TY - JOUR A1 - Bohrn, U. A1 - Stütz, E. A1 - Fuchs, K. A1 - Fleischer, M. A1 - Schöning, Michael Josef A1 - Wagner, P. T1 - Monitoring of irritant gas using a whole-cell-based sensor system JF - Sensors and Actuators B: Chemical N2 - Cell-based sensors for the detection of gases have long been underrepresented, due to the cellular requirement of being cultured in a liquid environment. In this work we established a cell-based gas biosensor for the detection of toxic substances in air, by adapting a commercial sensor chip (Bionas®), previously used for the measurement of pollutants in liquids. Cells of the respiratory tract (A549, RPMI 2650, V79), which survive at a gas phase in a natural context, are used as biological receptors. The physiological cell parameters acidification, respiration and morphology are continuously monitored in parallel. Ammonia was used as a highly water-soluble model gas to test the feasibility of the sensor system. Infrared measurements confirmed the sufficiency of the medium draining method. This sensor system provides a basis for many sensor applications such as environmental monitoring, building technology and public security. Y1 - 2012 U6 - https://doi.org/10.1016/j.snb.2012.05.088 SN - 0925-4005 VL - 175 SP - 208 EP - 217 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schneider, Bettina A1 - Schneider, Wilhelm T1 - Due Diligence – Grundlagen und Checkliste für KMU JF - Betriebswirtschaft im Blickpunkt N2 - Im Folgenden sollen Anlass und Inhalt einer Due Diligence erläutert werden. Im Rahmen einer Checkliste werden Beratern und Unternehmen Hinweise zu möglichen Prüfungsgebieten sowie zu vorzuhaltenden oder zu prüfenden Unterlagen gegeben. Entstanden ist die Checkliste aus der langjährigen praktischen Tätigkeit der Autoren bei einer großen Wirtschaftsprüfungsgesellschaft bzw. einer deutschen Großbank. Y1 - 2012 SN - 2191-1118 SP - 148 EP - 149 PB - IWW Institut für Wissen in der Wirtschaft CY - Nordkirchen ER - TY - JOUR A1 - Werner, Frederik A1 - Groebel, Simone A1 - Krumbe, Christoph A1 - Wagner, Torsten A1 - Selmer, Thorsten A1 - Yoshinobu, Tatsuo A1 - Baumann, Marcus A1 - Schöning, Michael Josef T1 - Nutrient concentration-sensitive microorganism-based biosensor JF - Physica Status Solidi (a) Y1 - 2012 U6 - https://doi.org/10.1002/pssa.201100801 SN - 1862-6319 VL - 209 IS - 5 SP - 900 EP - 904 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Kirchner, Patrick A1 - Reisert, Steffen A1 - Pütz, Patrick A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Characterisation of polymeric materials as passivation layer for calorimetric H2O2 gas sensors JF - Physica Status Solidi (a) N2 - Calorimetric gas sensors for monitoring the H₂O₂ concentration at elevated temperatures in industrial sterilisation processes have been presented in previous works. These sensors are built up in form of a differential set-up of a catalytically active and passive temperature-sensitive structure. Although, various types of catalytically active dispersions have been studied, the passivation layer has to be established and therefore, chemically as well as physically characterised. In the present work, fluorinated ethylene propylene (FEP), perfluoralkoxy (PFA) and epoxy-based SU-8 photoresist as temperature-stable polymeric materials have been investigated for sensor passivation in terms of their chemical inertness against H₂O₂, their hygroscopic properties as well as their morphology. The polymeric materials were deposited via spin-coating on the temperature-sensitive structure, wherein spin-coated FEP and PFA show slight agglomerates. However, they possess a low absorption of humidity due to their hydrophobic surface, whereas the SU-8 layer has a closed surface but shows a slightly higher absorption of water. All of them were inert against gaseous H₂O₂ during the characterisation in H₂O₂ atmosphere that demonstrates their suitability as passivation layer for calorimetric H₂O₂ gas sensors. Y1 - 2012 U6 - https://doi.org/10.1002/pssa.201100773 SN - 1862-6319 VL - 209 IS - 5 SP - 859 EP - 863 