TY  - JOUR
A1  - Al-Kaidy, Huschyar
A1  - Kuthan, Kai
A1  - Hering, Thomas
A1  - Tippkötter, Nils
T1  - Aqueous droplets used as enzymatic microreactors and their electromagnetic actuation
JF  - Journal of Visualized Experiments
N2  - For the successful implementation of microfluidic reaction systems, such as PCR and electrophoresis, the movement of small liquid volumes is essential. In conventional lab-on-a-chip-platforms, solvents and samples are passed through defined microfluidic channels with complex flow control installations. The droplet actuation platform presented here is a promising alternative. With it, it is possible to move a liquid drop (microreactor) on a planar surface of a reaction platform (lab-in-a-drop). The actuation of microreactors on the hydrophobic surface of the platform is based on the use of magnetic forces acting on the outer shell of the liquid drops which is made of a thin layer of superhydrophobic magnetite particles. The hydrophobic surface of the platform is needed to avoid any contact between the liquid core and the surface to allow a smooth movement of the microreactor. On the platform, one or more microreactors with volumes of 10 µL can be positioned and moved simultaneously. The platform itself consists of a 3 x 3 matrix of electrical double coils which accommodate either neodymium or iron cores. The magnetic field gradients are automatically controlled. By variation of the magnetic field gradients, the microreactors' magnetic hydrophobic shell can be manipulated automatically to move the microreactor or open the shell reversibly. Reactions of substrates and corresponding enzymes can be initiated by merging the microreactors or bringing them into contact with surface immobilized catalysts.
Y1  - 2016
U6  - http://dx.doi.org/10.3791/54643
SN  - 1940-087X
IS  - Issue 126
ER  - 
TY  - JOUR
A1  - Wulfhorst, Helene
A1  - Duwe, Anna-Maria
A1  - Merseburg, Johannes
A1  - Tippkötter, Nils
T1  - Compositional analysis of pretreated (beech) wood using differential scanning calorimetry and multivariate data analysis
JF  - Tetrahedron
N2  - The composition of plant biomass varies depending on the feedstock and pre-treatment conditions and influences its processing in biorefineries. In order to ensure optimal process conditions, the quantitative proportion of the main polymeric components of the pre-treated biomass has to be determined. Current standard procedures for biomass compositional analysis are complex, the measurements are afflicted with errors and therefore often not comparable. Hence, new powerful analytical methods are urgently required to characterize biomass. In this contribution, Differential Scanning Calorimetry (DSC) was applied in combination with multivariate data analysis (MVA) to detect the cellulose content of the plant biomass pretreated by Liquid Hot Water (LHW) and Organosolv processes under various conditions. Unlike conventional techniques, the developed analytic method enables the accurate quantification of monosaccharide content of the plant biomass without any previous sample preparation. It is easy to handle and avoids errors in sample preparation.
Y1  - 2016
U6  - http://dx.doi.org/10.1016/j.tet.2016.04.029
VL  - 72
IS  - 46
SP  - 7329
EP  - 7334
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Engel, M.
A1  - Thieringer, J.
A1  - Tippkötter, Nils
T1  - Microbial electrosynthesis for sustainable biobutanol production
T2  - New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany
Y1  - 2016
SP  - 77
EP  - 78
PB  - DECHEMA
CY  - Frankfurt am Main
ER  - 
TY  - CHAP
A1  - Hering, T.
A1  - Ulber, Roland
A1  - Tippkötter, Nils
T1  - Development of a screening system for antimicrobial surfaces
T2  - New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany
Y1  - 2016
SP  - 129
PB  - DECHEMA
CY  - Frankfurt am Main
ER  - 
TY  - CHAP
A1  - Roth, J.
A1  - Möhring, S.
A1  - Tippkötter, Nils
T1  - Characterization and evaluation of lignocellulosic biomass 130 hydrolysates for ABE fermentation
T2  - New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany
Y1  - 2016
SP  - 130
PB  - DECHEMA
CY  - Frankfurt am Main
ER  - 
TY  - CHAP
A1  - Möhring, S.
A1  - Wulfhorst, H.
A1  - Roth, J.
A1  - Tippkötter, Nils
T1  - Pretreatment strategies for lignocellulosic biomass
T2  - New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany
Y1  - 2016
SP  - 131
PB  - DECHEMA
CY  - Frankfurt am Main
ER  - 
TY  - CHAP
A1  - Capitain, C.
A1  - Hering, T.
A1  - Tippkötter, Nils
A1  - Ulber, R.
T1  - Enzymatic polymerization of lignin model compounds and solubilized lignin in an aqueous ethanol extract
T2  - New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany
Y1  - 2016
SP  - 151
EP  - 152
PB  - DECHEMA
CY  - Frankfurt am Main
ER  - 
TY  - CHAP
A1  - Wulfhorst, H.
