TY  - JOUR
A1  - Schroth, P.
A1  - Schöning, Michael Josef
A1  - Schütz, S.
A1  - Epanya, P.
A1  - Steffen, A.
A1  - Weißbecker, B.
A1  - Hummel, Hans E.
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Improving the bioelectronic interface of an antenna/chip biosensor – technological aspects
JF  - Proceedings : The Hague, The Netherlands, September 12 - 15, 1999 / [ed. by M. Bartek]. Vol 1.
Y1  - 1999
SN  - 90-76699-02-X
N1  - Eurosensors ; (13, 1999, 's-Gravenhage) ; Eurosensors ; (13 : ; 1999.09.12-15 : ; The Hague) ; European Conference on Solid-State Transducers ; (13 : ; 1999.09.12-15 : ; The Hague)
SP  - 569
EP  - 572
CY  - The Hague, The Netherlands
ER  - 
TY  - JOUR
A1  - Grießmeier, M.
A1  - Sonnenberg, F.
A1  - Weckesser, M.
A1  - Ziemons, Karl
A1  - Langen, K.-J.
A1  - Müller-Gärtner, H. W.
T1  - Improvement of SPECT quantification in small brain structures by using experiment based recovery-coefficient corrections
JF  - European Journal of Nuclear Medicine
Y1  - 1996
SN  - 1619-7089
N1  - Abstracts ; PSu827
VL  - 23
IS  - 9
SP  - 1238
EP  - 1238
ER  - 
TY  - JOUR
A1  - Miyamoto, Koichiro
A1  - Seki, Kosuke
A1  - Suto, Takeyuki
A1  - Werner, Frederik
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Yoshinobu, Tatsuo
T1  - Improved spatial resolution of the chemical imaging sensor with a hybrid illumination that suppresses lateral diffusion of photocarriers
JF  - Sensor and Actuators B: Chemical
N2  - The chemical imaging sensor is a semiconductor-based chemical sensor capable of visualizing pH and ion distributions. The spatial resolution depends on the lateral diffusion of photocarriers generated by illumination of the semiconductor substrate. In this study, two types of optical setups, one based on a bundle of optical fibers and the other based on a binocular tube head, were developed to project a hybrid illumination of a modulated light beam and a ring-shaped constant illumination onto the sensor plate. An improved spatial resolution was realized by the ring-shaped constant illumination, which suppressed lateral diffusion of photocarriers by enhanced recombination due to the increased carrier concentration.
Y1  - 2018
U6  - http://dx.doi.org/10.1016/j.snb.2018.07.016
SN  - 0925-4005
VL  - 273
SP  - 1328
EP  - 1333
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schäfer, Horst
A1  - Boege, P.
A1  - Shanjia, Xu
A1  - Xinzhang, Wu (u.a.)
T1  - Improved conductivity-measurement of semiconductor epitaxial layers by means of the contactless microwave method
JF  - Conference digest : 10 - 14 January 1994, San Diego, California / International Conference on Millimeter and Submillimeter Waves and Applications / Mohammed N. Afsar, chair/ed.
Y1  - 1994
SN  - 0-8194-1558-8
N1  - Serie Proceedings / SPIE, The International Society for Optical Engineering ; 2250
SP  - 649
EP  - 658
PB  - SPIE
CY  - Bellingham, Wash.
ER  - 
TY  - JOUR
A1  - Delle, Lotta E.
A1  - Huck, Christina
A1  - Bäcker, Matthias
A1  - Müller, Frank
A1  - Grandthyll, Samuel
A1  - Jacobs, Karin
A1  - Lilischkis, Rainer
A1  - Vu, Xuan T.
