TY  - JOUR
A1  - Iding, Hans
A1  - Dünnwald, Thomas
A1  - Greiner, Lasse
A1  - Liese, Andreas
A1  - Müller, Michael
A1  - Siegert, Petra
A1  - Grötzinger, Joachim
A1  - Demir, Ayhan S.
A1  - Pohl, Martina
T1  - Benzoylformate Decarboxylase from Pseudomonas putida as Stable Catalyst for the Synthesis of Chiral 2-Hydroxy Ketones
JF  - Chemistry - a European journal
Y1  - 2000
SN  - 1521-3765 (E-Journal); 0947-6539 (Print)
VL  - Vol. 6
IS  - Iss. 8
SP  - 1483
EP  - 1495
ER  - 
TY  - JOUR
A1  - Whitehead, Mark
A1  - Öhlschläger, Peter
A1  - Almajhdi, Fahad N.
A1  - Alloza, Leonor
A1  - Marzábal, Pablo
A1  - Meyers, Ann E.
A1  - Hitzeroth, Inga I.
A1  - Rybicki, Edward P.
T1  - Human papillomavirus (HPV) type 16 E7 protein bodies cause tumour regression in mice
JF  - BMC cancer
Y1  - 2014
U6  - https://doi.org/10.1186/1471-2407-14-367
SN  - 1471-2407
IS  - 14:367
SP  - 1
EP  - 15
PB  - BioMed Central
CY  - London
ER  - 
TY  - PAT
A1  - Siegert, Petra
A1  - Merkel, Marion
A1  - Hellmuth, Hendrik
A1  - O'Connell, Timothy
A1  - Maurer, Karl-Heinz
T1  - Stabilisierte flüssige enzymhaltige Tensidzubereitung (Einsatz einer das hydrolytische Enzym stabilisierende Komponente, die ein Monosaccharidglycerat umfasst) [Offenlegungsschrift]
T1  - Stabilized liquid enzyme-containing surfactant preparation (using a component which comprises a monosaccharide glycerate and which stabilizes the hydrolytic enzyme) [Europäische Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2012
SP  - 1
EP  - 17
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - PAT
A1  - Siegert, Petra
A1  - Merkel, Marion
A1  - Kluin, Cornelia
A1  - Maurer, Karl-Heinz
A1  - O'Connell, Timothy
A1  - Wieland, Susanne
A1  - Hellmuth, Hendrik
T1  - Neue Proteasen und diese enthaltende Mittel [Offenlegungsschrift]
T1  - Novel proteases and compositions comprising them [Europäische Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2011
SP  - 1
EP  - 21
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - PAT
A1  - Siegert, Petra
A1  - Schwaneberg, Ulrich
A1  - Martinez Moya, Ronny
A1  - Merkel, Marion
A1  - Spitz, Astrid
A1  - Wieland, Susanne
A1  - Hellmuth, Hendrik
A1  - Maurer, Karl-Heinz
T1  - Leistungsverbesserte Proteasevariante [Offenlegungsschrift]
T1  - Performance-enhanced protease variant [Europäische Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2012
SP  - 1
EP  - 29
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - PAT
A1  - Wieland, Susanne
A1  - Siegert, Petra
A1  - Spitz, Astrid
A1  - Maurer, Karl-Heinz
A1  - O'Connell, Timothy
A1  - Prüser, Inken
A1  - Schiedel, Marc-Steffen
A1  - Eiting, Thomas
A1  - Sendor-Müller, Dorota
A1  - Bastigkeit, Thorsten
A1  - Benda, Konstantin
A1  - Müller, Sven
T1  - Lagerstabiles flüssiges Wasch- oder Reinigungsmittel enthaltend Proteasen [Offenlegungsschrift]
T1  - Storage-stable liquid washing or cleaning agent containing proteases [Europäische Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2011
SP  - 1
EP  - 25
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - PAT
A1  - Siegert, Petra
A1  - Mussmann, Nina
A1  - O'Connell, Timothy
A1  - Maurer, Karl-Heinz
T1  - Neue Proteasen und Mittel enthaltend diese Proteasen [Offenlegungsschrift]
T1  - Novel proteases and means containing said proteases [Internationale Patentanmeldung]
Y1  - 2010
SP  - 1
EP  - 30
PB  - Deutsches Patent- und Markenamt / WIPO
CY  - München / Genf
ER  - 
TY  - PAT
A1  - Siegert, Petra
A1  - Baumstark, Rebecca
A1  - Kluin, Cornelia
A1  - O'Connell, Timothy
A1  - Maurer, Karl-Heinz
A1  - Hellmuth, Hendrik
