TY - JOUR A1 - Paulßen, Elisabeth A1 - Hoehr, Cornelia A1 - Hou, Xinchi A1 - Hanemaayer, Victoire A1 - Zeisler, Stefan A1 - Adam, Michael J. A1 - Ruth, Thomas J. A1 - Celler, Anna A1 - Buckley, Ken A1 - Benard, Francois A1 - Schaffer, Paul T1 - Production of Y-86 and other radiometals for research purposes using a solution target system JF - Nuclear medicine and biology Y1 - 2015 U6 - http://dx.doi.org/10.1016/j.nucmedbio.2015.06.005 SN - 1872-9614 VL - 42 IS - 11 SP - 842 EP - 849 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Biselli, Manfred A1 - Born, C. A1 - Wandrey, C. T1 - Production of monoclonal antibodies in a pilot scale fluidized bed bioreactor / Born, C.; Biselli, M.; Wandrey, C. JF - Animal cell technology : developments towards the 21st century / edited by E. C. Beuvery Y1 - 1995 SN - 0-7923-3736-0 N1 - Meeting "Animal Cell Technology, Developments towards the 21st Century" ; <1994.09.12-16 : ; Veldhoven> SP - 515 EP - 519 PB - Kluwer Acad. Press CY - Dordrecht ER - TY - JOUR A1 - Khedim, Ahmed A1 - Schwarzer, Klemens A1 - Faber, Christian A1 - Müller, Christoph T1 - Production décentralisée de l'eau potable à l'énergie solaire JF - Desalination. 168 (2004), H. 1-3 Y1 - 2004 SN - 0011-9164 N1 - Sprache: Franz. SP - 13 EP - 20 ER - TY - JOUR A1 - Hillen, Walter T1 - Production and properties of the τ-lepton in e+e− annihilation at C.M. energies from 12 to 31.6 GeV. TASSO Collaboration JF - Physics Letters B. 92 (1980), H. 1-2 Y1 - 1980 SN - 0370-2693 SP - 199 EP - 205 ER - TY - JOUR A1 - Kopp, Alexander A1 - Schmeets, Ralf A1 - Gosau, Martin A1 - Friedrich, Reinhard E. A1 - Fuest, Sandra A1 - Behbahani, Mehdi A1 - Barbeck, Mike A1 - Rutkowski, Rico A1 - Burg, Simon A1 - Kluwe, Lan A1 - Henningsen, Anders T1 - Production and Characterization of Porous Fibroin Scaffolds for Regenerative Medical Application JF - In Vivo Y1 - 2019 U6 - http://dx.doi.org/10.21873/invivo.11536 SN - 1791-7549 VL - 33 IS - 3 SP - 757 EP - 762 ER - TY - JOUR A1 - Kluczka, Sven A1 - Eckstein, Julian A1 - Alexopoulos, Spiros A1 - Vaeßen, Christiane A1 - Roeb, Martin T1 - Process simulation for solar steam and dry reforming JF - Energy procedia : Proceedings of the SolarPACES 2013 International Conference N2 - In co-operation with the German Aerospace Center, the Solar-Institut Jülich has been analyzing the different technologies that are available for methanol production from CO2 using solar energy. The aim of the project is to extract CO2 from industrial exhaust gases or directly from the atmosphere to recycle it by use of solar energy. Part of the study was the modeling and simulating of a methane reformer for the production of synthesis gas, which can be operated by solar or hybrid heat sources. The reformer has been simplified in such a way that the model is accurate and enables fast calculations. The developed pseudo-homogeneous one- dimensional model can be regarded as a kind of counter-current heat exchanger and is able to incorporate a steam reforming reaction as well as a dry reforming reaction. Y1 - 2014 U6 - http://dx.doi.org/10.1016/j.egypro.2014.03.092 SN - 1876-6102 (E-Journal) VL - 49 SP - 850 EP - 859 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Fateri, Miranda A1 - Gebhardt, Andreas T1 - Process Parameters Development of Selective Laser Melting of Lunar Regolith for On-Site Manufacturing Applications JF - International Journal of Applied Ceramic Technology Y1 - 2015 SN - 1744-7402 U6 - http://dx.doi.org/10.1111/ijac.12326 