TY - JOUR A1 - Dachwald, Bernd T1 - Optimal Solar Sail Trajectories for Missions to the Outer Solar System JF - 22nd AIAA Applied Aerodynamics Conference and Exhibit - AIAA/AAS Astrodynamics Specialist Conference and Exhibit - AIAA Guidance, Navigation, and Control Conference and Exhibit - AIAA Modeling and Simulation Technologies Conference and Exhibit - AIAA Atmospheric Flight Mechanics Conference and Exhibit : 16 - 19 August 2004, Providence, Rhode Island / American Institute of Aeronautics and Astronautics. - (AIAA meeting papers on disc ; 2004,14-15) Y1 - 2004 N1 - American Institute of Aeronautics and Astronautics ; AIAA/AAS Astrodynamics Specialist Conference and Exhibit <2004, Providence, RI> ; AIAA paper number: AIAA-2004-5406 PB - American Inst. of Aeronautics and Astronautics CY - Reston, Va. ER - TY - CHAP A1 - Schoutetens, Frederic A1 - Dachwald, Bernd A1 - Heiligers, Jeannette T1 - Optimisation of photon-sail trajectories in the alpha-centauri system using evolutionary neurocontrol T2 - 8th ICATT (International Conference on Astrodynamics Tools and Techniques) 23 - 25 June 2021, Virtual N2 - With the increased interest for interstellar exploration after the discovery of exoplanets and the proposal by Breakthrough Starshot, this paper investigates the optimisation of photon-sail trajectories in Alpha Centauri. The prime objective is to find the optimal steering strategy for a photonic sail to get captured around one of the stars after a minimum-time transfer from Earth. By extending the idea of the Breakthrough Starshot project with a deceleration phase upon arrival, the mission’s scientific yield will be increased. As a secondary objective, transfer trajectories between the stars and orbit-raising manoeuvres to explore the habitable zones of the stars are investigated. All trajectories are optimised for minimum time of flight using the trajectory optimisation software InTrance. Depending on the sail technology, interstellar travel times of 77.6-18,790 years can be achieved, which presents an average improvement of 30% with respect to previous work. Still, significant technological development is required to reach and be captured in the Alpha-Centauri system in less than a century. Therefore, a fly-through mission arguably remains the only option for a first exploratory mission to Alpha Centauri, but the enticing results obtained in this work provide perspective for future long-residence missions to our closest neighbouring star system. Y1 - 2021 N1 - 8th ICATT (International Conference on Astrodynamics Tools and Techniques) 23 - 25 June 2021, Virtual SP - 1 EP - 15 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Seboldt, W. T1 - Optimization of Interplanetary Rendezvous Trajectories for Solar Sailcraft Using a Neurocontroller JF - A collection of technical papers / AIAA Astrodynamics Specialist Conference : Monterey, California, 5 - 8 August 2002. - Vol. 2 Y1 - 2002 SN - 1-56347-549-9 N1 - Astrodynamics Specialist Conference <2002, Monterey, Calif.> American Institute of Aeronautics and Astronautics ; AIAA paper number: AIAA-2002-4989 SP - 1263 EP - 1270 PB - American Institute of Aeronautics and Astronautics CY - Reston, Va. ER - TY - JOUR A1 - Dachwald, Bernd T1 - Optimization of Interplanetary Solar Sailcraft Trajectories Using Evolutionary Neurocontrol JF - Journal of guidance, control, and dynamics. 27 (2004), H. 1 Y1 - 2004 SN - 0162-3192 N1 - 2. ISSN: 0162-3192. - 3. ISSN: 0731-5090 SP - 66 EP - 72 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Ohndorf, A. A1 - Gill, E. T1 - Optimization of low-thrust Earth-Moon transfers using evolutionary neurocontrol / Ohndorf, A. ; Dachwald, B. ; Gill, E. JF - IEEE Congress on Evolutionary Computation, 2009. CEC '09. Y1 - 2009 SN - 978-1-4244-2958-5 SP - 358 EP - 364 ER - TY - CHAP A1 - Jung, Alexander A1 - Staat, Manfred A1 - Müller, Wolfram ED - Onate, E. T1 - Optimization of the flight style in ski jumping T2 - 11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20 - 25, 2014, Barcelona Y1 - 2014 N1 - Das Paper wurde nach der Konferenz überarbeitet. SP - 799 EP - 810 ER - TY - JOUR A1 - Jung, Alexander A1 - Müller, Wolfram A1 - Staat, Manfred T1 - Optimization of the flight technique in ski jumping: the influence of wind Y1 - 2019 U6 - http://dx.doi.org/10.1016/j.jbiomech.2019.03.023 IS - Early view PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Dachwald, Bernd T1 - Optimization of very-low-thrust trajectories using evolutionary neurocontrol JF - Acta Astronautica. 