A1  - Schöning, Michael Josef
A1  - Wagner, Patrick
A1  - Thoelen, Roland
A1  - Weil, Maryam
A1  - Ingebrandt, Sven
T1  - Impedimetric immunosensor for the detection of histamine based on reduced graphene oxide
JF  - Physica status solidi (a)
Y1  - 2015
U6  - http://dx.doi.org/10.1002/pssa.201431863
SN  - 1862-6319
VL  - 212
IS  - 6
SP  - 1327
EP  - 1334
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Riedel, Marc
A1  - Kartchemnik, Julia
A1  - Schöning, Michael Josef
A1  - Lisdat, Fred
T1  - Impedimetric DNA detection – steps forward to sensorial application
JF  - Analytical chemistry
N2  - This study describes a label-free impedimetric sensor based on short ssDNA recognition elements for the detection of hybridization events. We concentrate on the elucidation of the influence of target length and recognition sequence position on the sensorial performance. The impedimetric measurements are performed in the presence of the redox system ferri-/ferrocyanide and show an increase in charge transfer resistance upon hybridization of ssDNA to the sensor surface. Investigations on the impedimetric signal stability demonstrate a clear influence of the buffers used during the sensor preparation and the choice of the passivating mercaptoalcanol compound. A stable sensor system has been developed, enabling a reproducible detection of 25mer target DNA in the low nanomolar range. After hybridization, a sensor regeneration can be reached with deionized water by adjustment of effective convection conditions, ensuring a sensor reusability. By investigations of longer targets with overhangs exposed to the solution, we can demonstrate applicability of the impedimetric detection for longer ssDNA. However, a decreasing charge transfer resistance change (ΔRct) is found by extending the overhang. As a strategy to increase the impedance change for longer target strands, the position of the recognition sequence can be designed in a way that a small overhang is exposed to the electrode surface. This is found to result in an increase in the relative Rct change. These results suggest that DNA and consequently negative charge near the electrode possess a larger impact on the impedimetric signal than DNA further away.
Y1  - 2014
U6  - http://dx.doi.org/10.1021/ac501800q
SN  - 1520-6882 (E-Journal); 0003-2700 (Print); 0096-4484 (Print)
VL  - 86 (2014)
IS  - 15
SP  - 7867
EP  - 7874
PB  - ACS Publications
CY  - Columbus
ER  - 
TY  - CHAP
A1  - Oberländer, Jan
A1  - Arreola, Julio
A1  - Hansen, Christina
A1  - Greeff, Anton
A1  - Mayer, Marlena
A1  - Keusgen, Michael
A1  - Schöning, Michael Josef
T1  - Impedimetric Biosensor to Enable Fast Evaluation of Gaseous Sterilization Processes
T2  - MDPI Proceedings
Y1  - 2017
U6  - http://dx.doi.org/10.3390/proceedings1040435
N1  - Eurosensors 2017 Conference, Paris, France, 3–6 September 2017
VL  - 1
IS  - 4
ER  - 
TY  - JOUR
A1  - Schusser, Sebastian
A1  - Leinhos, Marcel
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Impedance spectroscopy: A tool for real-time in situ monitoring of the degradation of biopolymers
JF  - Physica Status Solidi (A)
N2  - Investigation of the degradation kinetics of biodegradable polymers is essential for the development of implantable biomedical devices with predicted biodegradability. In this work, an impedimetric sensor has been applied for real-time and in situ monitoring of degradation processes of biopolymers. The sensor consists of two platinum thin-film electrodes covered by a polymer film to be studied. The benchmark biomedical polymer poly(D,L-lactic acid) (PDLLA) was used as a model system. PDLLA films were deposited on the sensor structure from a polymer solution by using the spin-coating method. The degradation kinetics of PDLLA films have been studied in alkaline solutions of pH 9 and 12 by means of an impedance spectroscopy (IS) method. Any changes in a polymer capacitance/resistance induced by water uptake and/or polymer degradation will modulate the global impedance of the polymer-covered sensor that can be used as an indicator of the polymer degradation. The degradation rate can be evaluated from the time-dependent impedance spectra. As expected, a faster degradation has been observed for PDLLA films exposed to pH 12 solution.
Y1  - 2013
U6  - http://dx.doi.org/10.1002/pssa.201200941
SN  - 1521-396X ; 0031-8965
VL  - 210
IS  - 5
SP  - 905
EP  - 910
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Mai, D.-T.
A1  - Mourzina, Y.
A1  - Schöning, Michael Josef
T1  - Impedance effect of an ion-sensitive membrane: characterisation of an EMIS sensor by impedance spectroscopy, capacitance-voltage and constant-capacitance method
JF  - Sensors and Actuators B. 103 (2004), H. 1-2
Y1  - 2004
SN  - 0925-4005
SP  - 423
EP  - 428
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Hekmat, K.
A1  - Zimmermann, T.
A1  - Kampe, S.
