TY - JOUR A1 - Keutmann, Sabine A1 - Staat, Manfred A1 - Laack, Walter van T1 - Untersuchung der thermischen Auswirkung von therapeutischem Ultraschall N2 - Zusammenfassung: In der Orthopädie zählt der therapeutische Ultraschall als Mittel zur Prävention und Therapiebegleitung. Er hat mechanische, thermische und physiko-chemische Auswirkungen auf den menschlichen Körper. Um mehr Erkenntnisse über die thermischen Auswirkungen zu erlangen, wurden Versuche an einem Hydrogel-Phantom und an Probanden durchgeführt. Dabei entstand eine signifikante Erwärmung des Gewebes, welche beim Probandenversuch an der Oberfläche und beim Hydrogelversuch in der Tiefe gemessen wurde. Summary: In orthopaedics, therapeutic ultrasound is a tool of prevention and therapy support. It has mechanical, thermal and physico-chemical effects on the human body. Tests with a hydrogel phantom and with human probands have been performed in order to obtain more knowledge about their thermal effects. Both tests measured temperature increases in cell tissue, on the surface with the human proband test and in depth with the hydrogel phantom test. T2 - Research about the thermal effects of therapeutic ultrasound Y1 - 2018 SN - 2193-5793 SN - 2193-5785 (Druckausgabe) VL - 7 IS - 10 SP - 518 EP - 522 PB - Deutscher Ärzte-Verl. CY - Köln ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Jannsens, R. A1 - Masri, Y. El. A1 - Michel, C. T1 - Untersuchung der Hochspinzustände in ¹⁷⁸,¹⁸⁰ Os JF - Frühjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft. 11 (1976) Y1 - 1976 N1 - Verhandlungen der Deutschen Physikalischen Gesellschaft ; 1976=6.R.11,8 SP - 950 ER - TY - JOUR A1 - Bialonski, Stephan A1 - Wendler, Martin A1 - Lehnertz, Klaus T1 - Unraveling spurious properties of interaction networks with tailored random networks JF - Plos one N2 - We investigate interaction networks that we derive from multivariate time series with methods frequently employed in diverse scientific fields such as biology, quantitative finance, physics, earth and climate sciences, and the neurosciences. Mimicking experimental situations, we generate time series with finite length and varying frequency content but from independent stochastic processes. Using the correlation coefficient and the maximum cross-correlation, we estimate interdependencies between these time series. With clustering coefficient and average shortest path length, we observe unweighted interaction networks, derived via thresholding the values of interdependence, to possess non-trivial topologies as compared to Erdös-Rényi networks, which would indicate small-world characteristics. These topologies reflect the mostly unavoidable finiteness of the data, which limits the reliability of typically used estimators of signal interdependence. We propose random networks that are tailored to the way interaction networks are derived from empirical data. Through an exemplary investigation of multichannel electroencephalographic recordings of epileptic seizures – known for their complex spatial and temporal dynamics – we show that such random networks help to distinguish network properties of interdependence structures related to seizure dynamics from those spuriously induced by the applied methods of analysis. Y1 - 2011 U6 - http://dx.doi.org/10.1371/journal.pone.0022826 VL - 6 IS - 8 PB - Plos CY - San Francisco ER - TY - JOUR A1 - Stulpe, Werner T1 - Unitary Operator JF - Compendium of Quantum Physics : concepts, experiments, history and philosophy / Daniel Greenberger ... ed. Y1 - 2009 SN - 978-3-540-70622-9 SP - 807 EP - 809 PB - Springer CY - Berlin ER - TY - JOUR A1 - Reißel, Martin A1 - Lustfeld, H. A1 - Hirschfeld, J. A1 - Steffen, B. T1 - Uniqueness of magnetotomography for fuel cells and fuel cell stacks / Lustfeld, H. ; Hirschfeld, J. ; Reißel, M ; Steffen, B. JF - Journal of Physics A: Mathematical and Theoretical. 42 (2009), H. 495205 Y1 - 2009 SN - 0022-3689 SP - 9 S. ER - TY - JOUR A1 - Schäfer, Horst A1 - Worschech, L. A1 - Ossau, W. A1 - Landwehr, G. T1 - Uniaxiale und planare Verspannung von Störstellenkomplexen in ZnSe/GaAs Schichten Y1 - 1997 N1 - Als Poster vorgelegt auf der Frühjahrstagung der DPG in Münster, 17.