TY  - JOUR
A1  - Werner, Frederik
A1  - Krumbe, Christoph
A1  - Schumacher, Katharina
A1  - Groebel, Simone
A1  - Spelthahn, Heiko
A1  - Stellberg, Michael
A1  - Wagner, Torsten
A1  - Yoshinobu, Tatsuo
A1  - Selmer, Thorsten
A1  - Keusgen, Michael
A1  - Baumann, Marcus
A1  - Schöning, Michael Josef
T1  - Determination of the extracellular acidification of Escherichia coli by a light-addressable potentiometric sensor
JF  - Physica status solidi (a) : applications and material science. 208 (2011), H. 6
Y1  - 2011
SN  - 1862-6319
SP  - 1340
EP  - 1344
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Kloock, Joachim P.
A1  - Schöning, Michael Josef
T1  - Determination of cadmium concentration and pH value in aqueous solutions by means of a handheld light-addressable potentiometric sensor (LAPS) device
JF  - Electrochemical sensor analysis / edited by S. Alegret ...
Y1  - 2007
SN  - 978-0-444-53133-9
N1  - Wilson & Wilson's comprehensive analytical chemistry ; 49
SP  - e35
EP  - e44
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Warmer, Johannes
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
A1  - Kaul, Peter
T1  - Detection of triacetone triperoxide using temperature cycled metal-oxide semiconductor gas sensors
JF  - Physica status solidi (a)
Y1  - 2015
U6  - http://dx.doi.org/10.1002/pssa.201431882
SN  - 1862-6319
VL  - 212
IS  - 6
SP  - 1289
EP  - 1298
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - CHAP
A1  - Bohrn, Ulrich
A1  - Mucha, Andreas
A1  - Werner, Frederik
A1  - Stütz, Evamaria
A1  - Bäcker, Matthias
A1  - Krumbe, Christoph
A1  - Schienle, Meinrad
A1  - Fleischer, Maximilian
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Detection of toxic chromium species in water using cellbased sensor systems
Y1  - 2012
SN  - 978-3-9813484-2-2
U6  - http://dx.doi.org/10.5162/IMCS2012/P2.1.14
SP  - 1364
EP  - 1367
ER  - 
TY  - JOUR
A1  - Jablonski, Melanie
A1  - Poghossian, Arshak
A1  - Keusgen, Michael
A1  - Wege, Christina
A1  - Schöning, Michael Josef
T1  - Detection of plant virus particles with a capacitive field-effect sensor
JF  - Analytical and Bioanalytical Chemistry
N2  - Plant viruses are major contributors to crop losses and induce high economic costs worldwide. For reliable, on-site and early detection of plant viral diseases, portable biosensors are of great interest. In this study, a field-effect SiO2-gate electrolyte-insulator-semiconductor (EIS) sensor was utilized for the label-free electrostatic detection of tobacco mosaic virus (TMV) particles as a model plant pathogen. The capacitive EIS sensor has been characterized regarding its TMV sensitivity by means of constant-capacitance method. The EIS sensor was able to detect biotinylated TMV particles from a solution with a TMV concentration as low as 0.025 nM. A good correlation between the registered EIS sensor signal and the density of adsorbed TMV particles assessed from scanning electron microscopy images of the SiO2-gate chip surface was observed. Additionally, the isoelectric point of the biotinylated TMV particles was determined via zeta potential measurements and the influence of ionic strength of the measurement solution on the TMV-modified EIS sensor signal has been studied.
KW  - Plant virus
KW  - Capacitive field-effect sensor
KW  - Tobacco mosaic virus (TMV)
KW  - Label-free detection
KW  - Zeta potential
Y1  - 2021
U6  - http://dx.doi.org/10.1007/s00216-021-03448-8
SN  - 1618-2650
N1  - Corresponding authors: Arshak Poghossian & Michael J. Schöning
VL  - 413
SP  - 5669
EP  - 5678
PB  - Springer Nature
CY  - Cham
ER  - 
TY  - JOUR
A1  - Bronder, Thomas
A1  - Jessing, Max P.
