TY  - JOUR
A1  - Weckesser, Matthias
A1  - Hufnagel, Andreas
A1  - Ziemons, Karl
A1  - Grießmeier, Martin
A1  - Sonnenberg, Frank
A1  - Hackländer, Thomas
A1  - Langen, Karl-J.
A1  - Holschbach, Markus
A1  - Elger, Christian E.
A1  - Müller-Gärtner, Hans-W.
T1  - Effect of partial volume correction on muscarinic cholinergic receptor imaging with single-photon emission tomography in patients with temporal lobe epilepsy
JF  - European Journal of Nuclear Medicine
N2  - Animal experiments and preliminary results in humans have indicated alterations of hippocampal muscarinic acetylcholine receptors (mAChR) in temporal lobe epilepsy. Patients with temporal lobe epilepsy often present with a reduction in hippocampal volume. The aim of this study was to investigate the influence of hippocampal atrophy on the quantification of mAChR with single photon emission tomography (SPET) in patients with temporal lobe epilepsy. Cerebral uptake of the muscarinic cholinergic antagonist [123I]4-iododexetimide (IDex) was investigated by SPET in patients suffering from temporal lobe epilepsy of unilateral (n=6) or predominantly unilateral (n=1) onset. Regions of interest were drawn on co-registered magnetic resonance images. Hippocampal volume was determined in these regions and was used to correct the SPET results for partial volume effects. A ratio of hippocampal IDex binding on the affected side to that on the unaffected side was used to detect changes in muscarinic cholinergic receptor density. Before partial volume correction a decrease in hippocampal IDex binding on the focus side was found in each patient. After partial volume no convincing differences remained. Our results indicate that the reduction in hippocampal IDex binding in patients with epilepsy is due to a decrease in hippocampal volume rather than to a decrease in receptor concentration.
Y1  - 1997
SN  - 1619-7089
VL  - 24
IS  - 9
SP  - 1156
EP  - 1161
ER  - 
TY  - JOUR
A1  - Weckesser, Martin
A1  - Grießmeier, Martin
A1  - Schmidt, Daniela
A1  - Sonnenberg, Frank
A1  - Ziemons, Karl
A1  - Kemna, Lars
A1  - Holschbach, Marcus
A1  - Langen, Karl-J.
A1  - Müller-Gärtner, Hans-W.
T1  - Iodine-123 α-methyl tyrosine single-photon emission tomography of cerebral gliomas: standardised evaluation of tumour uptake and extent
JF  - European Journal of Nuclear Medicine
N2  - Single-photon emission tomography (SPET) with the amino acid analogue l-3-[123I]iodo-α-methyl tyrosine (IMT) is helpful in the diagnosis and monitoring of cerebral gliomas. Radiolabelled amino acids seem to reflect tumour infiltration more specifically than conventional methods like magnetic resonance imaging and computed tomography. Automatic tumour delineation based on maximal tumour uptake may cause an overestimation of mean tumour uptake and an underestimation of tumour extension in tumours with circumscribed peaks. The aim of this study was to develop a program for tumour delineation and calculation of mean tumour uptake which takes into account the mean background activity and is thus optimised to the problem of tumour definition in IMT SPET. Using the frequency distribution of pixel intensities of the tomograms a program was developed which automatically detects a reference brain region and draws an isocontour region around the tumour taking into account mean brain radioactivity. Tumour area and tumour/brain ratios were calculated. A three-compartment phantom was simulated to test the program. The program was applied to IMT SPET studies of 20 patients with cerebral gliomas and was compared to the results of manual analysis by three different investigators. Activity ratios and chamber extension of the phantom were correctly calculated by the automatic analysis. A method based on image maxima alone failed to determine chamber extension correctly. Manual region of interest analysis in patient studies resulted in a mean inter-observer standard deviation of 8.7%±6.1% (range 2.7%–25.0%). The mean value of the results of the manual analysis showed a significant correlation to the results of the automatic analysis (r = 0.91, P<0.0001 for the uptake ratio; r = 0.87, P<0.0001 for the tumour area). We conclude that the algorithm proposed simplifies the calculation of uptake ratios and may be used for observer-independent evaluation of IMT SPET studies. Three-dimensional tumour recognition and transfer to co-registered morphological images based on this program may be useful for the planning of surgical and radiation treatment.
Y1  - 1998
SN  - 1619-7089
VL  - 25
IS  - 2
SP  - 150
EP  - 156
ER  - 
TY  - CHAP
A1  - Weber, S.
A1  - Terstegge, Andreas
A1  - Halling, H.
A1  - Herzog, H.
