TY - CHAP A1 - Serror, Martin A1 - Henze, Martin A1 - Hack, Sacha A1 - Schuba, Marko A1 - Wehrle, Klaus T1 - Towards in-network security for smart homes T2 - 13th International Conference on Availability, Reliability and Security, ARES 2018; Hamburg; Germany; 27 August 2018 through 30 August 2018 Y1 - 2018 SN - 978-145036448-5 U6 - https://doi.org/10.1145/3230833.3232802 SP - Article numer 3232802 ER - TY - CHAP A1 - Krome, Cornelia A1 - Sander, Volker T1 - Time series analysis with apache spark and its applications to energy informatics T2 - Proceedings of the 7th DACH+ Conference on Energy Informatics N2 - In energy economy forecasts of different time series are rudimentary. In this study, a prediction for the German day-ahead spot market is created with Apache Spark and R. It is just an example for many different applications in virtual power plant environments. Other examples of use as intraday price processes, load processes of machines or electric vehicles, real time energy loads of photovoltaic systems and many more time series need to be analysed and predicted. This work gives a short introduction into the project where this study is settled. It describes the time series methods that are used in energy industry for forecasts shortly. As programming technique Apache Spark, which is a strong cluster computing technology, is utilised. Today, single time series can be predicted. The focus of this work is on developing a method to parallel forecasting, to process multiple time series simultaneously with R and Apache Spark. Y1 - 2018 U6 - https://doi.org/10.1186/s42162-018-0043-1 N1 - Energy Informatics 2018, Volume 1 Supplement 1 ER - TY - CHAP A1 - Müller, Tim M. A1 - Altherr, Lena A1 - Ahola, Marja A1 - Schabel, Samuel A1 - Pelz, Peter F. T1 - Optimizing pressure screen systems in paper recycling: optimal system layout, component selection and operation N2 - Around 60% of the paper worldwide is made from recovered paper. Especially adhesive contaminants, so called stickies, reduce paper quality. To remove stickies but at the same time keep as many valuable fibers as possible, multi-stage screening systems with several interconnected pressure screens are used. When planning such systems, suitable screens have to be selected and their interconnection as well as operational parameters have to be defined considering multiple conflicting objectives. In this contribution, we present a Mixed-Integer Nonlinear Program to optimize system layout, component selection and operation to find a suitable trade-off between output quality and yield. KW - Mixed-integer nonlinear problem KW - MINLP KW - Process engineering KW - Paper recycling KW - Multi-criteria optimization Y1 - 2018 SN - 978-3-030-18499-5 U6 - https://doi.org/10.1007/978-3-030-18500-8_44 SP - 355 EP - 361 PB - Springer CY - Cham ER - TY - JOUR A1 - Sun, Hui A1 - Altherr, Lena A1 - Pei, Ji A1 - Pelz, Peter F. A1 - Yuan, Shouqi T1 - Optimal booster station design and operation under uncertain load JF - Applied Mechanics and Materials N2 - Given industrial applications, the costs for the operation and maintenance of a pump system typically far exceed its purchase price. For finding an optimal pump configuration which minimizes not only investment, but life-cycle costs, methods like Technical Operations Research which is based on Mixed-Integer Programming can be applied. However, during the planning phase, the designer is often faced with uncertain input data, e.g. future load demands can only be estimated. In this work, we deal with this uncertainty by developing a chance-constrained two-stage (CCTS) stochastic program. The design and operation of a booster station working under uncertain load demand are optimized to minimize total cost including purchase price, operation cost incurred by energy consumption and penalty cost resulting from water shortage. We find optimized system layouts using a sample average approximation (SAA) algorithm, and analyze the results for different risk levels of water shortage. By adjusting the risk level, the costs and performance range of the system can be balanced, and thus the system’s resilience can be engineered KW - Stochastic Programming KW - Chance Constraint KW - Engineering Application KW - Pump System KW - Water Distribution Y1 - 2018 U6 - https://doi.org/10.4028/www.scientific.net/AMM.885.102 SN - 1662-7482 VL - 885 SP - 102 EP - 115 PB - Trans Tech Publications CY - Bäch ER - TY - CHAP A1 - Leise, Philipp A1 - Altherr, Lena T1 - Optimizing the design and control of decentralized water supply systems – a case-study of a hotel building T2 - EngOpt 2018 Proceedings of the 6th International Conference on Engineering Optimization N2 - To increase pressure to supply all floors of high buildings with water, booster stations, normally consisting of several parallel pumps in the basement, are used. In this work, we demonstrate the potential of a decentralized pump topology regarding energy savings in water supply systems of skyscrapers. We present an approach, based on Mixed-Integer Nonlinear Programming, that allows to choose an optimal network topology and optimal pumps from a predefined construction kit comprising different pump types. Using domain-specific scaling laws and Latin Hypercube Sampling, we generate different input sets of pump types and compare their impact on the efficiency and cost of the total system design. As a realistic application example, we consider a hotel building with 325 rooms, 12 floors and up to four pressure zones. KW - Engineering optimization KW - Energy efficiency KW - Water KW - Pump System KW - Latin Hypercube Sampling Y1 - 2018 SN - 978-3-319-97773-7 SN - 978-3-319-97772-0 U6 - https://doi.org/10.1007/978-3-319-97773-7_107 N1 - EngOpt 2018 Proceedings of the 6th International Conference on Engineering Optimization. 17-19 September 2018. Lisboa, Portugal SP - 1241 EP - 1252 PB - Springer CY - Cham ER - TY - CHAP A1 - Stenger, David A1 - Altherr, Lena A1 - Müller, Tankred A1 - Pelz, Peter F. T1 - Product family design optimization using model-based engineering techniques T2 - Operations Research Proceedings 2017 N2 - Highly competitive markets paired with tremendous production volumes demand particularly cost efficient products. The usage of common parts and modules across product families can potentially reduce production costs. Yet, increasing commonality typically results in overdesign of individual products. Multi domain virtual prototyping enables designers to evaluate costs and technical feasibility of different single product designs at reasonable computational effort in early design phases. However, savings by platform commonality are hard to quantify and require detailed knowledge of e.g. the production process and the supply chain. Therefore, we present and evaluate a multi-objective metamodel-based optimization algorithm which enables designers to explore the trade-off between high commonality and cost optimal design of single products. Y1 - 2018 SN - 978-3-319-89919-0 U6 - https://doi.org/10.1007/978-3-319-89920-6_66 SP - 495 EP - 502 PB - Springer CY - Cham ER - TY - JOUR A1 - Altherr, Lena A1 - Brötz, Nicolas A1 - Dietrich, Ingo A1 - Gally, Tristan A1 - Geßner, Felix A1 - Kloberdanz, Hermann A1 - Leise, Philipp A1 - Pelz, Peter Franz A1 - Schlemmer, Pia A1 - Schmitt, Andreas T1 - Resilience in mechanical engineering - a concept for controlling uncertainty during design, production and usage phase of load-carrying structures JF - Applied Mechanics and Materials N2 - Resilience as a concept has found its way into different disciplines to describe the ability of an individual or system to withstand and adapt to changes in its environment. In this paper, we provide an overview of the concept in different communities and extend it to the area of mechanical engineering. Furthermore, we present metrics to measure resilience in technical systems and illustrate them by applying them to load-carrying structures. By giving application examples from the Collaborative