TY - CHAP A1 - Koch, Claudia A1 - Poghossian, Arshak A1 - Wege, Christina A1 - Schöning, Michael Josef ED - Wege, Christina T1 - TMV-Based Adapter Templates for Enhanced Enzyme Loading in Biosensor Applications T2 - Virus-Derived Nanoparticles for Advanced Technologies N2 - Nanotubular tobacco mosaic virus (TMV) particles and RNA-free lower-order coat protein (CP) aggregates have been employed as enzyme carriers in different diagnostic layouts and compared for their influence on biosensor performance. In the following, we describe a label-free electrochemical biosensor for improved glucose detection by use of TMV adapters and the enzyme glucose oxidase (GOD). A specific and efficient immobilization of streptavidin-conjugated GOD ([SA]-GOD) complexes on biotinylated TMV nanotubes or CP aggregates was achieved via bioaffinity binding. Glucose sensors with adsorptively immobilized [SA]-GOD, and with [SA]-GOD cross-linked with glutardialdehyde, respectively, were tested in parallel on the same sensor chip. Comparison of these sensors revealed that TMV adapters enhanced the amperometric glucose detection remarkably, conveying highest sensitivity, an extended linear detection range and fastest response times. These results underline a great potential of an integration of virus/biomolecule hybrids with electronic transducers for applications in biosensorics and biochips. Here, we describe the fabrication and use of amperometric sensor chips combining an array of circular Pt electrodes, their loading with GOD-modified TMV nanotubes (and other GOD immobilization methods), and the subsequent investigations of the sensor performance. KW - Tobacco mosaic virus (TMV) KW - Coat protein KW - Enzyme nanocarrier KW - Glucose biosensor KW - Glucose oxidase Y1 - 2018 SN - 978-1-4939-7808-3 U6 - https://doi.org/10.1007/978-1-4939-7808-3 N1 - Methods in Molecular Biology, vol 1776 SP - 553 EP - 568 PB - Humana Press CY - New York, NY ER - TY - JOUR A1 - Siqueira, José R. Jr. A1 - Abouzar, Maryam H. A1 - Poghossian, Arshak A1 - Zucolotto, Valtencir A1 - Oliveira, Osvaldo N. Jr. A1 - Schöning, Michael Josef T1 - Penicillin biosensor based on a capacitive field-effect structure functionalized with a dendrimer/carbon nanotube multilayer JF - Biosensors and Bioelectronics. 25 (2009), H. 2 Y1 - 2009 SN - 0956-5663 SP - 497 EP - 501 ER - TY - CHAP A1 - Butenweg, Christoph A1 - Meyer, Udo A1 - Fehling, Ekkehard T1 - INSYSME: first activities of the German partners T2 - 9th International Masonry Conference 2014 in Guimaraes, Portugal, 2014 Y1 - 2014 ER - TY - JOUR A1 - Fabo, Sabine T1 - Arts and media : towards an universal understanding JF - Leonardo Y1 - 1993 SN - 0024-094X VL - 26(1993) IS - 4 SP - 316 EP - 319 ER - TY - JOUR A1 - Gamella, Maria A1 - Zakharchenko, Andrey A1 - Guz, Nataliia A1 - Masi, Madeline A1 - Minko, Sergiy A1 - Kolpashchikov, Dmitry M. A1 - Iken, Heiko A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Katz, Evgeny T1 - DNA computing system activated by electrochemically triggered DNA realease from a polymer-brush-modified electrode array JF - Electroanalysis N2 - An array of four independently wired indium tin oxide (ITO) electrodes was used for electrochemically stimulated DNA release and activation of DNA-based Identity, AND and XOR logic gates. Single-stranded DNA molecules were loaded on the mixed poly(N,N-dimethylaminoethyl methacrylate) (PDMAEMA)/poly(methacrylic acid) (PMAA) brush covalently attached to the ITO electrodes. The DNA deposition was performed at pH 5.0 when the polymer brush is positively charged due to protonation of tertiary amino groups in PDMAEMA, thus resulting in electrostatic attraction of the negatively charged DNA. By applying electrolysis at −1.0 V(vs. Ag/AgCl reference) electrochemical oxygen reduction resulted in the consumption of hydrogen ions and local pH increase near the electrode surface. The process resulted in recharging the polymer brush to the negative state due to dissociation of carboxylic groups of PMAA, thus repulsing the negatively charged DNA and releasing it from the electrode surface. The DNA release was performed in various combinations from different electrodes in the array assembly. The released DNA operated as input signals for activation of the Boolean logic gates. The developed system represents a step forward in DNA computing, combining for the first time DNA chemical processes with electronic input signals. Y1 - 2017 U6 - https://doi.org/10.1002/elan.201600389 SN - 1521-4109 VL - 29 IS - 2 SP - 398 EP - 408 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Abouzar, Maryam H. A1 - Poghossian, Arshak A1 - Razavi, Arash A1 - Besmehn, Astrid A1 - Bijnens, Nathalie A1 - Williams, Oliver A. A1 - Haenen, Ken A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Penicillin detection with nanocrystalline-diamond field-effect sensor JF - physica status solidi (a). 