TY - JOUR A1 - Bohndick, Carla A1 - Bosse, Elke A1 - Jänsch, Vanessa K. A1 - Barnat, Miriam T1 - How different diversity factors affect the perception of first-year requirements in higher education JF - Frontline Learning Research N2 - In the light of growing university entry rates, higher education institutions not only serve larger numbers of students, but also seek to meet first-year students’ ever more diverse needs. Yet to inform universities how to support the transition to higher education, research only offers limited insights. Current studies tend to either focus on the individual factors that affect student success or they highlight students’ social background and their educational biography in order to examine the achievement of selected, non-traditional groups of students. Both lines of research appear to lack integration and often fail to take organisational diversity into account, such as different types of higher education institutions or degree programmes. For a more comprehensive understanding of student diversity, the present study includes individual, social and organisational factors. To gain insights into their role for the transition to higher education, we examine how the different factors affect the students’ perception of the formal and informal requirements of the first year as more or less difficult to cope with. As the perceived requirements result from both the characteristics of the students and the institutional context, they allow to investigate transition at the interface of the micro and the meso level of higher education. Latent profile analyses revealed that there are no profiles with complex patterns of perception of the first-year requirements, but the identified groups rather differ in the overall level of perceived challenges. Moreover, SEM indicates that the differences in the perception largely depend on the individual factors self-efficacy and volition. Y1 - 2021 U6 - https://doi.org/10.14786/flr.v9i2.667 SN - 2295-3159 VL - 9 IS - 2 SP - 78 EP - 95 PB - EARLI ER - TY - JOUR A1 - Bohn, Dieter A1 - Funke, Harald A1 - Sürken, Norbert A1 - Kreitmeier, F. T1 - Numerical and experimental investigations on endwall contouring in a four-stage turbine JF - ASME Turbo Expo Land Sea & Air 2001 : June 4 - 8, 2001, New Orleans, Louisiana / IGTI, International Gas Turbine Institute. American Society of Mechanical Engineers. International Gas Turbine Institute .. Y1 - 2001 SN - 0-7918-3528-6 N1 - ASME-Paper 2001-GT-0481 PB - ASME CY - New York, NY ER - TY - JOUR A1 - Bohn, Dieter A1 - Funke, Harald A1 - Heuer, Tom A1 - Bütikofer, J. T1 - Numerical and experimental investigations of the influence of different swirl-ratios on the temperature streak equalization in a 4-stage turbine JF - ASME Turbo Expo 2000 ; Munich, May 8-11 2000 Y1 - 2000 N1 - ASME-paper ; 2000-GT-250 CY - Munich ER - TY - JOUR A1 - Bohn, Dieter A1 - Funke, Harald T1 - Experimental investigations into the nonuniform flow in a 4-stage turbine with special focus on the flow equalization in the first turbine stage JF - ASME TURBO EXPO, Proceedings of the ASME Turbo Expo, 2003 Y1 - 2003 SN - 0-7918-3689-4 N1 - ASME TURBO EXPO 2003, Proceedings, Vol. 6: Turbomachinery, Pt. A, Atlanta, US, Jun 16-19, 2003 SP - 281 EP - 289 ER - TY - JOUR A1 - Bohn, D. A1 - Funke, Harald A1 - Gier, J. T1 - Numerical and Experimental Investigations on the Flow in a 4-Stage Turbine with Special Focus on the Development of a Radial Temperature Streak JF - ASME Turbo Expo 