TY  - JOUR
A1  - Khodaverdi, M.
A1  - Pauly, F.
A1  - Schroder, G.
A1  - Ziemons, Karl
A1  - Sievering, R.
A1  - Halling, H.
T1  - Preliminary studies of a micro-CT for a combined small animal PET/CT scanner
JF  - 2001 IEEE Nuclear Science Symposium Conference Record, Vol. 3
N2  - We are developing an X-ray computed tomography (CT) system which will be combined with a high resolution animal PET system. This permits acquisition of both molecular and anatomical images in a single machine. In particular the CT will also be utilized for the quantification of the animal PET data by providing accurate data for attenuation correction. A first prototype has been built using a commercially available plane silicon diode detector. A cone-beam reconstruction provides the images using the Feldkamp algorithm. First measurements with this system have been performed on a mouse. It could be shown that the CT setup fulfils all demands for a high quality image of the skeleton of the mouse. It is also suited for soft tissue measurements. To improve contrast and resolution and to acquire the X-ray energy further development of the system, especially the use of semiconductor detectors and iterative reconstruction algorithms are planned.
Y1  - 2002
SN  - 1082-3654
SP  - 1605
EP  - 1606
ER  - 
TY  - JOUR
A1  - Biener, Ernst
A1  - Sasse, T.
A1  - Bökers, H.
T1  - Preliminary or final capping of sanitary landfills? : Technical and economical aspects
JF  - Sardinia 99 : proceedings / Seventh International Waste Management and Landfill Symposium, [4 - 8 October 1999, S. Margherita di Pula, Cagliari, Sardinia, Italy]. Ed.: Thomas H. Christensen. -  Bd. 3 : Barriers, waste mechanics and landfill design
Y1  - 1999
N1  - International Waste Management and Landfill Symposium <7, 1999, Cagliari>
SP  - 287
EP  - 294
PB  - CISA, Environmental Sanitary Engineering Centre
CY  - Cagliari
ER  - 
TY  - JOUR
A1  - Kezerashvili, Roman Ya
A1  - Dachwald, Bernd
T1  - Preface: Solar sailing: Concepts, technology, and missions II
JF  - Advances in Space Research
Y1  - 2021
U6  - http://dx.doi.org/10.1016/j.asr.2021.01.037
SN  - 0273-1177
VL  - 67
IS  - 9
SP  - 2559
EP  - 2560
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Doll, Theodor
A1  - Wagner, Patrick
T1  - Preface / Doll, Theodor ; Wagner, Patrick ; Schöning, Michael J.
JF  - physica status solidi (a) . 206 (2009), H. 3
Y1  - 2009
SN  - 1862-6319
N1  - Special Issue: Engineering of Functional Interfaces (EnFI 08)
SP  - 389
EP  - 390
ER  - 
TY  - JOUR
A1  - Anik, Sabri
A1  - Frohberg, Martin G.
A1  - Kapoor, Madan Lal
T1  - Prediction of thermodynamic properties of oxygen in binary metallic solvents
JF  - Zeitschrift für Metallkunde
Y1  - 1983
SN  - 0044-3093
VL  - 74
IS  - 6
SP  - 372
EP  - 375
ER  - 
TY  - JOUR
A1  - Engelmann, Ulrich M.
A1  - Shasha, Carolyn
A1  - Teeman, Eric
A1  - Slabu, Iona
A1  - Krishnan, Kannan M.
T1  - Predicting size-dependent heating efficiency of magnetic nanoparticles from experiment and stochastic Néel-Brown Langevin simulation
JF  - Journal of Magnetism and Magnetic Materials
Y1  - 2019
U6  - http://dx.doi.org/10.1016/j.jmmm.2018.09.041
SN  - 0304-8853
VL  - 471
IS  - 1
SP  - 450
EP  - 456
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schelthoff, Christof
A1  - Basermann, Achim
A1  - Reichel, Björn
T1  - Preconditioned CG methods for sparse matrices on massively parallel machines / Basermann, A. ; Reichel, B. ; Schelthoff, C.
