TY  - CHAP
A1  - Tippkötter, Nils
A1  - Möhring, Sophie
A1  - Roth, Jasmine
A1  - Wulfhorst, Helene
T1  - Logistics of lignocellulosic feedstocks: preprocessing as a preferable option
T2  - Biorefineries
N2  - In comparison to crude oil, biorefinery raw materials are challenging in concerns of transport and storage. The plant raw materials are more voluminous, so that shredding and compacting usually are necessary before transport. These mechanical processes can have a negative influence on the subsequent biotechnological processing and shelf life of the raw materials. Various approaches and their effects on renewable raw materials are shown. In addition, aspects of decentralized pretreatment steps are discussed. Another important aspect of pretreatment is the varying composition of the raw materials depending on the growth conditions. This problem can be solved with advanced on-site spectrometric analysis of the material.
KW  - Analytics
KW  - Decentral
KW  - Mechanical
KW  - On-site
KW  - Pre-treatment
Y1  - 2019
SN  - 978-3-319-97117-9
SN  - 978-3-319-97119-3
U6  - https://doi.org/10.1007/10_2017_58
N1  - Advances in biochemical engineering/biotechnology ; Vol. 166
SP  - 43
EP  - 68
PB  - Springer
CY  - Cham
ER  - 
TY  - CHAP
A1  - Kazuki, Yasuhiro
A1  - Kobayashi, Kaoru
A1  - Hirabayashi, Masumi
A1  - Abe, Satoshi
A1  - Kajitani, Naoyo
A1  - Kazuki, Kanoko
A1  - Takehara, Shoko
A1  - Takiguchi, Masato
A1  - Satoh, Daisuke
A1  - Kuze, Jiro
A1  - Sakuma, Tetsushi
A1  - Kaneko, Takehito
A1  - Mashimo, Tomoji
A1  - Osamura, Minori
A1  - Hashimoto, Mari
A1  - Wakatsuki, Riko
A1  - Hirashima, Rika
A1  - Fujiwara, Ryoichi
A1  - Deguchi, Tsuneo
A1  - Kurihara, Atsushi
A1  - Tsukazaki, Yasuko
A1  - Senda, Naoto
A1  - Yamamoto, Takashi
A1  - Scheer, Nico
A1  - Oshimura, Mitsuo
T1  - Humanized UGT2 and CYP3A transchromosomic rats for improved prediction of human drug metabolism
T2  - PNAS Proceedings of the National Academy of Sciences of the United States of America
Y1  - 2019
U6  - https://doi.org/10.1073/pnas.1808255116
SN  - 1091-6490
VL  - 116
IS  - 8
SP  - 3072
EP  - 3081
ER  - 
TY  - JOUR
A1  - Leschinger, Tim
A1  - Birgel, Stefan
A1  - Hackl, Michael
A1  - Staat, Manfred
A1  - Müller, Lars Peter
A1  - Wegmann, Kilian
T1  - A musculoskeletal shoulder simulation of moment arms and joint reaction forces after medialization of the supraspinatus footprint in rotator cuff repair
JF  - Computer Methods in Biomechanics and Biomedical Engineering
Y1  - 2019
U6  - https://doi.org/10.1080/10255842.2019.1572749
IS  - Early view
PB  - Taylor & Francis
CY  - London
ER  - 
TY  - CHAP
A1  - Mataré, Victor
A1  - Schiffer, Stefan
A1  - Ferrein, Alexander
ED  - Steinbauer, Gerald
ED  - Ferrein, Alexander
T1  - golog++ : An integrative system design
T2  - CogRob 2018. Cognitive Robotics Workshop : Proceedings of the 11th Cognitive Robotics Workshop 2018 co-located with 16th International Conference on Principles of Knowledge Representation and Reasoning (KR 2018) Tempe, AZ, USA, October 27th, 2018
Y1  - 2019
SN  - 1613-0073
SP  - 29
EP  - 35
ER  - 
TY  - JOUR
A1  - Lyons, W. Berry
A1  - Mikucki, Jill A.
A1  - German, Laura A.
A1  - Welch, Kathleen A.
A1  - Welch, Susan A.
A1  - Gardener, Christopher B.
A1  - Tulaczyk, Slawek M.
A1  - Pettit, Erin C.
A1  - Kowalski, Julia
A1  - Dachwald, Bernd
T1  - The Geochemistry of Englacial Brine from Taylor Glacier, Antarctica
JF  - Journal of Geophysical Research: Biogeosciences
Y1  - 2019
U6  - https://doi.org/10.1029/2018JG004411
SN  - 2169-8961
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Campen, R.
