TY - JOUR A1 - Schöning, Michael Josef A1 - Kloock, Joachim P. A1 - Knobbe, D.-T. A1 - Räde, J. A1 - Keusgen, M. T1 - Silicon field-effect biosensor for cyanide detection JF - Technical digest of the 10th International Meeting on Chemical Sensors, July 11 - 14, 2004, Tsukuba, Japan / Japan Association of Chemical Sensors Y1 - 2004 N1 - Chemical sensors ; 20.2004 Suppl. B. IMCS ; (10, 2004, Tsukuba) ; International Meeting on Chemical Sensors ; (10 : ; 2004.07.11-14 : ; Tsukuba) SP - 98 EP - 99 PB - Japan Association of Chemical Sensors CY - Fukuoka ER - TY - JOUR A1 - Schöning, Michael Josef T1 - Silicon recognizes biochemical parameters: Microchips for analytical sensor applications JF - American Laboratory. 32 (2000), H. 16 Y1 - 2000 SN - 0044-7749 SP - 24 EP - 31 ER - TY - JOUR A1 - Schöning, Michael Josef T1 - Silicon-based biochemical sensors JF - CNI - The Center of Nanoelectronic Systems for Information Technology Y1 - 2003 SP - 165 EP - 170 PB - Foschungszentrum Jülich ER - TY - CHAP A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - Silicon-based chemical and biological field-effect sensors T2 - Encyclopedia of Sensors. Vol. 9 S - Sk Y1 - 2006 SN - 1-58883-065-9 SP - 463 EP - 534 PB - ASP, American Scientific Publ. CY - Stevenson Ranch, Calif. ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Poghossian, Arshak T1 - Silicon-based field-effect devices for (bio-)chemical sensing JF - International Conference on Advanced Semiconductor Devices and Microsystems, 2008. ASDAM 2008 Y1 - 2008 SN - 978-1-4244-2325-5 SP - 31 EP - 38 CY - Smolenice, Slovakia ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Poghossian, Arshak T1 - Silicon-based field-effect devices with nanostructured surfaces for bio-/chemical sensing JF - Semiconductor micro- and nanoelectronics : Proceedings of the Seventh International Conference , Tsakhcadzor, Armenia July 3-5 2009 Y1 - 2009 SP - 51 EP - 53 ER - TY - JOUR A1 - Schöning, Michael Josef T1 - Silicon-based field-effect structures – From dielectrics to bioelectronics JF - Dielectrics in emerging technologies : proceedings of the international symposium ; [papers presented at the First International Symposium on Science and Technology of Dielectrics in Emerging Fields held from 27th April to 2nd May 2003 in Paris, France] / sponsoring divisions: Dielectric Science and Technology, Electronics. Ed.: D. Misra. Y1 - 2003 SN - 1-56677-346-6 N1 - International Symposium on Science and Technology of Dielectrics in Emerging Fields ; (1, 2003, Paris) SP - 31 EP - 37 PB - Electrochemical Society CY - Pennington, NJ ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Wagner, Torsten A1 - Schöning, Michael Josef A1 - Pieper, Martin T1 - Simulating the electromagnetic‐thermal treatment of thin aluminium layers for adhesion improvement JF - Physica status solidi (a) N2 - A composite layer material used in packaging industry is made from joining layers of different materials using an adhesive. An important processing step in the production of aluminium-containing composites is the surface treatment and consequent coating of adhesive material on the aluminium surface. To increase adhesion strength between aluminium layer and the adhesive material, the foil is heat treated. For efficient heating, induction heating was considered as state-of-the-art treatment process. Due to the complexity of the heating process and the unpredictable nature of the heating source, the control of the process is not yet optimised. In this work, a finite element analysis of the process was established and various process parameters were studied. The process was simplified and modelled in 3D. The numerical model contains an air domain, an aluminium layer and a copper coil fitted with a magnetic field concentrating material. The effect of changing the speed of the aluminium foil (or rolling speed) was studied with the change of the coil current. Statistical analysis was used for generating a general control equation of coil current with changing rolling speed. Y1 - 2015 U6 - http://dx.doi.org/10.1002/pssa.201431893 SN - 1862-6319 VL - Vol. 212 IS - 6 SP - 1234 EP - 1241 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Turek, Monik A1 - Heiden, Wolfgang A1 - Guo, Sharon A1 - Riesen, Alfred A1 - Schubert, Jürgen A1 - Zander, Willi A1 - Krüger, Peter A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Simultaneous detection of cyanide and heavy metals for environmental analysis by means of µISEs JF - Physica Status Solidi (A). 