TY - CHAP A1 - Kazuki, Yasuhiro A1 - Kobayashi, Kaoru A1 - Hirabayashi, Masumi A1 - Abe, Satoshi A1 - Kajitani, Naoyo A1 - Kazuki, Kanoko A1 - Takehara, Shoko A1 - Takiguchi, Masato A1 - Satoh, Daisuke A1 - Kuze, Jiro A1 - Sakuma, Tetsushi A1 - Kaneko, Takehito A1 - Mashimo, Tomoji A1 - Osamura, Minori A1 - Hashimoto, Mari A1 - Wakatsuki, Riko A1 - Hirashima, Rika A1 - Fujiwara, Ryoichi A1 - Deguchi, Tsuneo A1 - Kurihara, Atsushi A1 - Tsukazaki, Yasuko A1 - Senda, Naoto A1 - Yamamoto, Takashi A1 - Scheer, Nico A1 - Oshimura, Mitsuo T1 - Humanized UGT2 and CYP3A transchromosomic rats for improved prediction of human drug metabolism T2 - PNAS Proceedings of the National Academy of Sciences of the United States of America Y1 - 2019 U6 - http://dx.doi.org/10.1073/pnas.1808255116 SN - 1091-6490 VL - 116 IS - 8 SP - 3072 EP - 3081 ER - TY - CHAP A1 - Mataré, Victor A1 - Schiffer, Stefan A1 - Ferrein, Alexander ED - Steinbauer, Gerald ED - Ferrein, Alexander T1 - golog++ : An integrative system design T2 - CogRob 2018. Cognitive Robotics Workshop : Proceedings of the 11th Cognitive Robotics Workshop 2018 co-located with 16th International Conference on Principles of Knowledge Representation and Reasoning (KR 2018) Tempe, AZ, USA, October 27th, 2018 Y1 - 2019 SN - 1613-0073 SP - 29 EP - 35 ER - TY - CHAP A1 - Alhwarin, Faraj A1 - Ferrein, Alexander A1 - Scholl, Ingrid T1 - An Efficient Hashing Algorithm for NN Problem in HD Spaces T2 - Lecture Notes in Computer Science Y1 - 2019 SN - 978-303005498-4 U6 - http://dx.doi.org/10.1007/978-3-030-05499-1_6 N1 - 7th International Conference on Pattern Recognition Applications and Methods, ICPRAM 2018; Funchal; Portugal; 16 January 2018 through 18 January 2018; Code 222779 SP - 101 EP - 115 ER - TY - CHAP A1 - Scholl, Ingrid A1 - Bartella, Alex A1 - Moluluo, Cem A1 - Ertural, Berat A1 - Laing, Frederic A1 - Suder, Sebastian T1 - MedicVR : Acceleration and Enhancement Techniques for Direct Volume Rendering in Virtual Reality T2 - Bildverarbeitung für die Medizin 2019 : Algorithmen – Systeme – Anwendungen Y1 - 2019 SN - 978-3-658-25326-4 U6 - http://dx.doi.org/10.1007/978-3-658-25326-4_32 SP - 152 EP - 157 PB - Springer Vieweg CY - Wiesbaden ER - TY - CHAP A1 - Schildt, Philipp A1 - Marzocca, Pier A1 - Braun, Carsten A1 - Dahmann, Peter A1 - Keimer, Jona T1 - Effects of atmospheric excitation on vibration based condition monitoring methods for hybrid-electric aircraft propulsion systems T2 - AIAC 2018: 18th Australian International Aerospace Congress: HUMS - 11th Defence Science and Technology (DST) International Conference on Health and Usage Monitoring (HUMS 2019): ISSFD - 27th International Symposium on Space Flight Dynamics (ISSFD) Y1 - 2019 SN - 9781925627213 SP - 923 EP - 928 ER - TY - CHAP A1 - Schmidts, Oliver A1 - Kraft, Bodo A1 - Siebigteroth, Ines A1 - Zündorf, Albert T1 - Schema Matching with Frequent Changes on Semi-Structured Input Files: A Machine Learning Approach on Biological Product Data T2 - Proceedings of the 21st International Conference on Enterprise Information Systems - Volume 1: ICEIS Y1 - 2019 SN - 978-989-758-372-8 U6 - http://dx.doi.org/10.5220/0007723602080215 SP - 208 EP - 215 ER - TY - CHAP A1 - Hunker, Jan A1 - Jung, Alexander A1 - Goßmann, Matthias A1 - Linder, Peter A1 - Staat, Manfred ED - Staat, Manfred ED - Erni, Daniel T1 - Development of a tool to analyze the conduction speed in microelectrode array measurements of cardiac tissue T2 - 3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen N2 - The discovery of human induced pluripotent stem cells reprogrammed from somatic cells [1] and their ability to differentiate into cardiomyocytes (hiPSC-CMs) has provided a robust platform for drug screening [2]. Drug screenings are essential in the development of new components, particularly for evaluating the potential of drugs to induce life-threatening pro-arrhythmias. Between 1988 and 2009, 14 drugs have been removed from the market for this reason [3]. The microelectrode array (MEA) technique is a robust tool for drug screening as it detects the field potentials (FPs) for the entire cell culture. Furthermore, the propagation of the field potential can be examined on an electrode basis. To analyze MEA measurements in detail, we have developed an open-source tool. Y1 - 