TY  - JOUR
A1  - Siqueira, José R. Jr.
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Zucolotto, Valtencir
A1  - Oliveira, Osvaldo N. Jr.
A1  - Schöning, Michael Josef
T1  - Associating biosensing properties with the morphological structure of multilayers containing carbon nanotubes on field-effect devices
JF  - Physica Status Solidi (A)
N2  - The control of molecular architecture provided by the layer-by-layer (LbL) technique has led to enhanced biosensors, in which advantageous features of distinct materials can be combined. Full optimization of biosensing performance, however, is only reached if the film morphology is suitable for the principle of detection of a specific biosensor. In this paper, we report a detailed morphology analysis of LbL films made with alternating layers of single-walled carbon nanotubes (SWNTs) and polyamidoamine (PAMAM) dendrimers, which were then covered with a layer of penicillinase (PEN). An optimized performance to detect penicillin G was obtained with 6-bilayer SWNT/PAMAM LbL films deposited on p-Si-SiO2-Ta2O5 chips, used in biosensors based on a capacitive electrolyte-insulator-semiconductor (EIS) and a light-addressable potentiometric sensor (LAPS) structure, respectively. Field-emission scanning electron microscopy (FESEM) and atomic force microscopy (AFM) images indicated that the LbL films were porous, with a large surface area due to interconnection of SWNT into PAMAM layers. This morphology was instrumental for the adsorption of a larger quantity of PEN, with the resulting LbL film being highly stable. The experiments to detect penicillin were performed with constant-capacitance (ConCap) and constant-current (CC) measurements for EIS and LAPS sensors, respectively, which revealed an enhanced detection signal and sensitivity of ca. 100 mV/decade for the field-effect sensors modified with the PAMAM/SWNT LbL film. It is concluded that controlling film morphology is essential for an enhanced performance of biosensors, not only in terms of sensitivity but also stability and response time.
Y1  - 2010
U6  - https://doi.org/10.1002/pssa.200983301
SN  - 1862-6300
N1  - Special Issue: Engineering of Functional Interfaces EnFI 2009
VL  - 207
IS  - 4
SP  - 781
EP  - 786
PB  - Wiley-VCH
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Tran, L.
A1  - Waluga, C.
A1  - Behr, Marek
A1  - Oedekoven, B.
A1  - Mottaghy, K.
T1  - Model-based Numerical Analysis of Platelet Adhesion, Thrombus Growth and Aggregation for Assist Devices
JF  - The International Journal of Artificial Organs. 32 (2009), H. 7
Y1  - 2009
SN  - 0391-3988
N1  - Abstracts - Oral Presentations: XXXVI Annual ESAO Congress, 2-5 September 2009, Compiègne - France; European Society of Artificial Organs (ESAO), Compiegne, France, September 2-5, 2009
SP  - 398
EP  - 398
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Schaub, A.
A1  - Zundel, A.
A1  - Beckers, Leah
A1  - Schubert, J.
A1  - Zander, W.
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Pulsed laser deposition as a novel thin film preparation method for silicon-based field effect sensors
JF  - Proceedings of the 25th European Solid State Device Research Conference : the Netherlands Congress Centre, The Hague, the Netherlands, 25th - 27th September 1995 / ESSDERC '95. Ed. by H. C. de Graaff
Y1  - 1995
SN  - 2-86332-182-X
N1  - ESSDERC ; (25, 1995, 's-Gravenhage) ; European Solid State Device Research Conference (ESSDERC) ; (25 : ; 1995.09.25-27 : ; Den Haag)
SP  - 601
EP  - 604
PB  - Ed. Frontières
CY  - Gif-sur-Yvette
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Behr, Marek
A1  - Arora, D.
A1  - Coronado, O.
A1  - Pasquali, M.
T1  - CFD Analysis of MicroMed Debakey Pump and Hemolysis Prediction / Behbahani, M. ; Behr, M. ; Arora, D. ; Coronado, O. ; Pasquali, M.
JF  - Artificial Organs. 30 (2006), H. 11
Y1  - 2006
SN  - 1525-1594
N1  - Abstracts 14th Congress of the International Society for Rotary Blood Pumps, Leuven, Belgium, August 31–September 2, 2006 ; S7-4
SP  - A45
EP  - A46
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Behr, Marek
A1  - Hormes, M.
A1  - Steinseifer, U.
A1  - Arora, D.
A1  - Coronado, O.
A1  - Pasquali, M.
T1  - A Review of Computational Fluid Dynamics Analysis of Blood Pumps
JF  - European Journal of Applied Mathematics. 20 (2009), H. 4
Y1  - 2009
SP  - 363
EP  - 397
PB  - Cambridge Univ. Press
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Tran, L.
A1  - Jockenhövel, S.
A1  - Behr, Marek
A1  - Mottaghy, K.
T1  - Numerical prediction of thrombocyte reactions for application to a vascular flow model
JF  - British Journal of Surgery
Y1  - 2011
SN  - 1365-2168
N1  - 46th Congress of the European Society for Surgical Research, Aachen, Germany, 25-28 May 2011 ; ESSR Abstracts 2011 ; Oral Sessions OP10-5
VL  - 98
IS  - S5
SP  - S17
PB  - Oxford University Press
CY  - Oxford
ER  - 
TY  - CHAP
A1  - Bäcker, Matthias
A1  - Koch, Claudia
A1  - Geiger, Fania
A1  - Eber, Fabian
A1  - Gliemann, Hartmut
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - A New Class of Biosensors Based on Tobacco Mosaic Virus and Coat Proteins as Enzyme Nanocarrier
T2  - Procedia Engineering
Y1  - 2016
U6  - https://doi.org/10.1016/j.proeng.2016.11.228
SN  - 1877-7058
N1  - Proceedings of the 30th anniversary Eurosensors Conference – Eurosensors 2016, 4-7. Sepember 2016, Budapest, Hungary
VL  - Vol. 168
SP  - 618
EP  - 621
ER  - 
TY  - JOUR
A1  - Ullrich, Sebastian
A1  - Grottke, Oliver
A1  - Rossaint, Rolf
A1  - Staat, Manfred
A1  - Deserno, Thomas M.