-21. März 1997, Verhandl. DPG (VI) 32, HL 11.51 / Physikalisches Institut der Universität Würzburg. ER - TY - JOUR A1 - Seynnes, O. R. A1 - Bojsen-Moller, J. A1 - Albracht, Kirsten A1 - Arndt, A. A1 - Cronin, N. J. A1 - Finni, T. A1 - Magnusson, S. P. T1 - Ultrasound-based testing of tendon mechanical properties: a critical evaluation JF - Journal of Applied Physiology Y1 - 2015 U6 - http://dx.doi.org/10.1152/japplphysiol.00849.2014 SN - 8750-7587 VL - 118 IS - 2 SP - 133 EP - 141 ER - TY - JOUR A1 - Laack, Walter van A1 - Albrecht, T. A1 - Casser, H. R. T1 - Ultraschalltherapie in der Praxis JF - Physikalische Therapie in Theorie und Praxis Y1 - 1987 SN - 0178-9201 VL - 8 IS - 10 SP - 628 EP - 631 ER - TY - JOUR A1 - Laack, Walter van A1 - Albrecht, T. T1 - Ultraschalltherapie in der Praxis JF - ZFA - Zeitschrift für Allgemeinmedizin Y1 - 1987 SN - 0341-9835 VL - 63 IS - 19 SP - 605 EP - 608 ER - TY - JOUR A1 - Schäfer, Horst A1 - Scholl, S. A1 - Waag, A. A1 - Hommel, D. (u.a.) T1 - Two-dimensional Shubnikov–de Haas oscillations in modulation-doped CdTe/CdMnTe quantum-well structures JF - Applied Physics Letters. 62 (1993), H. 23 Y1 - 1993 SP - 3010 EP - 3012 ER - TY - JOUR A1 - Näther, Niko A1 - Rolka, David A1 - Poghossian, Arshak A1 - Koudelka-Hep, M. A1 - Schöning, Michael Josef T1 - Two microcell flow-injection analysis (FIA) platforms for capacitive silicon-based field-effect sensors JF - Electrochimica Acta. 51 (2005), H. 5 Y1 - 2005 SN - 0013-4686 U6 - http://dx.doi.org/10.1016/j.electacta.2005.04.066 SP - 924 EP - 929 ER - TY - JOUR A1 - Streun, M. A1 - Chavan, U. A1 - Lame, H. A1 - Parl, C. A1 - Müller-Veggian, Mattea A1 - Ziemons, Karl T1 - Treating the Gain Non-Uniformity of Multi Channel PMTs by Channel-Specific Trigger Levels JF - 2006 IEEE Nuclear Science Symposium Conference Record, Vol. 2. Y1 - 2006 SN - 1082-3654 SP - 1301 EP - 1304 CY - San Diego, CA ER - TY - JOUR A1 - Mennicken, Max A1 - Peter, Sophia K. A1 - Kaulen, Corinna A1 - Simon, Ulrich A1 - Karthäuser, Silvia T1 - Transport through Redox-Active Ru-Terpyridine Complexes Integrated in Single Nanoparticle Devices JF - The Journal of Physical Chemistry C N2 - Transition metal complexes are electrofunctional molecules due to their high conductivity and their intrinsic switching ability involving a metal-to-ligand charge transfer. Here, a method is presented to contact reliably a few to single redox-active Ru-terpyridine complexes in a CMOS compatible nanodevice and preserve their electrical functionality. Using hybrid materials from 14 nm gold nanoparticles (AuNP) and bis-{4′-[4-(mercaptophenyl)-2,2′:6′,2″-terpyridine]}-ruthenium(II) complexes a device size of 30² nm² inclusive nanoelectrodes is achieved. Moreover, this method bears the opportunity for further downscaling. The Ru-complex AuNP devices show symmetric and asymmetric current versus voltage curves with a hysteretic characteristic in two well separated conductance ranges. By theoretical approximations based on the single-channel Landauer model, the charge transport through the formed double-barrier tunnel junction is thoroughly analyzed and its sensibility to the molecule/metal contact is revealed. It can be verified that tunneling transport through the HOMO is the main transport mechanism while decoherent hopping transport is present to a minor extent. Y1 - 2020 U6 - http://dx.doi.org/10.1021/acs.jpcc.9b11716 SN - 1932-7455 VL - 124 IS - 8 SP - 4881 EP - 4889 PB - ACS Publications CY - Washington, DC ER - TY - JOUR A1 - Reißel, Martin A1 - Bitsch, G. A1 - Mawick, G. A1 - Tokar, G. T1 - Transient FEM Simulation of a Door Closing Process and Application to Fatigue / Bitsch, G. ; Mawick, G. ; Reißel, M. ; Tokar, G. JF - Proceedings of the 20. CAD-FEM Users Meeting, 2002 Y1 - 2002 N1 - 2.11.10 SP - 1 EP - 8 ER - TY - JOUR A1 - Werkhausen, Amelie A1 - Cronin, Neil J. A1 - Albracht, Kirsten A1 - Paulsen, Gøran A1 - Larsen, Askild V. A1 - Bojsen-Møller, Jens A1 - Seynnes, Olivier R. T1 - Training-induced increase in Achilles tendon