A1  - Reinartz, R.
A1  - Reinhart, P.
A1  - Rongen, F.
A1  - Müller-Gärtner, H.-W.
T1  - The design of an animal PET: flexible geometry for achieving optimal spatial resolution or high sensitivity
T2  - Conference record / 1995 IEEE Nuclear Science Symposium and Medical Imaging, October 21 - 28, 1995, San Francisco ; vol. 2
Y1  - 1995
SN  - 078033180X ; 0780331818 ; 0780331826
SP  - 1002
EP  - 1005
PB  - IEEE
CY  - Piscataway, NJ
ER  - 
TY  - CHAP
A1  - Weber, S.
A1  - Terstegge, Andreas
A1  - Engels, R.
A1  - Herzog, H.
A1  - Reinartz, R.
A1  - Reinhart, P.
A1  - Rongen, F.
A1  - Müller-Gärtner, H. W.
A1  - Halling, H.
T1  - The KFA TierPET: performance characteristics and measurements
T2  - Conference record / 1996 IEEE Nuclear Science Symposium [and Medical Imaging], November 2 - 9, 1996, Anaheim, California ; vol. 2
Y1  - 1996
SN  - 0-7803-3534-1
SN  - 1082-3654
SP  - 1117
EP  - 1119
PB  - IEEE
CY  - Piscataway, NJ
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Schulte, A.
A1  - Lauterbach, Gerhard
A1  - Südkamp, Michael [u.a.]
T1  - Studienüberblick zu transienten Druckexkursionen bei Membranoxygenatoren / A. Schulte, G. Lauterbach, M. Südkamp, H.-J. Weber
JF  - Kardiotechnik. 8 (1999), H. 1
Y1  - 1999
SN  - 0941-2670
SP  - 14
EP  - 16
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Schmitt, W.
A1  - Jahn, D.
A1  - Euringer, H.
T1  - Ein Versuch zur theoretischen Temperaturermittlung im Schneidbereich bei Bohrungen in kortikalem Knochen - An Experiment to Calculate the Theoretical Temperature at the Drill - Cortical Bone Interface / Schmitt, W. ; Weber, H. J. ; Jahn, D. ; Euringer, H.
JF  - Biomedizinische Technik/Biomedical Engineering. 34 (1989), H. 3
Y1  - 1989
SN  - 0013-5585
N1  - in der Bereichsbibliothek Jülich gedruckt vorhanden
SP  - 53
EP  - 56
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Schmitt, W.
A1  - Jahn, D.
T1  - Thermische Untersuchungen beim Bohren in kortikalem Knochen unter Verwendung verschiedener Kühlsysteme / Schmitt, W. ; Weber, H. J. ; Jahn, D.
JF  - Deutsche zahnärztliche Zeitschrift : DZZ. 43 (1988), H. 7
Y1  - 1988
SN  - 0012-1029
SP  - 802
EP  - 805
ER  - 
TY  - CHAP
A1  - Weber, Hans-Joachim
A1  - Porschen, W.
A1  - Dietzel, F.
A1  - [u.a.], 
ED  - Streffer, Christian
T1  - In vivo analysis of the influence of combined hyperthermia and gamma irradiation on euoxic and hypoxic tumor cells
T2  - Cancer therapy by hyperthermia and radiation : [proceedings of the 2. International Symposium on Cancer Therapy by Hyperthermia and Radiation, Essen, 2.-4.6.1977]
Y1  - 1978
SN  - 0-8067-1701-7
SN  - 3-541-71701-7
SP  - 276
EP  - 277
PB  - Urban and Schwarzenberg
CY  - Baltimore ; Munich [u.a.]
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Mo, Xiumei
A1  - Ramakrishna, S.
T1  - PCL-PGLA composite tubular scaffold preparation and biocompatibility investigation / X. Mo, H.-J. Weber, S. Ramakrishna
JF  - The International journal of artificial organs. 29 (2006), H. 8
Y1  - 2006
SP  - 790
EP  - 799
PB  - -
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Mo, Xiumei
A1  - Chen, Zonggang
T1  - Electrospun nanofibers of collagen-chitosan and P(LLA-CL) for tissue engineering / Mo Xiumei, Chen Zonggang, Hans J. Weber
JF  - Frontiers of materials science in China. 1 (2007), H. 1
Y1  - 2007
SN  - 1673-7377
SP  - 20
EP  - 23
PB  - -
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Mo, Xiumei
T1  - Electrospinning P(LLA-CL) nanofiber: a tubular scaffold fabrication with circumferential alignment / Xiumei Mo, Hans-Joachim Weber
JF  - Contributions from 6th Austrian Polymer Meeting : Vienna, Austria, September 15 - 17, 2003 / Symposium ed.: W. H. Binder
Y1  - 2004
N1  - Österreichische Polymertage <6, 2003, Wien>. - (Macromolecular symposia ; 217,1)
SP  - 413
EP  - 416
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Laco, Filip
A1  - Kun, Ma
A1  - Ramakrishna, S.