T1  - Neue Proteasen und Mittel enthaltend diese Proteasen [Offenlegungsschrift]
Y1  - 2010
SP  - 1
EP  - 30
PB  - Deutsches Patent- und Markenamt
CY  - München
ER  - 
TY  - PAT
A1  - Siegert, Petra
A1  - Spitz, Astrid
A1  - Maurer, Karl-Heinz
T1  - Neue Proteasen und Mittel enthaltend diese Proteasen [Offenlegungsschrift]
T1  - Novel proteases and compositions comprising these proteases [Internationale Patentanmeldung]
Y1  - 2010
SP  - 1
EP  - 31
PB  - Deutsches Patentamt / WIPO
CY  - München / Genf
ER  - 
TY  - PAT
A1  - Siegert, Petra
A1  - Spitz, Astrid
A1  - Maurer, Karl-Heinz
T1  - Wasch- und Reinigungsmittel enthaltend Proteasen aus Bacillus pumilus [Offenlegungsschrift]
T1  - Detergents and cleaning agents containing proteases from bacillus pumilus [Europäische Patentschrift / Internationale Patentanmeldung]
Y1  - 2010
SP  - 1
EP  - 20
PB  - Deutsches Patentamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - PAT
A1  - O'Connell, Timothy
A1  - Siegert, Petra
A1  - Evers, Stefan
A1  - Bongaerts, Johannes
A1  - Weber, Thomas
A1  - Maurer, Karl-Heinz
A1  - Bessler, Cornelius
T1  - Wasch- oder Reinigungsmittel mit gesteigerter Waschkraft [Offenlegungsschrift]
T1  - Method from improving the cleaning action of a detergent of cleaning agent [US Patentanmeldung]
Y1  - 2010
SP  - 1
EP  - 34
PB  - Deutsches Patentamt
CY  - München
ER  - 
TY  - JOUR
A1  - Iding, Hans
A1  - Siegert, Petra
A1  - Mesch, K.
A1  - Pohl, Martina
T1  - Application of α-keto acid decarboxylases in biotransformations
JF  - Biochimica et biophysica acta (BBA) - Protein structure and molecular enzymology
Y1  - 1998
SN  - 1879-2588 (E-Journal); 0167-4838 (Print)
VL  - Vol. 1385
IS  - Iss. 2
SP  - 307
EP  - 322
ER  - 
TY  - JOUR
A1  - Pohl, Martina
A1  - Siegert, Petra
A1  - Mesch, K.
A1  - Bruhn, H.
A1  - Grötzinger, Joachim
T1  - Active site mutants of pyruvate decarboxylase from Zymomonas mobilis : a site-directed mutagenesis study of L112, I472, I476, E473 and N482
JF  - European journal of biochemistry
Y1  - 1998
SN  - 1432-1033 (E-Journal); 1742-4658 (E-Journal); 0014-2956 (Print); 1742-464X (Print)
VL  - Vol. 257
IS  - Iss. 3
SP  - 538
EP  - 546
ER  - 
TY  - PAT
A1  - Siegert, Petra
A1  - Evers, Stefan
A1  - Marion, Merkel
A1  - Mussmann, Nina
A1  - Hellmuth, Hendrik
A1  - O'Connell, Timothy
A1  - Maurer, Karl-Heinz
A1  - Schwaneberg, Ulrich
A1  - Martinez, Ronny
A1  - Jakob, Felix
T1  - Verfahren zur Anpassung eines hydrolytischen Enzyms an eine das hydrolytische Enzym stabilisierende Komponente [Offenlegungsschrift]
T1  - Method for adapting a hydrolytic enzyme to a component that stabilizes the hydrolytic enzyme [Europäische Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2013
SP  - 1
EP  - 27
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - PAT
A1  - Maurer, Karl-Heinz
A1  - O'Connell, Timothy
A1  - Siegert, Petra
A1  - Weber, Thomas
A1  - Tondera, Susanne
A1  - Hellmuth, Hendrik
T1  - Flüssige Tensidzubereitung enthaltend Lipase und Phosphonat [Offenlegungsschrift]
T1  - Liquid surfactant preparation containing lipase and phosphonate [Europäische Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2012
SP  - 1
EP  - 22
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - PAT
A1  - Siegert, Petra
A1  - Merkel, Marion
A1  - Hellmuth, Hendrik
A1  - O'Connell, Timothy
A1  - Maurer, Karl-Heinz
T1  - Stabilisierte flüssige enzymhaltige Tensidzubereitung (Einsatz einer das hydrolytische Enzym stabilisierenden Komponente, die eine Phenylalkyldicarbonsäure umfasst) [Offenlegungsschrift]