57 (2005), H. 2-8 Y1 - 2005 SN - 0094-5765 SP - 175 EP - 185 ER - TY - JOUR A1 - Dachwald, Bernd T1 - Optimization of very-low-thrust trajectories using evolutionary neurocontrol JF - Acta Astronautica N2 - Searching optimal interplanetary trajectories for low-thrust spacecraft is usually a difficult and time-consuming task that involves much experience and expert knowledge in astrodynamics and optimal control theory. This is because the convergence behavior of traditional local optimizers, which are based on numerical optimal control methods, depends on an adequate initial guess, which is often hard to find, especially for very-low-thrust trajectories that necessitate many revolutions around the sun. The obtained solutions are typically close to the initial guess that is rarely close to the (unknown) global optimum. Within this paper, trajectory optimization problems are attacked from the perspective of artificial intelligence and machine learning. Inspired by natural archetypes, a smart global method for low-thrust trajectory optimization is proposed that fuses artificial neural networks and evolutionary algorithms into so-called evolutionary neurocontrollers. This novel method runs without an initial guess and does not require the attendance of an expert in astrodynamics and optimal control theory. This paper details how evolutionary neurocontrol works and how it could be implemented. The performance of the method is assessed for three different interplanetary missions with a thrust to mass ratio <0.15mN/kg (solar sail and nuclear electric). Y1 - 2005 SN - 1879-2030 VL - 57 IS - 2-8 SP - 175 EP - 185 PB - Elsevier CY - Amsterdam [u.a.] ER - TY - JOUR A1 - Dachwald, Bernd A1 - Carnelli, I. A1 - Vasile, M. T1 - Optimizing low-thrust gravity assist interplanetary trajectories using evolutionary neurocontrollers / I. Carnelli ; B. Dachwald ; M. Vasile JF - IEEE Congress on Evolutionary Computation, 2007 : CEC 2007 ; 25 - 28 September 2007, Singapore Y1 - 2007 SN - 978-1-424-41339-3 N1 - ISBN 10: 1-424-41339-7 ; IEEE Congress on Evolutionary Computation <2007, Singapore> ; Institute of Electrical and Electronics Engineers ; Nebent: CEC 2007 ; Parallel als Online-Ausg. erschienen SP - 965 EP - 972 PB - IEEE Service Center CY - Piscataway, NJ ER - TY - JOUR A1 - Sadykov, Rustam A1 - Digel, Ilya A1 - Temiz Artmann, Aysegül A1 - Porst, Dariusz A1 - Linder, Peter A1 - Kayser, Peter A1 - Artmann, Gerhard A1 - Savitskaya, Irina A1 - Zhubanova, Azhar T1 - Oral lead exposure induces dysbacteriosis in rats JF - Journal of Occupational Health. 51 (2009) (2009), H. 1 Y1 - 2009 SN - 1348-9585 SP - 64 EP - 73 ER - TY - JOUR A1 - Rausch, Valentin A1 - Harbrecht, Andreas A1 - Kahmann, Stephanie Lucina A1 - Fenten, Thomas A1 - Jovanovic, Nebojsa A1 - Hackl, Michael A1 - Müller, Lars P. A1 - Staat, Manfred A1 - Wegmann, Kilian T1 - Osteosynthesis of Phalangeal Fractures: Biomechanical Comparison of Kirschner Wires, Plates, and Compression Screws JF - The Journal of Hand Surgery N2 - Purpose The aim of this study was to compare several osteosynthesis techniques (intramedullary headless compression screws, T-plates, and Kirschner wires) for distal epiphyseal fractures of proximal phalanges in a human cadaveric model. Methods A total of 90 proximal phalanges from 30 specimens (index, ring, and middle fingers) were used for this study. After stripping off all soft tissue, a transverse distal epiphyseal fracture was simulated at the proximal phalanx. The 30 specimens were randomly assigned to 1 fixation technique (30 per technique), either a 3.0-mm intramedullary headless compression screw, locking plate fixation with a 2.0-mm T-plate, or 2 oblique 1.0-mm Kirschner wires. Displacement analysis (bending, distraction, and torsion) was performed using optical tracking of an applied random speckle pattern after osteosynthesis. Biomechanical testing was performed with increasing cyclic loading and with cyclic load to failure using a biaxial torsion-tension testing machine. Results Cannulated intramedullary compression screws showed significantly less displacement at the fracture site in torsional testing. Furthermore, screws were significantly more stable in bending testing. Kirschner wires were significantly less stable than plating or screw fixation in any cyclic load to failure test setup. Conclusions Intramedullary compression screws are a highly stable alternative in the treatment of transverse distal epiphyseal phalangeal fractures. Kirschner wires seem to be inferior regarding displacement properties and primary stability. Clinical relevance Fracture fixation of phalangeal fractures using plate osteosynthesis may have the advantage of a very rigid reduction, but disadvantages such as stiffness owing to the more invasive surgical approach and soft tissue irritation should be taken into account. Headless compression screws represent a minimally invasive choice for fixation with good biomechanical properties. Y1 - 2020 U6 - http://dx.doi.org/10.1016/j.jhsa.2020.04.010 SN - 0363-5023 VL - 45 IS - 10 SP - 987.e1 EP - 987.e8 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Sponagel, Stefan A1 - Baroud, G. A1 - Steffen, T. A1 - Wu, J. T1 - Parameter identification for cement infiltration of osteoporotic bone JF - Poromechanics II : Proceedings of the Second Biot Conference on Poromechanics Grenoble, France 26 - 28 August 2002 / ed. by J.-L. Auriault ... Y1 - 2002 SN - 90-5809-394-8 SP - 55 EP - 58 PB - Balkema CY - Lisse [u.a.] ER - TY - JOUR A1 - Dachwald, Bernd A1 - Mengali, Giovanni A1 - Quarta, Alessandrao A. A1 - Macdonald, Malcolm T1 - Parametric Model and Optimal Control of Solar Sails with Optical Degradation JF - Journal of guidance, control, and dynamics. 