stiffness affects tendon strain pattern during running JF - PeerJ N2 - Background During the stance phase of running, the elasticity of the Achilles tendon enables the utilisation of elastic energy and allows beneficial contractile conditions for the triceps surae muscles. However, the effect of changes in tendon mechanical properties induced by chronic loading is still poorly understood. We tested the hypothesis that a training-induced increase in Achilles tendon stiffness would result in reduced tendon strain during the stance phase of running, which would reduce fascicle strains in the triceps surae muscles, particularly in the mono-articular soleus. Methods Eleven subjects were assigned to a training group performing isometric singleleg plantarflexion contractions three times per week for ten weeks, and another ten subjects formed a control group. Before and after the training period, Achilles tendon stiffness was estimated, and muscle-tendon mechanics were assessed during running at preferred speed using ultrasonography, kinematics and kinetics. Results Achilles tendon stiffness increased by 18% (P <0:01) in the training group, but the associated reduction in strain seen during isometric contractions was not statistically significant. Tendon elongation during the stance phase of running was similar after training, but tendon recoil was reduced by 30% (P <0:01), while estimated tendon force remained unchanged. Neither gastrocnemius medialis nor soleus fascicle shortening during stance was affected by training. Discussion These results show that a training-induced increase in Achilles tendon stiffness altered tendon behaviour during running. Despite training-induced changes in tendon mechanical properties and recoil behaviour, the data suggest that fascicle shortening patterns were preserved for the running speed that we examined. The asymmetrical changes in tendon strain patterns supports the notion that simple inseries models do not fully explain the mechanical output of the muscle-tendon unit during a complex task like running. KW - Achilles tendon KW - Stiffness KW - Running KW - Tendon properties KW - Architectural gear ratio Y1 - 2019 U6 - http://dx.doi.org/10.7717/peerj.6764 SN - 21678359 PB - Peer CY - London ER - TY - JOUR A1 - Staat, Manfred A1 - Heitzer, M. T1 - Traglastanalyse - ein strukturmechanisches Verfahren zur Beurteilung von gerissenen Bauteilen und Verbindungen JF - Festigkeits- und Bruchverhalten von Fügeverbindungen : 32. Tagung des DVM-Arbeitskreises Bruchvorgänge ; 22. und 23. Februar 2000 in Berlin / Richard, H. A. [Hrsg] Y1 - 2000 N1 - DVM-Bericht 232 SP - 183 EP - 192 PB - Deutscher Verband für Materialforschung und -prüfung CY - Berlin ER - TY - JOUR A1 - Sander, Volker A1 - Fidler, Markus A1 - Klimala, Wojciech T1 - Traffic shaping in aggregate-based networks: implementation and analysis / Fidler, Markus ; Sander, Volker ; Klimala, Wojciech JF - Computer Communications. 28 (2005), H. 3 Y1 - 2005 SN - 0140-3664 SP - 274 EP - 286 ER - TY - JOUR A1 - Gun, Jenny A1 - Gutkin, Vitaly A1 - Lev, Ovadia A1 - Boyen, Hans-Gerd A1 - Saitner, Marc A1 - Wagner, Patrick A1 - Olieslaeger, Marc D´ A1 - Abouzar, Maryam H. A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - Tracing gold nanoparticle charge by electrolyte-insulator-semiconductor devices JF - Journal of Physical Chemistry C. 115 (2011), H. 11 Y1 - 2011 SN - 1932-7455 SP - 4439 EP - 4445 PB - American Cemical Society CY - Washington, DC ER - TY - JOUR A1 - Glück, O. A1 - Schöning, Michael Josef A1 - Lüth, H. A1 - Emons, H. A1 - Hanewinkel, C. A1 - Schumacher, D. A1 - Otto, A. T1 - Trace metal determination with gold microelectrodes fabricated by silicon technology JF - Proceedings of the 11th European Conference on Solid-State Transducers / Eurosensors XI, September 21 - 24, 1997, Warsaw, Poland. [Organised by] Warsaw University of Technology. Vol 2. Y1 - 1997 SN - 83-908335-0-6 N1 - Eurosensors ; (11, 1997, Warszawa) ; Eurosensors - European Conference on Solid-State Transducers ; (11 : ; 1997.09.21-24 : ; Warsaw) SP - 615 EP - 618 PB - Sensor Lab Sp. CY - Warsaw ER - TY - JOUR A1 - Glück, O. A1 - Schöning, Michael Josef A1 - Lüth, H. A1 - Otto, A. A1 - Emons, H. T1 - Trace metal determination by dc resistance changes of microstructured thin gold film electrodes JF - Electrochimica Acta. 44 (1999), H. 21-22 Y1 - 1999 SN - 0013-4686 SP - 3761 EP - 3768 ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Behr, Marek A1 - Nicolai, Mike A1 - Probst, Markus T1 - Towards Shape Optimization for Ventricular Assist Devices Using Parallel Stabilized FEM JF - NIC Symposium 2008 : symposium, 20 - 21 February 2008, Forschungszentrum Jülich ; proceedings / organized by John von Neumann Institute for Computing. Ed. by Gernot Münster; Dietrich Wolf; Manfred Kremer (ed.) Y1 - 2008 SN - 978-3-9810843-5-1 N1 - NIC series ; 39 SP - 325 EP - 332 PB - Forschungszentrum CY - Jülich ER - TY - JOUR A1 - Poghossian, Arshak A1 - Platen, J. A1 - Schöning, Michael Josef T1 - Towards self-aligned nanostructures by means of layerexpansion technique JF - Electrochimica Acta. 51 (2005), H. 5 Y1 - 2005 SN - 0013-4686 SP - 838 EP - 843 ER - TY - JOUR A1 - Breuer, Lars A1 - Pilas, Johanna A1 - Guthmann, Eric A1 - Schöning, Michael Josef A1 - Thoelen, Ronald A1 - Wagner, Torsten T1 - Towards light-addressable flow control: responsive hydrogels with incorporated graphene oxide as laser-driven actuator structures within microfluidic channels JF - Sensor and Actuators B: Chemical Y1 - 2019 U6 - http://dx.doi.org/10.1016/j.snb.2019.02.086 SN - 0925-4005 VL - 288 SP - 579 EP - 585 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Abouzar, Maryam H. A1 - Ingebrandt, Sven A1 - Platen, Johannes A1 - Offenhäusser, Andreas A1 - Poghossian, Arshak ED - Comini, Elisabetta T1 - Towards label-free detection of charged macromolecules using field-effect-based structures : Scaling down from capacitive EIS sensor over ISFET to nano-scale devices JF - Nanostructured materials and hybrid composites for gas sensors and biomedical applications : symposium held April 18-20, 2006, San Francisco , California, U.S.A. Y1 - 2006 SN - 9781558998711 IS - paper 0915-R05-04 SP - 89 EP - 94 ER - TY - JOUR A1 - Molinnus, Denise A1 - Sorich, Maren A1 - Bartz, Alexander A1 - Siegert, Petra A1 - Willenberg, Holger S. A1 - Lisdat, Fred A1 - Poghossian, Arshak A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Towards an adrenaline biosensor based on substrate recycling amplification in combination with an enzyme logic gate JF - Sensors and Actuators B: Chemical N2 - An amperometric biosensor using a substrate recycling principle was realized for the detection of low adrenaline concentrations (1 nM) by measurements in phosphate buffer and Ringer’s solution at pH 6.5 and pH 7.4, respectively. In proof-of-concept experiments, a Boolean logic-gate principle has been applied to develop a digital adrenaline biosensor based on an enzyme AND logic gate. The obtained results demonstrate that the developed digital biosensor is capable for a rapid qualitative determination of the presence/absence of adrenaline in a YES/NO statement. Such digital biosensor could be used in clinical diagnostics for the control of a correct insertion of a catheter in the adrenal veins during adrenal venous-sampling procedure. Y1 - 2016 U6 - http://dx.doi.org/10.1016/j.snb.2016.06.064 SN - 0925-4005 VL - 237 SP - 190 EP - 195 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Berretz, F. A1 - Skorupa, S. A1 - Sander, Volker A1 - Belloum, A. T1 - Towards an actor-driven workflow management system for grids JF - International Symposium on Collaborative Technologies and Systems (CTS), 2010 : 17 - 21 May 2010, Chicago, Illinois, USA / IEEE Y1 - 2010 SN - 978-1-4244-6619-1 SP - 611 EP - 616 PB - IEEE CY - Piscataway, NJ ER - TY - JOUR A1 - Poghossian, Arshak A1 - Werner, Frederik A1 - Buniatyan, V. V. A1 - Wagner, Torsten A1 - Miamoto, K. A1 - Yoshinobu, T. A1 - Schöning, Michael Josef T1 - Towards addressability of light-addressable potentiometric sensors: Shunting effect of non-illuminated region and cross-talk JF - Sensor and Actuators B: Chemical N2 - The LAPS (light-addressable potentiometric sensor) platform