207 (2010), H. 4 Y1 - 2010 SN - 1862-6300 N1 - Special Issue: Engineering of Functional Interfaces EnFI 2009 SP - 817 EP - 823 ER - TY - JOUR A1 - Furuichi, K. A1 - Yoshinobu, T. A1 - Ermelenko, T. A1 - Mourzina, Y. A1 - Iwasaki, H. A1 - Schöning, Michael Josef T1 - Simultaneous visualization of multiple ions by the chemical imaging sensor JF - Proceedings of the 5th East Asian Conference on Chemical Sensors; the 33rd Chemical Sensor Symposium : December 4 - 7, 2001, Huis Ten Bosch, Sasebo-shi, Nagasaki, Japan / Japan Association of Chemical Sensors; the Electrochemical Society of Japan Y1 - 2001 N1 - Chemical sensors; 17.2001 Suppl. B; East Asian Conference on Chemical Sensors ; (5, 2001; Nagasaki) SP - 399 EP - 401 PB - Japan Association of Chemical Sensors CY - Kasuga, Fukuoka-ken ER - TY - JOUR A1 - Rachinger, Michael A1 - Bauch, Melanie A1 - Strittmatter, Axel A1 - Bongaerts, Johannes A1 - Evers, Stefan A1 - Maurer, Karl-Heinz A1 - Daniel, Rolf A1 - Liebl, Wolfgang A1 - Liesegang, Heiko A1 - Ehrenreich, Armin T1 - Size unlimited markerless deletions by a transconjugative plasmid-system in Bacillus licheniformis JF - Journal of biotechnology Y1 - 2013 SN - 1873-4863 (E-Journal); 0168-1656 (Print) VL - Vol. 164 IS - Iss. 4 SP - 365 EP - 369 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Vlasov, Y. G. A1 - Mourzina, Y. G. A1 - Legin, A. V. A1 - Ermelenko, Y. E. A1 - Schubert, J. A1 - Schöning, Michael Josef A1 - Lüth, H. T1 - Solid-state thin film sensors based on chalcogenide materials prepared by planar technology and pulsed laser deposition JF - Russian Journal of Applied Chemistry. 75 (2002), H. 3 Y1 - 2002 SN - 1070-4272 SP - 351 EP - 356 ER - TY - GEN A1 - Abdelghani, Adnane A1 - Menaa, Bouzid A1 - Obare, Sherine O. A1 - Schöning, Michael Josef T1 - Special issue on nanoscale science and technology / guest eds.: Adnane Abdelghani, Bouzid Menaa, Sherine O. Obare, Michael J. Schöning T2 - International journal of nanotechnology Y1 - 2013 SN - 1741-8151 (E-Journal), 1475-7435 (Print) VL - Vol. 10 IS - No. 5-7 SP - 373 EP - 619 ER - TY - JOUR A1 - Vitusevich, S. A. A1 - Förster, Arnold A1 - Reetz, W. A1 - Lüth, H. A1 - Belyaev, A. E. A1 - Danylyuk, S. V. T1 - Spectral Responsivity of single-quantum-well photodetectors JF - Applied Physics Letters. 77 (2000), H. 1 Y1 - 2000 SN - 1077-3118 SP - 16 EP - 18 ER - TY - JOUR A1 - Oberländer, Jan A1 - Mayer, Marlena A1 - Greeff, Anton A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Spore-based biosensor to monitor the microbicidal efficacy of gaseous hydrogen peroxide sterilization processes JF - Biosensors and Bioelectronics N2 - In this work, a spore-based biosensor is evaluated to monitor the microbicidal efficacy of sterilization processes applying gaseous hydrogen peroxide (H2O2). The sensor is based on interdigitated electrode structures (IDEs) that have been fabricated by means of thin-film technologies. Impedimetric measurements are applied to study the effect of sterilization process on spores of Bacillus atrophaeus. This resilient microorganism is commonly used in industry to proof the sterilization efficiency. The sensor measurements are accompanied by conventional microbiological challenge tests, as well as morphological characterizations with scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The sensor measurements are correlated with the microbiological test routines. In both methods, namely the sensor-based and microbiological one, a tailing effect has been observed. The results are evaluated and discussed in a three-dimensional calibration plot demonstrating the sensor's suitability to enable a rapid process decision in terms of a successfully performed sterilization. Y1 - 2018 U6 - http://dx.doi.org/10.1016/j.bios.2017.12.045 SN - 0956-5663 VL - 104 SP - 87 EP - 94 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Keusgen, M. A1 - Schöning, Michael Josef T1 - Strategies for biosensoric detection of potential drugs in nature JF - Biomedizinische Technik. 