JF  - Parallel Computing. 23 (1997), H. 3
Y1  - 1997
SN  - 0167-8191
SP  - 381
EP  - 398
ER  - 
TY  - JOUR
A1  - Henken, F. E.
A1  - Oosterhuis, K.
A1  - Öhlschläger, Peter
A1  - Bosch, L.
A1  - Hooijberg, E.
A1  - Haanen, J. B. A. G.
A1  - Steenbergen, R. D. M.
T1  - Preclinical safety evaluation of DNA vaccines encoding modified HPV16 E6 and E7
JF  - Vaccine
N2  - Persistent infection with high-risk human papillomaviruses (hrHPV) can result in the formation of anogenital cancers. As hrHPV proteins E6 and E7 are required for cancer initiation and maintenance, they are ideal targets for immunotherapeutic interventions. Previously, we have described the development of DNA vaccines for the induction of HPV16 E6 and E7 specific T cell immunity. These vaccines consist of ‘gene-shuffled’ (SH) versions of HPV16 E6 and E7 that were fused to Tetanus Toxin Fragment C domain 1 (TTFC) and were named TTFC-E6SH and TTFC-E7SH. Gene-shuffling was performed to avoid the risk of inducing malignant transformation at the vaccination site. Here, we describe the preclinical safety evaluation of these candidate vaccines by analysis of their transforming capacity in vitro using established murine fibroblasts (NIH 3T3 cells) and primary human foreskin keratinocytes (HFKs). We demonstrate that neither ectopic expression of TTFC-E6SH and TTFC-E7SH alone or in combination enabled NIH 3T3 cells to form colonies in soft agar. In contrast, expression of HPV16 E6WT and E7WT alone or in combination resulted in effective transformation. Similarly, retroviral transduction of HFKs from three independent donors with both TTFC-E6SH and TTFC-E7SH alone or in combination did not show any signs of immortalization. In contrast, the combined expression of E6WT and E7WT induced immortalization in HFKs from all donors. Based on these results we consider it justified to proceed to clinical evaluation of DNA vaccines encoding TTFC-E6SH and TTFC-E7SH in patients with HPV16 associated (pre)malignancies.
Y1  - 2012
U6  - http://dx.doi.org/10.1016/j.vaccine.2012.04.013
SN  - 0264-410X
VL  - 30
IS  - 28
SP  - 4259
EP  - 4266
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Oosterhuis, Koen
A1  - Öhlschläger, Peter
A1  - Berg, Joost H. van den
A1  - Toebes, Mireille
A1  - Gomez, Raquel
A1  - Schumacher, Ton N.
A1  - Haanen, John B.
T1  - Preclinical development of highly effective and safe DNA vaccines directed against HPV 16 E6 and E7
JF  - International Journal of Cancer
Y1  - 2011
SN  - 1097-0215
VL  - 129
IS  - 2
SP  - 397
EP  - 406
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Savitskaya, Irina
A1  - Zhantlessova, Sirina
A1  - Kistaubayeva, Aida
A1  - Ignatova, Ludmila
A1  - Shokatayeva, Dina
A1  - Sinyavsky, Yuriy
A1  - Kushugulova, Almagul
A1  - Digel, Ilya
T1  - Prebiotic cellulose–pullulan matrix as a “vehicle” for probiotic biofilm delivery to the host large intestine
JF  - Polymers
N2  - This study describes the development of a new combined polysaccharide-matrix-based technology for the immobilization of Lactobacillus rhamnosus GG (LGG) bacteria in biofilm form. The new composition allows for delivering the bacteria to the digestive tract in a manner that improves their robustness compared with planktonic cells and released biofilm cells. Granules consisting of a polysaccharide matrix with probiotic biofilms (PMPB) with high cell density (>9 log CFU/g) were obtained by immobilization in the optimized nutrient medium. Successful probiotic loading was confirmed by fluorescence microscopy and scanning electron microscopy. The developed prebiotic polysaccharide matrix significantly enhanced LGG viability under acidic (pH 2.0) and bile salt (0.3%) stress conditions. Enzymatic extract of feces, mimicking colon fluid in terms of cellulase activity, was used to evaluate the intestinal release of probiotics. PMPB granules showed the ability to gradually release a large number of viable LGG cells in the model colon fluid. In vivo, the oral administration of PMPB granules in rats resulted in the successful release of probiotics in the colon environment. The biofilm-forming incubation method of immobilization on a complex polysaccharide matrix tested in this study has shown high efficacy and promising potential for the development of innovative biotechnologies.