205 (2008), H. 9 Y1 - 2008 SN - 1862-6319 N1 - Special Issue: Hasselt Diamond Workshop 2008 - SBDD XIII SP - 2141 EP - 2145 ER - TY - CHAP A1 - Priede, Gareth A1 - Ferrein, Alexander T1 - Towards passive walking for the fully-actuated biped robot Nao T2 - Emerging trends in computing, informatics, systems sciences, and engineering. (Lecture notes in electrical engineering : vol. 151) N2 - Many biped robots deploy a form of gait that follows the zero moment point (ZMP) approach, that is, the robot is in a stable position at any point in time. This requires the robot to be fully actuated. While very stable, the draw-backs of this approach are a fairly slow gait and high energy consumption. An alternative approach is the so-called passive-dynamic walking, where the gait makes use of the inertia and dynamic stability of the robot. In this paper we describe our ongoing work of combining the principles of passive-dynamic walking on the fully-actuated biped robot Nao, which is also deployed for robotic soccer applications. We present a simple controller that allows the robot to stably rock sidewards, showing a closed limit-cycle. We discuss first results of superimposing a forward motion on the sidewards motion. Based on this we expect to endow the Nao with a fast, robust, and stable passive-dynamic walk on the fully-actuated Nao in the future. Y1 - 2013 SN - 978-1-4614-3557-0 ; 978-1-4614-3558-7 U6 - https://doi.org/10.1007/978-1-4614-3558-7_18 SP - 225 EP - 236 PB - Springer CY - New York, NY ER - TY - JOUR A1 - Gossmann, Matthias A1 - Thomas, Ulrich A1 - Horváth, András A1 - Dragicevic, Elena A1 - Stoelzle-Feix, Sonja A1 - Jung, Alexander A1 - Raman, Aravind Hariharan A1 - Staat, Manfred A1 - Linder, Peter T1 - A higher-throughput approach to investigate cardiac contractility in vitro under physiological mechanical conditions JF - Journal of Pharmacological and Toxicological Methods Y1 - 2020 U6 - https://doi.org/10.1016/j.vascn.2020.106843 VL - 105 IS - Article 106843 PB - Elsevier CY - New York, NY ER - TY - CHAP A1 - Hoffschmidt, Bernhard A1 - Alexopoulos, Spiros A1 - Rau, Christoph A1 - Sattler, Johannes Christoph A1 - Anthrakidis, Anette A1 - Teixeira Boura, Cristiano José A1 - O'Connor, P. A1 - Hilger, Patrick T1 - Concentrating solar power T2 - Comprehensive renewable energy / ed. Ali Sayigh. Vol. 3: Solar thermal systems: components and applications Y1 - 2012 SN - 978-0-08-087872-0 U6 - https://doi.org/10.1016/B978-0-08-087872-0.00319-X VL - 3 SP - 595 EP - 636 PB - Elsevier CY - Amsterdam ER - TY - THES A1 - Jung, Alexander T1 - Electromechanical modelling and simulation of hiPSC-derived cardiac cell cultures Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?https://nbn-resolving.org/urn:nbn:de:hbz:464-20210624-134942-7 SN - 978-3-9821811-1-0 N1 - Dissertation, Universität Duisburg-Essen, 2021 PB - Universität Duisburg-Essen ER - TY - JOUR A1 - Ferrein, Alexander A1 - Schiffer, Stefan A1 - Lakemeyer, Gerhard T1 - Embedding fuzzy controllers in golog / Ferrein, Alexander ; Schiffer, Stefan ; Lakemeyer, Gerhard JF - IEEE International Conference on Fuzzy Systems, 2009. FUZZ-IEEE 2009 Y1 - 2009 SN - 978-1-4244-3596-8 SP - 894 EP - 899 PB - IEEE CY - New York ER - TY - JOUR A1 - Abouzar, Maryam H. A1 - Ingebrandt, S. A1 - Poghossian, Arshak A1 - Zhang, Y. A1 - Moritz, W. A1 - Schöning, Michael Josef T1 - Field-effect nanoplate capacitive pH sensor based on SOI structure JF - Semiconductor micro- and nanoelectronics : Proceedings of the Seventh International Conference , Tsakhcadzor, Armenia July 3-5 2009 Y1 - 2009 SP - 55 EP - 58 ER - TY - JOUR A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - "High-order” hybrid FET module for (bio)chemical and physical sensing JF - Integrated analytical systems / ed. by Salvador Alegret Y1 - 2003 SN - 0-444-51037-0 SP - 587 EP - 623 PB - Elsevier CY - Amsterdam [u.a.] ER - TY - JOUR A1 - Wu, Chunsheng A1 - Bronder, Thomas A1 - Poghossian, Arshak A1 - Werner, Frederik A1 - Schöning, Michael Josef T1 - Label-free detection of DNA using light-addressable potentiometric sensor modified with a positively charged polyelectrolyte layer JF - Nanoscale N2 - A multi-spot (16 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al–p-Si–SiO2 structure modified with a weak polyelectrolyte layer of PAH (poly(allylamine hydrochloride)) was applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. To achieve a preferentially flat orientation of DNA strands and thus, to reduce the distance between the DNA charge and MLAPS surface, the negatively charged probe single-stranded DNAs (ssDNA) were electrostatically adsorbed onto the positively charged PAH layer using a simple layer-by-layer (LbL) technique. In this way, more DNA charge can be positioned within the Debye length, yielding a higher sensor signal. The surface potential changes in each spot induced due to the surface modification steps (PAH adsorption, probe ssDNA immobilization, hybridization with complementary target DNA (cDNA), non-specific adsorption of mismatched ssDNA) were determined from the shifts of photocurrent–voltage curves along the voltage axis. A high sensor signal of 83 mV was registered after immobilization of probe ssDNA onto the PAH layer. The hybridization signal increases from 5 mV to 32 mV with increasing the concentration of cDNA from 0.1 nM to 5 μM. In contrast, a small signal of 5 mV was recorded in the case of non-specific adsorption of fully mismatched ssDNA (5 μM). The obtained results demonstrate the