TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Lüth, H.
T1  - Novel concepts for silicon-based biosensors
JF  - Physica Status Solidi (A) (2001)
Y1  - 2001
SN  - 0031-8965
SP  - 65
EP  - 77
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Malkoc, Ü.
A1  - Thust, M.
A1  - Steffen, A.
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Novel electrochemical sensors with structured and porous semiconductor/insulator capacitors
JF  - Sensors and Actuators B. 65 (2000), H. 1-3
Y1  - 2000
SN  - 0925-4005
SP  - 288
EP  - 290
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Malkoc, Ü.
A1  - Thust, M.
A1  - Steffen, A.
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Novel electrochemical sensors with structured and porous semiconductor/insulator capacitors
JF  - Proceedings of the Seventh International Meeting on Chemical Sensors : 27 - 30 July, 1998, Beijing, P. R. China / ed. Zhi-Gang Zhou
Y1  - 1998
N1  - International Meeting on Chemical Sensors ; (7, 1998, Beijing) ; International Meeting on Chemical Sensors (IMCS) ; (7 : ; 1998.07.27-30 : ; Beijing)
SP  - 885
EP  - 887
PB  - Elsevier
CY  - Amsterdam [u.a.]
ER  - 
TY  - JOUR
A1  - Selmer, Thorsten
A1  - Jennemann, Richard
A1  - Bauer, Bernhard L.
A1  - Bertalanffy, Helmut
T1  - Novel glycoinositolphosphosphingolipids, basidiolipids, from Agaricus / Jennemann, Richard ; Bauer, Bernhard, L. ; Bertalanffy, Helmut ; Geyer, Rudolf ; Gschwind, Ruth, M. ; Selmer, Thorsten ; Wiegandt, Herbert
JF  - European Journal of Biochemistry. 259 (1999), H. 1-2
Y1  - 1999
SN  - 0014-2956
SP  - 331
EP  - 338
ER  - 
TY  - JOUR
A1  - Förster, Arnold
A1  - Lachenmann, S. G.
A1  - Kastalsky, A.
T1  - Novel hybrid Nb/InAs/Nb step junctions / S. G. Lachenmann ; A. Kastalsky ; I. Friedrich ; A. Förster ...
JF  - Czechoslovak journal of physics . 46 (1996), H. S2
Y1  - 1996
SN  - 0011-4626
SP  - 659
ER  - 
TY  - JOUR
A1  - Guo, Yuanyuan
A1  - Seki, Kosuke
A1  - Miyamoto, Ko-ichiro
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Yoshinobu, Tatsuo
T1  - Novel photoexcitation method for light-addressable potentiometric sensor with higher spatial resolution
JF  - Applied physics express : APEX
N2  - A novel photoexcitation method for the light-addressable potentiometric sensor (LAPS) is proposed to achieve a higher spatial resolution of chemical images. The proposed method employs a combined light source that consists of a modulated light probe, which generates the alternating photocurrent signal, and a ring of constant illumination surrounding it. The constant illumination generates a sheath of carriers with increased concentration which suppresses the spread of photocarriers by enhanced recombination. A device simulation was carried out to verify the effect of constant illumination on the spatial resolution, which demonstrated that a higher spatial resolution can be obtained.
