Light-addressable potentiometric sensor as a sensing element in plug-based microfluidic devices
- A plug-based microfluidic system based on the principle of the light-addressable potentiometric sensor (LAPS) is proposed. The LAPS is a semiconductor-based chemical sensor, which has a free addressability of the measurement point on the sensing surface. By combining a microfluidic device and LAPS, ion sensing can be performed anywhere inside the microfluidic channel. In this study, the sample solution to be measured was introduced into the channel in a form of a plug with a volume in the range of microliters. Taking advantage of the light-addressability, the position of the plug could be monitored and pneumatically controlled. With the developed system, the pH value of a plug with a volume down to 400 nL could be measured. As an example of plug-based operation, two plugs were merged in the channel, and the pH change was detected by differential measurement.
| Author: | Ko-Ichiro Miyamoto, Takuya Sato, Minami Abe, Torsten WagnerORCiD, Michael Josef SchöningORCiD, Tatsuo Yoshinobu |
|---|---|
| DOI: | https://doi.org/10.3390/mi7070111 |
| ISSN: | 2072-666X |
| Parent Title (English): | Micromachines |
| Publisher: | MDPI |
| Place of publication: | Basel |
| Document Type: | Article |
| Language: | English |
| Year of Completion: | 2016 |
| Date of the Publication (Server): | 2016/07/06 |
| Tag: | chemical sensor; light-addressable potentiometric sensor; plug-based microfluidic device |
| Volume: | 7 |
| Issue: | 7 |
| First Page: | 111 |
| Note: | This article belongs to the Special Issue "Micro/Nano Devices for Chemical Analysis" |
| Link: | https://doi.org/10.3390/mi7070111 |
| Zugriffsart: | weltweit |
| Institutes: | FH Aachen / Fachbereich Medizintechnik und Technomathematik |
| FH Aachen / INB - Institut für Nano- und Biotechnologien | |
| collections: | Verlag / MDPI |
| Open Access / Gold | |
| Licence (German): |  Creative Commons - Namensnennung |
