TY  - GEN
A1  - Jansen, Sebastian
A1  - Behbahani, Mehdi
A1  - Laumen, Marco
A1  - Kaufmann, Tim
A1  - Hormes, Marcus
A1  - Schmitz-Rode, Thomas
A1  - Behr, Marek
A1  - Steinseifer, Ulrich
T1  - 3D stereo-PIV validation for CFD-simulation of steady flow through the human aorta using rapid-prototyping techniques
Y1  - 2010
N1  - MPF2010, IV International Symposium on Modelling of Physiological Flows, Sardinia, Italy, June 02-05, 2010
ER  - 
TY  - CHAP
A1  - Gerhards, Michael
A1  - Belloum, Adam
A1  - Berretz, Frank
A1  - Sander, Volker
A1  - Skorupa, Sascha
T1  - A history-tracing XML-based provenance framework for workflows
T2  - The 5th Workshop on Workflows in Support of Large-Scale Science
N2  - The importance of validating and reproducing the outcome of computational processes is fundamental to many application domains. Assuring the provenance of workflows will likely become even more important with respect to the incorporation of human tasks to standard workflows by emerging standards such as WS-HumanTask. This paper addresses this trend by an actor-based workflow approach that actively support provenance. It proposes a framework to track and store provenance information automatically that applies for various workflow management systems. In particular, the introduced provenance framework supports the documentation of workflows in a legally binding way. The authors therefore use the concept of layered XML documents, i.e. history-tracing XML. Furthermore, the proposed provenance framework enables the executors (actors) of a particular workflow task to attest their operations and the associated results by integrating digital XML signatures.
KW  - workflow
KW  - provenance
KW  - framework
KW  - containers
KW  - humans
KW  - synchronization
KW  - libraries
KW  - history
KW  - concrete
KW  - XML
Y1  - 2010
SN  - 978-1-4244-8989-3
U6  - https://doi.org/10.1109/WORKS.2010.5671873
N1  - The 5th Workshop on Workflows in Support of Large-Scale Science, 14 Nov. 2010, New Orleans, USA
PB  - IEEE
CY  - New York
ER  - 
TY  - CHAP
A1  - Nguyen, N.-H.
A1  - Raatschen, Hans-Jürgen
A1  - Staat, Manfred
T1  - A hyperelastic model of biological tissue materials in tubular organs
Y1  - 2010
N1  - 4th European Conference on Computational Mechanics (Solids, Structures and Coupled Problems in Engineering), ECCOMAS ECCM 2010, Paris, France, May 17 – 21, 2010
ER  - 
TY  - JOUR
A1  - Grottke, O.
A1  - Braunschweig, T.
A1  - Philippen, B.
A1  - Gatzweiler, Karl-Heinz
A1  - Gronloh, N.
A1  - Staat, Manfred
A1  - Rossaint, R.
A1  - Tolba, R.
T1  - A new model for blunt liver injuries in the swine
JF  - European Surgical Research
N2  - Background: To elaborate the impact of new haemostatic agents we developed an instrument for the pressure-controlled induction of blunt liver injuries in a porcine animal model. Materials and Methods: A dilutional coagulopathy of 80% of animal blood volume was induced in 9 anaesthetized pigs. Animals were randomly assigned to be injured with a force of 112 Newton (N) (n = 1), 224 ± 19 N (n = 4) or 355 ± 35 N (n = 4). The impact of injury was measured by blood loss, survival time and coagulation parameters. Liver histology was obtained to evaluate the degree of liver injury. Results: The profound haemodilution resulted in a significant alteration of all coagulation parameters. After inflicting the injury with 355 ± 35 N, both the survival time (30 ± 9 min; p = 0.006) and blood loss (68 ± 16 ml min–1, p = 0.002) were significantly different as compared to injuries with 224 ± 19 N (survival time: 76 ± 20 min, blood loss: 23 ± 4 ml min–1). In contrast, an injury with 112 N led to an insignificant blood loss of only 239 ml. Conclusion: We developed a pressure-controlled clamp that allows for the induction of blunt liver traumas with highly reproducible injuries with a positive correlation with blood loss and survival.
