TY  - JOUR
A1  - Digel, Ilya
A1  - Wehlitz, V.
A1  - Kayser, Peter
A1  - Figiel-Lange, A.
A1  - Bassam, Rasha
A1  - Rundstedt, F. von
T1  - Suspension depletion approach for exemption of infected Solanum jasminoides cells from pospiviroids
JF  - Plant Pathology
N2  - Despite numerous studies, viroid elimination from infected plants remains a very challenging task. This study introduces for the first time a novel ‘suspension depletion’ approach for exemption of Solanum jasminoides plants from viroids. The proposed method implies initial establishment of suspension cultures of the infected plant cells. The suspended cells were then physically treated (mild thermotherapy, 33 °C), which presumably delayed the replication of the viroid. The viroid concentration in the treated biomass was monitored weekly using pospiviroid-specific PCR. After 10–12 weeks of continuous treatment, a sufficient decrease in viroid concentration was observed such that the infection became undetectable by PCR. The treated single cells then gave rise to microcolonies on a solid culture medium and the obtained viroid-negative clones were further promoted to regenerate into viroid-free plants. Three years of accumulated experimental data suggests feasibility, broad applicability, and good efficacy of the proposed approach.
Y1  - 2018
U6  - https://doi.org/10.1111/ppa.12750
SN  - 1365-3059
VL  - 67
IS  - 2
SP  - 358
EP  - 365
PB  - Wiley
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Biewendt, Marcel
T1  - Sustainable development: A quantitative analysis regarding the impact of resource rents on state welfare from 2002 to 2017
JF  - SocioEconomic Challenges
N2  - This paper uses a quantitative analysis to examine the interdependence and impact of resource rents on socio-economic development from 2002 to 2017. Nigeria and Norway have been chosen as reference countries due to their abundance of natural resources by similar economic performance, while the ranking in the Human Development Index differs dramatically. As the Human Development Index provides insight into a country’s cultural and socio-economic characteristics and development in addition to economic indicators, it allows a comparison of the two countries. The hypothesis presented and discussed in this paper was researched before. A qualitative research approach was used in the author’s master’s thesis “The Human Development Index (HDI) as a Reflection of Resource Abundance (using Nigeria and Norway as a case study)” in 2018. The management of scarce resources is an important aspect in the development of modern countries and those on the threshold of becoming industrialised nations. The effects of a mistaken resource management are not only of a purely economic nature but also of a social and socio-economic nature. In order to present a partial aspect of these dependencies and influences this paper uses a quantitative analysis to examine the interdependence and impact of resource rents on socio-economic development from 2002 to 2017. Nigeria and Norway have been chosen as reference countries due to their abundance of natural resources by similar economic performance, while the ranking in the Human Development Index differs significantly. As the Human Development Index provides insight into a country’s cultural and socio-economic characteristics and development in addition to economic indicators, it allows a comparison of the two countries. This paper found out in a holistic perspective that (not or poorly managed) resource wealth in itself has a negative impact on socio-economic development and significantly reduces the productivity of the citizens of a state. This is expressed in particular for the years 2002 till 2017 in a negative correlation of GDP per capita and HDI value with the share respectively the size of resources in the GDP of a country.
KW  - socio-economic welfare
KW  - resource abundance
KW  - sustainability
KW  - Human Development Index
Y1  - 2020
U6  - https://doi.org/10.21272/sec.4(4).119-131.2020
SN  - 2520-6214
VL  - 4
IS  - 4
SP  - 119
EP  - 131
PB  - ARMG Publishing
CY  - Sumy
ER  - 
TY  - JOUR
A1  - Hafidi, Youssef
A1  - El Hatka, Hicham
A1  - Schmitz, Dominik
A1  - Krauss, Manuel
A1  - Pettrak, Jürgen
A1  - Biel, Markus
A1  - Ittobane, Najim
T1  - Sustainable soil additives for water and micronutrient supply: swelling and chelating properties of polyaspartic acid hydrogels utilizing newly developed crosslinkers
JF  - Gels
N2  - Drought and water shortage are serious problems in many arid and semi-arid regions. This problem is getting worse and even continues in temperate climatic regions due to climate change. To address this problem, the use of biodegradable hydrogels is increasingly important for the application as water-retaining additives in soil. Furthermore, efficient (micro-)nutrient supply can be provided by the use of tailored hydrogels. Biodegradable polyaspartic acid (PASP) hydrogels with different available (1,6-hexamethylene diamine (HMD) and L-lysine (LYS)) and newly developed crosslinkers based on diesters of glycine (GLY) and (di-)ethylene glycol (DEG and EG, respectively) were synthesized and characterized using Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM) and regarding their swelling properties (kinetic, absorbency under load (AUL)) as well as biodegradability of PASP hydrogel. Copper (II) and zinc (II), respectively, were loaded as micronutrients in two different approaches: in situ with crosslinking and subsequent loading of prepared hydrogels. The results showed successful syntheses of di-glycine-ester-based crosslinkers. Hydrogels with good water-absorbing properties were formed. Moreover, the developed crosslinking agents in combination with the specific reaction conditions resulted in higher water absorbency with increased crosslinker content used in synthesis (10% vs. 20%). The prepared hydrogels are candidates for water-storing soil additives due to the biodegradability of PASP, which is shown in an exemple. The incorporation of Cu(II) and Zn(II) ions can provide these micronutrients for plant growth.
