TY - JOUR A1 - Pohl, Martina A1 - Siegert, Petra A1 - Mesch, K. A1 - Bruhn, H. A1 - Grötzinger, Joachim T1 - Active site mutants of pyruvate decarboxylase from Zymomonas mobilis : a site-directed mutagenesis study of L112, I472, I476, E473 and N482 JF - European journal of biochemistry Y1 - 1998 SN - 1432-1033 (E-Journal); 1742-4658 (E-Journal); 0014-2956 (Print); 1742-464X (Print) VL - Vol. 257 IS - Iss. 3 SP - 538 EP - 546 ER - TY - JOUR A1 - Seibler, Jost A1 - Schübeler, Dirk A1 - Fiering, Steven A1 - Groudine, Mark A1 - Bode, Jürgen T1 - DNA cassette exchange in ES cells mediated by Flp recombinase: an efficient strategy for repeated modification of tagged loci by marker-free constructs JF - Biochemistry Y1 - 1998 U6 - https://doi.org/10.1021/bi980288t SN - 1520-4995 VL - 37 IS - 18 SP - 6229 EP - 6234 ER - TY - JOUR A1 - Bode, J. A1 - Bartsch, J. A1 - Boulikas, T. A1 - Iber, M. A1 - Mielke, C. A1 - Schübeler, D. A1 - Seibler, Jost A1 - Benham, C. T1 - Transcription-promoting genomic sites in mammalia: their elucidation and architectural principles JF - Gene therapy & molecular biology Y1 - 1998 SN - 1529-9120 VL - 1 IS - 1 SP - 1 EP - 29 ER - TY - JOUR A1 - Iber, Michaela A1 - Schübeler, Dirk A1 - Seibler, Jost A1 - Höxter, Maria A1 - Bode, Jürgen T1 - Efficient FACS selection procedure for cells undergoing Flp-mediated site-specific conversions JF - Technical Tips Online Y1 - 1998 U6 - https://doi.org/10.1016/S1366-2120(08)70132-6 VL - 4 IS - 1 SP - 25 EP - 29 ER - TY - JOUR A1 - Stulpe, Werner A1 - Bugajski, S. A1 - Hellwig, K.-E. T1 - On Fuzzy Random Variables and Statistical Maps. Bugajski, S.; Hellwig, K.-E.; Stulpe, W. JF - Reports on Mathematical Physics. 41 (1998), H. 1 Y1 - 1998 SN - 0034-4877 SP - 1 EP - 11 ER - TY - JOUR A1 - Wolf, Martin R. A1 - Simon, S. A1 - Schlick, Christopher T1 - Qualitative and Quantitative Analysis of Cooperation / Wolf, M. ; Simon, S. ; Schlick, C. JF - Proceedings : May 26 - 29, 1998, Cannes (France) = Actes : 26 - 29 mai 1998 / INRIA, Institut National de Recherche en Informatique et en Automatique, Unité de recherche ... F. Darses ..., eds Y1 - 1998 N1 - COOP ; Institut National de Recherche en Informatique et en Automatique ; Centre ; (Sophia Antipolis) ; International Conference on the Design of Cooperative Systems ; (3 ; 1998.05.26-29 ; Cannes) ; Conference Internationale sur la Conception de Systèmes Coopératifs ; (3 ; 1998.05.26-29 ; Cannes) ; COOP ; (3 ; 1998.05.26-29 ; Cannes) SP - 1 EP - 5 PB - - CY - Cannes ER - TY - JOUR A1 - Fabo, Sabine T1 - Exhibition review: Documenta X and its media concept JF - Leonardo Y1 - 1998 SN - 0024-094x N1 - Documenta <10, 1997, Kassel> VL - 31 IS - 4 SP - 330 ER - TY - JOUR A1 - Stulpe, Werner A1 - Ruch, Ernst T1 - Proof of the Mixing Theorem for Statistical Systems in Classical Physics. Ruch, Ernst; Stulpe, Werner JF - Acta Applicandae Mathematicae. 