T1  - Stabilized liquid tenside preparation comprising enzymes (using a component that stabilizes the hydrolytic enzyme and includes a phenylalkyldicarboxylic acid) [Europäische Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2012
SP  - 1
EP  - 15
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - PAT
A1  - Siegert, Petra
A1  - Merkel, Marion
A1  - Hellmuth, Hendrik
A1  - O'Connell, Timothy
A1  - Maurer, Karl-Heinz
T1  - Stabilisierte flüssige enzymhaltige Tensidzubereitung (durch den Einsatz einer das hydrolytische Enzym stabilisierende Komponente, die eine mehrfach substituierte Benzolcarbonsäure umfasst, die an mindestens zwei Kohlenstoffatomen des Benzolrestes eine Carboxylgruppe aufweist) [Offenlegungsschrift]
T1  - Stabilized liquid tenside preparation comprising enzymes (a component comprising a multiply substituted benzyl carboxylic acid comprising a carboxyl group on at least two carbon atoms of the benzyl radical is used for stabilizing the hydrolytic enzyme) [Europäische Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2012
SP  - 1
EP  - 16
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - PAT
A1  - Siegert, Petra
A1  - Merkel, Marion
A1  - Hellmuth, Hendrik
A1  - O'Connell, Timothy
A1  - Maurer, Karl-Heinz
T1  - Stabilisierte flüssige enzymhaltige Tensidzubereitung (Einsatz einer das hydrolytische Enzym stabilisierende Komponente, die eine Phthaloylglutaminsäure und/oder eine Phthaloylasparaginsäure umfasst) [Offenlegungsschrift]
T1  - Stabilized liquid tenside preparation comprising enzymes (a component comprising a phthaloyl glutamine acid and/or a phthaloyl asparagine acid is used for stablizing the hydrolytic enzyme) [Europäische Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2012
SP  - 1
EP  - 16
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - PAT
A1  - Siegert, Petra
A1  - Merkel, Marion
A1  - Hellmuth, Hendrik
A1  - O'Connell, Timothy
A1  - Maurer, Karl-Heinz
T1  - Stabilisierte flüssige enzymhaltige Tensidzubereitung (Einsatz einer das hydrolytische Enzym stabilisierende Komponente, die eine Aminophthalsäure umfasst) [Offenlegungsschrift]
T1  - Stabilized liquid tenside preparation comprising enzymes (a component comprising an aminophthalic acid is used for stabilizing the hydrolytic enzyme) [Europäische Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2012
SP  - 1
EP  - 16
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - PAT
A1  - Siegert, Petra
A1  - Merkel, Marion
A1  - Hellmuth, Hendrik
A1  - O'Connell, Timothy
A1  - Maurer, Karl-Heinz
T1  - Stabilisierte flüssige enzymhaltige Tensidzubereitung (Einsatz einer das hydrolytische Enzym stabilisierende Komponente, die eine Oligoamino-biphenyl-oligocarbonsäure umfasst) [Offenlegungsschrift]
T1  - Stabilized liquid tenside preparation comprising enzymes (a component comprising an oligoamino-biphenyl-oligocarboxylic acid is used for stabilizing the hydrolytic enzyme) [Europäische Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2012
SP  - 1
EP  - 16
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - JOUR
A1  - Raue, Markus
A1  - Wambach, M.
A1  - Glöggler, S.
A1  - Grefen, Dana
A1  - Kaufmann, R.
A1  - Abetz, C.
A1  - Georgopanos, P.
A1  - Handge, U. A.
A1  - Mang, Thomas
A1  - Blümich, B.
A1  - Abetz, V.
T1  - Investigation of historical hard rubber ornaments of Charles Goodyear
JF  - Macromolecular chemistry and physics
Y1  - 2014
SN  - 1022-1352
VL  - Vol. 215
IS  - No. 3
SP  - 245
EP  - 254
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Seifarth, Volker
A1  - Goßmann, Matthias
A1  - Grosse, J. O.
A1  - Becker, C.
A1  - Heschel, I.