Y1  - 2014
U6  - https://doi.org/10.7567/APEX.7.067301
SN  - 1882-0786 (E-Journa); 1882-0778 (Print)
VL  - 7
IS  - 6
SP  - 067301-4
PB  - IOP
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Seiler, Friedrich
A1  - Pichler, Alexander
A1  - Pfaff, Raphael
A1  - Srulijes, Julio
T1  - Novel processing tools for automated doppler picture velocimetry (DPV) evaluation
JF  - Journal of visualization
Y1  - 2009
SN  - 1343-8875
VL  - Vol. 12
IS  - Iss. 4
SP  - 323
EP  - 337
ER  - 
TY  - JOUR
A1  - Haeger, Gerrit
A1  - Jolmes, Tristan
A1  - Oyen, Sven
A1  - Jaeger, Karl-Erich
A1  - Bongaerts, Johannes
A1  - Schörken, Ulrich
A1  - Siegert, Petra
T1  - Novel recombinant aminoacylase from Paraburkholderia monticola capable of N-acyl-amino acid synthesis
JF  - Applied Microbiology and Biotechnology
N2  - N-Acyl-amino acids can act as mild biobased surfactants, which are used, e.g., in baby shampoos. However, their chemical synthesis needs acyl chlorides and does not meet sustainability criteria. Thus, the identification of biocatalysts to develop greener synthesis routes is desirable. We describe a novel aminoacylase from Paraburkholderia monticola DSM 100849 (PmAcy) which was identified, cloned, and evaluated for its N-acyl-amino acid synthesis potential. Soluble protein was obtained by expression in lactose autoinduction medium and co-expression of molecular chaperones GroEL/S. Strep-tag affinity purification enriched the enzyme 16-fold and yielded 15 mg pure enzyme from 100 mL of culture. Biochemical characterization revealed that PmAcy possesses beneficial traits for industrial application like high temperature and pH-stability. A heat activation of PmAcy was observed upon incubation at temperatures up to 80 °C. Hydrolytic activity of PmAcy was detected with several N-acyl-amino acids as substrates and exhibited the highest conversion rate of 773 U/mg with N-lauroyl-L-alanine at 75 °C. The enzyme preferred long-chain acyl-amino-acids and displayed hardly any activity with acetyl-amino acids. PmAcy was also capable of N-acyl-amino acid synthesis with good conversion rates. The best synthesis results were obtained with the cationic L-amino acids L-arginine and L-lysine as well as with L-leucine and L-phenylalanine. Exemplarily, L-phenylalanine was acylated with fatty acids of chain lengths from C8 to C18 with conversion rates of up to 75%. N-lauroyl-L-phenylalanine was purified by precipitation, and the structure of the reaction product was verified by LC–MS and NMR.
KW  - Chaperone
KW  - Biocatalysis
KW  - Aminoacylase
KW  - Acylation
KW  - Acyl-amino acids
KW  - Biosurfactants
Y1  - 2024
U6  - https://doi.org/10.1007/s00253-023-12868-8
SN  - 1432-0614
N1  - Corresponding author: Petra Siegert
IS  - 108
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Heuermann, Holger
A1  - Erkens, H.
T1  - Novel RF switch concepts for differential wireless communications frontends. Erkens, H.; Heuermann, H.
JF  - IEEE Transactions on Microwave Theory and Techniques. 54 (2006), H. 6, Part 1
Y1  - 2006
SN  - 0018-9480
SP  - 2376
EP  - 2382
ER  - 
TY  - JOUR
A1  - Heuermann, Holger
A1  - Ibrahim, Irfan
T1  - Novel theory and architecture of a vector signal generator implemented with two PLLs / Ibrahim, Irfan ; Heuermann, Holger
JF  - European Conference on Wireless Technology, 2008. EuWiT 2008.
Y1  - 2008
SN  - 978-2-87487-008-8
SP  - 85
EP  - 88
ER  - 
TY  - JOUR
A1  - Iken, Heiko
A1  - Kirsanov, D.
A1  - Legin, A.
A1  - Schöning, Michael Josef
T1  - Novel Thin-Film Polymeric Materials for the Detection of Heavy Metals
JF  - Procedia Engineering
N2  - A variety of transition metals, e.g., copper, zinc, cadmium, lead, etc. are widely used in industry as components for wires, coatings, alloys, batteries, paints and so on. The inevitable presence of transition metals in industrial processes implies the ambition of developing a proper analytical technique for their adequate monitoring. Most of these elements, especially lead and cadmium, are acutely toxic for biological organisms. Quantitative determination of these metals at low activity levels in different environmental and industrial samples is therefore a vital task. A promising approach to achieve an at-side or on-line monitoring on a miniaturized and cost efficient way is the combination of a common potentiometric sensor array with heavy metal-sensitive thin-film materials, like chalcogenide glasses and polymeric materials, respectively.
Y1  - 2012
U6  - https://doi.org/10.1016/j.proeng.2012.09.148
SN  - 1877-7058
N1  - Part of special issue "26th European Conference on Solid-State Transducers, EUROSENSOR 2012"
IS  - 47
SP  - 322
EP  - 325
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Heuermann, Holger
A1  - Thalayasingam, K.