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Hüning, Felix T1 - Using Trench PowerMOSFETs in Linear Mode JF - Power Electronics Europe (2012) N2 - If we think about applications for modern Power MOSFETs using trench technology, running them in linear mode may not be top of the priority list. Yet there are multiple uses for Trench Power MOSFETs in linear mode. In fact, even turning the device on and off in switching applications is a form of linear operation. Also, these components can be run in linear mode to protect the device against voltage surges. This article will illustrate the factors that need to be considered for linear operation and show how Trench Power MOSFETs are suited to it. Y1 - 2012 SN - 1748-3530 SP - 27 EP - 29 PB - DFA Media CY - Tonbridge ER - TY - JOUR A1 - Martius, Alexander A1 - Mischke, Winfried T1 - Die Vernehmung des Wohnungseigentümers : wann ist der Wohnungseigentümer als Partei, wann als Zeuge zu vernehmen? JF - Zeitschrift für die Anwaltspraxis : ZAP Y1 - 2012 SN - 0936-7292 IS - Fach 7 SP - 431 EP - 434 PB - ZAP Verlag CY - Bonn ER - TY - JOUR A1 - Reisgen, Uwe A1 - Schleser, Markus A1 - Mokrov, Oleg A1 - Ahmed, Essam T1 - Statistical modeling of laser welding of DP/TRIP steel sheets JF - Optics and laser technology N2 - In this research work, a statistical analysis of the CO2 laser beam welding of dual phase (DP600)/transformation induced plasticity (TRIP700) steel sheets was done using response surface methodology. The analysis considered the effect of laser power (2–2.2 kW), welding speed (40–50 mm/s) and focus position (−1 to 0 mm) on the heat input, the weld bead geometry, uniaxial tensile strength, formability limited dome height and welding operation cost. The experimental design was based on Box–Behnken design using linear and quadratic polynomial equations for predicting the mathematical models. The results indicate that the proposed models predict the responses adequately within the limits of welding parameters being used and the welding speed is the most significant parameter during the welding process. Y1 - 2012 U6 - https://doi.org/10.1016/j.optlastec.2011.05.025 SN - 1879-2545 (E-Journal); 0030-3992 (Print); 0308-4280 (Print) VL - 44 IS - 1 SP - 92 EP - 101 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Reisgen, Uwe A1 - Schleser, Markus A1 - Mokrov, Oleg A1 - Ahmed, Essam T1 - Optimization of laser welding of DP/TRIP steel sheets using statistical approach JF - Optics and laser technology N2 - Generally, the quality of a weld joint is directly influenced by the welding input parameter settings. Selection of proper process parameters is important to obtain the desired weld bead profile and quality. In this research work, numerical and graphical optimization techniques of the CO2 laser beam welding of dual phase (DP600)/transformation induced plasticity (TRIP700) steel sheets were carried out using response surface methodology (RSM) based on Box–Behnken design. The procedure was established to improve the weld quality, increase the productivity and minimize the total operation cost by considering the welding parameters range of laser power (2–2.2 kW), welding speed (40–50 mm/s) and focus position (−1 to 0 mm). It was found that, RSM can be considered as a powerful tool in experimental welding optimization, even when the experimenter does not have a model for the process. Strong, efficient and low cost weld joints could be achieved using the optimum welding conditions. Y1 - 2012 U6 - https://doi.org/10.1016/j.optlastec.2011.06.028 SN - 1879-2545 (E-Journal); 0030-3992 (Print); 0308-4280 (Print) VL - 44 IS - 1 SP - 255 EP - 262 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Reisgen, Uwe A1 - Olschok, Simon A1 - Jakobs, Stefan A1 - Schleser, Markus A1 - Mokrov, Oleg A1 - Rossiter, Eduardo T1 - Laser beam submerged arc hybrid welding JF - Physics procedia N2 - The laser beam-submerged arc hybrid welding method originates from the knowledge that, with increasing penetration depth, the laser beam process has a tendency to pore formation in the lower weld regions. The coupling with the energy-efficient