1999, Indianapolis, USA, 1999 Y1 - 1999 N1 - ASME-Paper 99-GT-027 ER - TY - JOUR A1 - Bohn, D. A1 - Funke, Harald A1 - Gier, J. T1 - Temperature jet development in a cross-over channel JF - Third European Conference on Turbomachinery - fluid dynamics and thermodynamics : : 2 - 5 March 1999, Royal National Hotel, London, UK / organized by the Energy Transfer and Thermofluid Mechanics Group of the Institution of Mechanical Engineers (IMechE); with support and sponsorship from European Commission / Vol. B. Y1 - 1999 N1 - C557/158/99 ; IMechE conference transactions 1999-1B SP - 671 EP - 680 PB - Professional Engineering Publ. CY - Bury St. Edmunds ER - TY - JOUR A1 - Bogoyavlenskiy, A. P. A1 - Digel, Ilya A1 - Berezin, V. E. T1 - Assessment of dot-blot ELISA sensitivity on membrane sorbent using various peroxidase substrates N2 - The sensitivity of the peroxidase reaction in dot-blot ELISA significantly depends on the substrate. The highest sensitivity is observed using benzidine and diamine- phenol combinations as the substrates due to the reaction of the coupled oxidation (NADI) KW - Enzyme-linked immunosorbent assay KW - Peroxidase KW - ELISA KW - phenols KW - naphtols KW - aromatic amines Y1 - 1997 ER - TY - JOUR A1 - Bogoyavlenskiy, A. P. A1 - Berezin, V. E. A1 - Ogneva, A. V. A1 - Tolmacheva, V. P. A1 - Digel, Ilya A1 - Khudyakova, S. S. T1 - Immunostimulating activity of a saponin-containing extract of Saponaria officinalis JF - Voprosy virusologii Y1 - 1999 SN - 0507-4088 VL - 44 IS - 5 SP - 229 EP - 232 ER - TY - JOUR A1 - Boettcher, Martin A1 - Haselhuhn, Angelika A1 - Jakse, Gerhard A1 - Brehmer, Bernhard A1 - Kirschner-Hermanns, Ruth T1 - Overactive bladder syndrome: an underestimated long-term problem after treatment of patients with localized prostate cancer? JF - BJU international N2 - In this study we observed courses of micturition symptoms and differentiated degrees of symptoms for each point in time while also considering the impact of bothersomeness. Our data show that not only significantly more patients who have undergone BT suffer from OAB than those who have undergone RP, but also that those affected show significantly higher values for severity of OAB symptoms throughout the whole observation period of 36 months. Our data analysis further shows that variability of OAB symptoms as well as fluctuation of severity of OAB symptoms vary to a significantly higher degree after BT than after RP. Looking only at mean figures at a given point in time clearly underestimates the underlying problem. This fact is not reflected in the literature. KW - quality of life KW - prostate cancer KW - prostatectomy KW - incontinence KW - brachytherapy Y1 - 2012 U6 - https://doi.org/10.1111/j.1464-410X.2011.10623.x SN - 1365-2176 (E-Journal); 1464-410X (E-Journal); 0007-1331 (Print); 1464-4096 (Print) VL - 109 IS - 12 SP - 1824 EP - 1830 PB - Wiley-Blackwell CY - Oxford ER - TY - JOUR A1 - Boecker, Henning A1 - Kuwert, Torsten A1 - Langen, Karl-J. A1 - Lange, Herwig W. A1 - Czech, Norbert A1 - Ziemons, Karl A1 - Herzog, Hans A1 - Shikare, Shekar A1 - Weindl, Anton A1 - Feinendegen, Ludwig E. T1 - SPECT with HMPAO compared to PET with FDG in Huntington disease JF - Journal of Computer Assisted Tomography Y1 - 1994 SN - 1532-3145 VL - 18 IS - 4 SP - 542 EP - 548 ER - TY - JOUR A1 - Bode, Jürgen A1 - Schlake, Thomas A1 - Iber, Michaela A1 - Schübeler, Dirk A1 - Seibler, Jost A1 - Snezhkov, Evgeney A1 - Nikolaev, Lev T1 - The transgeneticist's toolbox: novel methods