49 (2004), H. 2 Y1 - 2004 SN - 0932-4666 SP - 1004 EP - 1005 ER - TY - JOUR A1 - Oberländer, Jan A1 - Kirchner, Patrick A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Strategies in developing thin-film sensors for monitoring aseptic food processes : Theoretical considerations and investigations of passivation materials JF - Electrochimica Acta N2 - The sterilization of packages in aseptic food processes is highly significant to maintain a consumer-safe product with extended shelf-life. Today, the sterilization of food packages is predominantly accomplished by gaseous hydrogen peroxide (H2O2) in combination with heat. In order to monitor this sterilization process, calorimetric gas sensors as differential set-up of two platinum temperature sensors representing a catalytically active (additionally deposition of MnO2) and a passive segment have been recently developed. The temperature rise of the exothermic decomposition serves as an indicator of the present H2O2 concentration. In the present work, a theoretical approach considering the sensor’s thermochemistry and physical transport phenomena was formulated to evaluate the temperature rise based on the energy content of gaseous H2O2. In a further part of this work, three polymers have been analyzed with respect to their application as passivation materials. The examined polymers are photoresist SU-8, perfluoroalkoxy (PFA) and fluorinated ethylene propylene (FEP). Thermal analyses by means of differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) have been conducted to determine the operation limits of the polymers. The overall chemical resistance and stability of the polymers against the harsh environmental conditions during the sterilization process have been examined by attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR). Y1 - 2015 U6 - http://dx.doi.org/10.1016/j.electacta.2015.06.126 SN - 0013-4686 VL - 183 SP - 130 EP - 136 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Simonis, A. A1 - Lüth, H. A1 - Wang, J. A1 - Schöning, Michael Josef T1 - Strategies of miniaturised reference electrodes integrated in a silicon-based „one chip“ pH sensor JF - Sensors. 3 (2003), H. 9 Y1 - 2003 SN - 1424-8220 SP - 330 EP - 339 ER - TY - JOUR A1 - Schroeter, Rebecca A1 - Hoffmann, Tamara A1 - Voigt, Birgit A1 - Meyer, Hanna A1 - Bleisteiner, Monika A1 - Muntel, Jan A1 - Jürgen, Britta A1 - Albrecht, Dirk A1 - Becher, Dörte A1 - Lalk, Michael A1 - Evers, Stefan A1 - Bongaerts, Johannes A1 - Maurer, Karl-Heinz A1 - Putzer, Harald A1 - Hecker, Michael A1 - Schweder, Thomas A1 - Bremer, Erhard T1 - Stress responses of the industrial workhorse Bacillus licheniformis to osmotic challenges JF - PLoS ONE N2 - The Gram-positive endospore-forming bacterium Bacillus licheniformis can be found widely in nature and it is exploited in industrial processes for the manufacturing of antibiotics, specialty chemicals, and enzymes. Both in its varied natural habitats and in industrial settings, B. licheniformis cells will be exposed to increases in the external osmolarity, conditions that trigger water efflux, impair turgor, cause the cessation of growth, and negatively affect the productivity of cell factories in biotechnological processes. We have taken here both systems-wide and targeted physiological approaches to unravel the core of the osmostress responses of B. licheniformis. Cells were suddenly subjected to an osmotic upshift of considerable magnitude (with 1 M NaCl), and their transcriptional profile was then recorded in a time-resolved fashion on a genome-wide scale. A bioinformatics cluster analysis was used to group the osmotically up-regulated genes into categories that are functionally associated with the synthesis and import of osmostress-relieving compounds (compatible solutes), the SigB-controlled general stress response, and genes whose functional annotation suggests that salt stress triggers secondary oxidative stress responses in B. licheniformis. The data set focusing on the transcriptional profile of B. licheniformis was enriched by proteomics aimed at identifying those proteins that were accumulated by the cells through increased biosynthesis in response to osmotic stress. Furthermore, these global approaches were augmented by a set of experiments that addressed the synthesis of the compatible solutes proline and glycine betaine and assessed the growth-enhancing effects of various osmoprotectants. Combined, our data provide a blueprint of the cellular adjustment processes of B. licheniformis to both sudden and sustained osmotic stress. Y1 - 2014 U6 - http://dx.doi.org/10.1371/journal.pone.0080956 SN - 1932-6203 VL - 8 IS - 11 PB - PLOS CY - San Francisco ER - TY - JOUR A1 - Rosenauer, A. A1 - Oberst, W. A1 - Litvinov, D. A1 - Gerthsen, D. A1 - Förster, Arnold A1 - Schmidt, R. T1 - Structural and Chemical Investigation of In-0.6Ga0.4As Stranski-Krastanow Layers Burried in GaAs by Transmission Electron Microscopy JF - Physical Review B. 61 (2000), H. 12 Y1 - 2000 SN - 1095-3795 SP - 8276 EP - 8288 ER - TY - JOUR A1 - Srnanek, R. A1 - Geurts, J. A1 - Lentze, M. A1 - Irmer, G. A1 - Donoval, D. A1 - Brdecka, P. A1 - Kordos, P. A1 - Förster, Arnold A1 - Sciana, B. A1 - Radziewicz, D. A1 - Tlaczala, M. T1 - Study of d-doped GaAs layers by micro-Raman spectroscopy on bevelled samples JF - Applied surface science . 