Frequency Mixing Magnetic Detection Setup Employing Permanent Ring Magnets as a Static Offset Field Source

  • Frequency mixing magnetic detection (FMMD) has been explored for its applications in fields of magnetic biosensing, multiplex detection of magnetic nanoparticles (MNP) and the determination of core size distribution of MNP samples. Such applications rely on the application of a static offset magnetic field, which is generated traditionally with an electromagnet. Such a setup requires a current source, as well as passive or active cooling strategies, which directly sets a limitation based on the portability aspect that is desired for point of care (POC) monitoring applications. In this work, a measurement head is introduced that involves the utilization of two ring-shaped permanent magnets to generate a static offset magnetic field. A steel cylinder in the ring bores homogenizes the field. By variation of the distance between the ring magnets and of the thickness of the steel cylinder, the magnitude of the magnetic field at the sample position can be adjusted. Furthermore, the measurement setup is compared to the electromagnet offset module based on measured signals and temperature behavior.

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Metadaten
Author:Ali Mohammad PourshahidiORCiD, Stefan AchtsnichtORCiD, Andreas OffenhäusserORCiD, Hans-Joachim KrauseORCiD
DOI:https://doi.org/10.3390/s22228776
ISSN:1424-8220
Parent Title (English):Sensors
Publisher:MDPI
Place of publication:Basel
Editor:Andreas Offenhäusser
Document Type:Article
Language:English
Year of Completion:2022
Date of first Publication:2022/11/10
Date of the Publication (Server):2023/01/25
Tag:biosensors; frequency mixing magnetic detection; magnetic nanoparticles; magnetic sensors
Volume:22
Issue:22
Length:12 Seiten
Link:https://doi.org/10.3390/s22228776
Zugriffsart:weltweit
Institutes:FH Aachen / INB - Institut für Nano- und Biotechnologien
collections:Open Access
Verlag / MDPI
Licence (German):License LogoCreative Commons - Namensnennung