TY - CHAP A1 - Seiler, Friedrich A1 - Pichler, Alexander A1 - Pfaff, Raphael A1 - George, Alfred A1 - Srulijes, Julio T1 - Improved Doppler picture velocimetry and new automated processing T2 - 14th International Symposium on Applications of Laser Techniques to Fluid Mechanics : Lisbon, Portugal, 7 - 10 July 2008 Y1 - 2008 SP - 1 EP - 12 ER - TY - CHAP A1 - Schwager, Christian A1 - Teixeira Boura, Cristiano José A1 - Flesch, Robert A1 - Alexopoulos, Spiros A1 - Herrmann, Ulf T1 - Improved efficiency prediction of a molten salt receiver based on dynamic cloud passage simulation T2 - AIP Conference Proceedings Y1 - 2019 SN - 978-0-7354-1866-0 U6 - https://doi.org/10.1063/1.5117566 VL - 2126 IS - 1 SP - 030054-1 EP - 030054-8 ER - TY - JOUR A1 - Götten, Falk A1 - Havermann, Marc A1 - Braun, Carsten A1 - Marino, Matthew A1 - Bil, Cees T1 - Improved Form Factor for Drag Estimation of Fuselages with Various Cross Sections JF - Journal of Aircraft N2 - The paper presents an aerodynamic investigation of 70 different streamlined bodies with fineness ratios ranging from 2 to 10. The bodies are chosen to idealize both unmanned and small manned aircraft fuselages and feature cross-sectional shapes that vary from circular to quadratic. The study focuses on friction and pressure drag in dependency of the individual body’s fineness ratio and cross section. The drag forces are normalized with the respective body’s wetted area to comply with an empirical drag estimation procedure. Although the friction drag coefficient then stays rather constant for all bodies, their pressure drag coefficients decrease with an increase in fineness ratio. Referring the pressure drag coefficient to the bodies’ cross-sectional areas shows a distinct pressure drag minimum at a fineness ratio of about three. The pressure drag of bodies with a quadratic cross section is generally higher than for bodies of revolution. The results are used to derive an improved form factor that can be employed in a classic empirical drag estimation method. The improved formulation takes both the fineness ratio and cross-sectional shape into account. It shows superior accuracy in estimating streamlined body drag when compared with experimental data and other form factor formulations of the literature. Y1 - 2020 U6 - https://doi.org/10.2514/1.C036032 SN - 1533-3868 SP - 1 EP - 13 PB - AIAA CY - Reston, Va. ER - TY - JOUR A1 - Lettini, Antonio A1 - Havermann, Marc A1 - Guidetti, Marco A1 - Fornaciari, Andrea T1 - Improved functionalities and energy saving potential on mobile machines combining electronics with flow sharing valve and variable displacement pump JF - IFK 7, 7th International Fluid Power Conference, Efficiency through Fluid Power, 7. Internationales Fluidtechnisches Kolloquium, Workshop Proceedings, Vol. 3, Aachen, DE, 22.-24. Mar, 2010 Y1 - 2010 SN - 978-3-940565-92-1 N1 - IFK, 7, Internationales Fluidtechnisches Kolloquium, 7., Aachen, DE, 2010-03-22 - 2010-03-24 SP - 103 EP - 114 PB - - ER - TY - JOUR A1 - Biselli, Manfred A1 - Noll, Thomas A1 - Eisenkrätzer, Detlef A1 - Kiesewetter, André T1 - Improved product formation in high density Chinese hamster ovary cell cultures transfected at confluency / Thomas Noll, Detlef Eisenkrätzer, André Kiesewetter, André Dinter, Steffen Zeng, Christian Wandrey, Manfred Biselli und Eric G. Berger JF - Biotechnology Letters. 24 (2002), H. 11 Y1 - 2002 SN - 0141-5492 SP - 861 EP - 866 ER - TY - JOUR A1 - Lowis, Carsten A1 - Ferguson, Simon A1 - Paulßen, Elisabeth A1 - Hoehr, Cornelia T1 - Improved Sc-44 production in a siphon-style liquid target on a medical cyclotron JF - Applied Radiation and Isotopes Y1 - 2021 U6 - https://doi.org/10.1016/j.apradiso.2021.109675 SN - 0969-8043 VL - 172 IS - Art. 109675 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Miyamoto, Koichiro A1 - Seki, Kosuke A1 - Suto, Takeyuki A1 - Werner, Frederik A1 - Wagner, Torsten A1 - Schöning, Michael Josef A1 - Yoshinobu, Tatsuo T1 - Improved spatial resolution of the chemical imaging sensor with a hybrid illumination that suppresses lateral diffusion of photocarriers JF - Sensor and Actuators B: Chemical N2 - The chemical imaging sensor is a semiconductor-based chemical sensor capable of visualizing pH and ion distributions. The spatial resolution depends on