KW  - micronutrients
KW  - swelling properties
KW  - biodegradable polymers
KW  - hydrogels
KW  - superabsorbent polymers
KW  - glycine
KW  - polyaspartic acid
Y1  - 2024
U6  - https://doi.org/10.3390/gels10030170
SN  - 2310-2861
VL  - 10
IS  - 3
SP  - Artikel 170
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Leise, Philipp
A1  - Eßer, Arved
A1  - Eichenlaub, Tobias
A1  - Schleiffer, Jean-Eric
A1  - Altherr, Lena
A1  - Rinderknecht, Stephan
A1  - Pelz, Peter F.
T1  - Sustainable system design of electric powertrains - comparison of optimization methods
JF  - Engineering Optimization
N2  - The transition within transportation towards battery electric vehicles can lead to a more sustainable future. To account for the development goal ‘climate action’ stated by the United Nations, it is mandatory, within the conceptual design phase, to derive energy-efficient system designs. One barrier is the uncertainty of the driving behaviour within the usage phase. This uncertainty is often addressed by using a stochastic synthesis process to derive representative driving cycles and by using cycle-based optimization. To deal with this uncertainty, a new approach based on a stochastic optimization program is presented. This leads to an optimization model that is solved with an exact solver. It is compared to a system design approach based on driving cycles and a genetic algorithm solver. Both approaches are applied to find efficient electric powertrains with fixed-speed and multi-speed transmissions. Hence, the similarities, differences and respective advantages of each optimization procedure are discussed.
KW  - Powertrain
KW  - stochastic optimization
KW  - global optimization
KW  - genetic algorithm
Y1  - 2021
U6  - https://doi.org/10.1080/0305215X.2021.1928660
SN  - 0305-215X
PB  - Taylor & Francis
CY  - London
ER  - 
TY  - JOUR
A1  - Bernecker, Andreas
A1  - Klier, Julia
A1  - Stern, Sebastian
A1  - Thiel, Lea
T1  - Sustaining high performance beyond public-sector pilot projects.
Y1  - 2018
IS  - September 2018
ER  - 
TY  - JOUR
A1  - Hackl, M.
A1  - Andermahr, J.
A1  - Staat, Manfred
A1  - Bremer, I.
A1  - Borggrefe, J.
A1  - Prescher, A.
A1  - Müller, L. P.
A1  - Wegmann, K.
T1  - Suture button reconstruction of the central band of the interosseous membrane in Essex-Lopresti lesions: a comparative biomechanical investigation
JF  - The Journal of Hand Surgery (European Volume)
Y1  - 2017
U6  - https://doi.org/10.1177/1753193416665943
SN  - 2043-6289 (Online)
SN  - 1753-1934 (Print)
VL  - 42
IS  - 4
SP  - 370
EP  - 376
PB  - Sage
CY  - London
ER  - 
TY  - JOUR
A1  - Kodomskoi, Leonid
A1  - Kotliar, Konstantin
A1  - Schröder, Andreas
A1  - Weiss, Michael
A1  - Hille, Konrad
T1  - Suture-Probe Canaloplasty as an Alternative to Canaloplasty using the iTrack™ Microcatheter
JF  - Journal of Glaucoma
Y1  - 2019
U6  - https://doi.org/10.1097/IJG.0000000000001321
SN  - 1057-0829
IS  - Epub ahead of print
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - JOUR
A1  - Lehnertz, Klaus
A1  - Bialonski, Stephan
A1  - Horstmann, Marie-Therese
A1  - Krug, Dieter
A1  - Rothkegel, Alexander
A1  - Staniek, Matthäus
A1  - Wagner, Tobias
T1  - Synchronization phenomena in human epileptic brain networks
JF  - Journal of neuroscience methods
Y1  - 2009
U6  - https://doi.org/10.1016/j.jneumeth.2009.05.015
SN  - 0165-0270
VL  - 183
IS  - 1
SP  - 42
EP  - 48
ER  - 
TY  - JOUR
A1  - Esch, Thomas
A1  - Salber, Wolfgang
A1  - Wolters, Peter
A1  - Geiger, José
A1  - Dilthey, Jochen
T1  - Synergies of variable valve actuation and direct injection
JF  - Direct injection SI engine technology 2002 : [SAE 2002 world congress, Detroit, Michigan, USA, March 4 - 7, 2002].