submerged-arc process improves degassing and reduces the tendency to pore formation. The high deposition rate of the SA process in combination with the laser beam process offers, providing the appropriate choice of weld preparation, the possibility of welding plates with a thickness larger than 20° mm in a single pass, and also of welding thicker plates with the double-sided single pass technique. Y1 - 2012 U6 - https://doi.org/10.1016/j.phpro.2012.10.016 SN - 1875-3892 N1 - Part of special issue "Laser assisted net shape engineering 7 (LANE 2012)" VL - 39 SP - 75 EP - 83 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Reisgen, Uwe A1 - Schleser, Markus A1 - Abdurakhmanov, Aydemir A1 - Gumenyuk, Andrey T1 - Measuring of plasma properties induced by non-vacuum electron beam welding JF - Physics of plasma N2 - Electron beam plasma measurement was realised by means of DIABEAM system invented by ISF RWTH Aachen. The Langmuir probe method is used for measurement. The relative simplicity of the method and the possibility of dispersion of high power on the probe allow its application for the investigation of high-power electron beams. The key element of the method is a rotating thin tungsten wire, which intersects the beam transversely on its axis and collects part of the current by itself. The signals, which are registered in the DIABEAM as a voltage, were taken in the form of amplitude. The conversion of the probe current into the distribution along the beam radius was realised using the Abel’s method. A voltage-current characteristic was built for the beam current. The local electron density as well as the electron temperature, the floating potential and the plasma potential were measured and calculated by means of this characteristic. Y1 - 2012 U6 - https://doi.org/10.1063/1.3675874 SN - 1089-7674 (E-Journal); 1070-664X (Print) VL - 19 IS - 1 SP - 1 EP - 7 PB - AIP Publishing CY - Melville, NY ER - TY - JOUR A1 - Reisgen, Uwe A1 - Schleser, Markus A1 - Mokrov, Oleg A1 - Zabirov, Alexander A1 - Füssel, Uwe A1 - Schnick, Michael A1 - Hertel, Martin A1 - Jaeckel, Sebastian T1 - Modellierung und Visualisierung der MSG-Lichtbogenprozesse JF - Schweissen und Schneiden : Fachzeitschrift für Schweißen und verwandte Verfahren Y1 - 2012 SN - 0036-7184 VL - 64 IS - 4 SP - 166 EP - 174 PB - DVS Verlag CY - Düsseldorf ER - TY - JOUR A1 - Scheik, Sven A1 - Schleser, Markus A1 - Reisgen, Uwe T1 - Thermisches Direktfügen von Metall und Kusntstoff: eine Alternative zur Klebtechnik JF - Adhäsion : Kleben & Dichten N2 - Im Rahmen des Exzellenzclusters „Integrative Produktionstechnik für Hochlohnländer“ der RWTHAachen University werden derzeit alternative Verfahren zur Herstellung von Metall/Kunststoff- Verbindungen untersucht. Eines davon ist das thermische Direktfügen, das eine stoffschlüssige Verbindung zwischen Kunststoff und Metall ermöglicht und ohne die Verwendung von Klebstoffen, Haftvermittlern oder mechanischen Verbindungshilfen auskommt. Y1 - 2012 U6 - https://doi.org/10.1007/s35145-012-0005-x SN - 0001-8198 (E-Journal); 0001-8198 (Print) N1 - Printausg. in der Bibliothek der FH Aachen vorhanden: 63 Z 807-2012 VL - 56 IS - 11 SP - 36 EP - 40 PB - Springer Vieweg CY - Wiesbaden ER - TY - JOUR A1 - Reisgen, Uwe A1 - Schleser, Markus A1 - Mokrov, Oleg A1 - Zabirov, Alexander A1 - Füssel, Uwe A1 - Schnick, Michael A1 - Hertel, Martin A1 - Jaeckel, Sebastian T1 - Modelling and visualisation of the GMA process JF - Welding and Cutting Y1 - 2012 SN - 1612-3433 VL - 11 IS - 4 SP - 242 EP - 249 PB - DVS Verlag CY - Düsseldorf ER - TY - JOUR A1 - Reisgen, Uwe A1 - Schleser, Markus A1 - Abdurakhmanov, Aydemir A1 - Turichin, Gleb A1 - Valdaitseva, Elena A1 - Bach, Friedrich-Wilhelm A1 - Hassel, Thomas A1 - Beniyashi, Alexander T1 - Investigation of factors influencing the formation of weld defects in non-vacuum electron beam welding JF - The Paton welding journal N2 - The influence of welding condition parameters and properties of material on formation of defects, such as humping and undercuts, in non-vacuum electron beam welding was investigated. The