230 (2004), H. 1 -4 Y1 - 2004 SN - 0169-4332 N1 - ISSN der E-Ausg.: 0169-4332 SP - 379 EP - 385 ER - TY - JOUR A1 - Oberländer, Jan A1 - Jildeh, Zaid B. A1 - Kirchner, Patrick A1 - Wendeler, Luisa A1 - Bromm, Alexander A1 - Iken, Heiko A1 - Wagner, Patrick A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Study of Interdigitated Electrode Arrays Using Experiments and Finite Element Models for the Evaluation of Sterilization Processes JF - Sensors N2 - In this work, a sensor to evaluate sterilization processes with hydrogen peroxide vapor has been characterized. Experimental, analytical and numerical methods were applied to evaluate and study the sensor behavior. The sensor set-up is based on planar interdigitated electrodes. The interdigitated electrode structure consists of 614 electrode fingers spanning over a total sensing area of 20 mm2. Sensor measurements were conducted with and without microbiological spores as well as after an industrial sterilization protocol. The measurements were verified using an analytical expression based on a first-order elliptical integral. A model based on the finite element method with periodic boundary conditions in two dimensions was developed and utilized to validate the experimental findings. Y1 - 2015 U6 - http://dx.doi.org/10.3390/s151026115 SN - 1424-8220 N1 - This article belongs to the Special Issue "Gas Sensors—Designs and Applications" VL - 15 IS - 10 SP - 26115 EP - 26127 PB - MDPI CY - Basel ER - TY - CHAP A1 - Welden, Melanie A1 - Severins, Robin A1 - Poghossian, Arshak A1 - Wege, Christina A1 - Siegert, Petra A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Studying the immobilization of acetoin reductase with Tobacco mosaic virus particles on capacitive field-effect sensors T2 - 2022 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN) N2 - A capacitive electrolyte-insulator-semiconductor (EISCAP) biosensor modified with Tobacco mosaic virus (TMV) particles for the detection of acetoin is presented. The enzyme acetoin reductase (AR) was immobilized on the surface of the EISCAP using TMV particles as nanoscaffolds. The study focused on the optimization of the TMV-assisted AR immobilization on the Ta 2 O 5 -gate EISCAP surface. The TMV-assisted acetoin EISCAPs were electrochemically characterized by means of leakage-current, capacitance-voltage, and constant-capacitance measurements. The TMV-modified transducer surface was studied via scanning electron microscopy. KW - Tobacco mosaic virus KW - acetoin KW - capacitive field-effect biosensor KW - enzyme immobilization Y1 - 2022 SN - 978-1-6654-5860-3 (Online) SN - 978-1-6654-5861-0 (Print) U6 - http://dx.doi.org/10.1109/ISOEN54820.2022.9789657 N1 - IEEE International Symposium on Olfaction and Electronic Nose (ISOEN), 29 May 2022 - 01 June 2022, Aveiro, Portugal. PB - IEEE ER - TY - JOUR A1 - Beging, Stefan A1 - Leinhos, Marcel A1 - Jablonski, Melanie A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - Studying the spatially resolved immobilisation of enzymes on a capacitive field-effect structure by means of nano-spotting JF - Physica status solidi (a) Y1 - 2015 U6 - http://dx.doi.org/10.1002/pssa.201431891 SN - 1862-6319 VL - 212 IS - 6 SP - 1353 EP - 1358 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Arreola, Julio A1 - Oberländer, Jan A1 - Mätzkow, M. A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Surface functionalization for spore-based biosensors with organosilanes JF - Electrochimica Acta N2 - In the present work, surface functionalization of different sensor materials was studied. Organosilanes are well known to serve as coupling agent for biomolecules or cells on inorganic materials. 