TY - CHAP A1 - Poghossian, Arshak A1 - Bronder, Thomas A1 - Scheja, S. A1 - Wu, Chunsheng A1 - Metzger-Boddien, C. A1 - Keusgen, M. A1 - Schöning, Michael Josef T1 - Label-free Electrostatic Detection of DNA Amplification by PCR Using Capacitive Field-effect Devices T2 - Procedia Engineering N2 - A capacitive field-effect EIS (electrolyte-insulator-semiconductor) sensor modified with a positively charged weak polyelectrolyte of poly(allylamine hydrochloride) (PAH)/single-stranded probe DNA (ssDNA) bilayer has been used for a label-free electrostatic detection of pathogen-specific DNA amplification via polymerase chain reaction (PCR). The sensor is able to distinguish between positive and negative PCR solutions, to detect the existence of target DNA amplicons in PCR samples and thus, can be used as tool for a quick verification of DNA amplification and the successful PCR process. Y1 - 2016 U6 - https://doi.org/10.1016/j.proeng.2016.11.512 SN - 1877-7058 N1 - Proceedings of the 30th anniversary Eurosensors Conference – Eurosensors 2016, 4-7. Sepember 2016, Budapest, Hungary VL - Vol. 168 SP - 514 EP - 517 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Poghossian, Arshak A1 - Bronder, Thomas A1 - Wu, Chunsheng A1 - Schöning, Michael Josef T1 - Label-free sensing of biomolecules by their intrinsic molecular charge using field-effect devices T2 - Semiconductor Micro- and Nanoelectonics : Proceedings of the tenth international conference, Yerevan, Armenia, September 11-13 Y1 - 2015 SN - 978-5-8084-1991-9 SP - 61 EP - 63 ER - TY - JOUR A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - Label-free sensing of biomolecules with field-effect devices for clinical applications JF - Electroanalysis N2 - Among the variety of transducer concepts proposed for label-free detection of biomolecules, the semiconductor field-effect device (FED) is one of the most attractive platforms. As medical techniques continue to progress towards diagnostic and therapies based on biomarkers, the ability of FEDs for a label-free, fast and real-time detection of multiple pathogenic and physiologically relevant molecules with high specificity and sensitivity offers very promising prospects for their application in point-of-care and personalized medicine for an early diagnosis and treatment of diseases. The presented paper reviews recent advances and current trends in research and development of different FEDs for label-free, direct electrical detection of charged biomolecules by their intrinsic molecular charge. The authors are mainly focusing on the detection of the DNA hybridization event, antibody-antigen affinity reaction as well as clinically relevant biomolecules such as cardiac and cancer biomarkers. Y1 - 2014 U6 - https://doi.org/10.1002/elan.201400073 SN - 1521-4109 (E-Journal); 1040-0397 (Print) VL - 26 IS - 6 SP - 1197 EP - 1213 PB - Wiley-VCH CY - Weinheim ER - TY - CHAP A1 - Bung, Daniel Bernhard ED - Rowinski, Pawel T1 - Laboratory models of free-surface flows T2 - Rivers - physical, fluvial and environmental processes N2 - Hydraulic modeling is the classical approach to investigate and describe complex fluid motion. Many empirical formulas in the literature used for the hydraulic design of river training measures and structures have been developed using experimental data from the laboratory. Although computer capacities have increased to a high level which allows to run complex numerical simulations on standard workstation nowadays, non-standard design of structures may still raise the need to perform physical model investigations. These investigations deliver insight into details of flow patterns and the effect of varying boundary conditions. Data from hydraulic model tests may be used for calibration of numerical models as well. As the field of hydraulic modeling is very complex, this chapter