A1  - Artmann, Gerhard
A1  - Temiz Artmann, Aysegül
T1  - Development of a Bioreactor to Culture Tissue Engineered Ureters Based on the Application of Tubular OPTIMAIX 3D Scaffolds
JF  - Urologia Internationalis
Y1  - 2015
U6  - https://doi.org/10.1159/000368419
SN  - 0042-1138
VL  - 2015
IS  - 95
SP  - 106
EP  - 113
PB  - Karger
CY  - Basel
ER  - 
TY  - JOUR
A1  - Pilas, Johanna
A1  - Iken, Heiko
A1  - Selmer, Thorsten
A1  - Keusgen, Michael
A1  - Schöning, Michael Josef
T1  - Development of a multi‐parameter sensor chip for the simultaneous detection of organic compounds in biogas processes
JF  - Physica status solidi (a)
N2  - An enzyme-based multi-parameter biosensor is developed for monitoring the concentration of formate, d-lactate, and l-lactate in biological samples. The sensor is based on the specific dehydrogenation by an oxidized β-nicotinamide adenine dinucleotide (NAD+)-dependent dehydrogenase (formate dehydrogenase, d-lactic dehydrogenase, and l-lactic dehydrogenase, respectively) in combination with a diaphorase from Clostridium kluyveri (EC 1.8.1.4). The enzymes are immobilized on a platinum working electrode by cross-linking with glutaraldehyde (GA). The principle of the determination scheme in case of l-lactate is as follows: l-lactic dehydrogenase (l-LDH) converts l-lactate into pyruvate by reaction with NAD+. In the presence of hexacyanoferrate(III), the resulting reduced β-nicotinamide adenine dinucleotide (NADH) is then regenerated enzymatically by diaphorase. The electrochemical detection is based on the current generated by oxidation of hexacyanoferrate(II) at an applied potential of +0.3 V vs. an Ag/AgCl reference electrode. The biosensor will be electrochemically characterized in terms of linear working range and sensitivity. Additionally, the successful practical application of the sensor is demonstrated in an extract from maize silage.
Y1  - 2015
U6  - https://doi.org/10.1002/pssa.201431894
SN  - 1862-6319
VL  - 212
IS  - 6
SP  - 1306
EP  - 1312
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Breuer, Lars
A1  - Raue, Markus
A1  - Kirschbaum, M.
A1  - Mang, Thomas
A1  - Schöning, Michael Josef
A1  - Thoelen, R.
A1  - Wagner, Torsten
T1  - Light-controllable polymeric material based on temperature-sensitive hydrogels with incorporated graphene oxide
JF  - Physica status solidi (a)
N2  - Poly(N-isopropylacrylamide) (PNIPAAm) hydrogel films with incorporated graphene oxide (GO) were developed and tested as light-stimulated actuators. GO dispersions were synthesized via Hummers method and characterized toward their optical properties and photothermal energy conversion. The hydrogels were prepared by means of photopolymerization. In addition, the influence of GO within the hydrogel network on the lower critical solution temperature (LCST) was investigated by differential scanning calorimetry (DSC). The optical absorbance and the response to illumination were determined as a function of GO concentration for thin hydrogel films. A proof of principle for the stimulation with light was performed.
Y1  - 2015
U6  - https://doi.org/10.1002/pssa.201431944
SN  - 1862-6319
VL  - 212
IS  - 6
SP  - 1368
EP  - 1374
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Kusch, Peter
A1  - Rieser, Claudia
A1  - Knupp, Gerd
A1  - Mang, Thomas
T1  - Characterization of copolymers of methacrylic acid with poly(ethylene glycol) methyl ether methacrylate macromonomers by analytical pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS)
JF  - Journal of Analytical and Applied Pyrolysis
Y1  - 2015
U6  - https://doi.org/10.1016/j.jaap.2015.03.003
SN  - 0165-2370
VL  - Vol. 113
SP  - 412
EP  - 418
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schiffels, Johannes
A1  - Selmer, Thorsten
T1  - A flexible toolbox to study protein-assisted metalloenzyme assembly in vitro
JF  - Biotechnology and Bioengineering
Y1  - 2015
U6  - https://doi.org/10.1002/bit.25658
SN  - 1097-0290
VL  - 112
IS  - 11
SP  - 2360
EP  - 2372
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Voigt, Birgit
A1  - Albrecht, Dirk
A1  - Sievers, Susanne
A1  - Becher, Dörte
A1  - Bongaerts, Johannes
A1  - Evers, Stefan
A1  - Schweder, Thomas
A1  - Maurer, Karl-Heinz
A1  - Hecker, Michael
T1  - High-resolution proteome maps of Bacillus licheniformis cells growing in minimal medium
JF  - Proteomics
Y1  - 2015
U6  - https://doi.org/10.1002/pmic.201400504
SN  - 1615-9861
VL  - 15
IS  - 15
SP  - 2629
EP  - 2633
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Molinnus, Denise
A1  - Bäcker, Matthias
A1  - Siegert, Petra
A1  - Willenberg, H.