53 (1998), H. 3 Y1 - 1998 SN - 1572-9036 SP - 329 EP - 352 ER - TY - JOUR A1 - Zientz, Evelyn A1 - Bongaerts, Johannes A1 - Unden, Gottfried T1 - Fumarate regulation of gene expression in Escherichia coli by the DcuSR (dcuSR genes) two-component regulatory system JF - Journal of bacteriology Y1 - 1998 SN - 1098-5530 (E-Journal); 0021-9193 (Print) VL - Vol. 180 IS - No. 20 SP - 5421 EP - 5425 ER - TY - JOUR A1 - Stulpe, Werner T1 - On the Representation of Quantum Mechanics on a Classical Sample Space JF - International Journal of Theoretical Physics. 37 (1998), H. 1 Y1 - 1998 SN - 1572-9575 SP - 349 EP - 356 ER - TY - JOUR A1 - Kämper, Klaus-Peter A1 - Döpper, J. A1 - Clemens, M. A1 - Ehrfeld, W. T1 - Micro gear pumps for dosing of viscous fluids. / Döpper, J. (u.a.) JF - Journal of Micromechanics and Microengineering. 7 (1997), H. 3 Y1 - 1997 SN - 0960-1317 SP - 230 EP - 232 ER - TY - JOUR A1 - Fredebeul-Krein, Markus T1 - Telecommunications and WTO discipline : an assessment of the WTO agreement on telecommunication services JF - Telecommunications policy. 21 (1997), H. 6 Y1 - 1997 SN - 0308-5961 SP - 477 EP - 491 ER - TY - JOUR A1 - Gebhardt, Michael A1 - Jarke, Matthias A1 - Jacobs, Stephan T1 - A Toolkit for Negotiation Support Interfaces to Multidimensional Data JF - SIGMOD 1997 : proceedings ACM SIGMOD International Conference on Management of Data, May 13 - 15, 1997, Tucson, Arizona, USA / ed. by Joan M. Peckman Y1 - 1997 SN - 0897919114 N1 - International Conference on Management of Data ; (1997, Tucson, Ariz.) PB - ACM Press CY - New York, NY ER - TY - JOUR A1 - Artmann, Gerhard A1 - Sung, K.-L. Paul A1 - Horn, Thomas A1 - Whittemore, Darren [u.a.] T1 - Micropipette aspiration of human erythrocytes induces echinocytes via membrane phospholipid translocation. Artmann, Gerhard Michael; Sung, K.-L. Paul; Horn, Thomas; Whittemore, Darren; Norwich, Gerald; Chien, Shu JF - Biophysical journal. 72 (1997), H. 3 Y1 - 1997 SN - 1542-0086 SP - 1434 EP - 1441 ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Ronkel, F. A1 - Crott, M. A1 - Thust, M. (u.a.) T1 - Miniaturization of potentiometric sensors using porous silicon microtechnology JF - Electrochimica Acta. 42 (1997), H. 22 Y1 - 1997 SN - 0013-4686 SP - 3185 EP - 3193 ER - TY - JOUR A1 - Wittmann, Klaus A1 - Ulamec, S. A1 - Feuerbacher, B. A1 - Rosenbauer, H. (u.a.) T1 - Rosetta Lander - In Situ Investigation of a Cometary Nucleus JF - Lunar and Planetary Science. 28 (1997) Y1 - 1997 SN - 0270-9511 N1 - Proceedings of the 28th Annual Lunar and Planetary Science Conference, March 17-21, 1997, Houston, Texas SP - 1461 EP - 1462 ER - TY - JOUR A1 - Schäfer, Horst A1 - Worschech, L. A1 - Ossau, W. A1 - Fischer, C. T1 - Characterization of structural defects in MBE grown ZnSe JF - Materials Science and Engineering B. 43 (1997), H. 1-3 Y1 - 1997 SN - 0921-5107 N1 - Beitrag zum EMRS - Spring Meeting, 4.