TY - JOUR A1 - Probst, M. A1 - Behbahani, Mehdi A1 - Borrmann, E. A1 - Elgeti, S. A1 - Nicolai, M. A1 - Behr, M. T1 - Hemodynamic Modeling for Numerical Analysis and Design of Medical Devices Y1 - 2010 N1 - Posterpresentation ; NIC Symposium 2010 ; 24 - 25 February 2010 Jülich, Germany ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Waluga, C. A1 - Stock, S. A1 - Mai, A. A1 - Bergmann, B. A1 - Behr, M. A1 - Tran, L. A1 - Vonderstein, K. A1 - Scheidt, H. A1 - Oedekoven, B. A1 - Mottaghy, K. T1 - Modelling and Numerical Analysis of Platelet Reactions and Surface Thrombus Growth Y1 - 2009 N1 - Posterpresentation ; European Society of Biomaterials (ESB), Lausanne, Switzerland, September 7-10, 2009 ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Mai, A. A1 - Bergmann, B. A1 - Waluga, C. A1 - Behr, M. A1 - Tran, L. A1 - Vonderstein, K. A1 - Mottaghy, K. T1 - Modeling and Numerical Simulation of Blood Damage Y1 - 2010 N1 - Posterpresentation ; Umbrella Symposium "Modelling and Simulation in Medicine, Engineering and Sciences", Forschungszentrum Jülich, January 18-20, 2010 ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Waluga, C. A1 - Arlt, S. A1 - Behr, M. A1 - Mottaghy, K. T1 - Computational Analysis of Platelet Aggregation in a Taylor-Couette System JF - The International Journal of Artificial Organs. 31 (2008), H. 7 Y1 - 2008 SN - 0391-3988 N1 - Posterpresentation ; European Society of Artificial Organs (ESAO), Geneva, Switzerland SP - 643 ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Mai, A. A1 - Waluga, C. A1 - Bergmann, B. A1 - Tran, L. A1 - Vonderstein, K. A1 - Behr, M. A1 - Mottaghy, K. T1 - Numerical Modeling of Flow-Related Thrombus Formation under Physiological and Non-Physiological Flow Conditions JF - Acta Physiologica Y1 - 2010 SN - 1748-1716 N1 - Joint Congress of the Scandinavian and German Physiological Societies, Copenhagen, Denmark, March 27-30, 2010 VL - 198 IS - Supplement 677 SP - 185 ER - TY - JOUR A1 - Spelthahn, Heiko A1 - Kirsanov, Dmitry A1 - Legin, Andrey A1 - Osterrath, Thomas A1 - Schubert, Jürgen A1 - Zander, Willi A1 - Schöning, Michael Josef T1 - Development of a thin-film sensor array for analytical monitoring of heavy metals in aqueous solutions JF - Physica Status Solidi (a) N2 - In industrial processes there is a variety of heavy metals (e.g., copper, zinc, cadmium, and lead) in use for wires, coatings, paints, alloys, batteries, etc. Since the application of these transition metals for industry is inevitable, it is a vital task to develop proper analytical techniques for their monitoring at low activity levels, especially because most of these elements are acutely toxic for biological organisms. The determination of ions in solution by means of a simple and inexpensive sensor array is, therefore, a promising task. In this work, a sensor array with heavy metal-sensitive chalcogenide glass membranes for the simultaneous detection of the four ions Ag⁺, Cu2⁺, Cd2⁺, and Pb2⁺ in solution is realized. The results of the physical characterization by means of microscopy, profilometry, Rutherford backscattering spectroscopy (RBS), and scanning electron microscopy (SEM) as well as the electrochemical characterization by means of potentiometric measurements are presented. Additionally, the possibility to expand the sensor array by polymeric sensor membranes is discussed. Y1 - 2012 SN - 1862-6319 U6 - https://doi.org/10.1002/pssa.201100733 VL - 209 IS - 5 SP - 885 EP - 891 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Spelthahn, Heiko A1 - Schubert, Jürgen A1 - Schöning, Michael Josef T1 - Dünnschichtsensoren für die Schwermetallanalytik JF - GIT : Labor-Fachzeitschrift N2 - Die Detektion von Schadstoffen repräsentiert in der Umweltanalytik eine wichtige Aufgabenstellung. Gerade die Abwasser- bzw. Brauchwasseranalytik sowie die Prozesskontrolle