TY  - PAT
A1  - Frauenrath, Tobias
A1  - Niendorf, Thoralf
T1  - MRT-Vorrichtung und Verfahren zum Betreiben einer MRT-Vorrichtung
T1  - Magnetic resonance tomography (MRT) apparatus and method of operating a magnetic resonance (MR) apparatus
T1  - Appareil de tomographie par résonance magnétique et procédé de fonctionnement d'un appareil à résonance magnétique
N2  - A magnetic resonance tomography (MRT) apparatus (1) for the examination of a body (14) comprises parameter acquisition devices (13) for the acquisition of cardiovascular parameters of the body (14) and a control device (15) in communication with the parameter acquisition devices (13) for synchronizing the imaging, wherein the control device (15) is adapted to analyse the data of at least two parameter acquisition devices (13) and to output a control signal based on the analysis.
Y1  - 2012
ER  - 
TY  - JOUR
A1  - Bohrn, U.
A1  - Stütz, E.
A1  - Fuchs, K.
A1  - Fleischer, M.
A1  - Schöning, Michael Josef
A1  - Wagner, P.
T1  - Monitoring of irritant gas using a whole-cell-based sensor system
JF  - Sensors and Actuators B: Chemical
N2  - Cell-based sensors for the detection of gases have long been underrepresented, due to the cellular requirement of being cultured in a liquid environment. In this work we established a cell-based gas biosensor for the detection of toxic substances in air, by adapting a commercial sensor chip (Bionas®), previously used for the measurement of pollutants in liquids. Cells of the respiratory tract (A549, RPMI 2650, V79), which survive at a gas phase in a natural context, are used as biological receptors. The physiological cell parameters acidification, respiration and morphology are continuously monitored in parallel. Ammonia was used as a highly water-soluble model gas to test the feasibility of the sensor system. Infrared measurements confirmed the sufficiency of the medium draining method. This sensor system provides a basis for many sensor applications such as environmental monitoring, building technology and public security.
Y1  - 2012
U6  - https://doi.org/10.1016/j.snb.2012.05.088
SN  - 0925-4005
VL  - 175
SP  - 208
EP  - 217
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Reisgen, Uwe
A1  - Schleser, Markus
A1  - Mokrov, Oleg
A1  - Zabirov, Alexander
A1  - Füssel, Uwe
A1  - Schnick, Michael
A1  - Hertel, Martin
A1  - Jaeckel, Sebastian
T1  - Modelling and visualisation of the GMA process
JF  - Welding and Cutting
Y1  - 2012
SN  - 1612-3433
VL  - 11
IS  - 4
SP  - 242
EP  - 249
PB  - DVS Verlag
CY  - Düsseldorf
ER  - 
TY  - CHAP
A1  - Alexopoulos, Spiros
A1  - Rau, Christoph
A1  - Hoffschmidt, Bernhard
A1  - Breitbach, Gerd
A1  - Latzke, Markus
T1  - Modelling and validation of a transient heat recovery steam generator of the solar tower power plant Juelich
T2  - Eurosun 2012 : Solar energy for a brighter future : conference proceedings : Rijeka, 18.-22.09.2012
Y1  - 2012
SP  - ID 97
CY  - Rijeka
ER  - 
TY  - JOUR
A1  - Reisgen, Uwe
A1  - Schleser, Markus
A1  - Mokrov, Oleg
A1  - Zabirov, Alexander
A1  - Füssel, Uwe
A1  - Schnick, Michael
A1  - Hertel, Martin
A1  - Jaeckel, Sebastian
T1  - Modellierung und Visualisierung der MSG-Lichtbogenprozesse
JF  - Schweissen und Schneiden : Fachzeitschrift für Schweißen und verwandte Verfahren
Y1  - 2012
SN  - 0036-7184
VL  - 64
IS  - 4
SP  - 166
EP  - 174
PB  - DVS Verlag
CY  - Düsseldorf
ER  - 
TY  - JOUR
A1  - Scheer, Nico
A1  - Kapelyukh, Yury
A1  - McEwan, Jillian
A1  - Beuger, Vincent
A1  - Stanley, Lesley A.