T1  - The dose effect of human bone marrow-derived mesenchymal stem cells on epidermal development in organotypic co-culture / Laco, Filip ; Kun, Ma ; Weber, Hans Joachim ; Ramakrishna, S. ; Chan, Casey K.
JF  - Journal of Dermatological Science. 55 (2009), H. 3
Y1  - 2009
SN  - 0923-1811
SP  - 150
EP  - 160
ER  - 
TY  - BOOK
A1  - Weber, Hans-Joachim
A1  - Kaminsky, Radoslav
A1  - Kallweit, Stephan
A1  - Simons, Antoine
T1  - PIV measurements with high temporal resolution behind artificial heart valves
Y1  - 2005
N1  - International Symposium on Particle Image Velocimetry <6, 2005, Pasadena, Calif.>
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Hekmat, Khosro
A1  - Kanani, Reza
A1  - Ahmadpour, R. [u.a.]
T1  - Haben Mobiltelefone einen negativen Einfluss auf moderne Herzschrittmacher? / K. Hekmat, R. Kanani, R. Ahmadpour, G. Lauterbach, M. Südkamp, H.-J. Weber, E. R. de Vivie
JF  - Kardiotechnik. 11 (2002), H. 2
Y1  - 2002
SN  - 0941-2670
SP  - 45
EP  - 47
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Hekmat, K.
A1  - Zimmermann, T.
A1  - Kampe, S.
T1  - Impact of tranexamic acid vs. aprotinin on blood loss and transfusion requirements after cardiopulmonary bypass: a prospective, randomised, double-blind trial / Hekmat, K. ; Zimmermann, T. ; Kampe, S. ; Kasper, S. M. ; Weber, H. J. ; Geissler, H. J. ; Meh
JF  - Current Medical Research and Opinion. 20 (2004), H. 1
Y1  - 2004
SN  - 0300-7995
SP  - 121
EP  - 126
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Bhuju, S.
A1  - Chandra, S.
A1  - Mo, X.
T1  - Fabrication of biodegradable nanofibers for tubular scaffolds in regenerative medicine / Weber, H.-J. ; Bhuju, S. ; Chandra, S. ; Mo, X.
JF  - Biomedizinische Technik. 49 (2004), H. Erg.-Bd. 2, Teil 2
Y1  - 2004
SP  - 1016
EP  - 1017
ER  - 
TY  - BOOK
A1  - Weber, Hans-Joachim
T1  - In-vivo-Untersuchungen am Experimentaltumor Sarkom 180 über die Therapieeffizienz von Gammastrahlen und Neutronen in Verbindung mit Hyperthermie und Misonidazol
Y1  - 1982
N1  - Düsseldorf, Univ., Diss., 1982
ER  - 
TY  - CHAP
A1  - Weber, Hans-Joachim
T1  - Applied physics of compressible and incompressible fluids
T2  - Critical care nephrology / [Hrsg.:] Claudio Ronco and Rinaldo Bellomo
Y1  - 1998
SN  - 978-94-010-6306-7
SP  - 63
EP  - 84
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
T1  - Verbundforschungsprojekt Multimediale 3D-Visualisierung der Herzmuskelerregung
JF  - Intelligente, innovative Produktentwicklung  für  die  industrielle  Praxis. Stenzel, Horst [Hrsg.]
Y1  - 2001
N1  - Forschungsverbund Multimedia an Fachhochschulen in Nordrhein-Westfalen
SP  - 99
EP  - 112
PB  - Forschungverbund Multimedia an Fachhochschulen
CY  - Köln
ER  - 
TY  - JOUR
A1  - Warmer, Johannes
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
A1  - Kaul, Peter
T1  - Detection of triacetone triperoxide using temperature cycled metal-oxide semiconductor gas sensors
JF  - Physica status solidi (a)
Y1  - 2015
U6  - https://doi.org/10.1002/pssa.201431882
SN  - 1862-6319
VL  - 212
IS  - 6
SP  - 1289
EP  - 1298
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Warerkar, Shashikant
A1  - Schmitz, Stefan
A1  - Göttsche, Joachim
A1  - Hoffschmidt, Bernhard
A1  - Reißel, Martin
A1  - Tamme, Rainer
T1  - Air-Sand Heat Exchanger for High-Temperature Storage
JF  - Journal of Solar Energy Engineering. 133 (2011), H. 2
Y1  - 2011
SN  - 0199-6231
N1  - 7 pages
SP  - 021010
PB  - ASME
CY  - New York
ER  - 
TY  - JOUR
A1  - Wang, J.