VL - 12 IS - 1 SP - 46 EP - 52 PB - Wiley-Blackwell CY - Oxford ER - TY - JOUR A1 - Gerigk, M. A1 - Bujnicki, R. A1 - Ganpo-Nkwenkwa, E. A1 - Bongaerts, Johannes A1 - Sprenger, G. A1 - Takors, Ralf T1 - Process control for enhanced L-phenylalanine production using different recombinant Escherichia coli strains JF - Biotechnology and bioengineering Y1 - 2002 SN - 1097-0290 (E-Journal); 0006-3592 (Print) VL - Vol. 80 IS - Iss. 7 SP - 746 EP - 754 ER - TY - JOUR A1 - Schiffer, Stefan A1 - Ferrein, Alexander A1 - Lakemeyer, Gerhard T1 - Proceedings of the Fourth International Conference on Intelligent Robotics and Applications (ICIRA 2011) JF - Proceedings of the Fourth International Conference on Intelligent Robotics and Applications (ICIRA 2011) Y1 - 2010 SP - 1 EP - 10 ER - TY - JOUR A1 - Heuermann, Holger A1 - Schiek, B. T1 - Procedures for the Determination of the Scattering Parameters for Network Analyzer Calibration JF - IEEE transactions on instrumentation and measurement : IM / Institute of Electrical and Electronics Engineers, Instrumentation and Measurement Group. 42 (1993), H. 2 Y1 - 1993 SN - 0018-9456 SP - 528 EP - 531 ER - TY - JOUR A1 - Tüg, Helmut A1 - Baumann, Marcus T1 - Problems of UV-B radiation measurements in biological research : critical remarks on current techniques and suggestions for improvements JF - Geophysical research letters Y1 - 1994 SN - 1944-8007 (E-Journal); 0094-8276 (Print) VL - Vol. 21 IS - Iss. 8 SP - 689 EP - 692 ER - TY - JOUR A1 - Staat, Manfred T1 - Problems and Chances for Probabilistic Fracture Mechanics in the Analysis of Steel Pressure Boundary Reliability JF - Technical feasibility and reliability of passive safety systems for nuclear power plants. Proceedings of an Advisory Group Meeting held in Jülich, 21-24 November 1994 Y1 - 1996 N1 - IAEA-TECDOC-920 ; Onlinezugriff erfolgt auf die überarb. Ausg. 2006 SP - 43 EP - 55 CY - Vienna ER - TY - JOUR A1 - Engelmann, Ulrich M. A1 - Pourshahidi, Mohammad Ali A1 - Shalaby, Ahmed A1 - Krause, Hans-Joachim T1 - Probing particle size dependency of frequency mixing magnetic detection with dynamic relaxation simulation JF - Journal of Magnetism and Magnetic Materials N2 - Biomedical applications of magnetic nanoparticles (MNP) fundamentally rely on the particles’ magnetic relaxation as a response to an alternating magnetic field. The magnetic relaxation complexly depends on the interplay of MNP magnetic and physical properties with the applied field parameters. It is commonly accepted that particle core size is a major contributor to signal generation in all the above applications, however, most MNP samples comprise broad distribution spanning nm and more. Therefore, precise knowledge of the exact contribution of individual core sizes to signal generation is desired for optimal MNP design generally for each application. Specifically, we present a magnetic relaxation simulation-driven analysis of experimental frequency mixing magnetic detection (FMMD) for biosensing to quantify the contributions of individual core size fractions towards signal generation. Applying our method to two different experimental MNP systems, we found the most dominant contributions from approx. 