A1  - Kowalski, Julia
A1  - Lyons, W.B.
A1  - Tulaczyk, S.
A1  - Dachwald, Bernd
A1  - Pettit, E.
A1  - Welch, K. A.
A1  - Mikucki, J.A.
T1  - Microbial diversity of an Antarctic subglacial community and high‐resolution replicate sampling inform hydrological connectivity in a polar desert
JF  - Environmental Microbiology
Y1  - 2019
U6  - https://doi.org/10.1111/1462-2920.14607
SN  - 1462-2920
IS  - accepted article
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Vögele, Stefan
A1  - Rübbelke, Dirk
A1  - Govorukha, Kristina
A1  - Grajewski, Matthias
T1  - Socio-technical scenarios for energy-intensive industries: the future of steel production in Germany
JF  - Climatic Change
Y1  - 2019
U6  - https://doi.org/10.1007/s10584-019-02366-0
SN  - 0165-0009
SP  - 1
EP  - 16
PB  - Springer
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Eggert, Mathias
T1  - Big Data Research - How to Structure the Changes of the Past Decade?
T2  - The Art of Structuring
N2  - In the past decade, many IS researchers focused on researching the phenomenon of Big Data. At the same time, the relevance of data protection gets more attention than ever before. In particular, since the enactment of the European General Data Protection Regulation in May 2018 Information Systems research should provide answers for protecting personal data. The article at hand presents a structuring framework for Big Data research outcome and the consideration of data protection. IS Researchers might use the framework in order to structure Big Data literature and to identify research gaps that should be addressed in the future.
Y1  - 2019
SN  - 978-3-030-06234-7
U6  - https://doi.org/10.1007/978-3-030-06234-7_26
SP  - 271
EP  - 281
PB  - Springer
CY  - Cham
ER  - 
TY  - CHAP
A1  - Dachwald, Bernd
A1  - Ohndorf, Andreas
T1  - Global optimization of continuous-thrust trajectories using evolutionary neurocontrol
T2  - Modeling and Optimization in Space Engineering
N2  - Searching optimal continuous-thrust trajectories is usually a difficult and time-consuming task. The solution quality of traditional optimal-control methods depends strongly on an adequate initial guess because the solution is typically close to the initial guess, which may be far from the (unknown) global optimum. Evolutionary neurocontrol attacks continuous-thrust optimization problems from the perspective of artificial intelligence and machine learning, combining artificial neural networks and evolutionary algorithms. This chapter describes the method and shows some example results for single- and multi-phase continuous-thrust trajectory optimization problems to assess its performance. Evolutionary neurocontrol can explore the trajectory search space more exhaustively than a human expert can do with traditional optimal-control methods. Especially for difficult problems, it usually finds solutions that are closer to the global optimum. Another fundamental advantage is that continuous-thrust trajectories can be optimized without an initial guess and without expert supervision.
Y1  - 2019
SN  - 978-3-030-10501-3
SN  - 978-3-030-10500-6
U6  - https://doi.org/10.1007/978-3-030-10501-3_2
N1  - Springer Optimization and Its Applications, vol 144
gedruckt unter der Signatur 21 ZSS 46 in der Bereichsbibliothek Eupener Str. vorhanden
SP  - 33
EP  - 57
PB  - Springer
CY  - Cham
ER  - 
TY  - CHAP
A1  - Schmidts, Oliver
A1  - Kraft, Bodo
A1  - Siebigteroth, Ines
A1  - Zündorf, Albert
T1  - Schema Matching with Frequent Changes on Semi-Structured Input Files: A Machine Learning Approach on Biological Product Data
T2  - Proceedings of the 21st International Conference on Enterprise Information Systems - Volume 1: ICEIS
Y1  - 2019
SN  - 978-989-758-372-8
U6  - https://doi.org/10.5220/0007723602080215
SP  - 208
EP  - 215
ER  - 
TY  - JOUR
A1  - Kapelyukh, Yury
A1  - Henderson, Colin James
A1  - Scheer, Nico
A1  - Rode, Anja
A1  - Wolf, Charles Roland
T1  - Defining the contribution of CYP1A1 and CYP1A2 to drug metabolism using humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 KO mice
JF  - Drug Metabolism and Disposition
Y1  - 2019
U6  - https://doi.org/10.1124/dmd.119.087718
IS  - Early view
ER  - 
TY  - BOOK
A1  - Wagemann, Kurt
A1  - Tippkötter, Nils
T1  - Biorefineries / Kurt Wagemann, Nils Tippkötter (editors)
T3  - Advances in biochemical engineering/biotechnology book series (ABE)
Y1  - 2019
SN  - 978-3-319-97117-9
SN  - 978-3-319-97119-3
U6  - https://doi.org/10.1007/978-3-319-97119-3
PB  - Springer
CY  - Cham (Switzerland)
ER  - 
TY  - JOUR
A1  - Morais, Paulo V.
