TY - CHAP A1 - Steuer-Dankert, Linda A1 - Leicht-Scholten, Carmen T1 - Perceiving diversity : an explorative approach in a complex research organization. T2 - Diversity and discrimination in research organizations N2 - Diversity management is seen as a decisive factor for ensuring the development of socially responsible innovations (Beacham and Shambaugh, 2011; Sonntag, 2014; López, 2015; Uebernickel et al., 2015). However, many diversity management approaches fail due to a one-sided consideration of diversity (Thomas and Ely, 2019) and a lacking linkage between the prevailing organizational culture and the perception of diversity in the respective organization. Reflecting the importance of diverse perspectives, research institutions have a special responsibility to actively deal with diversity, as they are publicly funded institutions that drive socially relevant development and educate future generations of developers, leaders and decision-makers. Nevertheless, only a few studies have so far dealt with the influence of the special framework conditions of the science system on diversity management. Focusing on the interdependency of the organizational culture and diversity management especially in a university research environment, this chapter aims in a first step to provide a theoretical perspective on the framework conditions of a complex research organization in Germany in order to understand the system-specific factors influencing diversity management. In a second step, an exploratory cluster analysis is presented, investigating the perception of diversity and possible influencing factors moderating this perception in a scientific organization. Combining both steps, the results show specific mechanisms and structures of the university research environment that have an impact on diversity management and rigidify structural barriers preventing an increase of diversity. The quantitative study also points out that the management level takes on a special role model function in the scientific system and thus has an influence on the perception of diversity. Consequently, when developing diversity management approaches in research organizations, it is necessary to consider the top-down direction of action, the special nature of organizational structures in the university research environment as well as the special role of the professorial level as role model for the scientific staff. KW - Diversity management KW - Organizational culture KW - Change management KW - Psychological concepts KW - Perception Y1 - 2022 SN - 978-1-80117-959-1 (Print) SN - 978-1-80117-956-0 (Online) U6 - http://dx.doi.org/10.1108/978-1-80117-956-020221010 SP - 365 EP - 392 PB - Emerald Publishing Limited CY - Bingley ER - TY - JOUR A1 - Fiedler, Thomas M. A1 - Orzada, Stephan A1 - Flöser, Martina A1 - Rietsch, Stefan H. G. A1 - Schmidt, Simon A1 - Stelter, Jonathan K. A1 - Wittrich, Marco A1 - Quick, Harald H. A1 - Bitz, Andreas A1 - Ladd, Mark E. T1 - Performance and safety assessment of an integrated transmitarray for body imaging at 7 T under consideration of specificabsorption rate, tissue temperature, and thermal dose JF - NMR in Biomedicine N2 - In this study, the performance of an integrated body-imaging array for 7 T with 32 radiofrequency (RF) channels under consideration of local specific absorption rate (SAR), tissue temperature, and thermal dose limits was evaluated and the imaging performance was compared with a clinical 3 T body coil. Thirty-two transmit elements were placed in three rings between the bore liner and RF shield of the gradient coil. Slice-selective RF pulse optimizations for B1 shimming and spokes were performed for differently oriented slices in the body under consideration of realistic constraints for power and local SAR. To improve the B1+ homogeneity, safety assessments based on temperature and thermal dose were performed to possibly allow for higher input power for the pulse optimization than permissible with SAR limits. The results showed that using two spokes, the 