A1  - Poghossian, Arshak
A1  - Keusgen, M.
A1  - Schöning, Michael Josef
T1  - Detection of Adrenaline Based on Substrate Recycling Amplification
JF  - Procedia Engineering
N2  - An amperometric enzyme biosensor has been applied for the detection of adrenaline. The adrenaline biosensor has been prepared by modification of an oxygen electrode with the enzyme laccase that operates at a broad pH range between pH 3.5 to pH 8. The enzyme molecules were immobilized via cross-linking with glutaraldehyde. The sensitivity of the developed adrenaline biosensor in different pH buffer solutions has been studied.
Y1  - 2015
U6  - https://doi.org/10.1016/j.proeng.2015.08.708
SN  - 1877-7058
N1  - Eurosensors 2015
VL  - 120
SP  - 540
EP  - 543
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Pilas, Johanna
A1  - Mariano, K.
A1  - Keusgen, M.
A1  - Selmer, Thorsten
A1  - Schöning, Michael Josef
T1  - Optimization of an Enzyme-based Multi-parameter Biosensor for Monitoring Biogas Processes
JF  - Procedia Engineering
Y1  - 2015
U6  - https://doi.org/10.1016/j.proeng.2015.08.702
SN  - 1877-7058
N1  - Part of special issue "Eurosensors 2015"
VL  - 120
SP  - 532
EP  - 535
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - PAT
A1  - O'Connell, Timothy
A1  - Siegert, Petra
A1  - Maurer, Karl-Heinz
A1  - Schiedel, Marc-Steffen
A1  - Vockenroth, Inga Kerstin
T1  - Method for improving the cleaning action of a detergent or cleaning agent [Internationale Patentanmeldung]
T1  - Verfahren zur Verbesserung der Reinigungsleistung eines Wasch- oder Reinigungsmittels
Y1  - 2010
SP  - 1
EP  - 15
PB  - WIPO
CY  - Genf
ER  - 
TY  - JOUR
A1  - Cehreli, Ruksan
A1  - Akpinar, Hale
A1  - Temiz Artmann, Aysegül
A1  - Sagol, Ozgul
T1  - Effects of Glutamine and Omega-3 Fatty Acids on Erythrocyte Deformability and Oxidative Damage in Rat Model of Enterocolitis
JF  - Gastroenterology Research
Y1  - 2015
U6  - https://doi.org/10.14740/gr683w
SN  - 1918-2813
VL  - 8
IS  - 5
SP  - 265
EP  - 273
ER  - 
TY  - CHAP
A1  - Srivastava, Alok
A1  - Knolle, F.
A1  - Schnug, E.
A1  - Scherer, Ulrich W.
T1  - Study of Trace Elements in Water Bodies of the Harz Mts. Region, Germany using Total Reflection X Ray Fluorescence (TXRF)
T2  - DAE-BRNS 12th National Symposium on Nuclear and Radiochemistry NUCAR 2015, Feb. 9-13, Mumbai, India, Mumbai, India; 02/2015
Y1  - 2015
SP  - 355
EP  - 356
ER  - 
TY  - CHAP
A1  - Srivastava, Alok
A1  - Knolle, Friedhart
A1  - Hoyler, Friedrich
A1  - Scherer, Ulrich W.
A1  - Schnug, Ewald
T1  - Uranium Toxicity in the State of Punjab in North-Western India
T2  - Management of Natural Resources in a Changing Environment
N2  - Lately there has been an increasing concern about uranium toxicity in some districts of Punjab State located in the North Western part of India after the publication of a report (Blaurock-Busch et al. 2010) which showed that the concentration of uranium in hair and urine of children suffering from physical deformities, neurological and mental disorder from Malwa region (Fig. 1) of Punjab State was manifold higher than the reference ranges. A train which connects the affected region with the nearby city of Bikaner which has a Cancer Hospital has been nicknamed as Cancer Express due to the frenzy generated on account of uranium related toxicity.