the lateral diffusion of photocarriers generated by illumination of the semiconductor substrate. In this study, two types of optical setups, one based on a bundle of optical fibers and the other based on a binocular tube head, were developed to project a hybrid illumination of a modulated light beam and a ring-shaped constant illumination onto the sensor plate. An improved spatial resolution was realized by the ring-shaped constant illumination, which suppressed lateral diffusion of photocarriers by enhanced recombination due to the increased carrier concentration. Y1 - 2018 U6 - https://doi.org/10.1016/j.snb.2018.07.016 SN - 0925-4005 VL - 273 SP - 1328 EP - 1333 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Grießmeier, M. A1 - Sonnenberg, F. A1 - Weckesser, M. A1 - Ziemons, Karl A1 - Langen, K.-J. A1 - Müller-Gärtner, H. W. T1 - Improvement of SPECT quantification in small brain structures by using experiment based recovery-coefficient corrections JF - European Journal of Nuclear Medicine Y1 - 1996 SN - 1619-7089 N1 - Abstracts ; PSu827 VL - 23 IS - 9 SP - 1238 EP - 1238 ER - TY - CHAP A1 - Dilthey, Ulrich A1 - Mund, F. A1 - Raupach, Michael A1 - Schleser, Markus A1 - Walk-Lauffer, Bernd T1 - Improvement of textile reinforced concrete by polymer additives T2 - ICPIC '04 : 11th International Congress on Polymers in Concrete : 2nd-4th June, 2004 at BAM, Berlin, Germany : proceedings / ed. by M. Maultzsch Y1 - 2004 SN - 3-00-013706-8 SP - 469 EP - 476 PB - BAM CY - Berlin ER - TY - CHAP A1 - Schleser, Markus A1 - Dilthey, Ulrich A1 - Mund, F. A1 - Böhm, Stefan ED - Czarnecki, Lech ED - Garbacz, Andrzej T1 - Improvement of textile reinforced concrete by use of polymers T2 - Adhesion in interfaces of building materials: a multi-scale approach : [Symposium "Adhesion in Building Bonds: Macro-, Micro- and Nano-Scale" at Warsaw University of Technology in the framework of the European Materials Research Society, fall meeting 2005 ; selected papers]. (Advances in materials science and restoration. No. 2) Y1 - 2007 SN - 978-3-931681-89-0 SP - 153 EP - 162 PB - Aedificatio Publ. CY - Freiburg ER - TY - CHAP A1 - Döring, Bernd A1 - Sedlacek, Gerhard T1 - Improvement of thermal comfort in light weight buildings made of steel with new concepts for slab systems T2 - 10th Nordic Steel Construction Conference, Copenhagen, Denmark 7-9. June 2004: NSCC 2004 : proceedings Y1 - 2004 SP - 35 EP - 44 PB - Danish Steel Inst. CY - Copenhagen ER - TY - JOUR A1 - Haj Ayed, A. A1 - Kusterer, K. A1 - Funke, Harald A1 - Keinz, Jan A1 - Striegan, Constantin A1 - Bohn, D. T1 - Improvement study for the dry-low-NOx hydrogen micromix combustion technology JF - Propulsion and power research Y1 - 2015 U6 - https://doi.org/10.1016/j.jppr.2015.07.003 SN - 2212-540X VL - Vol. 4 IS - Iss. 3 SP - 132 EP - 140 ER - TY - CHAP A1 - Niemueller, Tim A1 - Neumann, Tobias A1 - Henke, Christoph A1 - Schönitz, Sebastian A1 - Reuter, Sebastian A1 - Ferrein, Alexander A1 - Jeschke, Sabina A1 - Lakemeyer, Gerhard T1 - Improvements for a robust production in the RoboCup logistics league 2016 T2 - RoboCup 2016: Robot World Cup XX. RoboCup 2016. Y1 - 2017 SN - 978-3-319-68792-6 U6 - https://doi.org/10.1007/978-3-319-68792-6_49 SP - 589 EP - 600 PB - Springer CY - Cham ER - TY - JOUR A1 - Heuermann, Holger A1 - Ibrahim, Irfan T1 - Improvements in the flicker noise reduction technique for osillator designs / Ibrahim, Irfan ; Heuermann, Holger JF - European Microwave Conference, 2009 : EuMC 2009 ; Sept. 29, 2009 - Oct. 1, 2009, Rome, Italy ; part of European Microwave Week (EuMW) / sponsored by EuMA, European Microwave Association ... Endorsed by IEEE Y1 - 2009 SN - 978-1-4244-4748-0 N1 - EuMC 2009 SP - 1215 EP - 1218 PB - IEEE CY - Piscataway, NJ ER - TY - CHAP A1 - Alhwarin, Faraj A1 - Ferrein, Alexander A1 - Gebhardt, Andreas A1 - Kallweit, Stephan A1 - Scholl, Ingrid A1 - Tedjasukmana, Osmond Sanjaya T1 - Improving additive manufacturing by image processing and robotic milling T2 - 2015 IEEE International Conference on Automation Science and Engineering (CASE), Aug 24-28, 2015 Gothenburg, Sweden Y1 - 2015 U6 - https://doi.org/10.1109/CoASE.2015.7294217 SP - 924 EP - 929 ER - TY - CHAP A1 - Meck, Marvin M. A1 - Müller, Tim M. A1 - Altherr, Lena A1 - Pelz, Peter F. T1 - Improving an industrial cooling system using MINLP, considering capital and operating costs T2 - Operations Research Proceedings 2019 N2 - The chemical industry is one of the most important industrial sectors in Germany in terms of manufacturing revenue. While thermodynamic boundary conditions often restrict the scope for reducing the energy consumption of core processes, secondary processes such as cooling offer scope for energy optimisation. In this contribution, we therefore model and optimise an existing cooling system. The technical boundary conditions of the model are provided by the operators, the German chemical company BASF SE. In order to systematically evaluate different degrees of freedom in topology and operation, we formulate and solve a Mixed-Integer Nonlinear Program (MINLP), and compare our optimisation results with the existing system. KW - Engineering optimisation KW - Mixed-integer programming KW - Industrial optimisation KW - Cooling system KW - Process engineering Y1 - 2020 SN - 978-3-030-48438-5 (Print) SN - 978-3-030-48439-2 (Online) U6 - https://doi.org/10.1007/978-3-030-48439-2_61 N1 - Annual International Conference of the German Operations Research Society (GOR), Dresden, Germany, September 4-6, 2019. SP - 505 EP - 512 PB - Springer CY - Cham ER - TY - JOUR A1 - Thoma, Andreas A1 - Gardi, Alessandro A1 - Fisher, Alex A1 - Braun, Carsten T1 - Improving local path planning for UAV flight in challenging environments by refining cost function weights JF - CEAS Aeronautical Journal N2 - Unmanned Aerial Vehicles (UAV) constantly gain in versatility. However, more reliable path planning algorithms are required until full autonomous UAV operation is possible. This work investigates the algorithm 3DVFH* and analyses its dependency on its cost function weights in 2400 environments. The analysis shows that the 3DVFH* can find a suitable path in every environment. However, a particular type of environment requires a specific choice of cost function weights. For minimal failure, probability interdependencies between the weights of the cost function have to be considered. This dependency reduces the number of control parameters and simplifies the usage of the 3DVFH*. Weights for costs associated with vertical evasion (pitch cost) and vicinity to obstacles (obstacle cost) have the highest influence on the failure probability of the local path planner. Environments with mainly very tall buildings (like large American city centres) require a preference for horizontal avoidance manoeuvres (achieved with high pitch cost weights). In contrast, environments with medium-to-low buildings (like European city centres) benefit from vertical avoidance manoeuvres (achieved with low pitch cost weights). The cost of the vicinity to obstacles also plays an essential role and must be chosen adequately for the environment. Choosing these two weights ideal is sufficient to reduce the failure probability below 10%. KW - Bio-inspired systems KW - Path planning KW - Obstacle avoidance KW - Unmanned aerial vehicles Y1 - 2024 U6 - https://doi.org/10.1007/s13272-024-00741-x SN - 1869-5590 (eISSN) SN - 1869-5582 N1 - Corresponding author: Andreas Thoma PB - Springer CY - Wien ER - TY - BOOK A1 - Drumm, Christian T1 - Improving Schema Mapping by Exploiting Domain Knowledge Y1 - 2008 N1 - Karlsruhe, Univ., Diss., 2008 ER - TY - JOUR A1 - Schroth, P. A1 - Schöning, Michael Josef A1 - Schütz, S. A1 - Epanya, P. A1 - Steffen, A. A1 - Weißbecker, B. A1 - Hummel, Hans E. A1 - Kordos, P. A1 - Lüth, H. T1 - Improving the bioelectronic interface of an antenna/chip biosensor – technological aspects JF - Proceedings : The Hague, The Netherlands, September 12 - 15, 1999 / [ed. by M. Bartek]. Vol 1. Y1 - 1999 SN - 90-76699-02-X N1 - Eurosensors ; (13, 1999, 's-Gravenhage) ; Eurosensors ; (13 : ; 1999.09.12-15 : ; The Hague) ; European Conference on Solid-State Transducers ; (13 : ; 1999.09.12-15 : ; The Hague) SP - 569 EP - 572 CY - The Hague, The Netherlands ER - TY - JOUR A1 - Thust, M. A1 - Schroth, P. A1 - Töpler, A. A1 - Schöning, Michael Josef A1 - Müller-Veggian, Mattea A1 - Kordos, P. A1 - Lüth, H. T1 - Improving the detection limit of a capacitive sensor by means of a diffusion barrier JF - Eurosensors XII : proceedings of the 12th European