20 nm sized particles in the two independent MNP systems. Additional comparison between freely suspended and immobilized MNP also reveals insight in the MNP microstructure, allowing to use FMMD for MNP characterization, as well as to further fine-tune its applicability in biosensing. Y1 - 2022 U6 - http://dx.doi.org/10.1016/j.jmmm.2022.169965 SN - 0304-8853 VL - 563 IS - In progress, Art. No. 169965 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kern, Alexander A1 - Schelthoff, Christof A1 - Mathieu, Moritz T1 - Probability of lightning strikes to air-terminations of structures using the electro-geometrical model theory and the statistics of lightning current parameters Y1 - 2010 N1 - 30th International Conference on Lightning Protection, Cagliari (Italien), 2010 SP - 750-1 EP - 750-8 ER - TY - JOUR A1 - Kern, Alexander A1 - Schelthoff, Christof A1 - Mathieu, Moritz T1 - Probability of lightning strikes to air-terminations of structures using the electro-geometrical model theory and the statistics of lightning current parameters JF - Atmospheric Research. 104 (2011) Y1 - 2011 SN - 0169-8095 N1 - Article in Press PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Staat, Manfred A1 - Heitzer, M. T1 - Probabilistic limit and shakedown problems JF - Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M; Heitzer, M. Y1 - 2003 SN - 3-00-010001-6 SP - 217 EP - 268 PB - John von Neumann Institute for Computing (NIC) CY - Jülich ER - TY - JOUR A1 - Tran, Thanh Ngoc A1 - Kreißig, R. A1 - Staat, Manfred T1 - Probabilistic limit and shakedown analysis of thin plates and shells JF - Structural safety. 31 (2009), H. 1 Y1 - 2009 SN - 0167-4730 SP - 1 EP - 18 PB - - ER - TY - JOUR A1 - Staat, Manfred T1 - Probabilistic assessment of the fracture mechanics behaviour of an HTR-module primary circuit pressure boundary JF - Nuclear Engineering and Design. 160 (1996), H. 1-2 Y1 - 1996 SN - 0029-5493 SP - 221 EP - 236 ER - TY - JOUR A1 - Thoma, Andreas A1 - Thomessen, Karolin A1 - Gardi, Alessandro A1 - Fisher, A. A1 - Braun, Carsten T1 - Prioritising paths: An improved cost function for local path planning for UAV in medical applications JF - The Aeronautical Journal N2 - Even the shortest flight through unknown, cluttered environments requires reliable local path planning algorithms to avoid unforeseen obstacles. The algorithm must evaluate alternative flight paths and identify the best path if an obstacle blocks its way. Commonly, weighted sums are used here. This work shows that weighted Chebyshev distances and factorial achievement scalarising functions are suitable alternatives to weighted sums if combined with the 3DVFH* local path planning algorithm. Both methods considerably reduce the failure probability of simulated flights in various environments. The standard 3DVFH* uses a weighted sum and has a failure probability of 50% in the test environments. A factorial achievement scalarising function, which minimises the worst combination of two out of four objective functions, reaches a failure probability of 26%; A weighted Chebyshev distance, which optimises the worst objective, has a failure probability of 30%. These results show promise for further enhancements and to support broader applicability. KW - Path planning KW - Cost function KW - Multi-objective optimization Y1 - 2023 U6 - http://dx.doi.org/10.1017/aer.2023.68 SN - 0001-9240 (Print) SN - 2059-6464 (Online) IS - First View SP - 1 EP - 18 PB - Cambridge University Press CY - Cambridge ER - TY - JOUR A1 - Matcha, Heike A1 - Ljubas, Ante A1 - Gueldemet, Harun ED - Kepczynska-Walczak, A. T1 - Printing a Coffee Bar: An investigation into mid-scale 3D printing JF - Computing for a better tomorrow - Proceedings of the 36th eCAADe Conference - Volume 