A1  - Krause, R.
A1  - Block, K.
A1  - Musameh, M.
A1  - Mulchandani, A.
A1  - Schöning, Michael Josef
T1  - Flow injection amperometric detection of OP nerve agents based on organophosphorus-hydrolase biosensor detector
JF  - Biosensors & Bioelectronics. 18 (2003), H. 2-3
Y1  - 2003
SN  - 0956-5663
SP  - 255
EP  - 260
ER  - 
TY  - PAT
A1  - Wandrey, Christian
A1  - Biselli, Manfred
A1  - Schröder, Bernd
A1  - Schmoll, Hans-Joachim
T1  - Culturing cells on macroporous glass carriers coated with gelatin, extracellular matrix protein and stromal cells
Y1  - 1999
N1  - United States Patent 5,906,940 May 25, 1999
SP  - 1
EP  - 12
ER  - 
TY  - JOUR
A1  - Waldvogel, Janice
A1  - Ritzmann, Ramona
A1  - Freyler, Kathrin
A1  - Helm, Michael
A1  - Monti, Elena
A1  - Albracht, Kirsten
A1  - Stäudle, Benjamin
A1  - Gollhofer, Albert
A1  - Narici, Marco
T1  - The Anticipation of Gravity in Human Ballistic Movement
JF  - Frontiers in Physiology
N2  - Stretch-shortening type actions are characterized by lengthening of the pre-activated muscle-tendon unit (MTU) in the eccentric phase immediately followed by muscle shortening. Under 1 g, pre-activity before and muscle activity after ground contact, scale muscle stiffness, which is crucial for the recoil properties of the MTU in the subsequent push-off. This study aimed to examine the neuro-mechanical coupling of the stretch-shortening cycle in response to gravity levels ranging from 0.1 to 2 g. During parabolic flights, 17 subjects performed drop jumps while electromyography (EMG) of the lower limb muscles was combined with ultrasound images of the gastrocnemius medialis, 2D kinematics and kinetics to depict changes in energy management and performance. Neuro-mechanical coupling in 1 g was characterized by high magnitudes of pre-activity and eccentric muscle activity allowing an isometric muscle behavior during ground contact. EMG during pre-activity and the concentric phase systematically increased from 0.1 to 1 g. Below 1 g the EMG in the eccentric phase was diminished, leading to muscle lengthening and reduced MTU stretches. Kinetic energy at take-off and performance were decreased compared to 1 g. Above 1 g, reduced EMG in the eccentric phase was accompanied by large MTU and muscle stretch, increased joint flexion amplitudes, energy loss and reduced performance. The energy outcome function established by linear mixed model reveals that the central nervous system regulates the extensor muscles phase- and load-specifically. In conclusion, neuro-mechanical coupling appears to be optimized in 1 g. Below 1 g, the energy outcome is compromised by reduced muscle stiffness. Above 1 g, loading progressively induces muscle lengthening, thus facilitating energy dissipation.
Y1  - 2021
U6  - https://doi.org/10.3389/fphys.2021.614060
SN  - 1664-042X
PB  - Frontiers
CY  - Lausanne
ER  - 
TY  - JOUR
A1  - Waldvogel, Janice
A1  - Freyler, Kathrin
A1  - Helm, Michael
A1  - Monti, Elena
A1  - Stäudle, Benjamin
A1  - Gollhofer, Albert
A1  - Narici, Marco V.