potential of the MLAPS in combination with the simple and rapid LbL immobilization technique as a promising platform for the future development of multi-spot light-addressable label-free DNA chips with direct electrical readout. Y1 - 2015 U6 - https://doi.org/10.1039/C4NR07225A VL - 14 IS - 7 SP - 6143 EP - 6150 PB - Royal Society of Chemistry (RSC) CY - Cambridge ER - TY - CHAP A1 - Rahier, Michael A1 - Ritz, Thomas A1 - Wallenborn, Ramona T1 - Information and communication technology for integrated mobility concepts such as E-carsharing T2 - E-Mobility in Europe : trends and good practice N2 - During the past decade attitude towards sharing things has changed extremely. Not just personal data is shared (e.g. in social networks) but also mobility. Together with the increased ecological awareness of the recent years, new mobility concepts have evolved. E-carsharing has become a symbol for these changes of attitude. The management of a shared car fleet, the energy management of electric mobility and the management of various carsharing users with individual likes and dislikes are just some of the major challenges of e-carsharing. Weaving it into integrated mobility concepts, this raises complexity even further. These challenges can only be overcome by an appropriate amount of well-shaped information available at the right place and time. In order to gather, process and share the required information, fleet cars have to be equipped with modern information and communication technology (ICT) and become so-called fully connected cars. Ensuring the usability of these ICT systems is another challenge that is often neglected, even though it is usability that makes carsharing comfortable, attractive and supports users’ new attitudes. By means of an integrated and consistent concept for human-machine interaction (HMI), the usability of such systems can be raised tremendously. KW - Information and communication technology KW - Fully connected car KW - E-carsharing KW - Mobility management KW - Integrated mobility Y1 - 2015 SN - 978-3-319-13193-1 U6 - https://doi.org/10.1007/978-3-319-13194-8_17 SP - 311 EP - 326 PB - Springer CY - Cham [u.a.] ER - TY - JOUR A1 - Becker, Jörg A1 - Delfmann, Patrick A1 - Eggert, Mathias A1 - Schwittay, Sebastian T1 - Generalizability and Applicability of Model-Based Business Process Compliance-Checking Approaches — A State-of-the-Art Analysis and Research Roadmap JF - Business Research : BuR N2 - With a steady increase of regulatory requirements for business processes, automation support of compliance management is a field garnering increasing attention in Information Systems research. Several approaches have been developed to support compliance checking of process models. One major challenge for such approaches is their ability to handle different modeling techniques and compliance rules in order to enable widespread adoption and application. Applying a structured literature search strategy, we reflect and discuss compliance-checking approaches in order to provide an insight into their generalizability and evaluation. The results imply that current approaches mainly focus on special modeling techniques and/or a restricted set of types of compliance rules. Most approaches abstain from real-world evaluation which raises the question of their practical applicability. Referring to the search results, we propose a roadmap for further research in model-based business process compliance checking. Y1 - 2012 U6 - https://doi.org/10.1007/BF03342739 SN - 1866-8658 VL - 5 IS - 2 SP - 221 EP - 247 PB - Springer CY - Heidelberg ER - TY - CHAP A1 - Neumann, Tobias A1 - Dülberg, Enno A1 - Schiffer, Stefan A1 - Ferrein, Alexander T1 - A rotating platform for swift acquisition of dense 3D point clouds T2 - Intelligent Robotics and Applications: 9th International Conference, ICIRA 2016, Tokyo, Japan, August 22-24, 2016, Proceedings, Part I Y1 - 2016 SN - 978-3-319-43505-3 (Print) SN - 978-3-319-43506-0 (Online) U6 - https://doi.org/10.1007/978-3-319-43506-0_22 N1 - Series: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) VL - 9834 SP - 257 EP - 268 PB - Springer ER - TY - JOUR A1 - Beging, Stefan A1 - Mlynek, Daniela A1 - Hataihimakul, Sudkanung A1 - Poghossian, Arshak A1 - Baldsiefen, Gerhard A1 - Busch, Heinz A1 - Laube, Norbert A1 - Kleinen, Lisa A1 - Schöning, Michael Josef T1 - Field-effect calcium sensor for the determination of the risk of urinary stone formation JF - Sensors and Actuators B: Chemical. 