TY  - PAT
A1  - O'Connell, Timothy
A1  - Hoven, Nina
A1  - Siegert, Petra
A1  - Maurer, Karl-Heinz
T1  - Amadoriasen in Wasch- und Reinigungsmitteln [Offenlegungsschrift]
T1  - Amadoriases in washing and cleaning products [Europäische Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2007
SP  - 1
EP  - 45
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - JOUR
A1  - Seibler, Jost
A1  - Kleinridders, Andre
A1  - Küter-Luks, Birgit
A1  - Niehaves, Sandra
A1  - Brüning, Jens C.
A1  - Schwenk, Frieder
T1  - Reversible gene knockdown in mice using a tight, inducible shRNA expression system
JF  - Nucleic Acids Research
Y1  - 2007
U6  - http://dx.doi.org/10.1093/nar/gkm122
SN  - 1362-4962
VL  - 35
IS  - 7
SP  - e54
ER  - 
TY  - JOUR
A1  - Kappler-Tanudyaya, Nathalie
A1  - Schmitt, Heike
A1  - Tippkötter, Nils
A1  - Meyer, Lina
A1  - Lenzen, Sigurd
A1  - Ulber, Roland
T1  - Combination of biotransformation and chromatography for the isolation and purification of mannoheptulose
JF  - Biotechnology Journal
N2  - Mannoheptulose is a seven-carbon sugar. It is an inhibitor of glucose-induced insulin secretion due to its ability to selectively inhibit the enzyme glucokinase. An improved procedure for mannoheptulose isolation from avocados is described in this study (based upon the original method by La Forge). The study focuses on the combination of biotransformation and downstream processing (preparative chromatography) as an efficient method to produce a pure extract of mannoheptulose. The experiments were divided into two major phases. In the first phase, several methods and parameters were compared to optimize the mannoheptulose extraction with respect to efficiency and purity. In the second phase, a mass balance of mannoheptulose over the whole extraction process was undertaken to estimate the yield and efficiency of the total extraction process. The combination of biotransformation and preparative chromatography allowed the production of a pure mannoheptulose extract. In a biological test, the sugar inhibited the glucokinase enzyme activity efficiently.
Y1  - 2007
U6  - http://dx.doi.org/10.1002/biot.200700004
SN  - 1860-7314
VL  - 2
IS  - 6
SP  - 692
EP  - 699
ER  - 
TY  - JOUR
A1  - Tippkötter, Nils
A1  - Roikaew, N.
A1  - Ulber, R.
T1  - Nitratentfernung aus Molkekonzentrat mit biotechnologischer Regeneration der Abwässer
JF  - Deutsche Milchwirtschaft
Y1  - 2007
SN  - 0012-0480
VL  - 58
IS  - 15
SP  - 540
EP  - 542
ER  - 
TY  - JOUR
A1  - Paulßen, Elisabeth
A1  - Kückmann, Theresa
A1  - Abram, Ulrich
T1  - Silver(I) Complexes of 1,3-Dialkyl-4,5-dimethylimidazol-2-ylidenes and their Use as Precursors for the Synthesis of Rhenium(V) NHC Complexes
JF  - Zeitschrift für anorganische und allgemeine Chemie : ZAAC = Journal of inorganic and general chemistry
Y1  - 2007
U6  - http://dx.doi.org/10.1002/zaac.200700021
SN  - 1521-3749
VL  - 633
IS  - 5-6
SP  - 830
EP  - 834
ER  - 
TY  - CHAP
A1  - Tippkötter, Nils
A1  - Stückmann, H.
A1  - Winkelmann, G.
A1  - Noack, U.
A1  - Beutel, S.
A1  - Scheper, T.
A1  - Ulber, R.
T1  - Optimisation of antibody-labelling of gold colloids for their application in an immunchromatographic assay for microcystin-LR
T2  - European BioPerspectives : celebrating the 25th DECHEMA annual convention of biotechnologists ; 30 May - 1 June 2007, Cologne, Germany ; book of abstracts ; abstracts, poster programme
Y1  - 2007
SP  - 126
PB  - Dechema
CY  - Frankfurt am Main
ER  - 
TY  - JOUR
A1  - Waller, Mark P.