Conference on Solid-State Transducers and the 9th UK Conference on Sensors and their Applications, Southampton, UK, 13 - 16 September 1998 / ed. by N. M. White ; Vol. 1 Y1 - 1998 SN - 0-7503-0595-9 N1 - Eurosensors ; (12, 1998, Southampton) ; UK Conference on Sensors and Their Applications ; (9, 1998, Southampton) SP - 507 EP - 510 PB - Inst. of Physics Publ. CY - Bristol [u.a.] ER - TY - JOUR A1 - Cosma, Cosmin A1 - Kessler, Julia A1 - Gebhardt, Andreas A1 - Campbell, Ian A1 - Balc, Nicolae T1 - Improving the Mechanical Strength of Dental Applications and Lattice Structures SLM Processed JF - Materials N2 - To manufacture custom medical parts or scaffolds with reduced defects and high mechanical characteristics, new research on optimizing the selective laser melting (SLM) parameters are needed. In this work, a biocompatible powder, 316L stainless steel, is characterized to understand the particle size, distribution, shape and flowability. Examination revealed that the 316L particles are smooth, nearly spherical, their mean diameter is 39.09 μm and just 10% of them hold a diameter less than 21.18 μm. SLM parameters under consideration include laser power up to 200 W, 250–1500 mm/s scanning speed, 80 μm hatch spacing, 35 μm layer thickness and a preheated platform. The effect of these on processability is evaluated. More than 100 samples are SLM-manufactured with different process parameters. The tensile results show that is possible to raise the ultimate tensile strength up to 840 MPa, adapting the SLM parameters for a stable processability, avoiding the technological defects caused by residual stress. Correlating with other recent studies on SLM technology, the tensile strength is 20% improved. To validate the SLM parameters and conditions established, complex bioengineering applications such as dental bridges and macro-porous grafts are SLM-processed, demonstrating the potential to manufacture medical products with increased mechanical resistance made of 316L. Y1 - 2020 U6 - https://doi.org/10.3390/ma13040905 SN - 1996-1944 VL - 13 IS - 4 SP - 1 EP - 18 PB - MDPI CY - Basel ER - TY - CHAP A1 - Thoma, Andreas A1 - Fisher, Alex A1 - Braun, Carsten T1 - Improving the px4 avoid algorithm by bio-inspired flight strategies T2 - DLRK2020 - „Luft- und Raumfahrt – Verantwortung in allen Dimensionen“ Y1 - 2020 U6 - https://doi.org/10.25967/530183 N1 - Deutscher Luft- und Raumfahrtkongress 2020, 1. bis 3. September 2020 – Online, „Luft- und Raumfahrt – Verantwortung in allen Dimensionen“ ER - TY - JOUR A1 - Noureddine, Yacine A1 - Kraff, Oliver A1 - Ladd, Mark E. A1 - Wrede, Karsten H. A1 - Chen, Bixia A1 - Quick, Harald H. A1 - Schaefers, Gregor A1 - Bitz, Andreas T1 - In vitro and in silico assessment of RF-induced heating around intracranial aneurysm clips at 7 Tesla JF - Magnetic Resonance in Medicine Y1 - 2017 U6 - https://doi.org/10.1002/mrm.26650 SN - 1522-2594 IS - Early view PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Temiz Artmann, Aysegül A1 - Resmi, Halil A1 - Akhunlar, Hülya A1 - Güner, Gül T1 - In vitro effects of high glucose concentrations on membrane protein sulfhydryl oxidation, G-actin and deformability of human erythrocytes. Resmi, Halil ; Akhunlar, Hülya ; Temiz Artmann, Aysegül ; Güner, Gül JF - Cell biochemistry and function. 23 (2005), H. 3 Y1 - 2005 SN - 0263-6484 SP - 163 EP - 168 ER - TY - JOUR A1 - Temiz Artmann, Aysegül A1 - Başkurt, Oǧuz Kerim A1 - Edremitlioglu, M. T1 - In vitro effects of in vivo activated leukocytes on red blood cell filterability and lipid peroxidation. Baskurt, O.K.; Edremitlioglu, M.; Temiz, A. JF - Clinical Hemorheology. 14 (1994), H. 4 Y1 - 1994 SP - 591 EP - 596 ER - TY - JOUR A1 - Bleilevens, Christian A1 - Hill, Aileen A1 - Grzanna, Tim A1 - Fechter, Tamara A1 - Bohnen, Melanie A1 - Weber, Hans-Joachim A1 - Beckers, Christian A1 - Borosch, Sebastian A1 - Zayat, Rashad A1 - Benstoem, Carin A1 - Rossaint, Rolf A1 - Goetzenich, Andreas T1 - In vitro head-to-head comparison of anticoagulation properties of two heparin brands in a human blood miniature mock loop JF - Interactive cardiovascular and thoracic surgery Y1 - 2019 U6 - https://doi.org/10.1093/icvts/ivy206 SN - 1569-9285 VL - 28 IS - 1 SP - 120 EP - 127 ER - TY - JOUR A1 - Brockhaus, Moritz K. A1 - Behbahani, Mehdi