TY  - JOUR
A1  - Poghossian, Arshak
A1  - Welden, Rene
A1  - Buniatyan, Vahe V.
A1  - Schöning, Michael Josef
T1  - An Array of On-Chip Integrated, Individually Addressable Capacitive Field-Effect Sensors with Control Gate: Design and Modelling
JF  - Sensors
N2  - The on-chip integration of multiple biochemical sensors based on field-effect electrolyte-insulator-semiconductor capacitors (EISCAP) is challenging due to technological difficulties in realization of electrically isolated EISCAPs on the same Si chip. In this work, we present a new simple design for an array of on-chip integrated, individually electrically addressable EISCAPs with an additional control gate (CG-EISCAP). The existence of the CG enables an addressable activation or deactivation of on-chip integrated individual CG-EISCAPs by simple electrical switching the CG of each sensor in various setups, and makes the new design capable for multianalyte detection without cross-talk effects between the sensors in the array. The new designed CG-EISCAP chip was modelled in so-called floating/short-circuited and floating/capacitively-coupled setups, and the corresponding electrical equivalent circuits were developed. In addition, the capacitance-voltage curves of the CG-EISCAP chip in different setups were simulated and compared with that of a single EISCAP sensor. Moreover, the sensitivity of the CG-EISCAP chip to surface potential changes induced by biochemical reactions was simulated and an impact of different parameters, such as gate voltage, insulator thickness and doping concentration in Si, on the sensitivity has been discussed.
KW  - equivalent circuit
KW  - multianalyte detection
KW  - control gate
KW  - on-chip integrated addressable EISCAP sensors
KW  - capacitive field-effect sensor
Y1  - 2021
U6  - http://dx.doi.org/10.3390/s21186161
SN  - 1424-8220
N1  - This article belongs to the Special Issue "Field-Effect Sensors: From pH Sensing to Biosensing"
VL  - 21
IS  - 18
SP  - 17
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Vahidpour, Farnoosh
A1  - Alghazali, Yousef
A1  - Akca, Sevilay
A1  - Hommes, Gregor
A1  - Schöning, Michael Josef
T1  - An Enzyme-Based Interdigitated Electrode-Type Biosensor for Detecting Low Concentrations of H₂O₂ Vapor/Aerosol
JF  - Chemosensors
N2  - This work introduces a novel method for the detection of H₂O₂ vapor/aerosol of low concentrations, which is mainly applied in the sterilization of equipment in medical industry. Interdigitated electrode (IDE) structures have been fabricated by means of microfabrication techniques. A differential setup of IDEs was prepared, containing an active sensor element (active IDE) and a passive sensor element (passive IDE), where the former was immobilized with an enzymatic membrane of horseradish peroxidase that is selective towards H₂O₂. Changes in the IDEs’ capacitance values (active sensor element versus passive sensor element) under H₂O₂ vapor/aerosol atmosphere proved the detection in the concentration range up to 630 ppm with a fast response time (<60 s). The influence of relative humidity was also tested with regard to the sensor signal, showing no cross-sensitivity. The repeatability assessment of the IDE biosensors confirmed their stable capacitive signal in eight subsequent cycles of exposure to H₂O₂ vapor/aerosol. Room-temperature detection of H₂O₂ vapor/aerosol with such miniaturized biosensors will allow a future three-dimensional, flexible mapping of aseptic chambers and help to evaluate sterilization assurance in medical industry.
Y1  - 2022
U6  - http://dx.doi.org/10.3390/chemosensors10060202
SN  - 2227-9040
N1  - This article belongs to the Special Issue "Bioinspired Chemical Sensors and Micro-Nano Devices"
VL  - 10
IS  - 6
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Moseley, Fiona
A1  - Halamek, Jan
A1  - Kramer, Friederike
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Katz, Evgeny
T1  - An enzyme-based reversible CNOT logic gate realized in a flow system
JF  - Analyst
N2  - An enzyme system organized in a flow device was used to mimic a reversible Controlled NOT (CNOT) gate with two input and two output signals. Reversible conversion of NAD⁺ and NADH cofactors was used to perform a XOR logic operation, while biocatalytic hydrolysis of p-nitrophenyl phosphate resulted in an Identity operation working in parallel. The first biomolecular realization of a CNOT gate is promising for integration into complex biomolecular networks and future biosensor/biomedical applications.
Y1  - 2014
U6  - http://dx.doi.org/10.1039/C4AN00133H
SN  - 1364-5528 (E-Journal) ; 0003-2654 (Print)
VL  - 139
IS  - 8
SP  - 1839
EP  - 1842
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Honarvarfard, Elham
A1  - Gamella, Maria
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Katz, Evgeny
T1  - An enzyme-based reversible Controlled NOT (CNOT) logic gate operating on a semiconductor transducer
JF  - Applied Materials Today
N2  - An enzyme-based biocatalytic system mimicking operation of a logically reversible Controlled NOT (CNOT) gate has been interfaced with semiconductor electronic transducers. Electrolyte–insulator–semiconductor (EIS) structures have been used to transduce chemical changes produced by the enzyme system to an electronically readable capacitive output signal using field-effect features of the EIS device. Two enzymes, urease and esterase, were immobilized on the insulating interface of EIS structure producing local pH changes performing XOR logic operation controlled by various combinations of the input signals represented by urea and ethyl butyrate. Another EIS transducer was functionalized with esterase only, thus performing Identity (ID) logic operation for the ethyl butyrate input. Both semiconductor devices assembled in parallel operated as a logically reversible CNOT gate. The present system, despite its simplicity, demonstrated for the first time logically reversible function of the enzyme system transduced electronically with the semiconductor devices. The biomolecular realization of a CNOT gate interfaced with semiconductors is promising for integration into complex biomolecular networks and future biosensor/biomedical applications.