is one of the most attractive approaches for chemical and biological sensing with many applications ranging from pH and ion/analyte concentration measurements up to cell metabolism detection and chemical imaging. However, although it is generally accepted that LAPS measurements are spatially resolved, the light-addressability feature of LAPS devices has not been discussed in detail so far. In this work, an extended electrical equivalent-circuit model of the LAPS has been presented, which takes into account possible cross-talk effects due to the capacitive coupling of the non-illuminated region. A shunting effect of the non-illuminated area on the measured photocurrent and addressability of LAPS devices has been studied. It has been shown, that the measured photocurrent will be determined not only by the local interfacial potential in the illuminated region but also by possible interfacial potential changes in the non-illuminated region, yielding cross-talk effects. These findings were supported by the experimental investigations of a penicillin-sensitive multi-spot LAPS and a metal-insulator-semiconductor LAPS as model systems. Y1 - 2017 U6 - http://dx.doi.org/10.1016/j.snb.2017.01.047 SN - 0925-4005 IS - 244 SP - 1071 EP - 1079 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kirchner, Patrick A1 - Oberländer, Jan A1 - Suso, Henri-Pierre A1 - Rysstad, Gunnar A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Towards a wireless sensor system for real-time H2O2 monitoring in aseptic food processes JF - Physica status solidi (a) N2 - A wireless sensor system based on the industrial ZigBee standard for low-rate wireless networking was developed that enables real-time monitoring of gaseous H2O2 during the package sterilization in aseptic food processes. The sensor system consists of a remote unit connected to a calorimetric gas sensor, which was already established in former works, and an external base unit connected to a laptop computer. The remote unit was built up by an XBee radio frequency (RF) module for data communication and a programmable system-on-chip controller to read out the sensor signal and process the sensor data, whereas the base unit is a second XBee RF module. For the rapid H2O2 detection on various locations inside the package that has to be sterilized, a novel read-out strategy of the calorimetric gas sensor was established, wherein the sensor response is measured within the short sterilization time and correlated with the present H2O2 concentration. In an exemplary measurement application in an aseptic filling machinery, the suitability of the new, wireless sensor system was demonstrated, wherein the influence of the gas velocity on the H2O2 distribution inside a package was determined and verified with microbiological tests. KW - calorimetric gas sensor;hydrogen peroxide;wireless sensor system Y1 - 2013 U6 - http://dx.doi.org/10.1002/pssa.201200920 SN - 1862-6319 VL - 210 IS - 5 SP - 877 EP - 883 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Gerhards, M. A1 - Skorupa, S. A1 - Sander, Volker A1 - Pfeiffer, P. A1 - Belloum, A. T1 - Towards a security framework for a WS-HumanTask processor JF - 7th International Conference on Network and Service Management (CNSM), 2011 Paris Y1 - 2011 SN - 978-3-901882-44-9 SP - 1 EP - 5 PB - IEEE CY - New York ER - TY - JOUR A1 - Reisert, Steffen A1 - Geissler, Hanno A1 - Flörke, Rudolf A1 - Näther, Niko A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Towards a multi-sensor system for the evaluation of aseptic processes employing hydrogen peroxide vapour (H2O2) JF - Physica status solidi (a) : applications and material science. 208 (2011), H. 6 Y1 - 2011 SN - 1862-6319 SP - 1351 EP - 1356 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Molinnus, Denise A1 - Drinic, Aleksander A1 - Iken, Heiko A1 - Kröger, Nadja A1 - Zinser, Max A1 - Smeets, Ralf A1 - Köpf, Marius A1 - Kopp, Alexander A1 - Schöning, Michael Josef T1 - Towards a flexible electrochemical biosensor fabricated from biocompatible Bombyx mori silk JF - Biosensors and Bioelectronics Y1 - 2021 U6 - http://dx.doi.org/10.1016/j.bios.2021.113204 SN - 0956-5663 VL - 183 IS - Art. 113204 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Arzdorf, M. A1 - Mulchandani, P. A1 - Chen, W. A1 - Mulchandani, A. T1 - Towards a capacitive enzyme sensor for direct determination of organophosphorus pesticides: Fundamentals studies and aspects of development JF - Sensors. 