A1  - Silva, Anielle C. A.
A1  - Dantas, Noelio O.
A1  - Schöning, Michael Josef
A1  - Siqueira, José R., Jr.
T1  - Hybrid Layer‐by‐Layer Film of Polyelectrolytes‐Embedded Catalytic CoFe2O4 Nanocrystals as Sensing Units in Capacitive Electrolyte‐Insulator‐Semiconductor Devices
JF  - physica status solidi a : applications and materials sciences
Y1  - 2019
U6  - https://doi.org/10.1002/pssa.201900044
VL  - 216
IS  - 1900044
SP  - 1
EP  - 9
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Rietsch, Stefan H. G.
A1  - Brunheim, Sascha
A1  - Orzada, Stephan
A1  - Voelker, Maximilian N.
A1  - Maderwald, Stefan
A1  - Bitz, Andreas
A1  - Gratz, Marcel
A1  - Ladd, Mark E.
A1  - Quick, Harald H.
T1  - Development and evaluation of a 16-channel receive-only RF coil to improve 7T ultra-high field body MRI with focus on the spine
JF  - Magnetic Resonance in Medicine
Y1  - 2019
U6  - https://doi.org/10.1002/mrm.27731
SN  - 1522-2594
IS  - Early view
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Albanna, Walid
A1  - Lüke, Jan Niklas
A1  - Schubert, Gerrit Alexander
A1  - Dibué-Adjei, Maxine
A1  - Kotliar, Konstantin
A1  - Hescheler, Jürgen
A1  - Clusmann, Hans
A1  - Steiger, Hans-Jakob
A1  - Hänggi, Daniel
A1  - Kamp, Marcel A.
A1  - Schneider, Toni
A1  - Neumaier, Felix
T1  - Modulation of Ca v 2.3 channels by unconjugated bilirubin (UCB) – Candidate mechanism for UCB-induced neuromodulation and neurotoxicity
JF  - Molecular and Cellular Neuroscience
Y1  - 2019
U6  - https://doi.org/10.1016/j.mcn.2019.03.003
SN  - 1044-7431
VL  - 96
IS  - 4
SP  - 35
EP  - 46
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Meyer, Carolin
A1  - Gaalen, Kerstin van
A1  - Leschinger, Tim
A1  - Scheyerer, Max J.
A1  - Neiss, Wolfram F.
A1  - Staat, Manfred
A1  - Müller, Lars P.
A1  - Wegmann, Kilian
T1  - Kyphoplasty of Osteoporotic Fractured Vertebrae: A Finite Element Analysis about Two Types of Cement
JF  - BioMed Research International
Y1  - 2019
U6  - https://doi.org/10.1155/2019/9232813
SP  - Article ID 9232813
ER  - 
TY  - JOUR
A1  - Jan Thimo, Grundmann
A1  - Bauer, Waldemar
A1  - Biele, Jens
A1  - Boden, Ralf
A1  - Ceriotti, Matteo
A1  - Cordero, Federico
A1  - Dachwald, Bernd
A1  - Dumont, Etienne
A1  - Grimm, Christian D.
A1  - Hercik, David
T1  - Capabilities of Gossamer-1 derived small spacecraft solar sails carrying Mascot-derived nanolanders for in-situ surveying of NEAs
JF  - Acta Astronautica
Y1  - 2019
U6  - https://doi.org/10.1016/j.actaastro.2018.03.019
SN  - 0094-5765
VL  - 156
IS  - 3
SP  - 330
EP  - 362
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Scheer, Nico
A1  - Henderson, Colin James
A1  - Kapelyukh, Yury
A1  - Rode, Anja
A1  - Mclaren, Aileen W.
