TY - CHAP A1 - Butenweg, Christoph A1 - Gellert, Christoph A1 - Reindl, Lukas T1 - Capacity design of masonry buildings under cyclic loading T2 - Seismic Risk : Earthquakes in North-Western Europe ; international colloquium ; Liège on 11 and 12 September 2008 / Belgian Seismic Group (BeSeiG). Ed.: T. Camlebeeck ... Y1 - 2008 SN - 978-2-87456-063-7 SP - 201 EP - 208 PB - Editions de l'Université de Liège CY - Liège ER - TY - CHAP A1 - Butenweg, Christoph A1 - Gellert, Christoph T1 - Displacement based design of masonry structures T2 - Proceedings of the 14th International Brick and Block Masonry Conference : (Incorporating the 8th Australasian Masonry Conference) : Sydney, Australia, 13.-20. February 2008 / ed. Mark Masia ... Y1 - 2008 SN - 978-19-2070-1-92-5 SP - 1 EP - 10 PB - University of Newcastle CY - Callaghan ER - TY - CHAP A1 - Meskouris, Konstantin A1 - Mistler, Michael A1 - Butenweg, Christoph T1 - Mauerwerksbauten unter Erdbebenbelastung T2 - Numerische Methoden zur Problemlösung im konstruktiven Bauwesen : 34. Aachener Baustofftag ; 02. Februar 2006 Y1 - 2006 PB - IBAC CY - Aachen ER - TY - CHAP A1 - Kuhlmann, Wolfram A1 - Butenweg, Christoph A1 - Lopez, Marijen A1 - Fernandez, Sebastian T1 - Seismic vulnerability assessment of the historic Aachen Cathedral T2 - Conference proceedings / 13th World Conference on Earthquake Engineering [Vancouver, British Columbia, Canada, August 1 - 6, 2004] / [hosted by CAEE/ACGP, Canadian Association for Earthquake Engineering] Y1 - 2004 SP - 1 EP - 14 PB - CAEE CY - Vancouver ER - TY - CHAP A1 - Kuhlmann, Wolfram A1 - Butenweg, Christoph A1 - Bettzieche, Volker A1 - Meskouris, Konstantin T1 - Experimentelle und numerische Untersuchungen zur baudynamischen Beurteilung von Talsperren des Ruhrverbandes T2 - 13. Deutsches Talsperrensymposium in Weimar Y1 - 2004 SP - 1 EP - 26 ER - TY - CHAP A1 - Butenweg, Christoph A1 - Bettzieche, Volker A1 - Kuhlmann, Wolfram A1 - Meskouris, Konstantin T1 - Die baudynamische Beurteilung von Talsperren am Beispiel der Fürwiggetalsperre T2 - Berichte der Fachtagung Baustatik - Baupraxis 9 am 14. und 15. März 2005 in Dresden / Institut für Statik und Dynamik der Tragwerke, TU Dresden, Deutschland Y1 - 2005 SN - 3-00-015456-6 SP - 73 EP - 84 PB - Inst. für Statik und Dynamik der Tragwerke CY - Dresden ER - TY - CHAP A1 - Meskouris, Konstantin A1 - Butenweg, Christoph A1 - Mistler, Michael A1 - Kuhlmann, Wolfram T1 - Seismic behaviour of historic masonry buildings T2 - 7th National Congress on Mechanics : Chania, Crete, June 24 - 26, 2004 ; proceedings / ed. A. Kounadis .... Y1 - 2004 SP - 47 EP - 49 PB - Hellenic Society for Theoretical and Applied Mechanics CY - Chania ER - TY - JOUR A1 - Butenweg, Christoph A1 - Gellert, Christoph A1 - Schlundt, Andreas T1 - Nichtlinearer Erdbebennachweis von Gebäuden aus Kalksandsteinmauerwerk nach DIN EN 1998 JF - Mauerwerk : European journal of masonry N2 - Die Erdbebensicherheit von Gebäuden aus Kalksandsteinmauerwerk ist aktuell nach DIN 4149 mit linearen Verfahren nachzuweisen. Dies führt in der praktischen Anwendung zu großen Problemen, da selbst traditionell übliche Grundrisse teilweise nicht mehr ohne zusätzliche Maßnahmen nachweisbar sind. Zur Lösung dieser Problematik wurden von der deutschen Mauerwerksindustrie auf nationaler und europäischer Ebene Forschungsprojekte initiiert, deren Ergebnisse in Form von statisch nichtlinearen Verfahren Eingang in den Nationalen Anhang zur DIN EN 1998-1 [12] gefunden haben. Mit den Verfahren wird die Nachweissituation zukünftig grundlegend verbessert, da mit diesen die Tragwerksreserven wesentlich besser ausgenutzt werden können. Im Folgenden wird die Anwendung der Verfahren am Beispiel einer Reihenhauszeile aus Kalksandsteinmauerwerk demonstriert. Der Nachweis der Reihenhäuser wurde im Rahmen einer Zustimmung im Einzelfall, die vom Bundesverband Kalksandsteinindustrie eV in Hannover koordiniert wurde, durch unabhängige Gutachter und die Bauaufsicht eingehend geprüft und für richtig befunden. Die Durchführung des Nachweises erfolgte auf Grundlage eines an der RWTH Aachen entwickelten neuen Nachweiskonzeptes. Die baupraktische Anwendbarkeit und einfache Nachvollziehbarkeit dieses Konzepts ist durch eine softwaretechnische Umsetzung sichergestellt. Y1 - 2010 U6 - https://doi.org/10.1002/dama.201000463 SN - 1432-3427 VL - 14 IS - 3 SP - 120 EP - 125 PB - Ernst & Sohn CY - Berlin ER - TY - JOUR A1 - Butenweg, Christoph A1 - Fäcke, Andreas A1 - Fehling, Ekkehard A1 - Gellert, Christoph A1 - Gierga, Michael A1 - Meyer, Udo A1 - Rütschlin, Andreas H. A1 - Stürz, Jochen T1 - Energieeffizient und erdbebensicher Bauen mit monolithischem Ziegelmauerwerk JF - Mauerwerk : European journal of masonry N2 - Moderne Bauwerke müssen heute eine hohe energetische Leistungsfähigkeit aufweisen und gleichzeitig alle einwirkenden Lasten sicher abtragen. Dies stellt insbesondere