7 T array outperformed the 3 T birdcage in all the considered regions of interest. However, a significantly higher SAR or lower duty cycle at 7 T is necessary in some cases to achieve similar B1+ homogeneity as at 3 T. The homogeneity in up to 50 cm-long coronal slices can particularly benefit from the high RF shim performance provided by the 32 RF channels. The thermal dose approach increases the allowable input power and the corresponding local SAR, in one example up to 100 W/kg, without limiting the exposure time necessary for an MR examination. In conclusion, the integrated antenna array at 7 T enables a clinical workflow for body imaging and comparable imaging performance to a conventional 3 T clinical body coil. KW - body imaging at 7 T MRI KW - thermal dose KW - tissue temperature KW - transmit antenna arrays Y1 - 2022 U6 - http://dx.doi.org/10.1002/nbm.4656 SN - 0952-3480 (Print) SN - 1099-1492 (Online) VL - 35 IS - 5 SP - 1 EP - 17 PB - Wiley ER - TY - GEN A1 - Feldmann, Marco A1 - Francke, Gero A1 - Espe, Clemes A1 - Chen, Qian A1 - Baader, Fabian A1 - Boxberg, Marc S. A1 - Sustrate, Anna-Marie A1 - Kowalski, Julia A1 - Dachwald, Bernd T1 - Performance data of an ice-melting probe from field tests in two different ice environments N2 - This dataset was acquired at field tests of the steerable ice-melting probe "EnEx-IceMole" (Dachwald et al., 2014). A field test in summer 2014 was used to test the melting probe's system, before the probe was shipped to Antarctica, where, in international cooperation with the MIDGE project, the objective of a sampling mission in the southern hemisphere summer 2014/2015 was to return a clean englacial sample from the subglacial brine reservoir supplying the Blood Falls at Taylor Glacier (Badgeley et al., 2017, German et al., 2021). The standardized log-files generated by the IceMole during melting operation include more than 100 operational parameters, housekeeping information, and error states, which are reported to the base station in intervals of 4 s. Occasional packet loss in data transmission resulted in a sparse number of increased sampling intervals, which where compensated for by linear interpolation during post processing. The presented dataset is based on a subset of this data: The penetration distance is calculated based on the ice screw drive encoder signal, providing the rate of rotation, and the screw's thread pitch. The melting speed is calculated from the same data, assuming the rate of rotation to be constant over one sampling interval. The contact force is calculated from the longitudinal screw force, which es measured by strain gauges. The used heating power is calculated from binary states of all heating elements, which can only be either switched on or off. Temperatures are measured at each heating element and averaged for three zones (melting head, side-wall heaters and back-plate heaters). KW - Ocean Worlds KW - Icy Moons KW - Cryobot KW - Analogue Environments KW - Melting Efficiency KW - Melting Performance KW - Melting Probe KW - Ice Melting Y1 - 2022 U6 - http://dx.doi.org/10.5281/zenodo.6094866 N1 - Forschungsdaten zu "Field-test performance of an ice-melting probe in a terrestrial analogue environment" (https://opus.bibliothek.fh-aachen.de/opus4/frontdoor/index/index/docId/10889) ER - TY - BOOK A1 - Laumann, Jörg A1 - Feldmann, Markus A1 - Frickel, Jörg A1 - Krahwinkel, Manuel A1 - Kraus, Matthias A1 - Stranghöner, Natalie A1 - Ummenhofer, Thomas T1 - Petersen Stahlbau : Grundlagen der Berechnung und baulichen Ausbildung von Stahlbauten N2 - Die Theorie und Konstruktion der wichtigsten Bereiche der Stahlbautechnik werden von den Grundlagen her entwickelt und durch viele Beispiele praxisbezogen erläutert. Das Buch ist aus Vorlesungen im Grund- und Vertiefungsstudium des Bauingenieurwesens entstanden. Der Inhalt wird zum Teil systematisch, zum Teil exemplarisch dargestellt. Für Konstrukteure und Statiker in den technischen Büros, der Beratenden Ingenieure und der Prüfämter enthält das Buch aufbereitete