A1  - Braun, Heiko
A1  - Hojdis, Nils
A1  - Bühl, Michael
T1  - Geometries of Second-Row Transition-Metal Complexes from Density-Functional Theory
JF  - Journal of Chemical Theory and Computation
Y1  - 2007
U6  - http://dx.doi.org/10.1021/ct700178y
SN  - 1549-9626
VL  - 3
IS  - 6
SP  - 2234
EP  - 2242
ER  - 
TY  - JOUR
A1  - Jeromin, Günter Erich
A1  - Zoor, Annegreth
T1  - A new irreversible enzyme-aided esterification method in organic solvents
JF  - Biotechnology letters. 30 (2008), H. 5
Y1  - 2008
SN  - 1573-6776
SP  - 925
EP  - 928
ER  - 
TY  - JOUR
A1  - Elbers, Gereon
A1  - Nieren, Monika
A1  - Hoffmann, Katharina
A1  - Gäb, Martina
T1  - Schnellerfassung der Wirkung von Luftschadstoffen auf Pflanzen mit der Nahinfrarotspektroskopie (NIRS). Untersuchung Ammoniak exponierter Gräser und Kräuter  / Nieren, Monika ; Hoffmann, Katharina ; Gäb, Martina ; Ooyen, Sven van ; Köllner, Barbara ; Elbe
JF  - Immissionsschutz. 13 (2008), H. 2
Y1  - 2008
SN  - 1430-9262
SP  - 82
EP  - 90
ER  - 
TY  - JOUR
A1  - Selmer, Thorsten
A1  - Pinkenburg, Olaf
T1  - Method of cloning at least one nucleic acid molecule of interest using type IIS restriction endonucleases, and corresponding cloning vectors, kits and system using type IIS restriction endonucleases / Selmer, Thorsten ; Pinkenburg, Olaf
Y1  - 2008
N1  - Patent No. WO 2008095927  	A1  	Aug 14, 2008
ER  - 
TY  - BOOK
A1  - Jeromin, Günter Erich
T1  - Organische Chemie : Ein praxisbezogenes Lehrbuch. Korr. Nachdr. der 2. Aufl.
Y1  - 2008
SN  - 3-8171-1732-9
PB  - Deutsch
CY  - Frankfurt am Main
ER  - 
TY  - PAT
A1  - Jeromin, Günter Erich
A1  - Schwarzer, Klemens
T1  - Neuer Wärmeträger für Solaranlagen : Offenlegungsschrift : DE 102007016738 A1 ; Offenlegungstag: 09.10.2008
Y1  - 2008
N1  - Volltext über Datenbank DEPATISnet: http://depatisnet.dpma.de/DepatisNet/depatisnet?action=pdf&docid=DE102007016738A1
PB  - Deutsches Patent- und Markenamt
CY  - München
ER  - 
TY  - PAT
A1  - Mang, Thomas
A1  - Krombholz, Markus
A1  - Hoffmüller, Winfried
A1  - Burchard, Theodor
T1  - Verfahren zur Herstellung von Sicherheitsfolien : Offenlegungschrift DE 102007055112 A1 ; Offenlegungstag 10.07.2008 / Krombholz, Markus ; Mang, Thomas ; Hoffmüller, Winfried ; Burchard, Theodor ; Heim, Manfred
Y1  - 2008
N1  - Volltext über Datenbank: http://publikationen.dpma.de/
PB  - Deutsches Patent- und Markenamt
CY  - München
ER  - 
TY  - PAT
A1  - Siegert, Petra
A1  - Wieland, Susanne
A1  - Engelskirchen, Julia
A1  - Merkel, Marion
A1  - Maurer, Karl-Heinz
A1  - Bessler, Cornelius
T1  - Neue Alkalische Protease aus Bacillus gibsonii und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease [Offenlegungsschrift]
T1  - Novel alkaline protease from Bacillus Gibsonii and washing and cleaning agents containing said novel alkaline protease [Europäische Patentanmeldung / US Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2008
SP  - 1
EP  - 51
PB  - Deutsches Patentamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - JOUR
A1  - Herold, Marco J.
A1  - Brandt, Jens van den
A1  - Seibler, Jost
A1  - Reichardt, Holger M.
T1  - Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats
JF  - Proceedings of the National Academy of Sciences of the United States of America
Y1  - 2008
U6  - http://dx.doi.org/10.1073/pnas.0806213105
SN  - 1091-6490
VL  - 105
IS  - 47
SP  - 18507
EP  - 18512
ER  - 
TY  - JOUR
A1  - Koch, Linda
A1  - Wunderlich, F. Thomas
A1  - Seibler, Jost
A1  - Könner, A. Christine
A1  - Hampel, Brigitte
A1  - Irlenbusch, Sigrid
A1  - Brabant, Georg
A1  - Kahn, C. Ronald
A1  - Schwenk, Frieder
A1  - Brüning, Jens C.