A1  - Kuhlen, Torsten
T1  - Virtual Needle Simulation with Haptics for Regional Anaesthesia
Y1  - 2010
N1  - IEEE Virtual Reality 2010, Workshop on Medical Virtual Environments, Waltham, MA, USA, March 21, 2010
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Waluga, C.
A1  - Arlt, S.
A1  - Behr, Marek
A1  - Mottaghy, K.
T1  - Computational Analysis of Platelet Aggregation in a Taylor-Couette System
JF  - The International Journal of Artificial Organs. 31 (2008), H. 7
Y1  - 2008
SN  - 0391-3988
N1  - Posterpresentation ; European Society of Artificial Organs (ESAO), Geneva, Switzerland
SP  - 643
ER  - 
TY  - JOUR
A1  - Probst, M.
A1  - Behbahani, Mehdi
A1  - Borrmann, E.
A1  - Elgeti, S.
A1  - Nicolai, M.
A1  - Behr, Marek
T1  - Hemodynamic Modeling for Numerical Analysis and Design of Medical Devices
Y1  - 2010
N1  - Posterpresentation ; NIC Symposium 2010 ; 24 - 25 February 2010 Jülich, Germany
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Mai, A.
A1  - Bergmann, B.
A1  - Waluga, C.
A1  - Behr, Marek
A1  - Tran, L.
A1  - Vonderstein, K.
A1  - Mottaghy, K.
T1  - Modeling and Numerical Simulation of Blood Damage
Y1  - 2010
N1  - Posterpresentation ; Umbrella Symposium "Modelling and Simulation in Medicine, Engineering and Sciences", Forschungszentrum Jülich, January 18-20, 2010
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Waluga, C.
A1  - Stock, S.
A1  - Mai, A.
A1  - Bergmann, B.
A1  - Behr, Marek
A1  - Tran, L.
A1  - Vonderstein, K.
A1  - Scheidt, H.
A1  - Oedekoven, B.
A1  - Mottaghy, K.
T1  - Modelling and Numerical Analysis of Platelet Reactions and Surface Thrombus Growth
Y1  - 2009
N1  - Posterpresentation ; European Society of Biomaterials (ESB), Lausanne, Switzerland, September 7-10, 2009
ER  - 
TY  - JOUR
A1  - Kowalski, Julia
A1  - Linder, Peter
A1  - Zierke, Simon
A1  - von Wulfen, Benedikt
A1  - Clemens, Joachim
A1  - Konstantinidis, Konstantinos
A1  - Ameres, Gerald
A1  - Hoffmann, Ruth
A1  - Mikucki, Jill A.
A1  - Tulaczyk, Slawek M.
A1  - Funke, Oliver
A1  - Blandfort, Daniel
A1  - Espe, Clemens
A1  - Feldmann, Marco
A1  - Francke, Gero
A1  - Hiecker, S.
A1  - Plescher, Engelbert
A1  - Schöngarth, Sarah
A1  - Dachwald, Bernd
A1  - Digel, Ilya
A1  - Artmann, Gerhard
A1  - Eliseev, Dmitry
A1  - Heinen, Dirk
A1  - Scholz, Franziska
A1  - Wiebusch, Christopher H.
A1  - Macht, Sabine
A1  - Bestmann, Ulf
A1  - Reineking, Thomas
A1  - Zetzsche, Christoph
A1  - Schill, Kerstin
A1  - Förstner, Roger
A1  - Niedermeier, Herbert
A1  - Szumski, Arkadiusz
A1  - Eissfeller, Bernd
A1  - Naumann, Uwe
A1  - Helbing, Klaus
T1  - Navigation technology for exploration of glacier ice with maneuverable melting probes
JF  - Cold Regions Science and Technology
N2  - The Saturnian moon Enceladus with its extensive water bodies underneath a thick ice sheet cover is a potential candidate for extraterrestrial life. Direct exploration of such extraterrestrial aquatic ecosystems requires advanced access and sampling technologies with a high level of autonomy. A new technological approach has been developed as part of the collaborative research project Enceladus Explorer (EnEx). The concept is based upon a minimally invasive melting probe called the IceMole. The force-regulated, heater-controlled IceMole is able to travel along a curved trajectory as well as upwards. Hence, it allows maneuvers which may be necessary for obstacle avoidance or target selection. Maneuverability, however, necessitates a sophisticated on-board navigation system capable of autonomous operations. The development of such a navigational system has been the focal part of the EnEx project. The original IceMole has been further developed to include relative positioning based on in-ice attitude determination, acoustic positioning, ultrasonic obstacle and target detection integrated through a high-level sensor fusion. This paper describes the EnEx technology and discusses implications for an actual extraterrestrial mission concept.
Y1  - 2016
U6  - https://doi.org/10.1016/j.coldregions.2015.11.006
SN  - 0165-232X
IS  - 123
SP  - 53
EP  - 70
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Berndsen, Lars
A1  - Schöning, Michael Josef
T1  - Chemical sensor as a physical sensor: ISFET-based flowvelocity, flow-direction and diffusion-coefficient sensor
JF  - Book of abstracts / ed. by J. Saneistr.
Y1  - 2002
SN  - 80-01-02576-4
N1  - Eurosensors ; (16, 2002, Praha)
SP  - 649
EP  - 652
PB  - Czech Technical University, Faculty of Electrical Engineering, Department of Measurement
CY  - Prague
ER  - 
TY  - JOUR
A1  - Murib, Mohammed Sharif
A1  - Yeap, Weng Siang
A1  - Martens, Daan
A1  - Liu, Xianjie
A1  - Bienstman, Peter
A1  - Fahlman, M.