KW  - immobilization
KW  - prebiotic
KW  - bacterial cellulose
KW  - biofilms
KW  - Lactobacillus rhamnosus GG
Y1  - 2023
U6  - http://dx.doi.org/10.3390/polym16010030
N1  - This article belongs to the Section "Polymer Composites and Nanocomposites"
IS  - 16(1)
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Gebhardt, Andreas
A1  - Schmidt, Frank-Michael
T1  - Practical experiences with making and finishing of coloured models using 3D printing
Y1  - 2002
N1  - International Conference on Rapid Prototyping and Manufacturing <2, 2002, Beijing>
ER  - 
TY  - JOUR
A1  - Funke, Harald
A1  - Esch, Thomas
A1  - Roosen, Petra
T1  - Powertrain Adaptions for LPG Usage in General Aviation
JF  - MTZ worldwide
N2  - In general aviation, too, it is desirable to be able to operate existing internal combustion engines with fuels that produce less CO₂ than Avgas 100LL being widely used today It can be assumed that, in comparison, the fuels CNG, LPG or LNG, which are gaseous under normal conditions, produce significantly lower emissions. Necessary propulsion system adaptations were investigated as part of a research project at Aachen University of Applied Sciences.
Y1  - 2022
U6  - http://dx.doi.org/10.1007/s38313-021-0756-6
VL  - 2022
IS  - 83
SP  - 58
EP  - 62
PB  - Springer Nature
CY  - Basel
ER  - 
TY  - JOUR
A1  - Yoshinobu, T.
A1  - Ui, Y.
A1  - Iwasaki, H.
A1  - Näther, Niko
A1  - Koudelka-Hep, M.
A1  - Schöning, Michael Josef
T1  - Potentiometric imaging in a microfluidic channel
JF  - Biomedizinische Technik. 49 (2004), H. 2
Y1  - 2004
SN  - 0932-4666
SP  - 998
EP  - 999
ER  - 
TY  - JOUR
A1  - Dachwald, Bernd
A1  - Seboldt, Wolfgang
A1  - Macdonald, Malcolm
A1  - Mengali, Giovanni
A1  - Quatra, Alessandro A.
A1  - McInnes, Colin R.
A1  - Rios-Reyes, Leonel
A1  - Scheerers, Daniel J.
A1  - Wie, Bong
A1  - Görlich, Marianne
A1  - Lura, Franz
A1  - Diedrich, Benjamin
A1  - Baturkin, Volodymyr
A1  - Coverstone, Victoria L.
A1  - Leipold, Manfred
A1  - Garbe, Gregory P.
T1  - Potential Solar Sail Degradation Effects on Trajectory and Attitude Control
JF  - AIAA Guidance, Navigation and Control Conference and Exhibit - AIAA Modeling and Simulation Technologies Conference and Exhibit - AIAA Atmospheric Flight Mechanics Conference and Exhibit : [San Francisco, California, 15 - 18 August 2005 ; papers]. - (AIAA meeting papers on disc ; [10.]2005,16-17)
Y1  - 2005
SN  - 1-56347-765-3
N1  - American Institute of Aeronautics and Astronautics <Reston, Va.> ; AIAA Guidance, Navigation, and Control Conference and Exhibit <2005, San Francisco, Calif.> ; AIAA paper number: AIAA-2006-6172
Link "<a href="https://arc.aiaa.org/doi/book/10.2514/MGNC05"_blank">https://arc.aiaa.org/doi/book/10.2514/MGNC05</a>" am 15.07.2022 nachgetragen Behr
PB  - American Institute of Aeronautics and Astronautics
CY  - Reston, Va.
