TY  - JOUR
A1  - Baroud, G.
A1  - Wu, J.Z.
A1  - Bohner, M
A1  - Sponagel, Stefan
A1  - Steffen, T.
T1  - How to determine the permeability for cement infiltration into osteoporotic cancellous bone
JF  - Medical Engineering & Physics. 25 (2003), H. 4
N2  - Cement augmentation is an emerging surgical procedure in which bone cement is used to infiltrate and reinforce osteoporotic vertebrae. Although this infiltration procedure has been widely applied, it is performed empirically and little is known about the flow characteristics of cement during the injection process. We present a theoretical and experimental approach to investigate the intertrabecular bone permeability during the infiltration procedure. The cement permeability was considered to be dependent on time, bone porosity, and cement viscosity in our analysis. In order to determine the time-dependent permeability, ten cancellous bone cores were harvested from osteoporotic vertebrae, infiltrated with acrylic cement at a constant flow rate, and the pressure drop across the cores during the infiltration was measured. The viscosity dependence of the permeability was determined based on published experimental data. The theoretical model for the permeability as a function of bone porosity and time was then fit to the testing data. Our findings suggest that the intertrabecular bone permeability depends strongly on time. For instance, the initial permeability (60.89 mm4/N.s) reduced to approximately 63% of its original value within 18 seconds. This study is the first to analyze cement flow through osteoporotic bone. The theoretical and experimental models provided in this paper are generic. Thus, they can be used to systematically study and optimize the infiltration process for clinical practice.
KW  - Osteoporose
KW  - Permeabilität
KW  - Viskose Strömung
KW  - Viskosität
KW  - Vertebroplastie
KW  - Cement infiltration
KW  - Vertebroplasty
KW  - Osteoporosis
KW  - Permeability
KW  - Experiment
KW  - Analysis
KW  - Viscous flow
Y1  - 2003
SN  - 1350-4533
SP  - 283
EP  - 288
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Burns, Laura
A1  - Canaves, Jaume M.
A1  - Temiz Artmann, Aysegül
T1  - Circular dichroism spectra of human hemoglobin reveal a reversible structural transition at body temperature
JF  - European Biophysics Journal. 33 (2004), H. 6
Y1  - 2004
SN  - 1432-1017
SP  - 490
EP  - 496
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Trzewik, Jürgen
A1  - Ates, M.
T1  - A novel method to quantify mechanical tension in cell monolayers. Trzewik, Jürgen; Ates, M., Artmann, Gerhard Michael
JF  - Biomedizinische Technik. 47 (2002), H. Suppl. 1. Pt. 1
Y1  - 2002
SN  - 0013-5585
N1  - Druckausgabe unter 63 Z 47 vorhanden
SP  - 379
EP  - 381
ER  - 
TY  - JOUR
A1  - Maggakis-Kelemen, Christina
A1  - Biselli, Manfred
A1  - Artmann, Gerhard
T1  - Determination of the elastic shear modulus of cultured human red blood cells
JF  - Biomedizinische Technik. 47 (2002), H. Suppl. 1 Pt. 1
Y1  - 2002
SN  - 0013-5585
N1  - Druckausgabe unter 63 Z 471 vorhanden
SP  - 106
EP  - 109
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Zhou-Stache, J.
A1  - Buettner, R.
A1  - Mittermayer, C. [u.a.]
T1  - Inhibition of TNF-alpha induced cell death in HUVEC and Jurkat cells by protocatechuic acid. Zhou-Stache, J.; Buettner, R.; Artmann, Gerhard Michael; Mittermayer, C.; Bosserhoff, A. K.
JF  - Medical and Biological Engineering and Computing. 40 (2002), H. 6
Y1  - 2002
SN  - 0140-0118
SP  - 698
EP  - 703
ER  - 
TY  - JOUR
A1  - Sponagel, Stefan
A1  - Baroud, G.
A1  - Steffen, T.
A1  - Wu, J.
T1  - Parameter identification for cement infiltration of osteoporotic bone
JF  - Poromechanics II : Proceedings of the Second Biot Conference on Poromechanics Grenoble, France 26 - 28 August 2002 / ed. by J.-L. Auriault ...
Y1  - 2002
SN  - 90-5809-394-8
SP  - 55
EP  - 58
PB  - Balkema
CY  - Lisse [u.a.]
ER  - 
TY  - JOUR
A1  - Sponagel, Stefan
A1  - Unger, J.
A1  - Spies, K. H.
T1  - Härtebegriff im Zusammenhang mit Vernetzung, Bruchdehnung und Dauerfestigkeit eines Elastomers
JF  - Kautschuk Gummi Kunststoffe. 56 (2003), H. 11
Y1  - 2003
SN  - 0948-3276
SP  - 608
EP  - 613
ER  - 
TY  - JOUR
A1  - Sponagel, Stefan
A1  - Baroud, G.
A1  - Falk, R.
A1  - Crookshank, M.
T1  - Experimental and theoretical investigation of directional permeability of human vertebral cancellous bone for cement infiltration. G. Baroud, R. Falk, M. Crookshank, S. Sponagel, T. Steffen
JF  - Journal of Biomechanics. 37 (2004), H. 2
Y1  - 2004
SN  - 0021-9290
SP  - 189
EP  - 196
ER  - 
TY  - JOUR
A1  - Sponagel, Stefan
A1  - Baroud, G.
A1  - Falk, R.
A1  - Crookshank, M.
T1  - Corrigendum to “Experimental and theoretical investigation of directional permeability of human vertebral cancellous bone for cement infiltration”. Baroud, G.; Falk, R.; Crookshank, M.; Sponagel, S.; Steffen, T.
JF  - Journal of Biomechanics. 37 (2004), H. 2
Y1  - 2004
SN  - 0021-9290
SP  - 1802
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Hueck, Isgard S.
A1  - Rossiter, Katharine
A1  - Schmid-Schönbein, Geert W.
T1  - Fluid Shear Attenuates Endothelial Pseudopodia Formation into the Capillary Lumen / Hueck, Isgard S. ; Rossiter, Katharine ; Artman, Gerhard M. ; Schmid-Schönbein, Geert W.
JF  - Microcirculation. 15 (2008), H. 6
Y1  - 2008
SN  - 1549-8719
SP  - 531
EP  - 542
ER  -