in Erdbebengebieten hohe Anforderungen an die verwendeten Baustoffe. Am baupraktischen Beispiel einer Doppelhaushälfte wird demonstriert, dass die Symbiose aus energieeffizientem und gleichzeitig erdbebensicherem Bauen in der höchsten deutschen Erdbebenzone mit monolithischem Ziegelmauerwerk gut realisierbar ist. Als Ziegelmauerwerk werden für die Außenwände wärmetechnisch optimierte Hochlochziegel verwendet, die sowohl die Anforderungen der Energieeinsparverordnung 2009 als auch die Anforderungen an Mauerwerkbaustoffe nach den aktuellen Erdbebennormen erfüllen. Der Erdbebennachweis der Doppelhaushälfte erfolgt mit einem nichtlinearen Nachweisverfahren, das für eine einfache praktische Anwendung programmtechnisch umgesetzt wurde. Für den Nachweis wurden aus zyklischen Schubwandversuchen ermittelte Last-Verformungskurven verwendet. Das gesamte in Deutschland noch nicht normativ geregelte Nachweiskonzept wurde im Rahmen einer Zustimmung im Einzelfall geprüft und genehmigt. Y1 - 2010 U6 - https://doi.org/10.1002/dama.201000456 SN - 1432-3427 VL - 14 IS - 1 SP - 3 EP - 9 PB - Ernst & Sohn CY - Berlin ER - TY - JOUR A1 - Edip, Kemal A1 - Garevski, Mihail A1 - Butenweg, Christoph A1 - Sesov, Vlatko A1 - Cvetanovska, Julijana A1 - Gjorgiev, Igor T1 - Numerical simulation of geotechnical problems by coupled finite and infinite elements JF - Journal of civil engineering and architecture Y1 - 2013 SN - 1934-7359 (E-Journal) VL - 7 IS - 1 SP - 68 EP - 77 PB - David Publishing CY - Libertyville ER - TY - JOUR A1 - Meskouris, Konstantin A1 - Butenweg, Christoph A1 - Gellert, Christoph T1 - Einfache Nachweise : einige Beispiele für die Anwendung des Bemessungsprogramms der RWTH Aachen für den Nachweis von Mauerwerksbauten in Erdbebengebieten JF - Deutsches Ingenieur-Blatt : Ingenieurwesen, Bautechnik, Umweltschutz ; Organ der deutschen Ingenieurkammern / Hrsg.: Bundes-Ingenieurkammer e.V. Y1 - 2009 SN - 0946-2422 N1 - Printausgabe in der Bibliothek Bayernallee vorhanden: 13 Z 842 IS - Heft 6 SP - 26 EP - 29 PB - Rauh Medien GmbH CY - Wandlitz ER - TY - JOUR A1 - Norda, Hannah A1 - Butenweg, Christoph T1 - Möglichkeiten und Grenzen der Anwendbarkeit statisch nichtlinearer Verfahren nach DIN EN 1998-1 JF - Bauingenieur : die richtungsweisende Zeitschrift im Bauingenieurswesen ; offizielle Zeitschrift der VDI-Gesellschaft Bautechnik. Beilage: D-A-CH-Mitteilungsblatt Y1 - 2011 SN - 1436-4867 (E-Journal); 0005-6650 (Print) N1 - Printausgabe in der Bibliothek Bayernallee vorhanden: 13 Z 049-2011 VL - Band 86 SP - S13 EP - S21 PB - VDI Fachmedien CY - Düsseldorf ER - TY - JOUR A1 - Meskouris, Konstantin A1 - Butenweg, Christoph A1 - Gellert, Christoph T1 - Iterativ verbessert : die RWTH Aachen entwickelt eine Software für einfache Nachweise von Mauerwerksbauten in Erdbebengebieten JF - Deutsches Ingenieur-Blatt : Ingenieurwesen, Bautechnik, Umweltschutz ; Organ der deutschen Ingenieurkammern / Hrsg.: Bundes-Ingenieurkammer e.V. Y1 - 2009 SN - 2365-192X N1 - Printausg. in der Bibliothek Bayernallee vorhanden: 13 Z 842 IS - Heft 5 SP - 31 EP - 36 PB - Rauh Medien GmbH CY - Wandlitz ER - TY - JOUR A1 - Butenweg, Christoph A1 - Gellert, Christoph A1 - Kranzler, Thomas T1 - Pseudo-dynamische Versuche an Reihenmittelhäusern – Vergleich mit aktuellen Berechnungsansätzen JF - Mauerwerk : European journal of masonry Y1 - 2008 U6 - https://doi.org/10.1002/dama.200800397 SN - 1437-1022 (E-Journal); 1432-3427 (Print) VL - Volume 12 IS - Issue 6 SP - 315 EP - 326 ER - TY - JOUR A1 - Gömmel, Andreas A1 - Butenweg, Christoph A1 - Bolender, Katrin A1 - Grunendahl, Arno T1 - A muscle controlled finite-element model of laryngeal abduction and adduction JF - Computer methods in biomechanics and biomedical engineering Y1 - 2007 SN - 1476-8259 (E-Journal); 1025-5842 (Print) VL - Volume 10 IS - Issue 5 SP - 377 EP - 388 ER - TY - JOUR A1 - Rochefort, E. de A1 - Verver, M. A1 - Grunendahl, A. A1 - Mooi, H. A1 - Butenweg, Christoph T1 - Detailed modelling of the lumbar spine for investigations of low back pain JF - SAE transactions : papers presented at Society and Section meetings / Society of Automotive Engineers Y1 - 2005 SN - 0096-736X VL - Volume 114 IS - Part 7 SP - 788 EP - 796 ER - TY - JOUR A1 - Kuhlmann, Wolfram A1 - Butenweg, Christoph A1 - Bettzieche, Volker T1 - Experimentelle und numerische Untersuchungen zur baudynamischen Beurteilung von Talsperren JF - Wasserwirtschaft : Hydrologie, Wasserbau, Hydromechanik, Gewässer, Ökologie, Boden Y1 - 2006 SN - 0043-0978 (E-Journal); 0043-0978 (Print) VL - Band 96 IS - Heft 5 SP - 10 EP - 16 ER - TY - JOUR A1 - Butenweg, Christoph A1 - Gellert, Christoph A1 - Meskouris, Konstantin T1 - Mauerwerkswände unter zyklischer Schubbeanspruchung JF - Mauerwerk : European journal of masonry Y1 - 2007 U6 - https://doi.org/10.1002/dama.200700356 SN - 1437-1022 (E-Journal); 1432-3427 (Print) VL - Volume 11 IS - Issue 6 SP - 356 EP - 362 ER - TY - JOUR A1 - Meskouris, Konstantin A1 - Butenweg, Christoph A1 - Renault, Philippe T1 - Mehrstufen-Konzept für mehr Erdbebensicherheit : ein Werkzeug für die Beurteilung der Erdbebengefährdung von Ingenieurbauwerken JF - Deutsches Ingenieurblatt Y1 - 2006 SN - 0946-2422 VL - Band 13 IS - Heft 6 SP - 18 EP - 26 ER - TY - JOUR A1 - Holtschoppen, Britta A1 - Butenweg, Christoph A1 - Meskouris, Konstantin T1 - Seismic design of non-structural components in industrial facilities JF - International journal of engineering under uncertainty Y1 - 2009 SN - 0975-4806 VL - Volume 1 SP - 1 EP - 13 ER - TY - CHAP A1 - Butenweg, Christoph A1 - Thierauf, G. ED - Papadrakakis, M. ED - Topping, B.H.V. T1 - Automatic design of reinforced concrete structures with parallel computing T2 - Innovative computational methods for structural mechanics N2 - A concept for the analysis and optimal design of reinforced concrete structures is described. It is based on a nonlinear optimization algorithm and a finite element program for linear and nonlinear analysis of structures. With the aim of minimal cost design a two stage optimization using efficient gradient algorithm is developed. The optimization problems on global (structural) and local (crosssectional) level are formulated. A parallelization concept for solving the two stage optimization problem in minimal time is presented. Examples are included to illustrate the practical use and the effectively of the parallelization in the area of engineering design. Y1 - 1999 SN - 1-874672-05-9 U6 - https://doi.org/10.4203/csets.1.14 SP - 305 EP - 318 PB - Saxe-Coburg Publication CY - Edinburgh ER - TY - BOOK A1 - Meskouris, Konstantin A1 - Renault, Philippe A1 - Butenweg, Christoph A1 - Hinzen, Klaus-G. A1 - Weber, Bernd T1 - Gefährdungsabschätzung von Brücken in Deutschland unter Erdbebenbelastung. [Bericht zum Forschungs- und Entwicklungsvorhaben FE 15.393/2003/FRB des Bundesministeriums für Verkehr, Bau und Stadtentwicklung.] (Forschung Straßenbau und Straßenverkehrstechnik ; 952) Y1 - 2007 SN - 978-3-86509-602-9 PB - Bundesministerium für Verkehr, Bau und Stadtentwicklung, Abt. Straßenbau, Straßenverkehr CY - Bonn ER - TY - CHAP A1 - Meskouris, Konstantin A1 - Butenweg, Christoph A1 - Kalker, Ines A1 - Mistler, Michael T1 - Numerical simulation of historic masonry buildings T2 - Antike Erdbeben im alpinen und zirkumalpinen Raum : Befunde und Probleme in archäologischer, historischer und seismologischer Sicht ; Beiträge des Interdisziplinären Workshops Schloss Hohenkammer, 14./15. Mai 2004 = Earthquakes in antiquity in the alpine and circum-alpine region / Gerhard H. Waldherr ; Anselm Smolka (Hrsg.) (Geographica Historica ; 24) Y1 - 2007 SN - 978-3-515-09030-8 ; 3-515-09030-4 SP - 171 EP - 189 PB - Franz Steiner Verlag CY - Stuttgart ER - TY - BOOK A1 - Meskouris, Konstantin A1 - Butenweg, Christoph A1 - Holler, Stefan A1 - Hake, Erwin T1 - Baustatik in Beispielen Y1 - 2012 SN - 978-3-642-23529-0 (Print) ; 978-3-642-23530-6 (E-Book) PB - Springer CY - Heidelberg ; Dordrecht ; London ; New York ET - 2., bearb. Aufl. ER - TY - RPRT A1 - Rosin, Julia A1 - Taddei, Francesca A1 - Schmitt, Timo A1 - Butenweg, Christoph T1 - Erdbebenschäden in der Emilia Romagna, Norditalien : DGEB-Erkundungsreise 1.6. - 4.6.2012 / C. Butenweg (Hrsg.) (DGEB-Publikation ; Nr. 15) Y1 - 2013 SN - 3-930108-11-9 PB - DGEB CY - Aachen ER - TY - CHAP A1 - Meskouris, Konstantin A1 - Butenweg, Christoph T1 - Erdbebensichere Auslegung von Bauwerken nach DIN 4149:2005 T2 - Betonkalender 2008: Konstruktiver Wasserbau, erdbebensicheres Bauen. Band 2 Y1 - 2008 SN - 978-3-433-01839-2 (Print) ; 978-3-433-01854-5 (E-Book) U6 - https://doi.org/10.1002/9783433600702.ch5 SP - 1 EP - 54 PB - Ernst & Sohn CY - Berlin ER - TY - CHAP A1 - Butenweg, Christoph A1 - Gellert, Christoph T1 - Berechnung und Bemessung von durch Erdbeben beanspruchten Mauerwerksbauten nach DIN 4149 (04.2005) T2 - Mauerwerksbau-Praxis / Schubert ; Schneider ; Schoch (Hrsg.) Y1 - 2007 SN - 3-9343-6938-3 ; 978-3-9343-6938-2 SP - 363 EP - 393 PB - Werner Verlag CY - Berlin ER - TY - BOOK A1 - Meskouris, Konstantin A1 - Hinzen, Klaus-Günter A1 - Butenweg, Christoph A1 - Mistler, Michael T1 - Bauwerke und Erdbeben : Grundlagen - Anwendung - Beispiele Y1 - 2007 SN - 3-8348-0146-1 ; 978-3-8348-0146-3 N1 - gedruckt in der Bereichsbibliothek Bayernallee unter der Signatur 11 XBM 41(2) vorhanden PB - Vieweg CY - Wiesbaden ET - 2., erweiterte und aktualisierte Auflage ER - TY - CHAP A1 - Marinkovic, Marko A1 - Butenweg, Christoph T1 - Seismic behaviour of RC frames with uncoupled masonry infills having two storeys or two bays T2 - Brick and Block Masonry - From Historical to Sustainable Masonry. Proceedings of the 17th International Brick/Block Masonry Conference N2 - Reinforced concrete (RC) structures with masonry infills are widely used for