T1  - Novel vector non-linear measurement system for intermodulation measurements  / Thalayasingam, K.; Heuermann, H.
JF  - European Microwave Conference, 2009 : EuMC 2009 ; Sept. 29, 2009 - Oct. 1, 2009, Rome, Italy ; part of European Microwave Week (EuMW) / sponsored by EuMA, European Microwave Association ... Endorsed by IEEE
Y1  - 2009
SN  - 978-1-4244-4748-0
N1  - European Microwave Conference ; (39 : ; 2009.09.29-10.01 : ; Rome)
SP  - 926
EP  - 929
PB  - IEEE
CY  - Piscataway, NJ
ER  - 
TY  - JOUR
A1  - Monakhova, Yulia
A1  - Diehl, Bernd W.K.
T1  - Nuclear magnetic resonance spectroscopy as an elegant tool for a complete quality control of crude heparin material
JF  - Journal of Pharmaceutical and Biomedical Analysis
N2  - Nuclear magnetic resonance (NMR) spectrometric methods for the quantitative analysis of pure heparin in crude heparin is proposed. For quantification, a two-step routine was developed using a USP heparin reference sample for calibration and benzoic acid as an internal standard. The method was successfully validated for its accuracy, reproducibility, and precision. The methodology was used to analyze 20 authentic porcine heparinoid samples having heparin content between 4.25 w/w % and 64.4 w/w %. The characterization of crude heparin products was further extended to a simultaneous analysis of these common ions: sodium, calcium, acetate and chloride. A significant, linear dependence was found between anticoagulant activity and assayed heparin content for thirteen heparinoids samples, for which reference data were available. A Diffused-ordered NMR experiment (DOSY) can be used for qualitative analysis of specific glycosaminoglycans (GAGs) in heparinoid matrices and, potentially, for quantitative prediction of molecular weight of GAGs. NMR spectrometry therefore represents a unique analytical method suitable for the simultaneous quantitative control of organic and inorganic composition of crude heparin samples (especially heparin content) as well as an estimation of other physical and quality parameters (molecular weight, animal origin and activity).
KW  - NMR spectroscopy
KW  - Heparin
KW  - Crude heparin
KW  - USP
KW  - Ions
Y1  - 2022
U6  - https://doi.org/10.1016/j.jpba.2022.114915
SN  - 0731-7085
VL  - 219
IS  - Article number: 114915
PB  - Elsevier
CY  - New York, NY
ER  - 
TY  - JOUR
A1  - Stanley, Lesley A.
A1  - Horsburgh, Brian C.
A1  - Ross, Jillian
A1  - Scheer, Nico
A1  - Wolf, C. Roland
T1  - Nuclear Receptors which play a pivotal role in drug disposition and chemical toxicity
JF  - Drug Metabolism Reviews
Y1  - 2006
U6  - https://doi.org/10.1080/03602530600786232
SN  - 1097-9883
VL  - 38
IS  - 3
SP  - 515
EP  - 597
ER  - 
TY  - JOUR
A1  - Hoyler, Friedrich
A1  - Hoff, R. W.
A1  - Börner, H. G.
T1  - Nuclear structure of 170Tm from neutron-capture and (d,p)-reaction measurements / R. W. Hoff ; H. G. Börner ... F. Hoyler ...
JF  - Physical review / C. 54 (1996), H. 1
Y1  - 1996
SN  - 0556-2813
SP  - 78
EP  - 116
ER  - 
TY  - JOUR
A1  - Hoyler, Friedrich
A1  - White, D.H.
A1  - Hoff, R. W.
T1  - Nuclear structure of 241Pu from neutron-capture, (d,p)-, and (d,t)-reaction measurements / D. H. White ; R. W. Hoff ... F. Hoyler ...