KW  - Electrolyte–insulator–semiconductor
KW  - Capacitive field-effect
KW  - CNOT
KW  - XOR
KW  - Enzyme logic gate
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.apmt.2017.08.003
SN  - 2352-9407
VL  - 9
SP  - 266
EP  - 270
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schütz, S.
A1  - Schöning, Michael Josef
A1  - Schroth, P.
A1  - Weißbecker, B.
A1  - Kordos, P.
A1  - Lüth, H.
A1  - Hummel, Hans E.
T1  - An insectbased BioFET as a bioelectronic nose
JF  - Sensors and Actuators B. 65 (2000), H. 1-3
Y1  - 2000
SN  - 0925-4005
SP  - 291
EP  - 295
ER  - 
TY  - JOUR
A1  - Schütz, S.
A1  - Schöning, Michael Josef
A1  - Schroth, P.
A1  - Weißbecker, B.
A1  - Kordos, P.
A1  - Lüth, H.
A1  - Hummel, Hans E.
T1  - An insectbased BioFET as a bioelectronic nose
JF  - Proceedings of the Seventh International Meeting on Chemical Sensors : 27 - 30 July, 1998, Beijing, P. R. China / ed. Zhi-Gang Zhou
Y1  - 1998
N1  - International Meeting on Chemical Sensors ; (7, 1998, Beijing) ; International Meeting on Chemical Sensors (IMCS) ; (7 : ; 1998.07.27-30 : ; Beijing)
SP  - 314
EP  - 316
PB  - Elsevier
CY  - Amsterdam [u.a.]
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Schroth, P.
A1  - Simonis, A.
A1  - Lüth, H.
T1  - An ISFET-based penicillin sensor with high sensitivity, low detection limit and long lifetime
JF  - Sensors and Actuators B. 76 (2001), H. 1-3
Y1  - 2001
SN  - 0925-4005
SP  - 519
EP  - 526
ER  - 
TY  - JOUR
A1  - Murib, Mohammed S.
A1  - Tran, Anh Quang
A1  - Ceuninck, Ward de
A1  - Schöning, Michael Josef
A1  - Nesladek, Milos
A1  - Serpengüzel, Ali
A1  - Wagner, Patrick
T1  - Analysis of an optical biosensor based on elastic light scattering from diamond-, glass-, and sapphire microspheres
JF  - Physica Status Solidi A
N2  - Deoxyribonucleic acid (DNA) and protein recognition are now standard tools in biology. In addition, the special optical properties of microsphere resonators expressed by the high quality factor (Q-factor) of whispering gallery modes (WGMs) or morphology dependent resonances (MDRs) have attracted the attention of the biophotonic community. Microsphere-based biosensors are considered as powerful candidates to achieve label-free recognition of single molecules due to the high sensitivity of their WGMs. When the microsphere surface is modified with biomolecules, the effective refractive index and the effective size of the microsphere change resulting in a resonant wavelength shift. The transverse electric (TE) and the transverse magnetic (TM) elastic light scattering intensity of electromagnetic waves at 600 and 1400 nm are numerically calculated for DNA and unspecific binding of proteins to the microsphere surface. The effect of changing the optical properties was studied for diamond (refractive index 2.34), glass (refractive index 1.50), and sapphire (refractive index 1.75) microspheres with a 50 µm radius. The mode spacing, the linewidth of WGMs, and the shift of resonant wavelength due to the change in radius and refractive index, were analyzed by numerical simulations. Preliminary results of unspecific binding of biomolecules are presented. The calculated shift in WGMs can be used for biomolecules detection.
Y1  - 2012
U6  - http://dx.doi.org/10.1002/pssa.201100795
SN  - 1862-6319
N1  - Special Issue: "Fundamentals and Applications of Diamond"
VL  - 209
IS  - 9
SP  - 1804
EP  - 1810
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Heiden, W.
A1  - Turek, M.
A1  - Schöning, Michael Josef
T1  - Analysis of chemical sensor data
JF  - Proceedings of the 4th Russian-German Workshop "Innovation Information Technologies: Theory and practice" : Ufa, Russia, April 8-13, 2011 / eds. Yupsova, Nafisa ...
Y1  - 2011
SN  - 978-5-4221-0159-7
SP  - 76
EP  - 81
PB  - State Aviation Technical Univ.
CY  - Ufa
ER  - 
TY  - JOUR
A1  - Mourzina, Y. G.
A1  - Ermelenko, Y. E.
A1  - Yoshinobu, T.
A1  - Vlasov, Y.