A1  - Schöning, Michael Josef
A1  - Michiels, Luc
A1  - Haenen, Ken
A1  - Serpengüzel, Ali
A1  - Wagner, Patrick
T1  - Photonic studies on polymer-coated sapphire-spheres : a model system for biological ligands
JF  - Sensors and actuators A: Physical
N2  - In this study we show an optical biosensor concept, based on elastic light scattering from sapphire microspheres. Transmitted and elastic scattering intensity of the microspheres (radius 500 μm, refractive index 1.77) on an optical fiber half coupler is analyzed at 1510 nm. The 0.43 nm angular mode spacing of the resonances is comparable to the angular mode spacing value estimated using the optical size of the microsphere. The spectral linewidths of the resonances are in the order of 0.01 nm, which corresponds to quality factors of approximately 105. A polydopamine layer is used as a functionalizing agent on sapphire microspherical resonators in view of biosensor implementation. The varying layer thickness on the microsphere is determined as a function of the resonance wavelength shift. It is shown that polymer functionalization has a minor effect on the quality factor. This is a promising step toward the development of an optical biosensor.
Y1  - 2015
U6  - https://doi.org/10.1016/j.sna.2014.11.024
SN  - 1873-3069 (E-Journal); 0924-4247 (Print)
VL  - 222
SP  - 212
EP  - 219
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Mansurov, Zulkhair A.
A1  - Digel, Ilya
A1  - Biisenbaev, M.
A1  - Savistkaya, I.
A1  - Kistaubaeva, Aida
A1  - Akimbekov, Nuraly S.
A1  - Zhubanova, Azhar Achmet
T1  - Bio-composite material on the basis of carbonized rice husk in biomedicine and environmental applications
JF  - Eurasian Chemico-Technological Journal
Y1  - 2012
U6  - https://doi.org/10.18321/ectj105
SN  - 2522-4867
VL  - 14
IS  - 2
SP  - 115
EP  - 131
PB  - Institute of Combustion Problems
CY  - Almaty
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Berndsen, Lars
A1  - Schultze, J. W.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - „High order“ hybrid sensor module based on an identical transducer principle
JF  - Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler
Y1  - 2001
SN  - 1-56677-351-2
N1  - International Symposium: Chemical and Biological Sensors and Analytical Methods ; (2 : 2001.)
SP  - 143
EP  - 152
PB  - Electrochemical Society
CY  - Pennington, NJ
ER  - 
TY  - JOUR
A1  - Christiaens, Pieter
A1  - Abouzar, Maryam H.
A1  - Poghossian, Arshak
A1  - Wagner, Torsten
A1  - Bijnens, Nathalie
A1  - Williams, Oliver A.
A1  - Daenen, Michael
A1  - Haenen, Ken
A1  - Douthéret, Olivier
A1  - D'Haen, Jan
A1  - Mekhalif, Z.
A1  - Schöning, Michael Josef
A1  - Wagner, Patrick
T1  - pH sensitivity of nanocrystalline diamond films
JF  - Physica status solidi (A). 204 (2007), H. 9
Y1  - 2007
SN  - 0031-8965
SP  - 2925
EP  - 2930
ER  - 
TY  - JOUR
A1  - Christiaens, Pieter
A1  - Abouzar, Maryam H.
A1  - Poghossian, Arshak
A1  - Wagner, Torsten
A1  - Bijnens, Nathalie
A1  - Williams, Oliver A.
A1  - Daenen, Michael
A1  - Haenen, Ken
A1  - Schöning, Michael Josef
A1  - Wagner, Patrick
T1  - Nanocrystalline diamond-based field-effect capacitive pH sensor
JF  - Transducers '07 Eurosensors XXI : digest of technical papers ; the14th International Conference on Solid-State Sensors, Actuators and Microsystems, June 10-14, 2007, Lyon, France / Gilles Delapierre (Ed.)
Y1  - 2007
SN  - 1-4244-0841-5
N1  - Eurosensors 21, 2007, Lyon ; International Conference on Solid-State Sensors, Actuators and Microsystems 14, 2007, Lyon
SP  - 1891
EP  - 1894
PB  - IEEE
CY  - Piscataway
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Abouzar, Maryam H.
A1  - Razavi, Arash
A1  - Bäcker, Matthias
A1  - Bijnens, Nathalie
A1  - Williams, Oliver A.
A1  - Haenen, Ken
A1  - Moritz, Werner
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Nanocrystalline-diamond thin films with high pH and penicillin sensitivity prepared on a capacitive Si–SiO2 structure
JF  - Electrochimica Acta. 54 (2009), H. 25
Y1  - 2009
SN  - 0013-4686
SP  - 5981
EP  - 5985
ER  - 
TY  - JOUR
A1  - Abouzar, Maryam H.
A1  - Poghossian, Arshak
A1  - Razavi, Arash
A1  - Williams, Oliver A.
A1  - Bijnens, Nathalie
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Characterisation of capacitive field-effect sensors with a nanocrystalline-diamond film as transducer material for multi-parameter sensing
JF  - Biosensors and Bioelectronics. 24 (2009), H. 5
Y1  - 2009
SN  - 0956-5663
N1  - Selected Papers from the Tenth World Congress on Biosensors Shangai, China, May 14-16, 2008 ; Zeitschrift früher u.d.T. : Biosensors
SP  - 1298
EP  - 1304
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Krause, Robin
A1  - Block, Kirstin
A1  - Musahmeh, Mustafa
A1  - Mulchandani, Ashok
A1  - Wang, Joseph
T1  - A dual amperometric/potentiometric FIA-based biosensor for the distinctive detection of organophosphorus pesticides
JF  - Sensors and Actuators B. 95 (2003), H. 1-3
Y1  - 2003
SN  - 0925-4005
SP  - 291
EP  - 296
ER  - 
TY  - JOUR
A1  - Wang, J.
A1  - Krause, R.
A1  - Block, Kirstin
A1  - Musameh, M.
A1  - Mulchandani, A.