JF  - Physical review / C. 57 (1998), H. 3
Y1  - 1998
SN  - 0556-2813
SP  - 1112
EP  - 1133
ER  - 
TY  - JOUR
A1  - Grajewski, Matthias
A1  - Köster, Michael
A1  - Turek, Stefam
T1  - Numerical analysis and implementational aspects of a new multilevel grid deformation method
JF  - Applied Numerical Mathematics
N2  - Recently, we introduced and mathematically analysed a new method for grid deformation (Grajewski et al., 2009) [15] we call basic deformation method (BDM) here. It generalises the method proposed by Liao et al. (Bochev et al., 1996; Cai et al., 2004; Liao and Anderson, 1992) [4], [6], [20]. In this article, we employ the BDM as core of a new multilevel deformation method (MDM) which leads to vast improvements regarding robustness, accuracy and speed. We achieve this by splitting up the deformation process in a sequence of easier subproblems and by exploiting grid hierarchy. Being of optimal asymptotic complexity, we experience speed-ups up to a factor of 15 in our test cases compared to the BDM. This gives our MDM the potential for tackling large grids and time-dependent problems, where possibly the grid must be dynamically deformed once per time step according to the user's needs. Moreover, we elaborate on implementational aspects, in particular efficient grid searching, which is a key ingredient of the BDM.
Y1  - 2010
U6  - https://doi.org/10.1016/j.apnum.2010.03.017
SN  - 0168-9274
VL  - 60
IS  - 8
SP  - 767
EP  - 781
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Grajewski, Matthias
A1  - Hron, Jaroslav
A1  - Turek, Stefan
T1  - Numerical analysis for a new non-conforming linear finite element on quadrilaterals
JF  - Journal of Computational and Applied Mathematics
Y1  - 2006
U6  - https://doi.org/10.1016/j.cam.2005.05.024
SN  - 0377-0427
VL  - 193
IS  - 1
SP  - 38
EP  - 50
ER  - 
TY  - JOUR
A1  - Marinkovic, Marko
A1  - Butenweg, Christoph
T1  - Numerical analysis of the in-plane behaviour of decoupled masonry infilled RC frames
JF  - Engineering Structures
N2  - Damage of reinforced concrete (RC) frames with masonry infill walls has been observed after many earthquakes. Brittle behaviour of the masonry infills in combination with the ductile behaviour of the RC frames makes infill walls prone to damage during earthquakes. Interstory deformations lead to an interaction between the infill and the RC frame, which affects the structural response. The result of this interaction is significant damage to the infill wall and sometimes to the surrounding structural system too. In most design codes, infill walls are considered as non-structural elements and neglected in the design process, because taking into account the infills and considering the interaction between frame and infill in software packages can be complicated and impractical. A good way to avoid negative aspects arising from this behavior is to ensure no or low-interaction of the frame and infill wall, for instance by decoupling the infill from the frame. This paper presents the numerical study performed to investigate new connection system called INODIS (Innovative Decoupled Infill System) for decoupling infill walls from surrounding frame with the aim to postpone infill activation to high interstory drifts thus reducing infill/frame interaction and minimizing damage to both infills and frames. The experimental results are first used for calibration and validation of the numerical model, which is then employed for investigating the influence of the material parameters as well as infill’s and frame’s geometry on the in-plane behaviour of the infilled frames with the INODIS system. For all the investigated situations, simulation results show significant improvements in behaviour for decoupled infilled RC frames in comparison to the traditionally infilled frames.
KW  - Seismic loading
KW  - Earthquake
KW  - In-plane performance, isolation
KW  - Infill wall design
KW  - Numerical modelling
Y1  - 2022
U6  - https://doi.org/10.1016/j.engstruct.2022.114959
SN  - 0141-0296
VL  - 272
IS  - 1
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Funke, Harald
A1  - Beckmann, Nils
A1  - Keinz, Jan
A1  - Abanteriba, Sylvester
T1  - Numerical and Experimental Evaluation of a Dual-Fuel Dry-Low-NOx Micromix Combustor for Industrial Gas Turbine Applications
JF  - Journal of Thermal Science and Engineering Applications
Y1  - 2019
U6  - https://doi.org/10.1115/1.4041495
SN  - 19485085
N1  - Paper No: GT2017-64795
VL  - 11
IS  - 1
SP  - 011015
PB  - ASME
CY  - New York
ER  - 
TY  - JOUR
A1  - Robinson, A. E.
A1  - Funke, Harald
A1  - Wagemakers, R.
A1  - Grossen, J.
A1  - Bosschaerts, W.
A1  - Hendrick, P.