T1  - Impact of tranexamic acid vs. aprotinin on blood loss and transfusion requirements after cardiopulmonary bypass: a prospective, randomised, double-blind trial / Hekmat, K. ; Zimmermann, T. ; Kampe, S. ; Kasper, S. M. ; Weber, H. J. ; Geissler, H. J. ; Meh
JF  - Current Medical Research and Opinion. 20 (2004), H. 1
Y1  - 2004
SN  - 0300-7995
SP  - 121
EP  - 126
ER  - 
TY  - CHAP
A1  - Kahmann, Stephanie
A1  - Hackl, Michael
A1  - Wegmann, Kilian
A1  - Müller, Lars-Peter
A1  - Staat, Manfred
ED  - Erni, Daniel
T1  - Impact of a proximal radial shortening osteotomy on the distribution of forces and the stability of the elbow
T2  - 1st YRA MedTech Symposium 2016 : April 8th / 2016 / University of Duisburg-Essen
N2  - The human arm consists of the humerus (upper arm), the medial ulna and the lateral radius (forearm). The joint between the humerus and the ulna is called humeroulnar joint and the joint between the humerus and the radius is called humeroradial joint. Lateral and medial collateral ligaments stabilize the elbow. Statistically, 2.5 out of 10,000 people suffer from radial head fractures [1]. In these fractures the cartilage is often affected. Caused by the injured cartilage, degenerative diseases like posttraumatic arthrosis may occur. The resulting pain and reduced range of motion have an impact on the patient’s quality of life. Until now, there has not been a treatment which allows typical loads in daily life activities and offers good long-term results. A new surgical approach was developed with the motivation to reduce the progress of the posttraumatic arthrosis. Here, the radius is shortened by 3 mm in the proximal part [2]. By this means, the load of the radius is intended to be reduced due to a load shift to the ulna. Since the radius is the most important stabilizer of the elbow it has to be confirmed that the stability is not affected. In the first test (Fig. 1 left), pressure distributions within the humeroulnar and humeroradial joints a native and a shortened radius were measured using resistive pressure sensors (I5076 and I5027, Tekscan, USA). The humerus was loaded axially in a tension testing machine (Z010, Zwick Roell, Germany) in 50 N steps up to 400 N. From the humerus the load is transmitted through both the radius and the ulna into the hand which is fixed on the ground. In the second test (Fig. 1 right), the joint stability was investigated using a digital image correlation system to measure the displacement of the ulna. Here, the humerus is fixed with a desired flexion angle and the unconstrained forearm lies on the ground. A rope connects the load actuator with a hook fixed in the ulna. A guide roller is used so that the rope pulls the ulna horizontally when a tensile load is applied. This creates a moment about the elbow joint with a maximum value of 7.5 Nm. Measurements were performed with varying flexion angles (0°, 30°, 60°, 90°, 120°). For both tests and each measurement, seven specimens were used. Student ́s t-test was employed to determine whether the mean values of the measurements in native specimen and operated specimens differ significantly.
Y1  - 2016
U6  - http://dx.doi.org/10.17185/duepublico/40821
SP  - 7
EP  - 8
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - JOUR
A1  - Bogoyavlenskiy, A. P.
A1  - Berezin, V. E.
A1  - Ogneva, A. V.
A1  - Tolmacheva, V. P.
A1  - Digel, Ilya
A1  - Khudyakova, S. S.
T1  - Immunostimulating activity of a saponin-containing extract of Saponaria officinalis
JF  - Voprosy virusologii
Y1  - 1999
SN  - 0507-4088
VL  - 44
IS  - 5
SP  - 229
EP  - 232
ER  - 
TY  - JOUR
A1  - Mourzina, Ioulia G.
A1  - Yoshinobu, Tatsuo
A1  - Ermolenko, Yuri E.
A1  - Vlasov, Yuri G.
A1  - Schöning, Michael Josef
A1  - Iwasaki, H.
T1  - Immobilization of urease and cholinesterase on the surface of semiconductor transducer for the development of lightaddressable potentiometric sensors
JF  - Microchimica Acta. 144 (2004), H. 1-3
Y1  - 2004
SN  - 0026-3672
SP  - 41
EP  - 50
ER  - 
TY  - JOUR
A1  - Mourzina, I.G.
A1  - Yoshinobu, T.
A1  - Ermolenko, Y.E.
A1  - Vlasov, Y. G.
A1  - Schöning, Michael Josef
A1  - Iwasaki, H.
T1  - Immobilization of urease and cholinesterase on the surface of semiconductor transducer for the development of light-addressable potentiometric sensors
JF  - Technical digest of the 10th International Meeting on Chemical Sensors, July 11 - 14, 2004, Tsukuba, Japan / Japan Association of Chemical Sensors
Y1  - 2004
N1  - Chemical sensors ; 20.2004 Suppl. B. IMCS ; (10, 2004, Tsukuba) ; International Meeting on Chemical Sensors ; (10 : ; 2004.07.11-14 : ; Tsukuba)
SP  - 788
EP  - 789
PB  - Japan Association of Chemical Sensors
CY  - Fukuoka
ER  - 
TY  - JOUR
A1  - Hillen, Walter
A1  - Rupp, S.
