TY - JOUR A1 - Stadler, Andreas M. A1 - Digel, Ilya A1 - Embs, Jan P. A1 - Unruh, Tobias A1 - Tehei, M. A1 - Zaccai, G. A1 - Büldt, G. A1 - Artmann, Gerhard T1 - From powder to solution : Hydration dependence of human hemoglobin dynamics correlated to body temperature JF - Biophysical Journal. 96 (2009), H. 12 Y1 - 2009 SN - 0006-3495 SP - 5073 EP - 5081 PB - Cell Press CY - Cambridge, Mass. ER - TY - JOUR A1 - Stadler, Andreas M. A1 - Embs, Jan P. A1 - Digel, Ilya A1 - Artmann, Gerhard A1 - Unruh, Tobias A1 - Büldt, Georg A1 - Zaccai, Guiseppe T1 - Cytoplasmic water and hydration layer dynamics in human red blood cells JF - Journal of the American Chemical Society. 50 (2008), H. 130 Y1 - 2008 SN - 1520-5126 SP - 16852 EP - 16853 ER - TY - CHAP A1 - Stadler, Andreas M. A1 - Embs, Jan P. A1 - Zerlin, Kay A1 - Digel, Ilya A1 - Artmann, Gerhard A1 - Zaccai, Joe A1 - Büldt, Georg T1 - Temperature transitions of hemoglobin and cytosolic water diffusion in human red blood cells : [poster] N2 - Background Hemoglobin interactions in red blood cells Hemoglobin dynamics in human red blood cells Diffusion of H2O in red blood cells KW - Erythrozyt KW - Hämoglobin KW - cytosolic water diffusion KW - hemoglobin dynamics Y1 - 2007 ER - TY - JOUR A1 - Stadler, Andreas M. A1 - Garvey, G. J. A1 - Bocahut, A. A1 - Sacquin-Mora, S. A1 - Digel, Ilya A1 - Schneider, G. J. A1 - Natali, F. A1 - Artmann, Gerhard A1 - Zaccai, G. T1 - Thermal fluctuations of haemoglobin from different species : adaptation to temperature via conformational dynamics JF - Journal of the Royal Society Interface N2 - Thermodynamic stability, configurational motions and internal forces of haemoglobin (Hb) of three endotherms (platypus, Ornithorhynchus anatinus; domestic chicken, Gallus gallus domesticus and human, Homo sapiens) and an ectotherm (salt water crocodile, Crocodylus porosus) were investigated using circular dichroism, incoherent elastic neutron scattering and coarse-grained Brownian dynamics simulations. The experimental results from Hb solutions revealed a direct correlation between protein resilience, melting temperature and average body temperature of the different species on the 0.1 ns time scale. Molecular forces appeared to be adapted to permit conformational fluctuations with a root mean square displacement close to 1.2 Å at the corresponding average body temperature of the endotherms. Strong forces within crocodile Hb maintain the amplitudes of motion within a narrow limit over the entire temperature range in which the animal lives. In fully hydrated powder samples of human and chicken, Hb mean square displacements and effective force constants on the 1 ns time scale showed no differences over the whole temperature range from 10 to 300 K, in contrast to the solution case. A complementary result of the study, therefore, is that one hydration layer is not sufficient to activate all conformational fluctuations of Hb in the pico- to nanosecond time scale which might be relevant for biological function. Coarse-grained Brownian dynamics simulations permitted to explore residue-specific effects. They indicated that temperature sensing of human and chicken Hb occurs mainly at residues lining internal cavities in the β-subunits. Y1 - 2012 U6 - https://doi.org/10.1098/rsif.2012.0364 SN - 1742-5689 VL - 9 IS - 76 SP - 2845 EP - 2855 PB - The Royal Society CY - London ER - TY - JOUR A1 - Stadler, Andreas M. A1 - Zerlin, Kay A1 - Digel, Ilya A1 - Büldt, Georg A1 - Zaccai, Guiseppe A1 - Artmann, Gerhard T1 - Dynamics and interactions of hemoglobin in red blood cells JF - Tissue Engineering Part A. 14 (2008), H. 5 Y1 - 2008 SN - 1937-3341 N1 - TERMIS EU 2008 Porto Meeting June 22–26, 2008 Porto Congress Center–Alfândega Portugal SP - 724 EP - 724 ER - TY - PAT A1 - Stadtmüller, Ralf A1 - Tippkötter, Nils A1 - Ulber, Roland T1 - A method for production of single-stranded nucleic acids [Europäische Patentanmeldung] Y1 - 2013 PB - Europäisches Patentamt CY - Den Hague ER - TY - PAT A1 - Stadtmüller, Ralf A1 - Tippkötter, Nils A1 - Ulber, Roland T1 - Method for production of single-stranded macronucleotides N2 - The invention relates to a method for production of single-stranded macronucleotides by amplifying and ligating an extended monomeric single-stranded target nucleic acid sequence (targetss) into a repetitive cluster of double-stranded target nucleic acid sequences (targetds), and subsequently cloning the construct into a vector (aptagene vector). The aptagene vector is transformed into host cells for replication of the aptagene and isolated in order to optain single-stranded target sequences (targetss). The invention also relates to single-stranded nucleic acids, produced by a method of the invention. Y1 - 2015 N1 - Patent auch unter EP2774996, EP2774996, US2017145460 und US9944966 veröffentlicht. ER - TY - JOUR A1 - Stanley, Lesley