A1  - Duwe, A.
A1  - Möhring, S.
A1  - Jurca, O.
A1  - Tippkötter, Nils
T1  - Analysis of pretreated biomass by differential scanning 132 calorimetry and multivariate data analysis
T2  - New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany
Y1  - 2016
SP  - 132
PB  - DECHEMA
CY  - Frankfurt am Main
ER  - 
TY  - JOUR
A1  - Ferrein, Alexander
A1  - Steinbauer, Gerald
T1  - The Interplay of Aldebaran and RoboCup
JF  - KI - Künstliche Intelligenz
Y1  - 2016
U6  - http://dx.doi.org/10.1007/s13218-016-0440-1
SN  - 1610-1987
VL  - 30
IS  - 3-4
SP  - 325
EP  - 326
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Steinbauer, Gerald
A1  - Ferrein, Alexander
T1  - 20 Years of RoboCup
JF  - KI - Künstliche Intelligenz
Y1  - 2016
U6  - http://dx.doi.org/10.1007/s13218-016-0442-z
SN  - 1610-1987
VL  - 30
IS  - 3-4
SP  - 221
EP  - 224
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Ferrein, Alexander
A1  - Steinbauer, Gerald
T1  - Looking back on 20 Years of RoboCup
JF  - KI - Künstliche Intelligenz
Y1  - 2016
U6  - http://dx.doi.org/10.1007/s13218-016-0443-y
SN  - 1610-1987
VL  - 30
IS  - 3-4
SP  - 321
EP  - 323
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Schiffer, Stefan
A1  - Ferrein, Alexander
T1  - Decision-Theoretic Planning with Fuzzy Notions in GOLOG
JF  - International Journal of Uncertainty, Fuzziness and Knowledge-Based Systems
N2  - In this paper we present an extension of the action language Golog that allows for using fuzzy notions in non-deterministic argument choices and the reward function in decision-theoretic planning. Often, in decision-theoretic planning, it is cumbersome to specify the set of values to pick from in the non-deterministic-choice-of-argument statement. Also, even for domain experts, it is not always easy to specify a reward function. Instead of providing a finite domain for values in the non-deterministic-choice-of-argument statement in Golog, we now allow for stating the argument domain by simply providing a formula over linguistic terms and fuzzy uents. In Golog’s forward-search DT planning algorithm, these formulas are evaluated in order to find the agent’s optimal policy. We illustrate this in the Diner Domain where the agent needs to calculate the optimal serving order.
Y1  - 2016
U6  - http://dx.doi.org/10.1142/S0218488516400134
SN  - 1793-6411
VL  - 24
IS  - Issue Suppl. 2
SP  - 123
EP  - 143
PB  - World Scientific
CY  - Singapur
ER  - 
TY  - CHAP
A1  - Barnat, Miriam
A1  - Bosse, Elke
T1  - The challenge of creating meta-inferences: Combining data representing institutional and individual perspectives on first-year support in higher education
T2  - 9th Conference on Social Science Methodology of the International Sociological Association, Leicester, UK
Y1  - 2016
N1  - RC33 Conference 2016
SP  - 1
EP  - 20
ER  - 
TY  - JOUR
A1  - Paulßen, Elisabeth
A1  - Lengkeek, Nigel A.
A1  - Le, Van So
A1  - Pellegrini, Paul A.
A1  - Greguric, Ivan
A1  - Weiner, Ron
T1  - The role of additives in moderating the influence of Fe(III) and Cu(II) on the radiochemical yield of [⁶⁸Ga(DOTATATE)]
JF  - Applied Radiation and Isotopes
N2  - [⁶⁸Ga(DOTATATE)] has demonstrated its clinical usefulness. Both Fe³⁺ and Cu²⁺, potential contaminants in Gallium-68 generator eluent, substantially reduce the radiochemical (RC) yield of [⁶⁸Ga(DOTATATE)] if the metal/ligand ratio of 1:1 is exceeded. A variety of compounds were examined for their potential ability to reduce this effect. Most had no effect on RC yield. However, addition of phosphate diminished the influence of Fe³⁺ by likely forming an insoluble iron salt. Addition of ascorbic acid reduced Cu²⁺ and Fe³⁺ to Cu⁺ and Fe²⁺ respectively, both of which have limited impact on RC yields. At low ligand amounts (5 nmol DOTATATE), the addition of 30 nmol phosphate (0.19 mM) increased the tolerance of Fe3⁺ from 4 nmol to 10 nmol (0.06 mM), while the addition of ascorbic acid allowed high RC yields (>95%) in the presence of 40 nmol Fe³⁺ (0.25 mM) and 100 nmol Cu²⁺ (0.63 mM). The effect of ascorbic acid was highly pH-dependant, and gave optimal results at pH 3.