29 (2006), H. 5 Y1 - 2006 SN - 0162-3192 N1 - 2. ISSN: 0731-5090 SP - 1170 EP - 1178 ER - TY - JOUR A1 - Spietz, Peter A1 - Spröwitz, Tom A1 - Seefeldt, Patric A1 - Grundmann, Jan Thimo A1 - Jahnke, Rico A1 - Mikschl, Tobias A1 - Mikulz, Eugen A1 - Montenegro, Sergio A1 - Reershemius, Siebo A1 - Renger, Thomas A1 - Ruffer, Michael A1 - Sasaki, Kaname A1 - Sznajder, Maciej A1 - Tóth, Norbert A1 - Ceriotti, Matteo A1 - Dachwald, Bernd A1 - Macdonald, Malcolm A1 - McInnes, Colin A1 - Seboldt, Wolfgang A1 - Quantius, Dominik A1 - Bauer, Waldemar A1 - Wiedemann, Carsten A1 - Grimm, Christian D. A1 - Hercik, David A1 - Ho, Tra-Mi A1 - Lange, Caroline A1 - Schmitz, Nicole T1 - Paths not taken – The Gossamer roadmap’s other options JF - Advances in Space Research KW - Solar sail KW - Small spacecraft KW - DLR-ESTEC GOSSAMER roadmap for solar sailing KW - GOSSAMER-1 Y1 - 2021 U6 - http://dx.doi.org/10.1016/j.asr.2021.01.044 SN - 0273-1177 VL - 67 IS - 9 SP - 2912 EP - 2956 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Bhattarai, Aroj A1 - Staat, Manfred ED - Fernandes, P.R. ED - Tavares, J. M. T1 - Pectopexy to repair vaginal vault prolapse: a finite element approach T2 - Proceedings CMBBE 2018 N2 - The vaginal prolapse after hysterectomy (removal of the uterus) is often associated with the prolapse of the vaginal vault, rectum, bladder, urethra or small bowel. Minimally invasive surgery such as laparoscopic sacrocolpopexy and pectopexy are widely performed for the treatment of the vaginal prolapse with weakly supported vaginal vault after hysterectomy using prosthetic mesh implants to support (or strengthen) lax apical ligaments. Implants of different shape, size and polymers are selected depending on the patient’s anatomy and the surgeon’s preference. In this computational study on pectopexy, DynaMesh®-PRP soft, GYNECARE GYNEMESH® PS Nonabsorbable PROLENE® soft and Ultrapro® are tested in a 3D finite element model of the female pelvic floor. The mesh model is implanted into the extraperitoneal space and sutured to the vaginal stump with a bilateral fixation to the iliopectineal ligament at both sides. Numerical simulations are conducted at rest, after surgery and during Valsalva maneuver with weakened tissues modeled by reduced tissue stiffness. Tissues and prosthetic meshes are modeled as incompressible, isotropic hyperelastic materials. The positions of the organs are calculated with respect to the pubococcygeal line (PCL) for female pelvic floor at rest, after repair and during Valsalva maneuver using the three meshes. Y1 - 2018 N1 - 15th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering and 3rd Conference on Imaging and Visualization. CMBBE 2018. 26-29 March 2018, Lisbon, Portugal ER - TY - JOUR A1 - Vant, Christianne A1 - Staat, Manfred A1 - Baroud, Gamal T1 - Percutaneous Vertebroplasty: A Review of Two Intraoperative Complications JF - Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.) Y1 - 2008 SN - 978-3-540-75408-4 SP - 527 EP - 539 PB - Springer CY - Berlin ER - TY - JOUR A1 - Scholz, Christina A1 - Romagnoli, Daniele A1 - Dachwald, Bernd A1 - Theil, Stephan T1 - Performance analysis of an attitude control system for solar sails using sliding masses JF - Advances in Space Research Y1 - 2011 SN - 0273-1177 VL - 48 IS - 11 SP - 1822 EP - 1835 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Savitskaya, Irina S. A1 - Kistaubayeva, Aida S. A1 - Akimbekov, Nuraly S. A1 - Digel, Ilya A1 - Zhubanova, Azhar A. T1 - Performance of Bio-Composite Carbonized Materials in Probiotic Applications T2 - World Academy of Science, Engineering and Technology International Journal of Biotechnology and Bioengineering Y1 - 2013 VL - 7 IS - 7 SP - 685 EP - 689 ER - TY - CHAP A1 - Dachwald, Bernd A1 - Seboldt, Wolfgang A1 - Häusler, Bernd T1 - Performance requirements for near-term interplanetary solar sailcraft missions T2 - 6th International AAAF Symposium on Space Propulsion: Propulsion for Space Transportation of the XXIst Century N2 - Solar sailcraft provide a wide range of opportunities for high-energy low-cost missions. To date, most mission studies require a rather demanding performance that will not be realized by solar sailcraft of the first generation. However, even with solar sailcraft of moderate performance, scientifically relevant missions are feasible. This is demonstrated with a Near Earth Asteroid sample return mission and various planetary rendezvous missions. Y1 - 2002 N1 - 6th International AAAF Symposium on Space Propulsion: Propulsion for Space Transportation of the XXIst Century, Versailles, France, 14-16 May 2002 ER - TY - JOUR A1 - Amin, Rashid A1 - Temiz Artmann, Aysegül A1 - Artmann, Gerhard A1 - Lazarovici, Philip A1 - Lelkes, Peter I. T1 - Permeability of an In Vitro Model of Blood Brain Barrier (BBB) JF - 13th International Conference on Biomedical Engineering / Lim, Chwee Teck [Ed.] Y1 - 2009 SN - 978-3-540-92841-6 N1 - IFMBE Proceedings ; 23, Track 1 ; ICBME 2008 3–6 December 2008 Singapore SP - 81 EP - 84 ER - TY - JOUR A1 - Kuchler, Timon A1 - Günthner, Roman A1 - Ribeiro, Andrea A1 - Hausinger, Renate A1 - Streese, Lukas A1 - Wöhnl, Anna A1 - Kesseler, Veronika A1 - Negele, Johanna A1 - Assali, Tarek A1 - Carbajo-Lozoya, Javier A1 - Lech, Maciej A1 - Adorjan, Kristina A1 - Stubbe, Hans Christian A1 - Hanssen, Henner A1 - Kotliar, Konstantin A1 - Haller, Berhard A1 - Heemann, Uwe A1 - Schmaderer, Christoph T1 - Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation N2 - Background Post-COVID-19 syndrome (PCS) is a lingering disease with ongoing symptoms such as fatigue and cognitive impairment resulting in a high impact on the daily life of patients. Understanding the pathophysiology of PCS is a public health priority, as it still poses a diagnostic and treatment challenge for physicians. Methods In this prospective observational cohort study, we analyzed the retinal microcirculation using Retinal Vessel Analysis (RVA) in a cohort of patients with PCS and compared it to an age- and gender-matched healthy cohort (n = 41, matched out of n = 204). Measurements and main results PCS patients exhibit persistent endothelial dysfunction (ED), as indicated by significantly lower venular flicker-induced dilation (vFID; 3.42% ± 1.77% vs. 4.64% ± 2.59%; p = 0.02), narrower central retinal artery equivalent (CRAE; 178.1 [167.5–190.2] vs. 189.1 [179.4–197.2], p = 0.01) and lower arteriolar-venular ratio (AVR; (0.84 [0.8–0.9] vs. 0.88 [0.8–0.9], p = 0.007). When combining AVR and vFID, predicted scores reached good ability to discriminate groups (area under the curve: 0.75). Higher PCS severity scores correlated with lower AVR (R = − 0.37 p = 0.017). The association of microvascular changes with PCS severity were amplified in PCS patients exhibiting higher levels of inflammatory parameters. Conclusion Our results demonstrate that prolonged endothelial dysfunction is a hallmark of PCS, and impairments of the microcirculation seem to explain ongoing symptoms in patients. As potential therapies for PCS emerge, RVA parameters may become relevant as clinical biomarkers for diagnosis and therapy management. KW - Endothelial dysfunction KW - Long COVID KW - Post-COVID-19 syndrome KW - retinal microvasculature Y1 - 2023 U6 - http://dx.doi.org/10.1007/s10456-023-09885-6 N1 - Corresponding author: Christoph Schmaderer VL - 26 SP - 547 EP - 563 PB - Springer Nature CY - Dordrecht ER - TY - CHAP A1 - Schartner, Karl-Heinz A1 - Loeb, H. W. A1 - Dachwald, Bernd A1 - Ohndorf, Andreas T1 - Perspectives of electric propulsion for outer planetary and deep space missions T2 - European Planetary Science Congress 2009 N2 - Solar-electric propulsion (SEP) is superior with respect to payload capacity, flight time and flexible launch window to the conventional interplanetary transfer method using chemical propulsion combined with gravity assists. This fact results from the large exhaust velocities of electric low–thrust propulsion and is favourable also for missions to the giant planets, Kuiper-belt objects and even for a heliopause probe (IHP) as shown in three studies by the authors funded by DLR. They dealt with a lander for Europa and a sample return mission from a mainbelt asteroid [1], with the TANDEM mission [2]; the third recent one investigates electric propulsion for the transfer to the edge of the solar system. All studies are based on triple-junction solar arrays, on rf-ion thrusters of the qualified RIT-22 type and they use the intelligent trajectory optimization program InTrance [3]. Y1 - 2009 N1 - European Planetary Science Congress 2009, 13-18 September, Potsdam, Germany SP - 416 EP - 416 ER - TY - JOUR A1 - Arinkin, Vladimir A1 - Digel, Ilya A1 - Porst, Dariusz A1 - Temiz Artmann, Aysegül A1 - Artmann, Gerhard T1 - Phenotyping date palm varieties via leaflet cross-sectional imaging and artificial neural network application JF - BMC bioinformatics N2 - Background True date palms (Phoenix dactylifera L.) are impressive trees and have served as an indispensable source of food for mankind in tropical and subtropical countries for centuries. The aim of this study is to differentiate date palm tree varieties by analysing leaflet cross sections with technical/optical methods and artificial neural networks (ANN). Results Fluorescence microscopy images of leaflet cross sections have been taken from a set of five date palm tree cultivars (Hewlat al Jouf, Khlas, Nabot Soltan, Shishi, Um Raheem). After features extraction from images, the obtained data have been fed in a multilayer perceptron ANN with backpropagation learning algorithm. Conclusions Overall, an accurate result in prediction and differentiation of date palm tree cultivars was achieved with average prediction in tenfold cross-validation is 89.1% and reached 100% in one of the best ANN. Y1 - 2014 U6 - http://dx.doi.org/10.1186/1471-2105-15-55 SN - 1471-2105 VL - 15 IS - 55 SP - 1 EP - 8 ER - TY - JOUR A1 - Heiligers, Jeannette A1 - Schoutetens, Frederic A1 - Dachwald, Bernd T1 - Photon-sail equilibria in the alpha centauri system JF - Journal of Guidance, Control, and Dynamics Y1 - 2021 U6 - http://dx.doi.org/10.2514/1.G005446 SN - 1533-3884 SN - 0731-5090 SN - 0162-3192 VL - 44 IS - 5 SP - 1053 EP - 1061 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Zerlin, Kay A1 - Digel, Ilya A1 - Stadler, Andreas M. T1 - Physical discontinuities at body temperature in human red blood cells / Artmann, GM ; Zerlin, K ; Digel, I ; Stadler, A ; Zaccai, G ; Temiz, AA JF - Tissue Engineering. 