Research Centre (CRC) 805, we show how the concept of resilience can be used to control uncertainty during different stages of product life. Y1 - 2018 SN - 1662-7482 U6 - https://doi.org/10.4028/www.scientific.net/AMM.885.187 VL - 885 SP - 187 EP - 198 PB - Trans Tech Publications CY - Bäch ER - TY - CHAP A1 - Leise, Philipp A1 - Altherr, Lena A1 - Pelz, Peter F. T1 - Technical Operations Research (TOR) - Algorithms, not Engineers, Design Optimal Energy Efficient and Resilient Cooling Systems T2 - FAN2018 - Proceedings of the International Conference on Fan Noise, Aerodynamics, Applications and Systems N2 - The overall energy efficiency of ventilation systems can be improved by considering not only single components, but by considering as well the interplay between every part of the system. With the help of the method "TOR" ("Technical Operations Research"), which was developed at the Chair of Fluid Systems at TU Darmstadt, it is possible to improve the energy efficiency of the whole system by considering all possible design choices programmatically. We show the ability of this systematic design approach with a ventilation system for buildings as a use case example. Based on a Mixed-Integer Nonlinear Program (MINLP) we model the ventilation system. We use binary variables to model the selection of different pipe diameters. Multiple fans are model with the help of scaling laws. The whole system is represented by a graph, where the edges represent the pipes and fans and the nodes represents the source of air for cooling and the sinks, that have to be cooled. At the beginning, the human designer chooses a construction kit of different suitable fans and pipes of different diameters and different load cases. These boundary conditions define a variety of different possible system topologies. It is not possible to consider all topologies by hand. With the help of state of the art solvers, on the other side, it is possible to solve this MINLP. Next to this, we also consider the effects of malfunctions in different components. Therefore, we show a first approach to measure the resilience of the shown example use case. Further, we compare the conventional approach with designs that are more resilient. These more resilient designs are derived by extending the before mentioned model with further constraints, that consider explicitly the resilience of the overall system. We show that it is possible to design resilient systems with this method already in the early design stage and compare the energy efficiency and resilience of these different system designs. Y1 - 2018 N1 - International Conference on Fan Noise, Aerodynamics, Applications and Systems 18-20.04.2018 Darmstadt, Deutschland SP - 1 EP - 12 ER - TY - CHAP A1 - Leise, Philipp A1 - Altherr, Lena A1 - Pelz, Peter F. T1 - Energy-Efficient design of a water supply system for skyscrapers by mixed-integer nonlinear programming T2 - Operations Research Proceedings 2017 N2 - The energy-efficiency of technical systems can be improved by a systematic design approach. Technical Operations Research (TOR) employs methods known from Operations Research to find a global optimal layout and operation strategy of technical systems. We show the practical usage of this approach by the systematic design of a decentralized water supply system for skyscrapers. All possible network options and operation strategies are modeled by a Mixed-Integer Nonlinear Program. We present the optimal system found by our approach and highlight the energy savings compared to a conventional system design. KW - Engineering optimization KW - Global optimization KW - Energy efficiency KW - Water KW - Network Y1 - 2018 SN - 978-3-319-89919-0 U6 - https://doi.org/10.1007/978-3-319-89920-6_63 PB - Springer CY - Cham ER - TY - CHAP A1 - Rausch, Lea A1 - Friesen, John A1 - Altherr, Lena A1 - Pelz, Peter F. ED - Kliewer, Natalia ED - Ehmke, Jan Fabian ED - Borndörfer, Ralf T1 - Using mixed-integer programming for the optimal design of water supply networks for slums T2 - Operations Research Proceedings 2017 N2 - The UN sets the goal to ensure access to water and sanitation for all people by 2030. To address this goal, we present a multidisciplinary approach for designing water supply networks for slums in large cities by applying mathematical optimization. The problem is modeled as a mixed-integer linear problem (MILP) aiming to find a network describing the optimal supply infrastructure. To illustrate the approach, we apply it on a small slum cluster in Dhaka, Bangladesh. Y1 - 2018 SN - 978-3-319-89919-0 (Print) SN - 978-3-319-89920-6 (Online) U6 - https://doi.org/10.1007/978-3-319-89920-6_68 N1 - International Conference of the German Operations Research Society (GOR), Freie Universiät Berlin, Germany, September 6-8, 2017. SP - 509 EP - 516 PB - Springer CY - Cham ER - TY - JOUR A1 - Rausch, Lea A1 - Friesen, John A1 - Altherr, Lena A1 - Meck, Marvin A1 - Pelz, Peter F. T1 - A holistic concept to design optimal water supply infrastructures for informal settlements using remote sensing data JF - Remote Sensing N2 - Ensuring access to water and sanitation for all is Goal No. 6 of the 17 UN Sustainability Development Goals to transform our world. As one step towards this goal, we present an approach that leverages remote sensing data to plan optimal water supply networks for informal urban settlements. The concept focuses on slums within large urban areas, which are often characterized by a lack of an appropriate water supply. We apply methods of mathematical optimization aiming to find a network describing the optimal supply infrastructure. Hereby, we choose between different decentral and central approaches combining supply by motorized vehicles with supply by pipe systems. For the purposes of illustration, we apply the approach to two small slum clusters in Dhaka and Dar es Salaam. We show our optimization results, which represent the lowest cost water supply systems possible. Additionally, we compare the optimal solutions of the two clusters (also for varying input parameters, such as population densities and slum size development over time) and describe how the result of the optimization depends on the entered remote sensing data. KW - water supply design KW - mathematical optimization KW - slum classification KW - remote sensing Y1 - 2018 SN - 2072-4292 U6 - https://doi.org/10.3390/rs10020216 VL - 10 IS - 2 SP - 1 EP - 23 PB - MDPI CY - Basel ER - TY - JOUR A1 - Altherr, Lena A1 - Joggerst, Laura A1 - Leise, Philipp A1 - Pfetsch, Marc E. A1 - Schmitt, Andreas A1 - Wendt, Janine T1 - On obligations in the development process of resilient systems with algorithmic design methods JF - Applied Mechanics and Materials N2 - Advanced computational methods are needed both for the design of large systems and to compute high accuracy solutions. Such methods are efficient in computation, but the validation of results is very complex, and highly skilled auditors are needed to verify them. We investigate legal questions concerning obligations in the development phase, especially for technical systems developed using advanced methods. In particular, we consider methods of resilient and robust optimization. With these techniques, high performance solutions can be found, despite a high variety of input parameters. However, given the novelty of these methods, it is uncertain whether legal obligations are being met. The aim of this paper is to discuss if and how the choice of a specific computational method affects the developer’s product liability. The review of legal obligations in this paper is based on German law and focuses on the requirements that must be met during the design and development process. KW - legal obligations KW - product liability KW - design of technical systems KW - optimization KW - resilience Y1 - 2018 SN - 1662-7482 U6 - https://doi.org/10.4028/www.scientific.net/AMM.885.240 VL - 885 IS - 885 SP - 240 EP - 252 PB - Trans Tech Publications CY - Bäch ER - TY - CHAP A1 - Bensberg, Frank A1 - Auth, Gunnar A1 - Czarnecki, Christian A1 - Wörndle, Christopher ED - Kemal İlter, H. T1 - Transforming literature-intensive research processes through text analytics – design, implementation and lessons learned N2 - The continuing growth of scientific publications raises the question how research processes can be digitalized and thus realized more productively. Especially in information technology fields, research practice is characterized by a rapidly growing volume of publications. For the search process various information systems exist. However, the analysis of the published content is still a highly manual task. Therefore, we propose a text analytics system that allows a fully digitalized analysis of literature sources. We have realized a prototype by using EBSCO Discovery Service in combination with IBM Watson Explorer and demonstrated the results in real-life research projects. Potential addressees are research institutions, consulting firms, and decision-makers in politics and business practice. KW - Text analytics KW - Text mining KW - Literature review KW - Research process Y1 - 2018 U6 - https://doi.org/10.6084/m9.figshare.7582073.v1 N1 - 5th International Management Information Systems Conference. October 24-26 2018, Ankara ER - TY - CHAP A1 - Brockmann, Carsten A1 - Sultanow, Eldar A1 - Czarnecki, Christian ED - Czarnecki, Christian ED - Brockmann, Carsten ED - Sultanow, Eldar ED - Koschmider, Agnes ED - Selzer, Annika ED - Gesellschaft für Informatik e. V., T1 - Enterprise architectures between agility and traditional methodologies T2 - GI Edition Proceedings Band 285 Workshops der INFORMATIK 2018 N2 - For this year’s workshop on Enterpirse Architecture in Research and Practice we have received eight submissions from which four have passed the rigorous peer-review. The acceptance quote of 50% assures that only advancements in the field are included in our workshop. KW - Agility KW - agile KW - Enterprise Architecture Y1 - 2018 SN - 9783885796794 SN - 1617-5468 N1 - 26.-27. September 2018 Berlin PB - Köllen CY - Bonn ER - TY - CHAP A1 - Czarnecki, Christian ED - vom Brocke, Jan ED - Mendling, Jan T1 - Establishment of a central process governance organization combined with operational process improvements : Insights from a BPM Project at a leading telecommunications operator in the Middle East T2 - Business process management cases : digital innovation and business transformation in practice N2 - Because of customer churn, strong competition, and operational inefficiencies, the telecommunications operator ME Telco (fictitious name due to confidentiality) launched a strategic transformation program that included a Business Process Management (BPM) project. Major problems were silo-oriented process management and missing cross-functional transparency. Process improvements were not consistently planned and aligned with corporate targets. Measurable inefficiencies were observed on an operational level, e.g., high lead times and reassignment rates of the incident management process. Y1 - 2018 SN - 978-3-319-58306-8 SN - 978-3-319-58307-5 SN - 978-3-319-86372-6 U6 - https://doi.org/10.1007/978-3-319-58307-5 N1 - Als Präsenzexemplar unter der Signatur 20 PZR 469-1 vorhanden. SP - 57 EP - 76 PB - Springer CY - Cham ER - TY - JOUR A1 - Figueroa-Miranda, Gabriela A1 - Feng, Lingyan A1 - Shiu, Simon Chi-Chin A1 - Dirkzwager, Roderick Marshall A1 - Cheung, Yee-Wai A1 - Tanner, Julian Alexander A1 - Schöning, Michael Josef A1 - Offenhäusser, Andreas A1 - Mayer, Dirk T1 - Aptamer-based electrochemical biosensor for highly sensitive and selective malaria detection with adjustable dynamic response range and reusability JF - Sensor and Actuators B: Chemical N2 - Malaria infection remains a significant risk for much of the population of tropical and subtropical areas, particularly in developing countries. Therefore, it is of high importance to develop sensitive, accurate and inexpensive malaria diagnosis tests. Here, we present a novel aptamer-based electrochemical biosensor (aptasensor) for malaria detection by impedance spectroscopy, through the specific recognition between a highly discriminatory DNA aptamer and its target Plasmodium falciparum lactate dehydrogenase (PfLDH). Interestingly, due to the isoelectric point (pI) of PfLDH, the aptasensor response showed an adjustable detection range based on the different protein net-charge at variable pH environments. The specific aptamer recognition allows sensitive protein detection with an expanded detection range and a low detection limit, as well as a high specificity for PfLDH compared to analogous proteins. The specific feasibility of the aptasensor is further demonstrated by detection of the target PfLDH in human serum. Furthermore, the aptasensor can be easily regenerated and thus applied for multiple usages. The robustness, sensitivity, and reusability of the presented aptasensor make it a promising candidate for point-of-care diagnostic systems. Y1 - 2018 U6 - https://doi.org/10.1016/j.snb.2017.07.117 SN - 0925-4005 VL - 255 IS - P1 SP - 235 EP - 243 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Engemann, Heiko A1 - Wiesen, Patrick A1 - Kallweit, Stephan A1 - Deshpande, Harshavardhan A1 - Schleupen, Josef T1 - Autonomous mobile manipulation using ROS T2 - Advances in Service and Industrial Robotics Y1 - 2018 SN - 978-3-319-61276-8 U6 - https://doi.org/10.1007/978-3-319-61276-8_43 N1 - International Conference on Robotics in Alpe-Adria Danube Region RAAD 2017; Mechanisms and Machince Science book series, Vol 49. SP - 389 EP - 401 PB - Springer CY - Cham ER - TY - JOUR A1 - Miyamoto, Koichiro A1 - Seki, Kosuke A1 - Suto, Takeyuki A1 - Werner, Frederik A1 - Wagner, Torsten A1 - Schöning, Michael Josef A1 - Yoshinobu, Tatsuo T1 - Improved spatial resolution of the chemical imaging sensor with a hybrid illumination that suppresses lateral diffusion of photocarriers JF - Sensor and Actuators B: Chemical N2 - The chemical imaging sensor is a semiconductor-based chemical sensor capable of visualizing pH and ion distributions. The spatial resolution depends on the lateral diffusion of photocarriers generated by illumination of the semiconductor substrate. In this study, two types of optical setups, one based on a bundle of optical fibers and the other based on a binocular tube head, were developed to project a hybrid illumination of a modulated light beam and a ring-shaped constant illumination onto the sensor plate. An improved spatial resolution was realized by the ring-shaped constant illumination, which suppressed lateral diffusion of photocarriers by enhanced recombination due to the increased carrier concentration. Y1 - 2018 U6 - https://doi.org/10.1016/j.snb.2018.07.016 SN - 0925-4005 VL - 273 SP - 1328 EP - 1333 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Eckert, Alexander A1 - Rudolph, Tobias A1 - Guo, Jiaqi A1 - Mang, Thomas A1 - Walther, Andreas T1 - Exceptionally Ductile and Tough Biomimetic Artificial Nacre with Gas Barrier Function JF - Advanced Materials N2 - Synthetic mimics of natural high-performance structural materials have shown great and partly unforeseen opportunities for the design of multifunctional materials. For nacre-mimetic nanocomposites, it has remained extraordinarily challenging to make ductile materials with high stretchability at high fractions of reinforcements, which is however of crucial importance for flexible barrier materials. Here, highly ductile and tough nacre-mimetic nanocomposites are presented, by implementing weak, but many hydrogen bonds in a ternary nacre-mimetic system consisting of two polymers (poly(vinyl amine) and poly(vinyl alcohol)) and natural nanoclay (montmorillonite) to provide efficient energy dissipation and slippage at high nanoclay content (50 wt%). Tailored interactions enable exceptional combinations of ductility (close to 50% strain) and toughness (up to 27.5 MJ m⁻³). Extensive stress whitening, a clear sign of high internal dynamics at high internal cohesion, can be