-7.06.1996 Strasbourg SP - 29 EP - 32 ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Schütz, S. A1 - Riemer, A. A1 - Weißbecker, B. A1 - Steffen, A. A1 - Kordos, P. A1 - Lüth, H. A1 - Hummel, Hans E. T1 - A BioFET on the basis of intact insect antennae JF - Proceedings of the 11th European Conference on Solid-State Transducers / Eurosensors XI, September 21 - 24, 1997, Warsaw, Poland. [Organised by] Warsaw University of Technology. Vol 2. Y1 - 1997 SN - 83-908335-0-6 N1 - Eurosensors ; (11, 1997, Warszawa) ; Eurosensors - European Conference on Solid-State Transducers ; (11 : ; 1997.09.21-24 : ; Warsaw) SP - 1461 EP - 1464 PB - Sensor Lab Sp. CY - Warsaw ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Weidenbrück, B. A1 - Thust, M. A1 - Kordos, P. A1 - Lüth, H. T1 - A silicon-based sensor array with capacitive EIS structures JF - Proceedings of the 11th European Conference on Solid-State Transducers / Eurosensors XI, September 21 - 24, 1997, Warsaw, Poland. [Organised by] Warsaw University of Technology. Vol 2. Y1 - 1997 SN - 83-908335-0-6 N1 - Eurosensors ; (11, 1997, Warszawa) ; Eurosensors - European Conference on Solid-State Transducers ; (11 : ; 1997.09.21-24 : ; Warsaw) SP - 871 EP - 874 PB - Sensor Lab Sp. CY - Warsaw ER - TY - JOUR A1 - Glück, O. A1 - Schöning, Michael Josef A1 - Lüth, H. A1 - Emons, H. A1 - Hanewinkel, C. A1 - Schumacher, D. A1 - Otto, A. T1 - Trace metal determination with gold microelectrodes fabricated by silicon technology JF - Proceedings of the 11th European Conference on Solid-State Transducers / Eurosensors XI, September 21 - 24, 1997, Warsaw, Poland. [Organised by] Warsaw University of Technology. Vol 2. Y1 - 1997 SN - 83-908335-0-6 N1 - Eurosensors ; (11, 1997, Warszawa) ; Eurosensors - European Conference on Solid-State Transducers ; (11 : ; 1997.09.21-24 : ; Warsaw) SP - 615 EP - 618 PB - Sensor Lab Sp. CY - Warsaw ER - TY - JOUR A1 - Biener, Ernst A1 - Boyken, P. A1 - Sasse, T. T1 - Integrated dredged material management system of Bremen-Seehausen JF - Sardinia 97 : proceedings ; [13 - 17 October 1997, S. Margherita di Pula - Cagliari, Sardinia, Italy] / Sixth International Landfill Symposium. Ed.: Thomas H. Christensen... - Bd. 5 : Landfill regulations, waste characteristics, landfilling in middle and lower income countries, industrial wastes and monolandfills Y1 - 1997 N1 - International Landfill Symposium <6, 1997, Santa Margherita, Pula> SP - 497 EP - 502 PB - CISA, Environmental Sanitary Engineering Centre CY - Cagliari ER - TY - JOUR A1 - Ackermann, Hans-Josef T1 - Morphing- und Level-of-Detail-Techniken zur Reduzierung des Darstellungsaufwands bei Echtzeit-Sichtsimulationen JF - Digital controls for high resolution display : JESSI Europrojekt No. 3203000, AE-36 ; Abschlußbericht ; Laufzeit u. Berichtszeitraum: 01.01.1995 bis 31.12.1996. Y1 - 1997 CY - Erlangen ER - TY - JOUR A1 - Velraj, R. A1 - Seeniraj, R. V. A1 - Hafner, B. A1 - Faber, Christian A1 - Schwarzer, Klemens T1 - Experimental analysis and numerical modelling of inward solidification on a finned vertical tube for a latent heat storage unit JF - Solar energy. 60 (1997), H. 5 Y1 - 1997 SN - 0038-092X SP - 281 EP - 290 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Colautti, P. A1 - Schröder, M. A1 - Tornielli, G. T1 - Electric field Gradient Effects in TEPS JF - Annual report / Istituto Nazionale di Fisica Nucleare, LNL, Laboratori Nazionali di Legnaro. 