Y1  - 2015
SN  - 978-3-319-12559-6
U6  - https://doi.org/10.1007/978-3-319-12559-6_21
SP  - 271
EP  - 275
PB  - Springer
CY  - Cham
ER  - 
TY  - BOOK
A1  - Müller, Bodo
A1  - Rath, Walter
T1  - Formulierung von Kleb- und Dichtstoffen: das kompetente Lehrbuch für Studium und Praxis
Y1  - 2015
SN  - 978-3-86630-605-9
PB  - Vincentz Network
CY  - Hannover
ET  - 3., vollst. überarb. Aufl.
ER  - 
TY  - PAT
A1  - Berndt, Heinz
A1  - Höcker, Hartwig
A1  - Kuropka, Rolf
A1  - Kinkel, Joachim
T1  - Silanderivate : Europäische Patenschrift / Offenlegungsschrift
T1  - Silane derivatives : Europäische Patenschrift / Offenlegungsschrift
Y1  - 1991
PB  - Europäisches Patentamt / Deutsches Patent- und Markenamt
CY  - Den Hague / München
ER  - 
TY  - PAT
A1  - Berndt, Heinz
A1  - Höcker, Hartwig
A1  - Kuropka, Rolf
A1  - Kinkel, Joachim
T1  - Silane coated inorganic materials for chromatography : United States Patent
Y1  - 1991
PB  - [The United States Patent and Trademark Office]
CY  - [Alexandria, VA u.a.]
ER  - 
TY  - JOUR
A1  - Handtke, Stefan
A1  - Schroeter, Rebecca
A1  - Jürgen, Britta
A1  - Methling, Karen
A1  - Schlüter, Rabea
A1  - Albrecht, Dirk
A1  - Hijum, Sacha A. F. T. van
A1  - Bongaerts, Johannes
A1  - Maurer, Karl-Heinz
A1  - Lalk, Michael
A1  - Schweder, Thomas
A1  - Hecker, Michael
A1  - Voigt, Birgit
T1  - Bacillus pumilus reveals a remarkably high resistance to hydrogen peroxide provoked oxidative stress
JF  - PLOS one
N2  - Bacillus pumilus is characterized by a higher oxidative stress resistance than other comparable industrially relevant Bacilli such as B. subtilis or B. licheniformis. In this study the response of B. pumilus to oxidative stress was investigated during a treatment with high concentrations of hydrogen peroxide at the proteome, transcriptome and metabolome level. Genes/proteins belonging to regulons, which are known to have important functions in the oxidative stress response of other organisms, were found to be upregulated, such as the Fur, Spx, SOS or CtsR regulon. Strikingly, parts of the fundamental PerR regulon responding to peroxide stress in B. subtilis are not encoded in the B. pumilus genome. Thus, B. pumilus misses the catalase KatA, the DNA-protection protein MrgA or the alkyl hydroperoxide reductase AhpCF. Data of this study suggests that the catalase KatX2 takes over the function of the missing KatA in the oxidative stress response of B. pumilus. The genome-wide expression analysis revealed an induction of bacillithiol (Cys-GlcN-malate, BSH) relevant genes. An analysis of the intracellular metabolites detected high intracellular levels of this protective metabolite, which indicates the importance of bacillithiol in the peroxide stress resistance of B. pumilus.
Y1  - 2014
U6  - https://doi.org/10.1371/journal.pone.0085625
SN  - 1932-6203
VL  - 9
IS  - 1
PB  - PLOS
CY  - San Francisco
ER  - 
TY  - JOUR
A1  - Nachtrodt, Frederik
A1  - Tietsch, Wolfgang
A1  - Mostacci, Domiziano
A1  - Scherer, Ulrich W.
T1  - Set-up and first operation of a plasma oven for treatment of low level radioactive wastes
JF  - Nuclear technology and radiation protection
Y1  - 2014
U6  - https://doi.org/10.2298/NTRP140SS47N
SN  - 1451-3994
VL  - 29
IS  - Suppl.