A1  - MacLeod, Alastair Kenneth
A1  - Lin, De
A1  - Wright, Jayne
A1  - Stanley, Lesley
A1  - Wolf, C. Roland
T1  - An extensively humanised mouse model to predict pathways of drug disposition, drug/drug interactions, and to facilitate the design of clinical trials
JF  - Drug Metabolism and Disposition
Y1  - 2019
U6  - https://doi.org/10.1124/dmd.119.086397
IS  - Early view
ER  - 
TY  - JOUR
A1  - Jung, Alexander
A1  - Müller, Wolfram
A1  - Staat, Manfred
T1  - Optimization of the flight technique in ski jumping: the influence of wind
Y1  - 2019
U6  - https://doi.org/10.1016/j.jbiomech.2019.03.023
IS  - Early view
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Breuer, Lars
A1  - Pilas, Johanna
A1  - Guthmann, Eric
A1  - Schöning, Michael Josef
A1  - Thoelen, Ronald
A1  - Wagner, Torsten
T1  - Towards light-addressable flow control: responsive hydrogels with incorporated graphene oxide as laser-driven actuator structures within microfluidic channels
JF  - Sensor and Actuators B: Chemical
Y1  - 2019
U6  - https://doi.org/10.1016/j.snb.2019.02.086
SN  - 0925-4005
VL  - 288
SP  - 579
EP  - 585
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Funke, Harald
A1  - Beckmann, Nils
A1  - Abanteriba, Sylvester
T1  - An overview on dry low NOx micromix combustor development for hydrogen-rich gas turbine applications
JF  - International Journal of Hydrogen Energy
Y1  - 2019
U6  - https://doi.org/10.1016/j.ijhydene.2019.01.161
SN  - 0360-3199
VL  - 44
IS  - 13
SP  - 6978
EP  - 6990
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Franzen, Julian
A1  - Stecken, Jannis
A1  - Pfaff, Raphael
A1  - Kuhlenkötter, Bernd
T1  - Using the Digital Shadow for a Prescriptive Optimization of Maintenance and Operation : The Locomotive in the Context of the Cyber-Physical System
T2  - Advances in Production, Logistics and Traffic
N2  - In competition with other modes of transport, rail freight transport is looking for solutions to become more attractive. Short-term success can be achieved through the data-driven optimization of operations and maintenance as well as the application of novel strategies such as prescriptive maintenance. After introducing the concept of prescriptive maintenance, this paper aims to prove that vehicle-focused applications of this approach indeed have the potential to increase attractiveness. However, even greater advantages can be activated if data from the horizontal network of the vehicle is available. Drawing on the state of the art in research and technology in the field of cyber-physical systems (CPS) as well as digital twins and shadows, our work serves to design a system of systems for the horizontal interconnection of a rail vehicle and to conceptualize a draft for a digital twin of a locomotive.
Y1  - 2019
SN  - 978-3-030-13535-5
U6  - https://doi.org/10.1007/978-3-030-13535-5_19
SP  - 265
EP  - 276
PB  - Springer
CY  - Cham
ER  - 
TY  - JOUR
A1  - Cornelis, Peter
A1  - Givanoudi, Stella
A1  - Yongabi, Derick
A1  - Iken, Heiko
A1  - Duwé, Sam
A1  - Deschaume, Olivier
A1  - Robbens, Johan
A1  - Dedecker, Peter
A1  - Bartic, Carmen
A1  - Wübbenhorst, Michael
A1  - Schöning, Michael Josef
A1  - Heyndrickx, Marc
A1  - Wagner, Patrick
T1  - Sensitive and specific detection of E. coli using biomimetic receptors in combination with a modified heat-transfer method
JF  - Biosensors and Bioelectronics
Y1  - 2019
U6  - https://doi.org/10.1016/j.bios.2019.04.026
SN  - 0956-5663
VL  - 136
SP  - 97
EP  - 105
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Geissler, Hanno
A1  - Schöning, Michael Josef
T1  - Rapid methods and sensors for milk quality monitoring and spoilage detection
JF  - Biosensors and Bioelectronics
Y1  - 2019
U6  - https://doi.org/10.1016/j.bios.2019.04.040
SN  - 0956-5663
VL  - 140
IS  - Article 111272
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - BOOK
A1  - Meskouris, Konstantin
A1  - Butenweg, Christoph
A1  - Hinzen, Klaus-G.