A1  - Schöning, Michael Josef
T1  - Flow injection amperometric detection of OP nerve agents based on organophosphorus-hydrolase biosensor detector
JF  - Biosensors & Bioelectronics. 18 (2003), H. 2-3
Y1  - 2003
SN  - 0956-5663
SP  - 255
EP  - 260
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Kloock, Joachim P.
A1  - Knobbe, D.-T.
A1  - Krause, R.
A1  - Block, Kirstin
A1  - Wang, J.
A1  - Mulchandani, A.
A1  - Keusgen, M.
T1  - Direktnachweis von Pestiziden und Cyanid mit elektrochemischen Enzymsensoren
JF  - Sensoren und Messsysteme 2004 : Tagung Ludwigsburg, 15. und 16. März 2004 / VDI-VDE-Gesellschaft Mess- und Automatisierungstechnik
Y1  - 2004
SN  - 3-18-091829-2
N1  - Auch erschienen als: VDI-Berichte ; 1829
SP  - 699
EP  - 706
PB  - VDI
CY  - Düsseldorf
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Krause, R.
A1  - Block, Kirstin
A1  - Musameh, M.
A1  - Mulchandani, A.
A1  - Wang, J.
T1  - A dual amperometric / potentiometric FIA-based biosensor for the distinctive detection of organophosphorus pesticides
JF  - Book of abstracts / ed. by J. Saneistr.
Y1  - 2002
SN  - 80-01-02576-4
N1  - Eurosensors ; (16, 2002, Praha)
SP  - 76
EP  - 79
PB  - Czech Technical University, Faculty of Electrical Engineering, Department of Measurement
CY  - Prague
ER  - 
TY  - JOUR
A1  - Akimbekov, Nuraly
A1  - Digel, Ilya
A1  - Zhubanova, Azhar
A1  - Tastambek, Kuanysh T.
A1  - Tepecik, Atakan
A1  - Sherelkhan, Dinara
T1  - Biotechnological potentials of surfactants in coal utilization: a review
JF  - Environmental Science and Pollution Research
N2  - The quest for scientifically advanced and sustainable solutions is driven by growing environmental and economic issues associated with coal mining, processing, and utilization. Consequently, within the coal industry, there is a growing recognition of the potential of microbial applications in fostering innovative technologies. Microbial-based coal solubilization, coal beneficiation, and coal dust suppression are green alternatives to traditional thermochemical and leaching technologies and better meet the need for ecologically sound and economically viable choices. Surfactant-mediated approaches have emerged as powerful tools for modeling, simulation, and optimization of coal-microbial systems and continue to gain prominence in clean coal fuel production, particularly in microbiological co-processing, conversion, and beneficiation. Surfactants (surface-active agents) are amphiphilic compounds that can reduce surface tension and enhance the solubility of hydrophobic molecules. A wide range of surfactant properties can be achieved by either directly influencing microbial growth factors, stimulants, and substrates or indirectly serving as frothers, collectors, and modifiers in the processing and utilization of coal. This review highlights the significant biotechnological potential of surfactants by providing a thorough overview of their involvement in coal biodegradation, bioprocessing, and biobeneficiation, acknowledging their importance as crucial steps in coal consumption.
KW  - Coal
KW  - Surfactants
KW  - Microorganisms
KW  - Biosolubilization
KW  - Biobeneficiation
Y1  - 2024
U6  - https://doi.org/10.1007/s11356-024-34892-5
SN  - 1614-7499
VL  - 31
SP  - 55099
EP  - 55118
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Freyer, Nils
A1  - Kempt, Hendrik
A1  - Klöser, Lars
T1  - Easy-read and large language models: on the ethical dimensions of LLM-based text simplification
JF  - Ethics and Information Technology
N2  - The production of easy-read and plain language is a challenging task, requiring well-educated experts to write context-dependent simplifications of texts. Therefore, the domain of easy-read and plain language is currently restricted to the bare minimum of necessary information. Thus, even though there is a tendency to broaden the domain of easy-read and plain language, the inaccessibility of a significant amount of textual information excludes the target audience from partaking or entertainment and restricts their ability to live life autonomously. Large language models can solve a vast variety of natural language tasks, including the simplification of standard language texts to easy-read or plain language. Moreover, with the rise of generative models like GPT, easy-read and plain language may be applicable to all kinds of natural language texts, making formerly inaccessible information accessible to marginalized groups like, a.o., non-native speakers, and people with mental disabilities. In this paper, we argue for the feasibility of text simplification and generation in that context, outline the ethical dimensions, and discuss the implications for researchers in the field of ethics and computer science.
KW  - Large language models
KW  - Easy read
KW  - AI ethics
KW  - Natural language processing
KW  - Accessibility
Y1  - 2024
U6  - https://doi.org/10.1007/s10676-024-09792-4
SN  - 1388-1957 (Print)
SN  - 1572-8439 (Online)
VL  - 26
PB  - Springer
CY  - Dortrecht
ER  - 
TY  - JOUR
A1  - Myburgh-Jacobsz, Catharina Elizabeth
A1  - Botha-Le Roux, Shani
A1  - Kotliar, Konstantin
A1  - Wentzel, Annemarie
A1  - Jacobs, Adriaan
A1  - De Boever, Patrick
A1  - Goswami, Nandu
A1  - Strijdom, Hans
A1  - Smith, Wayne
T1  - Retinal vessel functional responses in South Africans living with and without HIV: the EndoAfrica-NWU study
JF  - Microcirculation
Y1  - 2024
U6  - https://doi.org/10.1111/micc.12878
SN  - 1073-9688 (Print)
SN  - 1549-8719 (Online)
IS  - Early View
PB  - Wiley
CY  - Malden, MA
ER  - 
TY  - CHAP
A1  - Bohrn, Ulrich
A1  - Stütz, Evamaria
A1  - Fleischer, M.
A1  - Schöning, Michael Josef
A1  - Wagner, P.
