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An examination of tissue engineered scaffolds in a bioreactor

  • Replacement tissues, designed to fill in articular cartilage defects, should exhibit the same properties as the native material. The aim of this study is to foster the understanding of, firstly, the mechanical behavior of the material itself and, secondly, the influence of cultivation parameters on cell seeded implants as well as on cell migration into acellular implants. In this study, acellular cartilage replacement material is theoretically, numerically and experimentally investigated regarding its viscoelastic properties, where a phenomenological model for practical applications is developed. Furthermore, remodeling and cell migration are investigated.

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Metadaten
Author:Angela Niedermeyer, Bei Zhou, Gözde Dursun, Aysegül Temiz ArtmannORCiD, Bernd Markert
DOI:https://doi.org/10.1002/pamm.201610038
ISSN:1617-7061
Parent Title (English):Proceedings in Applied Mathematics and Mechanics PAMM
Publisher:Wiley-VCH
Place of publication:Weinheim
Document Type:Article
Language:English
Year of Completion:2016
Date of the Publication (Server):2016/11/10
Volume:16
Issue:1
First Page:99
Last Page:100
Note:
Joint Annual Meeting of DMV and GAMM 2016, 87th Annual Meeting of the International Association of Applied Mathematics and Mechanics (GAMM) and Deutsche Mathematiker-Vereinigung (DMV), Braunschweig, DE, Mar 7-11, 2016
Link:https://doi.org/10.1002/pamm.201610038
Zugriffsart:weltweit
Institutes:FH Aachen / Fachbereich Chemie und Biotechnologie
FH Aachen / IfB - Institut für Bioengineering
collections:Verlag / Wiley-VCH