A1  - Höffer, Rüdiger
T1  - Structural Dynamics with Applications in Earthquake and Wind Engineering
Y1  - 2019
SN  - 978-3-662-57550-5
U6  - https://doi.org/10.1007/978-3-662-57550-5
PB  - Springer
CY  - Berlin, Heidelberg
ER  - 
TY  - CHAP
A1  - Meskouris, Konstantin
A1  - Butenweg, Christoph
A1  - Hinzen, Klaus-G.
A1  - Höffer, Rüdiger
T1  - Stochasticity of Wind Processes and Spectral Analysis of Structural Gust Response
T2  - Structural Dynamics with Applications in Earthquake and Wind Engineering
N2  - Wind loads have great impact on many engineering structures. Wind storms often cause irreparable damage to the buildings which are exposed to it. Along with the earthquakes, wind represents one of the most common environmental load on structures and is relevant for limit state design. Modern wind codes indicate calculation procedures allowing engineers to deal with structural systems, which are susceptible to conduct wind-excited oscillations. In the codes approximate formulas for wind buffeting are specified which relate the dynamic problem to rather abstract parameter functions. The complete theory behind is not visible in order to simplify the applicability of the procedures. This chapter derives the underlying basic relations of the spectral method for wind buffeting and explains the main important applications of it in order to elucidate part of the theoretical background of computations after the new codes. The stochasticity of the wind processes is addressed, and the analysis of analytical as well as measurement based power spectra is outlined. Short MATLAB codes are added to the Appendix 3 which carry out the computation of a single sided auto-spectrum from a statistically stationary, discrete stochastic process. Two examples are presented.
KW  - Wind turbulence
KW  - Gust wind response
KW  - Spectral analysis
Y1  - 2019
SN  - 978-3-662-57550-5 (Online)
SN  - 978-3-662-57548-2 (Print)
U6  - https://doi.org/10.1007/978-3-662-57550-5_3
SP  - 153
EP  - 196
PB  - Springer
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Bung, Daniel Bernhard
A1  - Oertel, Mario
T1  - Wave breaking over a submerged horizontal plate: Optical Flow, LES and RANS
T2  - E-proceedings of the 38th IAHR World Congress  September 1-6, 2019, Panama City, Panama
Y1  - 2019
U6  - https://doi.org/10.3850/38WC092019-0509
SP  - 3690
EP  - 3698
ER  - 
TY  - CHAP
A1  - Braun, Sebastian
A1  - Cheng, Chi-Tsun
A1  - Lai, Chow Yin
A1  - Wollert, Jörg
T1  - Microservice Architecture for Automation - Realization by the example of a model-factory’s manufacturing execution system
T2  - Proceedings of the 23rd World Multi-Conference on Systemics, Cybernetics and Informatics: WMSCI 2019
Y1  - 2019
SP  - 33
EP  - 37
ER  - 
TY  - JOUR
A1  - Limpert, Nicolas
A1  - Wiesen, Patrick
A1  - Ferrein, Alexander
A1  - Kallweit, Stephan
A1  - Schiffer, Stefan
T1  - The ROSIN Project and its Outreach to South Africa
JF  - R&D Journal
Y1  - 2019
VL  - 35
SP  - 1
EP  - 6
ER  - 
TY  - CHAP
A1  - Funke, Harald
A1  - Beckmann, Nils
A1  - Abanteriba, Sylvester
T1  - Development and Testing of a FuelFlex Dry-Low-NOx Micromix Combustor for Industrial Gas Turbine Applications With Variable Hydrogen Methane Mixtures
T2  - ASME Turbo Expo 2019: Turbomachinery Technical Conference and Exposition.  June 17–21, 2019 Phoenix, Arizona, USA. Volume 4A: Combustion, Fuels, and Emissions
Y1  - 2019
SN  - 978-0-7918-5861-5
U6  - https://doi.org/10.1115/GT2019-90095
ER  - 
TY  - CHAP
A1  - Horikawa, Atsushi
A1  - Okada, Kunio
A1  - Uto, Takahiro
A1  - Uchiyama, Yuta
A1  - Wirsum, Manfred
A1  - Funke, Harald
A1  - Kusterer, Karsten
T1  - Application of Low NOx Micro-mix Hydrogen Combustion to 2MW Class Industrial Gas Turbine Combustor
T2  - Proceedings of International Gas Turbine Congress 2019 Tokyo, November 17-22, 2019, Tokyo, Japan
Y1  - 2019
SN  - 978-4-89111-010-9
N1  - IGTC-2019-129
SP  - 1
EP  - 6
ER  - 
TY  - CHAP
A1  - Funke, Harald
A1  - Beckmann, Nils
T1  - Flexible Fuel Operation of a Dry-Low-Nox Micromix Combustor with Variable Hydrogen Methane Mixtures
T2  - Proceedings of International Gas Turbine Congress 2019 Tokyo, November 17-22, 2019, Tokyo, Japan
Y1  - 2019
SN  - 978-4-89111-010-9
N1  - IGTC-2019-013
ER  - 
TY  - JOUR
A1  - Slabu, Ioana
A1  - Roeth, Anjali A.