13 (2007), H. 7 Y1 - 2007 SN - 1076-3279 N1 - TERMIS-EU Meeting Abstracts London, UK September 4–7, 2007 SP - 1778 EP - 1778 ER - TY - JOUR A1 - Duong, Minh Tuan A1 - Nguyen, Nhu Huynh A1 - Staat, Manfred T1 - Physical response of hyperelastic models for composite materials and soft tissues JF - Asia pacific journal on computational engineering Y1 - 2015 U6 - http://dx.doi.org/10.1186/s40540-015-0015-x SN - 2196-1166 VL - 2 IS - 3 (December 2015) SP - 1 EP - 18 ER - TY - CHAP A1 - Duong, Minh Tuan A1 - Nguyen, Nhu Huynh A1 - Staat, Manfred T1 - Physical response of hyperelastic models for composite materials and soft tissues T2 - Advances in Composite Material Y1 - 2017 SN - 978-1-61896-300-0 (Hardcover), 978-1-61896-299-7 (Paperback) N1 - Chapter 5 PB - Scientific Research Publishing CY - Wuhan ER - TY - JOUR A1 - Savitskaya, I. S. A1 - Kistaubayeva, A. S. A1 - Digel, Ilya A1 - Shokatayeva, D. H. T1 - Physicochemical and Antibacterial Properties of Composite Films Based on Bacterial Cellulose and Chitosan for Wound Dressing Materials JF - Eurasian Chemico-Technological Journal Y1 - 2017 U6 - http://dx.doi.org/10.18321/ectj670 SN - 2522-4867 VL - 19 IS - 3 SP - 255 EP - 264 ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Koshitz, I. N. A1 - Svetlova, O. V. A1 - Zaseeva, M. V. T1 - Physiological principles of hypotensive therapy of open-angle glaucoma during presbyopic period. Part I Initial theoretical presuppositions, hypotheses and facts / Koshitz, I. N. ; Svetlova, O. V. ; Zaseeva, M. V. ; Shuhaev, S. V. ; Makarov, F. N. ; Kotli JF - Glaukoma (2006) Y1 - 2006 N1 - Original in Russisch SP - 35 EP - 53 PB - - ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Koshitz, I. N. A1 - Svetlowa, O. V. A1 - Zaseeva, M. V. T1 - Physiological principles of hypotensive therapy of open-angle glaucoma during presbyopic period. Part II Promising algorithms of practical sparing applications / Koshitz, I. N. ; Svetlova, O. V. ; Zaseeva, M. V. ; Shuhaev, S. V. ; Makarov, F. N. ; Kotliar JF - Glaukoma (2006) Y1 - 2006 N1 - Original in Russisch SP - 51 EP - 70 PB - - ER - TY - JOUR A1 - Stadler, Alexander Maximilian A1 - Garvey, Christopher J. A1 - Embs, Jan Peter A1 - Koza, Michael Marek A1 - Unruh, Tobias A1 - Artmann, Gerhard A1 - Zaccai, Guiseppe T1 - Picosecond dynamics in haemoglobin from different species: A quasielastic neutron scattering study JF - Biochimica et biophysica acta (BBA): General Subjects Y1 - 2014 U6 - http://dx.doi.org/10.1016/j.bbagen.2014.06.007 SN - 1872-8006 (E-Journal); 0304-4165 (Print) VL - 1840 IS - 10 SP - 2989 EP - 2999 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Digel, Ilya A1 - Temiz Artmann, Aysegül A1 - Artmann, Gerhard A1 - Nojima, H. T1 - Plasma cluster ions (PCI) influence on microbial cells viability : [abstract] N2 - Recently, SHARP corporation has developed the world’s first “Plasma Cluster Ions (PCI)” air purification technology, which uses plasma discharge to generate cluster ions. The new plasma cluster device releases into the air positive and negative ions, which are harmless to humans and are able to decompose and deactivate airborne substances by chemical reactions. A lot of phenomenological tests of the PCI air purification technology on microbial cells have been conducted. And, in most cases, it has been shown that PCI demonstrate strongly pronounced killing effect. Although, the particular mechanisms of PCI action are still not evident. We studied variations in resistance to PCI among gram-positive airborne microorganisms, as well as some dose-dependent, spatial, cultural and biochemical properties of PCI action in respect of Staphylococcus spp, Enterococcus spp, Micrococcus spp. KW - Clusterion KW - Raumluft KW - Luftreiniger KW - Plasmacluster ion technology KW - Air purification Y1 - 2003 ER - TY - CHAP A1 - Digel, Ilya A1 - Temiz Artmann, Aysegül A1 - Nojima, H. A1 - Artmann, Gerhard T1 - Plasma-generated cluster ions' effects on indoor microflora : [abstract] N2 - Recently, SHARP corporation has developed the world’s first "Plasma Cluster Ions® (PCI)" air purification technology, which uses plasma discharge to generate cluster ions. The new Plasma Cluster Device releases positive and negative ions into the air, which are harmless to humans and are able to decompose and deactivate airborne substances by chemical reactions. In the past, phenomenological tests on the efficacy of the PCI air purification technology on microbial cells have been conducted. In most cases, it has been shown that PCI demonstrated strongly pronounced killing effects on microorganisms. However, the particular mechanisms of PCI action still have to be uncovered. KW - Clusterion KW - Raumluft KW - Luftreiniger KW - Plasmacluster ion technology KW - Air purification Y1 - 2003 ER - TY - JOUR A1 - Staat, Manfred T1 - Plastic collapse analysis of longitudinally flawed pipes and vessels JF - Nuclear Engineering and Design. 