3-aminopropyltriethoxysilane (APTES) was used to attach microbiological spores time to an interdigitated sensor surface. The functionality and physical properties of APTES were studied on isolated sensor materials, namely silicon dioxide (SiO2) and platinum (Pt) as well as the combined material on sensor level. A predominant immobilization of spores could be demonstrated on SiO2 surfaces. Additionally, the impedance signal of APTES-functionalized biosensor chips has been investigated. Y1 - 2017 U6 - http://dx.doi.org/10.1016/j.electacta.2017.04.157 SN - 0013-4686 VL - 241 SP - 237 EP - 243 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Bronder, Thomas A1 - Poghossian, Arshak A1 - Jessing, Max P. A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Surface regeneration and reusability of label-free DNA biosensors based on weak polyelectrolyte-modified capacitive field-effect structures JF - Biosensors and Bioelectronics Y1 - 2019 U6 - http://dx.doi.org/10.1016/j.bios.2018.11.019 SN - 0956-5663 VL - 126 SP - 510 EP - 517 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Immel, Timo A1 - Grützke, Martin A1 - Späte, Anne-Katrin A1 - Groth, Ulrich A1 - Öhlschläger, Peter A1 - Huhn, Thomas T1 - Synthesis and X-ray structure analysis of a heptacoordinate titanium(IV)-bis-chelate with enhanced in vivo antitumor efficacy JF - Chemical Communications N2 - Chelate stabilization of a titanium(IV)–salan alkoxide by ligand exchange with 2,6-pyridinedicarboxylic acid (dipic) resulted in heptacoordinate complex 3 which is not redox-active, stable on silica gel and has increased aqueous stability. 3 is highly toxic in HeLa S3 and Hep G2 and has enhanced antitumor efficacy in a mouse cervical-cancer model. Y1 - 2012 U6 - http://dx.doi.org/10.1039/C2CC31624B SN - 1364-548X VL - 48 IS - 46 SP - 5790 EP - 5792 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Muschallik, Lukas A1 - Molinnus, Denise A1 - Jablonski, Melanie A1 - Kipp, Carina Ronja A1 - Bongaerts, Johannes A1 - Pohl, Martina A1 - Wagner, Torsten A1 - Schöning, Michael Josef A1 - Selmer, Thorsten A1 - Siegert, Petra T1 - Synthesis of α-hydroxy ketones and vicinal (R, R)-diols by Bacillus clausii DSM 8716ᵀ butanediol dehydrogenase JF - RSC Advances N2 - α-hydroxy ketones (HK) and 1,2-diols are important building blocks for fine chemical synthesis. Here, we describe the R-selective 2,3-butanediol dehydrogenase from B. clausii DSM 8716ᵀ (BcBDH) that belongs to the metal-dependent medium chain dehydrogenases/reductases family (MDR) and catalyzes the selective asymmetric reduction of prochiral 1,2-diketones to the corresponding HK and, in some cases, the reduction of the same to the corresponding 1,2-diols. Aliphatic diketones, like 2,3-pentanedione, 2,3-hexanedione, 5-methyl-2,3-hexanedione, 3,4-hexanedione and 2,3-heptanedione are well transformed. In addition, surprisingly alkyl phenyl dicarbonyls, like 2-hydroxy-1-phenylpropan-1-one and phenylglyoxal are accepted, whereas their derivatives with two phenyl groups are not substrates. Supplementation of Mn²⁺ (1 mM) increases BcBDH's activity in biotransformations. Furthermore, the biocatalytic reduction of 5-methyl-2,3-hexanedione to mainly 5-methyl-3-hydroxy-2-hexanone with only small amounts of 5-methyl-2-hydroxy-3-hexanone within an enzyme membrane reactor is demonstrated. Y1 - 2020 U6 - http://dx.doi.org/10.1039/D0RA02066D SN - 2046-2069 VL - 10 SP - 12206 EP - 12216 PB - Royal Society of Chemistry (RSC) CY - Cambridge ER - TY - JOUR A1 - Muschallik, Lukas A1 - Kipp, Carina Ronja A1 - Recker, Inga A1 - Bongaerts, Johannes A1 - Pohl, Martina A1 - Gelissen, Melanie A1 - Schöning, Michael Josef A1 - Selmer, Thorsten A1 - Siegert, Petra T1 - Synthesis of α-hydroxy ketones and vicinal diols with the Bacillus licheniformis DSM 13T butane-2, 3-diol dehydrogenase JF - Journal of Biotechnology N2 - The enantioselective synthesis of α-hydroxy ketones and vicinal diols is an intriguing field because of the broad applicability of these molecules. Although, butandiol dehydrogenases are known to play a key role in the production of 2,3-butandiol, their potential as biocatalysts is still not well studied. Here, we investigate the biocatalytic properties of the meso-butanediol dehydrogenase from Bacillus licheniformis DSM 13T (BlBDH). The encoding gene was cloned with an N-terminal StrepII-tag and recombinantly overexpressed in E. coli. BlBDH is highly active towards several non-physiological diketones and α-hydroxyketones with varying aliphatic chain lengths or even containing phenyl moieties. By adjusting the reaction parameters in biotransformations the formation of either the α-hydroxyketone intermediate or the diol can be controlled. Y1 - 2020 SN - 2590-1559 U6 - http://dx.doi.org/10.1016/j.jbiotec.2020.09.016 VL - 202 IS - Vol. 324 SP - 61 EP - 70 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Heiden, W. A1 - Turek, M. A1 - Schöning, Michael Josef T1 - TasteIT : Analyzing chemical sensor data using fuzzy logic Y1 - 2011 SN - 978-1-4244-9910-6 N1 - 2011 IEEE Workshop on Merging Fields of Computational Intelligence and Sensor Technology ; 11.