intends to give a short overview on capacities and limits of hydraulic modeling in regard to river flows and hydraulic structures only. The reader shall get a first idea of modeling principles and basic considerations. More detailed information can be found in the references. KW - Physical modeling KW - Similitude KW - Open channels KW - Hydraulic structures Y1 - 2015 SN - 978-3-319-17718-2 ; 978-3-319-17719-9 U6 - https://doi.org/10.1007/978-3-319-17719-9_9 SP - 213 EP - 228 PB - Springer CY - Cham ER - TY - JOUR A1 - Zischank, Wolfgang J. A1 - Heidler, Fridolin A1 - Wiesinger, J. A1 - Metwally, I. A1 - Kern, Alexander A1 - Seevers, M. T1 - Laboratory simulation of direct lightning strokes to a modeled building : measurement of magnetic fields and included voltages JF - Journal of electrostatics. 60 (2004), H. 2 - 4 Y1 - 2004 SN - 0304-3886 N1 - ISSN der E-Ausg.: 0304-3886 SP - 223 EP - 232 ER - TY - CHAP A1 - Zischank, Wolfgang J. A1 - Heidler, Fridolin A1 - Kern, Alexander A1 - Metwally, I. A. A1 - Wiesinger, J. A1 - Seevers, M. T1 - Laboratory simulation of direct lightning strokes to a modelled building - measurement of magnetic fields and induced voltages N2 - In IEC 61312-2 equations for the assessment of the magnetic fields inside structures due to a direct lightning strike are given. These equations are based on computer simulations for shields consisting of a single-layer steel grid of a given mesh width. Real constructions, however, contain at least two layers of reinforcement steel grids. The objective of this study was to experimentally determine the additional shielding effectiveness of a second reinforcement layer compared to a single-layer grid. To this end, simulated structures were set up in the high current laboratory. The structures consisted of cubic cages of 2 m side length with one or with two reinforcement grids, respectively. The structures were exposed to direct lightning currents representing the variety of anticipated lightning current waveforms. The magnetic fields and their derivatives at several positions inside the structure as well as the voltage between “floor” and “roof” in the center were determined for different current injection points. From these data the improvement of the shielding caused by a second reinforcement layer is derived. KW - Direkter Blitzschlag KW - Elektromagnetischer Schutzschild KW - Magnetische Felder KW - Induzierte Spannungen KW - Stahlbetonkonstruktion KW - Lightning KW - electromagnetic shielding KW - magnetic field KW - reinforced concrete KW - induced voltage Y1 - 2002 ER - TY - JOUR A1 - Schwarzer, Klemens A1 - Werner, M. A1 - Hartz, T. T1 - Lacasa - an instrument for the energy analysis and optimisation of buildings including technical equipment JF - Proceedings / organised by: ISES Europe ... [Ed.: Deutsche Gesellschaft für Sonnenenergie e.V. - DGS, Munich ; PSE GmbH - Forschung Entwicklung Marketing, Freiburg]. - Vol. 2 Y1 - 2004 SN - 3-9809656-2-7 N1 - EuroSun <5, 2004, Freiburg, Breisgau> ; Internationales Sonnenforum <14, 2004, Freiburg, Breisgau> ; Deutsche Gesellschaft für Sonnenenergie ; CD-ROM-Ausg.: ISBN 3-9809656-4-3 SP - 2-489-2-494 PB - PSE CY - Freiburg [Breisgau] ER - TY - BOOK A1 - Schwarzer, Klemens T1 - Lacasa : Einsatz von MATLAB-Simulink zur energetischen Analyse und Optimierung von Alt- und Neubauten inklusive Heizungs-, Lüftungs- und Klimatechnik / Hrsg.: FIA-Projekt, Forschungs-Informations-Austausch im Fachinstitut Gebäude-Klima e.V. Projekt: Solar-Institut Jülich an der Fachhochschule Aachen Y1 - 2004 SN - 3-938210-07-9 PB - FIA-Projekt im Fachinst. Gebäude-Klima CY - Bietigheim-Bissingen ER - TY - JOUR A1 - Mertens, Josef T1 - Laminar flow for supersonic transports JF - Proceedings : March 16 - 18, 1992, Congress Centrum, Hamburg, Federal Republic of Germany / organized jointly by: Deutsche Gesellschaft