144 (2010), H. 2 Y1 - 2010 N1 - 22nd International Conference on Eurosensors - Dresden, Germany, 7-10 September 2008 ; Eurosensors ; (22, 2008, Dresden) SP - 374 EP - 379 ER - TY - JOUR A1 - Heuermann, Holger A1 - Rumiantsev, A. A1 - Schott, S. T1 - Advanced on-wafer multiport calibration methods for mono- and mixed-mode device characterization JF - On wafer characterization : 63rd ARFTG conference digest, spring 2004, 11 June 2004, Fort Worth, TX / Automatic RF Techniques Group. [Conference chair: John Cable. Publication chair: J. G. Burns] Y1 - 2004 SN - 0-7803-8371-0 N1 - Microwave Theory and Techniques Society. ; Automatic RF Techniques Group ; ARFTG conference ; (63 : ; 2004.06.11 : ; Fort Worth, Tex.) SP - 91 EP - 96 PB - IEEE Operations Center CY - Piscataway, NJ ER - TY - JOUR A1 - Hackl, Michael A1 - Müller, Lars-Peter A1 - Staat, Manfred A1 - Kahmann, Stephanie Lucina A1 - Wegmann, Kilian T1 - Proximal phalangeal neck fractures of the hand — a biomechanical comparison of three fixation techniques JF - Knee surgery, sports traumatology, arthroscopy N2 - Plate osteosynthesis of displaced proximal phalangeal neck fractures of the hand allows early mobilization due to a stable internal fixation. Nevertheless, joint stiffness—because of soft tissue irritation—represents a common complication leading to high complication rates. Del Pinal et al. recently reported promising clinical results for a new, minimally invasive fixation technique with a cannulated headless intramedullary compression screw. Hence, the aim of this study was to compare plate fixation of proximal phalangeal neck fractures to less two less invasive techniques: Crossed k-wire fixation and intramedullary screw fixation. We hypothesized that these fixation techniques provide inferior stability when compared to plate osteosynthesis. Y1 - 2016 U6 - https://doi.org/10.1007/s00167-016-4080-7 SN - 0942-2056 VL - Volume 24 IS - Supplement 1 SP - 148 EP - 149 PB - Springer CY - Berlin ER - TY - JOUR A1 - Buniatyan, V. A1 - Huck, Christina A1 - Poghossian, Arshak A1 - Aroutiounian, V. M. A1 - Schöning, Michael Josef T1 - BaxSr1-x TiO3/pc-Si heterojunction JF - Armenian journal of physics Y1 - 2013 SN - 1829-1171 VL - 6 IS - 4 SP - 177 EP - 187 PB - National Academy of Sciences of Armenia CY - Yerevan ER - TY - JOUR A1 - Yoshinobu, T. A1 - Ecken, H. A1 - Poghossian, Arshak A1 - Lüth, H. A1 - Iwasaki, H. A1 - Schöning, Michael Josef T1 - Alternative sensor materials for light-addressable potentiometric sensors JF - Sensors and Actuators B. 76 (2001), H. 1-3 Y1 - 2001 SN - 0925-4005 SP - 388 EP - 392 ER - TY - JOUR A1 - Heuermann, Holger A1 - Erkens, Holger T1 - Blocking structures for mixed-mode systems. / Erkens, Holger ; Heuermann, Holger JF - Conference proceedings : Tuesday 12th, Wednesday 13th and Thursday 14th October, [RAI International Exhibition and Congress Centre, Amsterdam ; part of European Microwave Week 2004] / EuMA, European Microwave Association. Vol. 1 Y1 - 2004 SN - 1-580-53992-0 N1 - European Microwave Conference ; (34, 2004, Amsterdam) ; European Microwave Week ; (7, 2004, Amsterdam) SP - 297 EP - 300 PB - Horizon House Publ. CY - London ER - TY - JOUR A1 - Poghossian, Arshak A1 - Abouzar, Maryam H. A1 - Sakkari, M. A1 - Kassab, T. A1 - Han, Y. A1 - Ingebrandt, S. A1 - Offenhäusser, A. A1 - Schöning, Michael Josef T1 - Field-effect sensors for monitoring the layer-by-layer adsorption of charged macromolecules JF - Sensors and Actuators B: Chemical. 118 (2006), H. 1-2 Y1 - 2006 SN - 0925-4005 N1 - Eurosensors XIX - Eurosensors XIX - The 19th European Conference on Solid-State Transducers SP - 163 EP - 170 ER - TY - JOUR A1 - Linder, Peter A1 - Beckler, Matthias A1 - Doerr, Leo A1 - Stoelzle-Feix, Sonja A1 - Fertig, Niels A1 - Jung, Alexander A1 - Staat, Manfred A1 - Gossmann, Matthias T1 - A new in vitro tool to investigate cardiac contractility under physiological mechanical conditions JF - Journal of Pharmacological and Toxicological Methods Y1 - 2019 U6 - https://doi.org/10.1016/j.vascn.2019.05.162 SN - 1056-8719 VL - 99 IS - Article number 106595 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Ludowicy, Jonas A1 - Rings, René A1 - Finger, Felix A1 - Braun, Carsten A1 - Bil, Cees T1 - Impact of Propulsion Technology Levels on the Sizing and Energy Consumption for Serial HybridElectric General Aviation Aircraft T2 - Asia Pacific International Symposium on Aerospace Technology. APISAT 2019 Y1 - 2019 ER - TY - JOUR A1 - Linder, Peter A1 - Digel, Ilya A1 - Temiz Artmann, Aysegül A1 - Kayser, Peter A1 - Porst, Dariusz A1 - Artmann, Gerhard T1 - High-throughput testing of mechanical forces generated in thin cell and tissue layers JF - Tissue Engineering. 13 (2007), H. 7 Y1 - 2007 SN - 1076-3279 N1 - Meeting abstract 433 SP - 1778 EP - 1778 ER - TY - JOUR A1 - Heuermann, Holger A1 - Schiek, Burkhard T1 - A Fast and Robust Procedure for the Determination of the Scattering Parameters for Network Analyzer Calibration Y1 - 1992 N1 - Precision electromagnetic measurements : conference Paris, 9-12 June 1992 = Conférence sur les Mesures Electromagnétiques de Précision. SP - 373 EP - 374 CY - Paris ER - TY - CHAP A1 - Sattler, Johannes Christoph A1 - Alexopoulos, Spiros A1 - Chico Caminos, Ricardo Alexander A1 - Mitchell, John C. A1 - Ruiz, Victor C. A1 - Kalogirou, Soteris A1 - Ktistis, Panayiotis K. A1 - Teixeira Boura, Cristiano José A1 - Herrmann, Ulf T1 - Dynamic simulation model of a parabolic trough collector system with concrete thermal energy storage for process steam generation T2 - AIP Conference Proceedings Y1 - 2019 U6 - https://doi.org/10.1063/1.5117663 SN - 0094243X VL - 2126 SP - 150007-1 EP - 150007-8 ER - TY - JOUR A1 - Krämer, Melina A1 - Pita, Marcos A1 - Zhou, Jian A1 - Ornatska, Maryna A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Katz, Evgeny T1 - Coupling of Biocomputing Systems with Electronic Chips: Electronic Interface for Transduction of Biochemical Information JF - Journal of Physical Chemistry C: Nanomaterials and Interfaces. 