Berechnungsverfahren und Konstruktionsvorschläge in großer Zahl. KW - Behälterbau KW - Bemessung KW - Brandschutz KW - Brückenbau KW - Festigkeitslehre Y1 - 2022 SN - 978-3-658-20510-2 U6 - http://dx.doi.org/10.1007/978-3-658-20510-2 PB - Springer Vieweg CY - Wiesbaden ET - 5. Auflage ER - TY - JOUR A1 - Falkenberg, Fabian A1 - Bott, Michael A1 - Bongaerts, Johannes A1 - Siegert, Petra T1 - Phylogenetic survey of the subtilase family and a data-mining-based search for new subtilisins from Bacillaceae JF - Frontiers in Microbiology N2 - The subtilase family (S8), a member of the clan SB of serine proteases are ubiquitous in all kingdoms of life and fulfil different physiological functions. Subtilases are divided in several groups and especially subtilisins are of interest as they are used in various industrial sectors. Therefore, we searched for new subtilisin sequences of the family Bacillaceae using a data mining approach. The obtained 1,400 sequences were phylogenetically classified in the context of the subtilase family. This required an updated comprehensive overview of the different groups within this family. To fill this gap, we conducted a phylogenetic survey of the S8 family with characterised holotypes derived from the MEROPS database. The analysis revealed the presence of eight previously uncharacterised groups and 13 subgroups within the S8 family. The sequences that emerged from the data mining with the set filter parameters were mainly assigned to the subtilisin subgroups of true subtilisins, high-alkaline subtilisins, and phylogenetically intermediate subtilisins and represent an excellent source for new subtilisin candidates. Y1 - 2022 U6 - http://dx.doi.org/10.3389/fmicb.2022.1017978 SN - 1664-302X VL - 2022 IS - 13 PB - Frontiers CY - Lausanne ER - TY - BOOK A1 - Lauth, Jakob T1 - Physikalische Chemie kompakt KW - Physikalische Chemie Y1 - 2022 SN - 978-3-662-64587-1 U6 - http://dx.doi.org/https://doi.org/10.1007/978-3-662-64588-8 PB - Springer Spektrum CY - Berlin ER - TY - CHAP A1 - Fabo, Sabine T1 - Plüschviren – Zur Konstruktion von Nähe in Zeiten der Pandemie T2 - Interaktion – Emotion – Desinfektion ; Kunst und Museum in Zeiten von Corona / Birgit Richard, Jana Müller, Niklas von Reischach (Hrsg.) Y1 - 2022 SN - 978-3-593-51520-5 (Print) SN - 978-3-593-44960-9 (E-Book) SP - 45 EP - 69 PB - Campus CY - Frankfurt ; New York ER - TY - CHAP A1 - Gkatzogias, Konstantinos A1 - Veljkoviv, Ana A1 - Pohoryles, Daniel A. A1 - Tsionis, Georgios A1 - Bournas, Dionysios A. A1 - Crowley, Helen A1 - Norlén, Hedvig A1 - Butenweg, Christoph A1 - Gervasio, Helena A1 - Manfredi, Vincenzo A1 - Masi, Angelo A1 - Zaharieva, Roumiana ED - Gkatzogias, Konstantinos ED - Tsionis, Georgios T1 - Policy practice and regional impact assessment for building renovation T2 - REEBUILD Integrated Techniques for the Seismic Strengthening & Energy Efficiency of Existing Buildings N2 - The work presented in this report provides scientific support to building renovation policies in the EU by promoting a holistic point of view on the topic. Integrated renovation can be seen as a nexus between European policies on disaster resilience, energy efficiency and circularity in the building sector. An overview of policy measures for the seismic and energy upgrading of buildings across EU Member States identified only a few available measures for combined upgrading. Regulatory framework, financial instruments and digital tools similar to those for energy renovation, together with awareness and training may promote integrated renovation. A framework for regional prioritisation of building renovation was put forward, considering seismic risk, energy efficiency, and socioeconomic vulnerability independently and in an integrated way. Results indicate that prioritisation of building renovation is a multidimensional problem. Depending on priorities, different integrated indicators should be used to inform policies and accomplish the highest relative or most spread impact across different sectors. The