Y1  - 2010
U6  - https://doi.org/10.1159/000265053
SN  - 1421-9921
VL  - 44
IS  - 2
SP  - 65
EP  - 73
PB  - Karger
CY  - Basel
ER  - 
TY  - JOUR
A1  - Hirschfeld, Julian A.
A1  - Lustfeld, Hans
A1  - Reißel, Martin
A1  - Steffen, Bernhard
T1  - A novel scheme for precise diagnostics and effective stabilization of currents in a fuel cell stack
JF  - International Journal of Energy Research
N2  - A novel scheme for detecting inhomogeneous internal currents in a fuel cell stack is presented. In this paper the scheme is investigated for the case that the flow field plates consist of graphite. Then plates of high conductivity, e.g. aluminium between the flow field plates together with small slits in these plates have three effects: (a) Whenever a local inhomogeneity of the electric current occurs at a particular cell in the stack, this will induce a surface current close to that cell perpendicular to the averaged current. This current can be detected. (b) The plates of high conductivity completely prevent the inhomogeneities from spreading to neighbouring cells. (c) Even at the particular cell the inhomogeneity is suppressed as far as possible. Thus this scheme leads to much better diagnostic possibilities and at the same time reduces electric instabilities to an extent, where they probably become harmless. This scheme will first be explained for a simple model to clarify the idea. However, very precise three dimensional computations using realistic parameters are presented, corroborating the results of the simple model.
Y1  - 2010
U6  - https://doi.org/10.1002/er.1662
SN  - 0363-907X
VL  - 34
IS  - 3
SP  - 293
EP  - 301
PB  - Wiley
CY  - London
ER  - 
TY  - CHAP
A1  - Pham, Phu Tinh
A1  - Vu, Khoi Duc
A1  - Tran, Thanh Ngoc
A1  - Staat, Manfred
T1  - A primal-dual algorithm for shakedown analysis of elastic-plastic bounded linearly kinematic hardening bodies
Y1  - 2010
N1  - 4th European Conference on Computational Mechanics (Solids, Structures and Coupled Problems in Engineering), ECCOMAS ECCM 2010, Paris, France, May 17 – 21, 2010
ER  - 
TY  - JOUR
A1  - Kozhalakova, A. A.
A1  - Zhubanova, Azhar A.
A1  - Mansurov, Z. A.
A1  - Digel, Ilya
A1  - Tazhibayeva, S. M.
A1  - Artmann, Gerhard
A1  - Temiz Artmann, Aysegül
T1  - Adsorption of bacterial lipopolysaccharides on carbonized rice shell
JF  - Science of Central Asia
Y1  - 2010
SP  - 50
EP  - 54
ER  - 
TY  - JOUR
A1  - Siqueira, José R. Jr.
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Zucolotto, Valtencir
A1  - Oliveira, Osvaldo N. Jr.