for the targeted modification of eukaryotic genomes JF - Biological Chemistry Y1 - 2000 U6 - https://doi.org/10.1515/BC.2000.103 SN - 1431-6730 VL - 381 IS - 9-10 SP - 801 EP - 813 ER - TY - JOUR A1 - Bode, J. A1 - Bartsch, J. A1 - Boulikas, T. A1 - Iber, M. A1 - Mielke, C. A1 - Schübeler, D. A1 - Seibler, Jost A1 - Benham, C. T1 - Transcription-promoting genomic sites in mammalia: their elucidation and architectural principles JF - Gene therapy & molecular biology Y1 - 1998 SN - 1529-9120 VL - 1 IS - 1 SP - 1 EP - 29 ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Wilson, Thomas L. T1 - The quantum temperature of accelerating cosmological models of an entangled Universe JF - Advances in Space Research. 35 (2005), H. 1 Y1 - 2005 SN - 0273-1177 SP - 111 EP - 115 ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Wilson, Thomas L. T1 - The entangled Universe JF - Relativistic Astrophysics and Cosmology, Proceedings of the 13th Course of the International School of Cosmic Ray Astrophysics, held in Erice, Italy, 2-14 June 2002 / edited by Maurice M. Shapiro ... [et al.] Y1 - 2004 SN - 981-238-727-7 SP - 23 EP - 38 PB - World Scientific Publishing CY - New Jersey, NJ ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Wilson, Thomas L. T1 - Observational cosmology from the moon. Wilson, Thomas, L.; Blome, Hans-Joachim JF - Engineering, construction, and operations in space V : proceedings of the Fifth International Conference on Space '96, Albuquerque, New Mexico, June 1-6, 1996 / sponsored by Aerospace Division of the American Society of Civil Engineers ... [et al.]; edite Y1 - 1996 SN - 0-7844-0177-2 SP - 864 EP - 870 PB - The Society CY - New York ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Wilson, Thomas L. T1 - Nanotechnology and Orbital Debris JF - Engineering, construction, and operations in space V : proceedings of the Fifth International Conference on Space '96, Albuquerque, New Mexico, June 1-6, 1996 / sponsored by Aerospace Division of the American Society of Civil Engineers ... [et al.]; edite Y1 - 1996 SN - 0-7844-0177-2 SP - 328 EP - 333 PB - The Society CY - New York ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Wilson, Thomas L. T1 - Nonlocal Cosmology JF - Bulletin of the American Physical Society. 40 (1996) Y1 - 1996 SN - 0003-0503 SP - 2121 EP - 2121 ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Seboldt, Wolfgang A1 - Dachwald, Bernd A1 - Richter, Lutz T1 - Proposal for an integrated European Space Exploration Study JF - Space Debris and Space Traffic Management Symposium 2004 : proceedings of the International Academy of Astronautics Space Debris and Space Traffic Management Symposium, held in conjunction with the 55th International Astronautical Congress (IAC), October 4 - 8, 2004, Vancouver, British Columbia, Canada / ed. by Joerg Bendisch Y1 - 2004 SN - 0-87703-523-7 N1 - Proceedings IAC-2004-IAA, 3.6.1.06; Space Debris and Space Traffic Management Symposium <2004, Vancouver, British Columbia> ; International Academy of Astronautics PB - Univelt CY - San Diego, Calif. ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Priester, Wolfgang T1 - Vacuum energy in cosmic dynamics JF - Astrophysics and Space Science. 117 (1985), H. 2 Y1 - 1985 SN - 0004-640X SP - 327 EP - 335 ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Priester, Wolfgang T1 - Urknall und Evolution des Kosmos. I. Einstein-Friedmann-Kosmos und das Neutrino-Problem JF - Naturwissenschaften. 