TY  - JOUR
A1  - Biselli, Manfred
A1  - Schröder, B.
A1  - Herfurth, C.
A1  - Meißner, P.
T1  - Differentiation of bone marrow cells immobilized on microcarriers in a fluidized bed reactor / Schröder, B. ; Herfurth, C. ; Meißner, P. ; Biselli, M. ; Link, H. ; Wandrey, C.
JF  - Animal cell technology : from vaccines to genetic medicine ; [Vilamoura, Portugal, May 1996] / ed. by Manuel J. T. Carrondo
Y1  - 1997
SN  - 0-7923-4321-2
SP  - 589
EP  - 593
PB  - Kluwer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Biselli, Manfred
A1  - Noll, T.
T1  - Dielectric spectroscopy in the cultivation of suspended and immobilized hybridoma cells / Noll, T.; Biselli, M.
JF  - Journal of Biotechnology. 63 (1998), H. 3
Y1  - 1998
SN  - 0168-1656
SP  - 187
EP  - 198
ER  - 
TY  - JOUR
A1  - Kowollik, S.
A1  - Schnitzler, Thomas
A1  - Biselli, Manfred
A1  - Krueger, R.
A1  - Zang, Werner
A1  - Peuscher, A.
A1  - Schillberg, S.
A1  - Fischer, R.
T1  - Die Rolle des Respirationsquotienten in der Zellkulturfermentation
JF  - Chemie Ingenieur Technik
Y1  - 2010
SN  - Chemie Ingenieur Tec
N1  - Special Issue: ProcessNet-Jahrestagung 2010 und 28. Jahrestagung der Biotechnologen
VL  - 82
IS  - 9
SP  - 1505
EP  - 1506
ER  - 
TY  - JOUR
A1  - Biselli, Manfred
A1  - Van der Pol, Jens J.
A1  - Joksch, B.
A1  - Eberhardt, R.
T1  - Development of an enzymatic multichannel flow injection analysis system for monitoring mammalian cell fermentations / Van der Pol, J.J.; Joksch, B.; Eberhardt, R.; Biselli, M.; Wandrey, C., Tramper, J.
JF  - Biosensors : fundamentals, technologies and applications ; contributions to the BMFT status seminar with international participation May, 12 to 14, 1991, Internationales Bildungs-Centrum Bogensee/Brandenburg, Germany / org. by ZIM-Zentralinstitut für Molekularbiologie, Berlin-Buch and GBF, Braunschweig. Ed. by F. Scheller
Y1  - 1992
SN  - 3527284370
N1  - GBF Monographs ; 17
SP  - 349
EP  - 352
PB  - VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Biselli, Manfred
A1  - Hambach, B.
A1  - Runstadler, P. W.
A1  - Wandrey, Christian
T1  - Development of a reactor-integrated aeration system for cultivation of animal cells in fluidized beds / Hambach, B. ; Biselli, M. ; Runstadler, P.W. ; Wandrey, C.
JF  - Animal cell technology : developments, processes, and products ; ESACT, European Society for Animal Cell Technology, the 11th meeting / Ed. R. E. Spier
Y1  - 1992
SN  - 0750604212
SP  - 381
EP  - 385
PB  - Butterworth-Heinemann
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Biselli, Manfred
A1  - Meissner, Petra
A1  - Schröder, Bernd
A1  - Herfurth, Cornelia
T1  - Development of a fixed bed bioreactor for the expansion of human hematopoietic progenitor cells / Meissner, Petra ; Schröder, Bernd ; Herfurth, Cornelia ; Biselli, Manfred
JF  - Cytotechnology. 30 (1999), H. 1
Y1  - 1999
SN  - 0920-9069
SP  - 227
EP  - 234
ER  - 
TY  - JOUR
A1  - Maggakis-Kelemen, Christina
A1  - Biselli, Manfred
A1  - Artmann, Gerhard
T1  - Determination of the elastic shear modulus of cultured human red blood cells
JF  - Biomedizinische Technik. 47 (2002), H. Suppl. 1 Pt. 1
Y1  - 2002
SN  - 0013-5585
N1  - Druckausgabe unter 63 Z 471 vorhanden
SP  - 106
EP  - 109
ER  - 
TY  - CHAP
A1  - Takenaga, Shoko
A1  - Herrera, Cony F.