influence of separate welding parameters on the quality of welds was determined. Y1 - 2012 SN - 0957-798X VL - 2012 IS - 2 SP - 11 EP - 18 PB - Paton Publishing House CY - Kiev ER - TY - JOUR A1 - Hötter, Jan-Steffen A1 - Fateri, Miranda A1 - Gebhardt, Andreas T1 - Selective laser melting of metals: desktop machines open up new chances even for small companies JF - Advanced materials research N2 - Additive manufacturing (AM) of metal parts by using Selective Laser Melting (SLM) has become a powerful tool mostly in the area of automotive, aerospace engineering and others. Especially in the field of dentistry, jewelry and related branches that require individualized or even one-of-a-kind products, the direct digital manufacturing process opens up new ways of design and manufacturing. In these fields, mostly small and medium sized businesses (SME) are operating which do not have sufficient human and economic resources to invest in this technology. But to stay competitive, the application of AM can be regarded as a necessity. In this situation a new desktop machine (Realizer SLM 50) was introduced that cost about 1/3 of a shop floor SLM machine and promises small quality parts. To find out whether the machine really is an alternative for SMEs the University of Applied Science, Aachen, Germany, designed, build and optimized typical parts from the dentistry and the jewelry branches using CoCr and silver material, the latter being new with this application. The paper describes the SLM procedure and how to find and optimize the most important parameters. The test is accompanied by digital simulation in order to verify the build parameters and to plan future builds. The procedure is shown as well as the resulting parts made from CoCr and silver material. Y1 - 2012 U6 - https://doi.org/10.4028/www.scientific.net/AMR.622-623.461 SN - 1662-8985 (E-Journal); 1022-6680 (Print) VL - 622-623 SP - 461 EP - 465 PB - Trans Tech Publ. CY - Baech ER - TY - JOUR A1 - Knüppel, Mark ED - Federmann, Rudolf ED - Kußmaul, Heinz ED - Müller, Stefan T1 - Außerbilanzielle Korrekturen JF - Handbuch der Bilanzierung online Y1 - 2012 SN - 0172-0392 SP - Artikel HI 1380074 PB - Haufe CY - Freiburg ER - TY - JOUR A1 - Boettcher, Martin A1 - Haselhuhn, Angelika A1 - Jakse, Gerhard A1 - Brehmer, Bernhard A1 - Kirschner-Hermanns, Ruth T1 - Overactive bladder syndrome: an underestimated long-term problem after treatment of patients with localized prostate cancer? JF - BJU international N2 - In this study we observed courses of micturition symptoms and differentiated degrees of symptoms for each point in time while also considering the impact of bothersomeness. Our data show that not only significantly more patients who have undergone BT suffer from OAB than those who have undergone RP, but also that those affected show significantly higher values for severity of OAB symptoms throughout the whole observation period of 36 months. Our data analysis further shows that variability of OAB symptoms as well as fluctuation of severity of OAB symptoms vary to a significantly higher degree after BT than after RP. Looking only at mean figures at a given point in time clearly underestimates the underlying problem. This fact is not reflected in the literature. KW - quality of life KW - prostate cancer KW - prostatectomy KW - incontinence KW - brachytherapy Y1 - 2012 U6 - https://doi.org/10.1111/j.1464-410X.2011.10623.x SN - 1365-2176 (E-Journal); 1464-410X (E-Journal); 0007-1331 (Print); 1464-4096 (Print) VL - 109 IS - 12 SP - 1824 EP - 1830 PB - Wiley-Blackwell CY - Oxford ER - TY - JOUR A1 - Ribitsch, D. A1 - Heumann, S. A1 - Karl, W. A1 - Gerlach, J. A1 - Leber, R. A1 - Birner-Gruenberger, R. A1 - Gruber, K. A1 - Eiteljoerg, I. A1 - Remler, P. A1 - Siegert, Petra A1 - Lange, J. A1 - Maurer, Karl-Heinz A1 - Berg, G. A1 - Guebitz, G. M. A1 - Schwab, H. T1 - Extracellular serine proteases from Stenotrophomonas maltophilia: Screening, isolation and heterologous expression in E. coli JF - Journal of biotechnology N2 - A large strain collection comprising antagonistic bacteria was