3 (2003), H. 6 Y1 - 2003 SN - 1424-8220 SP - 119 EP - 127 ER - TY - JOUR A1 - Oberländer, Jan A1 - Bromm, Alexander A1 - Wendeler, Luisa A1 - Iken, Heiko A1 - Palomar Duran, Marlena A1 - Greeff, Anton A1 - Kirchner, Patrick A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Towards a biosensor to monitor the sterilisation efficiency of aseptic filling machines JF - Physica status solidi (a) N2 - Sterilisation processes are compulsory in medicine, pharmacy, and food industries to prevent infections of consumers and microbiological contaminations of products. Monitoring the sterilisation by conventional microbiological methods is time- and lab-consuming. To overcome this problem, in this work a novel biosensor has been proposed. The sensor enables a fast method to evaluate sterilisation processes. By means of thin-film technology the sensor's transducer structures in form of IDEs (interdigitated electrodes) have been fabricated on a silicon substrate. Physical characterisation of the developed sensor was done by AFM, SEM, and profilometry. Impedance analyses were conducted for the electrical characterisation. As microbiological layer spores of B. atrophaeus have been immobilised on the sensing structure; spores of this type are a well-known sterilisation test organism. Impedance measurements at a fixed frequency over time were performed to monitor the immobilisation process. A sterilisation process according to aseptic filling machines was applied to demonstrate the sensor functionality. After both, immobilisation and sterilisation, a change in impedance could successfully be detected. Y1 - 2015 U6 - http://dx.doi.org/10.1002/pssa.201431900 SN - 1862-6319 VL - 212 IS - 6 SP - 1299 EP - 1305 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Arreola, Julio A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Toward an immobilization method for spore-based biosensors in oxidative environment JF - Electrochimica Acta Y1 - 2019 U6 - http://dx.doi.org/10.1016/j.electacta.2019.01.148 VL - 302 SP - 394 EP - 401 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Röhlen, Desiree A1 - Pilas, Johanna A1 - Dahmen, Markus A1 - Keusgen, Michael A1 - Selmer, Thorsten A1 - Schöning, Michael Josef T1 - Toward a Hybrid Biosensor System for Analysis of Organic and Volatile Fatty Acids in Fermentation Processes JF - Frontiers in Chemistry N2 - Monitoring of organic acids (OA) and volatile fatty acids (VFA) is crucial for the control of anaerobic digestion. In case of unstable process conditions, an accumulation of these intermediates occurs. In the present work, two different enzyme-based biosensor arrays are combined and presented for facile electrochemical determination of several process-relevant analytes. Each biosensor utilizes a platinum sensor chip (14 × 14 mm²) with five individual working electrodes. The OA biosensor enables simultaneous measurement of ethanol, formate, d- and l-lactate, based on a bi-enzymatic detection principle. The second VFA biosensor provides an amperometric platform for quantification of acetate and propionate, mediated by oxidation of hydrogen peroxide. The cross-sensitivity of both biosensors toward potential interferents, typically present in fermentation samples, was investigated. The potential for practical application in complex media was successfully demonstrated in spiked sludge samples collected from three different biogas plants. Thereby, the results obtained by both of the biosensors were in good agreement to the applied reference measurements by photometry and gas chromatography, respectively. The proposed hybrid biosensor system was also used for long-term monitoring of a lab-scale biogas reactor (0.01 m³) for a period of 2 months. In combination with typically monitored