framework was further extended to assess the impact of renovation scenarios across the EU with a focus on priority regions. Integrated renovation can provide a risk-proofed, sustainable, and inclusive built environment, presenting an economic benefit in the order of magnitude of the highest benefit among the separate interventions. Furthermore, it presents the unique capability of reducing fatalities and energy consumption at the same time and, depending on the scenario, to a greater extent. Y1 - 2022 SN - 978-92-76-60454-9 U6 - http://dx.doi.org/10.2760/883122 SN - 1831-9424 SP - 1 EP - 68 PB - Publications Office of the European Union CY - Luxembourg ER - TY - JOUR A1 - Funke, Harald A1 - Esch, Thomas A1 - Roosen, Petra T1 - Powertrain Adaptions for LPG Usage in General Aviation JF - MTZ worldwide N2 - In general aviation, too, it is desirable to be able to operate existing internal combustion engines with fuels that produce less CO₂ than Avgas 100LL being widely used today It can be assumed that, in comparison, the fuels CNG, LPG or LNG, which are gaseous under normal conditions, produce significantly lower emissions. Necessary propulsion system adaptations were investigated as part of a research project at Aachen University of Applied Sciences. Y1 - 2022 U6 - http://dx.doi.org/10.1007/s38313-021-0756-6 VL - 2022 IS - 83 SP - 58 EP - 62 PB - Springer Nature CY - Basel ER - TY - JOUR A1 - Engelmann, Ulrich M. A1 - Pourshahidi, Mohammad Ali A1 - Shalaby, Ahmed A1 - Krause, Hans-Joachim T1 - Probing particle size dependency of frequency mixing magnetic detection with dynamic relaxation simulation JF - Journal of Magnetism and Magnetic Materials N2 - Biomedical applications of magnetic nanoparticles (MNP) fundamentally rely on the particles’ magnetic relaxation as a response to an alternating magnetic field. The magnetic relaxation complexly depends on the interplay of MNP magnetic and physical properties with the applied field parameters. It is commonly accepted that particle core size is a major contributor to signal generation in all the above applications, however, most MNP samples comprise broad distribution spanning nm and more. Therefore, precise knowledge of the exact contribution of individual core sizes to signal generation is desired for optimal MNP design generally for each application. Specifically, we present a magnetic relaxation simulation-driven analysis of experimental frequency mixing magnetic detection (FMMD) for biosensing to quantify the contributions of individual core size fractions towards signal generation. Applying our method to two different experimental MNP systems, we found the most dominant contributions from approx. 20 nm sized particles in the two independent MNP systems. Additional comparison between freely suspended and immobilized MNP also reveals insight in the MNP microstructure, allowing to use FMMD for MNP characterization, as well as to further fine-tune its applicability in biosensing. Y1 - 2022 U6 - http://dx.doi.org/10.1016/j.jmmm.2022.169965 SN - 0304-8853 VL - 563 IS - In progress, Art. No. 169965 PB - Elsevier CY - Amsterdam ER - TY - THES A1 - Bortmann, Alevtina T1 - Produktion eines „Corporate Identity“- Werbefilms für ein IoT Technologieunternehmen N2 - Mit einem Werbefilm kann man seine Zielgruppe schnell und einfach in wenigen Minuten erreichen, indem man sich als Unternehmen auf eine freundliche Art und Weise vorstellt und somit Vertrauen und Kontakt zu der Zielgruppe herstellt. Außerdem bietet ein Werbefilm eine gute Möglichkeit sein Unternehmen als modernes und leistungsstarkes Unternehmen zu präsentieren, um potenzielle Kunden oder sogar neue Mitarbeiter zu werben. Mit einem überzeugendem Werbefilm, der richtigen Musik und Animation, bleibt ein Werbefilm im Gedächtnis der Zuschauer, viel besser als es Printwerbung in Form von einem Flyer oder einer Broschüre erfüllen kann. Zusätzlich kann man seine Reichweite im Social-Media Bereich um weitere Kanäle erweitern. Dies wiederum ermöglicht dem Unternehmen seinen Kundenstamm