several types of buildings all over the world. However, it is well known that traditional masonry infills constructed with rigid contact to the surrounding RC frame performed rather poor in past earthquakes. Masonry infills showed severe in-plane damages and failed in many cases under out-of-plane seismic loading. As the undesired interactions between frames and infills changes the load transfer on building level, complete collapses of buildings were observed. A possible solution is uncoupling of masonry infills to the frame to reduce the infill contribution activated by the frame deformation under horizontal loading. The paper presents numerical simulations on RC frames equipped with the innovative decoupling system INODIS. The system was developed within the European project INSYSME and allows an effective uncoupling of frame and infill. The simulations are carried out with a micro-modelling approach, which is able to predict the complex nonlinear behaviour resulting from the different materials and their interaction. Each brick is modelled individually and connected taking into account nonlinearity of a brick mortar interface. The calibration of the model is based on small specimen tests and experimental results for one bay one storey frame are used for the validation. The validated model is further used for parametric studies on two storey and two bay infilled frames. The response and change of the structural stiffness are analysed and compared to the traditionally infilled frame. The results confirm the effectiveness of the INODIS system with less damage and relatively low contribution of the infill at high drift levels. In contrast to the uncoupled system configurations, traditionally infilled frames experienced brittle failure at rather low drift levels. Y1 - 2020 U6 - https://doi.org/10.1201/9781003098508-72 N1 - 17th International Brick/Block Masonry Conference (17thIB2MaC 2020), July 5-8, 2020, Kraków, Poland SP - 1 EP - 7 PB - CRC Press CY - London ER - TY - CHAP A1 - Michel, Philipp A1 - Rosin, Julia A1 - Butenweg, Christoph A1 - Klinkel, Sven T1 - Soil-dependent earthquake spectra in the analysis of liquid-storage-tanks on compliant soil T2 - Seismic design of industrial facilities 2020 N2 - A further development of the Added-Mass-Method allows the combined representation of the effects of both soil-structure-interaction and fluid-structure interaction on a liquid-filled-tank in one model. This results in a practical method for describing the dynamic fluid pressure on the tank shell during joint movement. The fluid pressure is calculated on the basis of the tank's eigenform and the earthquake acceleration and represented by additional masses on the shell. The bearing on compliant ground is represented by replacement springs, which are calculated dependent on the local soil composition. The influence of the shear modulus of the compliant soil is clearly visible in the pressure curves and the stress distribution in the shell. The acceleration spectra are also dependent on soil stiffness. According to Eurocode-8 the acceleration spectra are determined for fixed soil-classes, instead of calculating the accelerations for each site in direct dependence on the soil composition. This leads to unrealistic sudden changes in the system's response. Therefore, earthquake spectra are calculated for different soil models in direct dependence of the shear modulus. Thus, both the acceleration spectra and the replacement springs match the soil composition. This enables a reasonable and consistent calculation of the system response for the actual conditions at each site. Y1 - 2020 SN - 978-3-86359-729-0 N1 - 2nd International Conference on Seismic Design of Industrial Facilities (Aachen, Germany, March 4-5, 2020) SP - 245 EP - 254 PB - Apprimus Verlag CY - Aachen ER - TY - CHAP A1 - Markinkovic, Marko A1 - Butenweg, Christoph A1 - Pavese, A. A1 - Lanese, I. A1 - Hoffmeister, B. A1 - Pinkawa, M. A1 - Vulcu, C. A1 - Bursi, O. A1 - Nardin, C. A1 - Paolacci, F. A1 - Quinci, G. A1 - Fragiadakis, M. A1 - Weber, F. A1 - Huber, P. A1 - Renault, P. A1 - Gündel, M. A1 - Dyke, S. A1 - Ciucci, M. A1 - Marino, A. T1 - Investigation of the seismic behaviour of structural and nonstructural components in industrial facilities by means of shaking table tests T2 - Seismic design of industrial facilities 2020 Y1 - 2020 SN - 978-3-86359-729-0 N1 - 2nd International Conference on Seismic Design of Industrial Facilities (Aachen, Germany, March 4-5, 2020) SP - 159 EP - 172 PB - Apprimus Verlag CY - Aachen ER - TY - CHAP A1 - Cacciatore, Pamela A1 - Butenweg, Christoph T1 - Seismic safety of cylindrical granular material steel silos under seismic loading T2 - Seismic design of industrial facilities 2020 Y1 - 2020 SN - 978-3-86359-729-0 N1 - 2nd International Conference on Seismic Design of Industrial Facilities (Aachen, Germany, March 4-5, 