1996 (1997) Y1 - 1997 N1 - Nebent.: Annual Report LNL-INFN SP - 253 EP - 254 ER - TY - JOUR A1 - Kämper, Klaus-Peter A1 - Ehrfeld, W. A1 - Döpper, J. A1 - Hessel, V. T1 - Microfluidic components for biological and chemical microreactors. Kämper, K.-P.; Ehrfeld, W.; Döpper, J.; Hessel, V.; Lehr, H.; Löwe, H.; Richter, T.; Wolf, A. JF - Proceedings : an investigation of micro structures, sensors, actuators, machines and robots ; Nagoya, Japan, January 26 - 30, 1997 / IEEE Robotics and Automation Society ... Y1 - 1997 SN - 0-7803-3744-1 N1 - International Workshop on Micro-Electro-Mechanical Systems <10, 1997, Nagoya> SP - 338 EP - 343 PB - IEEE Service Center CY - Piscataway, NJ ER - TY - JOUR A1 - Kämper, Klaus-Peter A1 - Ehrfeld, W. A1 - Hessel, V. A1 - Lacher, M. T1 - Market oriented development and production of microdevices. Ehrfeld, W.; Hessel, V.; Kämper, K.-P.; Lacher, M.; Picard, A.; Schmidt, M.; Schulz, C. JF - Proceedings : 21th International Conference on Microelectronics : MIEL '97 ; Niš, Yugoslavia, 14-17 September 1997. Vol. 1 Y1 - 1997 SN - 0-7803-3664-X SP - 71 EP - 79 PB - IEEE Service Center CY - Piscataway, NJ ER - TY - JOUR A1 - Kämper, Klaus-Peter A1 - Lehr, H. A1 - Ehrfeld, W. A1 - Hagemann, B. T1 - Development of micro and millimotors. Lehr, H.; Ehrfeld, W.; Hagemann, B.; Kämper, K.-P.; Michel, F.; Schulz, C.; Thürigen C. JF - Minimally Invasive Therapy and Allied Technologies. 6 (1997) Y1 - 1997 SN - 1364-5706 ER - TY - JOUR A1 - Schuba, Marko T1 - A Performance Evaluation of Connectionless Overlay Networks for ATM JF - INFOCOM ´97. Sixteenth Annual Joint Conference of the IEEE Computer and Communications Societies. Proceedings Vol. 1 Y1 - 1997 SN - 0-8186-7780-5 N1 - http://www.schuba.fh-aachen.de/papers/97-INFOCOM.pdf SP - 152 EP - 158 ER - TY - JOUR A1 - Schuba, Marko A1 - Reichl, Peter A1 - Hoff, Simon T1 - How to Model Complex Periodic Traffic with TES / Reichl, Peter ; Schuba, Marko ; Hoff, Simon JF - Proc. of 13th United Kingdom Workshop on Performance Engineering, Edinburgh, UK, July 1997 Y1 - 1997 SP - 17/1 EP - 17/11 ER - TY - JOUR A1 - Hartung, Frank A1 - Girod, Bernd T1 - Copyright protection in video delivery networks by watermarking of pre-compressed video / Hartung, Frank ; Girod, Bernd JF - Multimedia Applications, Services and Techniques - EMAST ´97 : Second European Conference Milan, Italy, May 21-23, 1997 Proceedings / Fdida, Serge ; Morganti, Michele Y1 - 1997 N1 - Lecture Notes in Computer Science ; 1242 SP - 423 EP - 436 PB - Springer CY - Berlin ER - TY - JOUR A1 - Temiz Artmann, Aysegül A1 - Baskurt, O. K. A1 - Meiselman, H. J. T1 - Red blood cell aggregation in experimental sepsis . Baskurt, O. K.; Temiz, A.; Meiselman, H. J. JF - Journal of Laboratory and Clinical Medicine. 130 (1997), H. 2 Y1 - 1997 SN - 0022-2143 SP - 183 EP - 190 ER - TY - JOUR A1 - Förster, Arnold A1 - Bertuccio, G. A1 - Pullia, A. T1 - Pixel X-ray detectors in epitaxial gallium arsenide withhigh-energy resolution capabilities (Fano factor experimentaldetermination) / G. Bertuccio ; A. Pullia ; J. Lauter ; A. Förster ... JF - IEEE transactions on nuclear science. 