screened for novel detergent proteases. Several strains displayed protease activity on agar plates containing skim milk but were inactive in liquid media. Encapsulation of cells in alginate beads induced protease production. Stenotrophomonas maltophilia emerged as best performer under washing conditions. For identification of wash-active proteases, four extracellular serine proteases called StmPr1, StmPr2, StmPr3 and StmPr4 were cloned. StmPr2 and StmPr4 were sufficiently overexpressed in E. coli. Expression of StmPr1 and StmPr3 resulted in unprocessed, insoluble protein. Truncation of most of the C-terminal domain which has been identified by enzyme modeling succeeded in expression of soluble, active StmPr1 but failed in case of StmPr3. From laundry application tests StmPr2 turned out to be a highly wash-active protease at 45 °C. Specific activity of StmPr2 determined with suc-l-Ala-l-Ala-l-Pro-l-Phe-p-nitroanilide as the substrate was 17 ± 2 U/mg. In addition we determined the kinetic parameters and cleavage preferences of protease StmPr2. KW - Alginate beads KW - Stenotrophomonas maltophilia KW - Detergent protease Y1 - 2012 U6 - https://doi.org/10.1016/j.jbiotec.2011.09.025 SN - 1873-4863 (E-Journal); 0168-1656 (Print) VL - 157 IS - 1 SP - 140 EP - 147 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schmitz, Philipp A1 - Weber, Martin T1 - Buying and selling behavior of individual investors in option-like securities JF - Die Betriebswirtschaft : DBW N2 - We analyze the trading behavior of individual investors in option-like securities, namely bankissued warrants, and thus expand the growing literature of investors behavior to a new kind of securities. A unique data set from a large German discount broker gives us the opportunity to analyze the trading behavior of 1,454 investors, making 89,958 transactions in 6,724 warrants on 397 underlyings. In different logit regression, we make use of the facts that investors can speculate on rising and falling prices of the underlying with call and put warrants and that we also have information about the stock portfolios of the investors. We report several facts about the trading behavior of individual investors in warrants that are consistent with the literature on the behavior of individual investors in the stock market. The warrant investors buy calls and sell puts if the price of the underlying has decreased over the past trading days and they sell calls and buy puts if the price of the underlying has increased. That means, the investors follow negative feedback trading strategies in all four trading categories observed. In addition, we find strong evidence for the disposition effect for call as well as put warrants, which is reversed in December. The trading behavior is also influenced if the underlying reaches some exceptionally prices, e.g. highs, lows or the strike price. We show that hedging, as one natural candidate to buy puts, does not play an important role in the market for bank-issued warrants. KW - Bank-issued Warrants KW - Disposition Effect KW - Negative Feedback Trading KW - Trading Behavior KW - Individual Investors Y1 - 2012 U6 - https://doi.org/10.2139/ssrn.2055088 SN - 0342-7064 VL - 72 IS - 5 SP - 409 EP - 426 PB - Schäffer-Poeschel CY - Stuttgart ER - TY - JOUR A1 - Kirchhof, Michael A1 - Kraft, Bodo T1 - Hybrides Vorgehensmodell : Agile und klassische Methoden im Projekt passend kombinieren JF - ProjektMagazin N2 - Agil ist im Trend und immer mehr Unternehmen, die ihre Projekte bisher nach klassischen Prinzipien durchführten, denken über den Einsatz agiler Methoden nach. Doch selbst wenn die Organisation bereits beide Philosophien unterstützt, gilt für ein Projekt meist die klare Vorgabe: agil oder klassisch. Es gibt aber noch einen anderen Ansatz, mit diesen "unterschiedlichen Welten" umzugehen: Und zwar die beiden Philosophien innerhalb eines Projekts zu kombinieren. Wie dies in der Praxis aussehen und gelingen kann, zeigen Dr. Michael Kirchhof und Prof. Dr. Bodo Kraft in diesem Beitrag. Y1 - 2012 IS - 11 SP - 11 S. PB - Berleb Media CY - Taufkirchen ER -