für Luft- und Raumfahrt e.V. ... [Programme committee J. Szodruch ...] Y1 - 1992 SN - 3-922010-73-3 N1 - DGLR-Bericht ; 92,06 SP - 319 EP - 323 PB - DGLR CY - Bonn ER - TY - CHAP A1 - Mertens, Josef T1 - Laminar leading edges: manufacturing, contamination, and operational aspects - results from the German RaWid programme N2 - RaWid was the German national technology programme on transonic aerodynamics and supporting technologies, lasting from 1995 to 1998. One of the main topics was laminar wing development. Besides aerodynamic design work, many operational aspects were investigated. A manufacturing concept was developed to be applied to operational laminar wings and empennages. It was built in a large scale manufacturing demonstrator with the aerodynamic shape of a 1,5 m section of the A320 fin nose. Tolerances in shape and roughness fulfilled all requirements. The construction can easily be adapted to varying stiffness and strength requirements. Weight and manufacturing costs are comparable to common nose designs. The mock-up to be designed in ALTTA is based on this manufacturing principle. Another critical point is contamination of suction surfaces. Several tests were performed to investigate perforated titanium suction surfaces at realistic operational conditions: - a one year flight test with a suction plate in the stagnation area of the Airbus "Beluga" - a one year test of several suction plates in a ground test near the airport - a one year test of a working suction ground test installation at all weather conditions. No critical results were found. There is no long term suction degradation visible. Icing conditions and ground de-icing fluids used on airports did not pose severe problems. Some problems detected require only respection of weak design constraints. KW - Laminare Strömung KW - Ansaugsystem KW - Profilumströmung KW - Laminarprofil KW - RaWid KW - hybrid laminar flow KW - suction systems KW - suction structure KW - contamination KW - operational aspects Y1 - 2000 ER - TY - JOUR A1 - Wittmann, Klaus A1 - Ulamec, S A1 - Richter, L T1 - Lander Systems for Planetary Missions JF - Laboratory astrophysics and space research / ed. by P. Ehrenfreund Y1 - 1999 SN - 0-7923-5338-2 N1 - Serie Astrophysics and space science library 236 SP - 597 EP - 621 PB - Kluwer CY - Dordrecht [u.a.] ER - TY - JOUR A1 - Ferrein, Alexander A1 - Beck, Daniel A1 - Lakemeyer, Gerhard T1 - Landmark-Based Representations for Navigating Holonomic Soccer Robots / Beck, Daniel ; Ferrein, Alexander ; Lakemeyer, Gerhard JF - RoboCup 2008 : robot soccer world cup XII / Luca Iocchi ... (eds.) Y1 - 2009 SN - 978-3-642-02921-9 N1 - Lecture Notes in Computer Science ; 5399 SP - 25 EP - 36 PB - Springer CY - Heidelberg ER - TY - JOUR A1 - Dantism, Shahriar A1 - Röhlen, Desiree A1 - Dahmen, Markus A1 - Wagner, Torsten A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - LAPS-based monitoring of metabolic responses of bacterial cultures in a paper fermentation broth JF - Sensors and Actuators B: Chemical N2 - As an alternative renewable energy source, methane production in biogas plants is gaining more and more attention. Biomass in a bioreactor contains different types of microorganisms, which should be considered in terms of process-stability control. Metabolically inactive microorganisms within the fermentation process can lead to undesirable, time-consuming and cost-intensive interventions. Hence, monitoring of the cellular metabolism of bacterial populations in a fermentation broth is crucial to improve the biogas production, operation efficiency, and sustainability. In this work, the extracellular acidification of bacteria in a paper-fermentation broth is monitored after glucose uptake, utilizing a differential light-addressable potentiometric sensor (LAPS) system. The LAPS system is loaded with three