-15. April 2011 Paris, France SP - 1 EP - 6 PB - IEEE CY - New York ER - TY - JOUR A1 - Mourzina, Y. A1 - Yoshinobu, T. A1 - Ermelenko, Y. A1 - Furuichi, K. A1 - Vlasov, Y. A1 - Schöning, Michael Josef A1 - Iwasaki, H. T1 - Technology of photocurable membranes for ion sensors based on laser scanned semiconductor transducer (LSST) JF - Book of abstracts / ed. by J. Saneistr. Y1 - 2002 SN - 80-01-02576-4 N1 - Eurosensors ; (16, 2002, Praha) SP - 254 EP - 257 PB - Czech Technical University, Faculty of Electrical Engineering, Department of Measurement CY - Prague ER - TY - JOUR A1 - Ermelenko, Y. A1 - Yoshinobu, T. A1 - Mourzina, Y. A1 - Furuichi, K. A1 - Iwasaki, H. A1 - Vlasov, Y. A1 - Schöning, Michael Josef T1 - Technology of photocurable polymeric membranes for integrated LAPS JF - Proceedings of the 5th East Asian Conference on Chemical Sensors; the 33rd Chemical Sensor Symposium : December 4 - 7, 2001, Huis Ten Bosch, Sasebo-shi, Nagasaki, Japan / Japan Association of Chemical Sensors; the Electrochemical Society of Japan Y1 - 2001 N1 - Chemical sensors; 17.2001 Suppl. B; East Asian Conference on Chemical Sensors ; (5, 2001; Nagasaki) SP - 66 EP - 68 PB - Japan Association of Chemical Sensors CY - Kasuga, Fukuoka-ken ER - TY - JOUR A1 - Ermelenko, Y. A1 - Yoshinobu, T. A1 - Mourzina, Y. A1 - Schöning, Michael Josef A1 - Furuichi, K. A1 - Levichev, S. A1 - Vlasov, Y. A1 - Iwasaki, H. T1 - The double K+/Ca2+ sensor based on laser scanned silicon transducer (LSST) for multicomponent analysis JF - Talanta. 59 (2003), H. 4 Y1 - 2003 SN - 0039-9140 SP - 785 EP - 795 ER - TY - JOUR A1 - Riemer, A. A1 - Schroth, P. A1 - Schütz, S. A1 - Hummel, Hans E. A1 - Lüth, H. A1 - Kohl, C.-D. A1 - Schöning, Michael Josef T1 - The future of fire detection: Biological sensors? – Die Zukunft der Brandgassensorik: Biologische Sensoren? JF - Gassensorik in der Brandmeldetechnik : [VdS-Fachtagung, am 15. und 16. November 2000 in Köln] = Gas sensors for fire detection / VdS Schadenverhütung Y1 - 2000 N1 - Fachtagung Gassensorik in der Brandmeldetechnik ; (2000, Köln) SP - 1 EP - 7 PB - VdS Schadenverhütung CY - Köln ER - TY - JOUR A1 - Polen, T. A1 - Krämer, Marco A1 - Bongaerts, Johannes A1 - Wubbolts, Marcel A1 - Wendisch, V. F. T1 - The global gene expression response of Escherichia coli to L-phenylalanine JF - Journal of biotechnology Y1 - 2005 SN - 1873-4863 (E-Journal); 0168-1656 (Print) VL - Vol. 115 IS - Iss. 3 SP - 221 EP - 237 ER - TY - JOUR A1 - Ermelenko, Y. A1 - Yoshinobu, T. A1 - Mourzina, Y. A1 - Schöning, Michael Josef A1 - Vlasov, Y. A1 - Iwasaki, H. T1 - The hybrid K+/Ca2+ sensor based on laser scanned silicon transducer for multi-component analysis JF - Proceedings of ICAS 2001, IUPAC [3rd] International Congress on Analytical Sciences 2001 : August 6 - 10, 2001, Waseda University, Tokyo Y1 - 2002 N1 - International Congress on Analytical Sciences <2001, Tokyo> ; International Union of Pure and Applied Chemistry. Pure and applied chemistry ; 73,10. ; Analytical sciences ; 17.2001, special issue SP - i777 EP - i780 PB - Japan Society for Analytical Chemistry CY - Tokyo ER - TY - JOUR A1 - Yoshinobu, T. A1 - Iwasaki, H. A1 - Ui, Y. A1 - Furuichi, K. A1 - Ermelenko, Y. A1 - Mourzina, Y. A1 - Wagner, Torsten A1 - Näther, Niko A1 - Schöning, Michael Josef T1 - The light-addressable potentiometric sensor for multi-ion sensing and imaging JF - Methods. 37 (2005), H. 1 Y1 - 2005 SN - 1046-2023 SP - 99 EP - 102 ER - TY - JOUR A1 - Voigt, Birgit A1 - Schroeter, Rebecca A1 - Jürgen, Britta A1 - Albrecht, Dirk A1 - Evers, Stefan A1 - Bongaerts, Johannes A1 - Maurer, Karl-Heinz A1 - Schweder, Thomas A1 - Hecker, Michael T1 - The response of Bacillus licheniformis to heat and ethanol stress and the role of the SigB regulon JF - Proteomics Y1 - 2013 SN - 1615-9861 (E-Journal); 1615-9853 (Print) VL - Vol. 13 IS - Iss. 14 SP - 2140 EP - 2146 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Schroth, P. A1 - Schütz, S. T1 - The use of insect chemoreceptors for the assembly of biosensors based on semiconductor field-effect sensors JF - Electroanalysis. 