A1  - Werner, Frederik
A1  - Biselli, Manfred
A1  - Schnitzler, Thomas
A1  - Schöning, Michael Josef
A1  - Öhlschläger, Peter
A1  - Wagner, Torsten
T1  - Detection of the metabolic activity of cells by differential measurements based on a single light-addressable potentiometric sensor chip
T2  - 11. Dresdner Sensor-Symposium : 9.-11.12.2013
Y1  - 2013
SN  - 978-3-9813484-5-3
SP  - 63
EP  - 67
ER  - 
TY  - PAT
A1  - Wandrey, Christian
A1  - Biselli, Manfred
A1  - Schröder, Bernd
A1  - Schmoll, Hans-Joachim
T1  - Culturing cells on macroporous glass carriers coated with gelatin, extracellular matrix protein and stromal cells
Y1  - 1999
N1  - United States Patent 5,906,940 May 25, 1999
SP  - 1
EP  - 12
ER  - 
TY  - JOUR
A1  - Schnitzler, Thomas
A1  - Biselli, Manfred
T1  - Cultivo de lineas celulares de hibridoma por CF-10H5 (DSMZ ACC477) en el BIOSTAT B plus
JF  - Noticias tecnicas del laboratorio
Y1  - 2005
VL  - 13
IS  - 3
SP  - 7
EP  - 8
ER  - 
TY  - JOUR
A1  - Biselli, Manfred
A1  - Hilbert, U.
A1  - Noll, T.
T1  - Cultivation of Human HCMV Specific Lymphocytes – An Example for  Adoptive Immunotherapy / Hilbert, U. ; Biselli, M. ; Noll, T.
JF  - Animal cell technology : from target to market ; Tylösand, Sweden, June 10 - 14, 2001 / ed. by E. Lindner-Olsson ...
Y1  - 2001
SN  - 1-4020-0264-5
N1  - Proceedings of the ... ESACT meeting ; 17
SP  - 558
EP  - 561
PB  - Kluwer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Biselli, Manfred
A1  - Noll, Thomas
A1  - Jelinek, Nanni
A1  - Schmidt, Sebastian
T1  - Cultivation of Hematopoietic Stem and Progenitor Cells: biochemical Engineering Aspects / Thomas Noll, Nanni Jelinek, Sebastian Schmidt, Manfred Biselli und Christian Wandrey
JF  - Tools and Applications of Biochemical Engineering Science
Y1  - 2002
SN  - 3-540-42250-1
N1  - Advances in Biochemical Engineering/Biotechnology. 74
SP  - 111
EP  - 128
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Bäcker, Matthias
A1  - Beging, Stefan
A1  - Biselli, Manfred
A1  - Poghossian, Arshak
A1  - Wang, J.
A1  - Zang, Werner
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Concept for a solid-state multi-parameter sensor system for cell-culture monitoring
JF  - Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI
Y1  - 2009
SN  - 0013-4686
SP  - 6107
EP  - 6112
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Biselli, Manfred
A1  - Schröder, B.
A1  - Herfurth, C.
A1  - Schmoll, H.-J.
T1  - Cocultivation of hematopoietic cells in a fluidized bed reactor / Schröder, B. ; Herfurth, C. ; Biselli, M. ; Schmoll, H.-J. ; Link, H. ; Ebell, W. ; Wandrey, C.
JF  - Animal cell technology : basic & applied aspects : proceedings of the Eighth Annual Meeting of the Japanese Association for Animal Cell Technology, Iizuka, Fukuoka, Japan, November 6-10, 1995 / edited by K. Funatsu, Y. Shirai, and T. Matsushita
Y1  - 1997
SN  - 0-7923-4486-3
N1  - Japanese Association for Animal Cell Technology. ; Meeting ; <8 ; 1995 : ; Iizuka-shi, Japan>
SP  - 137
EP  - 141
PB  - Kluwer Acad. Press
CY  - Boston
ER  - 
TY  - JOUR
A1  - Bäcker, Matthias
A1  - Rakowski, D.