T1  - Numerical and Experimental Investigation of a Micromix Combustor for a Hydrogen Fuelled μ-Scale Gas Turbine
JF  - Proceedings of the ASME Turbo Expo 2009 : : presented at the 2009 ASME Turbo Expo, June 8 - 12, 2009, Orlando, Florida, USA / sponsored by the International Gas Turbine Institute
Y1  - 2009
SN  - 9780791848869
N1  - GT2009-60061
SP  - 253
EP  - 262
PB  - ASME
CY  - New York, NY
ER  - 
TY  - JOUR
A1  - Reisgen, Uwe
A1  - Schleser, Markus
A1  - Mokrov, Oleg
A1  - Ahmed, Essam
T1  - Numerical and experimental investigation of tensile behavior of laser beam welded TRIP700 steel
JF  - ISIJ international
Y1  - 2011
SN  - 1347-5460 (E-Journal); 0915-1559 (Print)
VL  - Vol. 51
IS  - No. 3
SP  - 429
EP  - 434
PB  - ISIJ
CY  - Tōkyō
ER  - 
TY  - JOUR
A1  - Bohn, Dieter
A1  - Funke, Harald
A1  - Heuer, Tom
A1  - Bütikofer, J.
T1  - Numerical and experimental investigations of the influence of different swirl-ratios on the temperature streak equalization in a 4-stage turbine
JF  - ASME Turbo Expo 2000 ; Munich, May 8-11 2000
Y1  - 2000
N1  - ASME-paper ; 2000-GT-250
CY  - Munich
ER  - 
TY  - JOUR
A1  - Bohn, Dieter
A1  - Funke, Harald
A1  - Sürken, Norbert
A1  - Kreitmeier, F.
T1  - Numerical and experimental investigations on endwall contouring in a four-stage turbine
JF  - ASME Turbo Expo Land Sea & Air 2001 : June 4 - 8, 2001, New Orleans, Louisiana / IGTI, International Gas Turbine Institute. American Society of Mechanical Engineers. International Gas Turbine Institute ..
Y1  - 2001
SN  - 0-7918-3528-6
N1  - ASME-Paper 2001-GT-0481
PB  - ASME
CY  - New York, NY
ER  - 
TY  - JOUR
A1  - Bohn, D.
A1  - Funke, Harald
A1  - Gier, J.
T1  - Numerical and Experimental Investigations on the Flow in a 4-Stage Turbine with Special Focus on the Development of a Radial Temperature Streak
JF  - ASME Turbo Expo 1999, Indianapolis, USA, 1999
Y1  - 1999
N1  - ASME-Paper 99-GT-027
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Mai, A.
A1  - Waluga, C.
A1  - Bergmann, B.
A1  - Tran, L.
A1  - Vonderstein, K.
A1  - Behr, M.
A1  - Mottaghy, K.
T1  - Numerical Modeling of Flow-Related Thrombus Formation under Physiological and Non-Physiological Flow Conditions
JF  - Acta Physiologica
Y1  - 2010
SN  - 1748-1716
N1  - Joint Congress of the Scandinavian and German Physiological Societies, Copenhagen, Denmark, March 27-30, 2010
VL  - 198
IS  - Supplement 677
SP  - 185
ER  - 
TY  - JOUR
A1  - Zastrow, Udo
T1  - Numerical plane stress analysis by integral equations based on the singularity method
JF  - SM archives . 10 (1985)
Y1  - 1985
SN  - 0376-7426
SP  - 113
EP  - 128
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Probst, M.
A1  - Mai, A.
A1  - Behr, M.
A1  - Tran, L.
A1  - Vonderstein, K.
A1  - Mottaghy, K.
T1  - Numerical Prediction of Blood Damage in Biomedical Devices
Y1  - 2010
N1  - Posterpresentation ; Biomedica Congress, Aachen, March 17-18, 2010
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Tran, L.
A1  - Jockenhövel, S.
A1  - Behr, M.
A1  - Mottaghy, K.