observed during mechanical deformation, and the materials can be folded like paper into origami planes without fracture. Overall, the new levels of ductility and toughness are unprecedented in highly reinforced bioinspired nanocomposites and are of critical importance to future applications, e.g., as barrier materials needed for encapsulation and as a printing substrate for flexible organic electronics. Y1 - 2018 U6 - https://doi.org/10.1002/adma.201802477 VL - 30 IS - 32 SP - Article number 1802477 PB - Wiley-VCH ER - TY - JOUR A1 - Lapitan, Denis G. A1 - Rogatkin, Dmitrii A. A1 - Persheyev, Sydulla K. A1 - Kotliar, Konstantin T1 - False spectra formation in the differential two-channel scheme of the laser Doppler flowmeter JF - Biomedizinische Technik N2 - Noise in the differential two-channel scheme of a classic laser Doppler flowmetry (LDF) instrument was studied. Formation of false spectral components in the output signal due to beating of electrical signals in the differential amplifier was found out. The improved block-diagram of the flowmeter was developed allowing to reduce the noise. Y1 - 2018 U6 - https://doi.org/10.1515/bmt-2017-0060 SN - 0013-5585 VL - 63 IS - 4 SP - 439 EP - 444 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Röhlen, Desiree A1 - Pilas, Johanna A1 - Dahmen, Markus A1 - Keusgen, Michael A1 - Selmer, Thorsten A1 - Schöning, Michael Josef T1 - Toward a Hybrid Biosensor System for Analysis of Organic and Volatile Fatty Acids in Fermentation Processes JF - Frontiers in Chemistry N2 - Monitoring of organic acids (OA) and volatile fatty acids (VFA) is crucial for the control of anaerobic digestion. In case of unstable process conditions, an accumulation of these intermediates occurs. In the present work, two different enzyme-based biosensor arrays are combined and presented for facile electrochemical determination of several process-relevant analytes. Each biosensor utilizes a platinum sensor chip (14 × 14 mm²) with five individual working electrodes. The OA biosensor enables simultaneous measurement of ethanol, formate, d- and l-lactate, based on a bi-enzymatic detection principle. The second VFA biosensor provides an amperometric platform for quantification of acetate and propionate, mediated by oxidation of hydrogen peroxide. The cross-sensitivity of both biosensors toward potential interferents, typically present in fermentation samples, was investigated. The potential for practical application in complex media was successfully demonstrated in spiked sludge samples collected from three different biogas plants. Thereby, the results obtained by both of the biosensors were in good agreement to the applied reference measurements by photometry and gas chromatography, respectively. The proposed hybrid biosensor system was also used for long-term monitoring of a lab-scale biogas reactor (0.01 m³) for a period of 2 months. In combination with typically monitored parameters, such as gas quality, pH and FOS/TAC (volatile organic acids/total anorganic carbonate), the amperometric measurements of OA and VFA concentration could enhance the understanding of ongoing fermentation processes. Y1 - 2018 U6 - https://doi.org/10.3389/fchem.2018.00284 IS - 6 PB - Frontiers CY - Lausanne ER - TY - JOUR A1 - Rodrigues, Raul T. A1 - Morais, Paulo V. A1 - Nordi, Cristina S. F. A1 - Schöning, Michael Josef A1 - Siqueira Jr., José R. A1 - Caseli, Luciano T1 - Carbon Nanotubes and Algal Polysaccharides To Enhance the Enzymatic Properties of Urease in Lipid Langmuir-Blodgett Films JF - Langmuir N2 - Algal polysaccharides (extracellular polysaccharides) and carbon nanotubes (CNTs) were adsorbed on dioctadecyldimethylammonium bromide Langmuir monolayers to serve as a matrix for the incorporation of urease. The physicochemical properties of the supramolecular system as a monolayer at the air–water interface were investigated by surface pressure–area isotherms, surface potential–area isotherms, interfacial shear rheology, vibrational spectroscopy, and Brewster angle microscopy. The floating monolayers were transferred to hydrophilic solid supports, quartz, mica, or capacitive electrolyte–insulator–semiconductor (EIS) devices, through the Langmuir–Blodgett (LB) technique, forming mixed films, which were investigated by quartz crystal microbalance, fluorescence spectroscopy, and field emission gun scanning electron microscopy. The enzyme activity was studied with UV–vis spectroscopy, and the feasibility of the thin film as a urea sensor was essayed in an EIS sensor device. The presence of CNT in the enzyme–lipid LB film not only tuned the catalytic activity of urease but also helped to conserve its enzyme activity. Viability as a urease sensor was demonstrated with capacitance–voltage and constant capacitance measurements, exhibiting regular and distinctive output signals over all concentrations used in this work. These results are related to the synergism between the compounds on the active layer, leading to a surface morphology that allowed fast analyte diffusion owing to an adequate molecular accommodation, which also preserved the urease activity. This work demonstrates the feasibility of employing LB films composed of lipids, CNT, algal polysaccharides, and enzymes as EIS devices for biosensing applications. Y1 - 2018 U6 - https://doi.org/10.1021/acs.langmuir.7b04317 SN - 1520-5827 VL - 34 IS - 9 SP - 3082 EP - 3093 PB - ACS Publications CY - Washington, DC ER - TY - JOUR A1 - Albanna, Walid A1 - Kotliar, Konstantin A1 - Lüke, Jan Niklas A1 - Alpdogan, Serdar A1 - Conzen, Catharina A1 - Lindauer, Ute A1 - Clusmann, Hans A1 - Hescheler, Jürgen A1 - Vilser, Walthard A1 - Schneider, Toni A1 - Schubert, Gerrit Alexander T1 - Non-invasive evaluation of neurovascular coupling in the murine retina by dynamic retinal vessel analysis JF - Plos one N2 - Background Impairment of neurovascular coupling (NVC) was recently reported in the context of subarachnoid hemorrhage and may correlate with disease severity and outcome. However, previous techniques to evaluate NVC required invasive procedures. Retinal vessels may represent an alternative option for non-invasive assessment of NVC. Methods A prototype of an adapted retinal vessel analyzer was used to assess retinal vessel diameter in mice. Dynamic vessel analysis (DVA) included an application of monochromatic flicker light impulses in predefined frequencies for evaluating NVC. All retinae were harvested after DVA and electroretinograms were performed. Results A total of 104 retinal scans were conducted in 21 male mice (90 scans). Quantitative arterial recordings were feasible only in a minority of animals, showing an emphasized reaction to flicker light impulses (8 mice; 14 scans). A characteristic venous response to flicker light, however, could observed in the majority of animals. Repeated measurements resulted in a significant decrease of baseline venous diameter (7 mice; 7 scans, p < 0.05). Ex-vivo electroretinograms, performed after in-vivo DVA, demonstrated a significant reduction of transretinal signaling in animals with repeated DVA (n = 6, p < 0.001). Conclusions To the best of our knowledge, this is the first non-invasive study assessing murine retinal vessel response to flicker light with characteristic changes in NVC. The imaging system can be used for basic research and enables the investigation of retinal vessel dimension and function in control mice and genetically modified animals. Y1 - 2018 U6 - https://doi.org/10.1371/journal.pone.0204689 VL - 13 IS - 10 PB - PLOS CY - San Francisco ER - TY - JOUR A1 - Tekin, Nurettin A1 - Ashikaga, Mitsugu A1 - Horikawa, Atsushi A1 - Funke, Harald T1 - Enhancement of fuel flexibility of industrial gas turbines by development of innovative hydrogen combustion systems JF - Gas for energy N2 - For fuel flexibility enhancement hydrogen represents a possible alternative gas turbine fuel within future low emission power generation, in case of hydrogen production by the use of renewable energy sources such as