Visualization of Defects on a Cultured Cell Layer by Utilizing Chemical Imaging Sensor
- The chemical imaging sensor is a field-effect sensor which is able to visualize both the distribution of ions (in LAPS mode) and the distribution of impedance (in SPIM mode) inthe sample. In this study, a novel wound-healing assay is proposed, in which the chemical imaging sensor operated in SPIM mode is applied to monitor the defect of a cell layer brought into proximity of the sensing surface.A reduced impedance inside the defect, which was artificially formed ina cell layer, was successfully visualized in a photocurrent image.
| Author: | Ko-ichiro Miyamoto, Yu Bing, Torsten WagnerORCiD, Tatsuo Yoshinobu, Michael Josef SchöningORCiD |
|---|---|
| DOI: | https://doi.org/10.1016/j.proeng.2015.08.806 |
| ISSN: | 1877-7058 |
| Parent Title (English): | Procedia Engineering |
| Publisher: | Elsevier |
| Place of publication: | Amsterdam |
| Document Type: | Article |
| Language: | English |
| Year of Completion: | 2015 |
| Date of the Publication (Server): | 2015/10/01 |
| Volume: | 120 |
| First Page: | 936 |
| Last Page: | 939 |
| Note: | Part of special issue "Eurosensors 2015" |
| Link: | https://doi.org/10.1016/j.proeng.2015.08.806 |
| Zugriffsart: | weltweit |
| Institutes: | FH Aachen / Fachbereich Medizintechnik und Technomathematik |
| FH Aachen / INB - Institut für Nano- und Biotechnologien | |
| collections: | Verlag / Elsevier |
| Licence (German): |  Creative Commons - Namensnennung-Nicht kommerziell-Keine Bearbeitung |