A1  - Poghossian, Arshak
A1  - Keusgen, Michael
A1  - Schöning, Michael Josef
T1  - Detection of PCR-Amplified Tuberculosis DNA Fragments with Polyelectrolyte-Modified Field-Effect Sensors
JF  - Analytical Chemistry
N2  - Field-effect-based electrolyte-insulator-semiconductor (EIS) sensors were modified with a bilayer of positively charged weak polyelectrolyte (poly(allylamine hydrochloride) (PAH)) and probe single-stranded DNA (ssDNA) and are used for the detection of complementary single-stranded target DNA (cDNA) in different test solutions. The sensing mechanism is based on the detection of the intrinsic molecular charge of target cDNA molecules after the hybridization event between cDNA and immobilized probe ssDNA. The test solutions contain synthetic cDNA oligonucleotides (with a sequence of tuberculosis mycobacteria genome) or PCR-amplified DNA (which origins from a template DNA strand that has been extracted from Mycobacterium avium paratuberculosis-spiked human sputum samples), respectively. Sensor responses up to 41 mV have been measured for the test solutions with DNA, while only small signals of ∼5 mV were detected for solutions without DNA. The lower detection limit of the EIS sensors was ∼0.3 nM, and the sensitivity was ∼7.2 mV/decade. Fluorescence experiments using SybrGreen I fluorescence dye support the electrochemical results.
Y1  - 2018
U6  - http://dx.doi.org/10.1021/acs.analchem.8b01807
SN  - 0003-2700
VL  - 90
IS  - 12
SP  - 7747
EP  - 7753
PB  - ACS Publications
CY  - Washington, DC
ER  - 
TY  - JOUR
A1  - Emons, H.
A1  - Hüllenkremer, B.
A1  - Schöning, Michael Josef
T1  - Detection of metal ions in aqueous solutions by voltohmmetry
JF  - Fresenius' Journal of Analytical Chemistry. 369 (2001), H. 1
Y1  - 2001
SN  - 0937-0633
SP  - 42
EP  - 46
ER  - 
TY  - JOUR
A1  - Kassab, T.
A1  - Han, Y.
A1  - Poghossian, Arshak
A1  - Ingebrandt, S.
A1  - Offenhäusser, A.
A1  - Schöning, Michael Josef
T1  - Detection of layerby-layer adsorbed polyelectrolytes by means of field-effect based capacitive EIS structures
JF  - Biomedizinische Technik. 49 (2004), H. 2
Y1  - 2004
SN  - 0932-4666
SP  - 1034
EP  - 1035
ER  - 
TY  - JOUR
A1  - Oberländer, Jan
A1  - Kirchner, Patrick
A1  - Boyen, Hans-Gerd
A1  - Schöning, Michael Josef
T1  - Detection of hydrogen peroxide vapor by use of manganese(IV) oxide as catalyst for calorimetric gas sensors
JF  - Physica status solidi A: Applications and materials science
N2  - In this work, the catalyst manganese(IV) oxide (MnO2), of calorimetric gas sensors (to monitor the sterilization agent vaporized hydrogen peroxide) has been investigated in more detail. Chemical analyses by means of X-ray-induced photoelectron spectroscopy have been performed to unravel the surface chemistry prior and after exposure to hydrogen peroxide vapor at elevated temperature, as applied in the sterilization processes of beverage cartons. The surface characterization reveals a change in oxidation states of the metal oxide catalyst after exposure to hydrogen peroxide. Additionally, a cleaning effect of the catalyst, which itself is attached to the sensor surface by means of a polymer interlayer, could be observed.