113 (2009), H. 6 Y1 - 2009 SN - 1932-7455 SP - 2573 EP - 2579 PB - American Cemical Society CY - Washington, DC ER - TY - JOUR A1 - Huck, Christina A1 - Jolly, Christina A1 - Wagner, Patrick A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - One-chip integrated dual amperometric/field-effect sensor for the detection of dissolved hydrogen JF - Procedia Engineering. 25 (2011) Y1 - 2011 SN - 1877-7058 N1 - EurosensorsXXV ; Proc. Eurosensors XXV, September 4-7, 2011, Athens, Greece SP - 1161 EP - 1164 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Göttsche, Joachim A1 - Korn, Michael A1 - Amato, Alexandre T1 - The Passivhaus concept for the Arabian Peninsula – An energetic-economical evaluation considering the thermal comfort T2 - QScience Proceedings: Vol 2015 N2 - The Passivhaus building standard is a concept developed for the realization of energy-efficient and economical buildings with a simultaneous high utilization comfort under European climate conditions. Major elements of the Passivhaus concept are a high thermal insulation of the external walls, the use of heat and/or solar shading glazing as well as an airtight building envelope in combination with energy-efficient technical building installations and heating or cooling generators, such as an efficient energy-recovery in the building air-conditioning. The objective of this research project is the inquiry to determine the parameters or constraints under which the Passivhaus concept can be implemented under the arid climate conditions in the Arabian Peninsula to achieve an energy-efficient and economical building with high utilization comfort. In cooperation between the Qatar Green Building Council (QGBC), Barwa Real Estate (BRE) and Kahramaa the first Passivhaus was constructed in Qatar and on the Arabian Peninsula in 2013. The Solar-Institut Jülich of Aachen University of Applied Science supports the Qatar Green Building Council with a dynamic building and equipment simulation of the Passivhaus and the neighbouring reference building. This includes simulation studies with different component configurations for the building envelope and different control strategies for heating or cooling systems as well as the air conditioning of buildings to find an energetic-economical optimum. Part of these analyses is the evaluation of the energy efficiency of the used energy recovery system in the Passivhaus air-conditioning and identification of possible energy-saving effects by the use of a bypass function integrated in the heat exchanger. In this way it is expected that on an annual basis the complete electricity demand of the building can be covered by the roof-integrated PV generator. Y1 - 2015 U6 - https://doi.org/10.5339/qproc.2015.qgbc.38 N1 - 10.5339/qproc.2015.qgbc.38 = abstract - Qatar Green Building Conference 2015 - The Vision, 38. ER - TY - JOUR A1 - Wu, Chunsheng A1 - Bronder, Thomas A1 - Poghossian, Arshak A1 - Werner, Frederik A1 - Bäcker, Matthias A1 - Schöning, Michael Josef T1 - Label-free electrical detection of DNA with a multi-spot LAPS: First step towards light-addressable DNA chips JF - Physica status solidi A : Applications and materials science N2 - A multi-spot (4 × 4 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al–p-Si–SiO2 structure has been applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. Single-stranded probe ssDNA molecules (20 bases) were covalently immobilized onto the silanized SiO2 gate surface. The unspecific adsorption of mismatch ssDNA on the MLAPS gate surface was blocked by bovine serum albumin molecules. To reduce the screening effect and to achieve a high sensor signal, the measurements were performed in a low ionic-strength solution. The photocurrent–voltage (I–V) curves were simultaneously recorded on all 16 spots after each surface functionalization step. Large shifts of I–V curves of 25 mV were registered after the DNA immobilization and hybridization event. In contrast, a small potential shift (∼5 mV) was observed in case of mismatch ssDNA, revealing good specificity of the sensor. The obtained results demonstrate the potential of the MLAPS as promising transducer platform for the multi-spot label-free electrical detection of DNA molecules by their intrinsic molecular charge. Y1 - 2014 U6 - https://doi.org/10.1002/pssa.201330442 SN - 1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print) VL - 211 IS - 6 SP - 1423 EP - 1428 PB - Wiley-VCH CY - Weinheim ER - TY - CHAP A1 - Anthrakidis, Anette A1 - Herrmann, Ulf A1 - Schorn, Christian A1 - Schwarzer, Klemens A1 - Wedding, Philipp A1 - Weis, Fabian T1 - Development and Testing of a Novel Method for the Determination of the Efficiency of Concentrating Solar Thermal Collectors T2 - Conference Proceedings Solar World Congress 2015, Daegu, Korea, 08 – 12 November 2015 Y1 - 2015 ER - TY - JOUR A1 - Ferrein, Alexander A1 - Fritz, Christian A1 - Lakemeyer, Gerhard T1 - On-Line Decision-Theoretic Golog for Unpredictable Domains / Ferrein, Alexander ; Fritz, Christian ; Lakemeyer, Gerhard JF - KI 2004: Advances in Artificial