A1  - Iwasaki, H.
A1  - Schöning, Michael Josef
T1  - Anionselective light-addressable potentiometric sensors (LAPS) for the determination of nitrate and suphate ions
JF  - Sensors and Actuators B. 91 (2003), H. 1-3
Y1  - 2003
SN  - 0925-4005
SP  - 32
EP  - 38
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schultze, J. W.
A1  - Schöning, Michael Josef
T1  - Application of a (bio-)chemical sensor (ISFET) for the detection of physical parameters in liquids
JF  - Electrochimica Acta. 48 (2003), H. 20-22
Y1  - 2003
SP  - 3289
EP  - 3297
ER  - 
TY  - JOUR
A1  - Pilas, Johanna
A1  - Yazici, Y.
A1  - Selmer, Thorsten
A1  - Keusgen, M.
A1  - Schöning, Michael Josef
T1  - Application of a portable multi-analyte biosensor for organic acid determination in silage
JF  - Sensors
N2  - Multi-analyte biosensors may offer the opportunity to perform cost-effective and rapid analysis with reduced sample volume, as compared to electrochemical biosensing of each analyte individually. This work describes the development of an enzyme-based biosensor system for multi-parametric determination of four different organic acids. The biosensor array comprises five working electrodes for simultaneous sensing of ethanol, formate, d-lactate, and l-lactate, and an integrated counter electrode. Storage stability of the biosensor was evaluated under different conditions (stored at +4 °C in buffer solution and dry at −21 °C, +4 °C, and room temperature) over a period of 140 days. After repeated and regular application, the individual sensing electrodes exhibited the best stability when stored at −21 °C. Furthermore, measurements in silage samples (maize and sugarcane silage) were conducted with the portable biosensor system. Comparison with a conventional photometric technique demonstrated successful employment for rapid monitoring of complex media.
Y1  - 2018
U6  - http://dx.doi.org/10.3390/s18051470
SN  - 1424-8220
VL  - 18
IS  - 5
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Miyamato, Ko-ichiro
A1  - Sakakita, Sakura
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Yoshinobu, Tatsuo
T1  - Application of chemical imaging sensor to in-situ pH imaging in the vicinity of a corroding metal surface
JF  - Electrochimica Acta
N2  - The chemical imaging sensor was applied to in-situ pH imaging of the solution in the vicinity of a corroding surface of stainless steel under potentiostatic polarization. A test piece of polished stainless steel was placed on the sensing surface leaving a narrow gap filled with artificial seawater and the stainless steel was corroded under polarization. The pH images obtained during polarization showed correspondence between the region of lower pH and the site of corrosion. It was also found that the pH value in the gap became as low as 2 by polarization, which triggered corrosion.
Y1  - 2015
U6  - http://dx.doi.org/10.1016/j.electacta.2015.07.184
SN  - 0013-4686
VL  - 183
SP  - 137
EP  - 142
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Baade, A.
A1  - Emons, H.
A1  - Schöning, Michael Josef
T1  - Application of ISFET for pH measurements in rain droplets
JF  - Sensors and Actuators B. 76 (2001), H. 1-3
Y1  - 2001
SN  - 0925-4005
SP  - 634
EP  - 638
ER  - 
TY  - JOUR
A1  - Yoshinobu, Tatsuo
A1  - Moritz, Werner
A1  - Finger, Friedhelm
A1  - Schöning, Michael Josef
ED  - Comini, Elisabetta
T1  - Application of thin-film amorphous silicon to chemical imaging
JF  - Nanostructured materials and hybrid composites for gas sensors and biomedical applications : symposium held April 18-20, 2006, San Francisco , California, U.S.A.
Y1  - 2006
SN  - 9781558998711
N1  - Materials Research Society symposia proceedings; v. 915
IS  - Paper 0910-A-20-01
SP  - 1
EP  - 10
ER  - 
TY  - JOUR
A1  - Schütz, S.
A1  - Hummel, Hans E.
A1  - Schöning, Michael Josef
A1  - Schroth, P.
A1  - Kordos, P.
A1  - Lüth, H.
A1  - Zimmermann, S.
A1  - Schwarz, A.
A1  - Kohl, C.-D.
A1  - Koczan, D.
T1  - Applications and perspectives of biosensors based on insect olfaction
JF  - Sensor 99 : proceedings / 9th International Fair and Conference for Sensors, Transducers & Systems, May 18 - 20, 1999, Exhibition Centre Nürnberg/Germany
Y1  - 1999
N1  - Internationale Messe mit Kongreß für Sensoren, Meßaufnehmer & Systeme ; (9, 1999, Nürnberg)
SP  - 99
EP  - 104
PB  - AMA Service
CY  - Wunstorf
ER  - 
TY  - JOUR
A1  - Yoshinobu, T.
A1  - Yasuhito, U.
A1  - Iwasaki, H.
A1  - Näther, Niko
A1  - Schöning, Michael Josef
A1  - Koudelka-Hep, M.
T1  - Applications of the light-addressable potentiometric sensor to microfluidic devices
JF  - Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale].