A. A1 - Horsburgh, Brian C. A1 - Ross, Jillian A1 - Scheer, Nico A1 - Wolf, C. Roland T1 - Drug transporters: Gatekeepers controlling access of xenobiotics to the cellular interior JF - Drug Metabolism Reviews Y1 - 2009 U6 - https://doi.org/10.1080/03602530802605040 SN - 1097-9883 VL - 41 IS - 1 SP - 27 EP - 65 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Stanley, Lesley A. A1 - Horsburgh, Brian C. A1 - Ross, Jillian A1 - Scheer, Nico A1 - Wolf, C. Roland T1 - Nuclear Receptors which play a pivotal role in drug disposition and chemical toxicity JF - Drug Metabolism Reviews Y1 - 2006 U6 - https://doi.org/10.1080/03602530600786232 SN - 1097-9883 VL - 38 IS - 3 SP - 515 EP - 597 ER - TY - CHAP A1 - Stark, Ralf A1 - Bartel, Sebastian A1 - Ditsche, Florian A1 - Esch, Thomas T1 - Design study of a 30kN LOX/LCH4 aerospike rocket engine for lunar lander application T2 - Aerospace Europe Conference 2023 - 10th EUCASS - 9th CEAS N2 - Based on lunar lander concept EL3, various LOX/CH4 aerospike engines were studied. A distinction was made between single and cluster configurations as well as ideal and non-ideal contour concepts. It could be shown that non-ideal aerospike engines promise a significant payload gain. Y1 - 2023 N1 - Lausanne, July 9-13, 2023 ER - TY - CHAP A1 - Stark, Ralf A1 - Rieping, Carla A1 - Esch, Thomas T1 - The impact of guide tubes on flow separation in rocket nozzles T2 - Aerospace Europe Conference 2023 - 10th EUCASS - 9th CEAS N2 - Rocket engine test facilities and launch pads are typically equipped with a guide tube. Its purpose is to ensure the controlled and safe routing of the hot exhaust gases. In addition, the guide tube induces a suction that effects the nozzle flow, namely the flow separation during transient start-up and shut-down of the engine. A cold flow subscale nozzle in combination with a set of guide tubes was studied experimentally to determine the main influencing parameters. KW - Guide Tube KW - TICTOP KW - Nozzle KW - Suction Y1 - 2023 N1 - Lausanne, July 9-13, 2023 ER - TY - JOUR A1 - Starke, Günther T1 - Welding in the century of information technology. Session 1 JF - Welding in the World. 34 (1994), H. 9 Y1 - 1994 SN - 0043-2288 SP - 1 EP - 20 ER - TY - JOUR A1 - Starke, Günther A1 - Drews, P. T1 - Development approaches for advanced control in automated arc welding Y1 - 1985 N1 - Konferenz-Einzelbericht: Automation and robotisation in welding and allied processes. International conference on automation and robotisation in welding and allied processes, Strasbourg, FR, 02.09.1985-03.09.1985 SP - 115 EP - 124 ER - TY - JOUR A1 - Starke, Günther A1 - Drews, P. T1 - Le soudage au siecle de l'informatique JF - Souder. 18 (1994), H. 6 Y1 - 1994 SN - 0246-1900 SP - 33 EP - 44 ER - TY - JOUR A1 - Starke, Günther A1 - Kuhne, A.H. A1 - Frassek, B. T1 - Components for the automated GMAW process. Bestandteile des automatischen Metall-Schutzgas-Schweissverfahrens JF - Welding Journal. 63 (1984), H. 1 Y1 - 1984 SN - 0043-2296 SP - 31 EP - 34 ER - TY - CHAP A1 - Starke, Günther A1 - Kunkel, Thomas A1 - Hahn, Daniel T1 - Flexible collaboration and control of heterogeneous mechatronic devices and systems by means of an event-driven, SOA-based automation concept T2 - 2013 IEEE International Conference on Industrial Technologies (ICIT-13) Y1 - 2013 SN - 978-1-4673-4567-5 ; 978-1-4673-4569-9 SP - 1982 EP - 1987 PB - IEEE CY - Piscataway, NJ ER - TY - JOUR A1 - Steinbauer, Gerald A1 - Ferrein, Alexander T1 - 20 Years of RoboCup JF - KI - Künstliche Intelligenz Y1 - 2016 U6 - https://doi.org/10.1007/s13218-016-0442-z SN - 1610-1987 VL - 30 IS - 3-4 SP - 221 EP - 224 PB - Springer CY - Berlin ER - TY - CHAP A1 - Steinbauer, Gerald A1 - Ferrein, Alexander T1 - CogRob 2018 : Cognitive Robotics Workshop. Proceedings of the 11th Cognitive Robotics Workshop 2018 co-located with 16th International Conference on Principles of Knowledge Representation and Reasoning (KR 2018). Tempe, AZ, USA, October 27th, 2018. T2 - CEUR workshop proceedings Y1 - 2019 SN - 1613-0073 N1 - edited by Gerald Steinbauer, Alexander Ferrein IS - Vol-2325 ER - TY - JOUR A1 - Steinseifer, Ulrich A1 - Kashefi, Ali A1 - Hormes, Marcus A1 - Schoberer, Mark A1 - Orlikowsky, Thorsten A1 - Behbahani, Mehdi A1 - Behr, Marek A1 - Schmitz-Rode, Thomas T1 - Miniaturization of ECMO Systems : Engineering Challenges and Methods JF - Artificial Organs. 33 (2009), H. 5 Y1 - 2009 SN - 1525-1594 N1 - Fifth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion Abstracts SP - A55 EP - A55 ER - TY - CHAP A1 - Stender, Michael A1 - Ritz, Thomas T1 - Modeling of business-to-business mobile commerce processes T2 - Electronic proceedings / ICPR 17, 17th International Conference on Production Research [Blacksburg, Virginia, USA, August 3 - 7, 2003] Y1 - 2003 SN - 0-9721257-3-6 CY - Blacksburg, Va. ET - CD-ROM-Ausg. ER -