Light-addressable Potentiometric Sensors and Light–addressable Electrodes as a Combined Sensor-and-manipulator Microsystem with High Flexibility
- This work describes the novel combination of the light-addressable electrode (LAE) and the light-addressable potentiometric sensor (LAPS) into a microsystem set-up. Both the LAE as well as the LAPS shares the principle of addressing the active spot by means of a light beam. This enables both systems to manipulate resp. to detect an analyte with a high spatial resolution. Hence, combining both principles into a single set-up enables the active stimulation e.g., by means of electrolysis and a simultaneous observation e.g., the response of an entrapped biological cell by detection of extracellular pH changes. The work will describe the principles of both technologies and the necessary steps to integrate them into a single set-up. Furthermore, examples of application and operation of such systems will be presented.
| Author: | Torsten WagnerORCiD, N. Shigiahara, K. Miyamoto, J. Suzurikawa, F. Finger, Michael Josef SchöningORCiD, T. Yoshinobu |
|---|---|
| DOI: | https://doi.org/10.1016/j.proeng.2012.09.290 |
| ISSN: | 1877-7058 |
| Parent Title (English): | Procedia Engineering |
| Publisher: | Elsevier |
| Place of publication: | Amsterdam |
| Document Type: | Article |
| Language: | English |
| Year of Completion: | 2012 |
| Date of the Publication (Server): | 2012/12/18 |
| Issue: | 47 |
| First Page: | 890 |
| Last Page: | 893 |
| Note: | Part of special issue "26th European Conference on Solid-State Transducers, EUROSENSOR 2012" |
| Link: | https://doi.org/10.1016/j.proeng.2012.09.290 |
| Zugriffsart: | campus |
| Institutes: | FH Aachen / Fachbereich Medizintechnik und Technomathematik |
| FH Aachen / INB - Institut für Nano- und Biotechnologien | |
| collections: | Verlag / Elsevier |
