TY  - CHAP
A1  - Gorzalka, Philip
A1  - Dahlke, Dennis
A1  - Göttsche, Joachim
A1  - Israel, Martin
A1  - Patel, Dhruvkumar
A1  - Prahl, Christoph
A1  - Schmiedt, Jacob Estevam
A1  - Frommholz, Dirk
A1  - Hoffschmidt, Bernhard
A1  - Linkiewicz, Magdalena
T1  - Building Tomograph–From Remote Sensing Data of Existing Buildings to Building Energy Simulation Input
T2  - EBC, Annex 71, Fifth expert meeting, October 17-19, 2018, Innsbruck, Austria
Y1  - 2018
ER  - 
TY  - PAT
A1  - Berndt, Heinz
A1  - Höcker, Hartwig
A1  - Kuropka, Rolf
A1  - Kinkel, Joachim
T1  - Silane coated inorganic materials for chromatography : United States Patent
Y1  - 1991
PB  - [The United States Patent and Trademark Office]
CY  - [Alexandria, VA u.a.]
ER  - 
TY  - JOUR
A1  - Wilson, Ian D.
A1  - Wilson, Claire E.
A1  - Scheer, Nico
A1  - Dickie, A.P.
A1  - Schreiter, K.
A1  - Wilson, E. M.
A1  - Riley, R. J.
A1  - Wehr, R.
A1  - Bial, J.
T1  - The Pharmacokinetics and Metabolism of Lumiracoxib in Chimeric Humanized and Murinized FRG Mice
JF  - Biochemical pharmacology
Y1  - 2017
U6  - https://doi.org/10.1016/j.bcp.2017.03.015
SN  - 1873-2968
VL  - Volume 135
SP  - 139
EP  - 150
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Buxbaum, Bernd
A1  - Schwarte, Rudolf
A1  - Ringbeck, Thorsten
ED  - Kamerman, Gary W.
T1  - Synchronization in spread spectrum laser radar systems based on PMD-DLL
T2  - Laser radar technology and applications V : 26 - 28 April 2000, Orlando, USA. - (SPIE proceedings series ; 4035)
Y1  - 2000
SN  - 0-8194-3661-5
SN  - 0038-7355
SN  - 0361-0748
SN  - 0277-786X
N1  - Laser radar technology and applications <5, 2000, Orlando, Fla.>
SP  - 204
EP  - 216
PB  - SPIE
CY  - Bellingham, Wash.
ER  - 
TY  - CHAP
A1  - Wolf, Martin R.
A1  - Wiese, Ute
T1  - A comparative transformation model for process changes using serious games
T2  - 2013 IEEE 2nd International Conference on Serious Games and Applications for Health (SeGAH): proceedings of a meeting held 2-3 May 2013, Algarve, Portugal
Y1  - 2013
SN  - 978-1-4673-6164-4
U6  - https://doi.org/10.1109/SeGAH.2013.6665307
SP  - 64
EP  - 70
PB  - Institute of Electrical and Electronics Engineers (IEEE)
CY  - Piscataway, NJ
ER  - 
TY  - JOUR
A1  - Hough, Lindsay B.
A1  - Nalwalk, Julia W.
A1  - Ding, Xinxin
A1  - Scheer, Nico
T1  - Opioid Analgesia in P450 Gene Cluster Knockout Mice: A Search for Analgesia-Relevant Isoforms
JF  - Drug Metabolism and Disposition
Y1  - 2015
U6  - https://doi.org/10.1124/dmd.115.065490
SN  - 1521-009x
VL  - 43
IS  - 9
SP  - 1326
EP  - 1330
ER  - 
TY  - CHAP
A1  - Laack, Walter van
T1  - Schnittstelle Tod: Wo stehen wir nach 40 Jahren NTE-Forschung?
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:101:1-201603132912
SN  - 978-3-936624-30-4 (Print-Ausgabe)
SN  - 978-3-936624-32-8 (Online-Ausgabe)
N1  - Tagungsbeiträge des 4. Europäischen Seminars am 07. November 2015 in Aachen zum Thema Nahtoderfahrungen mit dem Serientitel: "Schnittstelle Tod"
PB  - van Laack GmbH
CY  - Aachen
ER  - 
TY  - RPRT
A1  - Adomeit, G.