Y1  - 2014
U6  - http://dx.doi.org/10.1002/pssa.201330359
SN  - 1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)
VL  - 211
IS  - 6
SP  - 1372
EP  - 1376
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - CHAP
A1  - Näther, Niko
A1  - Juárez, Leon M.
A1  - Emmerich, Rüdiger
A1  - Berger, Jörg
A1  - Friedrich, Peter
A1  - Schöning, Michael Josef
T1  - Detection of hydrogen peroxide (H2O2) at exposed temperatures for industrial processes
N2  - An H2O2 sensor for the application in industrial sterilisation processes has been developed. Therefore, automated sterilisation equipment at laboratory scale has been constructed using parts from industrial sterilisation facilities. In addition, a software tool has been developed for the control of the sterilisation equipment at laboratory scale. First measurements with the developed sensor set-up as part of the sterilisation equipment have been performed and the sensor has been physically characterised by optical microscopy and SEM.
KW  - Biosensor
KW  - Gas sensor
KW  - hydrogen peroxide
KW  - sterilisation
KW  - catalytic decomposition
Y1  - 2006
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-1418
ER  - 
TY  - JOUR
A1  - Herber, R.
A1  - Ernst, S.
A1  - Buß, G.
A1  - Schöning, Michael Josef
A1  - Baltruschat, H.
T1  - Detection of hydrocarbons in air and water by adsorption on Pt electrodes using continuous impedance measurements
JF  - Proceedings of the Symposium on New Directions in Electroanalytical Chemistry II : [held at the 195th Meeting of the Electrochemical Society in Seattle, Washington on May 3 and 4, 1999] / Physical Electrochemistry, Sensor, and Organic and Biological Electrochemistry Divisions. Ed.: J. Leddy, P. Vanysek, M.D. Porter
Y1  - 1999
SN  - 1-56677-227-3
N1  - Symposium on New Directions in Electroanalytical Chemistry ; (2, 1999, Seattle, Wash.)
SP  - 168
EP  - 177
PB  - Electrochemical Society
CY  - Pennington, NJ
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Poghossian, Arshak
T1  - Detection of charged macromolecules by means of field-effect devices (FEDs): possibilities and limitations
JF  - Electrochemical sensors, biosensors and their biomedical applications / ed. by Xueji Zhang ...
Y1  - 2008
SN  - 978-0-12-373738-0
SP  - 187
EP  - 212
PB  - Elsevier Acad. Press
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Molinnus, Denise
A1  - Hardt, Gabriel
A1  - Siegert, Petra
A1  - Willenberg, Holger S.
A1  - Poghossian, Arshak
A1  - Keusgen, Michael
A1  - Schöning, Michael Josef
T1  - Detection of Adrenaline in Blood Plasma as Biomarker for Adrenal Venous Sampling
JF  - Electroanalysis
N2  - An amperometric bi-enzyme biosensor based on substrate recycling principle for the amplification of the sensor signal has been developed for the detection of adrenaline in blood. Adrenaline can be used as biomarker verifying successful adrenal venous sampling procedure. The adrenaline biosensor has been realized via modification of a galvanic oxygen sensor with a bi-enzyme membrane combining a genetically modified laccase and a pyrroloquinoline quinone-dependent glucose dehydrogenase. The measurement conditions such as pH value and temperature were optimized to enhance the sensor performance. A high sensitivity and a low detection limit of about 0.5–1 nM adrenaline have been achieved in phosphate buffer at pH 7.4, relevant for measurements in blood samples. The sensitivity of the biosensor to other catecholamines such as noradrenaline, dopamine and dobutamine has been studied. Finally, the sensor has been successfully applied for the detection of adrenaline in human blood plasma.
Y1  - 2018
U6  - http://dx.doi.org/10.1002/elan.201800026
SN  - 1521-4109
VL  - 30
IS  - 5
SP  - 937
EP  - 942
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Molinnus, Denise
A1  - Bäcker, Matthias
A1  - Siegert, Petra
A1  - Willenberg, H.