2020) SP - 231 EP - 244 PB - Apprimus Verlag CY - Aachen ER - TY - CHAP A1 - Butenweg, Christoph A1 - Ebenau, C. T1 - Entwicklung eines objekt-orientierten FE-Programms T2 - Forum Bauinformatik - Junge Wissenschaftler forschen, Cottbus '96 Y1 - 1996 SN - 978-3-18-313504-2 N1 - Fortschritt-Berichte VDI : Reihe 4, Bauingenieurwesen, Band 135 SP - 60 EP - 65 PB - VDI-Verlag CY - Düsseldorf ER - TY - CHAP A1 - Akimbekov, Nuraly S. A1 - Digel, Ilya A1 - Sherelkhan, Dinara K. A1 - Razzaque, Mohammed S. T1 - Vitamin D and Phosphate Interactions in Health and Disease T2 - Phosphate Metabolism N2 - Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis, maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as calcitriol (1,25(OH)2D), not only increases intestinal calcium and phosphate absorption but also facilitates their renal reabsorption, leading to elevated serum calcium and phosphate levels. The interaction of 1,25(OH)2D with its receptor (VDR) increases the efficiency of intestinal absorption of calcium to 30–40% and phosphate to nearly 80%. Serum phosphate levels can also influence 1,25 (OH)2D and fibroblast growth factor 23 (FGF23) levels, i.e., higher phosphate concentrations suppress vitamin D activation and stimulate parathyroid hormone (PTH) release, while a high FGF23 serum level leads to reduced vitamin D synthesis. In the vitamin D-deficient state, the intestinal calcium absorption decreases and the secretion of PTH increases, which in turn causes the stimulation of 1,25(OH)2D production, resulting in excessive urinary phosphate loss. Maintenance of phosphate homeostasis is essential as hyperphosphatemia is a risk factor of cardiovascular calcification, chronic kidney diseases (CKD), and premature aging, while hypophosphatemia is usually associated with rickets and osteomalacia. This chapter elaborates on the possible interactions between vitamin D and phosphate in health and disease. KW - Vitamin D KW - PTH KW - Phosphate KW - FGF23 KW - Klotho Y1 - 2022 SN - 978-3-030-91621-3 U6 - https://doi.org/10.1007/978-3-030-91623-7_5 SP - 37 EP - 46 PB - Springer CY - Cham ER - TY - CHAP A1 - Dachwald, Bernd T1 - Global optimization of low-thrust space missions using evolutionary neurocontrol T2 - Proceedings of the international workshop on global optimization N2 - Low-thrust space propulsion systems enable flexible high-energy deep space missions, but the design and optimization of the interplanetary transfer trajectory is usually difficult. It involves much experience and expert knowledge because the convergence behavior of traditional local trajectory optimization methods depends strongly on an adequate initial guess. Within this extended abstract, evolutionary neurocontrol, a method that fuses artificial neural networks and evolutionary algorithms, is proposed as a smart global method for low-thrust trajectory optimization. It does not require an initial guess. The implementation of evolutionary neurocontrol is detailed and its performance is shown for an exemplary mission. KW - Evolutionary Neurocontrol KW - Spacecraft Trajectory Optimization KW - Low-Thrust Propulsion Y1 - 2005 SP - 85 EP - 90 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Kahle, Ralph A1 - Wie, Bong T1 - Solar Sailing Kinetic Energy Impactor (KEI) Mission Design Tradeoffs for Impacting and Deflecting Asteroid 99942 Apophis JF - AIAA Guidance, Navigation, and Control Conference & Exhibit - AIAA Atmospheric Flight Mechanics Conference & Exhibit - AIAA Modeling and Simulation Technologies Conference & Exhibit - AIAA/AAS Astrodynamics Specialist Conference & Exhibit : [21 - 24 August 2006, Keystone, Colorado ; papers]. - (AIAA meeting papers on disc ; [11.]2006,19-20 ) Y1 - 2006 SN - 1-56347-802-1 N1 - American Institute of Aeronautics and Astronautics ; American Astronautical Society ; AIAA/AAS Astrodynamics Specialist Conference & Exhibit <2006, Keystone, Colo.> ; AIAA paper number: AIAA-2006-6178 SP - 1 EP - 20 PB - American Institute of Aeronautics and Astronautics CY - Reston, Va. ER - TY - JOUR A1 - Saffe, P. A1 - Lodewiks, J. A1 - Haas, H.-J. A1 - Feigel, H.-J. A1 - Ulrich, H. A1 - Mauer, J. A1 - Ortwig, H. A1 - Dahmann, Peter A1 - Rotthäuser, S. A1 - Tao, J. A1 - Ohlischläger, O. A1 - Scholz, D. A1 - Bergmann, M. A1 - Anders, P. T1 - Neues von ASB Antreiben – Steuern – Bewegen JF - Ölhydraulik und Pneumatik. Vol. 33 (1989), H. 7 Y1 - 1989 SN - 0341-2660 SP - 550 EP - 572 ER - TY - CHAP A1 - Alexopoulos, Spiros T1 - Biomass technology and bio-fuels: Heating/cooling and power T2 - Renewable energy systems : theory, innovations, and intelligent applications / eds.: Socrates Kaplanis and Eleni Kaplani Y1 - 2013 SN - 9781624177415 SP - 501 EP - 523 PB - Nova Science Publ. CY - Hauppauge, NY ER - TY - CHAP A1 - Schartner, Karl-Heinz A1 - Loeb, H. W. A1 - Dachwald, Bernd A1 - Ohndorf, Andreas T1 - Perspectives of electric propulsion