TY  - JOUR
A1  - Grieger, Niklas
A1  - Schwabedal, Justus T. C.
A1  - Wendel, Stefanie
A1  - Ritze, Yvonne
A1  - Bialonski, Stephan
T1  - Automated scoring of pre-REM sleep in mice with deep learning
JF  - Scientific Reports
N2  - Reliable automation of the labor-intensive manual task of scoring animal sleep can facilitate the analysis of long-term sleep studies. In recent years, deep-learning-based systems, which learn optimal features from the data, increased scoring accuracies for the classical sleep stages of Wake, REM, and Non-REM. Meanwhile, it has been recognized that the statistics of transitional stages such as pre-REM, found between Non-REM and REM, may hold additional insight into the physiology of sleep and are now under vivid investigation. We propose a classification system based on a simple neural network architecture that scores the classical stages as well as pre-REM sleep in mice. When restricted to the classical stages, the optimized network showed state-of-the-art classification performance with an out-of-sample F1 score of 0.95 in male C57BL/6J mice. When unrestricted, the network showed lower F1 scores on pre-REM (0.5) compared to the classical stages. The result is comparable to previous attempts to score transitional stages in other species such as transition sleep in rats or N1 sleep in humans. Nevertheless, we observed that the sequence of predictions including pre-REM typically transitioned from Non-REM to REM reflecting sleep dynamics observed by human scorers. Our findings provide further evidence for the difficulty of scoring transitional sleep stages, likely because such stages of sleep are under-represented in typical data sets or show large inter-scorer variability. We further provide our source code and an online platform to run predictions with our trained network.
Y1  - 2021
U6  - https://doi.org/10.1038/s41598-021-91286-0
SN  - 2045-2322
N1  - Corresponding author: Stephan Bialonski
VL  - 11
IS  - Art. 12245
PB  - Springer Nature
CY  - London
ER  - 
TY  - JOUR
A1  - Heuermann, Holger
A1  - Schiek, Burkhard
T1  - Line Network Network (LNN): an alternative in-fixture calibration procedure
JF  - IEEE transactions on microwave theory and techniques : MTT ; a publication of the IEEE Microwave Theory and Techniques Society. 45 (1997), H. 3
Y1  - 1997
SN  - 0018-9480
SP  - 408
EP  - 413
ER  - 
TY  - JOUR
A1  - Heuermann, Holger
A1  - Peters, N.
A1  - Schmitz, T.
A1  - Sadeghfam, Arash
T1  - Concept of Balanced Antennas with Load-Invariant Base Impedance Using a Two Element LC-Coupler. Peters, N., Schmitz, Th., Sadeghfam, A., Heuermann, H.
JF  - Proceedings of the European microwave association : journal of the European microwave association
Y1  - 2005
SP  - 117
EP  - 122
PB  - PLUS
CY  - Pisa
ER  - 
TY  - CHAP
A1  - Alhwarin, Faraj
A1  - Ferrein, Alexander
A1  - Scholl, Ingrid
T1  - CRVM: Circular Random Variable-based Matcher - A Novel Hashing Method for Fast NN Search in High-dimensional Spaces
T2  - Proceedings of the 7th International Conference on Pattern Recognition Applications and Methods, ICPRAM 2018
Y1  - 2018
SN  - 978-989-758-276-9
U6  - https://doi.org/10.5220/0006692802140221
SP  - 214
EP  - 221
ER  - 
TY  - CHAP
A1  - Schleupen, Josef
A1  - Engemann, Heiko
A1  - Bagheri, Mohsen
A1  - Kallweit, Stephan
A1  - Dahmann, Peter
T1  - Developing a climbing maintenance robot for tower and rotor blade service of wind turbines
T2  - Advances in Robot Design and Intelligent Control : Proceedings of the 25th Conference on Robotics in Alpe-Adria-Danube Region (RAAD16)
Y1  - 2017
SN  - 978-3-319-49058-8
U6  - https://doi.org/10.1007/978-3-319-49058-8_34
N1  - Advances in Robot Design and Intelligent Control ; Vol. 540
SP  - 310
EP  - 319
PB  - Springer
CY  - Cham
ER  - 
TY  - JOUR
A1  - Foltz, Christian
A1  - Schneider, Nicole
A1  - Wolf, Martin R.