A1  - Engelmann, Ulrich M.
A1  - Wiekhorst, Frank
A1  - Buhl, Eva M.
A1  - Neumann, Ulf P.
A1  - Schmitz-Rode, Thomas
T1  - Modeling of magnetoliposome uptake in human pancreatic tumor cells in vitro
JF  - Nanotechnology
Y1  - 2019
U6  - https://doi.org/10.1088/1361-6528/ab033e
SN  - 1361-6528
VL  - 30
IS  - 18
SP  - 184004
ER  - 
TY  - JOUR
A1  - Engelmann, Ulrich M.
A1  - Shasha, Carolyn
A1  - Teeman, Eric
A1  - Slabu, Iona
A1  - Krishnan, Kannan M.
T1  - Predicting size-dependent heating efficiency of magnetic nanoparticles from experiment and stochastic Néel-Brown Langevin simulation
JF  - Journal of Magnetism and Magnetic Materials
Y1  - 2019
U6  - https://doi.org/10.1016/j.jmmm.2018.09.041
SN  - 0304-8853
VL  - 471
IS  - 1
SP  - 450
EP  - 456
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Engelmann, Ulrich M.
A1  - Seifert, Julian
A1  - Mues, Benedikt
A1  - Roitsch, Stefan
A1  - Ménager, Christine
A1  - Schmidt, Annette M.
A1  - Slabu, Ioana
T1  - Heating efficiency of magnetic nanoparticles decreases with gradual immobilization in hydrogels
JF  - Journal of Magnetism and Magnetic Materials
Y1  - 2019
U6  - https://doi.org/10.1016/j.jmmm.2018.09.113
SN  - 0304-8853
VL  - 471
IS  - 1
SP  - 486
EP  - 494
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Dantism, Shahriar
A1  - Röhlen, Desiree
A1  - Wagner, Torsten
A1  - Wagner, P.
A1  - Schöning, Michael Josef
T1  - A LAPS-based differential sensor for parallelized metabolism monitoring of various bacteria
JF  - Sensors
N2  - Monitoring the cellular metabolism of bacteria in (bio)fermentation processes is crucial to control and steer them, and to prevent undesired disturbances linked to metabolically inactive microorganisms. In this context, cell-based biosensors can play an important role to improve the quality and increase the yield of such processes. This work describes the simultaneous analysis of the metabolic behavior of three different types of bacteria by means of a differential light-addressable potentiometric sensor (LAPS) set-up. The study includes Lactobacillus brevis, Corynebacterium glutamicum, and Escherichia coli, which are often applied in fermentation processes in bioreactors. Differential measurements were carried out to compensate undesirable influences such as sensor signal drift, and pH value variation during the measurements. Furthermore, calibration curves of the cellular metabolism were established as a function of the glucose concentration or cell number variation with all three model microorganisms. In this context, simultaneous (bio)sensing with the multi-organism LAPS-based set-up can open new possibilities for a cost-effective, rapid detection of the extracellular acidification of bacteria on a single sensor chip. It can be applied to evaluate the metabolic response of bacteria populations in a (bio)fermentation process, for instance, in the biogas fermentation process.
Y1  - 2019
U6  - https://doi.org/10.3390/s19214692
SN  - 1424-8220
VL  - 19
IS  - 21
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Karschuck, T. L.
A1  - Filipov, Y.
A1  - Bollella, P.
A1  - Schöning, Michael Josef
A1  - Katz, E.
