ren, Zhao A1 - Halling, Horst T1 - Calculation of the Potential Distribution for a Three-Layer Spherical Volume Conductor / Shuang-Ren, Zhao ; Grotendorst, Johannes ; Halling, Horst JF - MapleTech . 2 (1996), H. 1 Y1 - 1996 SN - 1061-5733 N1 - zugl. Technical Report KFA-ZAM-IB-9511 ; The Maple Technical Newsletters SP - 59 EP - 66 ER - TY - JOUR A1 - Schäfer, Horst T1 - Calculation of the surface stray field and the demagnetizing field of a g.o. 3% SiFe sheet caused by a misoriented grain JF - Physica Scripta. 39 (1989), H. 4 Y1 - 1989 SN - 0031-8949 SP - 531 EP - 534 ER - TY - JOUR A1 - Heuermann, Holger T1 - Calibration of a Network Analyzer Without a Thru Connection for Nonlinear and Multiport Measurements JF - IEEE Transactions on Microwave Theory and Techniques. 56 (2008), H. 11, 1 Y1 - 2008 SN - 0018-9480 SP - 2505 EP - 2510 ER - TY - JOUR A1 - Claer, Mario A1 - Ferrein, Alexander A1 - Schiffer, Stefan T1 - Calibration of a Rotating or Revolving Platform with a LiDAR Sensor JF - Applied Sciences Y1 - 2019 U6 - http://dx.doi.org/10.3390/app9112238 SN - 2076-3417 VL - Volume 9 IS - issue 11, 2238 PB - MDPI CY - Basel ER - TY - JOUR A1 - Heuermann, Holger A1 - Schiek, Burkhard T1 - Calibration of network analyser measurements with leakage errors JF - Electronics letters. 30 (1994), H. 1 Y1 - 1994 SN - 0013-5194 SP - 52 EP - 53 ER - TY - JOUR A1 - Helsper, Christoph A1 - Fißan, H. J. A1 - Kasper, W. T1 - Calibration of Optical Particle Counters with Respect to Particle Size / Fißan, H. J. ; Helsper, C.; Kasper, W. JF - Particle and Particle Systems Characterization. 1 (1984), H. 1984 Y1 - 1984 SN - 1521-4117 SP - 108 EP - 111 ER - TY - JOUR A1 - Helsper, Christoph A1 - Fißan, H. J. T1 - Calibration of the Polytec HC-15 and HC-70 Optical Particle Counters / Fißan, H. J. ; Helsper, C. JF - Aerosols in the mining and industrial work environments, Vol. 3. Instrumentation, Marple, Virgil A. ; Liu, Benjamin Y. Y1 - 1983 N1 - International Symposium on Aerosols in the Mining and Industrial Work Environment ; (1981.11.01-06 : ; Minneapolis/Minn.) SP - 825 EP - 829 PB - Ann Arbor Science CY - Ann Arbor, Mich. ER - TY - JOUR A1 - Heuermann, Holger T1 - Calibration procedures with series impedances and unknown lines simplify on-wafer measurements JF - IEEE transactions on microwave theory and techniques : MTT ; a publication of the IEEE Microwave Theory and Techniques Society. 47 (1999), H. 1 Y1 - 1999 SN - 0018-9480 SP - 1 EP - 5 ER - TY - JOUR A1 - Belavy, Daniel L. A1 - Albracht, Kirsten A1 - Bruggemann, Gert-Peter A1 - Vergroesen, Pieter-Paul A. A1 - Dieen, Jaap H. van T1 - Can exercise positively influence the intervertebral disc? JF - Sports Medicine N2 - To better understand what kinds of sports and exercise could be beneficial for the intervertebral disc (IVD), we performed a review to synthesise the literature on IVD adaptation with loading and exercise. The state of the literature did not permit a systematic review; therefore, we performed a narrative review. The majority of the available data come from cell or whole-disc loading models and animal exercise models. However, some studies have examined the impact of specific sports on IVD degeneration in humans and acute exercise on disc size. Based on the data