Y1  - 2004
SN  - 88-7621-282-5
N1  - Eurosensors ; (18, 2004, Roma)
SP  - 434
EP  - 437
CY  - Roma
ER  - 
TY  - JOUR
A1  - Figueroa-Miranda, Gabriela
A1  - Feng, Lingyan
A1  - Shiu, Simon Chi-Chin
A1  - Dirkzwager, Roderick Marshall
A1  - Cheung, Yee-Wai
A1  - Tanner, Julian Alexander
A1  - Schöning, Michael Josef
A1  - Offenhäusser, Andreas
A1  - Mayer, Dirk
T1  - Aptamer-based electrochemical biosensor for highly sensitive and selective malaria detection with adjustable dynamic response range and reusability
JF  - Sensor and Actuators B: Chemical
N2  - Malaria infection remains a significant risk for much of the population of tropical and subtropical areas, particularly in developing countries. Therefore, it is of high importance to develop sensitive, accurate and inexpensive malaria diagnosis tests. Here, we present a novel aptamer-based electrochemical biosensor (aptasensor) for malaria detection by impedance spectroscopy, through the specific recognition between a highly discriminatory DNA aptamer and its target Plasmodium falciparum lactate dehydrogenase (PfLDH). Interestingly, due to the isoelectric point (pI) of PfLDH, the aptasensor response showed an adjustable detection range based on the different protein net-charge at variable pH environments. The specific aptamer recognition allows sensitive protein detection with an expanded detection range and a low detection limit, as well as a high specificity for PfLDH compared to analogous proteins. The specific feasibility of the aptasensor is further demonstrated by detection of the target PfLDH in human serum. Furthermore, the aptasensor can be easily regenerated and thus applied for multiple usages. The robustness, sensitivity, and reusability of the presented aptasensor make it a promising candidate for point-of-care diagnostic systems.
Y1  - 2018
U6  - http://dx.doi.org/10.1016/j.snb.2017.07.117
SN  - 0925-4005
VL  - 255
IS  - P1
SP  - 235
EP  - 243
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Turek, M.
A1  - Heiden, W.
A1  - Riesen, A.
A1  - Chhabda, T. A.
A1  - Schubert, J.
A1  - Krüger, P.
A1  - Keusgen, M.
T1  - Artificial intelligence/fuzzy logic method for analysis of combined signals from heavy metal chemical sensors
JF  - Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI
Y1  - 2009
SN  - 0013-4686
SP  - 6082
EP  - 6088
PB  - Elsevier
CY  - New York
ER  - 
TY  - JOUR
A1  - Vahidpour, Farnoosh
A1  - Guthman, Eric
A1  - Arreola, Julia
A1  - Alghazali, Yousef H. M.
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
T1  - Assessment of Various Process Parameters for Optimized Sterilization Conditions Using a Multi-Sensing Platform
JF  - Foods
N2  - In this study, an online multi-sensing platform was engineered to simultaneously evaluate various process parameters of food package sterilization using gaseous hydrogen peroxide (H₂O₂). The platform enabled the validation of critical aseptic parameters. In parallel, one series of microbiological count reduction tests was performed using highly resistant spores of B. atrophaeus DSM 675 to act as the reference method for sterility validation. By means of the multi-sensing platform together with microbiological tests, we examined sterilization process parameters to define the most effective conditions with regards to the highest spore kill rate necessary for aseptic packaging. As these parameters are mutually associated, a correlation between different factors was elaborated. The resulting correlation indicated the need for specific conditions regarding the applied H₂O₂ gas temperature, the gas flow and concentration, the relative humidity and the exposure time. Finally, the novel multi-sensing platform together with the mobile electronic readout setup allowed for the online and on-site monitoring of the sterilization process, selecting the best conditions for sterility and, at the same time, reducing the use of the time-consuming and costly microbiological tests that are currently used in the food package industry.
KW  - spore kill rate
KW  - sterility
KW  - aseptic parameters
KW  - multi-sensing platform
KW  - gaseous hydrogen peroxide
Y1  - 2022
U6  - http://dx.doi.org/10.3390/foods11050660
SN  - 2304-8158
N1  - This article belongs to the Special Issue "Sensors and Biosensors Application for Food Industries"
VL  - 11
IS  - 5
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Siqueira, José R. Jr.
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Zucolotto, Valtencir
A1  - Oliveira, Osvaldo N. Jr.
A1  - Schöning, Michael Josef
T1  - Associating biosensing properties with the morphological structure of multilayers containing carbon nanotubes on field-effect devices
JF  - Physica status solidi (a). 207 (2010), H. 4
Y1  - 2010
SN  - 1862-6300
N1  - Special Issue: Engineering of Functional Interfaces EnFI 2009
SP  - 781
EP  - 786
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Wagner, H.
A1  - Schöning, Michael Josef
T1  - Automatisiertes „wafer level“-Testsystem zur Charakterisierung von siliziumbasierten Chemo- und Biosensoren
JF  - Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vorträge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in Nürnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA)
Y1  - 2010
SN  - 978-3-8007-3260-9
N1  - Fachtagung Sensoren und Messsysteme 15, 2010, Nürnberg ; Gesellschaft Mess- und Automatisierungstechnik
SP  - 89
EP  - 92
PB  - VDE Verlag
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Buniatyan, V.