2, Lodz University of Technology, Lodz, Poland, 19-21 September 2018 N2 - We present and discuss an exploration of the possibilities and properties of 3D printing with a printing space of 1 cubic meter, and how those can be integrated into architectural education through an experimental design and research course with students of architecture.We expand on issues presented at the eCAADe conference 2017 in Rome [Ref 6] by increasing the complexity and size of our prints, printing not a model to scale, but a full scale funtional prototype of a usable architectural object: A coffee bar. Y1 - 2018 SP - 59 EP - 68 ER - TY - JOUR A1 - Digel, Ilya T1 - Primary thermosensory events in cells JF - Transient receptor potential channels / Md. Shahidul Islam, ed. Y1 - 2011 SN - 978-94-007-0264-6 N1 - (Advances in experimental medicine and biology ; 704) SP - 451 EP - 468 PB - Springer CY - Dordrecht [u.a.] ER - TY - JOUR A1 - Rausch, Valentin A1 - Kahmann, Stephanie Lucina A1 - Baltschun, Christoph A1 - Staat, Manfred A1 - Müller, Lars P. A1 - Wegmann, Kilian T1 - Pressure distribution to the distal biceps tendon at the radial tuberosity: a biomechanical study JF - The Journal of Hand Surgery N2 - Purpose Mechanical impingement at the narrow radioulnar space of the tuberosity is believed to be an etiological factor in the injury of the distal biceps tendon. The aim of the study was to compare the pressure distribution at the proximal radioulnar space between 2 fixation techniques and the intact state. Methods Six right arms and 6 left arms from 5 female and 6 male frozen specimens were used for this study. A pressure transducer was introduced at the height of the radial tuberosity with the intact distal biceps tendon and after 2 fixation methods: the suture-anchor and the cortical button technique. The force (N), maximum pressure (kPa) applied to the radial tuberosity, and the contact area (mm²) of the radial tuberosity with the ulna were measured and differences from the intact tendon were detected from 60° supination to 60° pronation in 15° increments with the elbow in full extension and in 45° and 90° flexion of the elbow. Results With the distal biceps tendon intact, the pressures during pronation were similar regardless of extension and flexion and were the highest at 60° pronation with 90° elbow flexion (23.3 ± 53.5 kPa). After repair of the tendon, the mean peak pressure, contact area, and total force showed an increase regardless of the fixation technique. Highest peak pressures were found using the cortical button technique at 45° flexion of the elbow and 60° pronation. These differences were significantly different from the intact tendon. The contact area was significantly larger in full extension and 15°, 30°, and 60° pronation using the cortical button technique. Conclusions Pressures on the distal biceps tendon at the radial tuberosity increase during pronation, especially after repair of the tendon. Clinical relevance Mechanical impingement could play a role in both the etiology of primary distal biceps tendon ruptures and the complications occurring after fixation of the tendon using certain techniques. Y1 - 2020 U6 - http://dx.doi.org/10.1016/j.jhsa.2020.01.006 SN - 0363-5023 VL - 45 IS - 8 SP - 776.e1 EP - 776.e9 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Prielmeier, Franz A1 - Lang, E. W. A1 - Lüdemann, H.-D. T1 - Pressure dependence of the self-diffusion in liquid trifluoromethane / F. X. Prielmeier; E. W. Lang; H.