Intelligence : 27th Annual German Conference on AI, KI 2004, Ulm, Germany, September 20-24, 2004. Proceedings Y1 - 2004 N1 - Lecture Notes in Computer Science ; 3238 SP - 322 EP - 336 PB - Springer CY - Berlin ER - TY - CHAP A1 - Näther, Niko A1 - Poghossian, Arshak A1 - Platen, J. A1 - Yoshinobu, T. A1 - Koudelka-Hep, M. A1 - Schöning, Michael Josef T1 - Multi-parameter sensing of both physical and (bio-)chemical quantities using the same transducer principle T2 - Biochemical sensing utilisation of micro- and nanotechnologies : Warsaw, [23rd - 26th] November 2005 / ed. by M. Mascini ... Y1 - 2006 SP - 172 EP - 181 CY - Warsaw ER - TY - JOUR A1 - Poghossian, Arshak A1 - Jablonski, Melanie A1 - Molinnus, Denise A1 - Wege, Christina A1 - Schöning, Michael Josef T1 - Field-Effect Sensors for Virus Detection: From Ebola to SARS-CoV-2 and Plant Viral Enhancers JF - Frontiers in Plant Science N2 - Coronavirus disease 2019 (COVID-19) is a novel human infectious disease provoked by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, no specific vaccines or drugs against COVID-19 are available. Therefore, early diagnosis and treatment are essential in order to slow the virus spread and to contain the disease outbreak. Hence, new diagnostic tests and devices for virus detection in clinical samples that are faster, more accurate and reliable, easier and cost-efficient than existing ones are needed. Due to the small sizes, fast response time, label-free operation without the need for expensive and time-consuming labeling steps, the possibility of real-time and multiplexed measurements, robustness and portability (point-of-care and on-site testing), biosensors based on semiconductor field-effect devices (FEDs) are one of the most attractive platforms for an electrical detection of charged biomolecules and bioparticles by their intrinsic charge. In this review, recent advances and key developments in the field of label-free detection of viruses (including plant viruses) with various types of FEDs are presented. In recent years, however, certain plant viruses have also attracted additional interest for biosensor layouts: Their repetitive protein subunits arranged at nanometric spacing can be employed for coupling functional molecules. If used as adapters on sensor chip surfaces, they allow an efficient immobilization of analyte-specific recognition and detector elements such as antibodies and enzymes at highest surface densities. The display on plant viral bionanoparticles may also lead to long-time stabilization of sensor molecules upon repeated uses and has the potential to increase sensor performance substantially, compared to conventional layouts. This has been demonstrated in different proof-of-concept biosensor devices. Therefore, richly available plant viral particles, non-pathogenic for animals or humans, might gain novel importance if applied in receptor layers of FEDs. These perspectives are explained and discussed with regard to future detection strategies for COVID-19 and related viral diseases. Y1 - 2020 U6 - https://doi.org/10.3389/fpls.2020.598103 VL - 11 IS - Article 598103 SP - 1 EP - 14 PB - Frontiers CY - Lausanne ER - TY - JOUR A1 - Bialonski, Stephan A1 - Horstmann, Marie-Therese A1 - Lehnertz, Klaus T1 - From brain to earth and climate systems: Small-world interaction networks or not? JF - Chaos: An Interdisciplinary Journal of Nonlinear Science N2 - We consider recent reports on small-world topologies of interaction networks derived from the dynamics of spatially extended systems that are investigated in diverse scientific fields such as neurosciences, geophysics, or meteorology. With numerical simulations that mimic typical experimental situations, we have identified an important constraint when characterizing such networks: indications of a small-world topology can be expected solely due to the spatial sampling of the system along with the commonly used time series analysis based approaches to network characterization. Y1 - 2010 U6 - https://doi.org/10.1063/1.3360561 SN - 1089-7682 VL - 20 IS - 1 PB - AIP Publishing CY - Melville, NY ER - TY - JOUR A1 - Weigand, Christoph T1 - Economically Optimal Adaptive Inspection Policies JF - Economic Quality Control. 15 (2000), H. 1/2 Y1 - 2000 SN - 0940-5151 N1 - Printausgabe vorhanden: 43 Z 711 SP - 55 EP - 77 ER - TY - CHAP A1 - Heitzer, M. A1 - Staat, Manfred T1 - Direct FEM approach to design-by-analysis of pressurized components N2 - Abstracts of the ACHEMA 2000 - International Meeting on Chemical Engineering, Environmental Protection and Biotechnology, May 22 - 27, 2000. Frankfurt am Main. Achema 2000 : special edition / Linde. [Ed.: Linde AG. Red.: Volker R. Leski]. - Wiesbaden : Linde AG, 2000. - 56 p. : Ill., . - pp: 79 - 81 N2 - Abstracts der ACHEMA 2000 - International Meeting on Chemical Engineering, Environmental Protection and Biotechnology, May 22 - 27, 2000. Frankfurt am Main. KW - Finite-Elemente-Methode KW - Finite-Elemente-Methode KW - limit analysis KW - shakedown analysis Y1 - 2000 ER - TY - CHAP A1 - Alhwarin, Faraj A1 - Ferrein, Alexander A1 - Scholl, Ingrid T1 - IR stereo kinect: improving depth images by combining structured light with IR stereo