for outer planetary and deep space missions T2 - European Planetary Science Congress 2009 N2 - Solar-electric propulsion (SEP) is superior with respect to payload capacity, flight time and flexible launch window to the conventional interplanetary transfer method using chemical propulsion combined with gravity assists. This fact results from the large exhaust velocities of electric low–thrust propulsion and is favourable also for missions to the giant planets, Kuiper-belt objects and even for a heliopause probe (IHP) as shown in three studies by the authors funded by DLR. They dealt with a lander for Europa and a sample return mission from a mainbelt asteroid [1], with the TANDEM mission [2]; the third recent one investigates electric propulsion for the transfer to the edge of the solar system. All studies are based on triple-junction solar arrays, on rf-ion thrusters of the qualified RIT-22 type and they use the intelligent trajectory optimization program InTrance [3]. Y1 - 2009 N1 - European Planetary Science Congress 2009, 13-18 September, Potsdam, Germany SP - 416 EP - 416 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Seboldt, Wolfgang A1 - Macdonald, Malcolm A1 - Mengali, Giovanni A1 - Quatra, Alessandro A. A1 - McInnes, Colin R. A1 - Rios-Reyes, Leonel A1 - Scheerers, Daniel J. A1 - Wie, Bong A1 - Görlich, Marianne A1 - Lura, Franz A1 - Diedrich, Benjamin A1 - Baturkin, Volodymyr A1 - Coverstone, Victoria L. A1 - Leipold, Manfred A1 - Garbe, Gregory P. T1 - Potential Solar Sail Degradation Effects on Trajectory and Attitude Control JF - AIAA Guidance, Navigation and Control Conference and Exhibit - AIAA Modeling and Simulation Technologies Conference and Exhibit - AIAA Atmospheric Flight Mechanics Conference and Exhibit : [San Francisco, California, 15 - 18 August 2005 ; papers]. - (AIAA meeting papers on disc ; [10.]2005,16-17) Y1 - 2005 SN - 1-56347-765-3 N1 - American Institute of Aeronautics and Astronautics ; AIAA Guidance, Navigation, and Control Conference and Exhibit <2005, San Francisco, Calif.> ; AIAA paper number: AIAA-2006-6172 Link "https://arc.aiaa.org/doi/book/10.2514/MGNC05" am 15.07.2022 nachgetragen Behr PB - American Institute of Aeronautics and Astronautics CY - Reston, Va. ER - TY - BOOK A1 - Bleninger, T. A1 - Brenda, M. A1 - Bung, Daniel Bernhard A1 - Hengl, M. A1 - Schmid, B.H. A1 - Schneider, E. A1 - Sonnenburg, A. A1 - Stoschek, O. T1 - DWA-Regelwerk M 544-2 : Merkblatt: Ausbreitungsprobleme von Einleitungen - Prozesse, Methoden und Modelle - Teil 2: Mehrdimensionale Modelle Y1 - 2016 SN - 978-3-88721-281-0 CY - Hennef ER - TY - JOUR A1 - Zerlin, Kay A1 - Digel, Ilya A1 - Stadler, Andreas M. A1 - Büldt, Georg A1 - Zaccai, Guiseppe A1 - Artmann, Gerhard T1 - Dynamics and interactions of hemoglobin in human red blood cells and concentrated hemoglobin solutions JF - Regenerative medicine. 2 (2007), H. 5 Y1 - 2007 SN - 1746-0751 N1 - Proceedings of the 3rd World Congress on Regenerative Medicine. October 18-20, 2007. Leipzig, Germany SP - 573 EP - 573 ER - TY - CHAP A1 - Wolf, Martin R. A1 - Schlick, Christopher A1 - Herbst, D. A1 - Springer, J. ED - Uellner, Stefan T1 - Einflussfaktoren auf den Erfolg von Telekooperation in großen Unternehmen T2 - Computer Supported Cooperative Work (CSCW) in großen Unternehmungen : Tagungsband zum Workshop der GI-Fachgruppe 5.5.1 "CSCW in Organisationen" und dem Technologiezentrum Darmstadt der Deutschen Telekom AG vom 09. - 10. Mai 1996 Y1 - 1996 SP - 1 EP - 12 PB - Dt. Telekom CY - Darmstadt ER - TY - JOUR A1 - Akimbekov, Nuraly S. A1 - Digel, Ilya A1 - Sherelkhan, Dinara K. A1 - Lutfor, Afzalunnessa B. A1 - Razzaque, Mohammed S. T1 - Vitamin D and the Host-Gut Microbiome: A Brief Overview JF - Acta Histochemica et Cytochemica N2 - There is a growing body of evidence for the effects of vitamin D on intestinal host-microbiome interactions related to gut dysbiosis and bowel inflammation. This brief review highlights the potential links between vitamin D and gut health, emphasizing the role of vitamin D in microbiological and immunological mechanisms of inflammatory bowel diseases. A comprehensive literature search was carried out in PubMed and Google Scholar using combinations of keywords “vitamin D,” “intestines,” “gut microflora,” “bowel inflammation”. Only articles published in English and related to the study topic are included in the review. We discuss how vitamin D (a) modulates intestinal microbiome function, (b) controls antimicrobial peptide expression, and (c) has a protective effect on epithelial barriers in the gut mucosa. Vitamin D and its nuclear receptor (VDR) regulate intestinal barrier integrity, and control innate and adaptive immunity in the gut. Metabolites from the gut microbiota may also regulate expression of VDR, while vitamin D may influence the gut microbiota and exert anti-inflammatory and immune-modulating effects. The