wind energy or biomass. Kawasaki Heavy Industries, Ltd. (KHI) has research and development projects for future hydrogen society; production of hydrogen gas, refinement and liquefaction for transportation and storage, and utilization with gas turbine / gas engine for the generation of electricity. In the development of hydrogen gas turbines, a key technology is the stable and low NOx hydrogen combustion, especially Dry Low Emission (DLE) or Dry Low NOx (DLN) hydrogen combustion. Due to the large difference in the physical properties of hydrogen compared to other fuels such as natural gas, well established gas turbine combustion systems cannot be directly applied for DLE hydrogen combustion. Thus, the development of DLE hydrogen combustion technologies is an essential and challenging task for the future of hydrogen fueled gas turbines. The DLE Micro-Mix combustion principle for hydrogen fuel has been in development for many years to significantly reduce NOx emissions. This combustion principle is based on cross-flow mixing of air and gaseous hydrogen which reacts in multiple miniaturized “diffusion-type” flames. The major advantages of this combustion principle are the inherent safety against flashback and the low NOx-emissions due to a very short residence time of the reactants in the flame region of the micro-flames. Y1 - 2018 IS - 2 PB - Vulkan-Verlag CY - Essen ER - TY - JOUR A1 - Balakirski, Galina A1 - Kotliar, Konstantin A1 - Pauly, Karolin J. A1 - Krings, Laura K. A1 - Rübben, Albert A1 - Baron, Jens M. A1 - Schmitt, Laurenz T1 - Surgical Site Infections After Dermatologic Surgery in Immunocompromised Patients: A Single-Center Experience JF - Dermatologic Surgery N2 - BACKGROUND Immunosuppression is often considered as an indication for antibiotic prophylaxis to prevent surgical site infections (SSI) while performing skin surgery. However, the data on the risk of developing SSI after dermatologic surgery in immunosuppressed patients are limited. PATIENTS AND METHODS All patients of the Department of Dermatology and Allergology at the University Hospital of RWTH Aachen in Aachen, Germany, who underwent hospitalization for a dermatologic surgery between June 2016 and January 2017 (6 months), were followed up after surgery until completion of the wound healing process. The follow-up addressed the occurrence of SSI and the need for systemic antibiotics after the operative procedure. Immunocompromised patients were compared with immunocompetent patients. The investigation was conducted as a retrospective analysis of patient records. RESULTS The authors performed 284 dermatologic surgeries in 177 patients. Nineteen percent (54/284) of the skin surgery was performed on immunocompromised patients. The most common indications for surgical treatment were nonmelanoma skin cancer and malignant melanomas. Surgical site infections occurred in 6.7% (19/284) of the cases. In 95% (18/19), systemic antibiotic treatment was needed. Twenty-one percent of all SSI (4/19) were seen in immunosuppressed patients. CONCLUSION According to the authors' data, immunosuppression does not represent a significant risk factor for SSI after dermatologic surgery. However, larger prospective studies are needed to make specific recommendations on the use of antibiotic prophylaxis while performing skin surgery in these patients. The available data on complications after dermatologic surgery have improved over the past years. Particularly, additional risk factors have been identified for surgical site infections (SSI). Purulent surgical sites, older age, involvement of head, neck, and acral regions, and also the involvement of less experienced surgeons have been reported to increase the risk of the SSI after dermatologic surgeries.1 In general, the incidence of SSI after skin surgery is considered to be low.1,2 However, antibiotics in dermatologic surgeries, especially in the perioperative setting, seem to be overused,3,4 particularly regarding developing antibiotic resistances and side effects. Immunosuppression has been recommended to be taken into consideration as an additional indication for antibiotic prophylaxis to prevent SSI after skin surgery in special cases.5,6 However, these recommendations do not specify the exact dermatologic surgeries, and were not specifically developed for dermatologic surgery patients and treatments, but adopted from other surgical fields.6 According to the survey conducted on American College of Mohs Surgery members in 2012, 13% to 29% of the surgeons administered antibiotic prophylaxis to immunocompromised patients to prevent SSI while performing dermatologic surgery on noninfected skin,3 although this was not recommended by Journal of the American Academy of Dermatology Advisory Statement. Indeed, the data on the risk of developing SSI after dermatologic surgery in immunosuppressed patients are limited. However, it is possible that due to the insufficient evidence on the risk of SSI occurrence in this patient group, dermatologic surgeons tend to overuse perioperative antibiotic prophylaxis. To make specific recommendations on the use of antibiotic prophylaxis in immunosuppressed patients in the field of skin surgery, more information about the incidence of SSI after dermatologic surgery in these patients is needed. The aim of this study was to fill this data gap by investigating whether there is an increased risk of SSI after skin surgery in immunocompromised patients compared with immunocompetent patients. Y1 - 2018 U6 - https://doi.org/10.1097/DSS.0000000000001615 IS - 44 (12) SP - 1525 EP - 1536 PB - Wolters Kluwer ER - TY - JOUR A1 - Rittweger, Jörn A1 - Albracht, Kirsten A1 - Flück, Martin A1 - Ruoss, Severin A1 - Brocca, Lorenza A1 - Longa, Emanuela A1 - Moriggi, Manuela A1 - Seynnes, Olivier A1 - Di Giulio, Irene A1 - Tenori, Leonardo A1 - Vignoli, Alessia A1 - Capri, Miriam A1 - Gelfi, Cecilia A1 - Luchinat, Claudio A1 - Franceschi, Claudio A1 - Bottinelli, Roberto A1 - Cerretelli, Paolo A1 - Narici, Marco T1 - Sarcolab pilot study into skeletal muscle’s adaptation to longterm spaceflight JF - npj Microgravity Y1 - 2018 U6 - https://doi.org/10.1038/s41526-018-0052-1 SN - 2373-8065 VL - 4 IS - 1 SP - 1 EP - 9 PB - Nature Portfolio ER - TY - JOUR A1 - Matcha, Heike A1 - Ljubas, Ante A1 - Gueldemet, Harun ED - Kepczynska-Walczak, A. T1 - Printing a Coffee Bar: An investigation into mid-scale 3D printing JF - Computing for a better tomorrow - Proceedings of the 36th eCAADe Conference - Volume 2, Lodz University of Technology, Lodz, Poland, 19-21 September 2018 N2 - We present and discuss an exploration of the possibilities and properties of 3D printing with a printing space of 1 cubic meter, and how those can be integrated into architectural education through an experimental design and research course with students of architecture.We expand on issues presented at the eCAADe conference 2017 in Rome [Ref 6] by increasing the complexity and size of our prints, printing not a model to scale, but a full scale funtional prototype of a usable architectural object: A coffee bar. Y1 - 2018 SP - 59 EP - 68 ER - TY - CHAP A1 - Bosse, Elke A1 - De Clercq, Mikael A1 - Barnat, Miriam T1 - The Role of Diversity for the Transition to Higher Education T2 - EARLI SIG 4, Giessen Y1 - 2018 ER - TY - JOUR A1 - Otten, Dennis A1 - Weber, Tobias A1 - Arent, Jan-Christoph T1 - Manufacturing Process Simulation – On Its Way to Industrial Application JF - International Journal of Aviation, Aeronautics, and Aerospace N2 - Manufacturing process simulation (MPS) has become more and more important for aviation and the automobile industry. A highly competitive market requires the use of high performance metals and composite materials in combination with reduced manufacturing cost and time as well as a minimization of the time to market for a new product. However, the use of such materials is expensive and requires sophisticated manufacturing processes. An experience based process and tooling design followed by a lengthy