A1  - Ritzmann, Ramona
A1  - Albracht, Kirsten
T1  - Changes in gravity affect neuromuscular control, biomechanics, and muscle-tendon mechanics in energy storage and dissipation tasks
JF  - Journal of Applied Physiology
N2  - This study evaluates neuromechanical control and muscle-tendon interaction during energy storage and dissipation tasks in hypergravity. During parabolic flights, while 17 subjects performed drop jumps (DJs) and drop landings (DLs), electromyography (EMG) of the lower limb muscles was combined with in vivo fascicle dynamics of the gastrocnemius medialis, two-dimensional (2D) kinematics, and kinetics to measure and analyze changes in energy management. Comparisons were made between movement modalities executed in hypergravity (1.8 G) and gravity on ground (1 G). In 1.8 G, ankle dorsiflexion, knee joint flexion, and vertical center of mass (COM) displacement are lower in DJs than in DLs; within each movement modality, joint flexion amplitudes and COM displacement demonstrate higher values in 1.8 G than in 1 G. Concomitantly, negative peak ankle joint power, vertical ground reaction forces, and leg stiffness are similar between both movement modalities (1.8 G). In DJs, EMG activity in 1.8 G is lower during the COM deceleration phase than in 1 G, thus impairing quasi-isometric fascicle behavior. In DLs, EMG activity before and during the COM deceleration phase is higher, and fascicles are stretched less in 1.8 G than in 1 G. Compared with the situation in 1 G, highly task-specific neuromuscular activity is diminished in 1.8 G, resulting in fascicle lengthening in both movement modalities. Specifically, in DJs, a high magnitude of neuromuscular activity is impaired, resulting in altered energy storage. In contrast, in DLs, linear stiffening of the system due to higher neuromuscular activity combined with lower fascicle stretch enhances the buffering function of the tendon, and thus the capacity to safely dissipate energy.
KW  - electromyography
KW  - locomotion
KW  - overload
KW  - stretch-shortening cycle
KW  - ultrasound
Y1  - 2023
U6  - https://doi.org/10.1152/japplphysiol.00279.2022
SN  - 1522-1601 (Onlineausgabe)
SN  - 8750-7587 (Druckausgabe)
VL  - 134
IS  - 1
SP  - 190
EP  - 202
PB  - American Physiological Society
CY  - Bethesda, Md.
ER  - 
TY  - CHAP
A1  - Wagner, Torsten
A1  - Yoshinobu, T.
A1  - Schöning, Michael Josef
T1  - Light-addressable potentiometric sensor as semiconductor-based sensor platform for (bio-) chemical sensing
T2  - Armenian Journal of Physics
Y1  - 2008
SN  - 1829-1171
SP  - 99
EP  - 103
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Yoshinobu, T.
A1  - Rao, C.
A1  - Otto, R.
A1  - Schöning, Michael Josef
T1  - „All-in-one“ solid-state device based on a lightaddressable potentiometric sensor platform
JF  - Transducers '05 : the 13th International Conference on Solid-State Sensors, Actuators and Microsystems ; Seoul, Korea, [June 5 - 9, 2005] ; digest of technical papers / sponsored by Korean Sensors Society. Technical co-sponsors: IEEE Electron Devices Society
Y1  - 2005
SN  - 0-7803-83995-6
N1  - International Conference on Solid State Sensors, Actuators and Microsystems ; (13, 2005, Seoul)
SP  - 1872
EP  - 1875
PB  - IEEE Operations Center
CY  - Piscataway, NJ
ER  - 
TY  - CHAP
A1  - Wagner, Torsten
A1  - Yoshinobu, T.
A1  - Otto, R.
A1  - Rao, C.
A1  - Molina, R.
A1  - Schöning, Michael Josef
T1  - Licht-adressierbare potentiometrische Sensorsysteme – Konzepte und Anwendungen
T2  - Sensoren und Mess-Systeme 2006 : Vorträge der 13. ITG/GMA-Fachtagung vom 13. bis 14.3.2006 in Freiburg/Breisgau
Y1  - 2006
SN  - 3-8007-2939-3
SP  - 165
EP  - 168
PB  - VDE Verl.
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Werner, Frederik
A1  - Miyamoto, Ko-Ichiro
A1  - Schöning, Michael Josef
A1  - Yoshinobu, Tatsuo
T1  - Development and characterisation of a compact light-addressable potentiometric sensor (LAPS) based on the digital light processing (DLP) technology for flexible chemical imaging
JF  - Sensors and Actuators B: Chemical
N2  - Chemical imaging systems allow the visualisation of the distribution of chemical species on the sensor surface. This work represents a new flexible approach to read out light-addressable potentiometric sensors (LAPS) with the help of a digital light processing (DLP) set-up. The DLP, known well for video projectors, consists of a mirror-array MEMS device, which allows fast and flexible generation of light patterns. With the help of these light patterns, the sensor surface of the LAPS device can be addressed. The DLP approach has several advantages compared to conventional LAPS set-ups, e.g., the spot size and the shape of the light pointer can be changed easily and no mechanical movement is necessary, which reduces the size of the set-up and increases the stability and speed of the measurement. In addition, the modulation frequency and intensity of the light beam are important parameters of the LAPS set-up. Within this work, the authors will discuss two different ways of light modulation by the DLP set-up, investigate the influence of different modulation frequencies and different light intensities as well as demonstrate the scanning capabilities of the new set-up by pH mapping on the sensor surface.