71 (1984), H. 9 Y1 - 1984 SN - 0028-1042 SP - 456 EP - 467 ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Priester, Wolfgang T1 - Urknall und Evolution des Kosmos. II. Inflationär modifizierter Urknall und Eschatologie des Kosmos JF - Naturwissenschaften. 71 (1984), H. 10 Y1 - 1984 SN - 0028-1042 SP - 515 EP - 527 ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Priester, Wolfgang T1 - The problem of the primeval explosion: 'Big bang' or 'big bounce'? I JF - Sterne und Weltraum. 26 (1987) Y1 - 1987 SN - 0039-1263 SP - 83 EP - 89 ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Priester, W. A1 - Hoell, J. T1 - New Ways in Cosmology: II. Alternative Models for the Very Early Universe JF - Currents in high energy astrophysics : proceedings of the NATO Advanced Study Institute and Ninth Course of the International School of Cosmic Ray Astrophysics on Currents in High Energy Astrophysics, Ettore Majorana Centre, Erice, Sicily, Italy, 7 - 18 M Y1 - 1995 SN - 0-7923-3354-3 SP - 301 EP - 312 PB - Kluwer CY - Dordrecht [u.a.] ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Priester, W. A1 - Hoell, J. T1 - New Ways in Cosmology: I. Friedmann-Lemaitre Model Derived From the Lyman Alpha Forest in Quasar Spectra JF - Currents in high energy astrophysics : proceedings of the NATO Advanced Study Institute and Ninth Course of the International School of Cosmic Ray Astrophysics on Currents in High Energy Astrophysics, Ettore Majorana Centre, Erice, Sicily, Italy, 7 - 18 M Y1 - 1995 SN - 0-7923-3354-3 SP - 291 EP - 300 PB - Kluwer CY - Dordrecht [u.a.] ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Priester, W. T1 - Big Bounce in the very early Universe JF - Astronomy and Astrophysics. 250 (1991), H. 1 Y1 - 1991 SN - 0004-6361 SP - 43 EP - 49 ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Priester, W. T1 - Zum Problem des Urknalls: "Big Bang" oder "Big Bounce"? Teil 2 JF - Sterne und Weltraum. 26 (1987), H. 3 Y1 - 1987 SN - 0039-1263 SP - 140 EP - 144 ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Priester, W. T1 - Zum Problem des Urknalls JF - Sterne und Weltraum. 26 (1987), H. 2 Y1 - 1987 SN - 0039-1263 SP - 83 EP - 89 ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Mashhoon, B. T1 - Quasi-normal oscillations of a Schwarzschild black hole JF - Physics Letters A. 100 (1984), H. 5 Y1 - 1984 SN - 0375-9601 SP - 231 EP - 234 ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Kundt, Wolfgang T1 - Leptonic jets from young stellar objects? JF - Astrophysics and Space Science. 148 (1988), H. 2 Y1 - 1988 SN - 0004-640X SP - 343 EP - 361 ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Kundt, W. T1 - Hypersonic Jets from Young Stars in Molecular Clouds JF - Circumstellar matter : proceedings of the 122nd symposium of the Internat. Astronom. Union held in Heidelberg, FRG, June 23 - 27, 1986 / ed. by I. Appenzeller ... Y1 - 1987 SN - 90-277-2511-X SP - 73 EP - 74 PB - Reidel CY - Dordrecht u.a. ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Kosbow, Michael T1 - Perturbation of a satellite orbit by gravitational waves JF - Jahrbuch 2004 der Deutschen Gesellschaft für Luft- und Raumfahrt - Lilienthal-Oberth e.V. (DGLR) Y1 - 2004 SN - 0070-4083 N1 - DGLR-2004-168 SP - 2083 EP - 2088 PB - DGLR CY - Bonn ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Kosbow, Michael T1 - The Pioneer Anomaly in the context of non-Newtonian Gravity JF - International Astronautical Congress : final papers : October 17-21, 2005, Fukuoka, Japan Y1 - 2005 N1 - Proceedings IAC-2005-C1.P.20 ;International Astronautical Congress ; (56, 2005, Fukuoka, Japan) SP - 20 EP - 20 PB - International Astronautical Federation CY - Paris ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Hoell, Josef A1 - Priester, Wolfgang T1 - Kosmologie JF - Sterne und Weltraum : [enthält 45 Tab.] / Hrsg.: Wilhelm Raith. Autoren: Hans Joachim Blome ... 