A1  - Schöning, Michael Josef
T1  - Associating biosensing properties with the morphological structure of multilayers containing carbon nanotubes on field-effect devices
JF  - Physica Status Solidi (A)
N2  - The control of molecular architecture provided by the layer-by-layer (LbL) technique has led to enhanced biosensors, in which advantageous features of distinct materials can be combined. Full optimization of biosensing performance, however, is only reached if the film morphology is suitable for the principle of detection of a specific biosensor. In this paper, we report a detailed morphology analysis of LbL films made with alternating layers of single-walled carbon nanotubes (SWNTs) and polyamidoamine (PAMAM) dendrimers, which were then covered with a layer of penicillinase (PEN). An optimized performance to detect penicillin G was obtained with 6-bilayer SWNT/PAMAM LbL films deposited on p-Si-SiO2-Ta2O5 chips, used in biosensors based on a capacitive electrolyte-insulator-semiconductor (EIS) and a light-addressable potentiometric sensor (LAPS) structure, respectively. Field-emission scanning electron microscopy (FESEM) and atomic force microscopy (AFM) images indicated that the LbL films were porous, with a large surface area due to interconnection of SWNT into PAMAM layers. This morphology was instrumental for the adsorption of a larger quantity of PEN, with the resulting LbL film being highly stable. The experiments to detect penicillin were performed with constant-capacitance (ConCap) and constant-current (CC) measurements for EIS and LAPS sensors, respectively, which revealed an enhanced detection signal and sensitivity of ca. 100 mV/decade for the field-effect sensors modified with the PAMAM/SWNT LbL film. It is concluded that controlling film morphology is essential for an enhanced performance of biosensors, not only in terms of sensitivity but also stability and response time.
Y1  - 2010
U6  - https://doi.org/10.1002/pssa.200983301
SN  - 1862-6300
N1  - Special Issue: Engineering of Functional Interfaces EnFI 2009
VL  - 207
IS  - 4
SP  - 781
EP  - 786
PB  - Wiley-VCH
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Abouzar, Maryam H.
A1  - Poghossian, Arshak
A1  - Siqueira, José R. Jr.
A1  - Oliveira, Osvaldo N. Jr.
A1  - Moritz, Werner
A1  - Schöning, Michael Josef
T1  - Capacitive electrolyte-insulator-semiconductor structures functionalised with a polyelectrolyte/enzyme multilayer: New strategy for enhanced field-effect biosensing
JF  - Physica Status Solidi (A)
N2  - A novel strategy for enhanced field-effect biosensing using capacitive electrolyte–insulator–semiconductor (EIS) structures functionalised with pH-responsive weak polyelectrolyte/enzyme or dendrimer/enzyme multilayers is presented. The feasibility of the proposed approach is exemplarily demonstrated by realising a penicillin biosensor based on a capacitive p-Si–SiO2 EIS structure functionalised with a poly(allylamine hydrochloride) (PAH)/penicillinase and a poly(amidoamine) dendrimer/penicillinase multilayer. The developed sensors response to changes in both the local pH value near the gate surface and the charge of macromolecules induced via enzymatic reaction, resulting in a higher sensitivity. For comparison, an EIS penicillin biosensor with adsorptively immobilised penicillinase has been also studied. The highest penicillin sensitivity of 100 mV/dec has been observed for the EIS sensor functionalised with the PAH/penicillinase multilayer. The lower and upper detection limit was around 20 µM and 10 mM, respectively. In addition, an incorporation of enzymes in a multilayer prepared by layer-by-layer technique provides a larger amount of immobilised enzymes per sensor area, reduces enzyme leaching effects and thus, enhances the biosensor lifetime (the loss of penicillin sensitivity after 2 months was 10–12%).
Y1  - 2010
U6  - https://doi.org/10.1002/pssa.200983317
SN  - 1862-6300
N1  - Special Issue: Engineering of Functional Interfaces EnFI 2009
VL  - 207
IS  - 4
SP  - 884
EP  - 890
PB  - Wiley-VCH
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Abouzar, Maryam H.
A1  - Wenmackers, Sylvia
A1  - Janssens, Stoffel D.