T2 - PRICAI 2014: Trends in artificial intelligence : 13th Pacific Rim International Conference on Artificial Intelligence : Gold Coast, QLD, Australia, December 1-5, 2014 : proceedings. (Lecture notes in computer science ; vol. 8862) N2 - RGB-D sensors such as the Microsoft Kinect or the Asus Xtion are inexpensive 3D sensors. A depth image is computed by calculating the distortion of a known infrared light (IR) pattern which is projected into the scene. While these sensors are great devices they have some limitations. The distance they can measure is limited and they suffer from reflection problems on transparent, shiny, or very matte and absorbing objects. If more than one RGB-D camera is used the IR patterns interfere with each other. This results in a massive loss of depth information. In this paper, we present a simple and powerful method to overcome these problems. We propose a stereo RGB-D camera system which uses the pros of RGB-D cameras and combine them with the pros of stereo camera systems. The idea is to utilize the IR images of each two sensors as a stereo pair to generate a depth map. The IR patterns emitted by IR projectors are exploited here to enhance the dense stereo matching even if the observed objects or surfaces are texture-less or transparent. The resulting disparity map is then fused with the depth map offered by the RGB-D sensor to fill the regions and the holes that appear because of interference, or due to transparent or reflective objects. Our results show that the density of depth information is increased especially for transparent, shiny or matte objects. Y1 - 2014 SN - 978-3-319-13559-5 (Print) ; 978-3-319-13560-1 (E-Book) U6 - https://doi.org/10.1007/978-3-319-13560-1_33 SP - 409 EP - 421 PB - Springer CY - München ER - TY - CHAP A1 - Bung, Daniel Bernhard A1 - Langohr, Phillip A1 - Waldenberger, Lisa ED - Habersack, Helmut ED - Tritthart, Michael T1 - Influence of cycle number in CFD studies of labyrinth weirs T2 - Proceedings of the 40th IAHR World Congress (Vienna, 2023) N2 - The major advantage of labyrinth weirs over linear weirs is hydraulic efficiency. In hydraulic modeling efforts, this strength contrasts with limited pump capacity as well as limited computational power for CFD simulations. For the latter, reducing the number of investigated cycles can significantly reduce necessary computational time. In this study, a labyrinth weir with different cycle numbers was investigated. The simulations were conducted in FLOW-3D HYDRO as a Large Eddy Simulation. With a mean deviation of 1.75 % between simulated discharge coefficients and literature design equations, a reasonable agreement was found. For downstream conditions, overall consistent results were observed as well. However, the orientation of labyrinth weirs with a single cycle should be chosen carefully under consideration of the individual research purpose. KW - CFD KW - Large Eddy Simulation KW - Labyfrinth weirs Y1 - 2023 SN - 978-90-833476-1-5 U6 - https://doi.org/10.3850/978-90-833476-1-5_iahr40wc-p0531-cd SN - L 2521-7119 (online) N1 - Vienna, Austria, from August 21 to 25, 2023 PB - International Association for Hydro-Environment Engineering and Research (IAHR) CY - Madrid ER - TY - JOUR A1 - Al-Kaidy, Huschyar A1 - Duwe, Anna A1 - Huster, Manuel A1 - Muffler, Kai A1 - Schlegel, Christin A1 - Tim, Sieker A1 - Stadtmüller, Ralf A1 - Tippkötter, Nils A1 - Ulber, Roland T1 - Biotechnology and bioprocess engineering – from the first ullmann's article to recent trends JF - ChemBioEng Reviews N2 - For several thousand years, biotechnology and its associated technical processes have had a great impact on the development of mankind. Based on empirical methods, in particular for the production of foodstuffs and daily commodities, these disciplines have become one of the most innovative future issues. Due to the increasing detailed understanding of cellular processes, production strains can now be optimized. In combination with modern bioprocesses, a variety of bulk and fine chemicals as well as pharmaceuticals can be produced efficiently. In this article, some of the current trends in biotechnology are discussed. Y1 - 2015 U6 - https://doi.org/10.1002/cben.201500008 VL - 2 IS - 3 SP - 175 EP - 184 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Schindler, Kaspar A. A1 - Bialonski, Stephan A1 - Horstmann, Marie-Therese A1 - Elger, Christian E. A1 - Lehnertz, Klaus T1 - Evolving functional network properties and synchronizability during human epileptic seizures JF - Chaos: An Interdisciplinary Journal of Nonlinear Science Y1 - 2008 U6 - https://doi.org/10.1063/1.2966112 SN - 1089-7682 VL - 18 IS - 3 SP - 033119 ER - TY - CHAP A1 - Heuermann, Holger A1 - Finger, Torsten T1 - 2.45 GHz Plasma Powered Spark Plug by Thermal and EM-Optimization Y1 - 2014 N1 - Ansys High Frequency Simulation Conference - AHFSC 2014, Munich; 02/2014 ER - TY - JOUR A1 - Weigand, Christoph T1 - On the Effects of SPC on Production Time JF - Economic Quality Control. 