T1  - Numerical prediction of thrombocyte reactions for application to a vascular flow model
JF  - British Journal of Surgery
Y1  - 2011
SN  - 1365-2168
N1  - 46th Congress of the European Society for Surgical Research, Aachen, Germany, 25-28 May 2011 ; ESSR Abstracts 2011 ; Oral Sessions OP10-5
VL  - 98
IS  - S5
SP  - S17
PB  - Oxford University Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Edip, Kemal
A1  - Garevski, Mihail
A1  - Butenweg, Christoph
A1  - Sesov, Vlatko
A1  - Cvetanovska, Julijana
A1  - Gjorgiev, Igor
T1  - Numerical simulation of geotechnical problems by coupled finite and infinite elements
JF  - Journal of civil engineering and architecture
Y1  - 2013
SN  - 1934-7359 (E-Journal)
VL  - 7
IS  - 1
SP  - 68
EP  - 77
PB  - David Publishing
CY  - Libertyville
ER  - 
TY  - JOUR
A1  - Valero, Daniel
A1  - Viti, Nicolo
A1  - Gualtieri, Carlo
T1  - Numerical Simulation of Hydraulic Jumps. Part 1: Experimental Data for Modelling Performance Assessment
JF  - Water
Y1  - 2019
U6  - https://doi.org/10.3390/w11010036
SN  - 2073-4441
VL  - 11
IS  - 1
SP  - Art. Nr. 36
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Viti, Nicolo
A1  - Valero, Daniel
A1  - Gualtieri, Carlo
T1  - Numerical Simulation of Hydraulic Jumps. Part 2: Recent Results and Future Outlook
JF  - Water
Y1  - 2019
U6  - https://doi.org/10.3390/w11010028
SN  - 2073-4441
VL  - 11
IS  - 1
SP  - Art. Nr. 28
ER  - 
TY  - JOUR
A1  - Helsper, Christoph
A1  - Fißan, H. J.
T1  - Numerical Simulation Studies and Data Reduction for Size Classifying Measurement Techniques / Fißan, H. J.; Helsper, C.
JF  - Aerosols in science, medicine and technology : conference / Gesellschaft für Aerosolforschung 7. 1979.
Y1  - 1979
SP  - 199
EP  - 205
ER  - 
TY  - JOUR
A1  - Helsper, Christoph
A1  - Fißan, H. J.
T1  - Numerical Simulation Studies and Data Reduction for Size Classifying Measurement Techniques / Fißan, H. J.; Helsper, C.
JF  - Advances in Particle Sampling and Measurement: Proceedings, Daytona Beach, EPA 600/9 80 004, 1980
Y1  - 1980
N1  - Advances in Particle Sampling and Measurement ; (1979.10. : ; Daytona Beach/Fla.)
PB  - National Technical Information Service
CY  - Springfield, Va.
ER  - 
TY  - JOUR
A1  - Pieper, Martin
A1  - Klein, Peter
T1  - Numerical solution of the heat equation with non-linear, time derivative-dependent source term
JF  - International Journal for Numerical Methods in Engineering
N2  - The mathematical modeling of heat conduction with adsorption effects in coated metal structures yields the heat equation with piecewise smooth coefficients and a new kind of source term. This term is special, because it is non-linear and furthermore depends on a time derivative. In our approach we reformulated this as a new problem for the usual heat equation, without source term but with a new non-linear coefficient. We gave an existence and uniqueness proof for the weak solution of the reformulated problem. To obtain a numerical solution, we developed a semi-implicit and a fully implicit finite volume method. We compared these two methods theoretically as well as numerically. Finally, as practical application, we simulated the heat conduction in coated aluminum fibers with adsorption in the zeolite coating. Copyright © 2010 John Wiley & Sons, Ltd.
Y1  - 2010
U6  - https://doi.org/10.1002/nme.2937
SN  - 0029-5981
VL  - 84
IS  - 10
SP  - 1205
EP  - 1221
PB  - Wiley
CY  - Chichester
ER  - 
TY  - JOUR
A1  - Werner, Frederik
A1  - Groebel, Simone
A1  - Krumbe, Christoph
A1  - Wagner, Torsten
A1  - Selmer, Thorsten
A1  - Yoshinobu, Tatsuo
A1  - Baumann, Marcus
A1  - Schöning, Michael Josef
T1  - Nutrient concentration-sensitive microorganism-based biosensor
JF  - Physica Status Solidi (a)
Y1  - 2012
U6  - https://doi.org/10.1002/pssa.201100801
SN  - 1862-6319
VL  - 209
IS  - 5
SP  - 900
EP  - 904
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Unden, G.
A1  - Becker, S.
A1  - Bongaerts, Johannes
A1  - Holighaus, G.
