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Sterilization of Objects, Products, and Packaging Surfaces and Their Characterization in Different Fields of Industry: The Status in 2020

  • The treatment method to deactivate viable microorganisms from objects or products is termed sterilization. There are multiple forms of sterilization, each intended to be applied for a specific target, which depends on—but not limited to—the thermal, physical, and chemical stability of that target. Herein, an overview on the currently used sterilization processes in the global market is provided. Different sterilization techniques are grouped under a category that describes the method of treatment: radiation (gamma, electron beam, X-ray, and ultraviolet), thermal (dry and moist heat), and chemical (ethylene oxide, ozone, chlorine dioxide, and hydrogen peroxide). For each sterilization process, the typical process parameters as defined by regulations and the mode of antimicrobial activity are summarized. Finally, the recommended microorganisms that are used as biological indicators to validate sterilization processes in accordance with the rules that are established by various regulatory agencies are summarized.

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Metadaten
Author:Zaid B. Jildeh, Patrick H. Wagner, Michael Josef SchöningORCiD
DOI:https://doi.org/10.1002/pssa.202000732
ISSN:1862-6319
Parent Title (English):physica status solidi (a) applications and materials science
Publisher:Wiley-VCH
Place of publication:Weinheim
Document Type:Article
Language:English
Year of Completion:2021
Date of the Publication (Server):2021/03/26
Tag:bioburdens; sterility tests; sterilization efficacy; sterilization methods; validation methods
Volume:218
Issue:13
Length:27 Seiten
Note:
Corresponding author: Michael J. Schöning
Link:https://doi.org/10.1002/pssa.202000732
Zugriffsart:weltweit
Institutes:FH Aachen / Fachbereich Medizintechnik und Technomathematik
FH Aachen / INB - Institut für Nano- und Biotechnologien
collections:Verlag / Wiley-VCH
Open Access / Hybrid
Licence (German):License LogoCreative Commons - Namensnennung-Nicht kommerziell