8 (1993) Y1 - 1993 SN - 0940-5151 SP - 23 EP - 61 ER - TY - JOUR A1 - Heuermann, Holger A1 - Emmrich, Thomas A1 - Bongartz, Simon T1 - Microwave spark plug to support ignitions with high compression ratios JF - IEEE Transactions on Plasma Science N2 - Upcoming gasoline engines should run with a larger number of fuels beginning from petrol over methanol up to gas by a wide range of compression ratios and a homogeneous charge. In this article, the microwave (MW) spark plug, based on a high-speed frequency hopping system, is introduced as a solution, which can support a nitrogen compression ratio up to 1:39 in a chamber and more. First, an overview of the high-speed frequency hopping MW ignition and operation system as well as the large number of applications are presented. Both gives an understanding of this new base technology for MW plasma generation. Focus of the theoretical part is the explanation of the internal construction of the spark plug, on the achievable of the high voltage generation as well as the high efficiency to hold the plasma. In detail, the development process starting with circuit simulations and ending with the numerical multiphysics field simulations is described. The concept is evaluated with a reference prototype covering the frequency range between 2.40 and 2.48 GHz and working over a large power range from 20 to 200 W. A larger number of different measurements starting by vector hot-S11 measurements and ending by combined working scenarios out of hot temperature, high pressure and charge motion are winding up the article. The limits for the successful pressure tests were given by the pressure chamber. Pressures ranged from 1 to 39 bar and charge motion up to 25 m/s as well as temperatures from 30◦ to 125◦. KW - Automotive application KW - ignition KW - microplasma KW - microwave (MW) plasma KW - plasma jet Y1 - 2022 U6 - https://doi.org/10.1109/TPS.2022.3183690 SN - 1939-9375 IS - Early Access SP - 1 EP - 6 PB - IEEE ER - TY - JOUR A1 - Schusser, Sebastian A1 - Leinhos, Marcel A1 - Bäcker, Matthias A1 - Poghossian, Arshak A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Impedance spectroscopy: A tool for real-time in situ monitoring of the degradation of biopolymers JF - Physica Status Solidi (A) N2 - Investigation of the degradation kinetics of biodegradable polymers is essential for the development of implantable biomedical devices with predicted biodegradability. In this work, an impedimetric sensor has been applied for real-time and in situ monitoring of degradation processes of biopolymers. The sensor consists of two platinum thin-film electrodes covered by a polymer film to be studied. The benchmark biomedical polymer poly(D,L-lactic acid) (PDLLA) was used as a model system. PDLLA films were deposited on the sensor structure from a polymer solution by using the spin-coating method. The degradation kinetics of PDLLA films have been studied in alkaline solutions of pH 9 and 12 by means of an impedance spectroscopy (IS) method. Any changes in a polymer capacitance/resistance induced by water uptake and/or polymer degradation will modulate the global impedance of the polymer-covered sensor that can be used as an indicator of the polymer degradation. The degradation rate can be evaluated from the time-dependent impedance spectra. As expected, a faster degradation has been observed for PDLLA films exposed to pH 12 solution. Y1 - 2013 U6 - https://doi.org/10.1002/pssa.201200941 SN - 1521-396X ; 0031-8965 VL - 210 IS - 5 SP - 905 EP - 910 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Poth, Sebastian A1 - Monzon, Magaly A1 - Tippkötter, Nils A1 - Ulber, Roland T1 - Lignocellulosic biorefinery: Process integration of hydrolysis and fermentation (SSF process) JF - Holzforschung N2 - The aim of the present work is the process integration and the optimization of the enzymatic hydrolysis of wood and the following fermentation of the products to ethanol. The substrate is a fiber fraction obtained by organosolv pre-treatment of beech wood. For the ethanol production, a co-fermentation by two different yeasts (Saccharomyces cerevisiae and Pachysolen tannophilus) was carried out to convert glucose as well as xylose. Two approaches has been followed: 1. A two step process, in which the hydrolysis of the fiber fraction and the fermentation to product are separated from each other. 2. A process, in which the hydrolysis and the fermentation are carried out in one single process step as simultaneous saccharification and fermentation (SSF). Following the first approach, a yield of about 0.15 g ethanol per gram substrate can be reached. Based on the SSF, one process step can be saved, and additionally, the gained yield can be raised up to 0.3 g ethanol per gram substrate. Y1 - 2011 N1 - 11th EWLP, Hamburg, Germany, August 16–19, 2010 VL - 65 IS - 5 SP - 633 EP - 637 PB - De Gruyter CY - Berlin ER - TY - CHAP A1 - Gömmel, Andreas A1 - Niendorf, Thoralf A1 - Frauenrath, Tobias A1 - Otten, Mario A1 - Butenweg, Christoph A1 - Kob, Malte T1 - 3D vocal fold geometry mapping using Magnetic Resonance Imaging T2 - Fortschritte der Akustik : 36. Deutsche Jahrestagung für Akustik, Band 1 Y1 - 2010 SN - 978-3-9808659-8-2 N1 - Fortschritte der Akustik : 36. Deutsche Jahrestagung für Akustik ; 15.-18. März 2010, Berlin SP - 271 EP - 272 PB - Deutsche Gesellschaft für Akustik CY - Berlin ER -