234 (2004), H. 1-3 Y1 - 2004 SN - 0029-5493 SP - 25 EP - 43 ER - TY - JOUR A1 - Staat, Manfred T1 - Plastic collapse analysis of longitudinally flawed pipes and vessels N2 - Improved collapse loads of thick-walled, crack containing pipes and vessels are suggested. Very deep cracks have a residual strength which is better modelled by a global limit load. In all burst tests, the ductility of pressure vessel steels was sufficiently high whereby the burst pressure could be predicted by limit analysis with no need to apply fracture mechanics. The relative prognosis error increases however, for long and deep defects due to uncertainties of geometry and strength data. KW - Druckbehälter KW - Stahl KW - Druckbelastung KW - Druckbeanspruchung KW - Rohr KW - Rohrbruch KW - Druckbehälter KW - Stahl KW - Druckbelastung KW - Druckbeanspruchung KW - Rohrbruch KW - Fehlerstellen KW - pipes KW - vessels KW - load limit KW - burst tests KW - burst pressure KW - flaw Y1 - 2004 ER - TY - JOUR A1 - Arampatzis, Adamantios A1 - Peper, Andreas A1 - Bierbaum, Stefanie A1 - Albracht, Kirsten T1 - Plasticity of human Achilles tendon mechanical and morphological properties in response to cyclic strain JF - Journal of Biomechanics N2 - The purpose of the current study in combination with our previous published data (Arampatzis et al., 2007) was to examine the effects of a controlled modulation of strain magnitude and strain frequency applied to the Achilles tendon on the plasticity of tendon mechanical and morphological properties. Eleven male adults (23.9±2.2 yr) participated in the study. The participants exercised one leg at low magnitude tendon strain (2.97±0.47%), and the other leg at high tendon strain magnitude (4.72±1.08%) of similar frequency (0.5 Hz, 1 s loading, 1 s relaxation) and exercise volume (integral of the plantar flexion moment over time) for 14 weeks, 4 days per week, 5 sets per session. The exercise volume was similar to the intervention of our earlier study (0.17 Hz frequency; 3 s loading, 3 s relaxation) allowing a direct comparison of the results. Before and after the intervention ankle joint moment has been measured by a dynamometer, tendon–aponeurosis elongation by ultrasound and cross-sectional area of the Achilles tendon by magnet resonance images (MRI). We found a decrease in strain at a given tendon force, an increase in tendon–aponeurosis stiffness and tendon elastic modulus of the Achilles tendon only in the leg exercised at high strain magnitude. The cross-sectional area (CSA) of the Achilles tendon did not show any statistically significant (P>0.05) differences to the pre-exercise values in both legs. The results indicate a superior improvement in tendon properties (stiffness, elastic modulus and CSA) at the low frequency (0.17 Hz) compared to the high strain frequency (0.5 Hz) protocol. These findings provide evidence that the strain magnitude applied to the Achilles tendon should exceed the value, which occurs during habitual activities to trigger adaptational effects and that higher tendon strain duration per contraction leads to superior tendon adaptational responses. Y1 - 2010 U6 - http://dx.doi.org/10.1016/j.jbiomech.2010.08.014 SN - 0021-9290 VL - 43 IS - 16 SP - 3073 EP - 3079 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Arampatzis, Adamantios A1 - Karamanidis, Kiros A1 - Mademli, Lida A1 - Albracht, Kirsten T1 - Plasticity of the human tendon to short and long-term mechanical loading JF - Exercise and Sport Sciences Reviews Y1 - 2009 U6 - http://dx.doi.org/10.1097/JES.0b013e31819c2e1d SN - 1538-3008 VL - 37 IS - 2 SP - 66 EP - 72 ER - TY - JOUR A1 - Michael, Hackl A1 - Mayer, Katharina A1 - Weber, Mareike A1 - Staat, Manfred A1 - van Riet, Roger A1 - Burkhart, Klau Josef A1 - Müller, Lars Peter A1 - Wegmann, Kilian T1 - Plate osteosynthesis of proximal ulna fractures : a biomechanical micromotion analysis JF - The journal of hand surgery Y1 - 2017 U6 - http://dx.doi.org/10.1016/j.jhsa.2017.05.014 SN - 0363-5023 VL - 42 IS - 10 SP - 834.e1 EP - 834.e7 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Maggakis-Kelemen, Christina A1 - Digel, Ilya A1 - Artmann, Gerhard T1 - Polystyrene sulfonate/Polyallylamine hydrochloride microcapsules as potential artificial red blood cells - improvement of capsule flexibility JF - Biomedizinische Technik. 50 (2005), H. Erg.-Bd. 1 Y1 - 2005 SP - 324 EP - 326 ER - TY - JOUR A1 - Ciritsis, Alexander A1 - Horbach, Andreas A1 - Staat, Manfred A1 - Kuhl, Christiane K. A1 - Kraemer, Nils Andreas T1 - Porosity and tissue integration of elastic mesh implants evaluated in vitro and in vivo JF - Journal of Biomedical Materials Research: Part B: Applied Biomaterials N2 - Purpose In vivo, a loss of mesh porosity triggers scar tissue formation and restricts functionality. The purpose of this study was to evaluate the properties and configuration changes as mesh deformation and mesh shrinkage of a soft mesh implant compared with a conventional stiff mesh implant in vitro and in a porcine model. Material and Methods Tensile tests and digital image correlation were used to determine the textile porosity for both mesh types in vitro. A group of three pigs each were treated with magnetic resonance imaging (MRI) visible conventional stiff polyvinylidene fluoride meshes (PVDF) or with soft thermoplastic polyurethane meshes (TPU) (FEG Textiltechnik mbH, Aachen, Germany), respectively. MRI was performed with a pneumoperitoneum at a pressure of 0 and 15 mmHg, which resulted in bulging of the abdomen. The mesh-induced signal voids were semiautomatically segmented and the mesh areas were determined. With the deformations assessed in both mesh types at both pressure conditions, the porosity