A1  - Kausch, Bernhard
A1  - Schlick, Christopher
A1  - Luczak, Holger
ED  - Nagl, Manfred
T1  - Usability engineering
JF  - Collaborative and distributed chemical engineering : from understanding to substantial design process support; results of the IMPROVE Project. - (Lecture notes in computer science ; 4970)
Y1  - 2008
SN  - 978-3-540-70552-9
U6  - https://doi.org/10.1007/978-3-540-70552-9_21
SP  - 527
EP  - 554
PB  - Springer
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Alhwarin, Faraj
A1  - Schiffer, Stefan
A1  - Ferrein, Alexander
A1  - Scholl, Ingrid
T1  - Optimized KinectFusion Algorithm for 3D Scanning Applications
T2  - Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 2: BIOIMAGING
Y1  - 2018
SN  - 978-989-758-278-3
U6  - https://doi.org/10.5220/0006594700500057
SP  - 50
EP  - 57
ER  - 
TY  - CHAP
A1  - Pham, Phu Tinh
A1  - Nguyen, Thanh Ngoc
A1  - Staat, Manfred
T1  - FEM based shakedown analysis of hardening structures
T2  - Proceedings International Conference on Advances in Computational Mechanics (ACOME)
Y1  - 2012
N1  - International Conference on Advances in Computational Mechanics (ACOME), August 14-16, 2012, Ho Chi Minh City, Vietnam
SP  - 870
EP  - 882
ER  - 
TY  - JOUR
A1  - Ferrein, Alexander
A1  - Beck, Daniel
A1  - Lakemeyer, Gerhard
T1  - A Simulation Environment for Middle-Size Robots with Multi-level Abstraction / Beck, Daniel ; Ferrein, Alexander ; Lakemeyer, Gerhard
JF  - RoboCup 2007: Robot Soccer World Cup XI
Y1  - 2007
SN  - 978-3-540-68846-4
N1  - Lecture Notes in Computer Science ; 5001
SP  - 136
EP  - 147
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Fabo, Sabine
T1  - Learning from Brachelen
JF  - Freistil (Boxhorn ; 8)
Y1  - 2002
SP  - 2,1
EP  - 2,31
PB  - FH Aachen, Fachbereich Gestaltung
CY  - Aachen
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Nanomaterial-Modified Capacitive Field-Effect Biosensors
T2  - Springer Series on Chemical Sensors and Biosensors (Methods and Applications)
N2  - The coupling of charged molecules, nanoparticles, and more generally, inorganic/organic nanohybrids with semiconductor field-effect devices based on an electrolyte–insulator–semiconductor (EIS) system represents a very promising strategy for the active tuning of electrochemical properties of these devices and, thus, opening new opportunities for label-free biosensing by the intrinsic charge of molecules. The simplest field-effect sensor is a capacitive EIS sensor, which represents a (bio-)chemically sensitive capacitor. In this chapter, selected examples of recent developments in the field of label-free biosensing using nanomaterial-modified capacitive EIS sensors are summarized. In the first part, we present applications of EIS sensors modified with negatively charged gold nanoparticles for the label-free electrostatic detection of positively charged small proteins and macromolecules, for monitoring the layer-by-layer formation of oppositely charged polyelectrolyte (PE) multilayers as well as for the development of an enzyme-based biomolecular logic gate. In the second part, examples of a label-free detection by means of EIS sensors modified with a positively charged weak PE layer are demonstrated. These include electrical detection of on-chip and in-solution hybridized DNA (deoxyribonucleic acid) as well as an EIS sensor with pH-responsive weak PE/enzyme multilayers for enhanced field-effect biosensing.
KW  - Biomolecular logic gate
KW  - DNA
KW  - Enzyme biosensor
KW  - Field-effect sensor
KW  - Gold nanoparticle
Y1  - 2017
U6  - https://doi.org/10.1007/5346_2017_2
SP  - 1
EP  - 25
PB  - Springer
CY  - Berlin, Heidelberg
ER  - 
TY  - JOUR
A1  - Heuermann, Holger
A1  - Sadeghfam, Arash
T1  - On the design of multimode integrated circuits in multilayered processes / Sadeghfam, A. ; Heuermann, H.
JF  - European Microwave Conference, 2007, 9-12 Oct. 2007
Y1  - 2007
SN  - 978-2-87487-001-9
N1  - EuMC 2007 ; European Microwave Conference ; (37 : ; 2007.10.09-12 : ; Munich)
SP  - 516
EP  - 519
ER  - 
TY  - CHAP
A1  - Ferrein, Alexander
T1  - Robots: challenges, chances and risks for solving 21st century problems
T2  - President’s Invitation Lecture / South African Institute of Electrical Engineers : May 21 & 22, 2015, University of Johannesburg
Y1  - 2015
SP  - 1
EP  - 45
ER  - 
TY  - JOUR
A1  - Hennecke, Klaus
A1  - Schwarzbözl, Peter
A1  - Hoffschmidt, Bernhard
A1  - Göttsche, Joachim
A1  - Koll, G.
A1  - Beuter, M.
A1  - Hartz, T.