haben einen hohen Stellenwert. Siliziumbasierte Dünnschichtsensoren bieten eine kostengünstige Möglichkeit, „online“-Messungen bzw. Vor-Ort-Messungen zeitnah durchzuführen. In dieser Arbeit wird ein potentiometrisches Sensorarray auf der Basis von Chalkogenidgläsern zur Detektion von Schwermetallen in wässrigen Medien vorgestellt. Y1 - 2012 SN - 0016-3538 VL - 56 IS - 4 SP - 285 EP - 287 PB - Wiley-VCH CY - Weinheim ER - TY - CHAP A1 - Gerhards, Michael A1 - Sander, Volker A1 - Belloum, Adam ED - Zimmermann, Wolf ED - Lee, Yong Woo ED - Demchenko, Yuri T1 - About the flexible Migration of Workflow Tasks to Clouds : Combining on- and off-premise Executions of Applications T2 - CLOUD COMPUTING 2012 : The Third International Conference on Cloud Computing, GRIDs, and Virtualization ; July 22-27, 2012 - Nice, France N2 - An increasing number of applications target their executions on specific hardware like general purpose Graphics Processing Units. Some Cloud Computing providers offer this specific hardware so that organizations can rent such resources. However, outsourcing the whole application to the Cloud causes avoidable costs if only some parts of the application benefit from the specific expensive hardware. A partial execution of applications in the Cloud is a tradeoff between costs and efficiency. This paper addresses the demand for a consistent framework that allows for a mixture of on- and off-premise calculations by migrating only specific parts to a Cloud. It uses the concept of workflows to present how individual workflow tasks can be migrated to the Cloud whereas the remaining tasks are executed on-premise. KW - Workflow Orchestration KW - Workflow KW - Grid Computing KW - Cloud Service Broker KW - Cloud Computing Y1 - 2012 SN - 978-1-61208-216-5 SP - 82 EP - 87 PB - IARIA Journals ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Lanzl, Ines M. T1 - Can vascular function be assessed by the interpretation of retinal vascular diameter changes? JF - Investigative Ophthalmology & Visual Science, IOVS. 52 (2011), H. 1 Y1 - 2011 SN - 0146-0404 SP - 635 EP - 636 PB - ARVO CY - Rockville, Md. ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Mücke, Bruno A1 - Vilser, Walthard A1 - Schilling, Rudolf T1 - Effect of aging on retinal artery blood column diameter measured along the vessel axis / Kotliar, Konstantin E. ; Mücke, Bruno ; Vilser, Walthard ; Schilling, Rudolf ; Lanzl, Ines M. JF - Investigative Ophthalmology & Visual Science, IOVS. 49 (2008), H. 5 Y1 - 2008 SN - 0146-0404 SP - 2094 EP - 2102 PB - - ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Lanzl, Ines M. A1 - Hanssen, Henner A1 - Eberhardt, Karla A1 - Vilser, Walthard A1 - Halle, Martin A1 - Heemann, Uwe A1 - Schmidt-Trucksäss, Arno A1 - Baumann, Marcus T1 - Does increased blood pressure rather than aging influence retinal pulse wave velocity? JF - Investigative Ophthalmology & Visual Science, IOVS N2 - Purpose: It was demonstrated previously that retinal pulse wave velocity (rPWV) as a measure of retinal arterial stiffness is increased in aged anamnestically healthy volunteers compared with young healthy subjects. Using novel methodology of rPWV assessment this finding was confirmed and investigated whether it might relate to the increased blood pressure usually accompanying the aging process, rather than to the aging itself. Methods: A total of 12 young 25.5-year-old (24.0–28.8) [median(1st quartile–3rd quartile)] and 12 senior 68.5-year-old (63.8–71.8) anamnestically healthy volunteers; and 12 senior 63.0-year-old (60.8–65.0) validated healthy volunteers and 12 young 33.0-year-old (29.5–35.0) hypertensive patients were examined. Time-dependent alterations of vessel diameter were assessed by the Dynamic Vessel Analyzer in a retinal artery of each subject. The data were filtered and processed using mathematical signal