A1  - Rode, Anja
A1  - Wolf, C. Roland
T1  - Modeling Human Cytochrome P450 2D6 Metabolism and Drug-drug Interaction by a Novel Panel of Knockout and Humanized Mouse Lines
JF  - Molecular Pharmacology
N2  - The highly polymorphic human cytochrome P450 2D6 enzyme is involved in the metabolism of up to 25% of all marketed drugs and accounts for significant individual differences in response to CYP2D6 substrates. Because of the differences in the multiplicity and substrate specificity of CYP2D family members among species, it is difficult to predict pathways of human CYP2D6-dependent drug metabolism on the basis of animal studies. To create animal models that reflect the human situation more closely and that allow an in vivo assessment of the consequences of differential CYP2D6 drug metabolism, we have developed a novel straightforward approach to delete the entire murine Cyp2d gene cluster and replace it with allelic variants of human CYP2D6. By using this approach, we have generated mouse lines expressing the two frequent human protein isoforms CYP2D6.1 and CYP2D6.2 and an as yet undescribed variant of this enzyme, as well as a Cyp2d cluster knockout mouse. We demonstrate that the various transgenic mouse lines cover a wide spectrum of different human CYP2D6 metabolizer phenotypes. The novel humanization strategy described here provides a robust approach for the expression of different CYP2D6 allelic variants in transgenic mice and thus can help to evaluate potential CYP2D6-dependent interindividual differences in drug response in the context of personalized medicine.
Y1  - 2012
U6  - https://doi.org/10.1124/mol.111.075192
SN  - 1521-0111
VL  - 81
IS  - 1
SP  - 63
EP  - 72
PB  - ASPET
CY  - Bethesda, Md.
ER  - 
TY  - JOUR
A1  - Verbanella, Stresa
A1  - Fabo, Sabine
T1  - Mit Pinsel und Farbe hacken : Interview mit Sabine Fabo
T1  - Hacking with paint and brush : interview with Sabine Fabo
JF  - Remotewords.net
N2  - Remotewords makes its mark on the picturesque "Bar Verbanella”, located in Stresa near Isola Bella on Lago Maggiore. The words CUM GRANO SALIS (with a grain of salt) by Sabine Fabo, art theorist on media contexts, were applied to its roof in collaboration with the German-Italian art organization "Lo spirito del Lago".
KW  - Guerrillawerbung
KW  - Parasitäre Strategie
Y1  - 2012
ER  - 
TY  - JOUR
A1  - Miyamoto, Ko-ichiro
A1  - Kaneko, Kazumi
A1  - Matsuo, Akira
A1  - Wagner, Torsten
A1  - Kanoh, Shiníchiro
A1  - Schöning, Michael Josef
A1  - Yoshinobu, Tatsuo
T1  - Miniaturized chemical imaging sensor system using an OLED display panel
JF  - Sensors and Actuators B: Chemical
N2  - The chemical imaging sensor is a semiconductor-based chemical sensor that can visualize the two-dimensional distribution of specific ions or molecules in the solution. In this study, we developed a miniaturized chemical imaging sensor system with an OLED display panel as a light source that scans the sensor plate. In the proposed configuration, the display panel is placed directly below the sensor plate and illuminates the back surface. The measured area defined by illumination can be arbitrarily customized to fit the size and the shape of the sample to be measured. The waveform of the generated photocurrent, the current–voltage characteristics and the pH sensitivity were investigated and pH imaging with this miniaturized system was demonstrated.
KW  - LAPS
KW  - Light-addressable potentiometric sensor
KW  - Chemical imaging sensor
KW  - Organic light-emitting diode display
Y1  - 2012
U6  - https://doi.org/10.1016/j.snb.2011.02.029
SN  - 0925-4005
N1  - Part of special issue "Eurosensors XXIV, 2010"
VL  - 170
SP  - 82
EP  - 87
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Yoshinobu, Tatsuo
A1  - Miyamoto, Ko-Ichiro
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
ED  - Yamaguchi, Takami
T1  - Miniaturized and high-speed chemical imaging systems
T2  - Nano-Biomedical Engineering 2012. Proceedings of the Tohoku University Global Centre of Excellence Programme, Sakura Hall, Tohoku University, Sendai Japan, 5 – 6 March 2012
Y1  - 2012
U6  - https://doi.org/10.1142/9781848169067_0045
SP  - 386
EP  - 395
PB  - World Scientific
CY  - Singapur
ER  - 
TY  - PAT
A1  - Ahlborn, Kristina
A1  - Gerlach, Frank
A1  - Iken, Heiko
A1  - Schöning, Michael Josef
A1  - Vonau, Winfried
T1  - Miniaturisierte, potentiometrische Indikatorelektrode und Verfahren zu deren Herstellung : Offenlegungsschrift
Y1  - 2012
ER  -