different model microorganisms (Escherichia coli, Corynebacterium glutamicum, and Lactobacillus brevis) and the effect of the fermentation broth at different process stages on the metabolism of these bacteria is studied. In this way, different signal patterns related to the metabolic response of microorganisms can be identified. By means of calibration curves after glucose uptake, the overall extracellular acidification of bacterial populations within the fermentation process can be evaluated. Y1 - 2020 U6 - https://doi.org/10.1016/j.snb.2020.128232 SN - 0925-4005 VL - 320 IS - Art. 128232 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Seefeldt, Patric A1 - Bauer, Waldemar A1 - Dachwald, Bernd A1 - Grundmann, Jan Thimo A1 - Straubel, Marco A1 - Sznajder, Maciej A1 - Tóth, Norbert A1 - Zander, Martin E. T1 - Large lightweight deployable structures for planetary defence: solar sail propulsion, solar concentrator payloads, large-scale photovoltaic power T2 - 4th IAA Planetary Defense Conference - PDC 2015, 13-17 April 2015, Frascati, Roma, Italy Y1 - 2015 N1 - IAA-PDC-15-P-20 ER - TY - JOUR A1 - Roesner, Andreas A1 - Scheik, Sven A1 - Olowinsky, Alexander A1 - Gillner, Arnold A1 - Reisgen, Uwe A1 - Schleser, Markus T1 - Laser assisted joining of plastic metal hybrids JF - Lasers in manufacturing 2011 : proceedings of the sixth International WLT Conference on Lasers in Manufacturing, Munich, May 23 - 26 2011. (Physics procedia ; Vol. 12 (2011), Part B) Y1 - 2011 SN - 1875-3892 (E-Journal); 1875-3884 (Print) SP - 370 EP - 377 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Reisgen, Uwe A1 - Olschok, Simon A1 - Jakobs, Stefan A1 - Schleser, Markus A1 - Mokrov, Oleg A1 - Rossiter, Eduardo T1 - Laser beam submerged arc hybrid welding JF - Physics procedia N2 - The laser beam-submerged arc hybrid welding method originates from the knowledge that, with increasing penetration depth, the laser beam process has a tendency to pore formation in the lower weld regions. The coupling with the energy-efficient submerged-arc process improves degassing and reduces the tendency to pore formation. The high deposition rate of the SA process in combination with the laser beam process offers, providing the appropriate choice of weld preparation, the possibility of welding plates with a thickness larger than 20° mm in a single pass, and also of welding thicker plates with the double-sided single pass technique. Y1 - 2012 U6 - https://doi.org/10.1016/j.phpro.2012.10.016 SN - 1875-3892 N1 - Part of special issue "Laser assisted net shape engineering 7 (LANE 2012)" VL - 39 SP - 75 EP - 83 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Ferrein, Alexander A1 - Strack, Andreas A1 - Lakemeyer, Gerhard T1 - Laser-Based Localization with Sparse Landmarks / Strack, Andreas ; Ferrein, Alexander ; Lakemeyer, Gerhard JF - RoboCup 2005: Robot Soccer World Cup IX Y1 - 2006 SN - 978-3-540-35437-6 N1 - Lecture Notes in Computer Science ; 4020 SP - 569 EP - 576 PB - Springer CY - Berlin ER - TY - JOUR A1 - Ermolenko, Y. E. A1 - Yoshinobu, T. A1 - Mourzina, Y. G. A1 - Vlasov, Y. G. A1 - Schöning, Michael Josef A1 - Iwasaki, H. T1 - Laserscanned transducer (LSST) as a multisensor system JF - Sensors and Actuators B. 103 (2004), H. 1-2 Y1 - 2004 SN - 0925-4005 SP - 457 EP - 462 ER - TY - JOUR A1 - Gebhardt, Andreas T1 - Laserwelding with fillerwire JF - LIA handbook of laser material processing / Laser Institute of America Y1 - 2001 SN - 3-540-41770-2 N1 - Chapter 11.2.12 CY - Orlando, Florida ER - TY - JOUR A1 - Mottaghy, Darius A1 - Rath, Volker T1 - Latent heat effects in subsurface heat transport modelling and their impact on palaeotemperature reconstructions JF - Geophysical Journal International Y1 - 2006 U6 - https://doi.org/10.1111/j.1365-246X.2005.02843.x SN - 1365-246X VL - 164 IS - 1 SP - 236 EP - 245 ER -