Y1  - 2012
U6  - https://doi.org/10.1016/j.snb.2010.12.003
SN  - 0925-4005
N1  - Part of special issue "Eurosensors XXIV, 2010"
VL  - 170
SP  - 34
EP  - 39
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Werner, Frederik
A1  - Miyamoto, Ko-Ichiro
A1  - Schöning, Michael Josef
A1  - Yoshinobu, Tatsuo
T1  - A high-density multi-point LAPS set-up using a VCSEL array and FPGA control
JF  - Sensors and Actuators B: Chemical. 154 (2011), H. 2
Y1  - 2011
SN  - 1873-3077
N1  - EUROSENSORS XXIII
SP  - 124
EP  - 128
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Werner, Frederik
A1  - Miyamoto, Ko-ichiro
A1  - Ackermann, Hans-Josef
A1  - Yoshinobu, Tatsuo
A1  - Schöning, Michael Josef
T1  - FPGA-based LAPS device for the flexible design of sensing sites on functional interfaces
JF  - Physica Status Solidi (A). 207 (2010), H. 4
Y1  - 2010
SN  - 1862-6300
N1  - Special Issue: Engineering of Functional Interfaces EnFI 2009
SP  - 844
EP  - 849
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Werner, Frederik
A1  - Miyamoto, K.
A1  - Schöning, Michael Josef
A1  - Yoshinobu, T.
T1  - A high-density multi-point LAPS set-up using a VCSEL array and FPGA control
JF  - Procedia Chemistry. 1 (2009), H. 1
Y1  - 2009
SN  - 1876-6196
N1  - Proceedings of the Eurosensors XXIII conference ; Eurosensors 23
SP  - 1483
EP  - 1486
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Vornholt, Wolfgang
A1  - Werner, Frederik
A1  - Yoshinobu, Tatsuo
A1  - Miyamoto, Ko-Ichiro
A1  - Keusgen, Michael
A1  - Schöning, Michael Josef
T1  - Light-addressable potentiometric sensor (LAPS) combined with magnetic beads for pharmaceutical screening
JF  - Physics in medicine
N2  - The light-addressable potentiometric sensor (LAPS) has the unique feature to address different regions of a sensor surface without the need of complex structures. Measurements at different locations on the sensor surface can be performed in a common analyte solution, which distinctly simplifies the fluidic set-up. However, the measurement in a single analyte chamber prevents the application of different drugs or different concentrations of a drug to each measurement spot at the same time as in the case of multi-reservoir-based set-ups. In this work, the authors designed a LAPS-based set-up for cell culture screening that utilises magnetic beads loaded with the endotoxin (lipopolysaccharides, LPS), to generate a spatially distributed gradient of analyte concentration. Different external magnetic fields can be adjusted to move the magnetic beads loaded with a specific drug within the measurement cell. By recording the metabolic activities of a cell layer cultured on top of the LAPS surface, this work shows the possibility to apply different concentrations of a sample along the LAPS measurement spots within a common analyte solution.
Y1  - 2016
U6  - https://doi.org/10.1016/j.phmed.2016.03.001
SN  - 2352-4510
VL  - 2016
IS  - 1
SP  - 2
EP  - 7
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Shigiahara, N.
A1  - Miyamoto, K.
A1  - Suzurikawa, J.
A1  - Finger, F.
A1  - Schöning, Michael Josef
A1  - Yoshinobu, T.
T1  - Light-addressable Potentiometric Sensors and Light–addressable Electrodes as a Combined Sensor-and-manipulator Microsystem with High Flexibility
JF  - Procedia Engineering
N2  - This work describes the novel combination of the light-addressable electrode (LAE) and the light-addressable potentiometric sensor (LAPS) into a microsystem set-up. Both the LAE as well as the LAPS shares the principle of addressing the active spot by means of a light beam. This enables both systems to manipulate resp. to detect an analyte with a high spatial resolution. Hence, combining both principles into a single set-up enables the active stimulation e.g., by means of electrolysis and a simultaneous observation e.g., the response of an entrapped biological cell by detection of extracellular pH changes. The work will describe the principles of both technologies and the necessary steps to integrate them into a single set-up. Furthermore, examples of application and operation of such systems will be presented.
Y1  - 2012
U6  - https://doi.org/10.1016/j.proeng.2012.09.290
SN  - 1877-7058
N1  - Part of special issue "26th European Conference on Solid-State Transducers, EUROSENSOR 2012"
IS  - 47
SP  - 890
EP  - 893
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Otto, R.