2., stark erw. und aktualisierte Aufl. Y1 - 2002 SN - 3-11-016866-9 N1 - Lehrbuch der Experimentalphysik ; 8 SP - 439 EP - 582 PB - de Gruyter CY - Berlin [u.a.] ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Chu, Y. A1 - Hoell, J A1 - Priester, W. T1 - On the observational discrimination of Friedmann-Lemaître models JF - Large Scale Structures of the Universe: Proceedings of the 130th Symposium of the International Astronomical Union, dedicated to the memory of Marc A. Aaronson (1950-1987) held in Balatonfured, Hungary, June 15-20, 1987. Edited by Jean Audouze, Marie-Christine Pelletan and Sandor Szalay. Y1 - 1988 SN - 90-277-2742-2 N1 - International Astronomical Union. Symposium no. 130 SP - 517 PB - Kluwer Academic Publishers CY - Dordrecht ER - TY - JOUR A1 - Blome, Hans-Joachim A1 - Chicone, Carmen A1 - Hehl, Friedrich W. A1 - Mashhoon, Bahram T1 - Nonlocal modification of Newtonian gravity JF - Physical Review D Y1 - 2010 SN - 0556-2821 N1 - 11 pages VL - 81 IS - 6 SP - 065020 ER - TY - JOUR A1 - Blome, Hans-Joachim T1 - Exploration des Weltalls. Raumfahrt und der Weg des Menschen in den Kosmos JF - Telepolis special. Wie Forscher und Raumfahrer Aliens aufspüren wollen Y1 - 2004 PB - Heise Zeitschriften Verlag CY - Hannover ER - TY - JOUR A1 - Blome, Hans-Joachim T1 - Eine Reise an die Grenzen von Raum und Zeit. Wie die Raumfahrt unser Bild vom Kosmos erweitert. JF - DLR- Nachrichten. Mitteilungen des Deutschen Zentrums für Luft- und Raumfahrt. 90 (1998) Y1 - 1998 SN - 0937-0420 N1 - Sonderausgabe zum Tag der Raumfahrt 20.8.1998 SP - 20 EP - 29 ER - TY - JOUR A1 - Blome, Hans-Joachim T1 - Wie funktionieren die aktiven Kerne der Galaxien? JF - Naturwissenschaften. 76 (1989), H. 7 Y1 - 1989 SN - 0028-1042 SP - 310 EP - 317 ER - TY - JOUR A1 - Blome, Hans-Joachim T1 - Sternstunden der Astronomie Extraterrestrische Grundlagenforschung JF - Kultur und Technik. 23 (1999), H. 1 Y1 - 1999 SN - 0344-5690 SP - 18 EP - 27 ER - TY - JOUR A1 - Blome, Hans-Joachim T1 - Das Quantenvakuum und die kosmologische Konstante JF - Physikalische Blätter. 45 (1989) Y1 - 1989 SN - 0342-4472 SP - 51 EP - 56 ER - TY - JOUR A1 - Blome, Hans-Joachim T1 - The scale of the universe: a unit of length JF - Comments on astrophysics. 17 (1994) Y1 - 1994 SN - 0146-2970 SP - 327 EP - 335 ER - TY - JOUR A1 - Blome, Hans-Joachim T1 - Raumfahrt - zwischen Himmel und Erde JF - Technologien für das 21. Jahrhundert / [red. Leitung: Birgit Strackenbrock ...] Y1 - 2000 SN - 376537945X N1 - Buchbeitrag SP - 572 EP - 679 PB - Brockhaus CY - Leipzig [u.a.] ER - TY - JOUR A1 - Blome, Hans-Joachim T1 - Kosmologie: Geschichte des Kosmos und Extrapolationen in die Zukunft JF - Der Mensch im Kosmos. 