Surface functionalization for spore-based biosensors with organosilanes

  • In the present work, surface functionalization of different sensor materials was studied. Organosilanes are well known to serve as coupling agent for biomolecules or cells on inorganic materials. 3-aminopropyltriethoxysilane (APTES) was used to attach microbiological spores time to an interdigitated sensor surface. The functionality and physical properties of APTES were studied on isolated sensor materials, namely silicon dioxide (SiO2) and platinum (Pt) as well as the combined material on sensor level. A predominant immobilization of spores could be demonstrated on SiO2 surfaces. Additionally, the impedance signal of APTES-functionalized biosensor chips has been investigated.

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Metadaten
Author:Julio Arreola, Jan OberländerORCiD, M. Mätzkow, Michael Keusgen, Michael Josef SchöningORCiD
DOI:https://doi.org/10.1016/j.electacta.2017.04.157
ISSN:0013-4686
Parent Title (English):Electrochimica Acta
Publisher:Elsevier
Place of publication:Amsterdam
Document Type:Article
Language:English
Year of Completion:2017
Volume:241
First Page:237
Last Page:243
Link:https://doi.org/10.1016/j.electacta.2017.04.157
Zugriffsart:campus
Institutes:FH Aachen / Fachbereich Medizintechnik und Technomathematik
FH Aachen / INB - Institut für Nano- und Biotechnologien
collections:Verlag / Elsevier