trial-and-error optimization is just not contemporary anymore. Instead, a tooling design process aided by simulation is used more often. This paper provides an overview of the capabilities of MPS in the fields of sheet metal forming and prepreg autoclave manufacturing of composite parts summarizing the resulting benefits for tooling design and manufacturing engineering. The simulation technology is explained briefly in order to show several simplification and optimization techniques for developing industrialized simulation approaches. Small case studies provide examples of an efficient application on an industrial scale. Y1 - 2018 U6 - https://doi.org/10.15394/ijaaa.2018.1217 SN - 2374-6793 VL - 5 IS - 2 PB - Embry-Riddle Aeronautical University CY - Daytona Beach, Fla. ER - TY - CHAP A1 - Jockwer, R. A1 - Kleiber, M. A1 - Uibel, Thomas ED - Görlacher, Rainer T1 - Criteria for Evaluating the Simplification of Design Rules for Dowel-type Fasteners T2 - International Network on Timber Engineering Research, INTER : proceedings, meeting 51, 10 - 13 August 2016, Tallinn, Estonia Y1 - 2018 SP - 461 EP - 466 PB - Timber Scientific Publishing, KIT Holzbau und Baukonstruktionen CY - Karlsruhe ER - TY - JOUR A1 - Svaneborg, Carsten A1 - Karimi-Varzaneh, Hossein Ali A1 - Hojdis, Nils A1 - Fleck, Franz A1 - Everaers, Ralf T1 - Kremer-Grest Models for Universal Properties of Specific Common Polymer Species JF - Soft Condensed Matter N2 - The Kremer-Grest (KG) bead-spring model is a near standard in Molecular Dynamic simulations of generic polymer properties. It owes its popularity to its computational efficiency, rather than its ability to represent specific polymer species and conditions. Here we investigate how to adapt the model to match the universal properties of a wide range of chemical polymers species. For this purpose we vary a single parameter originally introduced by Faller and Müller-Plathe, the chain stiffness. Examples include polystyrene, polyethylene, polypropylene, cis-polyisoprene, polydimethylsiloxane, polyethyleneoxide and styrene-butadiene rubber. We do this by matching the number of Kuhn segments per chain and the number of Kuhn segments per cubic Kuhn volume for the polymer species and for the Kremer-Grest model. We also derive mapping relations for converting KG model units back to physical units, in particular we obtain the entanglement time for the KG model as function of stiffness allowing for a time mapping. To test these relations, we generate large equilibrated well entangled polymer melts, and measure the entanglement moduli using a static primitive-path analysis of the entangled melt structure as well as by simulations of step-strain deformation of the model melts. The obtained moduli for our model polymer melts are in good agreement with the experimentally expected moduli. Y1 - 2018 IS - 1606.05008 ER - TY - JOUR A1 - Altherr, Lena A1 - Leise, Philipp A1 - Pfetsch, Marc E. A1 - Schmitt, Andreas T1 - Algorithmic design and resilience assessment of energy efficient high-rise water supply systems JF - Applied Mechanics and Materials N2 - High-rise water supply systems provide water flow and suitable pressure in all levels of tall buildings. To design such state-of-the-art systems, the consideration of energy efficiency and the anticipation of component failures are mandatory. In this paper, we use Mixed-Integer Nonlinear Programming to compute an optimal placement of pipes and pumps, as well as an optimal control strategy.Moreover, we consider the resilience of the system to pump failures. A resilient system is able to fulfill a predefined minimum functionality even though components fail or are restricted in their normal usage. We present models to measure and optimize the resilience. To demonstrate our approach, we design and analyze an optimal resilient decentralized water supply system inspired by a real-life hotel building. KW - MINLP KW - Buffering Capacity KW - Uncertainty KW - Water Supply Networks KW - Booster Stations Y1 - 2018 U6 - https://doi.org/10.4028/www.scientific.net/AMM.885.211 SN - 1662-7482 VL - 885 SP - 211 EP - 223 PB - Trans Tech Publications CY - Bäch ER - TY - JOUR A1 - de Blois, Eric A1 - de Zanger, Rory M. S. A1 - Paulßen, Elisabeth A1 - Sze Chan, Ho A1 - Breeman, Wouter A. P. T1 - Semi-automated system for concentrating 68Ga-eluate to obtain high molar and volume concentration of 68Ga-Radiopharmaca for preclinical applications JF - Nuclear Medicine and Biology N2 - 68Ga-radiopharmaceuticals are common in the field of Nuclear Medicine to visualize receptor-mediated processes. In contrast to straightforward labeling procedures for clinical applications, preclinical in vitro and in vivo applications are hampered for reasons like e.g. volume restriction, activity concentration, molar activity and osmolality. Therefore, we developed a semiautomatic system specifically to overcome these problems. A difficulty appeared unexpectedly, as intrinsic trace metals derived from eluate (Zn, Fe and Cu) are concentrated as well in amounts that influence radiochemical yield and thus lower molar activity. Y1 - 2018 U6 - https://doi.org/10.1016/j.nucmedbio.2018.06.006 VL - 64-65 SP - 16 EP - 21 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Schmidts, Oliver A1 - Kraft, Bodo A1 - Schreiber, Marc A1 - Zündorf, Albert T1 - Continuously evaluated research projects in collaborative decoupled environments T2 - 2018 ACM/IEEE 5th International Workshop on Software Engineering Research and Industrial PracticePractice, May 29, 2018, Gothenburg, Sweden : SER&IP' 18 N2 - Often, research results from collaboration projects are not transferred into productive environments even though approaches are proven to work in demonstration prototypes. These demonstration prototypes are usually too fragile and error-prone to be transferred easily into productive environments. A lot of additional work is required. Inspired by the idea of an incremental delivery process, we introduce an architecture pattern, which combines the approach of Metrics Driven Research Collaboration with microservices for the ease of integration. It enables keeping track of project goals over the course of the collaboration while every party may focus on their expert skills: researchers may focus on complex algorithms, practitioners may focus on their business goals. Through the simplified integration (intermediate) research results can be introduced into a productive environment which enables getting an early user feedback and allows for the early evaluation of different approaches. The practitioners’ business model benefits throughout the full project duration. Y1 - 2018 SP - 1 EP - 9 PB - ACM CY - New York, NY ER - TY - THES A1 - Keinz, Jan T1 - Optimization of a Dry Low NOx Micromix Combustor for an Industrial Gas Turbine Using Hydrogen-Rich Syngas Fuel Y1 - 2018 N1 - Dissertation submitted for the degree of Doctor of Engineering Sciences and Technology ; in Cooperation with Aachen university of Applied Sciences, Department Aerospace Technology; Thesis director: Prof. P. Hendrick; Thesis co-director: Prof. H. Funke PB - Université Libre de Bruxelles - Brussels School of Engineering Aero-Thermo-Mechanics CY - Brüssel ER - TY - CHAP A1 - Essingholt, Felix A1 - Meyer, Frederic A1 - Kuhn, Peter A1 - Schmidt, Philip A1 - Benkner, Thorsten A1 - Grabmaier, Anton T1 - Non-invasive heart beat measurement using microwave resonators T2 - Proceedings, Vol. 2, Eurosensors 2018 Conference, Graz, Austria, 9–12 September 2018 Y1 - 2018 U6 - https://doi.org/10.3390/proceedings2131002 SN - 2504-3900 SP - 1002 PB - MDPI CY - Basel ER - TY - CHAP A1 - Christian, Esser A1 - Montag, Tim A1 - Schuba, Marko A1 - Allhof, Manuel T1 - Future critical infrastructure and security - cyberattacks on charging stations T2 - 31st International Electric Vehicle Symposium & Exhibition and International Electric Vehicle Technology Conference (EVS31 & EVTeC 2018) Y1 - 2018 SN - 978-1-5108-9157-9 SP - 665 EP - 671 PB - Society of Automotive Engineers