A1  - Huck, Christina
A1  - Poghossian, Arshak
A1  - Aroutiounian, V. M.
A1  - Schöning, Michael Josef
T1  - BaxSr1-x TiO3/pc-Si heterojunction
JF  - Armenian journal of physics
Y1  - 2013
SN  - 1829-1171
VL  - 6
IS  - 4
SP  - 177
EP  - 187
PB  - National Academy of Sciences of Armenia
CY  - Yerevan
ER  - 
TY  - JOUR
A1  - Buniatyan, V.
A1  - Huck, Christina
A1  - Poghossian, Arshak
A1  - Aroutiounian, V. M.
A1  - Schöning, Michael Josef
T1  - BaxSr1-x TiO3/pc-Si heterojunction capacitance
JF  - Armenian journal of physics
Y1  - 2013
SN  - 1829-1171
VL  - 6
IS  - 4
SP  - 188
EP  - 197
PB  - National Academy of Sciences of Armenia
CY  - Yerevan
ER  - 
TY  - JOUR
A1  - Werner, Frederik
A1  - Groebel, Simone
A1  - Schuhmacher, K.
A1  - Spelthahn, Heiko
A1  - Wagner, Torsten
A1  - Selmer, Thorsten
A1  - Baumann, Marcus
A1  - Schöning, Michael Josef
T1  - Bestimmung der metabolischen Aktivität von Mikroorganismen während des Biogasbildungsprozesses
JF  - 9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.]
Y1  - 2009
SN  - 978-3-941298-44-6
N1  - Dresdner Sensor-Symposium ; (9, 2009, Dresden)
SP  - 201
EP  - 204
PB  - TUDpress
CY  - Dresden
ER  - 
TY  - CHAP
A1  - Huck, Christina
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Bifunktionaler Sensorchip für den Nachweis von Gelöstwasserstoff
Y1  - 2011
SN  - 978-3942710-53-4
U6  - http://dx.doi.org/10.5162/10dss2011/16.10
SP  - 325
EP  - 328
ER  - 
TY  - JOUR
A1  - Kramer, Friederike
A1  - Halamkova, Lenka
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Katz, Evgeny
A1  - Halamek, Jan
T1  - Biocatalytic analysis of biomarkers for forensic identification of ethnicity between Caucasian and African American
JF  - The analyst. August 2013
Y1  - 2013
SN  - 1364-5528 (E-Journal); 0003-2654 (Print)
VL  - Vol. 138
SP  - 6251
EP  - 6257
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Lüth, H.
A1  - Thust, M.
A1  - Steffen, A.
A1  - Kordos, P.
A1  - Schöning, Michael Josef
T1  - Biochemical sensors with structured and porous silicon capacitors
JF  - Materials Science and Engineering B. 69-70 (2000)
Y1  - 2000
SN  - 0921-5107
SP  - 104
EP  - 108
ER  - 
TY  - JOUR
A1  - Schroth, P.
A1  - Weißbecker, B.
A1  - Schütz, S.
A1  - Ecken, H.
A1  - Yoshinobu, T.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - Bioelectronic signal processing - intact chemoreceptors coupled to field-effect devices
JF  - Lecture Notes of the ICB Seminars
Y1  - 2002
SP  - 28
EP  - 42
PB  - MCB
CY  - Warsaw
ER  - 
TY  - JOUR
A1  - Schroth, P.
A1  - Weißbecker, B.
A1  - Schütz, S.
A1  - Ecken, H.
A1  - Yoshinobu, T.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - Bioelectronic signal processing - intact chemoreceptors coupled to field-effect devices
JF  - Biocybernetics and Biomedical Engineering. 21 (2001), H. 3
Y1  - 2001
SN  - 0208-5216
SP  - 27
EP  - 42
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Poghossian, Arshak
T1  - BioFEDs (field-effect devices) : State-of-the-art and new directions
JF  - Electroanalysis
Y1  - 2006
U6  - http://dx.doi.org/10.1002/elan.200603609
SN  - 1521-4109
VL  - 18
IS  - 19-20
SP  - 1893
EP  - 1900
ER  - 
TY  - CHAP
A1  - Schusser, Sebastian
A1  - Leinhos, Marcel
A1  - Poghossian, Arshak
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
ED  - Abdelghani, Adnane
ED  - Schöning, Michael Josef
T1  - Biopolymer-degradation monitoring by chip-­based impedance spectroscopy technique
T2  - Nanoscale Science and Technology (NS&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012
Y1  - 2012
SP  - 47
EP  - 47
ER  - 
TY  - JOUR
A1  - Keusgen, Michael
A1  - Jünger, Martina
A1  - Krest, Ingo
A1  - Schöning, Michael Josef
T1  - Biosensoric detection of the cysteine sulphoxide alliin
JF  - Sensors and Actuators B. 95 (2003), H. 1-3
Y1  - 2003
SN  - 0925-4005
SP  - 297
EP  - 302
ER  - 
TY  - JOUR
A1  - Keusgen, M.
A1  - Jünger, M.