12 (2000), H. 9 Y1 - 2000 SN - 1040-0397 SP - 645 EP - 652 ER - TY - JOUR A1 - Guo, Yuanyuan A1 - Miyamoto, Ko-ichiro A1 - Wagner, Torsten A1 - Schöning, Michael Josef A1 - Yoshinobu, Tatsuo T1 - Theoretical study and simulation of light-addressable potentiometric sensors JF - Physica status solidi (A) : applications and materials N2 - The light-addressable potentiometric sensor (LAPS) is a semiconductor-based potentiometric sensor using a light probe with an ability of detecting the concentration of biochemical species in a spatially resolved manner. As an important biomedical sensor, research has been conducted to improve its performance, for instance, to realize high-speed measurement. In this work, the idea of facilitating the device-level simulation, instead of using an equivalent-circuit model, is presented for detailed analysis and optimization of the performance of the LAPS. Both carrier distribution and photocurrent response have been simulated to provide new insight into both amplitude-mode and phase-mode operations of the LAPS. Various device parameters can be examined to effectively design and optimize the LAPS structures and setups for enhanced performance. Y1 - 2014 U6 - http://dx.doi.org/10.1002/pssa.201330354 SN - 0031-8965 VL - 211 IS - 6 SP - 1467 EP - 1472 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Oberländer, Jan A1 - Kirchner, Patrick A1 - Wagner, Patrick H. A1 - Schöning, Michael Josef T1 - Thermocatalytic Behavior of Manganese (IV) Oxide as Nanoporous Material on the Dissociation of a Gas Mixture Containing Hydrogen Peroxide JF - Nanomaterials N2 - In this article, we present an overview on the thermocatalytic reaction of hydrogen peroxide (H₂O₂) gas on a manganese (IV) oxide (MnO₂) catalytic structure. The principle of operation and manufacturing techniques are introduced for a calorimetric H₂O₂ gas sensor based on porous MnO₂. Results from surface analyses by X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM) of the catalytic material provide indication of the H₂O₂ dissociation reaction schemes. The correlation between theory and the experiments is documented in numerical models of the catalytic reaction. The aim of the numerical models is to provide further information on the reaction kinetics and performance enhancement of the porous MnO₂ catalyst. Y1 - 2018 U6 - http://dx.doi.org/10.3390/nano8040262 SN - 2079-4991 VL - 8 IS - 4 PB - MDPI CY - Basel ER - TY - JOUR A1 - Mourzina, Y. G. A1 - Legin, A. A1 - Vlasov, Y. G. A1 - Schöning, Michael Josef A1 - Schubert, J. A1 - Zander, W. A1 - Lüth, H. T1 - Thin film chemical sensors based on chalcogenide glasses for „electronic tongue“ applications JF - Sensor 2001 : 10th international conference, May 8 - 10, 2001, Exhibition Centre Nuremberg, Germany ; proceedings Y1 - 2001 N1 - Sensor-Kongress ; (10, 2001, Nürnberg) Sensor 2001 Conference ; (10 : ; 2001.05.08-10 : ; Nuremberg) SP - 137 EP - 141 PB - AMA Service CY - Wunstorf ER - TY - JOUR A1 - Mourzina, Yu.G. A1 - Schöning, Michael Josef A1 - Schubert, J. A1 - Zander, W. A1 - Legin, A. A1 - Vlasov, Y. G. A1 - Lüth, H. T1 - Thin film microsensors for fast heavy metal analysis JF - Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...] Y1 - 2000 SN - 87-89935-50-0 N1 - Eurosensors ; (14, 2000, København) ; Eurosensors ; (14 : ; 2000.08.27-30 : ; Copenhagen) ; European Conference on Solid-State Transducers ; (14 : ; 2000.08.27-30 : ; Copenhagen) SP - 839 EP - 840 PB - MIC, Mikroelektronik Centret CY - Lyngby, Denmark ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Schmidt, C. A1 - Schubert, J. A1 - Zander, W. A1 - Mesters, S. A1 - Kordos, P. A1 - Lüth, H. A1 - Legin, A. A1 - Seleznev, B. A1 - Vlasov, Y. G. T1 - Thin film sensors on the basis of chalcogenide glass materials prepared by pulsed laser deposition technique JF - Sensors and Actuators B. 68 (2000), H. 1-3 Y1 - 2000 SN - 0925-4005 SP - 254 EP - 259 ER - TY - CHAP A1 - Yoshinobu, T. A1 - Schöning, Michael Josef A1 - Finger, F. A1 - Moritz, W. A1 - Iwasaki, H. T1 - Thin-film a-Si LAPS : Preparation and pH sensitivity T2 - Eurosensors XVII : the 17th European Conference on Solid-State Transducers ; University of Minho, Guimarães, Portugal, September 21 - 24, 2003 Y1 - 2003 SP - 88 EP - 89 ER - TY - JOUR A1 - Kirchner, Patrick A1 - Li, B. A1 - Spelthahn, H. A1 - Henkel, H. A1 - Friedrich, P. A1 - Kolstad, J. A1 - Keusgen, M. A1 - Schöning, Michael Josef T1 - Thin-film calorimetric H2O2 gas sensor for the validation of germicidal effectivity in aseptic filling processes JF - Procedia Chemistry. 1 (2009), H. 1 Y1 - 2009 SN - 1876-6196 N1 - Proceedings of the Eurosensors XXIII conference ; Eurosensors 23 SP - 983 EP - 986 ER - TY - JOUR A1 - Kirchner, Patrick A1 - Li, Bin A1 - Spelthahn, Heiko A1 - Henkel, Hartmut A1 - Schneider, Andreas A1 - Friedrich, Peter A1 - Kolstad, Jens A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Thin-film calorimetric H2O2 gas sensor for the validation of germicidal effectivity in aseptic filling processes JF - Sensors and Actuators B: Chemical. 