-D. Lüdemann JF - Molecular Physics. 52 (1984), H. 5 Y1 - 1984 SN - 0026-8976 SP - 1105 EP - 1113 ER - TY - JOUR A1 - Prielmeier, Franz A1 - Woznyj, M. A1 - Lüdemann, H.-D. T1 - Pressure Dependence of the Melting and Self Diffusion in 2,2-Dimethylpropane, 2,2-Dimethylpropionitrile, and 2-Methylpropanol-2 / M. Woznyj, F. X. Prielmeier, H.-D. Lüdemann JF - Zeitschrift für Naturforschung A, Journal of Physical Sciences. 39 (1984) Y1 - 1984 SN - 0932-0784 SP - 800 ER - TY - JOUR A1 - Gossla, Ulrich A1 - Sato, R. T1 - Present production circumstances of aggregate in Germany / Sato, R.; Gossla, U. JF - Cement & Concrete (1998) Y1 - 1998 N1 - auf Japanisch SP - 146 EP - 153 ER - TY - JOUR A1 - Naithani, V. K A1 - Klostermeyer, Henning A1 - Lange, H. R. A1 - [u.a.], A1 - Berndt, Heinz A1 - [u.a.], T1 - Preparation of peptide derivatives for porcine proinsulin-synthesis JF - Biological Chemistry Y1 - 1971 U6 - http://dx.doi.org/10.1515/bchm2.1971.352.1.1 SN - 1437-4315 VL - 352 IS - 1 SP - 2 EP - 3 PB - De Gruyter ER - TY - JOUR A1 - Kotter, Michael A1 - Hammon, U. T1 - Preparation of pellets with well-defined pore structure / U. Hammon ; A. Kotter JF - International chemical engineering. 26 (1986), H. 4 Y1 - 1986 SN - 0020-6318 SP - 563 EP - 573 ER - TY - JOUR A1 - Förster, Arnold A1 - Cambel, V. A1 - Kicin, S. A1 - Kuliffayová, M. T1 - Preparation of patterned GaAs structures for MEMS and MOEMS. Cambel, V.; Kicin, S.; Kuliffayová, M.; Kovácová, E.; Novák, J.; Kostic, I.; Förster, A. JF - Materials Science and Engineering: C. 19 (2002), H. 2 Y1 - 2002 SN - 0928-4931 SP - 161 EP - 165 ER - TY - JOUR A1 - Biener, Ernst A1 - Sasse, T. A1 - Konertz, K. T1 - Preparation of mineral sealing materials for landfills by different processing technologies / Sasse, T. ; Biener, E. ; Konertz, K. JF - Sardinia 93 : Fourth International Landfill Symposium "Barrier systems, environmental aspects, upgrading and remediation, siting, monofills, effects of waste pretreatment, landfilling in developing countries" ; 11 - 15 October 1993, S. Margherita di Pula (Cagliari), Sardinia, Italy ; proceedings / coord. by Thomas H. Christensen ... - Bd. 1 Y1 - 1993 N1 - International Landfill Symposium <4, 1993, Santa Margherita, Pula> SP - 275 EP - 283 PB - CISA, Environmental Sanitary Engineering Centre CY - Cagliari ER - TY - JOUR A1 - Biselli, Manfred A1 - Schmid, Georg A1 - Wandrey, Christian T1 - Preparation of cellodextrins and isolation of oligomeric side components and their characterization / Schmid, Georg ; Biselli, Manfred ; Wandrey, Christian JF - Analytical Biochemistry. 175 (1988) Y1 - 1988 SN - 0003-2697 SP - 573 EP - 583 ER - TY - JOUR A1 - Khodaverdi, M. A1 - Pauly, F. A1 - Schroder, G. A1 - Ziemons, Karl A1 - Sievering, R. A1 - Halling, H. T1 - Preliminary studies of a micro-CT for a combined small animal PET/CT scanner JF - 2001 IEEE Nuclear Science Symposium Conference Record, Vol. 3 N2 - We are developing an X-ray computed tomography (CT) system which will be combined with a high resolution animal PET system. This permits acquisition of both molecular and anatomical images in a single machine. In particular the CT will also be utilized for the quantification of the animal PET data by providing accurate data for attenuation correction. A first prototype has been built using a commercially available plane silicon diode detector. A cone-beam reconstruction provides the images using the Feldkamp algorithm. First measurements with this system have been