Comparison of label-free ACh-imaging sensors based on CCD and LAPS
- Semiconductor-based chemical imaging sensors, like the light-addressable potentiometric sensor (LAPS) or the pH-imaging sensor based on a charge-coupled device (CCD), are becoming a powerful tool for label-free imaging of biological phenomena. We have proposed a polyion-based enzymatic membrane to develop an acetylcholine (ACh) imaging sensor for neural cell-activity observations. In this study, a CCD-type ACh-imaging sensor and a LAPS-type ACh-imaging sensor were fabricated and the prospect of both sensors was clarified by making a comparison of their basic characteristics.
| Author: | Frederik WernerORCiD, Shoko Takenaga, Hidenori Taki, Kazuaki Sawada, Michael Josef SchöningORCiD |
|---|---|
| ISBN: | 0925-4005 |
| Parent Title (English): | Sensors and Actuators B: Chemical (2012) |
| Publisher: | Elsevier |
| Place of publication: | Amsterdam |
| Document Type: | Article |
| Language: | English |
| Year of Completion: | 2013 |
| Date of the Publication (Server): | 2012/12/18 |
| Volume: | 177 |
| First Page: | 745 |
| Last Page: | 752 |
| Link: | https://doi.org/10.1016/j.snb.2012.11.012 |
| Zugriffsart: | campus |
| Institutes: | FH Aachen / Fachbereich Medizintechnik und Technomathematik |
| FH Aachen / INB - Institut für Nano- und Biotechnologien | |
| collections: | Verlag / Elsevier |