A1 - Muris, Farina A1 - Jansen, Sebastian V. A1 - Schmitz-Rode, Thomas A1 - Steinseifer, Ulrich A1 - Clauser, Johanna C. T1 - In vitro thrombogenicity testing of pulsatile mechanical circulatory support systems: Design and proof-of-concept JF - Artificial Organs N2 - Thrombogenic complications are a main issue in mechanical circulatory support (MCS). There is no validated in vitro method available to quantitatively assess the thrombogenic performance of pulsatile MCS devices under realistic hemodynamic conditions. The aim of this study is to propose a method to evaluate the thrombogenic potential of new designs without the use of complex in-vivo trials. This study presents a novel in vitro method for reproducible thrombogenicity testing of pulsatile MCS systems using low molecular weight heparinized porcine blood. Blood parameters are continuously measured with full blood thromboelastometry (ROTEM; EXTEM, FIBTEM and a custom-made analysis HEPNATEM). Thrombus formation is optically observed after four hours of testing. The results of three experiments are presented each with two parallel loops. The area of thrombus formation inside the MCS device was reproducible. The implantation of a filter inside the loop catches embolizing thrombi without a measurable increase of platelet activation, allowing conclusions of the place of origin of thrombi inside the device. EXTEM and FIBTEM parameters such as clotting velocity (α) and maximum clot firmness (MCF) show a total decrease by around 6% with a characteristic kink after 180 minutes. HEPNATEM α and MCF rise within the first 180 minutes indicate a continuously increasing activation level of coagulation. After 180 minutes, the consumption of clotting factors prevails, resulting in a decrease of α and MCF. With the designed mock loop and the presented protocol we are able to identify thrombogenic hot spots inside a pulsatile pump and characterize their thrombogenic potential. Y1 - 2021 U6 - https://doi.org/10.1111/aor.14046 SN - 1525-1594 VL - 45 IS - 12 SP - 1513 EP - 1521 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Kobus, Thiele A1 - Bitz, Andreas A1 - Uden, Mark J. van A1 - Lagemaat, Miram W. A1 - Rothgang, Eva A1 - Orzada, Stephan A1 - Heerschap, Arend A1 - Scheenen, Tom W. J. T1 - In vivo 31P MR spectroscopic imaging of the human prostate at 7 T: safety and feasibility JF - Magnetic Resonance in Medicine N2 - 31P MR spectroscopic imaging of the human prostate provides information about phosphorylated metabolites that could be used for prostate cancer characterization. The sensitivity of a magnetic field strength of 7 T might enable 3D 31P MR spectroscopic imaging with relevant spatial resolution in a clinically acceptable measurement time. To this end, a 31P endorectal coil was developed and combined with an eight-channel 1H body-array coil to relate metabolic information to anatomical location. An extensive safety validation was performed to evaluate the specific absorption rate, the radiofrequency field distribution, and the temperature distribution of both coils. This validation consisted of detailed Finite Integration Technique simulations, confirmed by MR thermometry and Burn:x-wiley:07403194:media:MRM24175:tex2gif-stack-1 measurements in a phantom and in vivo temperature measurements. The safety studies demonstrated that the presence of the 31P endorectal coil had no influence on the specific absorption rate levels and temperature distribution of the external eight-channel 1H array coil. To stay within a 10 g averaged local specific absorption rate of 10 W/kg, a maximum time-averaged input power of 33 W for the 1H array coil was allowed. For transmitting with the 31P endorectal coil, our safety limit of less than 1°C temperature increase in vivo during a 15-min MR spectroscopic imaging experiment was reached at a time-averaged input power of 1.9 W. With this power setting, a second in vivo measurement was performed on a healthy volunteer. Using adiabatic excitation, 3D 31P MR spectroscopic imaging produced spectra from the entire prostate in 18 min with a spatial resolution of 4 cm3. The spectral resolution enabled the separate detection of phosphocholine, phosphoethanolamine, inorganic phosphate, and other metabolites that could play an important role in the characterization of prostate cancer. Y1 - 2012 U6 - https://doi.org/10.1002/mrm.24175 SN - 1522-2594 VL - 68 IS - 6 SP - 1683 EP - 1695 PB - Wiley-Liss CY - New York ER - TY - CHAP A1 - Weber, Hans-Joachim A1 - Porschen, W. A1 - Dietzel, F. ED - Streffer, Christian T1 - In vivo analysis of the influence of combined hyperthermia and gamma irradiation on euoxic and hypoxic tumor cells T2 - Cancer therapy by hyperthermia and radiation : [proceedings of the 2. International Symposium on Cancer Therapy by Hyperthermia and Radiation, Essen, 2.