ED  - Abdelghani, Adnane
ED  - Schöning, Michael Josef
T1  - Towards a paradigm change – mammalian cells as sensitive biosensor layers for the detection of unexpected toxic substances in air
T2  - Nanoscale Science and Technology (NS&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012
Y1  - 2012
SP  - 44
EP  - 44
ER  - 
TY  - JOUR
A1  - Seynnes, Olivier R.
A1  - Bojsen-Møller, Jens
A1  - Albracht, Kirsten
A1  - Arndt, Anton
A1  - Cronin, Neil J.
A1  - Finni, Taija
A1  - Magnusson, Stig Peter
T1  - Ultrasound-based testing of tendon mechanical properties: a critical evaluation
JF  - Journal of Applied Physiology
Y1  - 2015
U6  - https://doi.org/10.1152/japplphysiol.00849.2014
SN  - 8750-7587
VL  - 118
IS  - 2
SP  - 133
EP  - 141
ER  - 
TY  - JOUR
A1  - Bohrn, Ulrich
A1  - Stütz, Evamaria
A1  - Fuchs, Karen
A1  - Fleischer, M.
A1  - Schöning, Michael Josef
A1  - Wagner, P.
T1  - Monitoring of irritant gas using a whole-cell-based sensor system
JF  - Sensors and Actuators B: Chemical
N2  - Cell-based sensors for the detection of gases have long been underrepresented, due to the cellular requirement of being cultured in a liquid environment. In this work we established a cell-based gas biosensor for the detection of toxic substances in air, by adapting a commercial sensor chip (Bionas®), previously used for the measurement of pollutants in liquids. Cells of the respiratory tract (A549, RPMI 2650, V79), which survive at a gas phase in a natural context, are used as biological receptors. The physiological cell parameters acidification, respiration and morphology are continuously monitored in parallel. Ammonia was used as a highly water-soluble model gas to test the feasibility of the sensor system. Infrared measurements confirmed the sufficiency of the medium draining method. This sensor system provides a basis for many sensor applications such as environmental monitoring, building technology and public security.
Y1  - 2012
U6  - https://doi.org/10.1016/j.snb.2012.05.088
SN  - 0925-4005
VL  - 175
SP  - 208
EP  - 217
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Bohrn, Ulrich
A1  - Stütz, Evamaria
A1  - Fuchs, Karen
A1  - Fleischer, M.
A1  - Schöning, Michael Josef
A1  - Wagner, P.
T1  - Air Quality Monitoring using a Whole-Cell based Sensor System
JF  - Procedia Engineering. 25 (2011)
Y1  - 2011
SN  - 1877-7058
N1  - EurosensorsXXV ; Proc. Eurosensors XXV, September 4-7, 2011, Athens, Greece
SP  - 1421
EP  - 1424
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - GEN
A1  - Burgeth, Bernhard
A1  - Kleefeld, Andreas
A1  - Naegel, Benoît
A1  - Perret, Benjamin
T1  - Editorial — Special Issue: ISMM 2019
T2  - Mathematical Morphology - Theory and Applications
N2  - This editorial presents the Special Issue dedicated to the conference ISMM 2019 and summarizes the articles published in this Special Issue.
Y1  - 2020
U6  - https://doi.org/10.1515/mathm-2020-0200
SN  - 2353-3390
VL  - 4
IS  - 1
SP  - 159
EP  - 161
PB  - De Gruyter
CY  - Warschau
ER  - 
TY  - JOUR
A1  - Kleefeld, Andreas
A1  - Zimmermann, M.
ED  - Constanda, Christian
ED  - Bodmann, Bardo E.J.
ED  - Harris, Paul J.
T1  - Computing Elastic Interior Transmission Eigenvalues
JF  - Integral Methods in Science and Engineering
N2  - An alternative method is presented to numerically compute interior elastic transmission eigenvalues for various domains in two dimensions. This is achieved by discretizing the resulting system of boundary integral equations in combination with a nonlinear eigenvalue solver. Numerical results are given to show that this new approach can provide better results than the finite element method when dealing with general domains.
Y1  - 2022
SN  - 978-3-031-07171-3
U6  - https://doi.org/10.1007/978-3-031-07171-3_10
N1  - Corresponding author: Andreas Kleefeld
SP  - 139
EP  - 155
PB  - Birkhäuser
CY  - Cham
ER  - 
TY  - CHAP
A1  - Pieronek, Lukas
A1  - Kleefeld, Andreas
ED  - Constanda, Christian
ED  - Harris, Paul
T1  - The Method of Fundamental Solutions for Computing Interior Transmission Eigenvalues of Inhomogeneous Media
T2  - Integral Methods in Science and Engineering: Analytic Treatment and Numerical Approximations
N2  - The method of fundamental solutions is applied to the approximate computation of interior transmission eigenvalues for a special class of inhomogeneous media in two dimensions. We give a short approximation analysis accompanied with numerical results that clearly prove practical convenience of our alternative approach.
Y1  - 2019
SN  - 978-3-030-16077-7
U6  - https://doi.org/10.1007/978-3-030-16077-7_28
SP  - 353
EP  - 365
PB  - Birkhäuser
CY  - Cham
ER  - 
TY  - GEN
A1  - Nam, J.
A1  - Arora, D.
A1  - Behbahani, Mehdi
A1  - Probst, M.
A1  - Benkowski, R.
A1  - Behr, Marek
A1  - Pasquali, M.
T1  - New computational method in hemolysis analysis for artificial heart pump
T2  - ASAIO Journal
N2  - The MicroMed DeBakey ventricular assist device is an axial flow pump designed for providing long-term support to end-stage heartfailure patients. Previously, we presented computational analysis of the blood pump flow. From the analysis, we were able to identify regions of high shear and recirculating flow that may cause blood damage, for example, deformation and fragmentation of the red blood cell (RBC). This mechanical hemolysis can be predicted using a tensor-based blood damage model that is based on the physical properties of the RBCs, for example, the relaxation time of the RBC membrane. However, an extensive and detailed analysis was complicated by the fact that the previous method predicts hemolysis along a finite number of pathlines traversed by the RBCs, possibly omitting parts of the flow domain. Furthermore, it is computationally expensive and is not easily parallelizable.