of Japan (JSAE) CY - Tokyo ER - TY - JOUR A1 - Ketelhut, Maike A1 - Göll, Fabian A1 - Braunstein, Björn A1 - Albracht, Kirsten A1 - Abel, Dirk T1 - Comparison of different training algorithms for the leg extension training with an industrial robot JF - Current Directions in Biomedical Engineering N2 - In the past, different training scenarios have been developed and implemented on robotic research platforms, but no systematic analysis and comparison have been done so far. This paper deals with the comparison of an isokinematic (motion with constant velocity) and an isotonic (motion against constant weight) training algorithm. Both algorithms are designed for a robotic research platform consisting of a 3D force plate and a high payload industrial robot, which allows leg extension training with arbitrary six-dimensional motion trajectories. In the isokinematic as well as the isotonic training algorithm, individual paths are defined i n C artesian s pace by sufficient s upport p oses. I n t he i sotonic t raining s cenario, the trajectory is adapted to the measured force as the robot should only move along the trajectory as long as the force applied by the user exceeds a minimum threshold. In the isotonic training scenario however, the robot’s acceleration is a function of the force applied by the user. To validate these findings, a simulative experiment with a simple linear trajectory is performed. For this purpose, the same force path is applied in both training scenarios. The results illustrate that the algorithms differ in the force dependent trajectory adaption. KW - Rehabilitation Technology and Prosthetics KW - Surgical Navigation and Robotics Y1 - 2018 U6 - https://doi.org/10.1515/cdbme-2018-0005 SN - 2364-5504 VL - 4 IS - 1 SP - 17 EP - 20 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Werkhausen, Amelie A1 - Albracht, Kirsten A1 - Cronin, Neil J A1 - Paulsen, Gøran A1 - Bojsen-Møller, Jens A1 - Seynnes, Olivier R T1 - Effect of training-induced changes in achilles tendon stiffness on muscle-tendon behavior during landing JF - Frontiers in physiology N2 - During rapid deceleration of the body, tendons buffer part of the elongation of the muscle-tendon unit (MTU), enabling safe energy dissipation via eccentric muscle contraction. Yet, the influence of changes in tendon stiffness within the physiological range upon these lengthening contractions is unknown. This study aimed to examine the effect of training-induced stiffening of the Achilles tendon on triceps surae muscle-tendon behavior during a landing task. Twenty-one male subjects were assigned to either a 10-week resistance-training program consisting of single-leg isometric plantarflexion (n = 11) or to a non-training control group (n = 10). Before and after the training period, plantarflexion force, peak Achilles tendon strain and stiffness were measured during isometric contractions, using a combination of dynamometry, ultrasound and kinematics data. Additionally, testing included a step-landing task, during which joint mechanics and lengths of gastrocnemius and soleus fascicles, Achilles tendon, and MTU were determined using synchronized ultrasound, kinematics and kinetics data collection. After training, plantarflexion strength and Achilles tendon stiffness increased (15 and 18%, respectively), and tendon strain during landing remained similar. Likewise, lengthening and negative work produced by the gastrocnemius MTU did not change detectably. However, in the training group, gastrocnemius fascicle length was offset (8%) to a longer length at touch down and, surprisingly, fascicle lengthening and velocity were reduced by 27 and 21%, respectively. These changes were not observed for soleus fascicles when accounting for variation in task execution between tests. These results indicate that a training-induced increase in tendon stiffness does not noticeably affect the buffering action of the tendon when the MTU is rapidly stretched. Reductions in gastrocnemius fascicle lengthening and lengthening velocity during landing occurred independently from tendon strain. Future studies are required to provide insight into the mechanisms underpinning these observations and their influence on energy dissipation. KW - achilles tendon KW - energy absorption KW - energy dissipation KW - mechanical buffer KW - stiffness Y1 - 2018 U6 - https://doi.org/10.3389/fphys.2018.00794 SN - 1664-042X IS - 9 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Funke, Harald A1 - Beckmann, Nils A1 - Keinz, Jan A1 - Abanteriba, Sylvester T1 - Comparison of Numerical Combustion Models for Hydrogen and Hydrogen-Rich Syngas Applied for Dry-Low-Nox-Micromix-Combustion JF - Journal of Engineering for Gas Turbines and Power N2 - The Dry-Low-NOx (DLN) Micromix combustion technology has been developed as low emission combustion principle for industrial gas turbines fueled with hydrogen or syngas. The combustion process is based on the phenomenon of jet-in-crossflow-mixing (JICF). Fuel is injected perpendicular into the air-cross-flow and burned in a multitude of miniaturized, diffusion-like flames. The miniaturization of the flames leads to a significant reduction of NOx emissions due to the very short residence time of reactants in the flame. In the Micromix research approach, computational fluid dynamics (CFD) analyses are validated toward experimental results. The combination of numerical and experimental methods allows an efficient design and optimization of DLN Micromix combustors concerning combustion stability and low NOx emissions. The paper presents a comparison of several numerical combustion models for hydrogen and hydrogen-rich syngas. They differ in the complexity of the underlying reaction mechanism and the associated computational effort. The performance of a hybrid eddy-break-up (EBU) model with a one-step global reaction is compared to a complex chemistry model and a flamelet generated manifolds (FGM) model, both using detailed reaction schemes for hydrogen or syngas combustion. Validation of numerical results is based on exhaust gas compositions available from experimental investigation on DLN Micromix combustors. The conducted evaluation confirms that the applied detailed combustion mechanisms are able to predict the general physics of the DLN-Micromix combustion process accurately. The FGM method proved to be generally suitable to reduce the computational effort while maintaining the accuracy of detailed chemistry. Y1 - 2018 U6 - https://doi.org/10.1115/1.4038882 SN - 0742-4795 N1 - Article number 081504; Paper No: GTP-17-1567 VL - 140 IS - 8 PB - ASME CY - New York, NY ER - TY - CHAP A1 - Rosin, Julia A1 - Butenweg, Christoph A1 - Boesen, Niklas A1 - Gellert, Christoph T1 - Evaluation of the Seismic Behavior of a Modern URM Building During the 2012 Northern Italy Earthquakes T2 - 16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018 Y1 - 2018 SP - 1 EP - 12 ER - TY - CHAP A1 - Grundmann, Jan Thimo A1 - Bauer, Waldemar A1 - Borchers, Kai A1 - Dumont, Etienne A1 - Grimm, Christian D. A1 - Ho, Tra-Mi A1 - Jahnke, Rico A1 - Lange, Caroline A1 - Maiwald, Volker A1 - Mikulz, Eugen A1 - Quantius, Dominik A1 - Reershemius, Siebo A1 - Renger, Thomas A1 - Riemann, Johannes A1 - Sasaki, Kaname A1 - Seefeldt, Patric A1 - Spietz, Peter A1 - Spröwitz, Tom A1 - Toth, Norbert A1 - Wejmo, Elisabet A1 - Biele, Jens A1 - Krause, Christian A1 - Cerotti, Matteo A1 - Peloni, Alessandro A1 - Dachwald, Bernd T1 - Small Spacecraft Solar Sailing for Small Solar System Body Multiple Rendezvous and Landing T2 - 2018 IEEE Aerospace Conference : 3-10 March 2018 Y1 - 2018 SN - 978-1-5386-2014-4 ER - TY - CHAP A1 - Schmitt, Timo A1 - Rosin, Julia A1 - Butenweg, Christoph T1 - Seismic Impact And Design Of Buried Pipelines T2 - 16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018 N2 - Seismic design of buried pipeline systems for energy and water supply is not only important for plant and operational safety but also for the maintenance of the supply infrastructure