A1  - Schirawski, J.
A1  - Six, S.
T1  - O2-sensing and O2-dependent gene regulation in facultatively anaerobic bacteria
JF  - Archives of microbiology
Y1  - 1995
SN  - 1432-072X (E-Journal); 0003-9276 (Print); 0302-8933 (Print)
VL  - Vol. 164
IS  - Iss. 2
SP  - 81
EP  - 90
ER  - 
TY  - JOUR
A1  - Kornfeld, Jan-Wilhelm
A1  - Baitzel, Catherina
A1  - Könner, A. Christine
A1  - Nicholls, Hayley T.
A1  - Vogt, Merly C.
A1  - Herrmanns, Karolin
A1  - Scheja, Ludger
A1  - Haumaitre, Cécile
A1  - Wolf, Anna M.
A1  - Knippschild, Uwe
A1  - Seibler, Jost
A1  - Cereghini, Silvia
A1  - Heeren, Joerg
A1  - Stoffel, Markus
A1  - Brüning, Jens C.
T1  - Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b
JF  - Nature
Y1  - 2013
SN  - 0028-0836
U6  - https://doi.org/10.1038/nature11793
VL  - 494
IS  - 7435
SP  - 111
EP  - 115
PB  - Springer Nature
CY  - Cham
ER  - 
TY  - JOUR
A1  - Jordan, Sabine D.
A1  - Krüger, Markus
A1  - Willmes, Diana M.
A1  - Redemann, Nora
A1  - Wunderlich, F. Thomas
A1  - Brönneke, Hella S.
A1  - Merkwirth, Carsten
A1  - Kashkar, Hamid
A1  - Olkkonen, Vesa M.
A1  - Böttger, Thomas
A1  - Braun, Thomas
A1  - Seibler, Jost
A1  - Brüning, Jens C.
T1  - Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism
JF  - Nature Cell Biology
N2  - The contribution of altered post-transcriptional gene silencing to the development of insulin resistance and type 2 diabetes mellitus so far remains elusive. Here, we demonstrate that expression of microRNA (miR)-143 and 145 is upregulated in the liver of genetic and dietary mouse models of obesity. Induced transgenic overexpression of miR-143, but not miR-145, impairs insulin-stimulated AKT activation and glucose homeostasis. Conversely, mice deficient for the miR-143–145 cluster are protected from the development of obesity-associated insulin resistance. Quantitative-mass-spectrometry-based analysis of hepatic protein expression in miR-143-overexpressing mice revealed miR-143-dependent downregulation of oxysterol-binding-protein-related protein (ORP) 8. Reduced ORP8 expression in cultured liver cells impairs the ability of insulin to induce AKT activation, revealing an ORP8-dependent mechanism of AKT regulation. Our experiments provide direct evidence that dysregulated post-transcriptional gene silencing contributes to the development of obesity-induced insulin resistance, and characterize the miR-143–ORP8 pathway as a potential target for the treatment of obesity-associated diabetes.
Y1  - 2011
U6  - https://doi.org/10.1038/ncb2211
SN  - 1465-7392
VL  - 13
IS  - 4
SP  - 434
EP  - 446
PB  - Nature
CY  - New York
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Lieder, R. M.
A1  - Didelez, J. P.
A1  - Beuscher, H.
T1  - Observation of a New Isomer in ²¹² Po
JF  - Annual report 1978 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: A. Fässler. -
Y1  - 1979
N1  - Spezielle Berichte der Kernforschungsanlage Jülich ; 36
SP  - 38
PB  - Kernforschungsanlage
CY  - Jülich
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Lieder, R. M.
A1  - Didelez, J. P.
A1  - Beuscher, H.
T1  - Observation of a New Isomer in ²¹² Po
JF  - Physical review letters
Y1  - 1978
U6  - https://doi.org/10.1103/PhysRevLett.41.742
SN  - 0031-9007
VL  - 41
IS  - 11
SP  - 742
EP  - 745
PB  - American Physical Society
CY  - Ridge, NY
ER  - 
TY  - JOUR
A1  - Rateike, Franz-Matthias
A1  - Weyer, K. G.
A1  - Wiedenmann, H.
A1  - MacGillivray, W. R.