Here, we propose a new method to estimate hemolysis. The method is based on treating the shape of droplet (tensor) as a field variable, like velocity in the Navier-Stokes system. The governing equation for the RBC shape is treated by least-squares finite element method and the volume conservation of the RBC is augmented by Lagrangian multiplier. Unlike the previous method, the proposed method can visualize areas of high RBC strain that is potentially dangerous for mechanical hemolysis. Also, the amount of plasma-free hemoglobin and, consequently, normalized index of hemolysis can be computed as a byproduct. The method is tested in a simple shear flow for validation and an artery graft flow is chosen to show its potential usefulness. Finally, the method is applied to the blood damage estimation for the pump.
Y1  - 2010
U6  - https://doi.org/10.1097/01.mat.0000369377.65122.a3
N1  - 56th Annual Conference of the American Society for Artificial Internal Organs (ASAIO), May 27 - 29, 2010, Baltimore, Maryland
VL  - 56
IS  - 2
SP  - 98
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - CHAP
A1  - Bremm, Florian
A1  - Blaneck, Patrick Gustav
A1  - Bornheim, Tobias
A1  - Grieger, Niklas
A1  - Bialonski, Stephan
T1  - Detecting Sexism in German Online Newspaper Comments with Open-Source Text Embeddings (Team GDA, GermEval2024 Shared Task 1: GerMS-Detect, Subtasks 1 and 2, Closed Track)
T2  - Proceedings of GermEval 2024 Task 1 GerMS-Detect Workshop on Sexism Detection in German Online News Fora (GerMS-Detect 2024)
N2  - Sexism in online media comments is a pervasive challenge that often manifests subtly, complicating moderation efforts as interpretations of what constitutes sexism can vary among individuals. We study monolingual and multilingual open-source text embeddings to reliably detect sexism and misogyny in Germanlanguage online comments from an Austrian newspaper. We observed classifiers trained on text embeddings to mimic closely the individual judgements of human annotators. Our method showed robust performance in the GermEval 2024 GerMS-Detect Subtask 1 challenge, achieving an average macro F1 score of 0.597 (4th place, as reported on Codabench). It also accurately predicted the distribution of human annotations in GerMS-Detect Subtask 2, with an average Jensen-Shannon distance of 0.301 (2nd place). The computational efficiency of our approach suggests potential for scalable applications across various languages and linguistic contexts.
Y1  - 2024
U6  - https://doi.org/10.48550/arXiv.2403.08592
N1  - GermEval 2024 Task 1 GerMS-Detect Workshop on Sexism Detection in German Online News Fora (GerMS-Detect 2024), September 2024, Vienna, Austria
SP  - 33
EP  - 38
PB  - ACL
CY  - Kerrville
ER  - 
TY  - JOUR
A1  - Murib, Mohammed Sharif
A1  - Yeap, Weng Siang
A1  - Eurlings, Y.
A1  - Grinsven, Bart van
A1  - Boyen, Hans-Gerd
A1  - Conings, Bert
A1  - Michiels, Luc
A1  - Ameloot, Marcel
A1  - Carleer, R.
A1  - Warmer, Johannes
A1  - Kaul, Peter Michael
A1  - Haenen, Ken
A1  - Schöning, Michael Josef
A1  - de Ceuninck, Ward A.
A1  - Wagner, Patrick Hermann
T1  - Heat-transfer based characterization of DNA on synthetic sapphire chips
JF  - Sensors and Actuators B: Chemical
N2  - In this study, we show that synthetic sapphire (Al₂O₃), an established implant material, can also serve as a platform material for biosensors comparable to nanocrystalline diamond. Sapphire chips, beads, and powder were first modified with (3-aminopropyl) triethoxysilane (APTES), followed by succinic anhydride (SA), and finally single-stranded probe DNA was EDC coupled to the functionalized layer. The presence of the APTES-SA layer on sapphire powders was confirmed by thermogravimetric analyis and Fourier-transform infrared spectroscopy. Using planar sapphire chips as substrates and X-ray photoelectron spectroscopy (XPS) as surface-sensitive tool, the sequence of individual layers was analyzed with respect to their chemical state, enabling the quantification of areal densities of the involved molecular units. Fluorescence microscopy was used to demonstrate the hybridization of fluorescently tagged target DNA to the probe DNA, including denaturation- and re-hybridization experiments. Due to its high thermal conductivity, synthetic sapphire is especially suitable as a chip material for the heat-transfer method, which was employed to distinguish complementary- and non-complementary DNA duplexes containing single-nucleotide polymorphisms. These results indicate that it is possible to detect mutations electronically with a chemically resilient and electrically insulating chip material.
Y1  - 2016
U6  - https://doi.org/10.1016/j.snb.2016.02.027
SN  - 0925-4005
VL  - 230
IS  - 230
SP  - 260
EP  - 271
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Ziemons, Karl
A1  - Herzog, Hans
A1  - Bosetti, P.
A1  - Feinendegen, L. E.
T1  - Iterative image reconstruction with weighted pixel contribution to projection elements
JF  - European Journal of Nuclear Medicine
Y1  - 1992
SN  - 1619-7089
N1  - Abstracts of the European Association of Nuclear Medicine Congress 23–26 August 1992 Lisboa, Portugal ; V143-2
VL  - 19
IS  - 8
SP  - 588
EP  - 588
ER  - 
TY  - JOUR
A1  - Bäcker, Matthias
A1  - Raue, Markus
A1  - Schusser, Sebastian
A1  - Jeitner, C.
A1  - Breuer, Lars
A1  - Wagner, P.