3. ; Berichtsband eines Workshops vom 19. bis 21. April 2001, Kurverwaltung, Medienzentrum Bad Oeynhausen : Der Mensch im Kosmos / Peter R. Sahm ; Gerhard P. J. Thiele (Hrsg.) Y1 - 2002 SN - 3-8265-9737-0 PB - Shaker CY - Aachen ER - TY - JOUR A1 - Blome, Hans-Joachim T1 - Die Entstehung des Kosmos - Vom Anfang der Welt bis zum komplexen Universum JF - Homo spaciens - der Mensch im Kosmos : ein interdisziplinärer Ausblick auf Ursprung und Zukunft des Menschen im All ; Berichtsband der Tagung "Mensch im Kosmos IV" vom 14. - 16.10.2004 auf Schloß Theuern/Oberpfalz / P. R. Sahm, ... Hans-Joachim Blome(Hrsg.) Y1 - 2005 SN - 3-9807330-8-4 N1 - Tagung Mensch im Kosmos (4, 2004, Theuern, Kümmersbruck) PB - Discorsi CY - Hamburg ER - TY - JOUR A1 - Blome, Hans-Joachim T1 - Raumfahrt und Exploration des Kosmos JF - Mensch, Leben, Schwerkraft, Kosmos : Perspektiven biowissenschaftlicher Weltraumforschung in Deutschland ; Berichtsband einer Klausurtagung vom 20. - 22.10.2000 in Stuttgart-Hohenheim/Birkach / Hinrich Rahmann ... (Hrsg.). [Ausgerichtet von der Deutschen Gesellschaft für Luft- und Raumfahrt medizin] Y1 - 2001 SN - 3-935380-03-8 SP - 80 EP - 105 PB - Heimbach CY - Stuttgart ER - TY - JOUR A1 - Blome, Hans-Joachim T1 - Aspekte der modernen Kosmologie JF - Mensch, Leben, Schwerkraft, Kosmos : Perspektiven biowissenschaftlicher Weltraumforschung in Deutschland ; Berichtsband einer Klausurtagung vom 20. - 22.10.2000 in Stuttgart-Hohenheim/Birkach / Hinrich Rahmann ... (Hrsg.). [Ausgerichtet von der Deutschen Gesellschaft für Luft- und Raumfahrt medizin] Y1 - 2001 SN - 3-935380-03-8 SP - 50 EP - 79 PB - Heimbach CY - Stuttgart ER - TY - JOUR A1 - Block, Simon A1 - Viebahn, Peter A1 - Jungbluth, Christian T1 - Analysing direct air capture for enabling negative emissions in Germany: an assessment of the resource requirements and costs of a potential rollout in 2045 JF - Frontiers in Climate N2 - Direct air capture (DAC) combined with subsequent storage (DACCS) is discussed as one promising carbon dioxide removal option. The aim of this paper is to analyse and comparatively classify the resource consumption (land use, renewable energy and water) and costs of possible DAC implementation pathways for Germany. The paths are based on a selected, existing climate neutrality scenario that requires the removal of 20 Mt of carbon dioxide (CO2) per year by DACCS from 2045. The analysis focuses on the so-called “low-temperature” DAC process, which might be more advantageous for Germany than the “high-temperature” one. In four case studies, we examine potential sites in northern, central and southern Germany, thereby using the most suitable renewable energies for electricity and heat generation. We show that the deployment of DAC results in large-scale land use and high energy needs. The land use in the range of 167–353 km2 results mainly from the area required for renewable energy generation. The total electrical energy demand of 14.4 TWh per year, of which 46% is needed to operate heat pumps to supply the heat demand of the DAC process, corresponds to around 1.4% of Germany's envisaged electricity demand in 2045. 20 Mt of water are provided yearly, corresponding to 40% of the city of Cologne‘s water demand (1.1 million inhabitants). The capture of CO2 (DAC) incurs levelised costs of 125–138 EUR per tonne of CO2, whereby the provision of the required energy via photovoltaics in southern Germany represents the lowest value of the four case studies. This does not include the costs associated with balancing its volatility. Taking into account transporting the CO2 via pipeline to the port of Wilhelmshaven, followed by transporting and sequestering the CO2 in geological storage sites in the Norwegian North Sea (DACCS), the levelised costs increase to 161–176 EUR/tCO2. Due to the longer transport distances from southern and central Germany, a northern German site using wind turbines would be the most favourable. KW - rollout KW - economics KW - Germany KW - negative emissions KW - carbon dioxide removal KW - climate neutrality KW - DAC KW - direct air capture Y1 - 2024 U6 - https://doi.org/10.3389/fclim.2024.1353939 SN - 2624-9553 VL - 6 PB - Frontiers CY - Lausanne ER - TY - JOUR A1 - Block, Franziska A1 - May, Alexander A1 - Wetzel, Katharina A1 - Adels, Klaudia A1 - Elbers, Gereon A1 - Schulze, Margit A1 - Monakhova, Yulia T1 - What is the best spectroscopic method for simultaneous analysis of organic acids and (poly)saccharides in biological matrices: Example of Aloe vera extracts? JF - Talanta Open N2 - Several species of (poly)saccharides and organic acids can be found often simultaneously in various biological matrices, e.g., fruits, plant materials, and biological fluids. The analysis of such matrices sometimes represents a challenging task. Using Aloe vera (A. vera) plant materials as an example, the performance of several spectro-scopic methods (80 MHz benchtop NMR, NIR, ATR-FTIR and UV–vis) for the simultaneous analysis of quality parameters of this plant material was compared. The determined parameters include (poly)saccharides such as aloverose, fructose and glucose as well as organic acids (malic, lactic, citric, isocitric, acetic, fumaric, benzoic and sorbic acids). 500 MHz NMR and high-performance liquid chromatography (HPLC) were used as the reference methods. UV–vis data can be used only for identification of added preservatives (benzoic and sorbic acids) and drying agent (maltodextrin) and semiquantitative analysis of malic acid. NIR and MIR spectroscopies combined with multivariate regression can deliver more informative overview of A. vera extracts being able to additionally quantify glucose, aloverose, citric, isocitric, malic, lactic acids and fructose. Low-field NMR measurements can be used for the quantification of aloverose, glucose, malic, lactic, acetic, and benzoic acids. The benchtop NMR method was successfully validated in terms of robustness, stability, precision, reproducibility and limit of detection (LOD) and quantification (LOQ), respectively. All spectroscopic techniques are useful for the screening of (poly)saccharides and organic acids in plant extracts and should be applied according to its availability as well as information and confidence required for the specific analytical goal. Benchtop NMR spectroscopy seems to be the most feasible solution for quality control of A. vera products. KW - Spectroscopy KW - (Poly)saccharides KW - Organic acids KW - Aloe vera KW - qNMR Y1 - 2023 U6 - https://doi.org/10.1016/j.talo.2023.100220 SN - 2666-8319 VL - 7 IS - Art. No. 100220 SP - 1 EP - 9 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Bleilevens, Christian A1 - Hill, Aileen A1 - Grzanna, Tim A1 - Fechter, Tamara A1 - Bohnen, Melanie A1 - Weber, Hans-Joachim A1 - Beckers, Christian A1 - Borosch, Sebastian A1 - Zayat, Rashad A1 - Benstoem, Carin A1 - Rossaint, Rolf A1 - Goetzenich, Andreas T1 - In vitro head-to-head comparison of anticoagulation properties of two heparin brands in a human blood miniature mock loop JF - Interactive cardiovascular and thoracic surgery Y1 - 2019 U6 - https://doi.org/10.1093/icvts/ivy206 SN - 1569-9285 VL - 28 IS - 1 SP - 120 EP - 127 ER - TY - JOUR A1 - Blecken, Udo A1 - Holthaus-Sellheier, Ursula T1 - Quantitative Prognoseverfahren für den Büroimmobilienmarkt, Tl.1 JF - GuG : Grundstücksmarkt und Grundstückswert Y1 - 2011 SN - 0938-0175 VL - 21 IS - 1 SP - 30 EP - 39 PB - Werner CY - Köln ER -