parameters, such as gas quality, pH and FOS/TAC (volatile organic acids/total anorganic carbonate), the amperometric measurements of OA and VFA concentration could enhance the understanding of ongoing fermentation processes. Y1 - 2018 U6 - http://dx.doi.org/10.3389/fchem.2018.00284 IS - 6 PB - Frontiers CY - Lausanne ER - TY - JOUR A1 - Hirschfeld, J. A. A1 - Lustfeld, H. A1 - Reißel, Martin A1 - Steffen, B. T1 - Tomographic diagnostics of current distributions in a fuel cell stack JF - International Journal of Energy Research Y1 - 2010 SN - 0363-907X VL - 34 IS - 3 SP - 284 EP - 292 ER - TY - JOUR A1 - Bäcker, Matthias A1 - Koch, Claudia A1 - Eiben, Sabine A1 - Geiger, Fania A1 - Eber, Fabian A1 - Gliemann, Hartmut A1 - Poghossian, Arshak A1 - Wege, Christina A1 - Schöning, Michael Josef T1 - Tobacco mosaic virus as enzyme nanocarrier for electrochemical biosensors JF - Sensors and Actuators B: Chemical N2 - The conjunction of (bio-)chemical recognition elements with nanoscale biological building blocks such as virus particles is considered as a very promising strategy for the creation of biohybrids opening novel opportunities for label-free biosensing. This work presents a new approach for the development of biosensors using tobacco mosaic virus (TMV) nanotubes or coat proteins (CPs) as enzyme nanocarriers. Sensor chips combining an array of Pt electrodes loaded with glucose oxidase (GOD)-modified TMV nanotubes or CP aggregates were used for amperometric detection of glucose as a model system for the first time. The presence of TMV nanotubes or CPs on the sensor surface allows binding of a high amount of precisely positioned enzymes without substantial loss of their activity, and may also ensure accessibility of their active centers for analyte molecules. Specific and efficient immobilization of streptavidin-conjugated GOD ([SA]-GOD) complexes on biotinylated TMV nanotubes or CPs was achieved via bioaffinity binding. These layouts were tested in parallel with glucose sensors with adsorptively immobilized [SA]-GOD, as well as [SA]-GOD crosslinked with glutardialdehyde, and came out to exhibit superior sensor performance. The achieved results underline a great potential of an integration of virus/biomolecule hybrids with electronic transducers for future applications in biosensorics and biochips. Y1 - 2017 U6 - http://dx.doi.org/10.1016/j.snb.2016.07.096 SN - 0925-4005 VL - 238 SP - 716 EP - 722 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hugenroth, Kristin A1 - Neidlin, Michael A1 - Engelmann, Ulrich M. A1 - Kaufmann, Tim A. S. A1 - Steinseifer, Ulrich A1 - Heilmann, Torsten T1 - Tipless Transseptal Cannula Concept Combines Improved Hemodynamic Properties and Risk‐Reduced Placement: an In Silico Proof‐of‐Concept JF - Artificial Organs Y1 - 2021 U6 - http://dx.doi.org/10.1111/aor.13964 SN - 1525-1594 IS - Accepted Article PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Streun, M. A1 - Brandenburg, G. A1 - Khodaverdi, M. A1 - Larue, H. A1 - Parl, C. A1 - Ziemons, Karl T1 - Timemark correction for the ClearPET™ scanners JF - 2005 IEEE Nuclear Science Symposium Conference Record, Vol. 4 N2 - The small animal PET scanners developed by the Crystal Clear Collaboration (ClearPETtrade) detect coincidences by analyzing timemarks which are attached to each event. The scanners are able to save complete single list mode data which allows analysis and modification of the timemarks after data acquisition. The timemarks are obtained from the digitally sampled detector pulses by calculating the baseline crossing of the rising edge of the pulse which is approximated as a straight line. But the limited sampling frequency causes a systematic error in the determination of the timemark. This error depends on the phase of the sampling clock at the time of the event. A statistical method that corrects these errors will be presented Y1 - 2006 SN - 1082-3654 SP - 2057 EP - 2060 ER - TY - JOUR A1 - Geier, Christian A1 - Lehnertz, Klaus A1 - Bialonski, Stephan T1 - Time-dependent degree-degree correlations in epileptic brain networks: from assortative to