T1  - Not-XOR (NXOR) logic gate based on an enzyme-catalyzed reaction
JF  - International Journal of Unconventional Computing
N2  - Enzyme-catalyzed reactions have been designed to mimic various Boolean logic gates in the general framework of unconventional biomolecular computing. While some of the logic gates, particularly OR, AND, are easy to realize with biocatalytic reactions and have been reported in numerous publications, some other, like NXOR, are very challenging and have not been realized yet with enzyme reactions. The paper reports on a novel approach to mimicking the NXOR logic gate using the bell-shaped enzyme activity dependent on pH values. Shifting pH from the optimum value to the acidic or basic values by using acid or base inputs (meaning 1,0 and 0,1 inputs) inhibits the enzyme reaction, while keeping the optimum pH (assuming 0,0 and 1,1 input combinations) preserves a high enzyme activity. The challenging part of the present approach is the selection of an enzyme with a well-demonstrated bell-shape activity dependence on the pH value. While many enzymes can satisfy this condition, we selected pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenase as this enzyme has the optimum pH center-located on the pH scale allowing the enzyme activity change by the acidic and basic pH shift from the optimum value corresponding to the highest activity. The present NXOR gate is added to the biomolecular “toolbox” as a new example of Boolean logic gates based on enzyme reactions.
Y1  - 2019
SN  - 1548-7199
VL  - 14
IS  - 3-4
SP  - 235
EP  - 242
PB  - Old City Publishing
CY  - Philadelphia
ER  - 
TY  - THES
A1  - Engelmann, Ulrich M.
T1  - Assessing magnetic fluid hyperthermia : magnetic relaxation simulation, modeling of nanoparticle uptake inside pancreatic tumor cells and in vitro efficacy
Y1  - 2019
SN  - 978-3-945954-58-4
N1  - Dissertation, Rheinisch-Westfälische Technische Hochschule Aachen, 2019
PB  - Infinite Science Publishing
CY  - Lübeck
ER  - 
TY  - JOUR
A1  - Finger, Felix
A1  - Bil, Cees
A1  - Braun, Carsten
T1  - Initial Sizing Methodology for Hybrid-Electric General Aviation Aircraft
JF  - Journal of Aircraft
Y1  - 2019
U6  - https://doi.org/10.2514/1.C035428
SN  - 1533-3868
VL  - 57
IS  - 2
SP  - 245
EP  - 255
ER  - 
TY  - CHAP
A1  - Luft, Angela
A1  - Gebhardt, Andreas
A1  - Balc, Nicolae
T1  - Challenges of additive manufacturing in production systems
T2  - Modern technologies in manufacturing (MTeM 2019)
Y1  - 2019
U6  - https://doi.org/10.1051/matecconf/201929901003
N1  - MATEC Web of Conferences 299; MTeM 2019
VL  - 299
IS  - Article 01003
ER  - 
TY  - CHAP
A1  - Abbas, Karim
A1  - Thurn, Laura
A1  - Kessler, Julia
A1  - Eichler, Fabian
T1  - Basic research of the consideration of additive manufactured lattice structures under thermoand fluid dynamic loads
T2  - Modern technologies in manufacturing (MTeM 2019)
Y1  - 2019
U6  - https://doi.org/10.1051/matecconf/201929901009
N1  - MATEC Web of Conferences 299; MTeM 2019
VL  - 299
IS  - Article 01009
ER  - 
TY  - CHAP
A1  - Eichler, Fabian
A1  - Skupin, Marco
A1  - Thurn, Laura
A1  - Kasch, Susanne
A1  - Schmidt, Thomas
T1  - Operating limits for beam melting of glass materials
T2  - Modern Technologies in Manufacturing (MTeM 2019)
N2  - Laser-based Additive Manufacturing (AM) processes for the use of metals out of the powder bed have been investigated profusely and are prevalent in industry. Although there is a broad field of application, Laser Powder Bed Fusion (LPBF), also known as Selective Laser Melting (SLM) of glass is not fully developed yet. The material properties of glass are significantly different from the investigated metallic material for LPBF so far. As such, the process cannot be transferred, and the parameter limits and the process sequence must be redefined for glass. Starting with the characterization of glass powders, a parameter field is initially confined to investigate the process parameter of different glass powder using LPBFprocess. A feasibility study is carried out to process borosilicate glass powder. The effects of process parameters on the dimensional accuracy of fabricated parts out of borosilicate and hints for the post-processing are analysed and presented in this paper.