154 (2011), H. 2 Y1 - 2011 SN - 1873-3077 N1 - EUROSENSORS XXIII SP - 257 EP - 263 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Kloock, Joachim P. A1 - Schubert, J. A1 - Ermelenko, Y. A1 - Vlasov, Y. G. A1 - Bratov, A. A1 - Schöning, Michael Josef T1 - Thin-film sensors with chalcogenide glass materials – a general survey T2 - Biochemical sensing utilisation of micro- and nanotechnologies : Warsaw, [23rd - 26th] November 2005 / ed. by M. Mascini ... Y1 - 2006 SP - 92 EP - 97 CY - Warsaw ER - TY - CHAP A1 - Koch, Claudia A1 - Poghossian, Arshak A1 - Wege, Christina A1 - Schöning, Michael Josef ED - Wege, Christina T1 - TMV-Based Adapter Templates for Enhanced Enzyme Loading in Biosensor Applications T2 - Virus-Derived Nanoparticles for Advanced Technologies N2 - Nanotubular tobacco mosaic virus (TMV) particles and RNA-free lower-order coat protein (CP) aggregates have been employed as enzyme carriers in different diagnostic layouts and compared for their influence on biosensor performance. In the following, we describe a label-free electrochemical biosensor for improved glucose detection by use of TMV adapters and the enzyme glucose oxidase (GOD). A specific and efficient immobilization of streptavidin-conjugated GOD ([SA]-GOD) complexes on biotinylated TMV nanotubes or CP aggregates was achieved via bioaffinity binding. Glucose sensors with adsorptively immobilized [SA]-GOD, and with [SA]-GOD cross-linked with glutardialdehyde, respectively, were tested in parallel on the same sensor chip. Comparison of these sensors revealed that TMV adapters enhanced the amperometric glucose detection remarkably, conveying highest sensitivity, an extended linear detection range and fastest response times. These results underline a great potential of an integration of virus/biomolecule hybrids with electronic transducers for applications in biosensorics and biochips. Here, we describe the fabrication and use of amperometric sensor chips combining an array of circular Pt electrodes, their loading with GOD-modified TMV nanotubes (and other GOD immobilization methods), and the subsequent investigations of the sensor performance. KW - Tobacco mosaic virus (TMV) KW - Coat protein KW - Enzyme nanocarrier KW - Glucose biosensor KW - Glucose oxidase Y1 - 2018 SN - 978-1-4939-7808-3 U6 - http://dx.doi.org/10.1007/978-1-4939-7808-3 N1 - Methods in Molecular Biology, vol 1776 SP - 553 EP - 568 PB - Humana Press CY - New York, NY ER - TY - JOUR A1 - Bäcker, Matthias A1 - Koch, Claudia A1 - Eiben, Sabine A1 - Geiger, Fania A1 - Eber, Fabian A1 - Gliemann, Hartmut A1 - Poghossian, Arshak A1 - Wege, Christina A1 - Schöning, Michael Josef T1 - Tobacco mosaic virus as enzyme nanocarrier for electrochemical biosensors JF - Sensors and Actuators B: Chemical N2 - The conjunction of (bio-)chemical recognition elements with nanoscale biological building blocks such as virus particles is considered as a very promising strategy for the creation of biohybrids opening novel opportunities for label-free biosensing. This work presents a new approach for the development of biosensors using tobacco mosaic virus (TMV) nanotubes or coat proteins (CPs) as enzyme nanocarriers. Sensor chips combining an array of Pt electrodes loaded with glucose oxidase (GOD)-modified TMV nanotubes or CP aggregates were used for amperometric detection of glucose as a model system for the first time. The presence of TMV nanotubes or CPs on the sensor surface allows binding of a high amount of precisely positioned enzymes without substantial loss of their activity, and may also ensure accessibility of their active centers for analyte molecules. Specific and efficient immobilization of streptavidin-conjugated GOD ([SA]-GOD) complexes on biotinylated TMV nanotubes or CPs was achieved via bioaffinity binding. These layouts were tested in parallel with glucose sensors with adsorptively immobilized [SA]-GOD, as well as [SA]-GOD crosslinked with glutardialdehyde, and came out to exhibit superior sensor performance. The achieved results underline a great potential of an integration of virus/biomolecule hybrids with electronic transducers for future applications in biosensorics and biochips. Y1 - 2017 U6 - http://dx.doi.org/10.1016/j.snb.2016.07.096 SN - 0925-4005 VL - 238 SP - 716 EP - 722 PB - Elsevier CY - Amsterdam ER -