A1  - Haenen, Ken
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Capacitive field-effect (bio-)chemical sensors based on nanocrystalline diamond films
JF  - MRS Online Proceedings Library
N2  - Capacitive field-effect electrolyte-diamond-insulator-semiconductor (EDIS) structures with O-terminated nanocrystalline diamond (NCD) as sensitive gate material have been realized and investigated for the detection of pH, penicillin concentration, and layer-by-layer adsorption of polyelectrolytes. The surface oxidizing procedure of NCD thin films as well as the seeding and NCD growth process on a Si-SiO2 substrate have been improved to provide high pH-sensitive, non-porous thin films without damage of the underlying SiO2 layer and with a high coverage of O-terminated sites. The NCD surface topography, roughness, and coverage of the surface groups have been characterized by SEM, AFM and XPS methods. The EDIS sensors with O-terminated NCD film treated in oxidizing boiling mixture for 45 min show a pH sensitivity of about 50 mV/pH. The pH-sensitive properties of the NCD have been used to develop an EDIS-based penicillin biosensor with high sensitivity (65-70 mV/decade in the concentration range of 0.25-2.5 mM penicillin G) and low detection limit (5 μM). The results of label-free electrical detection of layer-by-layer adsorption of charged polyelectrolytes are presented, too.
Y1  - 2010
SN  - 1946-4274
VL  - 1203
PB  - MRS
CY  - Warrendale
ER  - 
TY  - JOUR
A1  - Kurz, R.
A1  - Linder, Peter
A1  - Trzewik, Jürgen
A1  - Rüffer, M.
A1  - Artmann, Gerhard
A1  - Digel, Ilya
A1  - Rothermel, A.
A1  - Robitzki, A.
A1  - Temiz Artmann, Aysegül
T1  - Contractile tension and beating rates of self-exciting monolayers and 3D-tissue constructs of neonatal rat cardiomyocytes
JF  - Medical and Biological Engineering and Computing
N2  - The CellDrum technology (The term 'CellDrum technology' includes a couple of slightly different technological setups for measuring lateral mechanical tension in various types of cell monolayers or 3D-tissue constructs) was designed to quantify the contraction rate and mechanical tension of self-exciting cardiac myocytes. Cells were grown either within flexible, circular collagen gels or as monolayer on top of respective 1-mum thin silicone membranes. Membrane and cells were bulged outwards by air pressure. This biaxial strain distribution is rather similar the beating, blood-filled heart. The setup allowed presetting the mechanical residual stress level externally by adjusting the centre deflection, thus, mimicking hypertension in vitro. Tension was measured as oscillating differential pressure change between chamber and environment. A 0.5-mm thick collagen-cardiac myocyte tissue construct induced after 2 days of culturing (initial cell density 2 x 10(4) cells/ml), a mechanical tension of 1.62 +/- 0.17 microN/mm(2). Mechanical load is an important growth regulator in the developing heart, and the orientation and alignment of cardiomyocytes is stress sensitive. Therefore, it was necessary to develop the CellDrum technology with its biaxial stress-strain distribution and defined mechanical boundary conditions. Cells were exposed to strain in two directions, radially and circumferentially, which is similar to biaxial loading in real heart tissues. Thus, from a biomechanical point of view, the system is preferable to previous setups based on uniaxial stretching.
Y1  - 2010
U6  - https://doi.org/10.1007/s11517-009-0552-y
SN  - 1741-0444
VL  - 48
IS  - 1
SP  - 59
EP  - 65
PB  - Springer Nature
CY  - Cham
ER  - 
TY  - JOUR
A1  - Beer, S.
A1  - Streun, M.
A1  - Hombach, T.
A1  - Buehler, J.
A1  - Jahnke, S.
A1  - Khodaverdi, M.
A1  - Larue, H.
A1  - Minwuyelet, S.
A1  - Parl, C.
A1  - Roeb, G.
A1  - Schurr, U.
