TY  - CHAP
A1  - Birgel, Stefan
A1  - Leschinger, Tim
A1  - Wegmann, Kilian
A1  - Staat, Manfred
ED  - Erni, Daniel
ED  - Fischerauer, Alice
ED  - Himmel, Jörg
ED  - Seeger, Thomas
ED  - Thelen, Klaus
T1  - Calculation of muscle forces and joint reaction loads in shoulder area via an OpenSim based computer calculation
T2  - 2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West
Y1  - 2017
SN  - 978-3-9814801-9-1
U6  - https://doi.org/10.17185/duepublico/43984
N1  - A young researchers track of the 7th IEEE Workshop & SENSORICA 2017
N1  - In der Druckausgabe des Abstractbandes ist dieser Beitrag lose als Erratum beigefügt.
SP  - 116
EP  - 117
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - BOOK
A1  - Staat, Manfred
A1  - Erni, Daniel
T1  - Symposium Proceedings; 3rd YRA MedTech Symposium 2019: May 24 / 2019 / FH Aachen
Y1  - 2019
SN  - 978-3-940402-22-6
U6  - https://doi.org/10.17185/duepublico/48750
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - BOOK
A1  - Staat, Manfred
A1  - Heitzer, Michael
T1  - Numerical methods for limit and shakedown analysis. Deterministic and probabilistic problems.
Y1  - 2003
SN  - 3-00-010001-6
N1  - NIC Series Vol. 15 / Ed. by Staat, M; Heitzer, M.
PB  - John von Neumann Institute for Computing (NIC)
CY  - Jülich
ER  - 
TY  - JOUR
A1  - Albanna, Walid
A1  - Conzen, Catharina
A1  - Weiss, Miriam
A1  - Clusmann, Hans
A1  - Fuest, Matthias
A1  - Mueller, Marguerite
A1  - Brockmann, Marc Alexander
A1  - Vilser, Walthard
A1  - Schmidt-Trucksäss, Arno
A1  - Hoellig, Anke
A1  - Seiz, Marcel
A1  - Thomé, Claudius
A1  - Kotliar, Konstantin
A1  - Schubert, Gerrit Alexander
T1  - Retinal Vessel Analysis (RVA) in the context of subarachnoid hemorrhage: A proof of concept study
JF  - PLoS ONE
N2  - Background
Timely detection of impending delayed cerebral ischemia after subarachnoid hemorrhage (SAH) is essential to improve outcome, but poses a diagnostic challenge. Retinal vessels as an embryological part of the intracranial vasculature are easily accessible for analysis and may hold the key to a new and non-invasive monitoring technique. This investigation aims to determine the feasibility of standardized retinal vessel analysis (RVA) in the context of SAH.

Methods
In a prospective pilot study, we performed RVA in six patients awake and cooperative with SAH in the acute phase (day 2–14) and eight patients at the time of follow-up (mean 4.6±1.7months after SAH), and included 33 age-matched healthy controls. Data was acquired using a manoeuvrable Dynamic Vessel Analyzer (Imedos Systems UG, Jena) for examination of retinal vessel dimension and neurovascular coupling.

Results
Image quality was satisfactory in the majority of cases (93.3%). In the acute phase after SAH, retinal arteries were significantly dilated when compared to the control group (124.2±4.3MU vs 110.9±11.4MU, p<0.01), a difference that persisted to a lesser extent in the later stage of the disease (122.7±17.2MU, p<0.05). Testing for neurovascular coupling showed a trend towards impaired primary vasodilation and secondary vasoconstriction (p = 0.08, p = 0.09 resp.) initially and partial recovery at the time of follow-up, indicating a relative improvement in a time-dependent fashion.

Conclusion
RVA is technically feasible in patients with SAH and can detect fluctuations in vessel diameter and autoregulation even in less severely affected patients. Preliminary data suggests potential for RVA as a new and non-invasive tool for advanced SAH monitoring, but clinical relevance and prognostic value will have to be determined in a larger cohort.
Y1  - 2016
U6  - https://doi.org/10.1371/journal.pone.0158781
SN  - 1932-6203
VL  - 11
IS  - 7
PB  - PLOS
CY  - San Francisco
ER  -