Detection of Adrenaline Based on Bioelectrocatalytical System to Support Tumor Diagnostic Technology

  • An amperometric biosensor based on the bioelectrocatalytic measurement principle for the detection of adrenaline has been developed. The adrenaline sensor has been prepared by modification of a platinum thin-film electrode with a pyrroloquinoline quinone-dependent glucose dehydrogenase. The enzyme was immobilized via cross-linking method. Lower detection limit of 1 nM of adrenaline has been achieved by measuring at physiological level at pH 7.4.

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Metadaten
Author:Denise MolinnusORCiD, Gabriel Hardt, Larissa Käver, Holger S. Willenberg, Arshak PoghossianORCiD, Michael Keusgen, Michael Josef SchöningORCiD
DOI:https://doi.org/10.3390/proceedings1040506
Parent Title (English):Proceedings, 2017, Eurosensors 2017
Publisher:MDPI
Place of publication:Basel
Document Type:Conference Proceeding
Language:English
Year of Completion:2017
Tag:adrenaline; bioelectrocatalysis; chip-based biosensor; glucose dehydrogenase
Volume:1
Issue:4
Length:4 Seiten
Note:
Eurosensors 2017 Conference, Paris, France, 3–6 September 2017
Link:https://doi.org/10.3390/proceedings1040506
Zugriffsart:weltweit
Institutes:FH Aachen / Fachbereich Medizintechnik und Technomathematik
FH Aachen / INB - Institut für Nano- und Biotechnologien
open_access (DINI-Set):open_access
collections:Verlag / MDPI
Licence (German): Creative Commons - Namensnennung

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