-4.6.1977] Y1 - 1978 SN - 0-8067-1701-7 SN - 3-541-71701-7 SP - 276 EP - 277 PB - Urban and Schwarzenberg CY - Baltimore ; Munich [u.a.] ER - TY - JOUR A1 - Porschen, W. A1 - Gartzen, J. A1 - Gewehr, K. A1 - Mühlensiepen, H. A1 - Weber, Hans-Joachim A1 - Feinedegen, L E. T1 - In vivo assay of the radiation sensitivity of hypoxic tumour cells : influence of γ-rays, cyclotron neutrons, misonidazole, hyperthermia and mixed modalities JF - The British journal of cancer / Supplement N2 - Tumour cell death can be evaluated in the living mouse by externally measuring the rate of loss of tumour-bound DNA tracer. By sequentially labelling the tumour-bearing animals with ¹²⁵IUdR and ¹³¹IUdR 50 h apart, the average tumour cells at the time of the second injection are labelled by ¹²⁵IUdR and the euoxic tumour cells are specifically labelled with ¹³¹IUdR. Tumour treatment at this stage of labelling permits the observation of the reaction of euoxic cells and average tumour cells and finally yields data on hypoxic cells and thus on the oxygen enhancement ratio. This information adds to results from tumour control and growth delay. With this technique effects were analysed of 60-Co γ-rays, cyclotron neutrons (E = 6 MeV), misonidazole (500 mg/kg body wt) and hyperthermia (42°C water-bath), or combinations of these. Misonidazole (15 min before irradiation) altered the oxygen enhancement ratio by a factor of 1·5 for γ-rays and of 1·1 for neutrons; when evaluated from tumour-growth delay and TCD-50 misonidazole gave a dose modifying factor of 1·47 for γ-rays and of 1·2-1·3 for neutrons. Based on percentage tumour regression 100 days after treatment, the enhancement ratio from hyperthermia (after irradiation) was 2·75 for γ-rays (at 10 Gray) and 2·2 for neutrons (at 3·2 Gray). For neutrons combined with misonidazole and hyperthermia the ratio was 2·4. These results demonstrate that effects of neutron irradiation may be modified by electron-affinic substances and/or hyperthermia. Y1 - 1978 SN - 0306-9443 N1 - Section 6: Sensitization and Hypoxic Cytotoxicity: Effects of Hyperthermia and High Let IS - 3 SP - 194 EP - 197 PB - Lewis CY - London ER - TY - CHAP A1 - Richter, Charlotte A1 - Braunstein, Bjoern A1 - Stäudle, Benjamin A1 - Attias, Julia A1 - Suess, Alexander A1 - Weber, T. A1 - Rittweger, Joern A1 - Green, David A. A1 - Albracht, Kirsten T1 - In vivo fascicle length of the gastrocnemius muscle during walking in simulated martian gravity using two different body weight support devices T2 - 23rd Annual Congress of the European College of Sport Science, Dublin, Irland Y1 - 2018 ER - TY - JOUR A1 - Scheer, Nico A1 - Ross, Jillian A1 - Kapelyukh, Yury A1 - Rode, Anja A1 - Wolf, C. Roland T1 - In vivo responses of the human and murine pregnane X receptor to dexamethasone in mice JF - Drug Metabolism and Disposition N2 - Dexamethasone (DEX) is a potent and widely used anti-inflammatory and immunosuppressant glucocorticoid. It can bind and activate the pregnane X receptor (PXR), which plays a critical role as xenobiotic sensor in mammals to induce the expression of many enzymes, including cytochromes P450 in the CYP3A family. This induction results in its own metabolism. We have used a series of transgenic mouse lines, including a novel, improved humanized PXR line, to compare the induction profile of PXR-regulated drug-metabolizing enzymes after DEX administration, as well as looking at hepatic responses to rifampicin (RIF). The new humanized PXR model has uncovered further intriguing differences between the human and mouse receptors in that RIF only induced Cyp2b10 in the new humanized model. DEX was found to be a much more potent inducer of Cyp3a proteins in wild-type mice than in mice humanized for PXR. To assess