underlying mechanism of vitamin D in the pathogenesis of bowel diseases is not fully understood, but maintaining an optimal vitamin D status appears to be beneficial for gut health. Future studies will shed light on the molecular mechanisms through which vitamin D and VDR interactions affect intestinal mucosal immunity, pathogen invasion, symbiont colonization, and antimicrobial peptide expression. Y1 - 2020 U6 - https://doi.org/10.1267/ahc.20011 SN - 1347-5800 VL - 53 IS - 3 SP - 33 EP - 42 PB - Japan Society of Histochemistry and Cytochemistry CY - Osaka ER - TY - CHAP A1 - Digel, Ilya A1 - Mansurov, Zulkhair A1 - Biisenbaev, Makhmut A1 - Savitskaya, Irina A1 - Kistaubaeva, Aida A1 - Akimbekov, Nuraly S. A1 - Zhubanova, Azhar ED - Hu, Ning T1 - Heterogeneous Composites on the Basis of Microbial Cells and Nanostructured Carbonized Sorbents T2 - Composites and Their Applications N2 - The fact that microorganisms prefer to grow on liquid/solid phase surfaces rather than in the surrounding aqueous phase was noticed long time ago [1]. Virtually any surface – animal, mineral, or vegetable – is a subject for microbial colonization and subsequent biofilm formation. It would be adequate to name just a few notorious examples on microbial colonization of contact lenses, ship hulls, petroleum pipelines, rocks in streams and all kinds of biomedical implants. The propensity of microorganisms to become surface-bound is so profound and ubiquitous that it vindicates the advantages for attached forms over their free-ranging counterparts [2]. Indeed, from ecological and evolutionary standpoints, for many microorganisms the surface-bound state means dwelling in nutritionally favorable, non-hostile environments [3]. Therefore, in most of natural and artificial ecosystems surface-associated microorganisms vastly outnumber organisms in suspension and often organize into complex communities with features that differ dramatically from those of free cells [4]. Y1 - 2012 SN - 978-953-51-0706-4 U6 - https://doi.org/10.5772/47796 SP - 249 EP - 272 PB - Intech CY - London ER - TY - CHAP A1 - Bertsch, Timo A1 - Meinecke, Matthias A1 - Wolf, Martin R. A1 - Schmunk, Karina T1 - Smart-Living-Services nur gegen Daten? Process-Mining als Möglichkeit zur Steigerung der Akzeptanz! T2 - Angewandte Forschung in der Wirtschaftsinformatik 2019 : Tagungsband zur 32. AKWI-Jahrestagung / hrsg. von Martin R. Wolf, Thomas Barton, Frank Herrmann, Vera G. Meister, Christian Müller, Christian Seel N2 - Seit Jahren etablieren sich Technologien in unserem Alltag, die mit Hilfe von smarten Komponenten neue Services und Vernetzungsmöglichkeiten schaffen. Dieses Paper beschreibt die Ergebnisse einer Studie, die die Akzeptanz von IoT-gestützten, smarten Services im privaten Umfeld untersucht. Dabei wird eine zentrale Datenverarbeitung mit automatisierter Erstellung smarter Services der dezentralen Datenverarbeitung mit manueller Serviceerstellung in sieben Kategorien gegenübergestellt. Die Auswertung der Studie legt die Forschungsfrage nahe, ob das Nutzerverhalten im Kontext Smart Living nicht auch mit einem dezentralen Lösungsansatz, und somit unabhängig von großen Unternehmen, analysiert werden kann. Hierfür wird im zweiten Teil des Papers die Anwendbarkeit von Process-Mining im Bereich Smart Living untersucht und prototypisch getestet. Y1 - 2019 SN - 978-3-944330-62-4 SP - 216 EP - 226 PB - mana-Buch CY - Heide ER - TY - JOUR A1 - Peloni, Alessandro A1 - Ceriotti, Matteo A1 - Dachwald, Bernd T1 - Solar-sail trajectory design for a multiple near-earth-asteroid rendezvous mission JF - Journal of Guidance, Control, and Dynamics N2 - The scientific interest for near-Earth asteroids as well as the interest in potentially hazardous asteroids from the perspective of planetary defense led the space community to focus on near-Earth asteroid mission studies. A multiple near-Earth asteroid rendezvous mission with close-up observations of several objects can help to improve the characterization of these asteroids. This work explores the design of a solar-sail spacecraft for such a mission, focusing on the search of possible sequences of encounters and the trajectory optimization. This is done in two sequential steps: a sequence search by means of a simplified trajectory model and a set of heuristic rules based on astrodynamics, and a subsequent optimization phase. A shape-based approach for solar sailing has been developed and is used for the first phase. The effectiveness of the proposed approach is demonstrated through a fully optimized multiple near-Earth asteroid rendezvous mission. The results show that it is possible to visit five near-Earth asteroids within 10 years with near-term solar-sail technology. Y1 - 2016 U6 - https://doi.org/10.2514/1.G000470 SN - 0731-5090 VL - 39 IS - 12 SP - 2712 EP - 2724 PB - AIAA CY - Reston, Va. ER - TY - CHAP A1 - Digel, Ilya