Lateral resolution enhancement of pulse-driven light-addressable potentiometric sensor

  • To study chemical and biological processes, spatially resolved determination of the concentrations of one or more analyte species is of distinct interest. With a light-addressable potentiometric sensor (LAPS), chemical images can be created, which visualize the concentration distribution above the sensor plate. One important challenge is to achieve a good lateral resolution in order to detect events that take place in a small and limited region. LAPS utilizes a focused light spot to address the measurement region. By moving this light spot along the semiconductor sensor plate, the concentration distribution can be observed. In this study, we show that utilizing a pulse as light excitation instead of a traditionally used continuously modulated light excitation, the lateral resolution can be improved by a factor of 6 or more.

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Metadaten
Author:Frederik WernerORCiD, Ko-ichiro Miyamoto, Torsten WagnerORCiD, Michael Josef SchöningORCiD, Tatsuo Yoshinobu
DOI:https://doi.org/10.1016/j.snb.2017.02.057
ISSN:0925-4005
Parent Title (English):Sensor and Actuators B: Chemical
Publisher:Elsevier
Place of publication:Amsterdam
Document Type:Article
Language:English
Year of Completion:2017
Tag:Chemical images; LAPS; Light-addressable potentiometric sensor
Volume:248
First Page:961
Last Page:965
Link:https://doi.org/10.1016/j.snb.2017.02.057
Zugriffsart:campus
Institutes:FH Aachen / Fachbereich Medizintechnik und Technomathematik
FH Aachen / INB - Institut für Nano- und Biotechnologien
collections:Verlag / Elsevier