T1  - Observation of absorptive optical bistability in a fabry-perot cavity containing multiple atomic beams /  K. G. Weyer ;  H. Wiedenmann ;  M.  Rateike ; W. R. Mac Gillivray ; P. Meystre ; H. Walther
JF  - Optics communications. 37 (1981), H. 6
Y1  - 1981
SN  - 0030-4018
SP  - 426
EP  - 430
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Neskakis, A.
A1  - Lieder, R. M.
T1  - Observation of rotation-aligned bands in the odd-odd nuclei ¹⁹⁰,¹⁹²,¹⁹⁴ Au
JF  - Physics letters / B. 80 (1979), H. 3
Y1  - 1979
SN  - 0031-9163
N1  - 2. ISSN: 0370-2693
SP  - 194
EP  - 197
ER  - 
TY  - JOUR
A1  - Förster, Arnold
A1  - Schmidt, T.
A1  - Haug, R. J.
T1  - Observation of the local structure of landau bands in a disordered conductor / T. Schmidt ; R. J. Haug ; Vladimir I. Fal'ko ... A. Förster ...
JF  - Physical review letters. 78 (1997), H. 8
Y1  - 1997
SN  - 0031-9007
N1  - ISSN der E-Ausg.: 1079-7114
SP  - 1540
EP  - 1543
ER  - 
TY  - JOUR
A1  - Samm, Doris
A1  - Faissner, H.
A1  - Frenzel, E.
A1  - Heinrigs, W.
T1  - Observation of the two-photon decay of a light penetrating particle / H. Faissner, E. Frenzel, W. Heinrigs, A. Preussger, D. Samm und U. Samm
JF  - Physics Letters B. Vol. 103 (1980), H. Issues 3
Y1  - 1980
SP  - 234
EP  - 240
ER  - 
TY  - JOUR
A1  - Blome, Hans-Joachim
A1  - Wilson, Thomas L.
T1  - Observational cosmology from the moon. Wilson, Thomas, L.; Blome, Hans-Joachim
JF  - Engineering, construction, and operations in space V : proceedings of the Fifth International Conference on Space '96, Albuquerque, New Mexico, June 1-6, 1996 / sponsored by Aerospace Division of the American Society of Civil Engineers ... [et al.]; edite
Y1  - 1996
SN  - 0-7844-0177-2
SP  - 864
EP  - 870
PB  - The Society
CY  - New York
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Neskakis, A.
A1  - Beuscher, H.
A1  - Davidson, W. F.
T1  - Observations of backbending effects in ¹⁸¹,¹⁸²,¹⁸³,¹⁸⁴ Os nuclei
JF  - Annual report 1974 / Institut für Kernphysik Kernforschungsanlage Jülich
Y1  - 1975
SP  - 82
PB  - Verlag des Forschungszentrums Jülich
CY  - Jülich
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Neskakis, A.
A1  - Beuscher, H.
A1  - Gono, Y.
T1  - Observations of rotation-aligned bands in the odd-odd nuclei ¹⁹⁰,¹⁹²,¹⁹⁴ Au
JF  - Annual report 1978 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: A. Fässler. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 36)
Y1  - 1979
SP  - 34
PB  - Kernforschungsanlage
CY  - Jülich
ER  - 
TY  - JOUR
A1  - Bitz, Andreas
A1  - Zhou, Yi
A1  - El Quardi, Abdessamad
A1  - Streckert, Joachim
T1  - Occupational Exposure at Mobile Communication Base Station Antenna Sites
JF  - Frequenz
Y1  - 2009
U6  - https://doi.org/10.1515/FREQ.2009.63.7-8.123
SN  - 2191-6349
VL  - 63
IS  - 7-8
SP  - 123
EP  - 128
ER  - 
TY  - JOUR
A1  - Rossi, Leonardo
A1  - Holtschoppen, Britta
A1  - Butenweg, Christoph
T1  - Official data on the economic consequences of the 2012 Emilia-Romagna earthquake: a first analysis of database SFINGE
JF  - Bulletin of Earthquake Engineering
Y1  - 2019
U6  - https://doi.org/10.1007%2Fs10518-019-00655-8
VL  - 17
IS  - 9
SP  - 4855
EP  - 4884
PB  - Springer
CY  - Berlin
ER  -