performed on a mouse. It could be shown that the CT setup fulfils all demands for a high quality image of the skeleton of the mouse. It is also suited for soft tissue measurements. To improve contrast and resolution and to acquire the X-ray energy further development of the system, especially the use of semiconductor detectors and iterative reconstruction algorithms are planned. Y1 - 2002 SN - 1082-3654 SP - 1605 EP - 1606 ER - TY - JOUR A1 - Biener, Ernst A1 - Sasse, T. A1 - Bökers, H. T1 - Preliminary or final capping of sanitary landfills? : Technical and economical aspects JF - Sardinia 99 : proceedings / Seventh International Waste Management and Landfill Symposium, [4 - 8 October 1999, S. Margherita di Pula, Cagliari, Sardinia, Italy]. Ed.: Thomas H. Christensen. - Bd. 3 : Barriers, waste mechanics and landfill design Y1 - 1999 N1 - International Waste Management and Landfill Symposium <7, 1999, Cagliari> SP - 287 EP - 294 PB - CISA, Environmental Sanitary Engineering Centre CY - Cagliari ER - TY - JOUR A1 - Kezerashvili, Roman Ya A1 - Dachwald, Bernd T1 - Preface: Solar sailing: Concepts, technology, and missions II JF - Advances in Space Research Y1 - 2021 U6 - http://dx.doi.org/10.1016/j.asr.2021.01.037 SN - 0273-1177 VL - 67 IS - 9 SP - 2559 EP - 2560 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Doll, Theodor A1 - Wagner, Patrick T1 - Preface / Doll, Theodor ; Wagner, Patrick ; Schöning, Michael J. JF - physica status solidi (a) . 206 (2009), H. 3 Y1 - 2009 SN - 1862-6319 N1 - Special Issue: Engineering of Functional Interfaces (EnFI 08) SP - 389 EP - 390 ER - TY - JOUR A1 - Anik, Sabri A1 - Frohberg, Martin G. A1 - Kapoor, Madan Lal T1 - Prediction of thermodynamic properties of oxygen in binary metallic solvents JF - Zeitschrift für Metallkunde Y1 - 1983 SN - 0044-3093 VL - 74 IS - 6 SP - 372 EP - 375 ER - TY - JOUR A1 - Engelmann, Ulrich M. A1 - Shasha, Carolyn A1 - Teeman, Eric A1 - Slabu, Iona A1 - Krishnan, Kannan M. T1 - Predicting size-dependent heating efficiency of magnetic nanoparticles from experiment and stochastic Néel-Brown Langevin simulation JF - Journal of Magnetism and Magnetic Materials Y1 - 2019 U6 - http://dx.doi.org/10.1016/j.jmmm.2018.09.041 SN - 0304-8853 VL - 471 IS - 1 SP - 450 EP - 456 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schelthoff, Christof A1 - Basermann, Achim A1 - Reichel, Björn T1 - Preconditioned CG methods for sparse matrices on massively parallel machines / Basermann, A. ; Reichel, B. ; Schelthoff, C. JF - Parallel Computing. 23 (1997), H. 3 Y1 - 1997 SN - 0167-8191 SP - 381 EP - 398 ER - TY - JOUR A1 - Henken, F. E. A1 - Oosterhuis, K. A1 - Öhlschläger, Peter A1 - Bosch, L. A1 - Hooijberg, E. A1 - Haanen, J. B. A. G. A1 - Steenbergen, R. D. M. T1 - Preclinical safety evaluation of DNA vaccines encoding modified HPV16 E6 and E7 JF - Vaccine N2 - Persistent infection with high-risk human papillomaviruses (hrHPV) can result in the formation of anogenital cancers. As hrHPV proteins E6 and E7 are required for cancer initiation and maintenance, they are ideal targets for immunotherapeutic interventions. Previously, we have described the development of DNA vaccines for the induction of HPV16 E6 and E7 specific T cell immunity. These vaccines consist of ‘gene-shuffled’ (SH) versions of HPV16 E6 and E7 that were fused to Tetanus Toxin Fragment C domain 1 (TTFC) and were named TTFC-E6SH and TTFC-E7SH. Gene-shuffling was performed to avoid the risk of inducing malignant