after an earthquake. The present paper shows special issues of the seismic wave impacts on buried pipelines, describes calculation methods, proposes approaches and gives calculation examples. This paper regards the effects of transient displacement differences and resulting tensions within the pipeline due to the wave propagation of the earthquake. However, the presented model can also be used to calculate fault rupture induced displacements. Based on a three-dimensional Finite Element Model parameter studies are performed to show the influence of several parameters such as incoming wave angle, wave velocity, backfill height and synthetic displacement time histories. The interaction between the pipeline and the surrounding soil is modeled with non-linear soil springs and the propagating wave is simulated affecting the pipeline punctually, independently in time and space. Special attention is given to long-distance heat pipeline systems. Here, in regular distances expansion bends are arranged to ensure movements of the pipeline due to high temperature. Such expansion bends are usually designed with small bending radii, which during the earthquake lead to high bending stresses in the cross-section of the pipeline. Finally, an interpretation of the results and recommendations are given for the most critical parameters. Y1 - 2018 N1 - Paper No 10600 SP - 1 EP - 12 ER - TY - CHAP A1 - Butenweg, Christoph A1 - Marinkovic, Marko A1 - Fehling, Ekkehard A1 - Pfetzing, Thomas A1 - Kubalski, Thomas T1 - Experimental and Numerical Investigations of Reinforced Concrete Frames with Masonry Infills under Combined In- and Out-of-plane Seismic Loading T2 - 16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018 Y1 - 2018 N1 - Paper No 11477 SP - 1 EP - 12 ER - TY - CHAP A1 - Milkova, Kristina A1 - Rosin, Julia A1 - Butenweg, Christoph A1 - Dumova-Jovanoska, Elena T1 - Development of Seismic Vulnerability Curves for Region Specific Masonry Buildings T2 - 16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018 Y1 - 2018 N1 - Paper No 10522 SP - 1 EP - 10 ER - TY - CHAP A1 - Michel, Philipp A1 - Butenweg, Christoph A1 - Klinkel, Sven T1 - Frequency Dependent Impedance Analysis of the Foundation-Soil-Systems of Onshore Wind Turbines T2 - 16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018 Y1 - 2018 N1 - Paper No 11440 SP - 1 EP - 13 ER - TY - CHAP A1 - Butenweg, Christoph A1 - Marinkovic, Marko T1 - Damage reduction system for masonry infill walls under seismic loading T2 - ce/papers N2 - Reinforced concrete (RC) frames with masonry infills are frequently used in seismic regions all over the world. Generally masonry infills are considered as nonstructural elements and thus are typically neglected in the design process. However, the observations made after strong earthquakes have shown that masonry infills can modify the dynamic behavior of the structure significantly. The consequences were total collapses of buildings and loss of human lives. This paper presents the new system INODIS (Innovative Decoupled Infill System) developed within the European research project INSYSME (Innovative Systems for Earthquake Resistant Masonry Enclosures in RC Buildings). INODIS decouples the frame and the masonry infill by means of special U-shaped rubbers placed in between frame and infill. The effectiveness of the system was investigated by means of full scale tests on RC frames with masonry infills subjected to in-plane and out-of-plane loading. Furthermore small specimen tests were conducted to determine material characteristics of the components and the resistances of the connections. Finally, a micromodel was developed to simulate the in-plane behavior of RC frames infilled with AAC blocks with and without installation of the INODIS system. KW - earthquakes KW - in-plane and out-of-plane failure KW - INODIS KW - RC frames Y1 - 2018 U6 - https://doi.org/10.1002/cepa.863 N1 - Special Issue: ICAAC ‐ 6th International Conference on Autoclaved Aerated Concrete VL - 2 IS - 4 SP - 267 EP - 273 PB - Ernst & Sohn Verlag CY - Berlin ER - TY - CHAP A1 - Marinkovic, Marko A1 - Butenweg, Christoph T1 - Innovative System for Earthquake Resistant Masonry Infill Walls T2 - 16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018 Y1 - 2018 N1 - Paper No 11479 SP - 1 EP - 12 ER - TY - CHAP A1 - Grundmann, Jan Thimo A1 - Bauer, Waldemar A1 - Biele, Jens A1 - Boden, Ralf A1 - Ceriotti, Matteo A1 - Cordero, Federico A1 - Dachwald, Bernd A1 - Dumont, Etienne A1 - Grimm, Christian A1 - Herčík, David A1 - Herique, Alain A1 - Ho, Tra-Mi A1 - Jahnke, Rico A1 - Koch, Aaron A1 - Kofman, Wlodek A1 - Koncz, Alexander A1 - Krause, Christian A1 - Lange, Caroline A1 - Lichtenheldt, Roy A1 - Maiwald, Volker A1 - Mikschl, Tobias A1 - Mikulz, Eugen A1 - Montenegro, Sergio A1 - Pelivan, Ivanka A1 - Peloni, Alessandro A1 - Plettemeier, Dirk A1 - Quantius, Dominik A1 - Reershemius, Siebo A1 - Renger, Thomas A1 - Riemann, Johannes A1 - Ruffer, Michael A1 - Sasaki, Kaname A1 - Schmitz, Nicole A1 - Seboldt, Wolfgang A1 - Seefeldt, Patric A1 - Spietz, Peter A1 - Spröwitz, Tom A1 - Sznajder, Maciej A1 - Tardivel, Simon A1 - Toth, Norbert A1 - Wejmo, Elisabet A1 - Wolff, Friederike A1 - Ziach, Christian T1 - Efficient massively parallel prospection for ISRU by multiple near-earth asteroid rendezvous using near-term solar sails and'now-term'small spacecraft solutions T2 - 2nd Asteroid Science Intersections with In-Space Mine Engineering – ASIME 2018 N2 - Physical interaction with small solar system bodies (SSSB) is key for in-situ resource utilization (ISRU). The design of mining missions requires good understanding of SSSB properties, including composition, surface and interior structure, and thermal environment. But as the saying goes "If you've seen one asteroid, you've seen one Asteroid": Although some patterns may begin to appear, a stable and reliable scheme of SSSB classification still has to be evolved. Identified commonalities would enable generic ISRU technology and spacecraft design approaches with a high degree of re-use. Strategic approaches require much broader in-depth characterization of the SSSB populations of interest to the ISRU community. The DLR-ESTEC GOSSAMER Roadmap Science Working Groups identified target-flexible Multiple Near-Earth asteroid (NEA) Rendezvous (MNR) as one of the missions only feasible with solar sail propulsion, showed the ability to access any inclination and a wide range of heliocentric distances as well as continuous operation close to Earth's orbit where low delta-v objects reside. Y1 - 2018 N1 - 2nd Asteroid Science Intersections with In-Space Mine Engineering – ASIME 2018 16-17 April 2018, Belval, Luxembourg SP - 1 EP - 33 ER - TY - CHAP A1 - König, Johannes Alexander A1 - Wolf, Martin R. T1 - Cybersecurity awareness training provided by the competence developing game GHOST T2 - ACHI 2018 : The Eleventh International Conference on Advances in Computer-Human Interactions N2 - This paper introduces a Competence Developing Game (CDG) for the purpose of a cybersecurity awareness training for businesses. The target audience will be discussed in detail to understand their requirements. It will be explained why and how a mix of business simulation and serious game meets these stakeholder requirements. It will be shown that a tablet and touchscreen based approach is the most suitable solution. In addition, an empirical study will be briefly presented. The study was carried out to examine how an interaction system for a 3D-tablet based CDG has to be designed, to be manageable for non-game experienced employees. Furthermore, it will be explained which serious content is necessary for a Cybersecurity awareness training CDG and how this content is wrapped in the game KW - Awareness KW - CDG KW - Serious Game KW - tablet game KW - business simulation Y1 - 2018 SN - 978-1-61208-616-3 N1 - Proceeding of the Eleventh International Conference on Advances in Computer-Human Interactions (ACHI 2018), Rome, Italy. SP - 81 EP - 87 ER -