Y1  - 2002
SN  - 0-7680-0961-8
N1  - Konferenz-Einzelbericht
SP  - 45
EP  - 53
PB  - Society of Automotive Engineers
CY  - Warrendale, Pa
ER  - 
TY  - JOUR
A1  - Turck, Christoph W.
A1  - Berndt, Heinz
T1  - Synthese definierter Peptid-Derivate durch Aminolyse von 3-(Nα-Acyl-peptidyloxy)-2-hydroxy-N-alkylbenzamiden bei erhöhten Temperaturen, I : Synthese des Modellpeptid-Derivates Z-Ala-Phe-Gly-N(Et)2
JF  - Hoppe-Seyler´s Zeitschrift für physiologische Chemie
Y1  - 1981
U6  - https://doi.org/10.1515/bchm2.1981.362.1.821
SN  - 1437-4315
SN  - 0018-4888
VL  - 362
IS  - 1
SP  - 821
EP  - 828
ER  - 
TY  - JOUR
A1  - Wolf, Günter
A1  - Berndt, Heinz
A1  - Brandenburg, Dietrich
T1  - Synthese der [LysA13] Rinderinsulin-A-Kette in der Form [Lys(Tfa)A13]A(SO3H)4 und NαA1-Msc-[LysA13]A(SO3H)4 unter Verwendung des S-tert-Butylmercapto-Restes als Thiolschutzgruppe
JF  - Hoppe-Seyler's Zeitschrift für physiologische Chemie
Y1  - 1979
U6  - https://doi.org/10.1515/bchm2.1979.360.2.1569
SN  - 1437-4315
SN  - 0018-4888
VL  - 360
IS  - 2
SP  - 1569
EP  - 1578
ER  - 
TY  - JOUR
A1  - Gielen, Hans-Günther
A1  - Wolf, Günter
A1  - Berndt, Heinz
A1  - Zahn, Helmut
T1  - Synthese der Fragmente A1–8, A9–15 und A16–21 der Schafinsulin-A-Kette unter Verwendung des S-tert-Butylmercaptorestes als Thiolschutzgruppe
JF  - Hoppe-Seyler's Zeitschrift für physiologische Chemie
Y1  - 1979
U6  - https://doi.org/10.1515/bchm2.1979.360.2.1535
SN  - 1437-4315
SN  - 0018-4888
VL  - 360
IS  - 2
SP  - 1535
EP  - 1548
ER  - 
TY  - JOUR
A1  - Berndt, Heinz
T1  - Synthese der Sequenz 71—86 des Humanproinsulins, I : Synthese der Sequenz 71—86 als monomeres cyclisches Biscystinpeptidderivat und als Tetra-S-tritylderivat
JF  - Hoppe-Seyler's Zeitschrift für physiologische Chemie
Y1  - 1979
U6  - https://doi.org/10.1515/bchm2.1979.360.1.747
SN  - 1437-4315
SN  - 0018-4888
VL  - 360
IS  - 1
SP  - 747
EP  - 760
ER  - 
TY  - JOUR
A1  - Berndt, Heinz
T1  - Synthese der Sequenz 71—86 des Humanproinsulins, III : Synthese über die Fragmente 71—78 und 79—86
JF  - Hoppe-Seyler's Zeitschrift für physiologische Chemie
Y1  - 1979
U6  - https://doi.org/10.1515/bchm2.1979.360.1.765
SN  - 1437-4315
SN  - 0018-4888
VL  - 360
IS  - 1
SP  - 765
EP  - 772
ER  - 
TY  - JOUR
A1  - Wolf, Wilhelm
A1  - Berndt, Heinz
A1  - Brandenburg, Dietrich
T1  - Synthese von Fragmenten einer [LysA13] Rinder-Insulin-A-Kette unter Verwendung des S-tert-Butylmercaptorestes als Thiolschutz
JF  - Hoppe-Seyler's Zeitschrift für physiologische Chemie
Y1  - 1979
U6  - https://doi.org/10.1515/bchm2.1979.360.2.1549
SN  - 1437-4315
SN  - 0018-4888
VL  - 360
IS  - 2
SP  - 1549
EP  - 1558
ER  - 
TY  - JOUR
A1  - Meyer-Stork, L. Sebastian
A1  - Höcker, Hartwig
A1  - Berndt, Heinz
T1  - Syntheses and reactions of urethanes of cellobiose and cellulose-containing uretdione groups
JF  - Journal of applied polymer science
Y1  - 1992
SN  - 1097-4628
VL  - 44
IS  - 6
SP  - 1043
EP  - 1049
ER  - 
TY  - JOUR
A1  - Pellegrini, Paul A.