A1  - Ziemons, Karl
T1  - Design and initial performance of PlanTIS: a high-resolution positron emission tomograph for plants
JF  - Physics in Medicine and Biology
N2  - Positron emitters such as 11C, 13N and 18F and their labelled compounds are widely used in clinical diagnosis and animal studies, but can also be used to study metabolic and physiological functions in plants dynamically and in vivo. A very particular tracer molecule is 11CO2 since it can be applied to a leaf as a gas. We have developed a Plant Tomographic Imaging System (PlanTIS), a high-resolution PET scanner for plant studies. Detectors, front-end electronics and data acquisition architecture of the scanner are based on the ClearPET™ system. The detectors consist of LSO and LuYAP crystals in phoswich configuration which are coupled to position-sensitive photomultiplier tubes. Signals are continuously sampled by free running ADCs, and data are stored in a list mode format. The detectors are arranged in a horizontal plane to allow the plants to be measured in the natural upright position. Two groups of four detector modules stand face-to-face and rotate around the field-of-view. This special system geometry requires dedicated image reconstruction and normalization procedures. We present the initial performance of the detector system and first phantom and plant measurements.
Y1  - 2010
U6  - https://doi.org/10.1088/0031-9155/55/3/006
SN  - 1361-6560
VL  - 55
IS  - 3
SP  - 635
EP  - 646
PB  - IOP
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Reisert, Steffen
A1  - Henkel, Hartmut
A1  - Schneider, Andreas
A1  - Schäfer, Daniel
A1  - Friedrich, Peter
A1  - Berger, Jörg
A1  - Schöning, Michael Josef
T1  - Development of a handheld sensor system for the online measurement of hydrogen peroxide in aseptic filling systems
JF  - Physica Status Solidi (A)
N2  - A handheld sensor system for the online measurement of hydrogen peroxide (H2O2) in aseptic sterilisation processes has been developed. It is based on a calorimetric-type gas sensor that consists of a differential set-up of two temperature sensors, of which one is catalytically activated and the second one is passivated and used as reference. The sensor principle relies in detecting a rise in temperature on the active sensor due to the exothermic reaction of H2O2 on the catalytic surface. To characterise the sensor system towards H2O2 sensitivity and other influencing factors, measurements have been carried out both at an experimental set-up and a manufacturer's sterilisation machine. Physical sensor characterisation was done by means of the optical microscopy.
Y1  - 2010
U6  - https://doi.org/10.1002/pssa.200983304
SN  - 1862-6300
N1  - Special Issue: Engineering of Functional Interfaces EnFI 2009
VL  - 207
IS  - 4
SP  - 913
EP  - 918
PB  - Wiley-VCH
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Spelthahn, Heiko
A1  - Schaffrath, Sophie
A1  - Coppe, Thomas
A1  - Rufi, Frederic
A1  - Schöning, Michael Josef
T1  - Development of an electrolyte-insulator-semiconductor (EIS) based capacitive heavy metal sensor for the detection of Pb2+ und Cd2+ ions
JF  - Physica status solidi (a) : applications and material science
N2  - Chalcogenide glass materials as membranes for potentiometric sensors for chemical analysis in solutions have been studied since more than 20 years. In this work, an electrolyte–insulator–semiconductor structure was combined with chalcogenide glass membranes prepared by means of the pulsed laser deposition technique. Depending on the membrane composition a selectivity to different ions (Cd2+ and Pb2+) is achieved. The different sensor membranes have been physically characterised using microscopy, ellipsometry, profilometry, atomic force microscopy (AFM), scanning electron microscopy (SEM) and Rutherford backscattering spectrometry (RBS). The electrochemical behaviour has been investigated via capacitance/voltage (C/V) and constant capacitance (ConCap) measurements and results in a Cd2+ sensitivity of 23.1 ± 0.6 mV per decade in a linear range from 7 × 10−6 to 10−2 mol/l and 24.4 ± 0.5 mV per decade in a linear range from 5 × 10−6 to 10−2 mol/l for Pb2+, respectively.