A1  - Schöning, Michael Josef
T1  - Biosensoric detection of the cysteine sulphoxide alliin
JF  - Book of abstracts / ed. by J. Saneistr.
Y1  - 2002
SN  - 80-01-02576-4
N1  - Eurosensors ; (16, 2002, Praha)
SP  - 1175
EP  - 1178
PB  - Czech Technical University, Faculty of Electrical Engineering, Department of Measurement
CY  - Prague
ER  - 
TY  - JOUR
A1  - Paczkowski, Sebastian
A1  - Weißbecker, Bernhard
A1  - Schöning, Michael Josef
A1  - Schütz, Stefan
T1  - Biosensors on the Basis of Insect Olfaction
JF  - Insect biotechnology / Andreas Vilcinskas, ed.
Y1  - 2011
SN  - 978-90-481-9640-1
N1  - Biologically-inspired system ; 2
SP  - 225
EP  - 240
PB  - Springer
CY  - Dordrecht [u.a.]
ER  - 
TY  - CHAP
A1  - Kirchner, Patrick
A1  - Reisert, Steffen
A1  - Schöning, Michael Josef
T1  - Calorimetric gas sensors for hydrogen peroxide monitoring in aseptic food processes
T2  - Gas sensing fundamentals. (Springer Series on Chemical Sensors and Biosensors ; 15)
N2  - For the sterilisation of aseptic food packages it is taken advantage of the microbicidal properties of hydrogen peroxide (H2O2). Especially, when applied in vapour phase, it has shown high potential of microbial inactivation. In addition, it offers a high environmental compatibility compared to other chemical sterilisation agents, as it decomposes into oxygen and water, respectively. Due to a lack in sensory detection possibilities, a continuous monitoring of the H2O2 concentration was recently not available. Instead, the sterilisation efficacy is validated using microbiological tests. However, progresses in the development of calorimetric gas sensors during the last 7 years have made it possible to monitor the H2O2 concentration during operation. This chapter deals with the fundamentals of calorimetric gas sensing with special focus on the detection of gaseous hydrogen peroxide. A sensor principle based on a calorimetric differential set-up is described. Special emphasis is given to the sensor design with respect to the operational requirements under field conditions. The state-of-the-art regarding a sensor set-up for the on-line monitoring and secondly, a miniaturised sensor for in-line monitoring are summarised. Furthermore, alternative detection methods and a novel multi-sensor system for the characterisation of aseptic sterilisation processes are described.
KW  - Calorimetric gas sensor
KW  - Hydrogen peroxide
KW  - Multi-sensor system
Y1  - 2014
SN  - 978-3-642-54518-4 (Print) ; 978-3-642-54519-1 (Online)
U6  - http://dx.doi.org/10.1007/5346_2013_51
SP  - 279
EP  - 309
PB  - Springer
CY  - Heidelberg
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Mourzina, Y. G.
A1  - Schubert, J.
A1  - Zander, W.
A1  - Legin, A.
A1  - Vlasov, Y. G.
A1  - Lüth, H.
T1  - Can pulsed laser deposition serve as an advanced technique in fabricating chemical sensors?
JF  - Sensors and Actuators B. 78 (2001), H. 1-3
Y1  - 2001
SN  - 0925-4005
N1  - Selected Papers form Eurosensors XIV
SP  - 273
EP  - 278
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Mourzina, Y. G.
A1  - Schubert, J.
A1  - Zander, W.
A1  - Legin, A.
A1  - Vlasov, Y. G.
A1  - Lüth, H.
T1  - Can pulsed laser deposition serve as an advanced technique in fabricating chemical sensors?
JF  - Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...]
Y1  - 2000
SN  - 87-89935-50-0
N1  - Eurosensors ; (14, 2000, København) ; Eurosensors ; (14 : ; 2000.08.27-30 : ; Copenhagen) ; European Conference on Solid-State Transducers ; (14 : ; 2000.08.27-30 : ; Copenhagen)
SP  - 615
EP  - 618
PB  - MIC, Mikroelektronik Centret
CY  - Lyngby, Denmark
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Abouzar, Maryam H.
A1  - Schöning, Michael Josef
T1  - Capacitance–voltage and impedance characteristics of field-effect EIS sensors functionalised with polyelectrolyte multilayers
JF  - IRBM. 29 (2008), H. 2-3
Y1  - 2008
SN  - 1959-0318
SP  - 149
EP  - 154
ER  - 
TY  - JOUR
A1  - Abouzar, Maryam H.
A1  - Werner, Moritz
A1  - Schöning, Michael Josef
A1  - Poghossian, Arshak
T1  - Capacitance–voltage and impedance-spectroscopy characteristics of nanoplate EISOI capacitors
JF  - Physica status solidi (a) : applications and material science. 208 (2011), H. 6
Y1  - 2011
SN  - 1862-6319
SP  - 1327
EP  - 1332
PB  - Wiley-VCH
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Abouzar, Maryam H.
A1  - Poghossian, Arshak
A1  - Siqueira, José R. Jr.
A1  - Oliveira, Osvaldo N. Jr.