44 (1997), H. 1 Y1 - 1997 SN - 0018-9499 SP - 1 EP - 5 ER - TY - JOUR A1 - Förster, Arnold A1 - Rosenauer, A. A1 - Remmele, T. T1 - Strain determination in mismatched semiconductor heterostructures by the digital analysis of lattice images / A. Rosenauer ; T. Remmele ; U. Fischer ; A. Förster ... JF - Microscopy of semiconducting materials 1997 : proceedings of the Royal Microscopical Society Conference held at Oxford University, 7 - 10 April 1997 / ed. by A. G. Cullis ... - (Conference series / Institute of Physics ; 157) Y1 - 1997 SN - 0-7503-0464-2 N1 - MSM <10, 1997, Oxford> ; Conference on Microscopy of Semiconducting Materials <10, 1997, Oxford> ; Institut of Physics SP - 39 EP - ff. PB - Institute of Physics CY - Bristol [u.a.] ER - TY - JOUR A1 - Förster, Arnold A1 - Kordos, P. A1 - Ruders, F. T1 - Properties of LT MBE GaAs for photomixing up to THz frequencies / P. Kordos ; F. Ruders ; M. Marso ; A. Förster JF - Proceedings : 8 - 11 December 1996, Australian National University, Canberra, Australia / ed.: C. Jagadish Y1 - 1997 SN - 0-7803-3374-8 N1 - Conference on Optoelectronic and Microelectronic Materials and Devices <1996, Canberra> ; IEEE catalog number: 96TH8197 SP - 71 EP - ff. PB - IEEE Service Center CY - Piscataway, NJ ER - TY - JOUR A1 - Förster, Arnold A1 - Schmidt, T. A1 - Haug, R. J. T1 - Spectroscopy of the single-particle states of a quantum-dot molecule / T. Schmidt ; R. J. Haug ; K. v. Klitzing ; A. Förster ... JF - Physical review letters. 78 (1997), H. 8 Y1 - 1997 SN - 0031-9007 N1 - ISSN der E-Ausg.: 1079-7114 SP - 1544 EP - 1547 ER - TY - JOUR A1 - Förster, Arnold A1 - Schmidt, T. A1 - Haug, R. J. T1 - Observation of the local structure of landau bands in a disordered conductor / T. Schmidt ; R. J. Haug ; Vladimir I. Fal'ko ... A. Förster ... JF - Physical review letters. 78 (1997), H. 8 Y1 - 1997 SN - 0031-9007 N1 - ISSN der E-Ausg.: 1079-7114 SP - 1540 EP - 1543 ER - TY - JOUR A1 - Förster, Arnold A1 - Rosenauer, A. A1 - Remmele, T. T1 - Atomic scale strain measurements by the digital analysis of transmission electron microscopic lattice images / A. Rosenauer ; T. Remmele ; D. Gerthsen ... A. Förster JF - Optik : international journal for light and electron optics. 105 (1997), H. 3 Y1 - 1997 SN - 0030-4026 SP - 99 EP - 107 ER - TY - JOUR A1 - Förster, Arnold A1 - Lachenmann, S. G. A1 - Kastalsky, A. T1 - Properties of Nb/InAs/Nb hybrid step junctions / S. G. Lachenmann ; A. Kastalsky ; I. Friedrich ; A. Förster ... JF - Journal of low temperature physics. 106 (1997), H. 3-4 Y1 - 1997 SN - 0022-2291 N1 - ISSN der E-Ausg.: 1573-7357 SP - 321 EP - 326 ER - TY - JOUR A1 - Ungermanns, C. A1 - Ahe, M. v. d. A1 - Carius, Reinhard A1 - Förster, Arnold T1 - Optimization of III/V binary growth with RHEED in MOMBE / C. Ungermanns ; M. v. d. Ahe ; R. Carius ; A. Förster ... JF - Fresenius' Journal of Analytical Chemistry. 