Y1  - 2010
U6  - https://doi.org/10.1002/pssa.200983306
SN  - 1862-6300
N1  - Special Issue: Engineering of Functional Interfaces EnFI 2009
VL  - 207
IS  - 4
SP  - 930
EP  - 934
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Heinzel, Alexander
A1  - Schäfer, Ralf
A1  - Müller, Hans-Wilhelm
A1  - Schieffer, Andre
A1  - Ingenhag, Ariane
A1  - Northoff, Georg
A1  - Franz, Matthias
A1  - Hautzel, Hubertus
T1  - Differential modulation of valence and arousal in high-alexithymic and low-alexithymic individuals
JF  - Neuroreport
N2  - High-alexithymic individuals are characterized by an impaired ability to identify and communicate emotions whereas low-alexithymic individuals have a wide-ranging ability to deal with emotions. This study examined the hypothesis that valence and arousal modifications of emotional stimuli differentially modulate cortical regions in high-alexithymic and low-alexithymic individuals. To this end, 28 high-alexithymic and 25 low-alexithymic individuals were investigated with event-related fMRI using visual emotional stimuli. We found differential neural activations in the dorsal anterior cingulate, the insula and the amygdala. We suggest that these differences may account for the impaired ability of high-alexithymic individuals to appropriately handle emotional stimuli.
Y1  - 2010
U6  - https://doi.org/10.1097/WNR.0b013e32833f38e0
SN  - 1473-558X
VL  - 21
IS  - 15
SP  - 998
EP  - 1002
PB  - Lippincott Williams & Wilkins
CY  - London
ER  - 
TY  - CHAP
A1  - Lehnertz, Klaus
A1  - Bialonski, Stephan
A1  - Horstmann, Marie-Therese
A1  - Krug, Dieter
A1  - Rothkegel, Alexander
A1  - Staniek, Matthäus
A1  - Wagner, Tobias
T1  - Epilepsy
T2  - Reviews of Nonlinear Dynamics and Complexity, Volume 2
Y1  - 2010
SN  - 9783527628001
U6  - https://doi.org/10.1002/9783527628001.ch5
SP  - 159
EP  - 200
PB  - Wiley-VCH
ER  - 
TY  - CHAP
A1  - Staat, Manfred
A1  - Sponagel, Stefan
A1  - Nguyen, Nhu Huynh
T1  - Experiment and material model for soft tissue materials
T2  - Constitutive  models for rubber VI
N2  - Biomechanics studies biological soft tissue materials (growth, remodeling) in vivo. For this objective, the detailed information of material properties must be well defined to construct reliable constitutive models. In the paper, the bulge test is carried out with elastomers in order to develop a test method. Then, application of the test for soft tissue materials is straightforward due to the similarities between elastomers with soft tissue materials as proved in Holzapfel 2005, Ogden 2009. It means, after the preliminary experiments and parameter identification with rubber materials has been setup, experiments on soft tissue materials can be similarly carried out. Elastomers have a complex behavior which strongly depends on the largest previous load cycle. For simplicity we consider only the first loading.
Y1  - 2010
SN  - 9780429206597 (eBook)
U6  - https://doi.org/10.1201/NOE0415563277-90
PB  - Taylor & Francis
CY  - London
ER  - 
TY  - JOUR
A1  - Leimena, W.
A1  - Artmann, Gerhard
A1  - Dachwald, Bernd
A1  - Temiz Artmann, Aysegül
A1  - Gossmann, Matthias
A1  - Digel, Ilya
T1  - Feasibility of an in-situ microbial decontamination of an ice-melting probe
JF  - Eurasian Chemico-Technological Journal
N2  - Autonomous robotic systems for penetrating thick ice shells with simultaneous collecting of scientific data are very promising devices in both terrestrial (glacier, climate research) and extra-terrestrial applications. Technical challenges in development of such systems are numerous and include 3D-navigation, an appropriate energy source, motion control, etc. Not less important is the problem of forward contamination of the pristine glacial environments with microorganisms and biomolecules from the surface of the probe. This study was devoted to establishing a laboratory model for microbial contamination of a newly constructed ice-melting probe called IceMole and to analyse the viability and amount of the contaminating microorganisms as a function of distance. The used bacterial strains were Bacillus subtilis (ATCC 6051) and Escherichia coli (ATCC 11775). The main objective was development of an efficient and reliable in-situ decontamination method of the melting probe. Therefore, several chemical substances were tested in respect of their efficacy to eliminate bacteria on the surface of the melting probe at low temperature (0 - 5 °C) and at continuous dilution by melted water. Our study has shown that at least 99.9% decontamination of the IceMole can be successfully achieved by the injection of 30% (v/v) hydrogen peroxide and 3% (v/v) sodium hypochlorite into the drilling site. We were able to reproduce this result in both time-dependent and depth-dependent experiments. The sufficient amount of 30% (v/v) H₂O₂ or 3% (v/v) NaClO has been found to be approximately 18 L per cm² of the probe’s surface.