A1  - Yoshinobu, T.
T1  - A handheld 16 channel pen-type LAPS as a platform for (bio-)electrochemical sensing
JF  - Biomedizinische Technik. 49 (2004), H. 2
Y1  - 2004
SN  - 0932-4666
SP  - 996
EP  - 997
ER  - 
TY  - CHAP
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
T1  - Preface of the Special Issue of I3S 2005 in Jülich (Germany)
N2  - International Symposium on Sensor Science, I3S 2005 <3; 2005; Juelich, Germany> In: Sensors 2006, 6, 260-261 ISSN 1424-8220
KW  - Biosensor
KW  - I3S 2005
KW  - International Symposium on Sensor Science
Y1  - 2006
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-1365
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
T1  - Light-addressable potentiometric sensors (LAPS): recent trends and applications
JF  - Electrochemical sensor analysis / edited by S. Alegret ...
Y1  - 2007
SN  - 978-0-444-53053-0
N1  - Wilson & Wilson's comprehensive analytical chemistry ; 49
SP  - 87
EP  - 128
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Rao, C.
A1  - Otto, R.
A1  - Yoshinobu, T.
A1  - Kloock, Joachim P.
A1  - Schöning, Michael Josef
T1  - Chipkarten-basierter Multikanal lichtadressierbarer potentiometrischer Sensor für analytische Anwendungen in flüssigen Medien
JF  - Neue Herausforderungen und Anwendungen in der Sensortechnik : 7. Dresdner Sensor-Symposium ; 12. - 14. Dezember 2005, Dresden / [Forschungsgesellschaft für Messtechnik, Sensorik und Medizintechnik e.V.]. Gerald Gerlach ... (Hg.)
Y1  - 2005
SN  - 3-938863-29-3
N1  - Dresdner Beiträge zur Sensorik ; 24
SP  - 11
EP  - 14
PB  - TUDpress
CY  - Dresden
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Rao, C.
A1  - Kloock, Joachim P.
A1  - Yoshinobu, T.
A1  - Otto, R.
A1  - Keusgen, M.
A1  - Schöning, Michael Josef
T1  - “LAPS Card”—A novel chip card-based light-addressable potentiometric sensor (LAPS)
JF  - Sensors and Actuators B: Chemical. 118 (2006), H. 1-2
Y1  - 2006
SN  - 0925-4005
N1  - Eurosensors XIX - Eurosensors XIX - The 19th European Conference on Solid-State Transducers
SP  - 33
EP  - 40
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Molina, Roberto
A1  - Yoshinobu, Tatsuo
A1  - Kloock, Joachim P.
A1  - Biselli, Manfred
A1  - Canzoneri, Michele
A1  - Schnitzler, Thomas
A1  - Schöning, Michael Josef
T1  - Handheld multi-channel LAPS device as a transducer platform for possible biological and chemical multi-sensor applications
JF  - Electrochimica Acta. 53 (2007), H. 2
Y1  - 2007
SN  - 0013-4686
SP  - 305
EP  - 311
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Molina, R.
A1  - Biselli, Manfred
A1  - Canzoneri, Michele
A1  - Schnitzler, Thomas
A1  - Yoshinobu, Tatsuo
A1  - Schöning, Michael Josef
T1  - A light-addressable potentiometric sensor system for fast, simultaneous and spatial detection of the metabolic activity of biological cells
JF  - Transducers '07 Eurosensors XXI : digest of technical papers ; the14th International Conference on Solid-State Sensors, Actuators and Microsystems, June 10-14, 2007, Lyon, France / Gilles Delapierre (Ed.)
Y1  - 2007
SN  - 1-4244-0841-5
N1  - Eurosensors 21, 2007, Lyon ; International Conference on Solid-State Sensors, Actuators and Microsystems 14, 2007, Lyon
SP  - 1107
EP  - 1110
PB  - IEEE
CY  - Piscataway
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Miyamoto, Ko-ichiro
A1  - Shigihara, Noriko
A1  - Schöning, Michael Josef
A1  - Yoshinobu, Tatsuo
T1  - Microfluidic systems with free definable sensor spots by an integrated light-addressable potentiometric sensor
JF  - Procedia Engineering. 25 (2011)
Y1  - 2011
SN  - 1877-7058
N1  - EurosensorsXXV ; Proc. Eurosensors XXV, September 4-7, 2011, Athens, Greece
SP  - 791
EP  - 794
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Miyamoto, Ko-ichiro
A1  - Schöning, Michael Josef
A1  - Yoshinobu, Tatsuo
T1  - Novel combination of digital light processing (DLP) and light-addressable potentiometric sensors (LAPS) for flexible chemical imaging
JF  - Procedia Engineering. 5 (2010)
Y1  - 2010
SN  - 1877-7058
N1  - Eurosensor XXIV Conference
SP  - 520
EP  - 523
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Miyamoto, K.
