The search result changed since you submitted your search request. Documents might be displayed in a different sort order.
  • search hit 5 of 222
Back to Result List

Modelling of Soft Connective Tissues to Investigate Female Pelvic Floor Dysfunctions

  • After menopause, decreased levels of estrogen and progesterone remodel the collagen of the soft tissues thereby reducing their stiffness. Stress urinary incontinence is associated with involuntary urine leakage due to pathological movement of the pelvic organs resulting from lax suspension system, fasciae, and ligaments. This study compares the changes in the orientation and position of the female pelvic organs due to weakened fasciae, ligaments, and their combined laxity. A mixture theory weighted by respective volume fraction of elastin-collagen fibre compound (5%), adipose tissue (85%), and smooth muscle (5%) is adopted to characterize the mechanical behaviour of the fascia. The load carrying response (other than the functional response to the pelvic organs) of each fascia component, pelvic organs, muscles, and ligaments are assumed to be isotropic, hyperelastic, and incompressible. Finite element simulations are conducted during Valsalva manoeuvre with weakened tissues modelled by reduced tissue stiffness. A significant dislocation of the urethrovesical junction is observed due to weakness of the fascia (13.89 mm) compared to the ligaments (5.47 mm). The dynamics of the pelvic floor observed in this study during Valsalva manoeuvre is associated with urethral-bladder hypermobility, greater levator plate angulation, and positive Q-tip test which are observed in incontinent females.

Export metadata

Additional Services

Share in Twitter Search Google Scholar
Metadaten
Author:Aroj BhattaraiORCiD, Manfred StaatORCiD
DOI:https://doi.org/10.1155/2018/9518076
ISSN:1748-6718
Parent Title (English):Computational and Mathematical Methods in Medicine
Publisher:Hindawi
Place of publication:New York, NY
Document Type:Article
Language:English
Year of Completion:2018
Date of the Publication (Server):2018/01/16
Volume:2018
Issue:Article ID 9518076
First Page:1
Last Page:16
Link:http://doi.org/10.1155/2018/9518076
Zugriffsart:weltweit
Institutes:FH Aachen / Fachbereich Medizintechnik und Technomathematik
FH Aachen / IfB - Institut für Bioengineering
collections:Verlag / Hindawi
Open Access / Gold
Licence (German):License LogoCreative Commons - Namensnennung