A1  - Moritz, Werner
A1  - Schöning, Michael Josef
T1  - Capacitive electrolyte-insulator-semiconductor structures functionalised with a polyelectrolyte/enzyme multilayer: New strategy for enhanced field-effect biosensing
JF  - Physica Status Solidi (A). 207 (2010), H. 4
Y1  - 2010
SN  - 1862-6300
N1  - Special Issue: Engineering of Functional Interfaces EnFI 2009
SP  - 884
EP  - 890
ER  - 
TY  - JOUR
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Abouzar, Maryam H.
A1  - Wenmackers, Sylvia
A1  - Janssens, Stoffel D.
A1  - Haenen, Ken
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Capacitive field-effect (bio-)chemical sensors based on nanocrystalline diamond films
JF  - Diamond Electronics and Bioelectronics — Fundamentals to Applications III, edited by P. Bergonzo, [u.a.]
Y1  - 2010
N1  - MRS Proceedings Volume 1203 paper 1203-J17-31 ; Mater. Res. Soc. Sympos. Proc. Vol 1203 (2010) ; Materials Research Society
SP  - 1
EP  - 6
ER  - 
TY  - JOUR
A1  - Jablonski, Melanie
A1  - Poghossian, Arshak
A1  - Severin, Robin
A1  - Keusgen, Michael
A1  - Wege, Christian
A1  - Schöning, Michael Josef
T1  - Capacitive Field-Effect Biosensor Studying Adsorption of Tobacco Mosaic Virus Particles
JF  - Micromachines
N2  - Plant virus-like particles, and in particular, tobacco mosaic virus (TMV) particles, are increasingly being used in nano- and biotechnology as well as for biochemical sensing purposes as nanoscaffolds for the high-density immobilization of receptor molecules. The sensitive parameters of TMV-assisted biosensors depend, among others, on the density of adsorbed TMV particles on the sensor surface, which is affected by both the adsorption conditions and surface properties of the sensor. In this work, Ta₂O₅-gate field-effect capacitive sensors have been applied for the label-free electrical detection of TMV adsorption. The impact of the TMV concentration on both the sensor signal and the density of TMV particles adsorbed onto the Ta₂O₅-gate surface has been studied systematically by means of field-effect and scanning electron microscopy methods. In addition, the surface density of TMV particles loaded under different incubation times has been investigated. Finally, the field-effect sensor also demonstrates the label-free detection of penicillinase immobilization as model bioreceptor on TMV particles.
KW  - capacitive field-effect sensor
KW  - plant virus detection
KW  - tobacco mosaic virus (TMV)
KW  - TMV adsorption
KW  - Ta₂O₅ gate
Y1  - 2021
U6  - http://dx.doi.org/10.3390/mi12010057
VL  - 12
IS  - 1
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Capacitive field-effect eis chemical sensors and biosensors: A status report
JF  - Sensors
N2  - Electrolyte-insulator-semiconductor (EIS) field-effect sensors belong to a new generation of electronic chips for biochemical sensing, enabling a direct electronic readout. The review gives an overview on recent advances and current trends in the research and development of chemical sensors and biosensors based on the capacitive field-effect EIS structure—the simplest field-effect device, which represents a biochemically sensitive capacitor. Fundamental concepts, physicochemical phenomena underlying the transduction mechanism and application of capacitive EIS sensors for the detection of pH, ion concentrations, and enzymatic reactions, as well as the label-free detection of charged molecules (nucleic acids, proteins, and polyelectrolytes) and nanoparticles, are presented and discussed.
Y1  - 2020
U6  - http://dx.doi.org/10.3390/s20195639
SN  - 1424-8220
VL  - 20
IS  - 19
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Buniatyan, Vahe V.
A1  - Matirosyan, N.
A1  - Abouzar, Maryam H.
A1  - Schubert, J.
A1  - Zander, W.
A1  - Gevorgian, S.
A1  - Schöning, Michael Josef
A1  - Poghossian, Arshak
T1  - Capacitive field-effect pH sensor based on an electrolyte-ferroelectric-insulator-semiconductor structure
JF  - SENSOR 2009 : : 14th International Conference on Sensors, Technologies, Electronics and Applications; Nürnberg, Germany, 26 - 28 May 2009; proceedings; [part of] Sensor + Test Conference 2009 / AMA, Fachverband für Sensorik e.V
Y1  - 2009
SN  - 9783981099355
N1  - AMA, Fachverband für Sensorik ; Sensor International Conference ; (14 : ; 2009.05.26-28 : ; Nürnberg)
SP  - 317
EP  - 322
PB  - AMA Service
CY  - Wunstorf
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Thust, M.
A1  - Kordos, P.
A1  - Schultze, J.W.
A1  - Lüth, H.
T1  - Capacitive microsensors for biochemical sensing based on porous silicon technology
JF  - Transducers '99 : proceedings of the Tenth International Conference on Solid-State Sensors and Actuators ; 7 - 10 June, 1999, Sendai, Japan / ed.: S. Middelhoek
Y1  - 2000
N1  - International Conference on Solid State Sensors and Actuators <10, 1999, Sendai, Miyagi-ken> ; Transducers '99 ; (10 : ; 1999.06.07-10 : ; Sendai)
SP  - 1184
EP  - 1187
PB  - Elsevier
CY  - Amsterdam [u.a.]