transformation at the vaccination site. Here, we describe the preclinical safety evaluation of these candidate vaccines by analysis of their transforming capacity in vitro using established murine fibroblasts (NIH 3T3 cells) and primary human foreskin keratinocytes (HFKs). We demonstrate that neither ectopic expression of TTFC-E6SH and TTFC-E7SH alone or in combination enabled NIH 3T3 cells to form colonies in soft agar. In contrast, expression of HPV16 E6WT and E7WT alone or in combination resulted in effective transformation. Similarly, retroviral transduction of HFKs from three independent donors with both TTFC-E6SH and TTFC-E7SH alone or in combination did not show any signs of immortalization. In contrast, the combined expression of E6WT and E7WT induced immortalization in HFKs from all donors. Based on these results we consider it justified to proceed to clinical evaluation of DNA vaccines encoding TTFC-E6SH and TTFC-E7SH in patients with HPV16 associated (pre)malignancies. Y1 - 2012 U6 - http://dx.doi.org/10.1016/j.vaccine.2012.04.013 SN - 0264-410X VL - 30 IS - 28 SP - 4259 EP - 4266 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Oosterhuis, Koen A1 - Öhlschläger, Peter A1 - Berg, Joost H. van den A1 - Toebes, Mireille A1 - Gomez, Raquel A1 - Schumacher, Ton N. A1 - Haanen, John B. T1 - Preclinical development of highly effective and safe DNA vaccines directed against HPV 16 E6 and E7 JF - International Journal of Cancer Y1 - 2011 SN - 1097-0215 VL - 129 IS - 2 SP - 397 EP - 406 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Savitskaya, Irina A1 - Zhantlessova, Sirina A1 - Kistaubayeva, Aida A1 - Ignatova, Ludmila A1 - Shokatayeva, Dina A1 - Sinyavsky, Yuriy A1 - Kushugulova, Almagul A1 - Digel, Ilya T1 - Prebiotic cellulose–pullulan matrix as a “vehicle” for probiotic biofilm delivery to the host large intestine JF - Polymers N2 - This study describes the development of a new combined polysaccharide-matrix-based technology for the immobilization of Lactobacillus rhamnosus GG (LGG) bacteria in biofilm form. The new composition allows for delivering the bacteria to the digestive tract in a manner that improves their robustness compared with planktonic cells and released biofilm cells. Granules consisting of a polysaccharide matrix with probiotic biofilms (PMPB) with high cell density (>9 log CFU/g) were obtained by immobilization in the optimized nutrient medium. Successful probiotic loading was confirmed by fluorescence microscopy and scanning electron microscopy. The developed prebiotic polysaccharide matrix significantly enhanced LGG viability under acidic (pH 2.0) and bile salt (0.3%) stress conditions. Enzymatic extract of feces, mimicking colon fluid in terms of cellulase activity, was used to evaluate the intestinal release of probiotics. PMPB granules showed the ability to gradually release a large number of viable LGG cells in the model colon fluid. In vivo, the oral administration of PMPB granules in rats resulted in the successful release of probiotics in the colon environment. The biofilm-forming incubation method of immobilization on a complex polysaccharide matrix tested in this study has shown high efficacy and promising potential for the development of innovative biotechnologies. KW - immobilization KW - prebiotic KW - bacterial cellulose KW - biofilms KW - Lactobacillus rhamnosus GG Y1 - 2023 U6 - http://dx.doi.org/10.3390/polym16010030 N1 - This article belongs to the Section "Polymer Composites