change of the meshes after 8 weeks of ingrowth was calculated as an indicator of preserved elastic properties. The explanted specimens were examined histologically for the maturity of the scar (collagen I/III ratio). Results In TPU, the in vitro porosity increased constantly, in PVDF, a loss of porosity was observed under mild stresses. In vivo, the mean mesh areas of TPU were 206.8 cm2 (± 5.7 cm2) at 0 mmHg pneumoperitoneum and 274.6 cm2 (± 5.2 cm2) at 15 mmHg; for PVDF the mean areas were 205.5 cm2 (± 8.8 cm2) and 221.5 cm2 (± 11.8 cm2), respectively. The pneumoperitoneum-induced pressure increase resulted in a calculated porosity increase of 8.4% for TPU and of 1.2% for PVDF. The mean collagen I/III ratio was 8.7 (± 0.5) for TPU and 4.7 (± 0.7) for PVDF. Conclusion The elastic properties of TPU mesh implants result in improved tissue integration compared to conventional PVDF meshes, and they adapt more efficiently to the abdominal wall. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 827–833, 2018. Y1 - 2018 U6 - http://dx.doi.org/10.1002/jbm.b.33877 SN - 1552-4981 VL - 106 IS - 2 SP - 827 EP - 833 PB - Wiley CY - New York, NY ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Kozlova, Tatiana V. A1 - Lanzl, Ines M. T1 - Postoperative aqueous outflow in the human eye after glaucoma filtration surgery: biofluidmechanical considerations JF - Biomedizinische Technik = Biomedical Engineering Y1 - 2009 SN - 1862-278X VL - 54 IS - 1 SP - 14 EP - 22 PB - - ER - TY - JOUR A1 - Jayaraman, Chandrasekaran A1 - Mummidisetty, Chaitanya Krishna A1 - Loesch, Alexandra A1 - Kaur, Sandi A1 - Hoppe-Ludwig, Shenan A1 - Staat, Manfred A1 - Jayaraman, Arun T1 - Postural and metabolic benefits of using a forearm support walker in older adults with impairments JF - Archives of Physical Medicine and Rehabilitation Y1 - 2019 U6 - http://dx.doi.org/10.1016/j.apmr.2018.10.001 SN - 0003-9993 VL - Volume 100 IS - Issue 4 SP - 638 EP - 647 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Dachwald, Bernd A1 - Baturkin, Volodymyr A1 - Coverstone, Victoria L. A1 - Dietrich, Benjamin A1 - Garbe, Gregory P. A1 - Görlich, Marianne A1 - Leipold, Manfred A1 - Lura, Franz A1 - Macdonald, Malcolm A1 - McInnes, Colin R. A1 - Mengali, Giovanni A1 - Quatra, Alessandro A. A1 - Rios-Reyes, Leonel A1 - Scheeres, Daniel J. A1 - Seboldt, Wolfgang A1 - Wie, Bong T1 - Potential Effects of Optical Solar Sail Degradation on Interplanetary Trajectory Design JF - Astrodynamics 2005 : proceedings of the AAS/AIAA astrodynamics conference held August 7 - 11, 2005, South Lake Tahoe, California / ed. by Bobby G. Williams. - Pt. 3. - (Advances in the astronautical sciences ; 123,3) Y1 - 2006 UR - http://www.spacesailing.net/paper/200508_LakeTahoe_Dachwald+.pdf SN - 0-87703-527-X N1 - Astrodynamics Conference <2005, South Lake Tahoe, Calif.> ; American Astronautical Society ; Number: AAS-05-413 SP - 2569 EP - 2592 PB - Univelt CY - San Diego, Calif. ER - TY - CHAP A1 - Dachwald, Bernd A1 - Baturkin, Volodymyr A1 - Coverstone, Victoria A1 - Diedrich, Ben A1 - Garbe, Gregory A1 - Görlich, Marianne A1 - Leipold, Manfred A1 - Lura, Franz A1 - Macdonald, Malcolm A1 - McInnes, Colin A1 - Mengali, Giovanni A1 - Quarta, Alessandro A1 - Rios-Reyes, Leonel A1 - Scheeres, Daniel J. A1 - Seboldt, Wolfgang A1 - Wie, Bong T1 - Potential effects of optical solar sail degredation on trajectory design T2 - AAS/AIAA Astrodynamics Specialist N2 - The optical properties of the thin metalized polymer films that are projected for solar sails are assumed to be affected by the erosive effects of the space environment. Their degradation behavior in the real space environment, however, is to a considerable degree indefinite, because initial ground test results are controversial and relevant inspace tests have not been made so far. The standard optical solar sail models that are currently used for trajectory design do not take optical degradation into account, hence its potential effects on trajectory design have not been investigated so far. Nevertheless, optical degradation is important for high-fidelity solar sail mission design, because it decreases both the magnitude of the solar radiation pressure force acting on the sail and also the sail control authority. Therefore, we propose a simple parametric optical solar sail degradation model that describes the variation of the sail film’s optical coefficients with time, depending on the sail film’s environmental history, i.e., the radiation dose. The primary intention of our model is not to describe the exact behavior of specific film-coating combinations in the real space environment, but to provide a more general parametric framework for describing the general optical degradation behavior of solar sails. Using our model, the effects of different optical degradation behaviors on trajectory design are investigated for various exemplary missions. Y1 - 2005 N1 - 2005 AAS/AIAA Astrodynamics Specialist Conference, 7-11.08.2005. Lake Tahoe, California https://www.space-flight.org/AAS_meetings/2005_astro/2005_astro.html SP - 1 EP - 23 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Seboldt, Wolfgang A1 - Macdonald, Malcolm A1 - Mengali, Giovanni A1 - Quatra, Alessandro A. A1 - McInnes, Colin R. A1 - Rios-Reyes, Leonel A1 - Scheerers, Daniel J. A1 - Wie, Bong A1 - Görlich, Marianne A1 - Lura, Franz A1 - Diedrich, Benjamin A1 - Baturkin, Volodymyr A1 - Coverstone, Victoria L. A1 - Leipold, Manfred A1 - Garbe, Gregory P. T1 - Potential Solar Sail Degradation Effects on Trajectory and Attitude Control JF - AIAA Guidance, Navigation and Control Conference and Exhibit - AIAA Modeling and Simulation Technologies Conference and Exhibit - AIAA Atmospheric Flight Mechanics Conference and Exhibit : [San Francisco, California, 15 - 18 August 2005 ; papers]. - (AIAA meeting papers on disc ; [10.]2005,16-17) Y1 - 2005 SN - 1-56347-765-3 N1 - American Institute of Aeronautics and Astronautics ; AIAA Guidance, Navigation, and Control Conference and Exhibit <2005, San Francisco, Calif.> ; AIAA paper number: AIAA-2006-6172 Link "https://arc.aiaa.org/doi/book/10.2514/MGNC05" am 15.07.2022 nachgetragen Behr PB - American Institute of Aeronautics and Astronautics CY - Reston, Va. ER - TY - JOUR A1 - Savitskaya, Irina A1 - Zhantlessova, Sirina A1 - Kistaubayeva, Aida A1 - Ignatova, Ludmila A1 - Shokatayeva, Dina A1 - Sinyavsky, Yuriy A1 - Kushugulova, Almagul A1 - Digel, Ilya T1 - Prebiotic cellulose–pullulan matrix as a “vehicle” for probiotic biofilm delivery to the host large intestine JF - Polymers N2 - This study describes the development of a new combined polysaccharide-matrix-based technology for the immobilization of Lactobacillus rhamnosus GG (LGG) bacteria in biofilm form. The new composition allows for delivering the bacteria to the digestive tract in a manner that improves their robustness compared with planktonic cells and released biofilm cells. Granules consisting of a polysaccharide matrix with probiotic biofilms (PMPB) with high cell density (>9 log CFU/g) were obtained by immobilization in the optimized nutrient medium. Successful probiotic loading was confirmed by fluorescence microscopy and scanning electron microscopy. The developed prebiotic polysaccharide matrix significantly enhanced LGG viability under acidic (pH 2.0) and bile salt (0.3%) stress conditions. Enzymatic extract of feces, mimicking colon fluid in terms of cellulase activity, was used to evaluate the intestinal release of probiotics. PMPB granules showed the ability to gradually release a large number of viable LGG cells in the model colon fluid. In vivo, the oral administration of PMPB granules in rats resulted in the successful release of probiotics in the colon environment. The biofilm-forming incubation method of immobilization on a complex polysaccharide matrix tested in this study has shown high efficacy and promising potential for the development of innovative biotechnologies. KW - immobilization KW - prebiotic KW - bacterial cellulose KW - biofilms KW - Lactobacillus rhamnosus GG Y1 - 2023 U6 - http://dx.doi.org/10.3390/polym16010030 N1 - This article belongs to the Section "Polymer Composites and Nanocomposites" IS - 16(1) PB - MDPI CY - Basel ER - TY - JOUR A1 - Kezerashvili, Roman Ya A1 - Dachwald, Bernd T1 - Preface: Solar sailing: Concepts, technology, and missions II JF - Advances in Space Research Y1 - 2021 U6 - http://dx.doi.org/10.1016/j.asr.2021.01.037 SN - 0273-1177 VL - 67 IS - 9 SP - 2559 EP - 2560 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Knott, Thomas C. A1 - Sofronia, Raluca E. A1 - Gerressen, Marcus A1 - Law, Yuen A1 - Davidescu, Arjana A1 - Savii, George G. A1 - Gatzweiler, Karl-Heinz A1 - Staat, Manfred A1 - Kuhlen, Torsten W. T1 - Preliminary bone sawing model for a virtual reality-based training simulator of bilateral sagittal split osteotomy T2 - Biomedical simulation : 6th International Symposium, ISBMS 2014, Strasbourg, France, October 16-17, 2014 : proceedings (Lecture notes in computer science : vol. 8789) N2 - Successful bone sawing requires a high level of skill and experience, which could be gained by the use of Virtual Reality-based simulators. A key aspect of these medical simulators is realistic force feedback. The aim of this paper is to model the bone sawing process in order to develop a valid training simulator for the bilateral sagittal split osteotomy, the most often applied corrective surgery in case of a malposition of the mandible. Bone samples from a human cadaveric mandible were tested using a designed experimental system. Image processing and statistical analysis were used for the selection of four models for the bone sawing process. The results revealed a polynomial dependency between the material removal rate and the applied force. Differences between the three segments of the osteotomy line and between the cortical and cancellous bone were highlighted. KW - Bone sawing KW - virtual reality KW - training simulator Y1 - 2014 SN - 978-3-319-12057-7 (Online) SN - 978-3-319-12056-0 (Print) U6 - http://dx.doi.org/10.1007/978-3-319-12057-7_1 SP - 1 EP - 10 PB - Springer CY - Cham ER - TY - CHAP A1 - Peloni, A. A1 - Ceriotti, M. A1 - Dachwald, Bernd T1 - Preliminary trajectory design of a multiple NEO rendezvous mission through solar sailing T2 - Proceedings of the International Astronautical Congress, IAC, Vol. 8, 2014 Y1 - 2015 SN - 978-1-63439-986-9 SP - 5352 EP - 5366 PB - Curran CY - Red Hook, NY ER -