358 (1997), H. 1-2 Y1 - 1997 SN - 0937-0633 N1 - ISSN der E-Ausg.: 1432-1130 SP - 101 EP - 104 ER - TY - JOUR A1 - Mayer, Claudia T1 - L'Estétique et le pouvoir: Le discours chaotique de l'Allemagne unifiée JF - Canadian review of comparative literature : CRCL = Revue canadienne de littérature comparée : RCLC / Canadian Comparative Literature Association. 24 (1997), H. 2 Y1 - 1997 SN - 0319-051X SP - 297 EP - 317 ER - TY - JOUR A1 - Biselli, Manfred A1 - Schröder, B. A1 - Herfurth, C. A1 - Schmoll, H.-J. T1 - Cocultivation of hematopoietic cells in a fluidized bed reactor / Schröder, B. ; Herfurth, C. ; Biselli, M. ; Schmoll, H.-J. ; Link, H. ; Ebell, W. ; Wandrey, C. JF - Animal cell technology : basic & applied aspects : proceedings of the Eighth Annual Meeting of the Japanese Association for Animal Cell Technology, Iizuka, Fukuoka, Japan, November 6-10, 1995 / edited by K. Funatsu, Y. Shirai, and T. Matsushita Y1 - 1997 SN - 0-7923-4486-3 N1 - Japanese Association for Animal Cell Technology. ; Meeting ; <8 ; 1995 : ; Iizuka-shi, Japan> SP - 137 EP - 141 PB - Kluwer Acad. Press CY - Boston ER - TY - JOUR A1 - Scherer, Ulrich W. A1 - Hör, G. T1 - Artifacts and Pitfalls in FDG-PET Whole-Body Scans / U.W. Scherer, G. Hör JF - Radionuclides for Mammary Gland - Current Status and Future Aspects / G. S. Limouris [Hrsg.] Y1 - 1997 SN - 960-85227-6-5 SP - 37 EP - 42 PB - Mediterra Publishers CY - Athen ER - TY - JOUR A1 - Biselli, Manfred A1 - Noll, T. A1 - Wandrey, C. T1 - On-line biomass monitoring of immobilized hybridoma cells by dielectrical measurements / Noll, T. ; Biselli, M. ; Wandrey, C. JF - Animal cell technology : from vaccines to genetic medicine ; [Vilamoura, Portugal, May 1996] / ed. by Manuel J. T. Carrondo Y1 - 1997 SN - 0-7923-4321-2 SP - 289 EP - 294 PB - Kluwer CY - Dordrecht ER - TY - JOUR A1 - Biselli, Manfred A1 - Schröder, B. A1 - Herfurth, C. A1 - Meißner, P. T1 - Differentiation of bone marrow cells immobilized on microcarriers in a fluidized bed reactor / Schröder, B. ; Herfurth, C. ; Meißner, P. ; Biselli, M. ; Link, H. ; Wandrey, C. JF - Animal cell technology : from vaccines to genetic medicine ; [Vilamoura, Portugal, May 1996] / ed. by Manuel J. T. Carrondo Y1 - 1997 SN - 0-7923-4321-2 SP - 589 EP - 593 PB - Kluwer CY - Dordrecht ER - TY - JOUR A1 - Biselli, Manfred A1 - Zeng, Steffen A1 - Dinter, Andre A1 - Eisenkrätzer, Detlef T1 - Pilot Scale Expression and Purification of Soluble Protein A Tagged β1,6N-Acetylglucosaminyltransferase in CHO Cells / Zeng, Steffen ; Dinter, Andre ; Eisenkrätzer, Detlef ; Biselli, Manfred ; Wandrey, Christian ; Berger, Eric G. JF - Biochemical and Biophysical Research Communications. 237 (1997), H. 3 Y1 - 1997 SN - 0006-291X SP - 653 EP - 658 ER - TY - JOUR A1 - Havermann, Marc A1 - Beylich, A. E. T1 - Performance and Limitations of the Laser-Induced Fluorescence Measurement Technique and the Established Experimental Methods for the Study of Supersonic Mixing / Havermann, M. ; Beylich, A. E. JF - International Journal of heat and technology. 