A1  - Poghossian, Arshak
A1  - Förster, Arnold
A1  - Mang, Thomas
A1  - Schöning, Michael Josef
T1  - Microfluidic chip with integrated microvalves based on temperature- and pH-responsive hydrogel thin films
JF  - Physica Status Solidi  (a)
N2  - Two types of microvalves based on temperature-responsive poly(N-isopropylacrylamide) (PNIPAAm) and pH-responsive poly(sodium acrylate) (PSA) hydrogel films have been developed and tested. The PNIPAAm and PSA hydrogel films were prepared by means of in situ photopolymerization directly inside the fluidic channel of a microfluidic chip fabricated by combining Si and SU-8 technologies. The swelling/shrinking properties and height changes of the PNIPAAm and PSA films inside the fluidic channel were studied at temperatures of deionized water from 14 to 36 °C and different pH values (pH 3–12) of Titrisol buffer, respectively. Additionally, in separate experiments, the lower critical solution temperature (LCST) of the PNIPAAm hydrogel was investigated by means of a differential scanning calorimetry (DSC) and a surface plasmon resonance (SPR) method. Mass-flow measurements have shown the feasibility of the prepared hydrogel films to work as an on-chip integrated temperature- or pH-responsive microvalve capable to switch the flow channel on/off.
Y1  - 2012
U6  - https://doi.org/10.1002/pssa.201100763
SN  - 1862-6319
VL  - 209
IS  - 5
SP  - 839
EP  - 845
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Bäcker, Matthias
A1  - Kramer, F.
A1  - Huck, Christina
A1  - Poghossian, Arshak
A1  - Bratov, Andrey V.
A1  - Abramova, N.
A1  - Schöning, Michael Josef
T1  - Planar and 3D interdigitated electrodes for biosensing applications: The impact of a dielectric barrier on the sensor properties
JF  - Physica Status Solidi (A) - Applications and Materials Science
N2  - Planar and three-dimensional (3D) interdigitated electrodes (IDE) with electrode digits separated by an insulating barrier of different heights were electrochemically characterized and compared in terms of their sensing properties. Due to the impact of the surface resistance, both types of IDE structures display a non-linear behavior in low-ionic strength solutions. The experimental data were fitted to an electrical equivalent circuit and interpreted taking into account the surface-charge-governed properties. The effect of a charged polyelectrolyte layer electrostatically assembled onto the sensor surface on the surface resistance in solutions with different KCl concentration is studied. In case of the same electrode footprint, 3D-IDEs show a larger cell constant and a higher sensitivity to molecular adsorption than that of planar IDEs. The obtained results demonstrate the potential of 3D-IDEs as a new transducer structure for a direct label-free sensing of charged molecules.
Y1  - 2014
U6  - https://doi.org/10.1002/pssa.201330416
SN  - 1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)
VL  - 211
IS  - 6
SP  - 1357
EP  - 1363
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Kloock, Joachim P.
A1  - Moreno, Lia
A1  - Bratov, Andrey V.
A1  - Huachupoma, S.
A1  - Xu, Jingjuan
A1  - Wagner, Torsten
A1  - Yoshinobu, Tatsuo
A1  - Ermolenko, Y. E.
A1  - Vlasov, Yu  G. G.
A1  - Schöning, Michael Josef
T1  - PLD-prepared cadmium sensors based on chalcogenide glasses —ISFET, LAPS and μISE semiconductor structures
JF  - Sensors and Actuators B: Chemical. 118 (2006), H. 1-2
Y1  - 2006
SN  - 0925-4005
N1  - Eurosensors XIX - Eurosensors XIX - The 19th European Conference on Solid-State Transducers
SP  - 149
EP  - 155
ER  - 
TY  - CHAP
A1  - Richter, Charlotte
A1  - Braunstein, Bjoern
A1  - Stäudle, Benjamin
A1  - Attias, Julia
A1  - Suess, Alexander
A1  - Weber, T.
A1  - Rittweger, Joern
A1  - Green, David A.
A1  - Albracht, Kirsten
T1  - In vivo fascicle length of the gastrocnemius muscle during walking in simulated martian gravity using two different body weight support devices
T2  - 23rd Annual Congress of the European College of Sport Science, Dublin, Irland
Y1  - 2018
ER  - 
TY  - CHAP
A1  - Goldmann, Jan-Peter
A1  - Braunstein, Bjoern
A1  - Heinrich, Kai
A1  - Sanno, Maximilian
A1  - Stäudle, Benjamin
A1  - Ritzdorf, Wolfgang
A1  - Brüggemann, Gert-Peter
A1  - Albracht, Kirsten
T1  - Joint work of the take-off leg during elite high jump
T2  - Proceedings of the 33th International Conference on Biomechanics in Sports (ISBS)
Y1  - 2015
ER  - 
TY  - CHAP
A1  - Kloock, Joachim P.
A1  - Schubert, J.
A1  - Ermelenko, Y.
A1  - Vlasov, Y. G.
A1  - Bratov, Andrey V.
A1  - Schöning, Michael Josef
T1  - Thin-film sensors with chalcogenide glass materials – a general survey
T2  - Biochemical sensing utilisation of micro- and nanotechnologies : Warsaw, [23rd - 26th] November 2005 / ed. by M. Mascini ...
Y1  - 2006
SP  - 92
EP  - 97
CY  - Warsaw
ER  - 
TY  - JOUR
A1  - Ketelhut, Maike
A1  - Göll, Fabian
A1  - Braunstein, Björn
A1  - Albracht, Kirsten
A1  - Abel, Dirk
T1  - Comparison of different training algorithms for the leg extension training with an industrial robot
JF  - Current Directions in Biomedical Engineering
N2  - In the past, different training scenarios have been developed and implemented on robotic research platforms, but no systematic analysis and comparison have been done so far. This paper deals with the comparison of an isokinematic (motion with constant velocity) and an isotonic (motion against constant weight) training algorithm. Both algorithms are designed for a robotic research platform consisting of a 3D force plate and a high payload industrial robot, which allows leg extension training with arbitrary six-dimensional motion trajectories. In the isokinematic as well as the isotonic training algorithm, individual paths are defined i n C artesian s pace by sufficient s upport p oses. I n t he i sotonic t raining s cenario, the trajectory is adapted to the measured force as the robot should only move along the trajectory as long as the force applied by the user exceeds a minimum threshold. In the isotonic training scenario however, the robot’s acceleration is a function of the force applied by the user. To validate these findings, a simulative experiment with a simple linear trajectory is performed. For this purpose, the same force path is applied in both training scenarios. The results illustrate that the algorithms differ in the force dependent trajectory adaption.