analysis and rPWVs were calculated. Results: rPWV amounted to 1200 (990-1470) RU (relative units)/s in the hypertensive group and to 1040 (700-2230) RU/s in anamnestically healthy seniors. These differed significantly from rPWVs in young healthy group (410 [280–500] RU/s) and in validated healthy seniors (400 [320–510] RU/s). rPWV associated with age and mean arterial pressure (MAP) in the pooled cohort excluded validated healthy seniors. In a regression model these associations remain when alternately adjusted for MAP and age. When including validated healthy seniors in the pooled cohort only association with MAP remains. Conclusions: Both aging (with not excluded cardiovascular risk factors) and mild hypertension are associated with elevated rPWV. rPWV increases to a similar extent both in young mildly hypertensive subjects and in aged anamnestically healthy persons. Healthy aging is not associated with increased rPWV. Y1 - 2012 U6 - https://doi.org/10.1167/iovs.11-8815 SN - 0146-0404 VL - 53 IS - 4 SP - 2119 EP - 2126 PB - ARVO CY - Rockville, Md. ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Nagel, Edgar A1 - Vilser, Walthard A1 - Seidova, Seid-Fatima A1 - Lanzl, Ines T1 - Microstructural alterations of retinal arterial blood column along the vessel axis in systemic hypertension JF - Investigative Ophthalmology & Visual Science, IOVS N2 - Purpose: Image analysis by the retinal vessel analyzer (RVA) observes retinal vessels in their dynamic state online noninvasively along a chosen vessel segment. It has been found that high-frequency diameter changes in the retinal artery blood column along the vessel increase significantly in anamnestically healthy volunteers with increasing age and in patients with glaucoma during vascular dilation. This study was undertaken to investigate whether longitudinal sections of the retinal artery blood column are altered in systemic hypertension. Methods: Retinal arteries of 15 untreated patients with essential arterial hypertension (age, 50.9 ± 11.9 years) and of 15 age-matched anamnestically healthy volunteers were examined by RVA. After baseline assessment, a monochromatic luminance flicker (530–600 nm; 12.5 Hz; 20 s) was applied to evoke retinal vasodilation. Differences in amplitude and frequency of spatial artery blood column diameter change along segments (longitudinal arterial profiles) of 1 mm in length were measured and analyzed using Fourier transformation. Results: In the control group, average reduced power spectra (ARPS) of longitudinal arterial profiles did not differ when arteries changed from constriction to dilation. In the systemic hypertension group, ARPS during constriction, baseline, and restoration were identical and differed from ARPS during dilation (P < 0.05). Longitudinal arterial profiles in both groups showed significant dissimilitude at baseline and restoration (P < 0.05). Conclusions: The retinal artery blood column demonstrates microstructural alterations in systemic hypertension and is less irregular along the vessel axis during vessel dilation. These microstructural changes may be an indication of alterations in vessel wall rigidity, vascular endothelial function, and smooth muscle cells in this disease, leading to impaired perfusion and regulation. Y1 - 2010 U6 - https://doi.org/10.1167/iovs.09-3649 SN - 0146-0404 VL - 51 IS - 4 SP - 2165 EP - 2172 PB - ARVO CY - Rockville, Md. ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Vilser, W. A1 - Schmidt-Trucksäss, A. A1 - Halle, M. A1 - Lanzl, I. M. T1 - Zeitliche Schwingungen retinaler Gefäßdurchmesser bei Gesunden unterschiedlichen Alters : Kreuz- und Autokorrelation für dynamische Gefäßanalyse JF - Der Ophthalmologe Y1 - 2009 SN - 1433-0423 VL - 106 IS - 7 SP - 609 EP - 618 PB - - ER - TY - JOUR A1 - Lanzl, Ines M. A1 - Seidova, Seid-Fatima A1 - Maier, Mathias A1 - Schmidt-Trucksäss, Arno A1 - Halle, Martin A1 - Kotliar, Konstantin T1 - Dynamic retinal vessel response to flicker in age-related macular degeneration patients before and after vascular endothelial growth factor inhibitor injection JF - Acta Ophthalmologica Y1 - 2011 SN - 1755-3768 VL - 89 IS - 5 SP - 472 EP - 479 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Maier, Mathias A1 - Bauer, Svetlana A1 - Feucht, Nikolaus A1 - Lohmann, Chris A1 - Lanzl, Ines T1 - Intravitreal injection of triamcinolone acetonide and intraocular pressure: author's reply JF - Acta Ophthalmologica Y1 - 2008 SN - 1755-3768 VL - 86 IS - 6 SP - 692 EP - 693 PB - - ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Nagel, Edgar A1 - Vilser, Walthard A1 - Lanzl, Ines M. T1 - Functional in vivo assessment of retinal artery microirregularities in glaucoma / Kotliar, Konstantin E. ; Nagel, Edgar ; Vilser, Walthard ; Lanzl, Ines M. JF - Acta Ophthalmologica. 86 (2008), H. 4 Y1 - 2008 SN - 1755-3768 SP - 424 EP - 433 PB - - ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Maier, Mathias A1 - Bauer, Svetlana A1 - Feucht, Nikolaus T1 - Effect of intravitreal injections and volume changes on intraocular pressure: clinical results and biomechanical model / Kotliar, Konstantin ; Maier, Mathias ; Bauer, Svetlana ; Feucht, Nikolaus ; Lohmann, Chris ; Lanzl, Ines JF - Acta Ophthalmologica Scandinavica. 85 (2007), H. 7 Y1 - 2007 SN - 1755-3768 SP - 777 EP - 781 PB - - ER - TY - JOUR A1 - Nurispahic, A. A1 - Kotliar, Konstantin A1 - Lanzl, I. T1 - Messung der Akkommodation mittels optischer Biometrie JF - Der Ophthalmologe Y1 - 2008 SN - 1433-0423 VL - 105 IS - 4 SP - 369 EP - 375 PB - - ER - TY - JOUR A1 - Lanzl, Ines M. A1 - Seidova, Seid-Fatima A1 - Erben, A. A1 - Thürmel, K. A1 - Kotliar, Konstantin T1 - Diffuse stromale Hornhauttrübungen und Veränderungen der Hände JF - Der Ophthalmologe N2 - Bilaterale stromale Hornhauttrübungen sind für den Augenarzt eine differenzialdiagnostische Herausforderung. Im folgenden Beitrag werden 2 Patieninnen (30 und 36 Jahre) mit unterschiedlich stark ausgeprägter stromaler diffuser Hornhauttrübung vorgestellt. Patientin 1 war kleinwüchsig (114 cm) und Patientin 2 normal groß (172 cm). Beide Patientinnen wiesen veränderte Gelenkstrukturen an Hand und Fußgelenken sowie diffuse stromale Hornhauttrübungen auf. Des Weiteren lagen eine Mitral- und Aorteninsuffizienz (Patientin 1) bzw. eine Aorteninsuffizienz (Patientin 2) vor. Die stromalen diffusen Hornhauttrübungen ließen im Zusammenhang mit den Gelenkveränderungen ein Scheie-Syndrom vermuten. Therapeutisch ist bei Patienten mit Visusminderung eine (lamelläre) Keratoplastik sinnvoll. Y1 - 2010 U6 - https://doi.org/10.1007/s00347-009-2066-2 SN - 1433-0423 VL - 107 IS - 4 SP - 363 EP - 365 PB - Springer CY - Berlin ER - TY - JOUR A1 - Wiescher, A. A1 - Kotliar, Konstantin A1 - Neuhann, T. A1 - Lanzl, Ines M. T1 - Rasch progrediente Visusminderung beider Augen bei einem jungen Patienten JF - Der Ophthalmologe N2 - Ein 34-jähriger männlicher Patient stellte sich zur Abklärung einer seit dem 9. Lebensjahr bestehenden und im letzten Jahr rasch progredienten Visusminderung beider Augen bei uns vor. Er beschrieb eine subjektiv zunehmende, im Spiegel für ihn selbst sichtbare, weißliche Trübung in der Pupille beidseits und eine starke Blendempfindlichkeit. Nebenbefundlich gab er rezidivierende Konjunktivitiden und morgens verklebte Lider an. Eine Allergie auf Gräserpollen und eine Unverträglichkeit auf Alkohol sowie mehrere Lebensmittel seien ebenfalls bekannt. Zusätzlich leidet der Patient an stark ausgeprägtem atopischem Ekzem. Dieses wurde nie systemisch, sondern nur bei Bedarf mit kortisonhaltiger Salbe therapiert. Y1 - 2010 U6 - https://doi.org/10.1007/s00347-007-1586-x SN - 1433-0423 VL - 105 IS - 4 SP - 389 EP - 392 PB - Springer CY - Berlin ER -