TY  - CHAP
A1  - Akimbekov, Nuraly S.
A1  - Digel, Ilya
A1  - Sherelkhan, Dinara K.
A1  - Razzaque, Mohammed S.
T1  - Vitamin D and Phosphate Interactions in Health and Disease
T2  - Phosphate Metabolism
N2  - Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis, maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as calcitriol (1,25(OH)2D), not only increases intestinal calcium and phosphate absorption but also facilitates their renal reabsorption, leading to elevated serum calcium and phosphate levels. The interaction of 1,25(OH)2D with its receptor (VDR) increases the efficiency of intestinal absorption of calcium to 30–40% and phosphate to nearly 80%. Serum phosphate levels can also influence 1,25 (OH)2D and fibroblast growth factor 23 (FGF23) levels, i.e., higher phosphate concentrations suppress vitamin D activation and stimulate parathyroid hormone (PTH) release, while a high FGF23 serum level leads to reduced vitamin D synthesis. In the vitamin D-deficient state, the intestinal calcium absorption decreases and the secretion of PTH increases, which in turn causes the stimulation of 1,25(OH)2D production, resulting in excessive urinary phosphate loss. Maintenance of phosphate homeostasis is essential as hyperphosphatemia is a risk factor of cardiovascular calcification, chronic kidney diseases (CKD), and premature aging, while hypophosphatemia is usually associated with rickets and osteomalacia. This chapter elaborates on the possible interactions between vitamin D and phosphate in health and disease.
KW  - Vitamin D
KW  - PTH
KW  - Phosphate
KW  - FGF23
KW  - Klotho
Y1  - 2022
SN  - 978-3-030-91621-3
U6  - http://dx.doi.org/10.1007/978-3-030-91623-7_5
SP  - 37
EP  - 46
PB  - Springer
CY  - Cham
ER  - 
TY  - CHAP
A1  - Pulini, Paola
A1  - Gligorevic, Snjezana
T1  - WIMAX performance in the airport environment
T2  - Multi-carrier systems & solutions 2009. (Lecture notes in electrical engineering ; 41)
N2  - In this paper, the multicarrier physical layers of WiMAX are evaluated in the context of airport data links. The orthogonal frequency-division multiplexing (OFDM) and orthogonal frequency-division multiple-access (OFDMA) cases are applied to the forward link (FL) and reverse link (RL), respectively. The performance of the so called parking and taxi scenarios is presented for airport communications in C-band. Numerical results show that the proposed scheme brings good performance for both the FL and the RL. For the OFDMA case a structure changing called double-tile is also proposed to improve the system performance.
Y1  - 2009
SN  - 978-90-481-2529-6 (Print) ; 978-90-481-2530-2 (Online)
SP  - 301
EP  - 310
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - CHAP
A1  - Schürmann, Volker
A1  - Buda, Aurel
A1  - Jonker, Stefan
A1  - Palmhof, Norman
A1  - Wollert, Jörg
T1  - Wireless in future automotive applications
T2  - Mobile and wireless communications network layer and circuit level design / ed. by Salma Ait Fares ...
Y1  - 2010
SN  - 978-953-307-042-1
SP  - 71
EP  - 92
PB  - Intech
CY  - London
ER  - 
TY  - CHAP
A1  - Buda, Aurel
A1  - Schürmann, Volker
A1  - Wollert, Jörg
T1  - Wireless technologies in factory automation
T2  - Factory automation / ed. by Javier Silvestre-Blanes
Y1  - 2010
SN  - 978-953-7619-42-8
SP  - 29
EP  - 50
PB  - Intech
CY  - London
ER  -