15 (1997), H. 2 Y1 - 1997 SP - 3 EP - 10 PB - - ER - TY - JOUR A1 - Langen, Karl J. A1 - Ziemons, Karl A1 - Kiwit, Jürgen C. W. A1 - Herzog, Hans A1 - Kuwert, Torsten A1 - Bock, Wolfgang A1 - Stöcklin, Gerhard A1 - Feinendegen, Ludwig E. A1 - Müller-Gärtner, Hans-W. T1 - 3-[123I]iodo-α-methyltyrosine and [methyl-11C]-L-methionine uptake in cerebral gliomas: a compara-tive study using SPECT and PET JF - Journal of Nuclear Medicine Y1 - 1997 SN - 0161-5505 VL - 38 IS - 4 SP - 517 EP - 522 ER - TY - JOUR A1 - Weckesser, Matthias A1 - Hufnagel, Andreas A1 - Ziemons, Karl A1 - Grießmeier, Martin A1 - Sonnenberg, Frank A1 - Hackländer, Thomas A1 - Langen, Karl-J. A1 - Holschbach, Markus A1 - Elger, Christian E. A1 - Müller-Gärtner, Hans-W. T1 - Effect of partial volume correction on muscarinic cholinergic receptor imaging with single-photon emission tomography in patients with temporal lobe epilepsy JF - European Journal of Nuclear Medicine N2 - Animal experiments and preliminary results in humans have indicated alterations of hippocampal muscarinic acetylcholine receptors (mAChR) in temporal lobe epilepsy. Patients with temporal lobe epilepsy often present with a reduction in hippocampal volume. The aim of this study was to investigate the influence of hippocampal atrophy on the quantification of mAChR with single photon emission tomography (SPET) in patients with temporal lobe epilepsy. Cerebral uptake of the muscarinic cholinergic antagonist [123I]4-iododexetimide (IDex) was investigated by SPET in patients suffering from temporal lobe epilepsy of unilateral (n=6) or predominantly unilateral (n=1) onset. Regions of interest were drawn on co-registered magnetic resonance images. Hippocampal volume was determined in these regions and was used to correct the SPET results for partial volume effects. A ratio of hippocampal IDex binding on the affected side to that on the unaffected side was used to detect changes in muscarinic cholinergic receptor density. Before partial volume correction a decrease in hippocampal IDex binding on the focus side was found in each patient. After partial volume no convincing differences remained. Our results indicate that the reduction in hippocampal IDex binding in patients with epilepsy is due to a decrease in hippocampal volume rather than to a decrease in receptor concentration. Y1 - 1997 SN - 1619-7089 VL - 24 IS - 9 SP - 1156 EP - 1161 ER - TY - JOUR A1 - Schmidt, Daniela A1 - Langen, Karl-J. A1 - Herzog, Hans A1 - Wirths, Jochen A1 - Holschbach, Markus A1 - Kiwit, Jürgen C. W. A1 - Ziemons, Karl A1 - Coenen, Heinz-H. A1 - Müller-Gärtner, Hans-W. T1 - Whole-body kinetics and dosimetry of L-3[123I]-iodo-α-methyltyrosine JF - European Journal of Nuclear Medicine Y1 - 1997 SN - 1619-7089 VL - 24 IS - 9 SP - 1162 EP - 1166 ER - TY - JOUR A1 - Balewski, J. A1 - Brauksiepe, S. A1 - Hardt, Arno T1 - Threshold measurements at the internal experimental facility COSY-11 / J. Balewski [u.a.] JF - Nuclear physics A. Vol. 626, iss. 1-2 Y1 - 1997 SN - 1873-1554 (E-Journal) ; 0375-9474 (Print) SP - 85 EP - 92 ER -