A1  - Poghossian, Arshak
A1  - Keusgen, M.
A1  - Schöning, Michael Josef
T1  - Detection of Adrenaline Based on Substrate Recycling Amplification
JF  - Procedia Engineering
N2  - An amperometric enzyme biosensor has been applied for the detection of adrenaline. The adrenaline biosensor has been prepared by modification of an oxygen electrode with the enzyme laccase that operates at a broad pH range between pH 3.5 to pH 8. The enzyme molecules were immobilized via cross-linking with glutaraldehyde. The sensitivity of the developed adrenaline biosensor in different pH buffer solutions has been studied.
Y1  - 2015
U6  - http://dx.doi.org/10.1016/j.proeng.2015.08.708
SN  - 1877-7058
N1  - Eurosensors 2015
VL  - 120
SP  - 540
EP  - 543
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Molinnus, Denise
A1  - Hardt, Gabriel
A1  - Käver, Larissa
A1  - Willenberg, Holger S.
A1  - Poghossian, Arshak
A1  - Keusgen, Michael
A1  - Schöning, Michael Josef
T1  - Detection of Adrenaline Based on Bioelectrocatalytical System to Support Tumor Diagnostic Technology
T2  - MDPI Proceedings
Y1  - 2017
U6  - http://dx.doi.org/10.3390/proceedings1040506
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Detecting Both Physical and (Bio-)Chemical Parameters by Means of ISFET Devices
JF  - Electroanalysis. 16 (2004), H. 22
Y1  - 2004
SN  - 1040-0397
SP  - 1863
EP  - 1872
ER  - 
TY  - JOUR
A1  - Schusser, Sebastian
A1  - Menzel, S.
A1  - Bäcker, Matthias
A1  - Leinhos, Marcel
A1  - Poghossian, Arshak
A1  - Wagner, P.
A1  - Schöning, Michael Josef
T1  - Degradation of thin poly(lactic acid) films: characterization by capacitance-voltage, atomic force microscopy, scanning electron microscopy and contact-angle measurements
JF  - Electrochimica Acta
Y1  - 2013
SN  - 1873-3859 (E-Journal); 0013-4686 (Print)
VL  - Vol. 113
SP  - 779
EP  - 784
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Heiduschka, P.
A1  - Romann, I.
A1  - Ecken, H.
A1  - Schöning, Michael Josef
A1  - Schuhmann, W.
A1  - Thanos, S.
T1  - Defined adhesion and growth of neurones on artificial structured substrates
JF  - Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz
Y1  - 2001
SN  - 0-08-044014-2
SP  - 299
EP  - 307
PB  - Elsevier [u.a.]
CY  - Amsterdam [u.a.]
ER  - 
TY  - JOUR
A1  - Ge, B.
A1  - Meyer, T.
A1  - Schöning, Michael Josef
A1  - Wollenberger, U.
A1  - Lisdat, F., 
T1  - Cytochrome c‘ from Chromatium vinosum on gold electrodes
JF  - Electrochemistry Communications. 2 (2000), H. 8
Y1  - 2000
SN  - 1388-2481
SP  - 557
EP  - 561
ER  - 
TY  - JOUR
A1  - Thust, M.
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Naser, S.
A1  - Müller-Veggian, Mattea
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Crosssensitivity of a capacitive penicillin sensor combined with a diffusion barrier
JF  - Proceedings : The Hague, The Netherlands, September 12 - 15, 1999 / [ed. by M. Bartek]. Vol 1.
Y1  - 1999
SN  - 90-76699-02-X
N1  - Eurosensors ; (13, 1999, 's-Gravenhage) ; Eurosensors ; (13 : ; 1999.09.12-15 : ; The Hague) ; European Conference on Solid-State Transducers ; (13 : ; 1999.09.12-15 : ; The Hague)
SP  - 573
EP  - 576
CY  - The Hague, The Netherlands
ER  -