whether PXR is involved in the detoxification of DEX in the liver, we analyzed the consequences of high doses of the glucocorticoid on hepatotoxicity on different PXR genetic backgrounds. We also studied these effects in an additional mouse model in which functional mouse Cyp3a genes have been deleted. These strains exhibited different sensitivities to DEX, indicating a protective role of the PXR and CYP3A proteins against the hepatotoxicity of this compound. Y1 - 2010 U6 - https://doi.org/10.1124/dmd.109.031872 SN - 1521-009X VL - 38 IS - 7 SP - 1046 EP - 1053 PB - ASPET CY - Bethesda ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Haenni, D. R. A1 - Beuscher, H. A1 - Lieder, R. M. T1 - In-beam studies of ¹⁴⁵ Gd and ¹⁴⁵ Eu JF - Frühjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft (1979) Y1 - 1979 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Zuber, K. A1 - Gueven, H. T1 - In-beam study of 63 143 Eu 80 JF - Zeitschrift für Physik / A, Hadrons and nuclei. 330 (1988), H. 3 Y1 - 1988 SN - 1431-5831 N1 - 2. ISSN: 0340-2193 ; 3. ISSN 0930-1151 ; 4. ISSN 0939-7922 SP - 343 EP - 344 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Haenni, D. R. A1 - Beuscher, H. A1 - Lieder, R. M. T1 - In-beam study of levels in ¹⁴⁵ Eu JF - Structure of medium-heavy nuclei, 1979 : proceedings of the 6. European Physical Soc. Nuclear Divisional Conference on the Structure of Medium-Heavy Nuclei held in Rhodes, Greece, 1-4 May 1979 / ed. Committee: G. S. Anagnostatos ... - (Conference series / Institute of Physics London, Bristol ; 49) Y1 - 1980 SN - 0-85498-140-3 N1 - Conference on the Structure of Medium Heavy Nuclei <6, 1979, Rodos> ; European Physical Society / Nuclear Physics Division SP - 131 PB - Inst. of Physics CY - Bristol ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Beuscher, H. A1 - Haenni, D. R. T1 - In-beam study of the light transitional nucleus ¹³⁸ Nd JF - Annual report 1979 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: A. Fässler. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 72) Y1 - 1980 SP - 45 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Morek, T. A1 - Beuscher, H. A1 - Bochev, B. T1 - In-beam study of the odd-odd nuclei ¹³⁴ La and ¹³⁶ La JF - Nuclear physics / A, Nuclear and hadronic physics. 433 (1985), H. 2 Y1 - 1985 SN - 0375-9474 SP - 159 EP - 180 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Zuber, K. A1 - Gueven, H. T1 - In-beam study of ¹⁴³ Eu JF - Annual report 1987 / Kernforschungsanlage Jülich Institut für Kernphysik / Grümmer , F. (Hrsg.) . - (Spezielle Berichte der Kernforschungsanlage Jülich ; 442) Y1 - 1988 SP - 44 PB - Verlag des Forschungszentrums Jülich CY - Jülich ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Mariscotti, M. A. J. A1 - Beuscher, H. A1 - Davidson, W. F. T1 - In-beam study of ¹⁴⁴ Gd JF - Nuclear physics / A. 311 (1978), H. 3 Y1 - 1978 SN - 0375-9474 SP - 395 EP - 412 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Mariscotti, M. A. J. A1 - Beuscher, H. A1 - Davidson, W. F. T1 - In-beam study of ¹⁴⁴ Gd JF - Proceedings of the International Conference on Nuclear Structure : Tokyo, Sept. 5 - 10, 1977 / ed. by T. Marumori. - Journal of the Physical Society of Japan ; Vol. 44, 1978 : Suppl. Y1 - 1978 N1 - International Conference on Nuclear Structure <1977, Tokyo> SP - 863 PB - Physical Soc. of Japan CY - Tokyo ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Mariscotti, M. A. J. A1 - Beuscher, H. A1 - Davidson, W. F. T1 - In-beam study of ¹⁴⁴ Gd JF - Annual report 1976 / Institut für Kernphysik Kernforschungsanlage Jülich / Ed. board: A. Fäßler ... Y1 - 1977 SP - 37 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Haenni, D. R. A1 - Beuscher, H. A1 - Lieder, R. M. T1 - In-beam study of ¹⁴⁵ Gd JF - Annual report 1978 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: A. Fässler. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 36) Y1 - 1979 SP - 27 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Gono, Y. A1 - Lieder, R. M. T1 - In-beam γ-ray study of ¹⁸⁹,¹⁹¹,¹⁹³ Au JF - Nuclear physics / A. 327 (1979), H. 2 Y1 - 1979 SN - 0375-9474 SP - 269 EP - 287 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Kreiner, A. J. A1 - Fenzl, M. A1 - Kutschera, W. T1 - In-beam γ-spectroscopic investigation of ¹⁹⁶ Tl JF - Annual report 1977 / Institut für Kernphysik Kernforschungsanlage Jülich Y1 - 1978 N1 - Spezielle Berichte der Kernforschungsanlage Jülich ; 15 SP - 47 EP - 48 PB - Verlag des Forschungszentrums Jülich CY - Jülich ER - TY - CHAP A1 - Neu, Eugen A1 - Janser, Frank A1 - Khatibi, Akbar A. A1 - Orifici, Adrian C. T1 - In-flight vibration-based structural health monitoring of aircraft wings T2 - 30th Congress of the internatonal council of the aeronautical sciences : 25.-30. September 2016, Daejeon, Korea N2 - This work presents a methodology for automated damage-sensitive feature extraction and anomaly detection under multivariate operational variability for in-flight assessment of wings. The method uses a passive excitation approach, i. e. without the need for artificial actuation. The modal system properties (natural frequencies and damping ratios) are used as damage-sensitive features. Special emphasis is placed on the use of Fiber Bragg Grating (FBG) sensing technology and the consideration of Operational and Environmental Variability (OEV). Measurements from a wind tunnel investigation with a composite cantilever equipped with FBG and piezoelectric sensors are used to successfully detect an impact damage. In addition, the feasibility of damage localisation and severity estimation is evaluated based on the coupling found between damageand OEV-induced feature changes. Y1 - 2016 ER - TY - JOUR A1 - Teumer, T. A1 - Capitain, C. A1 - Ross-Jones, J. A1 - Tippkötter, Nils A1 - Rädle, M. A1 - Methner, F.-J. T1 - In-line Haze Monitoring Using a Spectrally Resolved Back Scattering Sensor JF - BrewingScience N2 - In the present work an optical sensor in combination with a spectrally resolved detection device for in-line particle-size-monitoring for quality control in beer production is presented. The principle relies on the size and wavelength dependent backscatter of growing particles in fluids. Measured interference structures of backscattered light are compared with calculated theoretical values, based on Mie-Theory, and fitted with a linear least square method to obtain particle size distributions. For this purpose, a broadband light source in combination with a process-CCD-spectrometer (charge ? coupled device spectrometer) and process adapted fiber optics are used. The goal is the development of an easy and flexible measurement device for in-line-monitoring of particle size. The presented device can be directly installed in product fill tubes or vessels, follows CIP- (cleaning in place) and removes the need of sample taking. A proof of concept and preliminary results, measuring protein precipitation, are presented. Y1 - 2018 SN - 1613-2041 VL - 71 IS - 5/6 SP - 49 EP - 55 PB - Fachverlag Hans Carl CY - Nürnberg ER - TY - JOUR A1 - Mistler, Michael A1 - Anthoine, A. A1 - Butenweg, Christoph T1 - In-plane and out-of-plane homogenisation of masonry JF - Computers & structures Y1 - 2007 U6 - https://doi.org/10.1016/j.compstruc.2006.08.087 SN - 1879-2243 (E-Journal); 0045-7949 (Print) VL - Volume 85 IS - Issues 17-18 SP - 1321 EP - 1330 ER - TY - GEN A1 - Digel, Ilya T1 - In-situ biological decontamination of an ice melting probe Y1 - 2010 N1 - 38th COSPAR Scientific Assembly. Held 18-15 July 2010, in Bremen, Germany Abstract unter https://www.cospar-assembly.org/abstractcd/OLD/COSPAR-10/abstracts/data/pdf/abstracts/F36-0013-10.pdf ER - TY - CHAP A1 - Digel, Ilya A1 - Leimena, W. A1 - Dachwald, Bernd A1 - Linder, Peter A1 - Porst, Dariusz A1 - Kayser, Peter A1 - Funke, O. A1 - Temiz Artmann, Aysegül A1 - Artmann, Gerhard T1 - In-situ biological decontamination of an ice melting probe : [abstract] N2 - The objective of our study was to investigate the efficacy of different in-situ decontamination protocols in the conditions of thermo-mechanical ice-melting. KW - Sonde KW - Dekontamination KW - Wasserstoffperoxid KW - Natriumhypochlorit Y1 - 2010 ER - TY - JOUR A1 - Prume, Klaus A1 - Reichenberg, B. A1 - Roelofs, A. A1 - Waser, R. T1 - In-situ compensation of the parasitic capacitance for nanoscale hysteresis measurements / Schmitz, T. ; Prume, K. ; Reichenberg, B. ; Roelofs, A. ; Waser, R. ; Tiedke, S. JF - Journal of the European Ceramic Society. 24 (2004), H. 6 Y1 - 2004 SN - 0955-2219 N1 - Electroceramics VIII SP - 1145 EP - 1147 ER -