2019 SN - 978-3-940402-22-6 U6 - http://dx.doi.org/10.17185/duepublico/48750 SP - 7 EP - 8 PB - Universität Duisburg-Essen CY - Duisburg ER - TY - CHAP A1 - Raman, Aravind Hariharan A1 - Jung, Alexander A1 - Horváth, András A1 - Becker, Nadine A1 - Staat, Manfred ED - Staat, Manfred ED - Erni, Daniel T1 - Modification of a computer model of human stem cell-derived cardiomyocyte electrophysiology based on Patch-Clamp measurements T2 - 3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen N2 - Human induced pluripotent stem cells (hiPSCs) have shown to be promising in disease studies and drug screenings [1]. Cardiomyocytes derived from hiPSCs have been extensively investigated using patch-clamping and optical methods to compare their electromechanical behaviour relative to fully matured adult cells. Mathematical models can be used for translating findings on hiPSCCMs to adult cells [2] or to better understand the mechanisms of various ion channels when a drug is applied [3,4]. Paci et al. (2013) [3] developed the first model of hiPSC-CMs, which they later refined based on new data [3]. The model is based on iCells® (Fujifilm Cellular Dynamics, Inc. (FCDI), Madison WI, USA) but major differences among several cell lines and even within a single cell line have been found and motivate an approach for creating sample-specific models. We have developed an optimisation algorithm that parameterises the conductances (in S/F=Siemens/Farad) of the latest Paci et al. model (2018) [5] using current-voltage data obtained in individual patch-clamp experiments derived from an automated patch clamp system (Patchliner, Nanion Technologies GmbH, Munich). Y1 - 2019 SN - 978-3-940402-22-6 U6 - http://dx.doi.org/10.17185/duepublico/48750 SP - 10 EP - 11 PB - Universität Duisburg-Essen CY - Duisburg ER - TY - CHAP A1 - Hoffmann, Katharina A1 - Nieren, Monika A1 - Gäb, Martina A1 - Kasper, Anna A1 - Elbers, Gereon T1 - The potential of near infrared spectroscopy (NIRS) for the environmental biomonitoring of plants T2 - International conference on Life Sciences and Technology N2 - In the current environmental condition, the increase in pollution of the air, water, and soil indirectly will induce plants stress and decrease vegetation growth rate. These issues pay more attention to be solved by scientists worldwide. The higher level of chemical pollutants also induced the gradual changes in plants metabolism and decreased enzymatic activity. Importantly, environmental biomonitoring may play a pivotal contribution to prevent biodiversity degradation and plants stress due to pollutant exposure. Several previous studies have been done to monitor the effect of environmental changes on plants growth. Among that, Near Infrared spectroscopy (NIRS) offers an alternative way to observe the significant alteration of plant physiology caused by environmental damage related to pollution. Impairment of photosynthesis, nutrient and oxidative imbalances, and mutagenesis. Y1 - 2019 U6 - http://dx.doi.org/10.1088/1755-1315/276/1/012009 SN - 1755-1315 N1 - IOP Conference Series: Earth and Environmental Science : 276 VL - 276 IS - 012009 SP - 1 EP - 3 ER - TY - CHAP A1 - Ferrein, Alexander A1 - Scholl, Ingrid A1 - Neumann, Tobias A1 - Krückel, Kai A1 - Schiffer, Stefan T1 - A system for continuous underground site mapping and exploration Y1 - 2019 U6 - http://dx.doi.org/10.5772/intechopen.85859 ER - TY - CHAP A1 - Ferrein, Alexander A1 - Bharatheesha, Mukunda A1 - Schiffer, Stefan A1 - Corbato, Carlos Hernandez T1 - TRROS 2018 : Teaching Robotics with ROS Workshop at ERF 2018; Proceedings of the Workshop on Teaching Robotics with ROS (held at ERF 2018), co-located with European Robotics Forum 2018 (ERF 2018), Tampere, Finland, March 15th, 2018 T2 - CEUR Workshop Proceedings Y1 - 2019 SN - 1613-0073 IS - Vol-2329 ER - TY - CHAP A1 - Azar, Fouad A1 - Digel, Ilya ED - Staat, Manfred ED - Erni, Daniel T1 - Utilization of fluorescence spectroscopy and neural networks in clinical analysis T2 - 3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen N2 - Fluorescence topography of human urine in combination with learning algorithms can provide a variant pattern recognition method in analytical clinical chemistry and, eventually, diagnosis. Y1 - 2019 SN - 978-3-940402-22-6 U6 - http://dx.doi.org/10.17185/duepublico/48750 SP - 40 EP - 41 PB - Universität Duisburg-Essen CY - Duisburg ER - TY - CHAP A1 - Zingsheim, Jonas A1 - Grimmer, Timo A1 - Ortner, Marion A1 - Schmaderer, Christoph A1 - Hauser, Christine A1 - Kotliar, Konstantin ED - Staat, Manfred ED - Erni, Daniel T1 - Recognition of subjects with mild cognitive impairment (MCI) by the use of retinal arterial vessels. T2 - 3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen Y1 - 2019 SN - 978-3-940402-22-6 U6 - http://dx.doi.org/10.17185/duepublico/48750 SP - 36 EP - 37 PB - Universität Duisburg-Essen CY - Duisburg ER - TY - CHAP A1 - Blum, Yannik A1 - Albanna, Walid A1 - Benninghaus, Anne A1 - Kotliar, Konstantin ED - Staat, Manfred ED - Erni, Daniel T1 - Vasomotion in retinal vessels of patients presenting post hemorrhagic hydrocephalus following subarachnoid hemorrhage T2 - 3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen N2 - Clearance of blood components and fluid drainage play a crucial role in subarachnoid hemorrhage (SAH) and post hemorrhagic hydrocephalus (PHH). With the involvement of interstitial fluid (ISF) and cerebrospinal fluid (CSF), two pathways for the clearance of fluid and solutes in the brain are proposed. Starting at the level of capillaries, flow of ISF follows along the basement membranes in the walls of cerebral arteries out of the parenchyma to drain into the lymphatics and CSF [1]–[3]. Conversely, it is shown that CSF enters the parenchyma between glial and pial basement membranes of penetrating arteries [4]–[6]. Nevertheless, the involved structures and the contribution of either flow pathway to fluid balance between the subarachnoid space and interstitial space remains controversial. Low frequency oscillations in vascular tone are referred to as vasomotion and corresponding vasomotion waves are modeled as the driving force for flow of ISF out of the parenchyma [7]. Retinal vessel analysis (RVA) allows non-invasive measurement of retinal vessel vasomotion with respect to diameter changes [8]. Thus, the aim of the study is to investigate vasomotion in RVA signals of SAH and PHH patients. Y1 - 2019 SN - 978-3-940402-22-6 U6 - http://dx.doi.org/10.17185/duepublico/48750 SP - 38 EP - 39 PB - Universität Duisburg-Essen CY - Duisburg ER - TY - CHAP A1 - Siebigteroth, Ines A1 - Kraft, Bodo A1 - Schmidts, Oliver A1 - Zündorf, Albert T1 - A Study on Improving Corpus Creation by Pair Annotation T2 - Proceedings of the Poster Session of the 2nd Conference on Language, Data and Knowledge (LDK-PS 2019) Y1 - 2019 SN - 1613-0073 SP - 40 EP - 44 ER - TY - CHAP A1 - Eggert, Mathias T1 - Understanding the acceptance of smart home-based insurances T2 - Proceedings of the 27th European Conference on Information Systems (ECIS), Stockholm & Uppsala, Sweden, June 8-14, 2019 Y1 - 2019 SN - 978-1-7336325-0-8 SP - 1 EP - 15 ER - TY - CHAP A1 - Galdi, Chiara A1 - Hartung, Frank A1 - Dugelay, Jean-Luc T1 - Socrates: A database of realistic data for source camera recognition on smartphones T2 - Proceedings of the 8th International Conference on Pattern Recognition Applications and Methods - Volume 1: ICPRAM Y1 - 2019 SN - 978-989-758-351-3 U6 - http://dx.doi.org/10.5220/0007403706480655 SP - 648 EP - 655 ER - TY - CHAP A1 - Hüning, Felix T1 - Complexity for heterogeneous classes: teaching embedded systems using an open project approach T2 - Varietas delectat: Complexity is the new normality - 47th Annual Conference, Budapest, Hungary16th - 20th September 2019. SEFI 47th Annual Conference Proceedings Y1 - 2019 SN - 978-2-87352-018-2 SP - 540 EP - 549 ER - TY - CHAP A1 - Breitbach, Gerd A1 - Alexopoulos, Spiros A1 - May, Martin A1 - Teixeira Boura, Cristiano José A1 - Herrmann, Ulf T1 - Analysis of volumetric solar radiation absorbers made of wire meshes T2 - AIP Conference Proceedings Y1 - 2019 U6 - http://dx.doi.org/10.1063/1.5117521 SN - 0094243X VL - 2126 SP - 030009-1 EP - 030009-6 ER - TY - CHAP A1 - Mahdi, Zahra A1 - Rendón, Carlos A1 - Schwager, Christian A1 - Teixeira Boura, Cristiano José A1 - Herrmann, Ulf T1 - Novel concept for indirect solar-heated methane reforming T2 - AIP Conference Proceedings Y1 - 2019 U6 - http://dx.doi.org/10.1063/1.5117694 SN - 0094-243X VL - 2126 SP - 180014-1 EP - 180014-7 PB - AIP Publishing CY - Melville, NY ER -