A1 - Sadykov, R. A1 - Temiz Artmann, Aysegül A1 - Artmann, Gerhard T1 - Changes in intestinal microflora in rats induced by oral exposure to low lead (II) concentrations T2 - Lead Exposure and Poisoning: Clinical Symptoms, Medical Management and Preventive Strategies Y1 - 2015 SN - 9781634826990 SP - 75 EP - 99 PB - Nova Science Publ. ER - TY - JOUR A1 - Schroeter, Rebecca A1 - Hoffmann, Tamara A1 - Voigt, Birgit A1 - Meyer, Hanna A1 - Bleisteiner, Monika A1 - Muntel, Jan A1 - Jürgen, Britta A1 - Albrecht, Dirk A1 - Becher, Dörte A1 - Lalk, Michael A1 - Evers, Stefan A1 - Bongaerts, Johannes A1 - Maurer, Karl-Heinz A1 - Putzer, Harald A1 - Hecker, Michael A1 - Schweder, Thomas A1 - Bremer, Erhard T1 - Stress responses of the industrial workhorse Bacillus licheniformis to osmotic challenges JF - PLoS ONE N2 - The Gram-positive endospore-forming bacterium Bacillus licheniformis can be found widely in nature and it is exploited in industrial processes for the manufacturing of antibiotics, specialty chemicals, and enzymes. Both in its varied natural habitats and in industrial settings, B. licheniformis cells will be exposed to increases in the external osmolarity, conditions that trigger water efflux, impair turgor, cause the cessation of growth, and negatively affect the productivity of cell factories in biotechnological processes. We have taken here both systems-wide and targeted physiological approaches to unravel the core of the osmostress responses of B. licheniformis. Cells were suddenly subjected to an osmotic upshift of considerable magnitude (with 1 M NaCl), and their transcriptional profile was then recorded in a time-resolved fashion on a genome-wide scale. A bioinformatics cluster analysis was used to group the osmotically up-regulated genes into categories that are functionally associated with the synthesis and import of osmostress-relieving compounds (compatible solutes), the SigB-controlled general stress response, and genes whose functional annotation suggests that salt stress triggers secondary oxidative stress responses in B. licheniformis. The data set focusing on the transcriptional profile of B. licheniformis was enriched by proteomics aimed at identifying those proteins that were accumulated by the cells through increased biosynthesis in response to osmotic stress. Furthermore, these global approaches were augmented by a set of experiments that addressed the synthesis of the compatible solutes proline and glycine betaine and assessed the growth-enhancing effects of various osmoprotectants. Combined, our data provide a blueprint of the cellular adjustment processes of B. licheniformis to both sudden and sustained osmotic stress. Y1 - 2014 U6 - https://doi.org/10.1371/journal.pone.0080956 SN - 1932-6203 VL - 8 IS - 11 PB - PLOS CY - San Francisco ER - TY - JOUR A1 - Pogorelova, Natalia A1 - Rogachev, Evgeniy A1 - Akimbekov, Nuraly S. A1 - Digel, Ilya T1 - Effect of dehydration method on the micro- and nanomorphological properties of bacterial cellulose produced by Medusomyces gisevii on different substrates JF - Journal of materials science N2 - Many important properties of bacterial cellulose (BC), such as moisture absorption capacity, elasticity and tensile strength, largely depend on its structure. This paper presents a study on the effect of the drying method on BC films produced by Medusomyces gisevii using two different procedures: room temperature drying (RT, (24 ± 2 °C, humidity 65 ± 1%, dried until a constant weight was reached) and freeze-drying (FD, treated at − 75 °C for 48 h). BC was synthesized using one of two different carbon sources—either glucose or sucrose. Structural differences in the obtained BC films were evaluated using atomic force microscopy (AFM), scanning electron microscopy (SEM), and X-ray diffraction. Macroscopically, the RT samples appeared semi-transparent and smooth, whereas the FD group exhibited an opaque white color and sponge-like structure. SEM examination showed denser packing of fibrils in FD samples while RT-samples displayed smaller average fiber diameter, lower surface roughness and less porosity. AFM confirmed the SEM observations and showed that the FD material exhibited a more branched structure and a higher surface roughness. The samples cultivated in a glucose-containing nutrient medium, generally displayed a straight and ordered shape of fibrils compared to the sucrose-derived BC, characterized by a rougher and wavier structure. The BC films dried under different conditions showed distinctly different crystallinity degrees, whereas the carbon source in the culture medium was found to have a relatively small effect on the BC crystallinity. Y1 - 2024 U6 - https://doi.org/10.1007/s10853-024-09596-3 SN - 1573-4803 (Online) SN - 0022-2461 (Print) N1 - Corresponding author: Ilya Digel VL - 2024 PB - Springer Science + Business Media CY - Dordrecht ER -