A1  - Werner, Frederik
A1  - Schöning, Michael Josef
A1  - Yoshinobu, T.
T1  - Flexible electrochemical imaging with “zoom-in” functionality by using a new type of light-addressable potentiometric sensor
Y1  - 2011
N1  - 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference (TRANSDUCERS) , Date: 5-9 June 2011
SP  - 2133
EP  - 2135
PB  - IEEE
CY  - New York
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Miyamoto, K.
A1  - Werner, Frederik
A1  - Schöning, Michael Josef
A1  - Yoshinobu, T.
T1  - Utilising Digital Micro-Mirror Device (DMD) as Scanning Light Source for Light-Addressable Potentiometric Sensors (LAPS)
Y1  - 2011
U6  - https://doi.org/10.1166/sl.2011.1620
VL  - 9
IS  - 2
SP  - 812
EP  - 815
PB  - American Scientific Publishers
CY  - Stevenson Ranch, Calif.
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Maris, Rob J.
A1  - Ackermann, Hans-Josef
A1  - Otto, Ralph
A1  - Beging, Stefan
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Handheld measurement device for field-effect sensor structures: Practical evaluation and limitations
JF  - Sensors and Actuators B: Chemical  . 127 (2007), H. 1
Y1  - 2007
SN  - 0925-4005
SP  - 217
EP  - 223
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Kloock, Joachim P.
A1  - Schöning, Michael Josef
T1  - Determination of cadmium concentration and pH value in aqueous solutions by means of a handheld light-addressable potentiometric sensor (LAPS) device
JF  - Electrochemical sensor analysis / edited by S. Alegret ...
Y1  - 2007
SN  - 978-0-444-53133-9
N1  - Wilson & Wilson's comprehensive analytical chemistry ; 49
SP  - e35
EP  - e44
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Beging, Stefan
A1  - Rotter, L.
A1  - Poghossian, Arshak
A1  - Biselli, Manfred
A1  - Zang, Werner
A1  - Schöning, Michael Josef
T1  - Online-Messsysteme für die automatisierte Charakterisierung von feldeffektbasierten Biosensoren
JF  - 8. Dresdner Sensor-Symposium : Sensoren für Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme für die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung für die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.)
Y1  - 2007
SN  - 978-3-940046-45-1
N1  - Dresdner Sensor-Symposium <8, 2007, Dresden> ; Dresdner Beiträge zur Sensorik ; 29
SP  - 257
EP  - 260
PB  - TUDpress, Verl. der Wissenschaften
CY  - Dresden
ER  - 
TY  - CHAP
A1  - Wagner, Thorsten
A1  - Kohl, Claus-Dieter
A1  - Fröba, Michael
A1  - Tiemann, Michael
T1  - Gas sensing properties of ordered mesoporous SnO2
N2  - We report on the synthesis and CO gas-sensing properties of mesoporous tin(IV) oxides (SnO2). For the synthesis cetyltrimethylammonium bromide (CTABr) was used as a structure-directing agent; the resulting SnO2 powders were applied as films to commercially available sensor substrates by drop coating. Nitrogen physisorption shows specific surface areas up to 160 m2·g-1 and mean pore diameters of about 4 nm, as verified by TEM. The film conductance was measured in dependence on the CO concentration in humid synthetic air at a constant temperature of 300 °C. The sensors show a high sensitivity at low CO concentrations and turn out to be largely insensitive towards changes in the relative humidity. We compare the materials with commercially available SnO2-based sensors.
KW  - Biosensor
KW  - Tin oxide
KW  - sensing properties
KW  - CO
KW  - humidity
Y1  - 2006
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-1422
ER  - 
TY  - JOUR
A1  - Wagner, Patrick
A1  - Doll, Theodor
A1  - Schöning, Michael Josef
T1  - Engineering of functional interfaces / Patrick Wagner ; Theodor Doll ; Michael J. Schöning (eds.)
JF  - Physica status solidi (A) : Applications and materials science
Y1  - 2014
U6  - https://doi.org/10.1002/pssa.201470241
SN  - 1521-396X (E-Book); 1862-6319 (E-Book); 0031-8965 (Print); 1862-6300 (Print)
VL  - 211
IS  - 6
SP  - 1339
EP  - 1339
PB  - Wiley-VCH
CY  - Weinheim
ER  -