SP  - 47
EP  - 51
PB  - VINČA Institute of Nuclear Sciences
CY  - Belgrad
ER  - 
TY  - CHAP
A1  - Frotscher, Ralf
A1  - Goßmann, Matthias
A1  - Raatschen, Hans-Jürgen
A1  - Temiz Artmann, Aysegül
A1  - Staat, Manfred
T1  - Simulation of cardiac cell-seeded membranes using the edge-based smoothed FEM
T2  - Shell and membrane theories in mechanics and biology. (Advanced structured materials ; 45)
N2  - We present an electromechanically coupled Finite Element model for cardiac tissue. It bases on the mechanical model for cardiac tissue of Hunter et al. that we couple to the McAllister-Noble-Tsien electrophysiological model of purkinje fibre cells. The corresponding system of ordinary differential equations is implemented on the level of the constitutive equations in a geometrically and physically nonlinear version of the so-called edge-based smoothed FEM for plates. Mechanical material parameters are determined from our own pressure-deflection experimental setup. The main purpose of the model is to further examine the experimental results not only on mechanical but also on electrophysiological level down to ion channel gates. Moreover, we present first drug treatment simulations and validate the model with respect to the experiments.
Y1  - 2015
SN  - 978-3-319-02534-6 ; 978-3-319-02535-3
SP  - 187
EP  - 212
PB  - Springer
CY  - Heidelberg
ER  - 
TY  - JOUR
A1  - Handtke, Stefan
A1  - Volland, Sonja
A1  - Methling, Karen
A1  - Albrecht, Dirk
A1  - Becher, Dörte
A1  - Nehls, Jenny
A1  - Bongaerts, Johannes
A1  - Maurer, Karl-Heinz
A1  - Lalk, Michael
A1  - Liesegang, Heiko
A1  - Voigt, Birgit
A1  - Daniel, Rolf
A1  - Hecker, Michael
T1  - Cell physiology of the biotechnological relevant bacterium Bacillus pumilus - An omics-based approach
JF  - Journal of Biotechnology
N2  - Members of the species Bacillus pumilus get more and more in focus of the biotechnological industry as potential new production strains. Based on exoproteome analysis, B. pumilus strain Jo2, possessing a high secretion capability, was chosen for an omics-based investigation. The proteome and metabolome of B. pumilus cells growing either in minimal or complex medium was analyzed. In total, 1542 proteins were identified in growing B. pumilus cells, among them 1182 cytosolic proteins, 297 membrane and lipoproteins and 63 secreted proteins. This accounts for about 43% of the 3616 proteins encoded in the B. pumilus Jo2 genome sequence. By using GC–MS, IP-LC/MS and H NMR methods numerous metabolites were analyzed and assigned to reconstructed metabolic pathways. In the genome sequence a functional secretion system including the components of the Sec- and Tat-secretion machinery was found. Analysis of the exoproteome revealed secretion of about 70 proteins with predicted secretion signals. In addition, selected production-relevant genome features such as restriction modification systems and NRPS clusters of B. pumilus Jo2 are discussed.
Y1  - 2014
U6  - https://doi.org/10.1016/j.jbiotec.2014.08.028
SN  - 1873-4863 (E-Journal); 0168-1656 (Print)
IS  - 192(A)
SP  - 204
EP  - 214
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - PAT
A1  - Bessler, Cornelius
A1  - Evers, Stefan
A1  - Maurer, Karl-Heinz
A1  - Merkel, Marion
A1  - Siegert, Petra
A1  - Weber, Angrit
A1  - Wieland, Susanne
T1  - Leistungsverbesserte Proteasen und Wasch- und Reinigungsmittel enthaltend diese Proteasen [Offenlegungsschrift]
T1  - Improved-performance proteases and detergents and cleaning agents comprising said proteases [Internationale Patentanmeldung]
Y1  - 2009
SP  - 1
EP  - 41
PB  - Deutsches Patent- und Markenamt / WIPO
CY  - München / Genf
ER  - 
TY  - PAT
A1  - Bessler, Cornelius
A1  - Maurer, Karl-Heinz
A1  - Merkel, Marion
A1  - Siegert, Petra
A1  - Wieland, Susanne
T1  - Subtilisin from Bacillus Pumilus and detergent and cleaning agents containing said novel subtilisin [US Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2009
SP  - 1
EP  - 39
PB  - USPTO; WIPO
CY  - Washington; Genf
ER  - 
TY  - PAT
A1  - Bessler, Cornelius
A1  - Maurer, Karl-Heinz
A1  - Merkel, Marion
A1  - Siegert, Petra
A1  - Wieland, Susanne