A1  - Poghossian, Arshak
A1  - Biselli, Manfred
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Chip-based amperometric enzyme sensor system for monitoring of bioprocesses by flow-injection analysis
JF  - Journal of Biotechnology
N2  - A microfluidic chip integrating amperometric enzyme sensors for the detection of glucose, glutamate and glutamine in cell-culture fermentation processes has been developed. The enzymes glucose oxidase, glutamate oxidase and glutaminase were immobilized by means of cross-linking with glutaraldehyde on platinum thin-film electrodes integrated within a microfluidic channel. The biosensor chip was coupled to a flow-injection analysis system for electrochemical characterization of the sensors. The sensors have been characterized in terms of sensitivity, linear working range and detection limit. The sensitivity evaluated from the respective peak areas was 1.47, 3.68 and 0.28 μAs/mM for the glucose, glutamate and glutamine sensor, respectively. The calibration curves were linear up to a concentration of 20 mM glucose and glutamine and up to 10 mM for glutamate. The lower detection limit amounted to be 0.05 mM for the glucose and glutamate sensor, respectively, and 0.1 mM for the glutamine sensor. Experiments in cell-culture medium have demonstrated a good correlation between the glutamate, glutamine and glucose concentrations measured with the chip-based biosensors in a differential-mode and the commercially available instrumentation. The obtained results demonstrate the feasibility of the realized microfluidic biosensor chip for monitoring of bioprocesses.
Y1  - 2013
U6  - http://dx.doi.org/10.1016/j.jbiotec.2012.03.014
SN  - 0168-1656
VL  - 163
IS  - 4
SP  - 371
EP  - 376
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - PAT
A1  - Berger, Eric G.
A1  - Biselli, Manfred
A1  - Dinter, André
A1  - Eisenkrätzer, Detlef
A1  - Kiesewetter, André
A1  - Zeng, Steffen
T1  - Chinese-Hamster-Ovary-Zellen zur Produktion von Proteinen
T1  - Chinese hamster ovary cells, useful for large-scale production of recombinant proteins, especially enzymes
Y1  - 2000
N1  - DE000019847422C1 13.01.2000
EP000001121417A2 08.08.2001
WO002000022096A9 24.08.2000
SP  - 1
EP  - 6
ER  - 
TY  - JOUR
A1  - Biselli, Manfred
A1  - Rechmann, Hanrik
A1  - Friedrich, Andrea
A1  - Forouzan, Dara
T1  - Characterization of photosynthetically active duckweed ( Wolffia australiana ) in vitro culture by Respiration Activity Monitoring System (RAMOS) / Henrik Rechmann, Andrea Friedrich, Dara Forouzan, Stefan Barth, Heide Schnabl, Manfred Biselli und Robert B
JF  - Biotechnology Letters. 29 (2007), H. 6
Y1  - 2007
SN  - 0141-5492
SP  - 971
EP  - 977
ER  - 
TY  - JOUR
A1  - Biselli, Manfred
A1  - Hilbert, Ulrike
A1  - Jelinek, Nanni
A1  - Schmidt, Sebastian
T1  - Biotechnologische Aspekte der Kultivierung humaner T-Lymphozyten / Hilbert, Ulrike ; Jelinek, Nanni ; Schmidt, Sebastian ; Biselli, Manfred
JF  - Chemie Ingenieur Technik. 72 (2000), H. 7
Y1  - 2000
SN  - 1522-2640
SP  - 746
EP  - 750
ER  - 
TY  - JOUR
A1  - Biselli, Manfred
A1  - Jelinek, N.
A1  - Schmidt, S.
A1  - Noll, T.
T1  - Bioreaktoren zur Kultivierung blutbildender Zellen / Jelinek, N. ; Schmidt, S. ; Noll, T. ; Biselli, M.
JF  - Bioforum. 24 (2001), H. 6
Y1  - 2001
SN  - 0940-0079
SP  - 418
EP  - 419
ER  - 
TY  - JOUR
A1  - Biselli, Manfred
A1  - Hilbert, U.
A1  - Jelinek, N.
A1  - Schmidt, S.
T1  - Bioprocess development for the cultivation of human T-lymphocytes / Hilbert, U. ; Jelinek, N.  Schmidt, S. ; Biselli, M.
JF  - Engineering in Life Sciences. 1 (2001)
Y1  - 2001
SN  - 1618-0240
SP  - 20
EP  - 23
ER  -