T1  - Central insulin action regulates peripheral glucose and fat metabolism in mice
JF  - The Journal of Clinical Investigation (JCI)
Y1  - 2008
U6  - http://dx.doi.org/10.1172/JCI31073
SN  - 1558-8238
VL  - 118
IS  - 6
SP  - 2132
EP  - 2147
ER  - 
TY  - JOUR
A1  - Christoph, Thomas
A1  - Bahrenberg, Gregor
A1  - Vry, Jean de
A1  - Englberger, Werner
A1  - Erdmann, Volker A.
A1  - Frech, Moritz
A1  - Kögel, Babette
A1  - Röhl, Thomas
A1  - Schiene, Klaus
A1  - Schröder, Wolfgang
A1  - Seibler, Jost
A1  - Kurreck, Jens
T1  - Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice
JF  - Molecular and Cellular Neuroscience
Y1  - 2008
U6  - http://dx.doi.org/10.1016/j.mcn.2007.12.006
SN  - 1044-7431
VL  - 37
IS  - 3
SP  - 579
EP  - 589
ER  - 
TY  - JOUR
A1  - Tippkötter, Nils
A1  - Deterding, A.
A1  - Ulber, Roland
T1  - Determination of acetic acid in fermentation broth by gas-diffusion technique
JF  - Engineering in Life Sciences
N2  - Due to the interfering effects of acetic acid in many fermentation processes, a gas-diffusion technique was developed for the online determination of acetic acid. The measurements were accomplished with a flow diffusion analysis (FDA) unit from the TRACE Analytics GmbH, Braunschweig, Germany. The diffusion analysis is based on the UV-absorbance of acetic acid at 205 nm. The measurement was achieved by the separation of an acceptor and a carrier stream (acidified fermentation broth) using a gas permeable polytetrafluoroethylene (PTFE) membrane, whereby broth constituents that would otherwise disturb the UV-measurement of acetic acid, are held back efficiently. Merely, the fermentation by-products, e.g. formic acid, is capable of diffusing through the membrane. While formic acid can disturb the measurement, carbon dioxide does not absorb at 205 nm. The method operates with time-dependent sample enrichment. During the analysis, a small volume of the acceptor stream is stopped for a defined time interval in the acceptor chamber. During this period, the gaseous acetic acid diffuses through the membrane and is enriched in the acceptor chamber. Subsequently after the enrichment, the acceptor stream flows through a UV-detector. The intensity of the signal is proportional to the acetic acid concentration. Online measurements in bioreactors via a sterile filtration probe have been accomplished. A linear calibration in the range of 0.5–5.0 g/L acetic acid with a relative standard deviation of <5 % was obtained. A sampling rate of 8 samples per hour was possible. The system was applied for the determination of acetic acid in E. coli fermentation broth. The instrument is easy to clean, very user-friendly and does not require any toxic or expensive reagents.
Y1  - 2008
U6  - http://dx.doi.org/10.1002/elsc.200820227
VL  - 8
IS  - 1, Special Issue: Technical Systems for the Use in Life Sciences
SP  - 62
EP  - 67
ER  - 
TY  - CHAP
A1  - Tippkötter, Nils
A1  - Schünemann, V.
A1  - Christmann, R.
A1  - Pasteur, A.
A1  - Schweizer, J.
A1  - Ulber, R.
ED  - Beckmann, Dieter
T1  - Bioaffinity Layering magnetisierbarer Mikro- und Nanopartikel
T2  - Technische Systeme für die Lebenswissenschaften : 14. Heiligenstädter Kolloquium, Heilbad Heiligenstadt, 22.09. - 24.09.2008
Y1  - 2008
SN  - 978-3-00-025695-0
SP  - 97
EP  - 98
CY  - Heiligenstadt
ER  - 
TY  - JOUR
A1  - Tippkötter, Nils
A1  - Roikaew, W.
A1  - Ulber, R.
T1  - Nitrate removal from whey concentrate with biotechnological regeneration of the waste water
JF  - European dairy magazine : EDM
Y1  - 2008
SN  - 0936-6318
IS  - 1
SP  - 30
EP  - 32
ER  -