ER  - 
TY  - JOUR
A1  - Dachwald, Bernd
A1  - Baturkin, Volodymyr
A1  - Coverstone, Victoria L.
A1  - Dietrich, Benjamin
A1  - Garbe, Gregory P.
A1  - Görlich, Marianne
A1  - Leipold, Manfred
A1  - Lura, Franz
A1  - Macdonald, Malcolm
A1  - McInnes, Colin R.
A1  - Mengali, Giovanni
A1  - Quatra, Alessandro A.
A1  - Rios-Reyes, Leonel
A1  - Scheeres, Daniel J.
A1  - Seboldt, Wolfgang
A1  - Wie, Bong
T1  - Potential Effects of Optical Solar Sail Degradation on Interplanetary Trajectory Design
JF  - Astrodynamics 2005 : proceedings of the AAS/AIAA astrodynamics conference held August 7 - 11, 2005, South Lake Tahoe, California / ed. by Bobby G. Williams. - Pt. 3. - (Advances in the astronautical sciences ; 123,3)
Y1  - 2006
UR  - http://www.spacesailing.net/paper/200508_LakeTahoe_Dachwald+.pdf
SN  - 0-87703-527-X
N1  - Astrodynamics Conference <2005, South Lake Tahoe, Calif.> ; American Astronautical Society ; Number: AAS-05-413
SP  - 2569
EP  - 2592
PB  - Univelt
CY  - San Diego, Calif.
ER  - 
TY  - JOUR
A1  - Jayaraman, Chandrasekaran
A1  - Mummidisetty, Chaitanya Krishna
A1  - Loesch, Alexandra
A1  - Kaur, Sandi
A1  - Hoppe-Ludwig, Shenan
A1  - Staat, Manfred
A1  - Jayaraman, Arun
T1  - Postural and metabolic benefits of using a forearm support walker in older adults with impairments
JF  - Archives of Physical Medicine and Rehabilitation
Y1  - 2019
U6  - http://dx.doi.org/10.1016/j.apmr.2018.10.001
SN  - 0003-9993
VL  - Volume 100
IS  - Issue 4
SP  - 638
EP  - 647
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Kozlova, Tatiana V.
A1  - Lanzl, Ines M.
T1  - Postoperative aqueous outflow in the human eye after glaucoma filtration surgery: biofluidmechanical considerations
JF  - Biomedizinische Technik = Biomedical Engineering
Y1  - 2009
SN  - 1862-278X
VL  - 54
IS  - 1
SP  - 14
EP  - 22
PB  - -
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Cherstvy, A.
A1  - Ingebrandt, S.
A1  - Offenhäusser, A.
A1  - Schöning, Michael Josef
T1  - Possibilities and limitations of label-free detection of DNA hybridization with field-effect-based devices
JF  - Sensors and Actuators B. 111-112 (2005)
Y1  - 2005
SN  - 0925-4005
N1  - Eurosensors XVIII 2004 — The 18th European Conference on Solid-State Transducers
SP  - 470
EP  - 480
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Cherstvy, A.
A1  - Schöning, Michael Josef
T1  - Possibilities and limitations of label-free detection of DNA hybridization with field-effect based devices
JF  - Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale].
Y1  - 2004
SN  - 88-7621-282-5
N1  - Eurosensors ; (18, 2004, Roma)
SP  - 173
EP  - 176
CY  - Roma
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Lieder, R. M.
A1  - Neskakis, A
T1  - Positive parity bands in ¹⁹⁵,¹⁹⁷ Tl
JF  - Proceedings of the International Conference on Nuclear Structure : Tokyo, Sept. 5 - 10, 1977 / ed. by T. Marumori. - Journal of the Physical Society of Japan ; Vol. 44, 1978 : Suppl.
Y1  - 1978
N1  - International Conference on Nuclear Structure <1977, Tokyo>
SP  - 441
PB  - Physical Soc. of Japan
CY  - Tokyo
ER  -