A1  - Schiebel, U.
A1  - Zaengel, Thomas T.
T1  - Imaging performance of a selenium-based detector for high-resolution radiography
JF  - Medical Imaging III: Image Formation
Y1  - 1989
SN  - 0-8194-0125-0
N1  - Proceedings of SPIE ; 1090
SP  - 296
ER  - 
TY  - JOUR
A1  - Hillen, Walter
A1  - Schiebel, U.
A1  - Zaengel, T.
T1  - Imaging performance of a digital storage phosphor system
JF  - Medical Physics. 14 (1987), H. 5
Y1  - 1987
SN  - 0094-2405
SP  - 744
EP  - 751
ER  - 
TY  - JOUR
A1  - Philipp, Mohr
A1  - Efthimiou, Nikos
A1  - Pagano, Fiammetta
A1  - Kratochwil, Nicolaus
A1  - Pizzichemi, Marco
A1  - Tsoumpas, Charalampos
A1  - Auffray, Etiennette
A1  - Ziemons, Karl
T1  - Image reconstruction analysis for positron emission tomography with heterostructured scintillators
JF  - IEEE Transactions on Radiation and Plasma Medical Sciences
N2  - The concept of structure engineering has been proposed for exploring the next generation of radiation detectors with improved performance. A TOF-PET geometry with heterostructured scintillators with a pixel size of 3.0×3.1×15 mm3 was simulated using Monte Carlo. The heterostructures consisted of alternating layers of BGO as a dense material with high stopping power and plastic (EJ232) as a fast light emitter. The detector time resolution was calculated as a function of the deposited and shared energy in both materials on an event-by-event basis. While sensitivity was reduced to 32% for 100 μm thick plastic layers and 52% for 50 μm, the CTR distribution improved to 204±49 ps and 220±41 ps respectively, compared to 276 ps that we considered for bulk BGO. The complex distribution of timing resolutions was accounted for in the reconstruction. We divided the events into three groups based on their CTR and modeled them with different Gaussian TOF kernels. On a NEMA IQ phantom, the heterostructures had better contrast recovery in early iterations. On the other hand, BGO achieved a better contrast to noise ratio (CNR) after the 15th iteration due to the higher sensitivity. The developed simulation and reconstruction methods constitute new tools for evaluating different detector designs with complex time responses.
KW  - TOF PET
KW  - Heterostructure
KW  - Metascintillator
KW  - Multiple TOF kernels
KW  - Image Reconstruction
Y1  - 2022
U6  - http://dx.doi.org/10.1109/TRPMS.2022.3208615
SN  - 2469-7311
SN  - 2469-7303
VL  - 7
IS  - 1
SP  - 41
EP  - 51
PB  - IEEE
CY  - New York, NY
ER  - 
TY  - JOUR
A1  - Hillen, Walter
A1  - Schiebel, U.
A1  - Zaengel, T.
T1  - Image quality in selenium-based digital radiography. Schiebel, U.; Hillen, W.; Zaengel, T.
JF  - Medical Imaging
Y1  - 1986
N1  - Proceedings of SPIE ;  626
SP  - 176
ER  - 
TY  - JOUR
A1  - Miyamoto, Ko-ichiro
A1  - Sugawara, Yuri
A1  - Kanoh, Shin´ichiro
A1  - Yoshinobu, Tatsuo
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
T1  - Image correction method for the chemical imaging sensor
JF  - Sensors and Actuators B: Chemical. 144 (2010), H. 2
Y1  - 2010
N1  - 22nd International Conference on Eurosensors - Dresden, Germany, 7-10 September 2008 ; Eurosensors ; (22, 2008, Dresden)
SP  - 344
EP  - 348
ER  - 
TY  - JOUR
A1  - Bialonski, Stephan
A1  - Lehnertz, Klaus
T1  - Identifying phase synchronization clusters in spatially extended dynamical systems
JF  - Physical Review E
Y1  - 2006
U6  - http://dx.doi.org/10.1103/PhysRevE.74.051909
SN  - 2470-0053
VL  - 74
IS  - 5
SP  - 051909
ER  -