Y1  - 2019
U6  - https://doi.org/10.1051/matecconf/201929901004
N1  - MATEC Web of Conferences 299; MTeM 2019
VL  - 299
IS  - Article 01004
ER  - 
TY  - CHAP
A1  - Baader, Fabian
A1  - Keller, Denis
A1  - Lehmann, Raphael
A1  - Gerber, Lukas
A1  - Reiswich, Martin
A1  - Dachwald, Bernd
A1  - Förstner, Roger
T1  - Operating melting probes for ice penetration under sublimation  conditions and in reduced gravity on a sounding rocket
T2  - Proceedings of the 24th ESA Symposium on European Rocket and Balloon Programmes and related Research
Y1  - 2019
SN  - 0379-6566
N1  - 24th PAC Symposium 2019
ER  - 
TY  - CHAP
A1  - Ludowicy, Jonas
A1  - Rings, René
A1  - Finger, Felix
A1  - Braun, Carsten
A1  - Bil, Cees
T1  - Impact of Propulsion Technology Levels on the Sizing and Energy Consumption for Serial HybridElectric General Aviation Aircraft
T2  - Asia Pacific International Symposium on Aerospace Technology. APISAT 2019
Y1  - 2019
ER  - 
TY  - CHAP
A1  - Rings, René
A1  - Ludowicy, Jonas
A1  - Finger, Felix
A1  - Braun, Carsten
A1  - Bil, Cees
T1  - Sensitivity Analysis of General Aviation Aircraft with Parallel Hybrid-Electric Propulsion Systems
T2  - Asia Pacific International Symposium on Aerospace Technology. APISAT 2019
Y1  - 2019
ER  - 
TY  - CHAP
A1  - Gerhards, Benjamin
A1  - Schleser, Markus
A1  - Otten,, Christian
A1  - Schwarz, Alexander
A1  - Gebhardt, Andreas
T1  - Innovative Laser Beam Joining Technology for Additive Manufactured Parts
T2  - Conference Proceedings 72nd IIW Annual Assembly and International Conference, 7-12 July 2019, Bratislava
Y1  - 2019
SP  - 1
EP  - 8
ER  - 
TY  - CHAP
A1  - Gerhards, Benjamin
A1  - Schleser, Markus
A1  - Otten, Christian
T1  - Advancements of mobile vacuum laser welding for industrial thick sheet applications
T2  - Conference Proceedings 72nd IIW Annual Assembly and International Conference, 7-12 July 2019, Bratislava
Y1  - 2019
SP  - 1
EP  - 8
ER  - 
TY  - CHAP
A1  - Valero, Daniel
A1  - Kramer, Matthias
A1  - Bung, Daniel Bernhard
A1  - Chanson, Hubert
T1  - A stochastic bubble generator for air-water flow research
T2  - E-proceedings of the 38th IAHR World Congress, September 1-6, 2019, Panama City, Panama
Y1  - 2019
U6  - https://doi.org/10.3850/38WC092019-0909
SP  - 5714
EP  - 5721
ER  - 
TY  - CHAP
A1  - Tullis, Blake P.
A1  - Crookston, Brian M.
A1  - Bung, Daniel Bernhard
T1  - Weir head-discharge relationships: A multi-lab exercise
T2  - E-proceedings of the 38th IAHR World Congress  September 1-6, 2019, Panama City, Panama
Y1  - 2019
SP  - 1
EP  - 15
ER  - 
TY  - JOUR
A1  - Engel, Mareike
A1  - Gemünde, Andre
A1  - Holtmann, Dirk
A1  - Müller-Renno, Christine
A1  - Ziegler, Christiane
A1  - Tippkötter, Nils
A1  - Ulber, Roland
T1  - Clostridium acetobutylicum’s connecting world: cell appendage formation in bioelectrochemical systems
JF  - ChemElectroChem
N2  - Bacterial cell appendix formation supports cell-cell interaction, cell adhesion and cell movement. Additionally, in bioelectrochemical systems (BES), cell appendages have been shown to participate in extracellular electron transfer. In this work, the cell appendix formation of Clostridium acetobutylicum in biofilms of a BES are imaged and compared with conventional biofilms. Under all observed conditions, the cells possess filamentous appendages with a higher number and density in the BES. Differences in the amount of extracellular polymeric substance in the biofilms of the electrodes lead to the conclusion that the cathode can be used as electron donor and the anode as electron acceptor by C. acetobutylicum. When using conductive atomic force microscopy, a current response of about 15 nA is found for the cell appendages from the BES. This is the first report of conductivity for clostridial cell appendices and represents the basis for further studies on their role for biofilm formation and electron transfer.
Y1  - 2019
U6  - https://doi.org/10.1002/celc.201901656
SN  - 2196-0216
VL  - 7
IS  - 2
SP  - 414
EP  - 420
PB  - Wiley
CY  - Weinheim
ER  -