KW  - Rehabilitation Technology and Prosthetics
KW  - Surgical Navigation and Robotics
Y1  - 2018
U6  - https://doi.org/10.1515/cdbme-2018-0005
SN  - 2364-5504
VL  - 4
IS  - 1
SP  - 17
EP  - 20
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Ketelhut, Maike
A1  - Brügge, G. M.
A1  - Göll, Fabian
A1  - Braunstein, Bjoern
A1  - Albracht, Kirsten
A1  - Abel, Dirk
T1  - Adaptive iterative learning control of an industrial robot during neuromuscular training
JF  - IFAC PapersOnLine
N2  - To prevent the reduction of muscle mass and loss of strength coming along with the human aging process, regular training with e.g. a leg press is suitable. However, the risk of training-induced injuries requires the continuous monitoring and controlling of the forces applied to the musculoskeletal system as well as the velocity along the motion trajectory and the range of motion. In this paper, an adaptive norm-optimal iterative learning control algorithm to minimize the knee joint loadings during the leg extension training with an industrial robot is proposed. The response of the algorithm is tested in simulation for patients with varus, normal and valgus alignment of the knee and compared to the results of a higher-order iterative learning control algorithm, a robust iterative learning control and a recently proposed conventional norm-optimal iterative learning control algorithm. Although significant improvements in performance are made compared to the conventional norm-optimal iterative learning control algorithm with a small learning factor, for the developed approach as well as the robust iterative learning control algorithm small steady state errors occur.
KW  - Iterative learning control
KW  - Robotic rehabilitation
KW  - Adaptive control
Y1  - 2020
U6  - https://doi.org/10.1016/j.ifacol.2020.12.741
SN  - 2405-8963
VL  - 53
IS  - 2
SP  - 16468
EP  - 16475
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Ketelhut, Maike
A1  - Göll, Fabian
A1  - Braunstein, Bjoern
A1  - Albracht, Kirsten
A1  - Abel, Dirk
T1  - Iterative learning control of an industrial robot for neuromuscular training
T2  - 2019 IEEE Conference on Control Technology and Applications
N2  - Effective training requires high muscle forces potentially leading to training-induced injuries. Thus, continuous monitoring and controlling of the loadings applied to the musculoskeletal system along the motion trajectory is required. In this paper, a norm-optimal iterative learning control algorithm for the robot-assisted training is developed. The algorithm aims at minimizing the external knee joint moment, which is commonly used to quantify the loading of the medial compartment. To estimate the external knee joint moment, a musculoskeletal lower extremity model is implemented in OpenSim and coupled with a model of an industrial robot and a force plate mounted at its end-effector. The algorithm is tested in simulation for patients with varus, normal and valgus alignment of the knee. The results show that the algorithm is able to minimize the external knee joint moment in all three cases and converges after less than seven iterations.
KW  - Knee
KW  - Training
KW  - Load modeling
KW  - Force
KW  - Iterative learning control
Y1  - 2019
SN  - 978-1-7281-2767-5 (ePub)
SN  - 978-1-7281-2766-8 (USB)
SN  - 978-1-7281-2768-2 (PoD)
U6  - https://doi.org/10.1109/CCTA.2019.8920659
N1  - 2019 IEEE Conference on Control Technology and Applications (CCTA) Hong Kong, China, August 19-21, 2019
PB  - IEEE
CY  - New York
ER  - 
TY  - JOUR
A1  - Herssens, Nolan
A1  - Cowburn, James
A1  - Albracht, Kirsten
A1  - Braunstein, Bjoern
A1  - Cazzola, Dario
A1  - Colyer, Steffi
A1  - Minetti, Alberto E.
A1  - Pavei, Gaspare
A1  - Rittweger, Jörn
A1  - Weber, Tobias
A1  - Green, David A.
ED  - Cattaneo, Luigi
T1  - Movement in low gravity environments (MoLo) programme – the MoLo-L.O.O.P. study protocol
JF  - PLOS ONE / Public Library of Science
N2  - Exposure to prolonged periods in microgravity is associated with deconditioning of the musculoskeletal system due to chronic changes in mechanical stimulation. Given astronauts will operate on the Lunar surface for extended periods of time, it is critical to quantify both external (e.g., ground reaction forces) and internal (e.g., joint reaction forces) loads of relevant movements performed during Lunar missions. Such knowledge is key to predict musculoskeletal deconditioning and determine appropriate exercise countermeasures associated with extended exposure to hypogravity.
Y1  - 2022
U6  - https://doi.org/10.1371/journal.pone.0278051
SN  - 1932-6203
VL  - 17
IS  - 11
PB  - Plos
CY  - San Francisco
ER  - 
TY  - CHAP
A1  - Braunstein, Bjoern
A1  - Goldmann, Jan-Peter
A1  - Albracht, Kirsten
A1  - Sanno, Maximilian
A1  - Willwacher, Steffen
A1  - Heinrich, Kai
A1  - Herrmann, Volker
A1  - Brüggemann, Gert-Peter
T1  - Joint specific contribution of mechanical power and work during acceleration and top speed in elite sprinters
T2  - 31 International Conference on Biomechanics in Sports, Taipei, Taiwan, July 07 - July 22, 2013
Y1  - 2013
SN  - 1999-4168
ER  -