zu stärken und auszubauen. KW - CI KW - Werbefilm KW - Video KW - Corporate Identity KW - IT Y1 - 2022 PB - FH Aachen CY - Aachen ER - TY - CHAP A1 - Striebing, Clemens A1 - Müller, Jörg A1 - Schraudner, Martina A1 - Gewinner, Irina Valerie A1 - Guerrero Morales, Patricia A1 - Hochfeld, Katharina A1 - Hoffman, Shekinah A1 - Kmec, Julie A. A1 - Nguyen, Huu Minh A1 - Schneider, Jannick A1 - Sheridan, Jennifer A1 - Steuer-Dankert, Linda A1 - Trimble O'Connor, Lindsey A1 - Vandevelde-Rougale, Agnès T1 - Promoting diversity and combatting discrimination in research organizations: a practitioner’s guide T2 - Diversity and discrimination in research organizations N2 - The essay is addressed to practitioners in research management and from academic leadership. It describes which measures can contribute to creating an inclusive climate for research teams and preventing and effectively dealing with discrimination. The practical recommendations consider the policy and organizational levels, as well as the individual perspective of research managers. Following a series of basic recommendations, six lessons learned are formulated, derived from the contributions to the edited collection on “Diversity and Discrimination in Research Organizations.” KW - Inclusive work climate KW - lessons learned KW - policy recommendations KW - recommendations for actions KW - bullying Y1 - 2022 SN - 978-1-80117-959-1 (Print) SN - 978-1-80117-956-0 (Online) U6 - http://dx.doi.org/10.1108/978-1-80117-956-020221012 SP - 421 EP - 442 PB - Emerald Publishing Limited CY - Bingley ER - TY - JOUR A1 - Coll-Perales, Baldomero A1 - Schulte-Tigges, Joschua A1 - Rondinone, Michele A1 - Gozalvez, Javier A1 - Reke, Michael A1 - Matheis, Dominik A1 - Walter, Thomas T1 - Prototyping and evaluation of infrastructure-assisted transition of control for cooperative automated vehicles JF - IEEE Transactions on Intelligent Transportation Systems N2 - Automated driving is now possible in diverse road and traffic conditions. However, there are still situations that automated vehicles cannot handle safely and efficiently. In this case, a Transition of Control (ToC) is necessary so that the driver takes control of the driving. Executing a ToC requires the driver to get full situation awareness of the driving environment. If the driver fails to get back the control in a limited time, a Minimum Risk Maneuver (MRM) is executed to bring the vehicle into a safe state (e.g., decelerating to full stop). The execution of ToCs requires some time and can cause traffic disruption and safety risks that increase if several vehicles execute ToCs/MRMs at similar times and in the same area. This study proposes to use novel C-ITS traffic management measures where the infrastructure exploits V2X communications to assist Connected and Automated Vehicles (CAVs) in the execution of ToCs. The infrastructure can suggest a spatial distribution of ToCs, and inform vehicles of the locations where they could execute a safe stop in case of MRM. This paper reports the first field operational tests that validate the feasibility and quantify the benefits of the proposed infrastructure-assisted ToC and MRM management. The paper also presents the CAV and roadside infrastructure prototypes implemented and used in the trials. The conducted field trials demonstrate that infrastructure-assisted traffic management solutions can reduce safety risks and traffic disruptions. KW - Automated driving KW - automated vehicles KW - connected automated vehicles KW - CAV KW - experimental evaluation Y1 - 2021 U6 - http://dx.doi.org/10.1109/TITS.2021.3061085 SN - 1524-9050 (Print) SN - 1558-0016 (Online) VL - 23 IS - 7 SP - 6720 EP - 6736 PB - IEEE ER - TY - THES A1 - Nordmann, Alexander T1 - Prozessüberwachung beim Werkzeugschleifen von WC-Co Hartmetallschaftfräsern Y1 - 2022 PB - FH Aachen CY - Aachen ER - TY - CHAP A1 - Schopen, Oliver A1 - Shabani, Bahman A1 - Esch, Thomas A1 - Kemper, Hans A1 - Shah, Neel ED - Rahim, S.A. ED - As'arry, A. ED - Zuhri, M.Y.M. ED - Harmin, M.Y. ED - Rezali, K.A.M. ED - Hairuddin, A.A. T1 - Quantitative evaluation of health management designs for fuel cell systems in transport vehicles T2 - 2nd UNITED-SAIG International Conference Proceedings N2 - Focusing on transport vehicles, mainly with regard to aviation applications, this paper presents compilation and subsequent quantitative evaluation of methods aimed at building an optimum integrated health management solution for fuel cell systems. The methods are divided into two different main types and compiled in a related scheme. Furthermore, different methods are analysed and evaluated based on parameters specific to the aviation context of this study. Finally, the most suitable method for use in fuel cell health management systems is identified and its performance and suitability is quantified. KW - aviation application KW - health management systems KW - fuel cell systems Y1 - 2022 N1 - 2nd UNITED-SAIG International Conference, 23-24 May 2022, Putrajaya, Malaysia SP - 1 EP - 3 ER - TY - JOUR A1 - Monakhova, Yulia A1 - Soboleva, Polina M. A1 - Fedotova, Elena S. A1 - Musina, Kristina T. A1 - Burmistrova, Natalia A. T1 - Quantum chemical calculations of IR spectra of heparin disaccharide subunits JF - Computational and Theoretical Chemistry N2 - Heparin is a natural polysaccharide, which plays essential role in many biological processes. Alterations in building blocks can modify biological roles of commercial heparin products, due to significant changes in the conformation of the polymer chain. The variability structure of heparin leads to difficulty in quality control using different analytical methods, including infrared (IR) spectroscopy. In this paper molecular modelling of heparin disaccharide subunits was performed using quantum chemistry. The structural and spectral parameters of these disaccharides have been calculated using RHF/6-311G. In addition, over-sulphated chondroitin sulphate disaccharide was studied as one of the most widespread contaminants of heparin. Calculated IR spectra were analyzed with respect to specific structure parameters. IR spectroscopic fingerprint was found to be sensitive to substitution pattern of disaccharide subunits. Vibrational assignments of calculated spectra were correlated with experimental IR spectral bands of native heparin. Chemometrics was used to perform multivariate analysis of simulated spectral data. KW - IR spectroscopy KW - Chemometrics KW - Quantum chemistry KW - Molecular modelling KW - Quality control Y1 - 2022 SN - 2210-271X U6 - http://dx.doi.org/10.1016/j.comptc.2022.113891 VL - 1217 IS - Article number: 113891 PB - Elsevier CY - New York, NY ER - TY - THES A1 - Scholl, Lisa A1 - Stolle, Jana T1 - Raising the bar for chronic care : a digital tool to support the self-management of chronic conditions N2 - Nahezu jede:r zweite Deutsche ist chronisch krank – Tendenz steigend. Damit gehören chronische Krankheiten laut RKI zu den häufigsten und bedeutsamsten Gesundheitsproblemen weltweit. Für Betroffene bedeutet eine chronische Erkrankung je nach Schweregrad eine Einschränkung im Alltag sowie verringerte Lebensqualität. Die Health App »nomi« greift die Herausforderungen dieser Menschen auf und revolutioniert die Beobachtung ihrer Symptome und Faktoren. Das schnelle, flexible Tracking wird von Wearables ermöglicht. Durch den Vergleich von Faktoren werden Zusammenhänge abgebildet und das eigene Verständnis der Erkrankung gefördert. Darüber hinaus können diese Daten in Form von Berichten für Ärzt:innen freigegeben werden und bieten somit eine authentische Einsicht in den Krankheitsverlauf. Individuelle Routinen und Erinnerungen fördern das Selbstmanagement. Somit steigert „nomi“ langfristig die Lebensqualität Betroffener – als zuverlässiger Begleiter. KW - UX Design KW - UI Design KW - Gesundheit KW - Gesundheitspflege KW - Chronische Krankheiten Y1 - 2022 PB - FH Aachen CY - Aachen ER - TY - CHAP A1 - Chavez Bermudez, Victor Francisco A1 - Cruz Castanon, Victor Fernando A1 - Ruchay, Marco A1 - Wollert, Jörg