available in the literature, loading types that are likely beneficial to the IVD are dynamic, axial, at slow to moderate movement speeds, and of a magnitude experienced in walking and jogging. Static loading, torsional loading, flexion with compression, rapid loading, high-impact loading and explosive tasks are likely detrimental for the IVD. Reduced physical activity and disuse appear to be detrimental for the IVD. We also consider the impact of genetics and the likelihood of a ‘critical period’ for the effect of exercise in IVD development. The current review summarises the literature to increase awareness amongst exercise, rehabilitation and ergonomic professionals regarding IVD health and provides recommendations on future directions in research. KW - Intradiscal Pressure KW - Annulus Fibrosus KW - Disc Degeneration KW - Nucleus Pulposus KW - Intervertebral Disc Y1 - 2016 U6 - http://dx.doi.org/10.1007/s40279-015-0444-2 SN - 1179-2035 VL - 46 IS - 4 SP - 473 EP - 485 PB - Springer CY - Berlin ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Mourzina, Y. G. A1 - Schubert, J. A1 - Zander, W. A1 - Legin, A. A1 - Vlasov, Y. G. A1 - Lüth, H. T1 - Can pulsed laser deposition serve as an advanced technique in fabricating chemical sensors? JF - Sensors and Actuators B. 78 (2001), H. 1-3 Y1 - 2001 SN - 0925-4005 N1 - Selected Papers form Eurosensors XIV SP - 273 EP - 278 ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Mourzina, Y. G. A1 - Schubert, J. A1 - Zander, W. A1 - Legin, A. A1 - Vlasov, Y. G. A1 - Lüth, H. T1 - Can pulsed laser deposition serve as an advanced technique in fabricating chemical sensors? JF - Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...] Y1 - 2000 SN - 87-89935-50-0 N1 - Eurosensors ; (14, 2000, København) ; Eurosensors ; (14 : ; 2000.08.27-30 : ; Copenhagen) ; European Conference on Solid-State Transducers ; (14 : ; 2000.08.27-30 : ; Copenhagen) SP - 615 EP - 618 PB - MIC, Mikroelektronik Centret CY - Lyngby, Denmark ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Lanzl, Ines M. T1 - Can vascular function be assessed by the interpretation of retinal vascular diameter changes? JF - Investigative Ophthalmology & Visual Science, IOVS. 52 (2011), H. 1 Y1 - 2011 SN - 0146-0404 SP - 635 EP - 636 PB - ARVO CY - Rockville, Md. ER - TY - JOUR A1 - Temiz Artmann, Aysegül A1 - Yalcin, Ozlem A1 - Resmi, Halil A1 - Baskurt, Oguz K. T1 - Can white blood cell activation be one of the major factors that affect hemorheological parameters during and after exercise? JF - Clinical Hemorheology and Microcirculation. 26 (2002), H. 3 Y1 - 2002 SN - 1386-0291 N1 - = The 11th European Symposium on Clinical Hemorheology, Rouen, France, 19-22 September 2000 SP - 189 EP - 193 ER - TY - JOUR A1 - Jan Thimo, Grundmann A1 - Bauer, Waldemar A1 - Biele, Jens A1 - Boden, Ralf A1 - Ceriotti, Matteo A1 - Cordero, Federico A1 - Dachwald, Bernd A1 - Dumont, Etienne A1 - Grimm, Christian D. A1 - Hercik, David T1 - Capabilities of Gossamer-1 derived small spacecraft solar sails carrying Mascot-derived nanolanders for in-situ surveying of NEAs JF - Acta Astronautica Y1 - 2019 U6 - http://dx.doi.org/10.1016/j.actaastro.2018.03.019 SN - 0094-5765 VL - 156 IS - 3 SP - 330 EP - 362 PB - Elsevier CY - Amsterdam ER -