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Kurowski, A.
A1  - Thust, M.
A1  - Kordos, P.
A1  - Schultze, J. W.
A1  - Lüth, H.
T1  - Capacitive microsensors for biochemical sensing on porous silicon technology
JF  - Sensors and Actuators B. 64 (2000), H. 1-3
Y1  - 2000
SN  - 0925-4005
SP  - 59
EP  - 64
ER  - 
TY  - JOUR
A1  - Karschuck, Tobias
A1  - Poghossian, Arshak
A1  - Ser, Joey
A1  - Tsokolakyan, Astghik
A1  - Achtsnicht, Stefan
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Capacitive model of enzyme-modified field-effect biosensors: Impact of enzyme coverage
JF  - Sensors and Actuators B: Chemical
N2  - Electrolyte-insulator-semiconductor capacitors (EISCAP) belong to field-effect sensors having an attractive transducer architecture for constructing various biochemical sensors. In this study, a capacitive model of enzyme-modified EISCAPs has been developed and the impact of the surface coverage of immobilized enzymes on its capacitance-voltage and constant-capacitance characteristics was studied theoretically and experimentally. The used multicell arrangement enables a multiplexed electrochemical characterization of up to sixteen EISCAPs. Different enzyme coverages have been achieved by means of parallel electrical connection of bare and enzyme-covered single EISCAPs in diverse combinations. As predicted by the model, with increasing the enzyme coverage, both the shift of capacitance-voltage curves and the amplitude of the constant-capacitance signal increase, resulting in an enhancement of analyte sensitivity of the EISCAP biosensor. In addition, the capability of the multicell arrangement with multi-enzyme covered EISCAPs for sequentially detecting multianalytes (penicillin and urea) utilizing the enzymes penicillinase and urease has been experimentally demonstrated and discussed.
KW  - Field-effect biosensor
KW  - Capacitive model
KW  - Enzyme coverage
KW  - Multianalyte detection
KW  - Penicillin
Y1  - 2024
U6  - http://dx.doi.org/10.1016/j.snb.2024.135530
SN  - 0925-4005 (Print)
SN  - 1873-3077 (Online)
N1  - Corresponding Author: Michael J. Schöning
VL  - 408
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Huck, Christina
A1  - Poghossian, Arshak
A1  - Bäcker, Matthias
A1  - Chaudhuri, S.
A1  - Zander, W.
A1  - Schubert, J.
A1  - Begoyan, V. K.
A1  - Buniatyan, V. V.
A1  - Wagner, P.
A1  - Schöning, Michael Josef
T1  - Capacitively coupled electrolyte-conductivity sensor based on high-k material of barium strontium titanate
JF  - Sensors and actuators. B: Chemical
Y1  - 2014
U6  - http://dx.doi.org/10.1016/j.snb.2014.02.103
SN  - 1873-3077 (E-Journal); 0925-4005 (Print)
IS  - 198
SP  - 102
EP  - 109
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Rodrigues, Raul T.
A1  - Morais, Paulo V.
A1  - Nordi, Cristina S. F.
A1  - Schöning, Michael Josef
A1  - Siqueira Jr., José R.
A1  - Caseli, Luciano
T1  - Carbon Nanotubes and Algal Polysaccharides To Enhance the Enzymatic Properties of Urease in Lipid Langmuir-Blodgett Films
JF  - Langmuir
N2  - Algal polysaccharides (extracellular polysaccharides) and carbon nanotubes (CNTs) were adsorbed on dioctadecyldimethylammonium bromide Langmuir monolayers to serve as a matrix for the incorporation of urease. The physicochemical properties of the supramolecular system as a monolayer at the air–water interface were investigated by surface pressure–area isotherms, surface potential–area isotherms, interfacial shear rheology, vibrational spectroscopy, and Brewster angle microscopy. The floating monolayers were transferred to hydrophilic solid supports, quartz, mica, or capacitive electrolyte–insulator–semiconductor (EIS) devices, through the Langmuir–Blodgett (LB) technique, forming mixed films, which were investigated by quartz crystal microbalance, fluorescence spectroscopy, and field emission gun scanning electron microscopy. The enzyme activity was studied with UV–vis spectroscopy, and the feasibility of the thin film as a urea sensor was essayed in an EIS sensor device. The presence of CNT in the enzyme–lipid LB film not only tuned the catalytic activity of urease but also helped to conserve its enzyme activity. Viability as a urease sensor was demonstrated with capacitance–voltage and constant capacitance measurements, exhibiting regular and distinctive output signals over all concentrations used in this work. These results are related to the synergism between the compounds on the active layer, leading to a surface morphology that allowed fast analyte diffusion owing to an adequate molecular accommodation, which also preserved the urease activity. This work demonstrates the feasibility of employing LB films composed of lipids, CNT, algal polysaccharides, and enzymes as EIS devices for biosensing applications.
Y1  - 2018
U6  - http://dx.doi.org/10.1021/acs.langmuir.7b04317
SN  - 1520-5827
VL  - 34
IS  - 9
SP  - 3082
EP  - 3093
PB  - ACS Publications
CY  - Washington, DC
ER  -