A1  - Willms, Herbert
T1  - Experimental investigation of the acceleration of deflagration in wake flow : final report. - (Euratom-publications-EUR ; 9593 : Nuclear science and technology)
Y1  - 1984
SN  - 92-825-4699-3
PB  - Commission of the European Communities
CY  - Luxembourg
ER  - 
TY  - JOUR
A1  - Haeger, Gerrit
A1  - Probst, Johanna
A1  - Jaeger, Karl-Erich
A1  - Bongaerts, Johannes
A1  - Siegert, Petra
T1  - Novel aminoacylases from Streptomyces griseus DSM 40236 and their recombinant production in Streptomyces lividans
JF  - FEBS Open Bio
N2  - Amino acid-based surfactants are valuable compounds for cosmetic formulations. The chemical synthesis of acyl-amino acids is conventionally performed by the Schotten-Baumann reaction using fatty acyl chlorides, but aminoacylases have also been investigated for use in biocatalytic synthesis with free fatty acids. Aminoacylases and their properties are diverse; they belong to different peptidase families and show differences in substrate specificity and biocatalytic potential. Bacterial aminoacylases capable of synthesis have been isolated from Burkholderia, Mycolicibacterium, and Streptomyces. Although several proteases and peptidases from S. griseus have been described, no aminoacylases from this species have been identified yet. In this study, we investigated two novel enzymes produced by S. griseus DSM 40236ᵀ . We identified and cloned the respective genes and recombinantly expressed an α-aminoacylase (EC 3.5.1.14), designated SgAA, and an ε-lysine acylase (EC 3.5.1.17), designated SgELA, in S. lividans TK23. The purified aminoacylase SgAA was biochemically characterized, focusing on its hydrolytic activity to determine temperature- and pH optima and stabilities. The aminoacylase could hydrolyze various acetyl-amino acids at the Nα -position with a broad specificity regarding the sidechain. Substrates with longer acyl chains, like lauroyl-amino acids, were hydrolyzed to a lesser extent. Purified aminoacylase SgELA specific for the hydrolysis of Nε -acetyl-L-lysine was unstable and lost its enzymatic activity upon storage for a longer period but could initially be characterized. The pH optimum of SgELA was pH 8.0. While synthesis of acyl-amino acids was not observed with SgELA, SgAA catalyzed the synthesis of lauroyl-methionine.
KW  - Streptomyces lividans
KW  - recombinant expression
KW  - Streptomyces griseus
KW  - ε-lysine acylase
KW  - α-aminoacylase
Y1  - 2023
U6  - https://doi.org/10.1002/2211-5463.13723
SN  - 2211-5463
N1  - Corresponding author: Petra Siegert
VL  - 13
IS  - 12
SP  - 2224
EP  - 2238
PB  - Wiley
CY  - Hoboken, NJ
ER  - 
TY  - GEN
A1  - Hering, T.
A1  - Pasteur, A.
A1  - Wollny, S.
A1  - Ulber, Roland
A1  - Tippkötter, Nils
T1  - Magnetische Separation von Gold-Nanopartikeln zur Gluconsäure-Produktion durch Hochgradient-Magnetseparation im Labormaßstab
T2  - Chemie Ingenieur Technik
N2  - Bei der Verarbeitung nachwachsender Rohstoffe entsteht aus Cellulose oder Stärke u. a. das wichtige Produkt Glucose. Diese niedermolekulare Kohlenhydratquelle wird üblicherweise als Substrat für biotechnologische und chemische Synthesen verwendet. Ein wirtschaftlich interessantes Oxidationsprodukt der Glucose ist Gluconsäure, die beispielsweise als Lebensmittelzusatzstoff (E 574), in der Medizin und Metallindustrie Verwendung findet. Die Umsetzung des Monosaccharids zu Gluconsäure erfolgt entweder durch mikrobielle Fermentation oder der Oxidation an heterogenen Katalysatoren. Die Zielsetzung der Studie ist die Untersuchung der Glucoseoxidation an magnetisierbaren Gold-Nanopartikeln unter nachfolgender Bypass-Separation des Katalysators mittels einer neuen Mini-HGMS-Einheit (Hochgradient-Magnetseparation). Dieser Filtertyp ermöglicht die selektive Trennung magnetischer Partikel aus Suspensionen mit hohem Feststoffgehalt oder Viskosität. Erste Ergebnisse zeigen eine Beladungskapazität des selbstkonstruierten Mini-HGMS von 550 mg goldbeschichteter magnetisierbarer Nanopartikel. Die Oxidation erfolgt bei einem pH-Wertvon 9, bei 40 °C und mit 100 mM Glucose in einem begasten Rührkesselreaktor. Das System soll zukünftig zum Katalysatorrecycling von hochviskosen und Feststoffbelasteten Produktströmen aus Bioraffinerien eingesetzt werden.
Y1  - 2014
U6  - https://doi.org/10.1002/cite.201450265
SN  - 0009-286X
SN  - 1522-2640 (eISSN)
N1  - ProcessNet-Jahrestagung 2014 und 31. DECHEMA-Jahrestagung der Biotechnologen, 30. September - 2. Oktober 2014, Eurogress Aachen
VL  - 86
IS  - 9
SP  - 1501
PB  - Wiley-VCH
CY  - Weinheim
ER  -