A1  - Howell, Nicholas R.
A1  - Shepherd, Rachael K.
A1  - Lengkeek, Nigel A.
A1  - Paulßen, Elisabeth
A1  - Katsifis, Andrew G.
A1  - Greguric, Ivan
T1  - Synthesis and Radiolabelling of DOTA-Linked Glutamine Analogues with 67,68Ga as Markers for Increased Glutamine Metabolism in Tumour Cells
JF  - Molecules
Y1  - 2013
U6  - https://doi.org/10.3390/molecules18067160
SN  - 1420-3049
VL  - 18
IS  - 6
SP  - 7160
EP  - 7178
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Immel, Timo
A1  - Grützke, Martin
A1  - Späte, Anne-Katrin
A1  - Groth, Ulrich
A1  - Öhlschläger, Peter
A1  - Huhn, Thomas
T1  - Synthesis and X-ray structure analysis of a heptacoordinate titanium(IV)-bis-chelate with enhanced in vivo antitumor efficacy
JF  - Chemical Communications
N2  - Chelate stabilization of a titanium(IV)–salan alkoxide by ligand exchange with 2,6-pyridinedicarboxylic acid (dipic) resulted in heptacoordinate complex 3 which is not redox-active, stable on silica gel and has increased aqueous stability. 3 is highly toxic in HeLa S3 and Hep G2 and has enhanced antitumor efficacy in a mouse cervical-cancer model.
Y1  - 2012
U6  - https://doi.org/10.1039/C2CC31624B
SN  - 1364-548X
VL  - 48
IS  - 46
SP  - 5790
EP  - 5792
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Droop, Philipp
A1  - Chen, Shaohuang
A1  - Radford, Melissa J.
A1  - Paulßen, Elisabeth
A1  - Gates, Byron D.
A1  - Reilly, Raymond M.
A1  - Radchenko, Valery
A1  - Hoehr, Cornelia
T1  - Synthesis of 197m/gHg labelled gold nanoparticles for targeted radionuclide therapy
JF  - Radiochimica Acta
N2  - Meitner-Auger-electron emitters have a promising potential for targeted radionuclide therapy of cancer because of their short range and the high linear energy transfer of Meitner-Auger-electrons (MAE). One promising MAE candidate is 197m/gHg with its half-life of 23.8 h and 64.1 h, respectively, and high MAE yield. Gold nanoparticles (AuNPs) that are labelled with 197m/gHg could be a helpful tool for radiation treatment of glioblastoma multiforme when infused into the surgical cavity after resection to prevent recurrence. To produce such AuNPs, 197m/gHg was embedded into pristine AuNPs. Two different syntheses were tested starting from irradiated gold containing trace amounts of 197m/gHg. When sodium citrate was used as reducing agent, no 197m/gHg labelled AuNPs were formed, but with tannic acid, 197m/gHg labeled AuNPs were produced. The method was optimized by neutralizing the pH (pH = 7) of the Au/197m/gHg solution, which led to labelled AuNPs with a size of 12.3 ± 2.0 nm as measured by transmission electron microscopy. The labelled AuNPs had a concentration of 50 μg (gold)/mL with an activity of 151 ± 93 kBq/mL (197gHg, time corrected to the end of bombardment).
KW  - 197m/gHg
KW  - Gold nanoparticle (AuNP)
KW  - Meitner-Auger-electron (MAE)
KW  - Targeted radionuclide therapy (TRT)
Y1  - 2023
U6  - https://doi.org/10.1515/ract-2023-0144
SN  - 2193-3405
VL  - 111
IS  - 10
SP  - 773
EP  - 779
PB  - De Gruyter
CY  - Berlin [u.a.]
ER  - 
TY  - JOUR
A1  - Nokihara, Kiyoshi
A1  - Berndt, Heinz
T1  - Synthesis of hapten–polypeptide conjugates as antigen models for the N-terminal region of the α-2-chain of rabbit skin collagen
JF  - Journal of the Royal Society of Chemistry: Perkin Transactions 1
N2  - Synthesis of derivatives of the peptide sequence L-pyroglutamyl-L-phenylalanyl-L-aspartyl-glycyl-L-lysyl-glycyl-glycyl-glycine as the antigenic determinant representing the N-terminal non-helical region of the α-2-chain of rabbit skin collagen, and conjugation to two different polypeptide carriers, are described.
Y1  - 1978
U6  - https://doi.org/10.1039/P19780000260
SN  - 1364-5463
SN  - 0300-922X
SN  - 1470-4358
VL  - 1978
IS  - 3
SP  - 260
EP  - 263
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  -