Field-effect Devices Functionalised with Gold-Nanoparticle/Macromolecule Hybrids: New Opportunities for a Label-Free Biosensing
- Field-effect capacitive electrolyte-insulator-semiconductor (EIS) sensors functionalised with citrate-capped gold nanoparticles (AuNP) have been used for the electrostatic detection of macromolecules by their intrinsic molecular charge. The EIS sensor detects the charge changes in the AuNP/macromolecule hybrids induced by the adsorption or binding events. A feasibility of the proposed detection scheme has been exemplary demonstrated by realising EIS sensors for the detection of poly-D-lysine molecules.
Author: | Arshak PoghossianORCiD, M. H. Weil, Matthias Bäcker, D. Mayer, Michael Josef SchöningORCiD |
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DOI: | https://doi.org/10.1016/j.proeng.2012.09.136 |
ISSN: | 1877-7058 |
Parent Title (English): | Procedia Engineering |
Publisher: | Elsevier |
Place of publication: | Amsterdam |
Document Type: | Article |
Language: | English |
Year of Completion: | 2012 |
Date of the Publication (Server): | 2012/12/18 |
Issue: | 47 |
First Page: | 273 |
Last Page: | 276 |
Note: | Part of special issue "26th European Conference on Solid-State Transducers, EUROSENSOR 2012" |
Link: | https://doi.org/10.1016/j.proeng.2012.09.136 |
Zugriffsart: | campus |
Institutes: | FH Aachen / Fachbereich Medizintechnik und Technomathematik |
FH Aachen / INB - Institut für Nano- und Biotechnologien | |
collections: | Verlag / Elsevier |