Y1  - 2016
U6  - http://dx.doi.org/10.1016/j.apradiso.2015.09.008
SN  - 1872-9800
VL  - 107
SP  - 13
EP  - 16
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Infantino, Angelo
A1  - Paulßen, Elisabeth
A1  - Mostacci, Domiziano
A1  - Schaffer, Paul
A1  - Trinczek, Michael
A1  - Hoehr, Cornelia
T1  - Assessment of the production of medical isotopes using the Monte Carlo code FLUKA: Simulations against experimental measurements
JF  - Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
N2  - The Monte Carlo code FLUKA is used to simulate the production of a number of positron emitting radionuclides, ¹⁸F, ¹³N, ⁹⁴Tc, ⁴⁴Sc, ⁶⁸Ga, ⁸⁶Y, ⁸⁹Zr, ⁵²Mn, ⁶¹Cu and ⁵⁵Co, on a small medical cyclotron with a proton beam energy of 13 MeV. Experimental data collected at the TR13 cyclotron at TRIUMF agree within a factor of 0.6 ± 0.4 with the directly simulated data, except for the production of ⁵⁵Co, where the simulation underestimates the experiment by a factor of 3.4 ± 0.4. The experimental data also agree within a factor of 0.8 ± 0.6 with the convolution of simulated proton fluence and cross sections from literature. Overall, this confirms the applicability of FLUKA to simulate radionuclide production at 13 MeV proton beam energy.
Y1  - 2016
U6  - http://dx.doi.org/10.1016/j.nimb.2015.10.067
SN  - 1872-9584
VL  - 366
SP  - 117
EP  - 123
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Kleine, Harald
A1  - Kallweit, Stephan
A1  - Michaux, Frank
A1  - Havermann, Marc
A1  - Olivier, Herbert
T1  - PIV Measurement of Shock Wave Diffraction
T2  - 18th International Symposium on Applications of Laser Techniques to Fluid Mechanics, 2016, Lissabon
Y1  - 2016
SP  - 1
EP  - 14
ER  - 
TY  - CHAP
A1  - Schleupen, Josef
A1  - Engemann, Heiko
A1  - Bagheri, Mohsen
A1  - Kallweit, Stephan
T1  - The potential of SMART climbing robot combined with a weatherproof cabin for rotor blade maintenance
T2  - 17th European Conference on Composite Materials – ECCM, Munich, Germany
Y1  - 2016
N1  - ECCM 17
SP  - 1
EP  - 8
ER  - 
TY  - CHAP
A1  - Wilke, Thomas
ED  - Merlotti, Andrea
T1  - Planning Process of the Di Castellamonte’s Chapel of the Holy Shroud
T2  - Carlo e Amedeo di Castellamonte : 1571-1683, ingegneri e architetti per i duchi di Savoia
Y1  - 2016
SN  - 978-88-98229-57-4
N1  - Architettura e potere ; 4
SP  - 141
EP  - 152
PB  - Campisano editore
CY  - Rom
ER  - 
TY  - CHAP
A1  - Stephan, Achim
A1  - Heuermann, Holger
A1  - Prantner, Michael
T1  - Cutting human tissue with novel atmospheric-pressure microwave plasma jet
T2  - 46th European Microwave Conference (EuMC)
Y1  - 2016
SN  - 978-2-87487-043-9
U6  - http://dx.doi.org/10.1109/EuMC.2016.7824490
SP  - 902
EP  - 905
PB  - IEEE
ER  - 
TY  - JOUR
A1  - Ngamga, Eulalie Joelle
A1  - Bialonski, Stephan
A1  - Marwan, Norbert
A1  - Kurths, Jürgen
A1  - Geier, Christian
A1  - Lehnertz, Klaus
T1  - Evaluation of selected recurrence measures in discriminating pre-ictal and inter-ictal periods from epileptic EEG data
JF  - Physics Letters A
N2  - We investigate the suitability of selected measures of complexity based on recurrence quantification analysis and recurrence networks for an identification of pre-seizure states in multi-day, multi-channel, invasive electroencephalographic recordings from five epilepsy patients. We employ several statistical techniques to avoid spurious findings due to various influencing factors and due to multiple comparisons and observe precursory structures in three patients. Our findings indicate a high congruence among measures in identifying seizure precursors and emphasize the current notion of seizure generation in large-scale epileptic networks. A final judgment of the suitability for field studies, however, requires evaluation on a larger database.
Y1  - 2016
U6  - http://dx.doi.org/10.1016/j.physleta.2016.02.024
SN  - 0375-9601
VL  - 380
IS  - 16
SP  - 1419
EP  - 1425
PB  - Elsevier
CY  - Amsterdam
ER  -