T1  - Subtilisin aus Bacillus pumilus und Wasch- und Reinigungsmittel enthaltend dieses neue Subtilisin [Offenlegungsschrift]
T1  - Subtilisin from Bacillus pumilus and washing and cleaning agents containing said novel subtilisin [Europäische Patentanmeldung / Internationale Patentanmeldung / Kanadische Patentanmeldung]
Y1  - 2007
SP  - 1
EP  - 47
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO / CIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - PAT
A1  - Berg, Gabriele
A1  - Bessler, Cornelius
A1  - Gerlach, Jochen
A1  - Gübitz, Georg
A1  - Heumann, Sonja
A1  - Karl, Wolfgang
A1  - Maurer, Karl-Heinz
A1  - Remler, Peter
A1  - Ribitsch, Doris
A1  - Schwab, Helmut
A1  - Siegert, Petra
A1  - Wieland, Susanne
T1  - Mittel enthaltend Proteasen aus Stenotrophomonas maltophilia [Offenlegungsschrift]
T1  - Agents containing proteases from Stenotrophomonas maltophilia [Europäische Patentanmeldung / US Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2009
SP  - 1
EP  - 47
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt / USPTO / WIPO
CY  - München / Den Hague / Washington / Genf
ER  - 
TY  - PAT
A1  - Siegert, Petra
A1  - Wieland, Susanne
A1  - Engelskirchen, Julia
A1  - Merkel, Marion
A1  - Maurer, Karl-Heinz
A1  - Bessler, Cornelius
T1  - Neue Alkalische Protease aus Bacillus gibsonii und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease [Offenlegungsschrift]
T1  - Novel alkaline protease from Bacillus Gibsonii and washing and cleaning agents containing said novel alkaline protease [Europäische Patentanmeldung / US Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2008
SP  - 1
EP  - 51
PB  - Deutsches Patentamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - PAT
A1  - Merkel, Marion
A1  - Weber, Angrit
A1  - Siegert, Petra
A1  - Wieland, Susanne
A1  - Maurer, Karl-Heinz
A1  - Bessler, Cornelius
T1  - Neue Alkalische Protease aus Bacillus gibsonii und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease [Offenlegungsschrift]
T1  - Novel alkaline protease from Bacillus Gibsonii and washing and cleaning agents containing said novel alkaline protease [Internationale Patentanmeldung]
Y1  - 2007
SP  - 1
EP  - 46
PB  - Deutsches Patent- und Markenamt / WIPO
CY  - München / Genf
ER  - 
TY  - PAT
A1  - O'Connell, Timothy
A1  - Hoven, Nina
A1  - Siegert, Petra
A1  - Maurer, Karl-Heinz
T1  - Amadoriasen in Wasch- und Reinigungsmitteln [Offenlegungsschrift]
T1  - Amadoriases in washing and cleaning products [Europäische Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2007
SP  - 1
EP  - 45
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  - 
TY  - PAT
A1  - Schulze zur Wiesche, Erik
A1  - Otto, Ralf
A1  - Kleen, Astrid
A1  - Hollenberg, Detlef
A1  - Sättler, Andrea
A1  - Siegert, Petra
A1  - Boßmann, Britta
T1  - Verfahren zur dauerhaften Ausrüstung keratinischer Fasern mit Pflegewirkstoffen durch Carboxylesterhydrolasen [Offenlegungsschrift]
T1  - Method for the permanent deposition of conditioning agents on keratinic fibres using carboxylester hydrolases [Europäische Patentanmeldung]
Y1  - 2005
SP  - 1
EP  - 13
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt
CY  - München / Den Hague
ER  - 
TY  - PAT
A1  - Kluin, Cornelia
A1  - Maurer, Karl-Heinz
A1  - Banowski, Bernhard
A1  - Bessler, Cornelius
A1  - Siegert, Petra
T1  - Verwendung von Siderophoren gegen Geruchskeime [Offenlegungsschrift]
T1  - Use of siderophores for control of odor-producing bacteria, particularly for treating or preventing body odor, act by depriving bacteria of iron
Y1  - 2005
SP  - 1
EP  - 32
PB  - Deutsches Patent- und Markenamt
CY  - München
ER  - 
TY  - PAT
A1  - Bankowski, Bernhard
A1  - Hoffmann, Daniele
A1  - Wadle, Armin
A1  - Siegert, Petra
A1  - Sättler, Andrea
A1  - Gerke, Thomas
T1  - Beta-Glucuronidase-Inhibitoren in Deodorantien und Antitranspirantien [Offenlegungsschrift]
T1  - Beta-Glucuronidase inhibitors for use in deodorants and antiperspirants [Europäische Patentanmeldung / Internationale Patentanmeldung]
Y1  - 2003
SP  - 1
EP  - 24
PB  - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO
CY  - München / Den Hague / Genf
ER  -