dissortative mixing JF - Frontiers in Human Neuroscience Y1 - 2015 U6 - http://dx.doi.org/10.3389/fnhum.2015.00462 SN - 1662-5161 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Dikta, Gerhard T1 - Time series methods to forecast patent filings JF - Forecasting innovations : methods for predicting numbers of patent filings ; with 71 tables / Peter Hingley ; Marc Nicolas (ed.), Y1 - 2006 SN - 978-3-540-35991-3 U6 - http://dx.doi.org/10.1007/3-540-35992-3_6 N1 - ISBN 3-540-35991-5 SP - 95 EP - 124 PB - Springer CY - Berlin [u.a.] ER - TY - JOUR A1 - Terstegge, Andreas A1 - Flachskampf, F. A. A1 - Franke, A. A1 - Job, F. P. [u.a.] T1 - Three-dimensional reconstruction of cardiac structures from transesophageal echocardiography JF - American journal of cardiac imaging. 9 (1995), H. 2 Y1 - 1995 SN - 0887-7971 SP - 141 EP - 147 ER - TY - JOUR A1 - Reißel, Martin T1 - Three-dimensional eddy-current computation using Krylov subspace methods / Reissel, Martin JF - IMA Journal of Mathematics Applied in Business and Industry. 8 (1997), H. 2 Y1 - 1997 SN - 1471-678X SP - 99 EP - 121 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Lieder, R. M. A1 - Gono, Y. T1 - Three particle-bands in ¹⁹⁵,¹⁹⁷ Tl JF - Annual report 1976 / Institut für Kernphysik Kernforschungsanlage Jülich / Ed. board: A. Fäßler ... Y1 - 1977 SP - 35 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Kirchner, Patrick A1 - Li, B. A1 - Spelthahn, H. A1 - Henkel, H. A1 - Friedrich, P. A1 - Kolstad, J. A1 - Keusgen, M. A1 - Schöning, Michael Josef T1 - Thin-film calorimetric H2O2 gas sensor for the validation of germicidal effectivity in aseptic filling processes JF - Procedia Chemistry. 1 (2009), H. 1 Y1 - 2009 SN - 1876-6196 N1 - Proceedings of the Eurosensors XXIII conference ; Eurosensors 23 SP - 983 EP - 986 ER - TY - JOUR A1 - Kirchner, Patrick A1 - Li, Bin A1 - Spelthahn, Heiko A1 - Henkel, Hartmut A1 - Schneider, Andreas A1 - Friedrich, Peter A1 - Kolstad, Jens A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Thin-film calorimetric H2O2 gas sensor for the validation of germicidal effectivity in aseptic filling processes JF - Sensors and Actuators B: Chemical. 154 (2011), H. 2 Y1 - 2011 SN - 1873-3077 N1 - EUROSENSORS XXIII SP - 257 EP - 263 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Schmidt, C. A1 - Schubert, J. A1 - Zander, W. A1 - Mesters, S. A1 - Kordos, P. A1 - Lüth, H. A1 - Legin, A. A1 - Seleznev, B. A1 - Vlasov, Y. G. T1 - Thin film sensors on the basis of chalcogenide glass materials prepared by pulsed laser deposition technique JF - Sensors and Actuators B. 68 (2000), H. 1-3 Y1 - 2000 SN - 0925-4005 SP - 254 EP - 259 ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Schmidt, C. A1 - Schubert, J. A1 - Zander, W. A1 - Kordos, P. A1 - Lüth, H. A1 - Legin, A. A1 - Seleznev, B. A1 - Vlasov, Y. G. T1 - Thin film sensors on the basis of chalcogenide glass materials prepared by pulsed laser deposition technique JF - Proceedings : The Hague, The Netherlands, September 12 - 15, 1999 / [ed. by M. Bartek]. Vol 1. Y1 - 1999 SN - 90-76699-02-X N1 - Eurosensors ; (13, 1999, 's-Gravenhage) ; Eurosensors ; (13 : ; 1999.09.12-15 : ; The Hague) ; European Conference on Solid-State Transducers ; (13 : ; 1999.09.12-15 : ; The Hague) SP - 847 EP - 850 CY - The Hague, The Netherlands ER - TY - JOUR A1 - Mourzina, Yu.G. A1 - Schöning, Michael Josef A1 - Schubert, J. A1 - Zander, W. A1 - Legin, A. A1 - Vlasov, Y. G. A1 - Lüth, H. T1 - Thin film microsensors for fast heavy metal analysis JF - Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...] Y1 - 2000 SN - 87-89935-50-0 N1 - Eurosensors ; (14, 2000, København) ; Eurosensors ; (14 : ; 2000.08.27-30 : ; Copenhagen) ; European Conference on Solid-State Transducers ; (14 : ; 2000.08.27-30 : ; Copenhagen) SP - 839 EP - 840 PB - MIC, Mikroelektronik Centret CY - Lyngby, Denmark ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Glück, O. A1 - Kordos, P. A1 - Lüth, H. A1 - Emons, H. T1 - Thin film electrodes for trace metal analysis by dc resistance changes JF - Proceedings of SPIE. 3857 (1999) Y1 - 1999 SP - 135 EP - 143 ER -