and Nanocomposites" IS - 16(1) PB - MDPI CY - Basel ER - TY - JOUR A1 - Gebhardt, Andreas A1 - Schmidt, Frank-Michael T1 - Practical experiences with making and finishing of coloured models using 3D printing Y1 - 2002 N1 - International Conference on Rapid Prototyping and Manufacturing <2, 2002, Beijing> ER - TY - JOUR A1 - Funke, Harald A1 - Esch, Thomas A1 - Roosen, Petra T1 - Powertrain Adaptions for LPG Usage in General Aviation JF - MTZ worldwide N2 - In general aviation, too, it is desirable to be able to operate existing internal combustion engines with fuels that produce less CO₂ than Avgas 100LL being widely used today It can be assumed that, in comparison, the fuels CNG, LPG or LNG, which are gaseous under normal conditions, produce significantly lower emissions. Necessary propulsion system adaptations were investigated as part of a research project at Aachen University of Applied Sciences. Y1 - 2022 U6 - http://dx.doi.org/10.1007/s38313-021-0756-6 VL - 2022 IS - 83 SP - 58 EP - 62 PB - Springer Nature CY - Basel ER - TY - JOUR A1 - Yoshinobu, T. A1 - Ui, Y. A1 - Iwasaki, H. A1 - Näther, Niko A1 - Koudelka-Hep, M. A1 - Schöning, Michael Josef T1 - Potentiometric imaging in a microfluidic channel JF - Biomedizinische Technik. 49 (2004), H. 2 Y1 - 2004 SN - 0932-4666 SP - 998 EP - 999 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Seboldt, Wolfgang A1 - Macdonald, Malcolm A1 - Mengali, Giovanni A1 - Quatra, Alessandro A. A1 - McInnes, Colin R. A1 - Rios-Reyes, Leonel A1 - Scheerers, Daniel J. A1 - Wie, Bong A1 - Görlich, Marianne A1 - Lura, Franz A1 - Diedrich, Benjamin A1 - Baturkin, Volodymyr A1 - Coverstone, Victoria L. A1 - Leipold, Manfred A1 - Garbe, Gregory P. T1 - Potential Solar Sail Degradation Effects on Trajectory and Attitude Control JF - AIAA Guidance, Navigation and Control Conference and Exhibit - AIAA Modeling and Simulation Technologies Conference and Exhibit - AIAA Atmospheric Flight Mechanics Conference and Exhibit : [San Francisco, California, 15 - 18 August 2005 ; papers]. - (AIAA meeting papers on disc ; [10.]2005,16-17) Y1 - 2005 SN - 1-56347-765-3 N1 - American Institute of Aeronautics and Astronautics ; AIAA Guidance, Navigation, and Control Conference and Exhibit <2005, San Francisco, Calif.> ; AIAA paper number: AIAA-2006-6172 Link "https://arc.aiaa.org/doi/book/10.2514/MGNC05" am 15.07.2022 nachgetragen Behr PB - American Institute of Aeronautics and Astronautics CY - Reston, Va. ER - TY - JOUR A1 - Dachwald, Bernd A1 - Baturkin, Volodymyr A1 - Coverstone, Victoria L. A1 - Dietrich, Benjamin A1 - Garbe, Gregory P. A1 - Görlich, Marianne A1 - Leipold, Manfred A1 - Lura, Franz A1 - Macdonald, Malcolm A1 - McInnes, Colin R. A1 - Mengali, Giovanni A1 - Quatra, Alessandro A. A1 - Rios-Reyes, Leonel A1 - Scheeres, Daniel J. A1 - Seboldt, Wolfgang A1 - Wie, Bong T1 - Potential Effects of Optical Solar Sail Degradation on Interplanetary Trajectory Design JF - Astrodynamics 2005 : proceedings of the AAS/AIAA astrodynamics conference held August 7 - 11, 2005, South Lake Tahoe, California / ed. by Bobby G. Williams. - Pt. 3. - (Advances in the astronautical sciences ; 123,3) Y1 - 2006 UR - http://www.spacesailing.net/paper/200508_LakeTahoe_Dachwald+.pdf SN - 0-87703-527-X N1 - Astrodynamics Conference <2005, South Lake Tahoe, Calif.> ; American Astronautical Society ; Number: AAS-05-413 SP - 2569 EP - 2592 PB - Univelt CY - San Diego, Calif. 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