ED - Leipzig, Hochschule für Technik, Wirtschaft und Kultur T1 - Rapid prototyping framework for automation applications based on IO-Link T2 - Tagungsband AALE 2022 N2 - The development of protype applications with sensors and actuators in the automation industry requires tools that are independent of manufacturer, and are flexible enough to be modified or extended for any specific requirements. Currently, developing prototypes with industrial sensors and actuators is not straightforward. First of all, the exchange of information depends on the industrial protocol that these devices have. Second, a specific configuration and installation is done based on the hardware that is used, such as automation controllers or industrial gateways. This means that the development for a specific industrial protocol, highly depends on the hardware and the software that vendors provide. In this work we propose a rapid-prototyping framework based on Arduino to solve this problem. For this project we have focused to work with the IO-Link protocol. The framework consists of an Arduino shield that acts as the physical layer, and a software that implements the IO-Link Master protocol. The main advantage of such framework is that an application with industrial devices can be rapid-prototyped with ease as its vendor independent, open-source and can be ported easily to other Arduino compatible boards. In comparison, a typical approach requires proprietary hardware, is not easy to port to another system and is closed-source. KW - Rapid-prototyping KW - Arduino KW - IO-Link KW - Industrial Communication Y1 - 2022 SN - 978-3-910103-00-9 U6 - http://dx.doi.org/10.33968/2022.28 N1 - 18. AALE-Konferenz, Pforzheim, 09.03.-11.03.2022. CY - Leipzig ER - TY - BOOK A1 - Kurz, Melanie A1 - Schwer, Thilo T1 - Raster, Regeln, Ratio : Systematiken und Normungen im Design des 20. Jahrhunderts / herausgegeben von Melanie Kurz und Thilo Schwer T3 - Schriften / Gesellschaft für Designgeschichte Y1 - 2022 SN - 978-3-89986-380-2 N1 - Band 5 PB - avedition CY - Stuttgart ER - TY - JOUR A1 - Röthenbacher, Annika A1 - Cesari, Matteo A1 - Doppler, Christopher E.J. A1 - Okkels, Niels A1 - Willemsen, Nele A1 - Sembowski, Nora A1 - Seger, Aline A1 - Lindner, Marie A1 - Brune, Corinna A1 - Stefani, Ambra A1 - Högl, Birgit A1 - Bialonski, Stephan A1 - Borghammer, Per A1 - Fink, Gereon R. A1 - Schober, Martin A1 - Sommerauer, Michael T1 - RBDtector: an open-source software to detect REM sleep without atonia according to visual scoring criteria JF - Scientific Reports N2 - REM sleep without atonia (RSWA) is a key feature for the diagnosis of rapid eye movement (REM) sleep behaviour disorder (RBD). We introduce RBDtector, a novel open-source software to score RSWA according to established SINBAR visual scoring criteria. We assessed muscle activity of the mentalis, flexor digitorum superficialis (FDS), and anterior tibialis (AT) muscles. RSWA was scored manually as tonic, phasic, and any activity by human scorers as well as using RBDtector in 20 subjects. Subsequently, 174 subjects (72 without RBD and 102 with RBD) were analysed with RBDtector to show the algorithm’s applicability. We additionally compared RBDtector estimates to a previously published dataset. RBDtector showed robust conformity with human scorings. The highest congruency was achieved for phasic and any activity of the FDS. Combining mentalis any and FDS any, RBDtector identified RBD subjects with 100% specificity and 96% sensitivity applying a cut-off of 20.6%. Comparable performance was obtained without manual artefact removal. RBD subjects also showed muscle bouts of higher amplitude and longer duration. RBDtector provides estimates of tonic, phasic, and any activity comparable to human scorings. RBDtector, which is freely available, can help identify RBD subjects and provides reliable RSWA metrics. Y1 - 2022 U6 - http://dx.doi.org/10.1038/s41598-022-25163-9 SN - 2045-2322 VL - 12 IS - Article number: 20886 SP - 1 EP - 14 PB - Springer Nature CY - London ER -