T1  - The solar power tower Jülich – a solar thermal power plant for test and demonstration of air receiver
JF  - Solar energy and human settlement : Elektronische Ressource : proceedings of ISES world congress 2007 ; (Vol. I - Vol. V) / [ISES Solar World Congress. ISES, International Solar Energy Society]. D. Yogi Goswami ; Yuwen Zhao
Y1  - 2007
SN  - 978-7-302-16146-2
N1  - Solar World Congress <2007, Beijing> ; International Solar Energy Society
SP  - 1749
EP  - 1753
PB  - Tsinghua Univ. Press
CY  - Beijing
ER  - 
TY  - JOUR
A1  - Stulpe, Werner
A1  - Scholz, Erhard
T1  - Hilbert Space / Scholz, Erhard ; Stulpe, Werner
JF  - Compendium of Quantum Physics : concepts, experiments, history and philosophy / Daniel Greenberger ... ed.
Y1  - 2009
SN  - 978-3-540-70622-9
SP  - 291
EP  - 295
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Stulpe, Werner
T1  - Density Operator
JF  - Compendium of Quantum Physics : concepts, experiments, history and philosophy / Daniel Greenberger ... ed.
Y1  - 2009
SN  - 978-3-540-70622-9
SP  - 166
EP  - 169
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Finger, Felix
A1  - Götten, Falk
A1  - Braun, Carsten
A1  - Bil, Cees
T1  - Mass, primary energy, and cost: the impact of optimization objectives on the initial sizing of hybrid-electric general aviation aircraft
JF  - CEAS Aeronautical Journal
N2  - For short take-off and landing (STOL) aircraft, a parallel hybrid-electric propulsion system potentially offers superior performance compared to a conventional propulsion system, because the short-take-off power requirement is much higher than the cruise power requirement. This power-matching problem can be solved with a balanced hybrid propulsion system. However, there is a trade-off between wing loading, power loading, the level of hybridization, as well as range and take-off distance. An optimization method can vary design variables in such a way that a minimum of a particular objective is attained. In this paper, a comparison between the optimization results for minimum mass, minimum consumed primary energy, and minimum cost is conducted. A new initial sizing algorithm for general aviation aircraft with hybrid-electric propulsion systems is applied. This initial sizing methodology covers point performance, mission performance analysis, the weight estimation process, and cost estimation. The methodology is applied to the design of a STOL general aviation aircraft, intended for on-demand air mobility operations. The aircraft is sized to carry eight passengers over a distance of 500 km, while able to take off and land from short airstrips. Results indicate that parallel hybrid-electric propulsion systems must be considered for future STOL aircraft.
Y1  - 2020
U6  - https://doi.org/10.1007/s13272-020-00449-8
SN  - 1869-5590
N1  - Corresponding author: Felix Finger
VL  - 2020
IS  - 11
SP  - 713
EP  - 730
PB  - Springer
CY  - Heidelberg
ER  - 
TY  - JOUR
A1  - Tran, Ngoc Trinh
A1  - Staat, Manfred
T1  - Direct plastic structural design under lognormally distributed strength by chance constrained programming
JF  - Optimization and Engineering
N2  - We propose the so-called chance constrained programming model of stochastic programming theory to analyze limit and shakedown loads of structures under random strength with a lognormal distribution. A dual chance constrained programming algorithm is developed to calculate simultaneously both the upper and lower bounds of the plastic collapse limit and the shakedown limit. The edge-based smoothed finite element method (ES-FEM) is used with three-node linear triangular elements.
Y1  - 2020
U6  - https://doi.org/10.1007/s11081-019-09437-2
SN  - 1573-2924
VL  - 21
IS  - 1
SP  - 131
EP  - 157
PB  - Springer Nature
CY  - Cham
ER  - 
TY  - JOUR
A1  - Gun, Jenny
A1  - Gutkin, Vitaly
A1  - Lev, Ovadia
A1  - Boyen, Hans-Gerd
A1  - Saitner, Marc
A1  - Wagner, Patrick
A1  - Olieslaeger, Marc D´
A1  - Abouzar, Maryam H.
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Tracing gold nanoparticle charge by electrolyte-insulator-semiconductor devices
JF  - Journal of Physical Chemistry C. 115 (2011), H. 11
Y1  - 2011
SN  - 1932-7455
SP  - 4439
EP  - 4445
PB  - American Cemical Society
CY  - Washington, DC
ER  - 
TY  - JOUR
A1  - Gun, Jenny
A1  - Rizkov, Dan
A1  - Lev, Ovadia
A1  - Abouzar, Maryam H.
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Oxygen plasma-treated gold nanoparticle-based field-effect devices as transducer structures for bio-chemical sensing
JF  - Microchimica Acta. 164 (2008), H. 3-4
Y1  - 2008
SN  - 1436-5073
SP  - 395
EP  - 404
ER  -