Y1  - 2010
SN  - 1562-3920
U6  - https://doi.org/10.18321/ectj37
VL  - 12
IS  - 2
SP  - 145
EP  - 150
PB  - Institute of Combustion Problems
CY  - Almaty
ER  - 
TY  - JOUR
A1  - Beging, Stefan
A1  - Mlynek, Daniela
A1  - Hataihimakul, Sudkanung
A1  - Poghossian, Arshak
A1  - Baldsiefen, Gerhard
A1  - Busch, Heinz
A1  - Laube, Norbert
A1  - Kleinen, Lisa
A1  - Schöning, Michael Josef
T1  - Field-effect calcium sensor for the determination of the risk of urinary stone  formation
JF  - Sensors and Actuators B: Chemical
N2  - Urinary stone formation has been evolved to a widespread disease during the last years. The reason for the formation of urinary stones are little crystals, mostly composed of calcium oxalate, which are formed in human kidneys. The early diagnosis of the risk for urinary stone formation of patients can be determined by the “Bonn-Risk-Index” method based on the potentiometric detection of the Ca2+-ion concentration and an optical determination of the triggered crystallisation of calcium oxalate in unprocessed urine. In this work, miniaturised capacitive field-effect EMIS (electrolyte-membrane-insulator-semiconductor) sensors have been developed for the determination of the Ca2+-ion concentration in human native urine. The Ca2+-sensitive EMIS sensors have been systematically characterised by impedance spectroscopy, capacitance–voltage and constant–capacitance method in terms of sensitivity, signal stability and response time in both CaCl2 solutions and in native urine. The obtained results demonstrate the suitability of EMIS sensors for the measurement of the Ca2+-ion concentration in native urine of patients.
Y1  - 2010
U6  - https://doi.org/10.1016/j.snb.2008.12.012
SN  - 0925-4005
N1  - 22nd International Conference on Eurosensors: Dresden, Germany, 7-10 September 2008
VL  - 144
IS  - 2
SP  - 374
EP  - 379
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Werner, Frederik
A1  - Miyamoto, Ko-ichiro
A1  - Ackermann, Hans-Josef
A1  - Yoshinobu, Tatsuo
A1  - Schöning, Michael Josef
T1  - FPGA-based LAPS device for the flexible design of sensing sites on functional interfaces
JF  - Physica Status Solidi (A)
N2  - The development of new interfaces for (bio-)chemical sensors requires comprehensive analyses and testing. The light-addressable potentiometric sensor (LAPS) can be used as a platform to investigate the sensitivity of a newly developed interface towards (bio-)chemical agents. LAPS measurements are spatially resolved by utilisation of focused light beams to define individual measurement spots. In this work, a new digitally modulated LAPS set-up based on an FPGA design will be introduced to increase the number of measurement spots, to shorten the measurement time and to improve the measurement accuracy.
Y1  - 2010
U6  - https://doi.org/10.1002/pssa.200983320
SN  - 1862-6300
N1  - Special Issue: Engineering of Functional Interfaces EnFI 2009
VL  - 207
IS  - 4
SP  - 844
EP  - 849
PB  - Wiley-VCH
CY  - Weinheim
ER  -